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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:halo fatty acid
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Accession:CHEBI:60692 term browser browse the term
Definition:Any fatty acid carrying at least one halo substituent.
Synonyms:related_synonym: halo FA;   halo fatty acids;   halogenated FA;   halogenated fatty acid;   halogenated fatty acids
 xref: PMID:13183268

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2-bromohexadecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa1 apolipoprotein A1 decreases expression EXP 2-bromopalmitate results in decreased expression of APOA1 mRNA CTD PMID:7556148 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of CEBPB mRNA] CTD PMID:30076181 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO 2-bromopalmitate results in decreased expression of FAS mRNA CTD PMID:16712844 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases activity EXP 2-bromopalmitate results in increased activity of GAPDH protein CTD PMID:10650946 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IFIT3 mRNA] CTD PMID:30076181 NCBI chr 1:252,906,234...252,911,377
Ensembl chr 1:252,906,234...252,911,382 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:30076181 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531 		JBrowse link
G Lat2 linker for activation of T cells family, member 2 decreases expression ISO 2-bromopalmitate results in decreased expression of LAT2 protein CTD PMID:23001822 NCBI chr12:25,114,099...25,128,381
Ensembl chr12:25,119,355...25,125,749 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO 2-bromopalmitate results in increased expression of LDLR mRNA CTD PMID:23150725 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Lrat lecithin retinol acyltransferase increases expression EXP 2-bromopalmitate results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 2:181,896,304...181,905,366
Ensembl chr 2:181,896,305...181,905,300 		JBrowse link
G Ly6e lymphocyte antigen 6 family member E multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of LY6E mRNA] CTD PMID:30076181 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in decreased expression of MPO mRNA] CTD PMID:30076181 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260 		JBrowse link
G Ppard peroxisome proliferator-activated receptor delta increases activity
multiple interactions		 ISO 2-bromopalmitate results in increased activity of PPARD protein
2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein]		 CTD PMID:15997096, PMID:21543282, PMID:23150725 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression EXP 2-bromopalmitate results in increased expression of PPARG protein CTD PMID:10650946 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380 		JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions ISO 2-bromopalmitate binds to and results in increased expression of RARA protein; 2-bromopalmitate inhibits the reaction [Am 580 results in decreased expression of RARA protein]; 2-bromopalmitate inhibits the reaction [Tretinoin results in decreased expression of RARA protein]; [2-bromopalmitate results in increased susceptibility to Tretinoin] which results in increased expression of RARA protein CTD PMID:30076181 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210 		JBrowse link
G Rarb retinoic acid receptor, beta multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of RARB mRNA] CTD PMID:30076181 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 2-bromopalmitate results in increased expression of RBP1 mRNA CTD PMID:12576510 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842 		JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO 2-bromopalmitate results in increased activity of [RXRA protein binds to PPARD protein] CTD PMID:15997096 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908 		JBrowse link
G Spi1 Spi-1 proto-oncogene multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of SPI1 mRNA] CTD PMID:30076181 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO 2-bromopalmitate promotes the reaction [Tretinoin results in increased expression of TGM2 mRNA] CTD PMID:30076181 NCBI chr 3:154,597,165...154,627,257
Ensembl chr 3:154,597,168...154,627,257 		JBrowse link
G Ucp2 uncoupling protein 2 increases expression EXP 2-bromopalmitate results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 1:165,506,375...165,512,744
Ensembl chr 1:165,506,361...165,512,744 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19816
    chemical entity 19816
      atom 19814
        nonmetal atom 19690
          carbon atom 19597
            organic molecular entity 19597
              lipid 17059
                fatty acid 15990
                  halo fatty acid 20
                    2-Hydroxy-3-chloropenta-2,4-dienoate 0
                    3,5-Dichloro-2-methylmuconate 0
                    3,5-Dichloro-2-methylmuconolactone 0
                    3-Chloro-2-methyldienelactone 0
                    3-Chloro-2-methylmaleylacetate 0
                    3-Fluoro-cis,cis-muconate 0
                    bromo fatty acid + 20
                    fluoro fatty acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19816
    subatomic particle 19814
      composite particle 19814
        hadron 19814
          baryon 19814
            nucleon 19814
              atomic nucleus 19814
                atom 19814
                  main group element atom 19702
                    p-block element atom 19702
                      carbon group element atom 19608
                        carbon atom 19597
                          organic molecular entity 19597
                            organic group 18537
                              organic divalent group 18530
                                organodiyl group 18530
                                  carbonyl group 18436
                                    carbonyl compound 18436
                                      carboxylic acid 18114
                                        monocarboxylic acid 17476
                                          fatty acid 15990
                                            halo fatty acid 20
                                              2-Hydroxy-3-chloropenta-2,4-dienoate 0
                                              3,5-Dichloro-2-methylmuconate 0
                                              3,5-Dichloro-2-methylmuconolactone 0
                                              3-Chloro-2-methyldienelactone 0
                                              3-Chloro-2-methylmaleylacetate 0
                                              3-Fluoro-cis,cis-muconate 0
                                              bromo fatty acid + 20
                                              fluoro fatty acid 0
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