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Gene: Inpp5d (inositol polyphosphate-5-phosphatase D) Mus musculus
Symbol: Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Description: Exhibits phosphatase activity and protein domain specific binding activity. Involved in several processes, including negative regulation of B cell proliferation; negative regulation of bone resorption; and regulation of hemopoiesis. Predicted to colocalize with the plasma membrane. Used to study Paget's disease of bone. Is expressed in several structures, including integumental system; nervous system; respiratory system; skeleton; and spleen. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D); PARTICIPATES IN erythropoietin signaling pathway; Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323613; inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145 kDa; MGC117680; p150Ship; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; s-SHIP; SH2 containing inositol phosphotase; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SH2-containing inositol phosphatase SHIP; SHIP; SHIP-1; SHIP1; SIP-145; Src homology 2 domain-containing inositol-5-phosphatase
Homo sapiens (human) : INPP5D (inositol polyphosphate-5-phosphatase D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Inpp5d (inositol polyphosphate-5-phosphatase D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5D (inositol polyphosphate-5-phosphatase D)
Canis lupus familiaris (dog) : INPP5D (inositol polyphosphate-5-phosphatase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Sus scrofa (pig) : INPP5D (inositol polyphosphate-5-phosphatase D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl187,620,312 - 87,720,507 (+)Ensembl
GRCm38187,620,312 - 87,720,510 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37189,516,887 - 89,617,083 (+)NCBIGRCm37mm9NCBIm37
MGSCv36189,451,550 - 89,551,673 (+)NCBImm8
Celera190,584,657 - 90,684,698 (+)NCBICelera
Cytogenetic Map1 DNCBI
cM Map144.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Inpp5d
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551628
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.