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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of B cell activation
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Accession:GO:0050871 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of B cell activation.
Synonyms:exact_synonym: positive regulation of B lymphocyte activation;   up regulation of B cell activation;   upregulation of B cell activation
 narrow_synonym: activation of B cell activation;   stimulation of B cell activation


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positive regulation of B cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akirin2 akirin 2 involved_in IMP (MGI:6855963|PMID:26041538) UniProt PMID:26041538 MGI:6855963 NCBI chr 4:34,550,615...34,566,930
Ensembl chr 4:34,550,937...34,566,908 		JBrowse link
G Cd81 CD81 antigen involved_in IMP (MGI:5476553|PMID:23499492) UniProt PMID:23499492 MGI:5476553 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Ighg2a immunoglobulin heavy constant gamma 2A acts_upstream_of_or_within IDA (PMID:11854359) MGI PMID:11854359
G Ighm immunoglobulin heavy constant mu acts_upstream_of_or_within IDA (PMID:10704460), (PMID:11854359), (PMID:8566034) MGI PMID:8566034 PMID:10704460 PMID:11854359 NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:16129705), (PMID:8566034), (PMID:9798653) MGI PMID:8566034 PMID:9798653 PMID:16129705 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il6 interleukin 6 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 8:89,373,943...89,415,103
Ensembl chr 8:89,373,943...89,415,102 		JBrowse link
G Peli1 pellino 1 acts_upstream_of_or_within IMP (PMID:19734906) MGI PMID:19734906 NCBI chr11:21,041,283...21,100,327
Ensembl chr11:21,041,291...21,100,323 		JBrowse link
G Sh3kbp1 SH3-domain kinase binding protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr  X:158,409,888...158,758,916
Ensembl chr  X:158,410,268...158,761,065 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within IMP (PMID:12855817) MGI PMID:12855817 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IDA (MGI:4942267|PMID:9670042) BHF-UCL PMID:9670042 MGI:4942267 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 involved_in IMP (MGI:3656197|PMID:16633345) UniProt PMID:16633345 MGI:3656197 NCBI chr 5:34,653,440...34,671,323
Ensembl chr 5:34,653,431...34,671,335 		JBrowse link
B cell costimulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd320 CD320 antigen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:34,062,065...34,068,748
Ensembl chr17:34,062,065...34,068,748 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:18762567) MGI PMID:18762567 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c acts_upstream_of_or_within
involved_in		 IDA
IBA		 (PMID:15240667) MGI
GO_Central		 PMID:15240667 GO_REF:0000033 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570 		JBrowse link
G Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b acts_upstream_of_or_within IDA (PMID:15240667) MGI PMID:15240667 NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072 		JBrowse link
positive regulation of B cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp11c ATPase, class VI, type 11C involved_in IMP (MGI:5002406|PMID:21423173) UniProt PMID:21423173 MGI:5002406 NCBI chr  X:59,268,643...59,450,041
Ensembl chr  X:59,268,650...59,636,304 		JBrowse link
G Bad BCL2-associated agonist of cell death acts_upstream_of_or_within IMP (PMID:12431371) MGI PMID:12431371 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Cd27 CD27 antigen involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 6:125,209,583...125,214,014
Ensembl chr 6:125,209,585...125,213,973 		JBrowse link
G Il21 interleukin 21 involved_in NAS (MGI:3505636|PMID:15494482) UniProt PMID:15494482 MGI:3505636 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il2rg interleukin 2 receptor, gamma chain acts_upstream_of_or_within IMP (PMID:9252128)
(PMID:23918385)		 MGI PMID:9252128 PMID:23918385 NCBI chr  X:100,307,991...100,311,861
