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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:urinary bladder cancer
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Accession:DOID:11054 term browser browse the term
Definition:An urinary system cancer that results_in malignant growth located_in the urinary bladder. (DO)
Synonyms:exact_synonym: bladder cancer;   bladder cancers;   cancer of bladder;   cancer of the bladder;   malignant tumor of urinary bladder;   tumor of the bladder
 narrow_synonym: BLADDER CANCER, TRANSITIONAL CELL, SOMATIC
 primary_id: MESH:D001749
 alt_id: OMIM:109800
 xref: GARD:12210;   ICD10CM:C67;   ICD9CM:188;   MONDO:0001187;   NCI:C2901;   NCI:C9334
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
urinary bladder cancer term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase ISO CTD Direct Evidence: marker/mechanism CTD PMID:29644616 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 disease_progression ISO protein:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:36115647 PMID:18190825 RGD:2291891 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alox12 arachidonate 12-lipoxygenase, 12S type ISO protein:increased expression:urinary bladder RGD PMID:14532840 RGD:2315608 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Amacr alpha-methylacyl-CoA racemase severity ISO RGD PMID:18648853 RGD:2315629 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255 		JBrowse link
G Amfr autocrine motility factor receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:9241080 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Ang angiogenin ISO protein:increased expression:plasma
protein:increased expression:urine		 RGD PMID:15912517 PMID:15329320 RGD:2325700, RGD:2325704 NCBI chr15:24,312,711...24,323,361 JBrowse link
G Ankfy1 ankyrin repeat and FYVE domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr10:57,312,246...57,383,964
Ensembl chr10:57,312,246...57,383,964 		JBrowse link
G Anpep alanyl aminopeptidase, membrane ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility ISO RGD PMID:19041121 RGD:2315660 NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) ISO CTD Direct Evidence: marker/mechanism CTD PMID:22306368 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Areg amphiregulin disease_progression ISO mRNA:increased expression:urinary bladder RGD PMID:11507076 PMID:11133810 RGD:2292661, RGD:2292662 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arid1a AT-rich interaction domain 1A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar		 PMID:21822268 PMID:25741868 PMID:32888375 PMID:34942405 NCBI chr 5:145,908,173...145,981,552
Ensembl chr 5:145,908,181...145,985,564 		JBrowse link
G As3mt arsenite methyltransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22747749 PMID:29669044 PMID:29859237 PMID:32539094 NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872 		JBrowse link
G Asap1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 7:95,786,130...96,093,111
Ensembl chr 7:95,787,818...96,092,754 		JBrowse link
G Asxl2 ASXL transcriptional regulator 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121791 NCBI chr 6:26,425,017...26,514,899
Ensembl chr 6:26,425,954...26,507,477 		JBrowse link
G Atm ATM serine/threonine kinase ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar		 PMID:8755918 PMID:9043869 PMID:9450874 PMID:9463314 PMID:9497252 More... NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp5f1d ATP synthase F1 subunit delta ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 7:9,560,604...9,565,919
Ensembl chr 7:9,560,608...9,565,929 		JBrowse link
G Atp5mc2 ATP synthase membrane subunit c locus 2 ISO DNA:hypermethylation:promoter RGD PMID:26929985 RGD:14696811 NCBI chr 7:133,791,341...133,799,713
Ensembl chr 7:133,791,342...133,799,733 		JBrowse link
G Aurka aurora kinase A disease_progression ISO mRNA, protein:increased expression:urinary bladder RGD PMID:18485461 RGD:2293871 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390 		JBrowse link
G Axin1 axin 1 susceptibility ISO DNA:SNPs:5'utr: (rs12921862, rs1805105, rs370681) (human) RGD PMID:31143301 RGD:150527861 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Bap1 Brca1 associated protein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25231345 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO RGD PMID:18452128 RGD:2296023 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator severity ISO DNA:hypermethylation:promoter
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:36115647 PMID:18094410 PMID:18342927 RGD:2293014, RGD:2292910 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 disease_progression ISO RGD PMID:18342927 RGD:2292910 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12926068 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO protein:increased expression:urinary bladder RGD PMID:17905101 PMID:18089718 RGD:2293096, RGD:2293094 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bptf bromodomain PHD finger transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121791 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Brca1 BRCA1, DNA repair associated ISO DNA:hypermethylation:promoter
