Il2rg (interleukin 2 receptor, gamma chain) - Rat Genome Database

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Gene: Il2rg (interleukin 2 receptor, gamma chain) Mus musculus
Analyze
Symbol: Il2rg
Name: interleukin 2 receptor, gamma chain
RGD ID: 731534
MGI Page MGI
Description: Enables interleukin-2 binding activity. Acts upstream of or within positive regulation of gene expression and positive regulation of lymphocyte differentiation. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in X-linked severe combined immunodeficiency; combined T cell and B cell immunodeficiency; and severe combined immunodeficiency. Orthologous to human IL2RG (interleukin 2 receptor subunit gamma).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: [g]c; CD132; common cytokine receptor gamma chain; common cytokine receptor gamma chain variant b; common gamma chain; cytokine receptor common subunit gamma; gamm; gamma C receptor; gamma(; gamma(c); gammaC; gc; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; interleukin-2 receptor subunit gamma; p64
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,307,991 - 100,311,861 (-)NCBIGRCm39mm39
GRCm39 EnsemblX100,307,984 - 100,311,861 (-)Ensembl
GRCm38X101,264,385 - 101,268,255 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,264,378 - 101,268,255 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X98,459,726 - 98,463,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X97,467,106 - 97,470,925 (-)NCBImm8
CeleraX88,180,558 - 88,184,377 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX43.9NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adaptive immunity  (IAGP)
abnormal alpha-beta intraepithelial T cell morphology  (IAGP)
abnormal B cell number  (IAGP)
abnormal basophil physiology  (IAGP)
abnormal CD4-positive, alpha beta T cell morphology  (IAGP)
abnormal cecum morphology  (IAGP)
abnormal cell-mediated immunity  (IAGP)
abnormal class switch recombination  (IAGP)
abnormal decidua basalis morphology  (IAGP)
abnormal dendritic cell physiology  (IAGP)
abnormal estrous cycle  (IAGP)
abnormal gamma-delta T cell differentiation  (IAGP)
abnormal glucose homeostasis  (IAGP)
abnormal gut-associated lymphoid tissue morphology  (IAGP)
abnormal hematopoietic system morphology/development  (IAGP)
abnormal immune serum protein physiology  (IAGP)
abnormal immune system cell morphology  (IAGP)
abnormal immune system organ morphology  (IAGP)
abnormal immune system physiology  (IAGP)
abnormal immunoglobulin level  (IAGP)
abnormal innate immunity  (IAGP)
abnormal interferon secretion  (IAGP)
abnormal interleukin secretion  (IAGP)
abnormal leukocyte morphology  (IAGP)
abnormal lymphocyte morphology  (IAGP)
abnormal mast cell physiology  (IAGP)
abnormal maternal decidual layer morphology  (IAGP)
abnormal mesenteric lymph node morphology  (IAGP)
abnormal myelopoiesis  (IAGP)
abnormal placenta metrial gland morphology  (IAGP)
abnormal proerythroblast morphology  (IAGP)
abnormal response to transplant  (IAGP)
abnormal spleen B cell follicle morphology  (IAGP)
abnormal spleen morphology  (IAGP)
abnormal splenic cell ratio  (IAGP)
abnormal thymocyte activation  (IAGP)
abnormal thymus morphology  (IAGP)
absent B cells  (IAGP)
absent gamma-delta intraepithelial T cell  (IAGP)
absent gamma-delta T cells  (IAGP)
absent NK cells  (IAGP)
absent NK T cells  (IAGP)
absent peripheral lymph nodes  (IAGP)
absent Peyer's patches  (IAGP)
absent spleen germinal center  (IAGP)
absent spleen white pulp  (IAGP)
absent T cells  (IAGP)
absent thymus cortex  (IAGP)
absent thymus medulla  (IAGP)
absent uterine NK cells  (IAGP)
arrested B cell differentiation  (IAGP)
arrested T cell differentiation  (IAGP)
cecum inflammation  (IAGP)
decreased CD4-positive, alpha beta T cell number  (IAGP)
decreased CD8-positive, alpha-beta T cell number  (IAGP)
