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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sulfluramid
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Accession:CHEBI:81945 term browser browse the term
Definition:A sulfonamide obtained by the formal condensation of perfluorooctane-1-sulfonic acid with ethylamine.
Synonyms:exact_synonym: N-ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane-1-sulfonamide
 related_synonym: Formula=C10H6F17NO2S;   InChI=1S/C10H6F17NO2S/c1-2-28-31(29,30)10(26,27)8(21,22)6(17,18)4(13,14)3(11,12)5(15,16)7(19,20)9(23,24)25/h28H,2H2,1H3;   InChIKey=CCEKAJIANROZEO-UHFFFAOYSA-N;   N-Ethylperfluorooctylsulfonamide;   N-ethylperfluorooctane-1-sulfonamide;   SMILES=CCNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
 xref: CAS:4151-50-2;   KEGG:C18766
 xref_mesh: MESH:C063732
 xref: PMID:1495031;   PMID:15713031;   PMID:1673400;   PMID:2324377;   PPDB:602;   Pesticides:sulfluramid;   Reaxys:2317462



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sulfluramid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO sulfluramid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO sulfluramid results in increased expression of ACOT2 mRNA CTD PMID:35337807 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO sulfluramid results in increased expression of CYP2B6 mRNA CTD PMID:35337807 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 increases expression ISO sulfluramid results in increased expression of CYP7A1 mRNA CTD PMID:35337807 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO sulfluramid results in increased expression of EHHADH mRNA CTD PMID:35337807 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Fasn fatty acid synthase increases expression ISO sulfluramid results in increased expression of FASN mRNA CTD PMID:35337807 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO sulfluramid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression ISO sulfluramid results in increased expression of GSTA1 mRNA CTD PMID:35337807 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO sulfluramid results in increased expression of HMGCS1 mRNA CTD PMID:35337807 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO sulfluramid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO sulfluramid results in increased expression of NFE2L2 mRNA CTD PMID:35337807 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO sulfluramid results in increased expression of NQO1 mRNA CTD PMID:35337807 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO sulfluramid results in increased expression of NR1I2 mRNA CTD PMID:35337807 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression ISO sulfluramid results in increased expression of NR1I3 mRNA CTD PMID:35337807 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO sulfluramid results in increased expression of PCK2 mRNA CTD PMID:35337807 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
affects binding
ISO sulfluramid results in increased expression of PPARA mRNA
sulfluramid binds to PPARA protein
CTD PMID:35337807 PMID:35752307 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
affects binding
ISO
EXP
sulfluramid results in increased expression of PPARG mRNA
sulfluramid binds to PPARG protein
CTD PMID:35337807 PMID:35752307 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO sulfluramid results in increased expression of SCD mRNA CTD PMID:35337807 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO sulfluramid results in increased expression of SLC27A1 mRNA CTD PMID:35337807 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Sod1 superoxide dismutase 1 increases expression ISO sulfluramid results in increased expression of SOD1 mRNA CTD PMID:35337807 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO sulfluramid results in increased expression of SREBF1 mRNA CTD PMID:35337807 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO sulfluramid results in increased expression of SULT2A1 mRNA CTD PMID:35337807 NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      biological role 19805
        xenobiotic 18720
          sulfluramid 22
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    main group molecular entity 19779
                      s-block molecular entity 19617
                        hydrogen molecular entity 19604
                          hydrides 19102
                            inorganic hydride 18114
                              pnictogen hydride 18103
                                nitrogen hydride 18010
                                  azane 17819
                                    ammonia 17818
                                      organic amino compound 17818
                                        primary amino compound 9308
                                          primary amine 6325
                                            primary aliphatic amine 189
                                              ethylamine 66
                                                sulfluramid 22
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