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Gene: Stat6 (signal transducer and activator of transcription 6) Mus musculus
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Symbol: Stat6
Name: signal transducer and activator of transcription 6
Description: Exhibits RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in several processes, including T-helper 1 cell lineage commitment; mammary gland development; and regulation of nucleobase-containing compound metabolic process. Localizes to the cytoplasm and nuclear chromatin. Human ortholog(s) of this gene implicated in lipoid nephrosis; prostate carcinoma; and urinary schistosomiasis. Is expressed in several structures, including 2-cell stage embryo; alimentary system; lower urinary tract; male reproductive system; and olfactory epithelium. Orthologous to human STAT6 (signal transducer and activator of transcription 6); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-4 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 1,4-dithiothreitol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: signal transducer and transcription activator 6
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl10127,642,986 - 127,660,957 (+)Ensembl
GRCm3810127,642,955 - 127,660,987 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710127,080,042 - 127,098,043 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610127,046,120 - 127,063,352 (+)NCBImm8
Celera10130,035,284 - 130,053,348 (+)NCBICelera
Cytogenetic Map10 D3NCBI
cM Map1074.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Stat6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319195
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.