decreased double-negative T cell number  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased IgE level  (IAGP)
decreased IgG level  (IAGP)
decreased IgG3 level  (IAGP)
decreased IgM level  (IAGP)
decreased immature B cell number  (IAGP)
decreased immunoglobulin level  (IAGP)
decreased incidence of tumors by ionizing radiation induction  (IAGP)
decreased interferon-gamma secretion  (IAGP)
decreased interleukin-2 secretion  (IAGP)
decreased interleukin-4 secretion  (IAGP)
decreased leukocyte cell number  (IAGP)
decreased lymphocyte cell number  (IAGP)
decreased macrophage cell number  (IAGP)
decreased mature B cell number  (IAGP)
decreased mean corpuscular volume  (IAGP)
decreased myeloid dendritic cell number  (IAGP)
decreased NK cell number  (IAGP)
decreased NK T cell number  (IAGP)
decreased plasma cell number  (IAGP)
decreased pre-B cell number  (IAGP)
decreased regulatory T cell number  (IAGP)
decreased single-positive T cell number  (IAGP)
decreased spleen white pulp amount  (IAGP)
decreased splenocyte number  (IAGP)
decreased susceptibility to graft versus host disease  (IAGP)
decreased T cell number  (IAGP)
decreased T cell proliferation  (IAGP)
decreased thymocyte number  (IAGP)
enlarged Peyer's patches  (IAGP)
enlarged spleen  (IAGP)
hyperglycemia  (IAGP)
impaired natural killer cell mediated cytotoxicity  (IAGP)
increased activated T cell number  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased cellular sensitivity to X-ray irradiation  (IAGP)
increased macrophage cell number  (IAGP)
increased megakaryocyte cell number  (IAGP)
increased monocyte cell number  (IAGP)
increased neutrophil cell number  (IAGP)
increased sensitivity to induced morbidity/mortality  (IAGP)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to Retroviridae infection  (IAGP)
lung inflammation  (IAGP)
lymph node hypoplasia  (IAGP)
no abnormal phenotype detected  (IAGP)
premature death  (IAGP)
prolonged diestrus  (IAGP)
prolonged estrous cycle  (IAGP)
prolonged metestrus  (IAGP)
small lymph nodes  (IAGP)
small thymus  (IAGP)
small thymus cortex  (IAGP)
spleen hyperplasia  (IAGP)
spleen hypoplasia  (IAGP)
thrombocytopenia  (IAGP)
thymus cortex hypoplasia  (IAGP)
thymus cysts  (IAGP)
thymus hyperplasia  (IAGP)
thymus hypoplasia  (IAGP)
References

Additional References at PubMed
PMID:7530740   PMID:7602126   PMID:7621883   PMID:7697543   PMID:7805729   PMID:7831294   PMID:7843221   PMID:8262055   PMID:8266076   PMID:8299698   PMID:8359699   PMID:8378320  
PMID:8503926   PMID:8562967   PMID:8566059   PMID:8626013   PMID:8672241   PMID:8750189   PMID:8797792   PMID:8939573   PMID:9016868   PMID:9075927   PMID:9130655   PMID:9196009  
PMID:9252128   PMID:9306921   PMID:9324354   PMID:9334367   PMID:9366397   PMID:9421796   PMID:9473647   PMID:9521083   PMID:9700464   PMID:9820538   PMID:9827902   PMID:9858510  
PMID:9916699   PMID:9927518   PMID:10072522   PMID:10098325   PMID:10349636   PMID:10386866   PMID:10438908   PMID:10477579   PMID:10485651   PMID:10523604   PMID:10534623   PMID:10570276  
PMID:10611339   PMID:10648413   PMID:10653847   PMID:10657646   PMID:10725718   PMID:10799872   PMID:10898497   PMID:10922068   PMID:10985973   PMID:11042159   PMID:11076861   PMID:11080157  
PMID:11133759   PMID:11160234   PMID:11217851   PMID:11237741   PMID:11413198   PMID:11591775   PMID:11696590   PMID:11702064   PMID:11788580   PMID:11815609   PMID:11854357   PMID:11869689  
PMID:12039914   PMID:12069389   PMID:12077246   PMID:12208884   PMID:12354381   PMID:12384415   PMID:12466851   PMID:12477932   PMID:12496402   PMID:12517949   PMID:12543861   PMID:12586624  
PMID:12634786   PMID:12646651   PMID:12689924   PMID:12707300   PMID:12808452   PMID:12872121   PMID:12960317   PMID:14500690   PMID:14583233   PMID:14688383   PMID:15024050   PMID:15047800  
