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RGD ID: 70498
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfkb1
Name: nuclear factor kappa B subunit 1
Acc ID: CHEBI:72583
Term: WR-1065
Definition: An alkanethiol that is the N-3-aminopropyl derivative of cysteamine. Used as the S-phosphorylated prodrug, amifostine, for cytoprotection in cancer chemotherapy and radiotherapy.
Chemical ID: MESH:C020174
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkb1multiple interactionsISORGD:7308926480464CTDWR 1065 results in increased activity of [NFKB1 protein binds to RELA protein] WR 1065 results in increased activity of [RELA protein binds to NFKB1 protein]

PMID:11390188 PMID:11917294 PMID:12007958
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