Ensembl chr  X:100,307,984...100,311,861 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within IDA (PMID:16797412) MGI PMID:16797412 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:10704460), (PMID:9620849) GO_Central
MGI		 PMID:9620849 PMID:10704460 GO_REF:0000033 NCBI chr 1:87,548,034...87,648,232
Ensembl chr 1:87,548,034...87,648,229 		JBrowse link
G Mmp14 matrix metallopeptidase 14 (membrane-inserted) involved_in IMP (MGI:5013661|PMID:21572390) UniProt PMID:21572390 MGI:5013661 NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in IMP (MGI:3818191|PMID:19015308) UniProt PMID:19015308 MGI:3818191 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Pcid2 PCI domain containing 2 involved_in IMP (MGI:4839685|PMID:20870947) UniProt PMID:20870947 MGI:4839685 NCBI chr 8:13,125,476...13,155,343
Ensembl chr 8:13,127,189...13,155,459 		JBrowse link
G Pnp purine-nucleoside phosphorylase acts_upstream_of_or_within IMP (PMID:10859343) MGI PMID:10859343 NCBI chr14:51,181,760...51,190,869
Ensembl chr14:51,168,539...51,190,869 		JBrowse link
G Ppp2r3c protein phosphatase 2, regulatory subunit B'', gamma acts_upstream_of_or_within
involved_in		 IMP
IBA		 (PMID:16129705) MGI
GO_Central		 PMID:16129705 GO_REF:0000033 NCBI chr12:55,327,594...55,350,024
Ensembl chr12:55,325,776...55,349,783 		JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101 		JBrowse link
G Stat5a signal transducer and activator of transcription 5A acts_upstream_of_or_within IGI (PMID:10979977) MGI PMID:10979977 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995 		JBrowse link
G Stat5b signal transducer and activator of transcription 5B acts_upstream_of_or_within IGI (PMID:10979977) MGI PMID:10979977 NCBI chr11:100,671,557...100,741,407
Ensembl chr11:100,671,557...100,741,550 		JBrowse link
G Syk spleen tyrosine kinase involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:7477352)
(PMID:7477353)		 MGI PMID:7477352 PMID:7477353 GO_REF:0000119 MGI:4834177 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
positive regulation of B cell proliferation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ada adenosine deaminase acts_upstream_of_or_within IMP (PMID:14607964) MGI PMID:14607964 NCBI chr 2:163,565,703...163,592,154
Ensembl chr 2:163,568,504...163,592,159 		JBrowse link
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IMP (PMID:25404367) MGI PMID:25404367 NCBI chr11:79,980,205...80,026,623
Ensembl chr11:79,980,226...80,026,620 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IMP (PMID:9171827) MGI PMID:9171827 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Bmi1 Bmi1 polycomb ring finger oncogene involved_in IMP (MGI:3615850|PMID:15964995) HGNC-UCL PMID:15964995 MGI:3615850 NCBI chr 2:18,681,953...18,691,440
Ensembl chr 2:18,681,829...18,691,440 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 5:43,976,235...44,000,810
Ensembl chr 5:43,976,227...44,001,328 		JBrowse link
G Btk Bruton agammaglobulinemia tyrosine kinase involved_in ISO RGD
MGI		 PMID:28352114 GO_REF:0000096 MGI:4417868 RGD:151665126 NCBI chr  X:133,443,083...133,484,366
Ensembl chr  X:133,443,085...133,484,319 		JBrowse link
G Card11 caspase recruitment domain family, member 11 acts_upstream_of_or_within IMP (PMID:12867038) MGI PMID:12867038 NCBI chr 5:140,858,109...140,986,398
Ensembl chr 5:140,858,745...140,986,337 		JBrowse link
G Cd320 CD320 antigen involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:34,062,065...34,068,748
Ensembl chr17:34,062,065...34,068,748 		JBrowse link
G Cd38 CD38 antigen involved_in
acts_upstream_of_or_within		 ISO
IDA
IBA		 (PMID:8666928) MGI
GO_Central		 PMID:8666928 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717 		JBrowse link
G Cd40 CD40 antigen acts_upstream_of_or_within IDA
IGI		 (PMID:10979977), (PMID:11894097), (PMID:14607964), (PMID:8666928), (PMID:8920854)
(PMID:15963492)		 MGI PMID:8666928 PMID:8920854 PMID:10979977 PMID:11894097 PMID:14607964 More... NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Cd40lg CD40 ligand involved_in ISO RGD