PMID:15064419   PMID:15128825   PMID:15263024   PMID:15452180   PMID:15489334   PMID:15496469   PMID:15582152   PMID:15585839   PMID:15585852   PMID:15661875   PMID:15767371   PMID:15767447  
PMID:15825075   PMID:15879151   PMID:15894277   PMID:15920010   PMID:15944318   PMID:16020505   PMID:16111637   PMID:16141072   PMID:16141073   PMID:16227984   PMID:16380511   PMID:16410448  
PMID:16418296   PMID:16444265   PMID:16492806   PMID:16517733   PMID:16567391   PMID:16582912   PMID:16602821   PMID:16617337   PMID:16621996   PMID:16818782   PMID:16843267   PMID:16864660  
PMID:16897342   PMID:16938836   PMID:16954498   PMID:17016559   PMID:17082625   PMID:17114461   PMID:17182565   PMID:17195845   PMID:17198880   PMID:17222572   PMID:17259968   PMID:17327401  
PMID:17339464   PMID:17371960   PMID:17379078   PMID:17404256   PMID:17404284   PMID:17442930   PMID:17470640   PMID:17509909   PMID:17664939   PMID:17681665   PMID:17683114   PMID:17855567  
PMID:17923504   PMID:17923506   PMID:17923507   PMID:17940219   PMID:17948264   PMID:17948268   PMID:18182587   PMID:18204461   PMID:18227350   PMID:18268321   PMID:18304352   PMID:18345353  
PMID:18371405   PMID:18390713   PMID:18453623   PMID:18463357   PMID:18491294   PMID:18551134   PMID:18563383   PMID:18566388   PMID:18684967   PMID:18688847   PMID:18691745   PMID:18785974  
PMID:18799693   PMID:18852293   PMID:18958875   PMID:18974303   PMID:19006696   PMID:19029903   PMID:19050235   PMID:19052619   PMID:19084435   PMID:19100701   PMID:19109149   PMID:19114665  
PMID:19136960   PMID:19155493   PMID:19203997   PMID:19324903   PMID:19369639   PMID:19447681   PMID:19481135   PMID:19487422   PMID:19528538   PMID:19535452   PMID:19536265   PMID:19593768  
PMID:19636062   PMID:19648279   PMID:19656896   PMID:19659776   PMID:19802382   PMID:19805087   PMID:19841075   PMID:19843883   PMID:19843944   PMID:19846871   PMID:19995948   PMID:20016601  
PMID:20023630   PMID:20068223   PMID:20072130   PMID:20156973   PMID:20190135   PMID:20207995   PMID:20223920   PMID:20231378   PMID:20382848   PMID:20404133   PMID:20421450   PMID:20430958  
PMID:20438766   PMID:20439728   PMID:20439914   PMID:20457870   PMID:20457904   PMID:20472832   PMID:20478526   PMID:20483732   PMID:20488796   PMID:20495069   PMID:20497957   PMID:20505160  
PMID:20530793   PMID:20534524   PMID:20538758   PMID:20562261   PMID:20570944   PMID:20584765   PMID:20592278   PMID:20601939   PMID:20615947   PMID:20630950   PMID:20634377   PMID:20668064  
PMID:20668220   PMID:20671122   PMID:20671189   PMID:20686503   PMID:20688981   PMID:20690177   PMID:20691153   PMID:20713716   PMID:20729912   PMID:20800645   PMID:20805496   PMID:20823234  
PMID:20844537   PMID:20847202   PMID:20935648   PMID:20940318   PMID:20951970   PMID:20972432   PMID:21076046   PMID:21155807   PMID:21209895   PMID:21238430   PMID:21252091   PMID:21262803  
PMID:21262827   PMID:21266536   PMID:21368761   PMID:21393506   PMID:21429805   PMID:21444793   PMID:21460206   PMID:21502498   PMID:21512274   PMID:21518784   PMID:21521873   PMID:21536497  
PMID:21559522   PMID:21576823   PMID:21585397   PMID:21593192   PMID:21604259   PMID:21611197   PMID:21622646   PMID:21624939   PMID:21652674   PMID:21695116   PMID:21724588   PMID:21746927  
PMID:21788504   PMID:21788509   PMID:21791433   PMID:21859956   PMID:21873530   PMID:21873635   PMID:21875955   PMID:21878673   PMID:21926352   PMID:21926555   PMID:21983833   PMID:21985373  
PMID:21993848   PMID:22013038   PMID:22048767   PMID:22065769   PMID:22072769   PMID:22124110   PMID:22227963   PMID:22238321   PMID:22246028   PMID:22278120   PMID:22279057   PMID:22284677  
PMID:22306295   PMID:22340590   PMID:22340598   PMID:22343031   PMID:22366456   PMID:22371883   PMID:22374983   PMID:22392992   PMID:22406538   PMID:22430210   PMID:22464800   PMID:22542847  
PMID:22546855   PMID:22558161   PMID:22566629   PMID:22569301   PMID:22593616   PMID:22611244   PMID:22613798   PMID:22617213   PMID:22645657   PMID:22664870   PMID:22727490   PMID:22727957  