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 ClinVar
RGD		 PMID:7894493 PMID:8460636 PMID:8554067 PMID:8968102 PMID:9150154 More... RGD:2293014 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Brca2 BRCA2, DNA repair associated ISO ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar PMID:2673801 PMID:8673091 PMID:8896551 PMID:8988179 PMID:9150172 More... NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567 		JBrowse link
G C8h11orf65 similar to human chromosome 11 open reading frame 65 ISO ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar PMID:8755918 PMID:9450874 PMID:9463314 PMID:9497252 PMID:9733514 More... NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748 		JBrowse link
G Calhm1 calcium homeostasis modulator 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 1:246,030,269...246,032,988
Ensembl chr 1:246,030,269...246,032,988 		JBrowse link
G Car9 carbonic anhydrase 9 disease_progression ISO RGD PMID:14520462 RGD:2293197 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Casp3 caspase 3 disease_progression ISO RGD PMID:17267327 RGD:2298949 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 susceptibility
disease_progression		 ISO DNA:polymorphism, deletion: :1263A>G, 293del (human)
DNA:SNP:exon:p.Q221R (rs1052576) (human)		 RGD PMID:19412632 PMID:19252927 RGD:2315929, RGD:2315930 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 severity ISO protein:increased expression:urinary bladder RGD PMID:12866378 RGD:2289110 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cbx7 chromobox 7 severity ISO mRNA:decreased expression:urinary bladder (human) RGD PMID:18984978 RGD:9587361 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccnd1 cyclin D1 ISO protein:increased expression:bladder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:36115647 PMID:12372886 RGD:13602096 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 disease_progression ISO RGD PMID:16482499 RGD:2316012 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccne1 cyclin E1 severity
disease_progression		 ISO protein:decreased expression:urinary bladder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20972438 PMID:27514407 PMID:16739882 PMID:18047954 RGD:2289267, RGD:2296035 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccng1 cyclin G1 ISO mRNA:decreased expression:bladder (human) RGD PMID:27982046 RGD:151361200 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:16361570 RGD:7248437 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cd44 CD44 molecule ISO RGD PMID:16321281 RGD:2289357 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd82 Cd82 molecule disease_progression ISO protein:decreased expression:urinary bladder RGD PMID:14706010 PMID:17290345 RGD:2289401, RGD:2289391 NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809 		JBrowse link
G Cd9 CD9 molecule disease_progression ISO RGD PMID:14534881 RGD:2326207 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cdc25a cell division cycle 25A ISO RGD PMID:17145867 RGD:2715645 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdc25b cell division cycle 25B disease_progression ISO RGD PMID:19383904 RGD:2739695 NCBI chr 3:118,407,127...118,417,272
Ensembl chr 3:118,407,128...118,417,272 		JBrowse link
G Cdh1 cadherin 1 disease_progression ISO
IEP		 protein:decreased expression:urinary bladder
CTD Direct Evidence: marker/mechanism
Protein:increased expression:cytoplasm		 CTD
RGD		 PMID:17520682 PMID:26901067 PMID:17760743 PMID:17167984 RGD:2289491, RGD:1599549 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh13 cadherin 13 ISO DNA:hypermethylation:promoter RGD PMID:18094410 RGD:2293014 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 ISO RGD PMID:17145867 RGD:2715645 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 disease_progression IEP
ISO		 protein:increased expression:urinary bladder
DNA:amplification		 RGD PMID:16896691 PMID:11971182 RGD:2289144, RGD:2299056 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar		 PMID:18640142 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B susceptibility
disease_progression		 ISO RGD PMID:18027869 PMID:18334837 RGD:2293595, RGD:2293592 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO DNA:hypermethylation:promoter
protein:increased expression:urinary bladder
DNA:deletion
CTD Direct Evidence: marker/mechanism|therapeutic
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar
RGD		 PMID:7777061 PMID:7987387 PMID:8668202 PMID:8755727 PMID:8834170 More... RGD:2296052, RGD:2296048, RGD:2289687 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdkn2a_v1 cyclin-dependent kinase inhibitor 2A, variant 1 ISO DNA:deletion RGD PMID:15897688 RGD:2289687
G Cdkn2b cyclin-dependent kinase inhibitor 2B disease_progression ISO DNA:deletion:urinary bladder RGD PMID:15590562 PMID:16624482 RGD:2289696, RGD:7248757 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Chd6 chromodomain helicase DNA binding protein 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr 3:149,596,509...149,757,765
Ensembl chr 3:149,596,509...149,757,755 		JBrowse link
G Chek2 checkpoint kinase 2 susceptibility
treatment		 ISO
IEP		 DNA:mutations: :multiple RGD PMID:17918154 PMID:21396995 RGD:2289704, RGD:10401655 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Clptm1l CLPTM1-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:19151717 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain ISO mRNA, protein:increased expression:bladder (human) RGD PMID:30066698 RGD:401900123 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Comt catechol-O-methyltransferase ISO protein:increased expression:urinary bladder, urine RGD PMID:15596044 RGD:2289726 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Crebbp CREB binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csf3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:7525883 PMID:17515069 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Ctnna1 catenin alpha 1 disease_progression ISO RGD PMID:17760743 RGD:2289491 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnna3 catenin alpha 3 ISO ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar NCBI chr20:23,614,469...25,200,026
Ensembl chr20:23,623,560...25,199,978 		JBrowse link
G Ctnnb1 catenin beta 1 disease_progression ISO
ISS		 ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder
OMIM:109800		 ClinVar
MouseDO
RGD		 PMID:10192393 PMID:10666372 PMID:25157968 PMID:26619011 PMID:26822237 More... RGD:2289829 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsb cathepsin B ISO protein:increased activity:transitional cell carcinoma (human) RGD PMID:15183956 RGD:2315615 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 ISO DNA:SNP RGD PMID:19252927 RGD:2315930 NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 ISO RGD PMID:17406000 RGD:7257712 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 no_association ISO DNA:polymorphism: :2455A>G (human)
DNA:polymorphisms: :3801T>C (human)		 RGD PMID:21990318 PMID:18979064 PMID:18200441 RGD:7257730, RGD:7257733, RGD:7257736 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 ISO RGD PMID:21990318 RGD:7257730 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 ISO RGD PMID:16985032 RGD:6903918 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp4b1 cytochrome P450, family 4, subfamily b, polypeptide 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18713828 NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348 		JBrowse link
G Dapk1 death associated protein kinase 1 ISO DNA:hypermethylation RGD PMID:12124340 RGD:734875 NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991 		JBrowse link
G Dnmt1 DNA methyltransferase 1 ISO protein:increased expression (in humans) RGD PMID:14634451 RGD:2301220 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dusp1 dual specificity phosphatase 1 disease_progression ISO RGD PMID:17690186 RGD:2298694 NCBI chr10:16,680,478...16,683,275 JBrowse link
G E2f1 E2F transcription factor 1 disease_progression ISO mRNA:increased expression:bladder RGD PMID:20421545 RGD:13602004 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 disease_progression ISO protein:decreased expression:urothelium: RGD PMID:24917520 RGD:10401219 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720 		JBrowse link
G Egfr epidermal growth factor receptor disease_progression ISO protein:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar
RGD		 PMID:11723127 PMID:23523951 PMID:28492532 PMID:18006009 PMID:16685269 RGD:2289943, RGD:2298502 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Eno2 enolase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22613180 PMID:17951193 RGD:2293738 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Eomes eomesodermin ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 8:118,181,340...118,189,186
Ensembl chr 8:118,181,777...118,188,316 		JBrowse link
G Ep300 E1A binding protein p300 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Ephx1 epoxide hydrolase 1 disease_progression ISO DNA:SNPs RGD PMID:19252927 RGD:2315930 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 disease_progression ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar
RGD		 PMID:22908275 PMID:34291863 PMID:16685269 PMID:16771730 RGD:2298502, RGD:2289934 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 disease_progression ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar
RGD		 PMID:26619011 PMID:16685269 RGD:2298502 NCBI chr 7:994,549...1,015,876
Ensembl chr 7:996,225...1,015,525 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 disease_progression ISO protein:decreased expression:urinary bladder RGD PMID:18006009 PMID:16685269 RGD:2289943, RGD:2298502 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit disease_progression ISO ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:9238033 PMID:11335038 PMID:19085937 PMID:19934020 PMID:24121791 More... RGD:11252208 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102 		JBrowse link
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:20062074 NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121792 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Esr1 estrogen receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16712894 PMID:35764155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 severity ISO protein:increased expression:urinary bladder urothelium (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16700038 PMID:23612777 RGD:7364758 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit ISO mRNA:increased expression:urinary bladder RGD PMID:21539681 RGD:126781700 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2 coagulation factor II, thrombin severity ISO protein:increased expression:urine RGD PMID:22236518 RGD:6893573 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fanca FA complementation group A ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24121791 PMID:19237606 RGD:11344902 NCBI chr19:51,304,126...51,362,586
Ensembl chr19:51,304,021...51,362,527 		JBrowse link
G Fas Fas cell surface death receptor susceptibility ISO DNA:polymorphisms:promoter:-1377G>A,-670A>G
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:9070496 PMID:16538171 RGD:2290063 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand susceptibility ISO DNA:polymorphisms:promoter:-844T>C RGD PMID:16538171 RGD:2290063 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fbxw8 F-box and WD repeat domain containing 8 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr12:38,426,466...38,517,076
Ensembl chr12:38,426,444...38,516,424 		JBrowse link
G Fermt2 FERM domain containing kindlin 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21624607 NCBI chr15:18,682,927...18,751,959
Ensembl chr15:18,682,927...18,751,811 		JBrowse link
G Fgf1 fibroblast growth factor 1 ISO RGD PMID:11908679 RGD:2290291 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf2 fibroblast growth factor 2 ISO RGD PMID:11908679 RGD:2290291 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 ISO DNA:hypermethylation, loss of heterozygosity, deletions:exon (human)
associated with Acrocephalosyndactylia (MeSH:D000168)		 RGD PMID:10602477 PMID:16969861 RGD:2301193, RGD:2289664 NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 severity
disease_progression		 ISO DNA:mutations
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism
protein:increased expression:urinary bladder		 ClinVar
CTD
OMIM
RGD		 PMID:1908846 PMID:7647778 PMID:7649548 PMID:7670477 PMID:7702086 More... RGD:2301223, RGD:2301224, RGD:2301225, RGD:2301222, RGD:2289864 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase ISO protein:decreased expression:urinary bladder
associated with Schistosomiasis;DNA:hypermethylation:urinary bladder		 RGD PMID:15591090 PMID:11751381 PMID:15154012 RGD:2301232, RGD:2289897, RGD:2301233 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Fn1 fibronectin 1 ISO protein:increased expression:urine RGD PMID:20012564 RGD:7205680 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Ggh gamma-glutamyl hydrolase ISO CTD Direct Evidence: marker/mechanism CTD PMID:19815704 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20179202 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gpx1 glutathione peroxidase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15247771 PMID:35764155 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:36115647 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 susceptibility ISO DNA:deletion: : (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18505952 PMID:20972438 PMID:18544563 RGD:6906879 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gsto2 glutathione S-transferase omega 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22306368 NCBI chr 1:246,731,314...246,757,592
Ensembl chr 1:246,732,089...246,753,866 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 ISO
IEP		 mRNA:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:7729958 PMID:12500666 PMID:22306368 PMID:18544563 PMID:9111193 More... RGD:6906879, RGD:6906883, RGD:10401939 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 susceptibility ISO DNA:deletion: : (human) RGD PMID:18544563 RGD:6906879 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22306368 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ISO mRNA:increased expression:urinary bladder
