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ONTOLOGY REPORT - ANNOTATIONS


Term:(-)-epicatechin
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Accession:CHEBI:90 term browser browse the term
Definition:A catechin with (2R,3R)-configuration.
Synonyms:exact_synonym: (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
 related_synonym: Formula=C15H14O6;   InChI=1S/C15H14O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-5,13,15-20H,6H2/t13-,15-/m1/s1;   InChIKey=PFTAWBLQPZVEMU-UKRRQHHQSA-N;   SMILES=[H][C@@]1(Oc2cc(O)cc(O)c2C[C@H]1O)c1ccc(O)c(O)c1
 alt_id: CHEBI:18484
 xref: CAS:490-46-0;   KEGG:C09727;   KNApSAcK:C00000956;   LINCS:LSM-20956;   LIPID_MAPS_instance:LMPK12020003;   MetaCyc:CPD-7630;   PMID:10427682;   PMID:7655336;   Reaxys:92760
 cyclic_relationship: is_enantiomer_of CHEBI:76125


show annotations for term's descendants       view all columns           Sort by:
 
procyanidin B2 term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Atg12 autophagy related 12 JBrowse link 18 40,721,799 40,732,143 RGD:6480464
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Bcl2l11 BCL2 like 11 JBrowse link 3 120,726,906 120,764,192 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Brca1 BRCA1, DNA repair associated JBrowse link 10 89,394,821 89,455,093 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Dnmt1 DNA methyltransferase 1 JBrowse link 8 21,922,515 21,968,495 RGD:6480464
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:6480464
G Dnmt3b DNA methyltransferase 3 beta JBrowse link 3 149,131,541 149,170,061 RGD:6480464
G Foxo1 forkhead box O1 JBrowse link 2 141,451,234 141,527,016 RGD:6480464
G Gsk3b glycogen synthase kinase 3 beta JBrowse link 11 65,060,884 65,208,842 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Klk7 kallikrein-related peptidase 7 JBrowse link 1 99,749,991 99,754,723 RGD:6480464
G Map1lc3b microtubule-associated protein 1 light chain 3 beta JBrowse link 19 53,635,449 53,643,970 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mfge8 milk fat globule EGF and factor V/VIII domain containing JBrowse link 1 140,845,478 140,860,882 RGD:6480464
G Mir122 microRNA 122 JBrowse link 18 60,755,285 60,755,369 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nphs1 NPHS1 adhesion molecule, nephrin JBrowse link 1 88,922,346 88,950,560 RGD:6480464
G Nphs2 NPHS2 stomatin family member, podocin JBrowse link 13 73,929,136 73,941,522 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 JBrowse link 18 22,964,121 23,047,896 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:6480464
G Serpinb5 serpin family B member 5 JBrowse link 13 26,903,052 26,923,250 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Top2a DNA topoisomerase II alpha JBrowse link 10 86,901,467 86,930,947 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19779
    role 19727
      chemical role 19258
        antioxidant 14222
          (-)-epicatechin 40
            (+)-gallocatechin-(4alpha->8)-(-)-epicatechin 0
            (-)-epicatechin-(4alpha->8)-(-)-epicatechin + 0
            (-)-epicatechin-(4beta->8)-(+)-gallocatechin 0
            (-)-epicatechin-(4beta->8)-(-)-epigallocatechin 0
            (-)-epicatechin-3-O-gallate 0
            (-)-epicatechin-5-gallate 0
            (-)-epigallocatechin-(4beta->8)-(-)-epicatechin 0
            3'-methylepicatechin-7-sulfate 0
            arecatannin B1 0
            epicatechin 3-O-(3'-O-methylgallate) 0
            epicatechin-3'-glucuronide 0
            epigallocatechin-(4beta->8,2beta->O-7)-epicatechin 0
            proanthocyanidin A2 0
            procyanidin B1 + 0
            procyanidin B2 + 40
            procyanidin B4 + 0
            procyanidin B5 0
            procyanidin B8 0
            procyanidin C1 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19779
    subatomic particle 19777
      composite particle 19777
        hadron 19777
          baryon 19777
            nucleon 19777
              atomic nucleus 19777
                atom 19777
                  main group element atom 19664
                    p-block element atom 19664
                      carbon group element atom 19559
                        carbon atom 19548
                          organic molecular entity 19548
                            organic molecule 19472
                              organic cyclic compound 19236
                                organic heterocyclic compound 18361
                                  oxacycle 17134
                                    benzopyran 9494
                                      1-benzopyran 9190
                                        flavonoid 6366
                                          flavans 2977
                                            hydroxyflavan 2849
                                              catechin 2833
                                                (-)-epicatechin 40
                                                  (+)-gallocatechin-(4alpha->8)-(-)-epicatechin 0
                                                  (-)-epicatechin-(4alpha->8)-(-)-epicatechin + 0
                                                  (-)-epicatechin-(4beta->8)-(+)-gallocatechin 0
                                                  (-)-epicatechin-(4beta->8)-(-)-epigallocatechin 0
                                                  (-)-epicatechin-3-O-gallate 0
                                                  (-)-epicatechin-5-gallate 0
                                                  (-)-epigallocatechin-(4beta->8)-(-)-epicatechin 0
                                                  3'-methylepicatechin-7-sulfate 0
                                                  arecatannin B1 0
                                                  epicatechin 3-O-(3'-O-methylgallate) 0
                                                  epicatechin-3'-glucuronide 0
                                                  epigallocatechin-(4beta->8,2beta->O-7)-epicatechin 0
                                                  proanthocyanidin A2 0
                                                  procyanidin B1 + 0
                                                  procyanidin B2 + 40
                                                  procyanidin B4 + 0
                                                  procyanidin B5 0
                                                  procyanidin B8 0
                                                  procyanidin C1 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.