PMID:22737248   PMID:22753496   PMID:22771497   PMID:22778389   PMID:22791816   PMID:22822046   PMID:22829596   PMID:22890824   PMID:22897848   PMID:22897850   PMID:22927549   PMID:22937164  
PMID:22957096   PMID:22972921   PMID:23006848   PMID:23018460   PMID:23071255   PMID:23109710   PMID:23223360   PMID:23225891   PMID:23267015   PMID:23287858   PMID:23293079   PMID:23300950  
PMID:23315074   PMID:23334414   PMID:23345426   PMID:23345428   PMID:23345431   PMID:23348745   PMID:23354049   PMID:23376950   PMID:23378057   PMID:23421592   PMID:23430111   PMID:23454765  
PMID:23455676   PMID:23467088   PMID:23469004   PMID:23475576   PMID:23504518   PMID:23530145   PMID:23585480   PMID:23606600   PMID:23643966   PMID:23659714   PMID:23686485   PMID:23690475  
PMID:23690480   PMID:23746651   PMID:23776508   PMID:23833235   PMID:23869841   PMID:23896410   PMID:23897826   PMID:23918385   PMID:23925295   PMID:23926303   PMID:23933255   PMID:23940740  
PMID:23956433   PMID:23965627   PMID:23975040   PMID:23990961   PMID:24021673   PMID:24040401   PMID:24058178   PMID:24152792   PMID:24209604   PMID:24223822   PMID:24227685   PMID:24239285  
PMID:24263804   PMID:24290754   PMID:24315996   PMID:24336249   PMID:24345755   PMID:24356421   PMID:24362892   PMID:24368085   PMID:24419270   PMID:24442439   PMID:24463278   PMID:24465560  
PMID:24469537   PMID:24474774   PMID:24509713   PMID:24516154   PMID:24518294   PMID:24531377   PMID:24550298   PMID:24577131   PMID:24631153   PMID:24631157   PMID:24633240   PMID:24667486  
PMID:24686171   PMID:24715688   PMID:24736457   PMID:24751730   PMID:24778156   PMID:24785297   PMID:24793546   PMID:24797128   PMID:24798995   PMID:24827856   PMID:24828041   PMID:24859528  
PMID:24870234   PMID:24909888   PMID:24954133   PMID:24958849   PMID:24983319   PMID:25008178   PMID:25017720   PMID:25030174   PMID:25109334   PMID:25126792   PMID:25142413   PMID:25143363  
PMID:25143585   PMID:25215485   PMID:25220211   PMID:25310240   PMID:25329668   PMID:25333658   PMID:25336188   PMID:25342715   PMID:25362351   PMID:25415437   PMID:25426555   PMID:25470051  
PMID:25479751   PMID:25524029   PMID:25532725   PMID:25561180   PMID:25601207   PMID:25645357   PMID:25646432   PMID:25683713   PMID:25712342   PMID:25733518   PMID:25769613   PMID:25794782  
PMID:25818301   PMID:25834108   PMID:25838284   PMID:25849135   PMID:25870199   PMID:25902484   PMID:25908435   PMID:25915732   PMID:25939063   PMID:25964370   PMID:25964371   PMID:26039259  
PMID:26113085   PMID:26181057   PMID:26214742   PMID:26276629   PMID:26276631   PMID:26280998   PMID:26286024   PMID:26316789   PMID:26320660   PMID:26321222   PMID:26403887   PMID:26424750  
PMID:26429886   PMID:26439188   PMID:26542681   PMID:26546129   PMID:26569593   PMID:26595887   PMID:26595889   PMID:26603207   PMID:26644351   PMID:26675347   PMID:26675736   PMID:26678340  
PMID:26690701   PMID:26744522   PMID:26752157   PMID:26755706   PMID:26785948   PMID:26787820   PMID:26796361   PMID:26809508   PMID:26831077   PMID:26847546   PMID:26849055   PMID:26863197  
PMID:26879149   PMID:26884167   PMID:26886799   PMID:27064285   PMID:27099312   PMID:27139822   PMID:27158907   PMID:27184849   PMID:27197203   PMID:27197263   PMID:27256700   PMID:27292632  
PMID:27300437   PMID:27307565   PMID:27323875   PMID:27373157   PMID:27438770   PMID:27478039   PMID:27496730   PMID:27521341   PMID:27535619   PMID:27545889   PMID:27564380   PMID:27581357  
PMID:27622331   PMID:27634757   PMID:27671674   PMID:27698445   PMID:27699249   PMID:27705792   PMID:27708334   PMID:27723723   PMID:27752043   PMID:27783956   PMID:27856754   PMID:27872496  
PMID:27905395   PMID:28069805   PMID:28077418   PMID:28087712   PMID:28089909   PMID:28108611   PMID:28111009   PMID:28115719   PMID:28264908   PMID:28331303   PMID:28424516   PMID:28426964  