MGI		 PMID:18384807 GO_REF:0000096 MGI:4417868 RGD:2313415 NCBI chr  X:56,257,448...56,269,402
Ensembl chr  X:56,257,503...56,269,402 		JBrowse link
G Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr18:60,936,921...60,945,724
Ensembl chr18:60,936,920...60,945,724 		JBrowse link
G Cd81 CD81 antigen involved_in TAS
ISO		 (MGI:3688380|PMID:14676841) UniProt
MGI		 PMID:14676841 GO_REF:0000119 MGI:3688380 MGI:4834177 NCBI chr 7:142,606,487...142,621,667
Ensembl chr 7:142,606,476...142,621,671 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A acts_upstream_of_or_within IGI (PMID:12970760) MGI PMID:12970760 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within IC
IGI		 (PMID:11222635)
(PMID:15963492)		 MGI PMID:11222635 PMID:15963492 NCBI chr 3:89,660,755...89,671,939
Ensembl chr 3:89,653,502...89,671,939 		JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in IDA
IBA		 (MGI:3777853|PMID:12023368) BHF-UCL
GO_Central		 PMID:12023368 GO_REF:0000033 MGI:3777853 NCBI chr19:4,264,479...4,273,548
Ensembl chr19:4,264,292...4,273,544 		JBrowse link
G Ephb2 Eph receptor B2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:136,374,850...136,563,637
Ensembl chr 4:136,374,850...136,563,299 		JBrowse link
G Gpr183 G protein-coupled receptor 183 involved_in IDA
ISO		 (MGI:5430842|PMID:21673108) UniProt
MGI		 PMID:21673108 GO_REF:0000119 MGI:4834177 MGI:5430842 NCBI chr14:122,189,743...122,202,605
Ensembl chr14:122,189,963...122,202,607 		JBrowse link
G Ighd immunoglobulin heavy constant delta acts_upstream_of_or_within IDA (PMID:8666928) MGI PMID:8666928 NCBI chr12:113,371,155...113,379,944
Ensembl chr12:113,370,224...113,379,944 		JBrowse link
G Ighm immunoglobulin heavy constant mu acts_upstream_of_or_within IDA (PMID:10704460), (PMID:10979977), (PMID:14607964), (PMID:15240667), (PMID:8552190), (PMID:8666928), (PMID:9254656) MGI PMID:8552190 PMID:8666928 PMID:9254656 PMID:10704460 PMID:10979977 More... NCBI chr12:113,382,446...113,386,350
Ensembl chr12:113,382,178...113,386,350 		JBrowse link
G Il13 interleukin 13 involved_in ISO requires CD40 antigen RGD
MGI		 PMID:10331006 PMID:11573960 GO_REF:0000096 MGI:4417868 RGD:61509 RGD:633067 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il13ra1 interleukin 13 receptor, alpha 1 ISO requires CD40 antigen RGD PMID:11573960 RGD:633067 NCBI chr  X:35,375,761...35,434,915
Ensembl chr  X:35,375,763...35,434,912 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within ISO (PMID:9184696) MGI PMID:9184696 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il21 interleukin 21 acts_upstream_of_or_within ISO MGI GO_REF:0000008 NCBI chr 3:37,276,908...37,286,785
Ensembl chr 3:37,276,908...37,286,785 		JBrowse link
G Il3 interleukin 3 acts_upstream_of_or_within IDA (PMID:7736574) MGI PMID:7736574 NCBI chr11:54,155,911...54,158,105
Ensembl chr11:54,156,129...54,158,103 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:10979977), (PMID:14607964) MGI PMID:10979977 PMID:14607964 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il5 interleukin 5 involved_in ISO RGD
MGI		 PMID:10529595 GO_REF:0000096 MGI:4417868 RGD:2303750 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933 		JBrowse link
G Il7 interleukin 7 acts_upstream_of_or_within IGI
IDA		 (PMID:7671324)
(PMID:12970760)		 MGI PMID:7671324 PMID:12970760 NCBI chr 3:7,637,088...7,678,820
Ensembl chr 3:7,635,054...7,678,820 		JBrowse link
G Irs2 insulin receptor substrate 2 involved_in IDA (MGI:4456946|PMID:15572028) BHF-UCL PMID:15572028 MGI:4456946 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP (MGI:3829850|PMID:18955699) UniProt PMID:18955699 MGI:3829850 NCBI chr13:83,652,136...83,815,197
Ensembl chr13:83,652,153...83,815,199 		JBrowse link
G Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:75,695,187...75,696,111
Ensembl chr10:75,695,187...75,696,074 		JBrowse link
G Nckap1l NCK associated protein 1 like involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr15:103,362,219...103,411,288
Ensembl chr15:103,362,221...103,407,237 		JBrowse link
G Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 2:168,318,330...168,443,900
Ensembl chr 2:168,318,330...168,443,577 		JBrowse link
G Peli1 pellino 1 acts_upstream_of_or_within IMP (PMID:19734906) MGI PMID:19734906 NCBI chr11:21,041,283...21,100,327
Ensembl chr11:21,041,291...21,100,323 		JBrowse link
G Prlr prolactin receptor involved_in ISO RGD
MGI		 PMID:8650199 PMID:9447986 GO_REF:0000096 MGI:4417868 RGD:151665811 RGD:151667430 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C involved_in
acts_upstream_of_or_within		 ISO
IMP		 (PMID:8566034), (PMID:9015183), (PMID:9254656)
(PMID:8666928)		 MGI PMID:8566034 PMID:8666928 PMID:9015183 PMID:9254656 GO_REF:0000119 MGI:4834177 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Sash3 SAM and SH3 domain containing 3 involved_in
acts_upstream_of_or_within		 IBA
IMP		 (PMID:16227612) GO_Central
MGI		 PMID:16227612 GO_REF:0000033 NCBI chr  X:47,235,313...47,250,442
Ensembl chr  X:47,235,313...47,250,442 		JBrowse link
G Slc39a10 solute carrier family 39 (zinc transporter), member 10 acts_upstream_of_or_within IMP (PMID:25074919) MGI PMID:25074919 NCBI chr 1:46,846,704...46,964,952
Ensembl chr 1:46,846,704...46,932,012 		JBrowse link
G Tcf3 transcription factor 3 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr10:80,245,375...80,269,814
Ensembl chr10:80,245,348...80,269,481 		JBrowse link
G Tfrc transferrin receptor involved_in IDA
ISO		 (MGI:5775517|PMID:26642240) UniProt
MGI		 PMID:26642240 GO_REF:0000119 MGI:4834177 MGI:5775517 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within IMP (PMID:12855817) MGI PMID:12855817 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786 		JBrowse link
G Tirap toll-interleukin 1 receptor (TIR) domain-containing adaptor protein involved_in IMP (MGI:3531416|PMID:12447442) BHF-UCL PMID:12447442 MGI:3531416 NCBI chr 9:35,095,687...35,111,587
Ensembl chr 9:35,095,847...35,111,587 		JBrowse link
G Tlr4 toll-like receptor 4 acts_upstream_of_or_within IMP (PMID:10549626) MGI PMID:10549626 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521 		JBrowse link
G Tlr9 toll-like receptor 9 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 9:106,099,797...106,104,075
Ensembl chr 9:106,099,797...106,104,082 		JBrowse link
G Tnfrsf13c tumor necrosis factor receptor superfamily, member 13c involved_in
acts_upstream_of_or_within		 IBA
IDA		 (PMID:15240667) GO_Central
MGI		 PMID:15240667 GO_REF:0000033 NCBI chr15:82,105,943...82,108,581
Ensembl chr15:82,105,944...82,108,570 		JBrowse link
G Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 involved_in IMP (MGI:74350|PMID:7749983) BHF-UCL PMID:7749983 MGI:74350 NCBI chr 4:156,098,049...156,101,070
Ensembl chr 4:156,098,300...156,101,069 		JBrowse link
G Tnfsf13b tumor necrosis factor (ligand) superfamily, member 13b involved_in
acts_upstream_of_or_within		 ISO
IDA
IBA		 (PMID:15240667) MGI
GO_Central		 PMID:15240667 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 8:10,056,637...10,086,000
Ensembl chr 8:10,056,467...10,089,072 		JBrowse link
G Vav3 vav 3 oncogene involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:109,247,757...109,593,010
Ensembl chr 3:109,247,969...109,593,014 		JBrowse link
G Wnt3a wingless-type MMTV integration site family, member 3A acts_upstream_of_or_within IDA (PMID:10933391) MGI PMID:10933391 NCBI chr11:59,138,859...59,181,579
Ensembl chr11:59,138,859...59,181,578 		JBrowse link
positive regulation of interleukin-4-dependent isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 involved_in IMP (MGI:3763508|PMID:12496423) BHF-UCL PMID:12496423 MGI:3763508 NCBI chr 1:161,223,009...161,245,777
Ensembl chr 1:161,222,980...161,245,981 		JBrowse link
positive regulation of isotype switching term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Exosc3 exosome component 3 acts_upstream_of_or_within IMP (PMID:21255825) MGI PMID:21255825 NCBI chr 4:45,316,613...45,320,616
Ensembl chr 4:45,316,613...45,342,732 		JBrowse link
