KNG1 (kininogen 1) - Rat Genome Database

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Gene: KNG1 (kininogen 1) Sus scrofa
Analyze
Symbol: KNG1
Name: kininogen 1
RGD ID: 13848418
Description: ENCODES a protein that exhibits cysteine-type endopeptidase inhibitor activity (ortholog); protease binding (ortholog); INVOLVED IN antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); Factor XII activation (ortholog); inflammatory response (ortholog); PARTICIPATES IN kallikrein-kinin cascade pathway; kinin signaling pathway; syndecan signaling pathway; ASSOCIATED WITH 3MC syndrome 1 (ortholog); acquired angioedema (ortholog); acute kidney failure (ortholog); FOUND IN extracellular space (ortholog); intracellular membrane-bounded organelle (ortholog); perikaryon (ortholog); INTERACTS WITH benazepril; clofibrate; enalaprilat dihydrate
Type: protein-coding
RefSeq Status: MODEL
Previously known as: kininogen-1; KNG; low molecular weight kininogen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,521,340 - 124,557,958 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,521,276 - 124,557,384 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,911,227 - 133,947,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:13679312   PMID:14681463  


Genomics

Comparative Map Data
KNG1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13124,521,340 - 124,557,958 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113124,521,276 - 124,557,384 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213133,911,227 - 133,947,757 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KNG1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383186,717,359 - 186,744,410 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3186,717,348 - 186,744,410 (+)EnsemblGRCh38hg38GRCh38
GRCh373186,435,148 - 186,462,199 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363187,917,814 - 187,944,437 (+)NCBINCBI36hg18NCBI36
Celera3184,871,536 - 184,898,662 (+)NCBI
Cytogenetic Map3q27.3NCBI
HuRef3183,844,775 - 183,871,713 (+)NCBIHuRef
CHM1_13186,399,036 - 186,425,781 (+)NCBICHM1_1
T2T-CHM13v2.03189,539,122 - 189,566,165 (+)NCBI
Kng2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391622,804,602 - 22,847,851 (-)NCBIGRCm39mm39
GRCm39 Ensembl1622,804,604 - 22,848,232 (-)Ensembl
GRCm381622,985,852 - 23,029,101 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1622,985,854 - 23,029,482 (-)EnsemblGRCm38mm10GRCm38
MGSCv371622,985,925 - 23,029,174 (-)NCBIGRCm37mm9NCBIm37
MGSCv361622,902,680 - 22,944,351 (-)NCBImm8
Celera1623,545,793 - 23,588,919 (-)NCBICelera
Cytogenetic Map16B1NCBI
Kng2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21177,913,876 - 77,936,247 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1177,909,612 - 78,002,971 (+)Ensembl
Rnor_6.01181,509,185 - 81,516,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01184,605,412 - 84,612,986 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41180,109,499 - 80,131,887 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11180,167,317 - 80,189,475 (+)NCBI
Celera1176,789,106 - 76,811,459 (+)NCBICelera
Cytogenetic Map11q23NCBI
Kng1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542020,989,197 - 21,016,084 (-)NCBIChiLan1.0ChiLan1.0