DNA:SNP
DNA:hypomethylation		 RGD PMID:18950807 PMID:9886562 PMID:18262338 PMID:11726548 RGD:2306168, RGD:2306184, RGD:2306171, RGD:2306180 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G Hdac4 histone deacetylase 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21507255 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:36115647 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk1 hexokinase 1 treatment IDA RGD PMID:23893687 RGD:11353960 NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hmbs hydroxymethylbilane synthase ISO urinary bladder transitional cell carcinoma; mRNA:decreased expression:tumor:in matched malignant and non-malignant sample pairs (p = 0.008) (human) RGD PMID:16600798 RGD:2301681 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmgb3 high mobility group box 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30639441 NCBI chr  X:149,296,303...149,301,290
Ensembl chr  X:149,296,375...149,301,292 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22109888 NCBI chr  X:74,085,871...74,094,488
Ensembl chr  X:74,085,875...74,094,441 		JBrowse link
G Hoxa9 homeobox A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26332997 NCBI chr 4:81,323,235...81,329,344
Ensembl chr 4:81,323,382...81,326,358 		JBrowse link
G Hras HRas proto-oncogene, GTPase disease_progression ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism		 ClinVar
OMIM
CTD
RGD		 PMID:2228319 PMID:2278634 PMID:2999610 PMID:3537694 PMID:6092966 More... RGD:2314833, RGD:11060144 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A treatment ISO RGD PMID:19914824 RGD:7242743 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Icam1 intercellular adhesion molecule 1 ISO protein:increased expression:serum: RGD PMID:7686390 RGD:11520780 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifnb1 interferon beta 1 ISO CTD Direct Evidence: therapeutic CTD PMID:2297754 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma treatment ISO protein:decreased expression:serum RGD PMID:22906662 PMID:11219496 RGD:6893349, RGD:8157619 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19415693 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:21347663 PMID:12544349 RGD:2290028 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
G Igsf21 immunoglobin superfamily, member 21 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 5:152,287,834...152,512,174
Ensembl chr 5:152,287,835...152,512,174 		JBrowse link
G Il1b interleukin 1 beta disease_progression ISO mRNA:increased expression:urinary bladder tumor (human) RGD PMID:21308147 RGD:7175327 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist susceptibility ISO DNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)
DNA:repeats:intron:IVS2+914_1000dup multiple (human)		 RGD PMID:19489682 PMID:16698387 RGD:6907081, RGD:6907367 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 treatment ISO CTD Direct Evidence: therapeutic CTD
RGD		 PMID:1949363 PMID:3495671 PMID:3262172 RGD:8663471 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29415082 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634 		JBrowse link
G Isl1 ISL LIM homeobox 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26332997 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Jak2 Janus kinase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36115647 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jup junction plakoglobin disease_progression
severity		 ISO DNA, protein:mutations, increased expression:urinary bladder
protein:altered localization:tumor:loss of membrane expression associated with higher grade (p<0.05), higher stage (p<0.05), and poor survival (p<0.05)		 RGD PMID:9783980 PMID:11585741 PMID:17363521 RGD:2291880, RGD:2301748, RGD:2289818 NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057 		JBrowse link
G Kcnj12 potassium inwardly-rectifying channel, subfamily J, member 12 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492 		JBrowse link
G Kdm4a lysine demethylase 4A ISO mRNA:increased expression:urinary bladder (human) RGD PMID:23603248 RGD:9587435 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Kdm4b lysine demethylase 4B ISO mRNA, protein:increased expression:urinary bladder (human) RGD PMID:21930796 RGD:9587740 NCBI chr 9:1,158,737...1,237,233
Ensembl chr 9:1,158,752...1,236,543 		JBrowse link
G Kdm5b lysine demethylase 5B ISO mRNA:increased expression:urinary bladder (human) RGD PMID:20226085 RGD:9587778 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872 		JBrowse link
G Kdm6a lysine demethylase 6A ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 CTD
ClinVar		 PMID:21822268 PMID:23076834 PMID:23913813 PMID:25741868 PMID:27777708 More... NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