G Exosc6 exosome component 6 acts_upstream_of_or_within IMP (PMID:21255825) MGI PMID:21255825 NCBI chr 8:111,782,971...111,784,296
Ensembl chr 8:111,782,971...111,784,296 		JBrowse link
G Hmces 5-hydroxymethylcytosine (hmC) binding, ES cell specific involved_in IDA (MGI:6393148|PMID:31806351) UniProt PMID:31806351 MGI:6393148 NCBI chr 6:87,890,889...87,913,603
Ensembl chr 6:87,890,917...87,913,611 		JBrowse link
G Kmt5b lysine methyltransferase 5B involved_in IMP (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr19:3,816,436...3,868,303
Ensembl chr19:3,817,421...3,868,303 		JBrowse link
G Kmt5c lysine methyltransferase 5C involved_in IMP (MGI:6370097|PMID:28114273) UniProt PMID:28114273 MGI:6370097 NCBI chr 7:4,743,091...4,750,513
Ensembl chr 7:4,743,114...4,750,513 		JBrowse link
G Mad2l2 MAD2 mitotic arrest deficient-like 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 4:148,214,615...148,230,161
Ensembl chr 4:148,214,841...148,230,156 		JBrowse link
G Paxip1 PAX interacting (with transcription-activation domain) protein 1 involved_in IMP (MGI:4821506|PMID:20671152) UniProt PMID:20671152 MGI:4821506 NCBI chr 5:27,947,044...27,999,326
Ensembl chr 5:27,945,078...27,996,689 		JBrowse link
G Rif1 replication timing regulatory factor 1 involved_in IMP (MGI:5468036|PMID:23306439), (MGI:5476381|PMID:23333305), (MGI:5490831|PMID:23333306) UniProt PMID:23306439 PMID:23333305 PMID:23333306 MGI:5468036 MGI:5476381 MGI:5490831 NCBI chr 2:51,962,725...52,016,781
Ensembl chr 2:51,962,844...52,012,395 		JBrowse link
G Shld1 shieldin complex subunit 1 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:132,528,871...132,592,975
Ensembl chr 2:132,528,851...132,592,975 		JBrowse link
G Shld2 shieldin complex subunit 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr14:33,958,905...34,032,528
Ensembl chr14:33,958,990...34,032,450 		JBrowse link
G Shld3 shieldin complex subunit 3 involved_in ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr13:104,310,228...104,314,967
Ensembl chr13:104,310,230...104,314,947 		JBrowse link
G Tfrc transferrin receptor involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:32,427,714...32,451,612
Ensembl chr16:32,427,738...32,451,612 		JBrowse link
G Trp53bp1 transformation related protein 53 binding protein 1 involved_in IMP
ISO		 (MGI:3041657|PMID:15077110), (MGI:3046005|PMID:15159415) UniProt
MGI		 PMID:15077110 PMID:15159415 GO_REF:0000119 MGI:3041657 MGI:3046005 MGI:4834177 NCBI chr 2:121,025,316...121,126,830
Ensembl chr 2:121,023,762...121,101,888 		JBrowse link
positive regulation of isotype switching to IgA isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 involved_in IMP (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859 		JBrowse link
G Msh2 mutS homolog 2 involved_in IMP (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 acts_upstream_of_or_within IMP (PMID:23241889) MGI PMID:23241889 NCBI chr 5:33,974,286...34,055,310
Ensembl chr 5:33,978,069...34,055,319 		JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component involved_in IGI
IMP		 (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of_or_within ISO (PMID:14988498) MGI PMID:14988498 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502 		JBrowse link
G Tnfsf13 tumor necrosis factor (ligand) superfamily, member 13 involved_in
acts_upstream_of_or_within		 IBA
ISO
IMP		 (PMID:14988498) GO_Central
MGI		 PMID:14988498 GO_REF:0000033 NCBI chr11:69,573,403...69,576,380
Ensembl chr11:69,573,672...69,576,610 		JBrowse link
positive regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcf1 cardiotrophin-like cytokine factor 1 involved_in IDA (MGI:3777853|PMID:12023368) BHF-UCL PMID:12023368 MGI:3777853 NCBI chr19:4,264,479...4,273,548
Ensembl chr19:4,264,292...4,273,544 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:14988498) MGI PMID:14988498 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 acts_upstream_of_or_within IGI (PMID:10490661) MGI PMID:10490661 NCBI chr10:127,478,855...127,496,856
Ensembl chr10:127,478,855...127,496,826 		JBrowse link