PMID:28512240   PMID:28561023   PMID:28585539   PMID:28591638   PMID:28606987   PMID:28617827   PMID:28665271   PMID:28678791   PMID:28698286   PMID:28715505   PMID:28727820   PMID:28747424  
PMID:28783663   PMID:28783664   PMID:28814715   PMID:28827518   PMID:28844693   PMID:28869974   PMID:28874533   PMID:28945245   PMID:28959975   PMID:28960205   PMID:28963568   PMID:29032169  
PMID:29056343   PMID:29070650   PMID:29136504   PMID:29146734   PMID:29150564   PMID:29150659   PMID:29159199   PMID:29166590   PMID:29183988   PMID:29222435   PMID:29266841   PMID:29287229  
PMID:29290617   PMID:29298866   PMID:29334357   PMID:29361613   PMID:29396470   PMID:29429633   PMID:29446074   PMID:29474906   PMID:29496881   PMID:29533787   PMID:29540197   PMID:29549333  
PMID:29551267   PMID:29559473   PMID:29594927   PMID:29624673   PMID:29700358   PMID:29719266   PMID:29720662   PMID:29725010   PMID:29858012   PMID:29861285   PMID:29894694   PMID:29910151  
PMID:29915428   PMID:29925696   PMID:29942093   PMID:29950446   PMID:29975766   PMID:30010246   PMID:30021144   PMID:30049704   PMID:30134157   PMID:30154103   PMID:30174304   PMID:30352428  
PMID:30383447   PMID:30487575   PMID:30504915   PMID:30540841   PMID:30590049   PMID:30651344   PMID:30664659   PMID:30679796   PMID:30720218   PMID:30800133   PMID:30883740   PMID:30888052  
PMID:30894377   PMID:30936486   PMID:30943405   PMID:31091443   PMID:31103381   PMID:31127091   PMID:31160568   PMID:31171792   PMID:31185213   PMID:31230747   PMID:31269440   PMID:31341106  
PMID:31353223   PMID:31371796   PMID:31375314   PMID:31378988   PMID:31415243   PMID:31434684   PMID:31515941   PMID:31534216   PMID:31537642   PMID:31558757   PMID:31609965   PMID:31672934  
PMID:31745215   PMID:31758089   PMID:31772172   PMID:31810881   PMID:31852888   PMID:31873294   PMID:31913286   PMID:31915293   PMID:31982409   PMID:32075728   PMID:32101749   PMID:32213588  
PMID:32381589   PMID:32424282   PMID:32484802   PMID:32522871   PMID:32632165   PMID:32730753   PMID:32735605   PMID:32763164   PMID:32768387   PMID:32814902   PMID:32817334   PMID:32817844  
PMID:32884084   PMID:32949466   PMID:32968282   PMID:33027513   PMID:33087935   PMID:33097708   PMID:33125370   PMID:33295943   PMID:33428661   PMID:33536623   PMID:33951431   PMID:34010296  
PMID:34133926  


Genomics

Comparative Map Data
Il2rg
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X100,307,991 - 100,311,861 (-)NCBIGRCm39mm39
GRCm39 EnsemblX100,307,984 - 100,311,861 (-)Ensembl
GRCm38X101,264,385 - 101,268,255 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX101,264,378 - 101,268,255 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X98,459,726 - 98,463,545 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X97,467,106 - 97,470,925 (-)NCBImm8
CeleraX88,180,558 - 88,184,377 (-)NCBICelera
Cytogenetic MapXDNCBI
cM MapX43.9NCBI
IL2RG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX71,107,404 - 71,112,108 (-)EnsemblGRCh38hg38GRCh38
GRCh38X71,107,404 - 71,111,577 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X70,327,254 - 70,331,427 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X70,243,984 - 70,248,128 (-)NCBINCBI36hg18NCBI36
Build 34X70,110,279 - 70,114,424NCBI
CeleraX70,681,159 - 70,685,386 (-)NCBI
Cytogenetic MapXq13.1NCBI
HuRefX64,146,973 - 64,150,762 (-)NCBIHuRef
CHM1_1X70,219,589 - 70,223,820 (-)NCBICHM1_1
Il2rg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X66,395,330 - 66,399,026 (-)NCBImRatBN7.2
Rnor_6.0 EnsemblX71,162,585 - 71,169,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X71,165,378 - 71,169,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X72,017,856 - 72,021,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,342,055 - 89,345,715 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X89,416,495 - 89,419,068 (-)NCBI