KNG1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13192,219,675 - 192,245,318 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3192,219,462 - 192,245,149 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03183,751,598 - 183,778,655 (+)NCBIMhudiblu_PPA_v0panPan3
KNG1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13419,288,629 - 19,318,096 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3419,287,109 - 19,318,081 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3423,373,992 - 23,403,581 (+)NCBI
ROS_Cfam_1.03419,199,856 - 19,229,431 (+)NCBI
ROS_Cfam_1.0 Ensembl3419,199,904 - 19,229,419 (+)Ensembl
UMICH_Zoey_3.13419,231,763 - 19,260,578 (+)NCBI
UNSW_CanFamBas_1.03419,231,843 - 19,260,884 (+)NCBI
UU_Cfam_GSD_1.03419,460,203 - 19,488,753 (+)NCBI
Kng1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602117,161,767 - 117,189,596 (-)NCBI
SpeTri2.0NW_0049365783,255,335 - 3,281,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KNG1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11581,002,287 - 81,027,893 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604154,492,596 - 54,518,121 (+)NCBIVero_WHO_p1.0
Kng1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473070,022,449 - 70,065,115 (-)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system nervous system renal system reproductive system respiratory system
High
Medium 1 2
Low 4 1 1
Below cutoff 3 1 3 2 5 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012914   ⟹   ENSSSCP00000012573
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,362 - 124,557,037 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000036812   ⟹   ENSSSCP00000043463
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,353 - 124,557,956 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000046736   ⟹   ENSSSCP00000051218
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,830 - 124,557,053 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000066840   ⟹   ENSSSCP00000069533
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,277 - 124,555,923 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000076765   ⟹   ENSSSCP00000061752
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,340 - 124,557,958 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000086155   ⟹   ENSSSCP00000059888
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13124,521,353 - 124,557,956 (+)Ensembl
RefSeq Acc Id: XM_003483288   ⟹   XP_003483336
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113124,521,282 - 124,557,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005652370   ⟹   XP_005652427
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113124,521,282 - 124,557,384 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013988208   ⟹   XP_013843662
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113124,521,276 - 124,557,382 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003483336 (Get FASTA)   NCBI Sequence Viewer  
  XP_005652427 (Get FASTA)   NCBI Sequence Viewer  
  XP_013843662 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAP85260 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013843662   ⟸   XM_013988208
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003483336   ⟸   XM_003483288
- Peptide Label: isoform X2
- UniProtKB: A0A287AHT8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005652427   ⟸   XM_005652370
