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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:ethylamine
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Accession:CHEBI:15862 term browser browse the term
Definition:A two-carbon primary aliphatic amine.
Synonyms:related_synonym: 1-aminoethane;   ETHANAMINE;   Formula=C2H7N;   InChI=1S/C2H7N/c1-2-3/h2-3H2,1H3;   InChIKey=QUSNBJAOOMFDIB-UHFFFAOYSA-N;   SMILES=CCN;   aminoethane
 alt_id: CHEBI:14228;   CHEBI:23998;   CHEBI:44361;   CHEBI:4897
 xref: Beilstein:505933;   CAS:75-04-7;   Gmelin:897;   HMDB:HMDB0013231;   KEGG:C00797
 xref_mesh: MESH:C041564
 xref: MetaCyc:ETHANAMINE;   PDBeChem:NEH;   PMID:10930630;   PMID:11074065;   Reaxys:505933;   Wikipedia:Ethylamine
 cyclic_relationship: is_conjugate_base_of CHEBI:566789


show annotations for term's descendants           Sort by:
ethylamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with butylbenzyl phthalate co-treated with INS protein] results in increased abundance of ethylamine analog CTD PMID:26820058 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
amifostine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Amifostine co-treated with Doxorubicin] results in increased expression of BAX mRNA CTD PMID:15985719 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Amifostine co-treated with Doxorubicin] results in decreased expression of BCL2 mRNA CTD PMID:15985719 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO [Amifostine co-treated with Doxorubicin] results in increased activity of CASP3 protein; Amifostine inhibits the reaction [Idarubicin results in increased activity of CASP3 protein]; Amifostine promotes the reaction [Idarubicin results in increased activity of CASP3 protein] CTD PMID:15985719 PMID:18438337 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases phosphorylation
multiple interactions		 ISO Amifostine results in decreased phosphorylation of CDK1 protein
olomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]; TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]		 CTD PMID:16628227 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression
increases expression		 ISO Amifostine results in decreased expression of CDKN1A mRNA
Amifostine results in increased expression of CDKN1A protein		 CTD PMID:12618886 PMID:14555708 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Ei24 EI24, autophagy associated transmembrane protein decreases expression ISO Amifostine results in decreased expression of EI24 mRNA CTD PMID:14555708 NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO Amifostine inhibits the reaction [IL6 protein results in increased phosphorylation of MYL2 protein] CTD PMID:19010997 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of and results in increased phosphorylation of MAPK14 protein] CTD PMID:19010997 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Amifostine results in decreased expression of MDM2 mRNA CTD PMID:14555708 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased activity of MPO protein] CTD PMID:19010997 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [Amifostine co-treated with TP53] results in increased expression of MYC mRNA CTD PMID:14555708 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myl2 myosin light chain 2 multiple interactions ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MYL2 protein]
Amifostine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MYL2 protein]; Amifostine inhibits the reaction [IL6 protein results in increased phosphorylation of MYL2 protein]		 CTD PMID:19010997 NCBI chr12:34,454,223...34,468,554
Ensembl chr12:34,454,218...34,468,983 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression
multiple interactions		 ISO Amifostine results in decreased expression of NFKBIA protein
Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]		 CTD PMID:10590050 PMID:19010997 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Amifostine inhibits the reaction [Benzene results in decreased expression of PCNA protein] CTD PMID:17661222 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases localization		 ISO Amifostine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]
Amifostine results in increased localization of RELA protein		 CTD PMID:10590050 PMID:19010997 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
affects response to substance
increases activity		 ISO [Amifostine co-treated with TP53] results in increased expression of MYC mRNA; olomoucine inhibits the reaction [TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]]; TP53 protein promotes the reaction [Amifostine results in decreased phosphorylation of CDK1 protein]
Amifostine results in increased expression of TP53 protein
TP53 affects the susceptibility to Amifostine
Amifostine results in increased activity of TP53 protein		 CTD PMID:12618886 PMID:14555708 PMID:16628227 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 decreases expression ISO Amifostine results in decreased expression of TP53I3 mRNA CTD PMID:14555708 NCBI chr 6:27,818,327...27,825,753 JBrowse link
cystamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:17708605 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:17708605 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein] CTD PMID:17708605 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17708605 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
cysteamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipor2 adiponectin receptor 2 increases expression EXP dietary cysteamine increases expression of adipor2 mRNA in soleus muscle and retroperitoneal adipose tissue RGD PMID:17696487 RGD:21079417 NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355 		JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions		 EXP Cysteamine results in increased expression of CTSD protein
Omeprazole inhibits the reaction [Cysteamine results in increased expression of CTSD protein]; thamira parpam inhibits the reaction [Cysteamine results in increased expression of CTSD protein]		 CTD PMID:20165931 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases activity EXP Cysteamine results in increased activity of CYP7A1 protein CTD PMID:1175606 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases activity
multiple interactions		 ISO Cysteamine results in decreased activity of GCLC protein
[Cysteamine results in decreased activity of GCLC protein] which results in decreased abundance of Glutathione		 CTD PMID:15282320 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide decreases expression
multiple interactions		 EXP Cysteamine results in decreased expression of GHRL mRNA; Cysteamine results in decreased expression of GHRL protein
Cysteamine results in increased expression of and results in increased secretion of GHRL protein		 CTD PMID:15778430 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 EXP [Cysteamine results in increased expression of HMOX1] which results in increased expression of SOD2; Cysteamine results in increased expression of HMOX1 mRNA; Cysteamine results in increased expression of HMOX1 protein
[stannous mesoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Cysteamine results in increased expression of SOD2 protein]		 CTD PMID:10942521 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Mmp12 matrix metallopeptidase 12 increases expression ISO Cysteamine results in increased expression of MMP12 mRNA; Cysteamine results in increased expression of MMP12 protein CTD PMID:22532830 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Cysteamine results in increased expression of MMP14 mRNA; Cysteamine results in increased expression of MMP14 protein CTD PMID:22532830 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
multiple interactions
increases expression		 ISO Cysteamine results in decreased activity of MMP9 protein
Cysteamine results in increased expression of and results in decreased activity of MMP9 protein
Cysteamine results in increased expression of MMP9 mRNA		 CTD PMID:22532830 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression		 EXP geraniol inhibits the reaction [Cysteamine results in increased expression of MPO protein]; Omeprazole inhibits the reaction [Cysteamine results in increased expression of MPO protein]; thamira parpam inhibits the reaction [Cysteamine results in increased expression of MPO protein] CTD PMID:20165931 PMID:24337826 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions		 EXP [Cysteamine results in increased expression of HMOX1] which results in increased expression of SOD2; Cysteamine results in increased expression of SOD2 mRNA; Cysteamine results in increased expression of SOD2 protein
[stannous mesoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [Cysteamine results in increased expression of SOD2 protein]		 CTD PMID:10942521 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sst somatostatin decreases expression EXP Cysteamine results in decreased expression of SST protein CTD PMID:15778430 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Vnn1 vanin 1 increases chemical synthesis
multiple interactions		 ISO VNN1 results in increased chemical synthesis of Cysteamine
Cysteamine inhibits the reaction [VNN1 gene mutant form results in decreased susceptibility to Paraquat]		 CTD PMID:11042271 PMID:15282320 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395 		JBrowse link
N-acetylcysteamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor decreases phosphorylation ISO 2-acetamidoethanethiol analog results in decreased phosphorylation of EGFR protein CTD PMID:20058253 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO 2-acetamidoethanethiol analog results in decreased activity of and results in decreased phosphorylation of ERBB2 protein CTD PMID:20058253 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases phosphorylation ISO 2-acetamidoethanethiol analog results in decreased phosphorylation of ERBB3 protein CTD PMID:20058253 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
sulfluramid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO sulfluramid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO sulfluramid results in increased expression of ACOT2 mRNA CTD PMID:35337807 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO sulfluramid results in increased expression of CYP2B6 mRNA CTD PMID:35337807 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO sulfluramid results in increased expression of CYP7A1 mRNA CTD PMID:35337807 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO sulfluramid results in increased expression of EHHADH mRNA CTD PMID:35337807 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Fasn fatty acid synthase increases expression ISO sulfluramid results in increased expression of FASN mRNA CTD PMID:35337807 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO sulfluramid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression ISO sulfluramid results in increased expression of GSTA1 mRNA CTD PMID:35337807 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO sulfluramid results in increased expression of HMGCS1 mRNA CTD PMID:35337807 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO sulfluramid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO sulfluramid results in increased expression of NFE2L2 mRNA CTD PMID:35337807 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO sulfluramid results in increased expression of NQO1 mRNA CTD PMID:35337807 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO sulfluramid results in increased expression of NR1I2 mRNA CTD PMID:35337807 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO sulfluramid results in increased expression of NR1I3 mRNA CTD PMID:35337807 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO sulfluramid results in increased expression of PCK2 mRNA CTD PMID:35337807 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