CeleraX66,751,239 - 66,754,899 (-)NCBICelera
Cytogenetic MapXq22NCBI
Il2rg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495547510,676,592 - 10,680,565 (-)NCBIChiLan1.0ChiLan1.0
IL2RG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X70,433,355 - 70,437,590 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0X60,375,815 - 60,386,936 (-)NCBIMhudiblu_PPA_v0panPan3
IL2RG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X55,480,846 - 55,488,485 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX55,481,092 - 55,484,751 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX46,308,162 - 46,311,760 (-)NCBI
ROS_Cfam_1.0X56,449,759 - 56,453,658 (-)NCBI
UMICH_Zoey_3.1X54,418,234 - 54,421,830 (-)NCBI
UNSW_CanFamBas_1.0X55,749,655 - 55,753,253 (-)NCBI
UU_Cfam_GSD_1.0X55,676,806 - 55,680,404 (-)NCBI
Dog CytomapXqNCBI
Il2rg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X46,725,215 - 46,728,870 (+)NCBI
SpeTri2.0NW_004936762487,414 - 491,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL2RG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1X57,143,568 - 57,151,242 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X64,674,048 - 64,677,372 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig CytomapXq13NCBI
IL2RG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X60,905,011 - 60,915,723 (-)NCBI
Vero_WHO_p1.0NW_0236660652,765,485 - 2,776,292 (-)NCBI
Il2rg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249031,402,586 - 1,406,554 (-)NCBI

Position Markers
D13565  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,264,730 - 101,264,810UniSTSGRCm38
MGSCv37X98,460,069 - 98,460,149UniSTSGRCm37
CeleraX88,180,901 - 88,180,981UniSTS
Cytogenetic MapXDUniSTS
cM MapX38.0UniSTS
Whitehead/MRC_RHX1117.13UniSTS
U21795  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,264,625 - 101,264,800UniSTSGRCm38
MGSCv37X98,459,964 - 98,460,139UniSTSGRCm37
CeleraX88,180,796 - 88,180,971UniSTS
Cytogenetic MapXDUniSTS
cM MapX38.0UniSTS
Whitehead/MRC_RHX1117.13UniSTS
Whitehead_YACX UniSTS
PMC155645P2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,266,307 - 101,267,016UniSTSGRCm38
MGSCv37X98,461,646 - 98,462,355UniSTSGRCm37
CeleraX88,182,478 - 88,183,187UniSTS
Cytogenetic MapXDUniSTS
cM MapX38.0UniSTS
Il2rg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,264,987 - 101,265,433UniSTSGRCm38
MGSCv37X98,460,326 - 98,460,772UniSTSGRCm37
CeleraX88,181,158 - 88,181,604UniSTS
Cytogenetic MapXDUniSTS
cM MapX38.0UniSTS
Il2rg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,266,264 - 101,267,811UniSTSGRCm38
MGSCv37X98,461,603 - 98,463,150UniSTSGRCm37
CeleraX88,182,435 - 88,183,982UniSTS
Cytogenetic MapXDUniSTS
Il2rg  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic MapXDUniSTS
U21795  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38X101,264,316 - 101,264,462UniSTSGRCm38
MGSCv37X98,459,655 - 98,459,801UniSTSGRCm37
CeleraX88,180,487 - 88,180,633UniSTS
Cytogenetic MapXDUniSTS
Whitehead/MRC_RHX1117.13UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357433Dbts2_mdiabetes 2 (mouse)Not determinedX7360056151324042Mouse
4141630Gct6_mgranulosa cell tumorigenesis 6 (mouse)Not determined48090244130864007Mouse
13824980Ferq1_mgenetic fertility QTL 1 (mouse)X55000000150000000Mouse
4141665Mhysq2_mmale hybrid sterility QTL 2 (mouse)Not determined72410246140302463Mouse
12879918Shm4_msperm head morphology 4 (mouse)X73028444103019114Mouse
1357500Mdmsc6_mmodifier of muscularity 6 (mouse)Not determinedX76263065110263152Mouse
1302054Gct4_mgranulosa cell tumorigenesis 4 (mouse)Not determinedX77080730103019114Mouse
11075102Modc2_mmodifier of Odc2 (mouse)X81146308115146453Mouse
4141803Lmr30_mleishmaniasis resistance 30 (mouse)Not determined86019000120019114Mouse
13208552Wght12_mweight 12 (mouse)X95000000151000000Mouse
13208556Lgth14_mbody length 14 (mouse)X95000000151000000Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:899
