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Gene: Ticam1 (toll-like receptor adaptor molecule 1) Mus musculus
Symbol: Ticam1
Name: toll-like receptor adaptor molecule 1
Description: Predicted to have protein kinase binding activity. Involved in several processes, including positive regulation of cellular metabolic process; positive regulation of cytokine production; and positive regulation of lymphocyte activation. Localizes to the cytosol and mitochondrion. Human ortholog(s) of this gene implicated in brain disease. Is expressed in genitourinary system. Orthologous to human TICAM1 (toll like receptor adaptor molecule 1); PARTICIPATES IN Toll-like receptor signaling pathway; Chagas disease pathway; hepatitis C pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; alpha-D-galactose; auranofin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW046014; AW547018; TICAM-1; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; TIR domain-containing adaptor inducing interferon-beta; toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta; toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; TRIF
Homo sapiens (human) : TICAM1 (toll like receptor adaptor molecule 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ticam1 (toll-like receptor adaptor molecule 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ticam1 (toll like receptor adaptor molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TICAM1 (toll like receptor adaptor molecule 1)
Canis lupus familiaris (dog) : TICAM1 (toll like receptor adaptor molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ticam1 (toll like receptor adaptor molecule 1)
Sus scrofa (pig) : TICAM1 (toll like receptor adaptor molecule 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm381756,269,462 - 56,276,767 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371756,408,885 - 56,416,190 (-)NCBIGRCm37mm9NCBIm37
MGSCv361755,903,171 - 55,910,412 (-)NCBImm8
MGSCv361755,328,736 - 55,335,977 (-)NCBImm8
Cytogenetic Map17 DNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ticam1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1557557
Created: 2005-11-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.