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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 13886591
Species: Sus scrofa
RGD Object: Gene
Symbol: CYP17A1
Name: cytochrome P450 family 17 subfamily A member 1
Acc ID: CHEBI:27485
Term: prostaglandin J2
Definition: A member of the class of prostaglandins J that consists of prosta-5,9,13-trien-1-oic acid substituted by an oxo group at position 11 and a hydroxy group at position 15 (the 5Z,13E,15S stereoisomer).
Chemical ID: MESH:C037112
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP17A1multiple interactionsEXP 6480464CTD9-deoxy-delta-9-prostaglandin D2 inhibits the reaction [[LHB protein co-treated with INS protein] results in increased expression of CYP17A1 mRNA]PMID:11889176
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