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSSSCP00000069533   ⟸   ENSSSCT00000066840
RefSeq Acc Id: ENSSSCP00000061752   ⟸   ENSSSCT00000076765
RefSeq Acc Id: ENSSSCP00000059888   ⟸   ENSSSCT00000086155
RefSeq Acc Id: ENSSSCP00000043463   ⟸   ENSSSCT00000036812
RefSeq Acc Id: ENSSSCP00000012573   ⟸   ENSSSCT00000012914
RefSeq Acc Id: ENSSSCP00000051218   ⟸   ENSSSCT00000046736
Protein Domains
Cystatin kininogen-type


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011802 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00025001291 UniProtKB/TrEMBL
  ENSSSCG00030011622 UniProtKB/TrEMBL
  ENSSSCG00035035363 UniProtKB/TrEMBL
  ENSSSCG00040067108 UniProtKB/TrEMBL
  ENSSSCG00045031870 UniProtKB/TrEMBL
  ENSSSCG00050041879 UniProtKB/TrEMBL
  ENSSSCG00055017387 UniProtKB/TrEMBL
  ENSSSCG00060045787 UniProtKB/TrEMBL
  ENSSSCG00070016413 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012573.4 UniProtKB/TrEMBL
  ENSSSCP00000043463 ENTREZGENE
  ENSSSCP00000043463.1 UniProtKB/TrEMBL
  ENSSSCP00000051218.1 UniProtKB/TrEMBL
  ENSSSCP00000059888.1 UniProtKB/TrEMBL
  ENSSSCP00000061752 ENTREZGENE
  ENSSSCP00000061752.1 UniProtKB/TrEMBL
  ENSSSCP00000069533.1 UniProtKB/TrEMBL
  ENSSSCP00025000508.1 UniProtKB/TrEMBL
  ENSSSCP00025000520.1 UniProtKB/TrEMBL
  ENSSSCP00025000528.1 UniProtKB/TrEMBL
  ENSSSCP00025000537.1 UniProtKB/TrEMBL
  ENSSSCP00025000549.1 UniProtKB/TrEMBL
  ENSSSCP00030007145.1 UniProtKB/TrEMBL
  ENSSSCP00030007151.1 UniProtKB/TrEMBL
  ENSSSCP00030007152.1 UniProtKB/TrEMBL
  ENSSSCP00030007155.1 UniProtKB/TrEMBL
  ENSSSCP00030007158.1 UniProtKB/TrEMBL
  ENSSSCP00035018738.1 UniProtKB/TrEMBL
  ENSSSCP00035018741.1 UniProtKB/TrEMBL
  ENSSSCP00035018742.1 UniProtKB/TrEMBL
  ENSSSCP00035018746.1 UniProtKB/TrEMBL
  ENSSSCP00035018750.1 UniProtKB/TrEMBL
  ENSSSCP00040040487.1 UniProtKB/TrEMBL
  ENSSSCP00040040560.1 UniProtKB/TrEMBL
  ENSSSCP00040040679.1 UniProtKB/TrEMBL
  ENSSSCP00040040742.1 UniProtKB/TrEMBL
  ENSSSCP00040040833.1 UniProtKB/TrEMBL
  ENSSSCP00040040891.1 UniProtKB/TrEMBL
  ENSSSCP00045037916.1 UniProtKB/TrEMBL
  ENSSSCP00045038046.1 UniProtKB/TrEMBL
  ENSSSCP00045038131.1 UniProtKB/TrEMBL
  ENSSSCP00045038218.1 UniProtKB/TrEMBL
  ENSSSCP00045038301.1 UniProtKB/TrEMBL
  ENSSSCP00050024244.1 UniProtKB/TrEMBL
  ENSSSCP00050024252.1 UniProtKB/TrEMBL
  ENSSSCP00050024255.1 UniProtKB/TrEMBL
  ENSSSCP00050024258.1 UniProtKB/TrEMBL
  ENSSSCP00050024260.1 UniProtKB/TrEMBL
  ENSSSCP00055027147.1 UniProtKB/TrEMBL
  ENSSSCP00055027241.1 UniProtKB/TrEMBL
  ENSSSCP00055027391.1 UniProtKB/TrEMBL
  ENSSSCP00055027438.1 UniProtKB/TrEMBL
  ENSSSCP00055027523.1 UniProtKB/TrEMBL
  ENSSSCP00055027614.1 UniProtKB/TrEMBL
  ENSSSCP00055027704.1 UniProtKB/TrEMBL
  ENSSSCP00060026620.1 UniProtKB/TrEMBL
  ENSSSCP00060026627.1 UniProtKB/TrEMBL
  ENSSSCP00060026630.1 UniProtKB/TrEMBL
  ENSSSCP00060026635.1 UniProtKB/TrEMBL
  ENSSSCP00060026639.1 UniProtKB/TrEMBL
  ENSSSCP00070027060.1 UniProtKB/TrEMBL
  ENSSSCP00070027079.1 UniProtKB/TrEMBL
  ENSSSCP00070027084.1 UniProtKB/TrEMBL
  ENSSSCP00070027097.1 UniProtKB/TrEMBL
  ENSSSCP00070027112.1 UniProtKB/TrEMBL
  ENSSSCP00070027117.1 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012914.4 UniProtKB/TrEMBL
  ENSSSCT00000036812 ENTREZGENE
  ENSSSCT00000036812.2 UniProtKB/TrEMBL
  ENSSSCT00000046736.1 UniProtKB/TrEMBL