affects binding		 ISO sulfluramid results in increased expression of PPARA mRNA
sulfluramid binds to PPARA protein		 CTD PMID:35337807 PMID:35752307 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
affects binding		 ISO
EXP		 sulfluramid results in increased expression of PPARG mRNA
sulfluramid binds to PPARG protein		 CTD PMID:35337807 PMID:35752307 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO sulfluramid results in increased expression of SCD mRNA CTD PMID:35337807 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO sulfluramid results in increased expression of SLC27A1 mRNA CTD PMID:35337807 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO sulfluramid results in increased expression of SOD1 mRNA CTD PMID:35337807 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO sulfluramid results in increased expression of SREBF1 mRNA CTD PMID:35337807 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO sulfluramid results in increased expression of SULT2A1 mRNA CTD PMID:35337807 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
WR-1065 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of CAT protein CTD PMID:17388698 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of CCL5 mRNA CTD PMID:12007958 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in decreased expression of GSTP1 mRNA CTD PMID:12007958 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of IL2RA mRNA CTD PMID:12007958 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Myb MYB proto-oncogene, transcription factor increases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of MYB mRNA CTD PMID:12007958 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in decreased expression of MYC mRNA CTD PMID:12007958 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [NFKB1 protein binds to RELA protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11390188 PMID:11917294 PMID:12007958 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [NFKB1 protein binds to RELA protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of [RELA protein binds to NFKB1 protein] CTD PMID:11390188 PMID:11917294 PMID:12007958 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
increases activity
multiple interactions		 ISO N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 mRNA; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 protein
N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2
[TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]; TNFRSF1A protein affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]
helenalin inhibits the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of SOD2 protein]; N-(2-mercaptoethyl)-1,3-diaminopropane results in increased expression of and results in increased activity of SOD2 protein		 CTD PMID:11390188 PMID:11917294 PMID:12007958 PMID:16540396 PMID:17388698 More... NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO [TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2]; TNFRSF1A protein affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2] CTD PMID:21945096 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [TNFRSF1A protein co-treated with TNFRSF1B protein] affects the reaction [N-(2-mercaptoethyl)-1,3-diaminopropane results in increased activity of SOD2] CTD PMID:21945096 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        NMR chemical shift reference compound 17938
          ammonia 17797
            organic amino compound 17797
              amine 8269
                primary amine 6318
                  primary aliphatic amine 188
                    ethylamine 66
                      2-aminoethyl group 0
                      cysteamine + 44
                      sulfluramid 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    main group molecular entity 19756
                      s-block molecular entity 19595
                        hydrogen molecular entity 19582
                          hydrides 19095
                            inorganic hydride 18093
                              pnictogen hydride 18082
                                nitrogen hydride 17989
                                  azane 17798
                                    ammonia 17797
                                      organic amino compound 17797
                                        primary amino compound 9301
                                          primary amine 6318
                                            primary aliphatic amine 188
                                              ethylamine 66
                                                2-aminoethyl group 0
                                                cysteamine + 44
                                                sulfluramid 22
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