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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:oxylipin
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Accession:CHEBI:61121 term browser browse the term
Definition:Any member of the group of bioactive lipids made by oxidation of polyunsaturated fatty acids.
Synonyms:related_synonym: oxylipins
 xref: PMID:11960741
 cyclic_relationship: is_conjugate_acid_of CHEBI:62933


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leukotriene A4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox5 arachidonate 5-lipoxygenase increases chemical synthesis ISO ALOX5 protein results in increased chemical synthesis of Leukotriene A4 CTD PMID:18295198 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Lta4h leukotriene A4 hydrolase multiple interactions
increases hydrolysis		 ISO cyclohexene inhibits the reaction [LTA4H protein results in increased hydrolysis of Leukotriene A4]; Oxygen inhibits the reaction [LTA4H protein results in increased hydrolysis of Leukotriene A4]; Piperonyl Butoxide inhibits the reaction [LTA4H protein results in increased hydrolysis of Leukotriene A4]; propanethiol inhibits the reaction [LTA4H protein results in increased hydrolysis of Leukotriene A4] CTD PMID:2827578 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 decreases activity EXP Leukotriene A4 results in decreased activity of MGST1 protein CTD PMID:9890956 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
prostaglandin H2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstm2 glutathione S-transferase mu 2 affects metabolic processing ISO GSTM2 protein affects the metabolism of Prostaglandin H2 CTD PMID:10905636 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 affects metabolic processing ISO GSTM3 protein affects the metabolism of Prostaglandin H2 CTD PMID:10905636 NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Ptgds prostaglandin D2 synthase increases metabolic processing EXP PTGDS protein results in increased metabolism of Prostaglandin H2 CTD PMID:22043816 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      atom 19919
        nonmetal atom 19848
          carbon atom 19801
            organic molecular entity 19801
              lipid 18000
                fatty acid 16848
                  oxylipin 6
                    (+)-7-isojasmonic acid + 0
                    (+)-vernolic acid 0
                    (10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid 0
                    15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid 0
                    19-hydroxyprostaglandin H1 0
                    19-hydroxyprostaglandin H2 0
                    5,6-Ep-15S-HETE 0
                    arabidopside + 0
                    eoxin A4 0
                    leukotriene A4 + 3
                    prostaglandin H1 + 0
                    prostaglandin H2 + 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            heteroorganic entity 19558
                              organochalcogen compound 19317
                                organooxygen compound 19233
                                  carbon oxoacid 18695
                                    carboxylic acid 18692
                                      monocarboxylic acid 18028
                                        fatty acid 16848
                                          oxylipin 6
                                            (+)-7-isojasmonic acid + 0
                                            (+)-vernolic acid 0
                                            (10E,15Z)-9,12,13-trihydroxy-10,15-octadecadienoic acid 0
                                            15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid 0
                                            19-hydroxyprostaglandin H1 0
                                            19-hydroxyprostaglandin H2 0
                                            5,6-Ep-15S-HETE 0
                                            arabidopside + 0
                                            eoxin A4 0
                                            leukotriene A4 + 3
                                            prostaglandin H1 + 0
                                            prostaglandin H2 + 3
paths to the root