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Gene: Ighm (immunoglobulin heavy constant mu) Mus musculus
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Symbol: Ighm
Name: immunoglobulin heavy constant mu
Description: Exhibits several functions, including antigen binding activity; identical protein binding activity; and immunoglobulin receptor binding activity. Involved in several processes, including early endosome to late endosome transport; immunoglobulin mediated immune response; and positive regulation of protein phosphorylation. Localizes to several cellular components, including the B cell receptor complex; external side of plasma membrane; and immunoglobulin complex, circulating. Used to study non-Hodgkin lymphoma and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in agammaglobulinemia. Is expressed in several structures, including brain; hemolymphoid system; and liver. Orthologous to human IGHM (immunoglobulin heavy constant mu); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-methylcholanthrene; 4-hydroxyphenyl retinamide.
Type: gene
RefSeq Status: VALIDATED
Also known as: AI326478; Igh-6; Igh-M; Igh6; Igm; muH
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12113,418,558 - 113,422,730 (-)Ensembl
GRCm3812113,418,826 - 113,422,730 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712114,657,037 - 114,660,941 (-)NCBIGRCm37mm9NCBIm37
Celera12114,605,174 - 114,863,569 (-)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1262.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Ighm
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11303086
Created: 2016-06-28
Species: Mus musculus
Last Modified: 2020-02-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.