positive regulation of isotype switching to IgG isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atad5 ATPase family, AAA domain containing 5 acts_upstream_of_or_within IMP (PMID:25404367) MGI PMID:25404367 NCBI chr11:79,980,205...80,026,623
Ensembl chr11:79,980,226...80,026,620 		JBrowse link
G Cd28 CD28 antigen acts_upstream_of_or_within IMP (PMID:7688139) MGI PMID:7688139 NCBI chr 1:60,785,547...60,812,521
Ensembl chr 1:60,755,959...60,812,518 		JBrowse link
G Cd40 CD40 antigen acts_upstream_of_or_within IDA (PMID:12882831) MGI PMID:12882831 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868 		JBrowse link
G Ifng interferon gamma acts_upstream_of_or_within IDA (PMID:12882831) MGI PMID:12882831 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797 		JBrowse link
G Il2 interleukin 2 acts_upstream_of_or_within IMP (PMID:1830926) MGI PMID:1830926 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IDA (PMID:12882831), (PMID:14988498) MGI PMID:12882831 PMID:14988498 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Mlh1 mutL homolog 1 involved_in IMP (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 9:111,057,296...111,100,854
Ensembl chr 9:111,057,296...111,100,859 		JBrowse link
G Msh2 mutS homolog 2 involved_in IMP (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr17:87,979,960...88,031,141
Ensembl chr17:87,979,758...88,031,141 		JBrowse link
G Pagr1a PAXIP1 associated glutamate rich protein 1A involved_in IMP (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chr 7:126,614,223...126,616,524
Ensembl chr 7:126,614,205...126,616,524
Ensembl chr 7:126,614,205...126,616,524 		JBrowse link
G Paxip1 PAX interacting (with transcription-activation domain) protein 1 involved_in IMP (MGI:5752090|PMID:26744420) UniProt PMID:26744420 MGI:5752090 NCBI chr 5:27,947,044...27,999,326
Ensembl chr 5:27,945,078...27,996,689 		JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component involved_in IMP
IGI		 (MGI:1342394|PMID:10430621) CAFA PMID:10430621 MGI:1342394 NCBI chr 5:143,846,379...143,922,538
Ensembl chr 5:143,846,782...143,870,786
Ensembl chr 5:143,846,782...143,870,786 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within IMP (PMID:9015183) MGI PMID:9015183 NCBI chr 1:137,990,601...138,103,491
Ensembl chr 1:137,990,599...138,103,446 		JBrowse link
G Tbx21 T-box 21 acts_upstream_of_or_within IMP (PMID:12882831) MGI PMID:12882831 NCBI chr11:96,988,833...97,006,157
Ensembl chr11:96,988,897...97,006,157 		JBrowse link
positive regulation of plasma cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il10 interleukin 10 acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711 		JBrowse link
G Il2 interleukin 2 acts_upstream_of ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108 		JBrowse link
G Xbp1 X-box binding protein 1 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28576
    immune system process 3142
      leukocyte activation 1139
        lymphocyte activation 931
          B cell activation 324
            positive regulation of B cell activation 95
              B cell costimulation 4
              positive regulation of B cell differentiation + 19
              positive regulation of B cell proliferation 50
              positive regulation of isotype switching + 31
Path 2
Term Annotations click to browse term
  biological_process 28576
    biological regulation 13125
      regulation of biological process 12730
        regulation of multicellular organismal process 3535
          positive regulation of multicellular organismal process 1998
            positive regulation of cell activation 416
              positive regulation of leukocyte activation 392
                positive regulation of lymphocyte activation 354
                  positive regulation of B cell activation 95
                    B cell costimulation 4
                    positive regulation of B cell differentiation + 19
                    positive regulation of B cell proliferation 50
                    positive regulation of isotype switching + 31
paths to the root