  ENSSSCT00000066840.1 UniProtKB/TrEMBL
  ENSSSCT00000076765 ENTREZGENE
  ENSSSCT00000076765.1 UniProtKB/TrEMBL
  ENSSSCT00000086155.1 UniProtKB/TrEMBL
  ENSSSCT00025001626.1 UniProtKB/TrEMBL
  ENSSSCT00025001666.1 UniProtKB/TrEMBL
  ENSSSCT00025001686.1 UniProtKB/TrEMBL
  ENSSSCT00025001715.1 UniProtKB/TrEMBL
  ENSSSCT00025001741.1 UniProtKB/TrEMBL
  ENSSSCT00030015948.1 UniProtKB/TrEMBL
  ENSSSCT00030015963.1 UniProtKB/TrEMBL
  ENSSSCT00030015966.1 UniProtKB/TrEMBL
  ENSSSCT00030015973.1 UniProtKB/TrEMBL
  ENSSSCT00030015978.1 UniProtKB/TrEMBL
  ENSSSCT00035046872.1 UniProtKB/TrEMBL
  ENSSSCT00035046880.1 UniProtKB/TrEMBL
  ENSSSCT00035046882.1 UniProtKB/TrEMBL
  ENSSSCT00035046891.1 UniProtKB/TrEMBL
  ENSSSCT00035046898.1 UniProtKB/TrEMBL
  ENSSSCT00040091767.1 UniProtKB/TrEMBL
  ENSSSCT00040091922.1 UniProtKB/TrEMBL
  ENSSSCT00040092197.1 UniProtKB/TrEMBL
  ENSSSCT00040092308.1 UniProtKB/TrEMBL
  ENSSSCT00040092497.1 UniProtKB/TrEMBL
  ENSSSCT00040092600.1 UniProtKB/TrEMBL
  ENSSSCT00045054448.1 UniProtKB/TrEMBL
  ENSSSCT00045054625.1 UniProtKB/TrEMBL
  ENSSSCT00045054732.1 UniProtKB/TrEMBL
  ENSSSCT00045054842.1 UniProtKB/TrEMBL
  ENSSSCT00045054950.1 UniProtKB/TrEMBL
  ENSSSCT00050056855.1 UniProtKB/TrEMBL
  ENSSSCT00050056865.1 UniProtKB/TrEMBL
  ENSSSCT00050056870.1 UniProtKB/TrEMBL
  ENSSSCT00050056878.1 UniProtKB/TrEMBL
  ENSSSCT00050056880.1 UniProtKB/TrEMBL
  ENSSSCT00055034168.1 UniProtKB/TrEMBL
  ENSSSCT00055034293.1 UniProtKB/TrEMBL
  ENSSSCT00055034482.1 UniProtKB/TrEMBL
  ENSSSCT00055034542.1 UniProtKB/TrEMBL
  ENSSSCT00055034662.1 UniProtKB/TrEMBL
  ENSSSCT00055034769.1 UniProtKB/TrEMBL
  ENSSSCT00055034880.1 UniProtKB/TrEMBL
  ENSSSCT00060062133.1 UniProtKB/TrEMBL
  ENSSSCT00060062152.1 UniProtKB/TrEMBL
  ENSSSCT00060062157.1 UniProtKB/TrEMBL
  ENSSSCT00060062168.1 UniProtKB/TrEMBL
  ENSSSCT00060062177.1 UniProtKB/TrEMBL
  ENSSSCT00070032418.1 UniProtKB/TrEMBL
  ENSSSCT00070032442.1 UniProtKB/TrEMBL
  ENSSSCT00070032449.1 UniProtKB/TrEMBL
  ENSSSCT00070032463.1 UniProtKB/TrEMBL
  ENSSSCT00070032481.1 UniProtKB/TrEMBL
  ENSSSCT00070032487.1 UniProtKB/TrEMBL
InterPro Cystatin_dom UniProtKB/TrEMBL
  Cystatin_sf UniProtKB/TrEMBL
  Kininogen UniProtKB/TrEMBL
  Kininogen-type_cystatin_dom UniProtKB/TrEMBL
KEGG Report ssc:396568 UniProtKB/TrEMBL
NCBI Gene KNG1 ENTREZGENE
Pfam Cystatin UniProtKB/TrEMBL
PRINTS KININOGEN UniProtKB/TrEMBL
PROSITE CYSTATIN_KININOGEN UniProtKB/TrEMBL
SMART SM00043 UniProtKB/TrEMBL
Superfamily-SCOP SSF54403 UniProtKB/TrEMBL
UniProt A0A287AHT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A287B546_PIG UniProtKB/TrEMBL
  A0A4X1UDI9_PIG UniProtKB/TrEMBL
  A0A4X1UF91_PIG UniProtKB/TrEMBL
  A0A4X1UFA7_PIG UniProtKB/TrEMBL
  A0A4X1UGF5_PIG UniProtKB/TrEMBL
  A0A4X1UGH1_PIG UniProtKB/TrEMBL
  A0A4X1UGH5_PIG UniProtKB/TrEMBL
  A0A5G2Q763_PIG UniProtKB/TrEMBL
  A0A5G2QBB0_PIG UniProtKB/TrEMBL
  A0A5G2QZH2_PIG UniProtKB/TrEMBL
  A0A8D0QEN4_PIG UniProtKB/TrEMBL
  A0A8D0UFA3_PIG UniProtKB/TrEMBL
  A0A8D0UFA4_PIG UniProtKB/TrEMBL
  A0A8D0ZQV2_PIG UniProtKB/TrEMBL
  A0A8D1FQ18_PIG UniProtKB/TrEMBL
  A0A8D1IVL5_PIG UniProtKB/TrEMBL
  A0A8D1QVN2_PIG UniProtKB/TrEMBL
  A0A8D1R1V5_PIG UniProtKB/TrEMBL
  A0A8D1R6P3_PIG UniProtKB/TrEMBL
  A0A8D1VMJ2_PIG UniProtKB/TrEMBL
  F1SFI4_PIG UniProtKB/TrEMBL
VGNC ID VGNC:89557 ENTREZGENE