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Gene: Inpp5d (inositol polyphosphate-5-phosphatase D) Mus musculus
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Symbol: Inpp5d
Name: inositol polyphosphate-5-phosphatase D
Description: Exhibits phosphatase activity and protein domain specific binding activity. Involved in several processes, including negative regulation of B cell proliferation; negative regulation of bone resorption; and regulation of hemopoiesis. Predicted to colocalize with the plasma membrane. Used to study Paget's disease of bone. Is expressed in several structures, including integumental system; nervous system; respiratory system; skeleton; and spleen. Orthologous to human INPP5D (inositol polyphosphate-5-phosphatase D); PARTICIPATES IN erythropoietin signaling pathway; Fc epsilon receptor mediated signaling pathway; granulocyte-macrophage colony-stimulating factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI323613; inositol polyphosphate-5-phosphatase of 145 kDa; inositol polyphosphate-5-phosphatase, 145 kDa; MGC117680; p150Ship; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; phosphatidylinositol-4,5-bisphosphate 5-phosphatase; s-SHIP; SH2 containing inositol phosphotase; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SH2 domain-containing inositol-5'-phosphatase 1; SH2-containing inositol phosphatase SHIP; SHIP; SHIP-1; SHIP1; SIP-145; Src homology 2 domain-containing inositol-5-phosphatase
Orthologs:
Homo sapiens (human) : INPP5D (inositol polyphosphate-5-phosphatase D)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Inpp5d (inositol polyphosphate-5-phosphatase D)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Pan paniscus (bonobo/pygmy chimpanzee) : INPP5D (inositol polyphosphate-5-phosphatase D)
Canis lupus familiaris (dog) : INPP5D (inositol polyphosphate-5-phosphatase D)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Inpp5d (inositol polyphosphate-5-phosphatase D)
Sus scrofa (pig) : INPP5D (inositol polyphosphate-5-phosphatase D)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl187,620,312 - 87,720,507 (+)Ensembl
GRCm38187,620,312 - 87,720,510 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37189,516,887 - 89,617,083 (+)NCBIGRCm37mm9NCBIm37
MGSCv36189,451,550 - 89,551,673 (+)NCBImm8
Celera190,584,657 - 90,684,698 (+)NCBICelera
Cytogenetic Map1 DNCBI
cM Map144.44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Inpp5d
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551628
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.