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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:halo fatty acid
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Accession:CHEBI:60692 term browser browse the term
Definition:Any fatty acid carrying at least one halo substituent.
Synonyms:related_synonym: halo FA;   halo fatty acids;   halogenated FA;   halogenated fatty acid;   halogenated fatty acids
 xref: PMID:13183268


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2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 decreases expression EXP 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity EXP 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr12:22,104,163...22,118,294
Ensembl chr12:22,104,219...22,118,288 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity
multiple interactions		 ISO 2-bromopalmitate results in increased activity of PPARD protein
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]		 CTD PMID:15997096 PMID:21543282 PMID:23150725 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712 		JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19740
    chemical entity 19738
      atom 19738
        nonmetal atom 19678
          carbon atom 19627
            organic molecular entity 19627
              lipid 17797
                fatty acid 16519
                  halo fatty acid 20
                    2-Hydroxy-3-chloropenta-2,4-dienoate 0
                    3,5-Dichloro-2-methylmuconate 0
                    3,5-Dichloro-2-methylmuconolactone 0
                    3-Chloro-2-methyldienelactone 0
                    3-Chloro-2-methylmaleylacetate 0
                    3-Fluoro-cis,cis-muconate 0
                    bromo fatty acid + 20
                    fluoro fatty acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19740
    subatomic particle 19738
      composite particle 19738
        hadron 19738
          baryon 19738
            nucleon 19738
              atomic nucleus 19738
                atom 19738
                  main group element atom 19686
                    p-block element atom 19686
                      carbon group element atom 19631
                        carbon atom 19627
                          organic molecular entity 19627
                            organic group 18846
                              organic divalent group 18832
                                organodiyl group 18832
                                  carbonyl group 18798
                                    carbonyl compound 18798
                                      carboxylic acid 18518
                                        monocarboxylic acid 17852
                                          fatty acid 16519
                                            halo fatty acid 20
                                              2-Hydroxy-3-chloropenta-2,4-dienoate 0
                                              3,5-Dichloro-2-methylmuconate 0
                                              3,5-Dichloro-2-methylmuconolactone 0
                                              3-Chloro-2-methyldienelactone 0
                                              3-Chloro-2-methylmaleylacetate 0
                                              3-Fluoro-cis,cis-muconate 0
                                              bromo fatty acid + 20
                                              fluoro fatty acid + 0
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