Count of miRNA genes:537
Interacting mature miRNAs:620
Transcripts:ENSMUST00000033664, ENSMUST00000127538, ENSMUST00000135038, ENSMUST00000145074
Prediction methods:Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000033664   ⟹   ENSMUSP00000033664
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 EnsemblX101,264,378 - 101,268,255 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127538
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 EnsemblX101,267,196 - 101,268,158 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135038   ⟹   ENSMUSP00000123318
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 EnsemblX101,264,938 - 101,267,434 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145074
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 EnsemblX101,266,666 - 101,268,190 (-)Ensembl
RefSeq Acc Id: NM_001308535   ⟹   NP_001295464
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X100,307,991 - 100,311,861 (-)NCBI
GRCm38X101,264,385 - 101,268,255 (-)NCBI
Sequence:
RefSeq Acc Id: NM_013563   ⟹   NP_038591
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X100,307,991 - 100,311,861 (-)NCBI
GRCm38X101,264,385 - 101,268,255 (-)NCBI
MGSCv37X98,459,726 - 98,463,545 (-)RGD
CeleraX88,180,558 - 88,184,377 (-)RGD
cM MapX ENTREZGENE
Sequence:
RefSeq Acc Id: XM_017318396   ⟹   XP_017173885
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39X100,308,544 - 100,311,856 (-)NCBI
GRCm38X101,264,387 - 101,268,251 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_038591   ⟸   NM_013563
- Peptide Label: isoform a precursor
- UniProtKB: P34902 (UniProtKB/Swiss-Prot),   Q3UPA9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001295464   ⟸   NM_001308535
- Peptide Label: isoform b precursor
- UniProtKB: Q3UPA9 (UniProtKB/TrEMBL),   V5SIM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173885   ⟸   XM_017318396
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000033664   ⟸   ENSMUST00000033664
RefSeq Acc Id: ENSMUSP00000123318   ⟸   ENSMUST00000135038
Protein Domains
Fibronectin type-III   IL6Ra-bind

Promoters
RGD ID:6845860
Promoter ID:MM_KWN:61304
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung
Transcripts:OTTMUST00000043981
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X98,462,331 - 98,463,372 (-)MPROMDB
RGD ID:6845862
Promoter ID:MM_KWN:61305
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:OTTMUST00000043978,   OTTMUST00000043980,   UC009TXD.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36X98,463,431 - 98,464,162 (-)MPROMDB
RGD ID:13681062
Promoter ID:EPDNEW_M24680
Type:initiation region
Name:Il2rg_1
Description:Mus musculus interleukin 2 receptor, gamma chain , transcriptvariant b, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38X101,268,201 - 101,268,261EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96551 AgrOrtholog
Ensembl Genes ENSMUSG00000031304 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000033664 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000123318 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000033664 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000135038 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hempt_rcpt_S_F1_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TypeI_recpt_CBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16186 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96551 ENTREZGENE
NCBI Gene 16186 ENTREZGENE
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL6Ra-bind UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Il2rg PhenoGen
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMATOPO_REC_S_F1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B0QZX1_MOUSE UniProtKB/TrEMBL
  IL2RG_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3UPA9 ENTREZGENE, UniProtKB/TrEMBL
  V5SIM2 ENTREZGENE, UniProtKB/TrEMBL