Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Cd81 (CD81 antigen) Mus musculus
Analyze
Symbol: Cd81
Name: CD81 antigen
Description: Predicted to have cholesterol binding activity; signaling receptor binding activity; and virus receptor activity. Involved in several processes, including cellular response to low-density lipoprotein particle stimulus; positive regulation of immune response; and syncytium formation by plasma membrane fusion. Localizes to the membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; nervous system; and sensory organ. Orthologous to human CD81 (CD81 molecule); PARTICIPATES IN B cell receptor signaling pathway; hepatitis C pathway; malaria pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 26 kDa cell surface protein TAPA-1; Tapa-1; Tapa1; target of the antiproliferative antibody 1; Tspan28
Orthologs:
Homo sapiens (human) : CD81 (CD81 molecule)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cd81 (Cd81 molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd81 (CD81 molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD81 (CD81 molecule)
Canis lupus familiaris (dog) : CD81 (CD81 molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd81 (CD81 molecule)
Sus scrofa (pig) : CD81 (CD81 molecule)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm387143,052,750 - 143,067,930 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377150,238,655 - 150,253,835 (+)NCBIGRCm37mm9NCBIm37
MGSCv367142,862,185 - 142,877,314 (+)NCBImm8
Celera7142,808,354 - 142,823,535 (+)NCBICelera
Cytogenetic Map7 F5NCBI
cM Map788.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cd81
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731701
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.