G Kdr kinase insert domain receptor severity ISO RGD PMID:12940780 PMID:12215294 RGD:2291949, RGD:2301758 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor ISO RGD PMID:12547718 RGD:2292136 NCBI chr13:44,775,106...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase ISO urinary bladder small cell carcinoma RGD PMID:15502806 RGD:2292430 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf5 KLF transcription factor 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27514407 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445 		JBrowse link
G Kmt2a lysine methyltransferase 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kmt2c lysine methyltransferase 2C ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr 4:9,620,638...9,834,787
Ensembl chr 4:9,609,627...9,833,539 		JBrowse link
G Kmt2d lysine methyltransferase 2D ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121791 NCBI chr 7:129,980,744...130,022,088
Ensembl chr 7:129,962,887...130,020,325 		JBrowse link
G Kras KRAS proto-oncogene, GTPase ISO transitional cell bladder carcinoma, OMIM:109800
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Bladder cancer, transitional cell, somatic | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM
RGD		 PMID:1553789 PMID:6695174 PMID:12110640 PMID:12460918 PMID:14982869 More... RGD:1600467 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt16 keratin 16 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20186695 NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt5 keratin 5 IEP RGD PMID:7507402 RGD:1600196 NCBI chr 7:132,846,132...132,851,861
Ensembl chr 7:132,846,136...132,851,850 		JBrowse link
G Lama2 laminin subunit alpha 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530 		JBrowse link
G Lig1 DNA ligase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8631603 NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413 		JBrowse link
G Loxl1 lysyl oxidase-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17456585 NCBI chr 8:58,691,763...58,716,365
Ensembl chr 8:58,692,593...58,716,356 		JBrowse link
G Loxl4 lysyl oxidase-like 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17456585 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Urinary bladder cancer ClinVar PMID:2999610 PMID:3537694 PMID:6092966 PMID:6330729 PMID:7177195 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Magea9 MAGE family member A9 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17290406 NCBI chr  X:142,619,282...142,624,654
Ensembl chr  X:142,619,395...142,624,653 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 ISO RGD PMID:15665277 RGD:2306057 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 ISO mRNA:splice variant:exon 2: (human) RGD PMID:32601196 RGD:155230826 NCBI chr12:2,591,312...2,600,534
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mdm2 MDM2 proto-oncogene severity ISO mRNA:increased expression:bladder RGD PMID:27798881 RGD:13602098 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase susceptibility ISO DNA:polymorphisms:cds:p.L53L, p.L84F (human) RGD PMID:15885889 RGD:2317672 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mir100 microRNA 100 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30026881 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir132 microRNA 132 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796 		JBrowse link
G Mir145 microRNA 145 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30026881 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir152 microRNA 152 severity ISO miRNA:decreased expression:urinary bladder RGD PMID:30015946 RGD:19165141 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir186 microRNA 186 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34291859 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Mir193b microRNA 193b ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr10:1,317,742...1,317,824
Ensembl chr10:1,317,742...1,317,824 		JBrowse link
G Mir221 microRNA 221 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir27a microRNA 27a ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir34b microRNA 34b ISO CTD Direct Evidence: marker/mechanism CTD PMID:30026881 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327 		JBrowse link
G Mir494 microRNA 494 ameliorates ISO RGD PMID:36098468 RGD:156431053 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir532 microRNA 532 ISO CTD Direct Evidence: marker/mechanism CTD PMID:30639441 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir93 microRNA 93 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir99a microRNA 99a ISO CTD Direct Evidence: marker/mechanism CTD PMID:30026881 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mki67 marker of proliferation Ki-67 IEP protein:increased expression:urinary bladder RGD PMID:20367636 RGD:2317708 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mlh1 mutL homolog 1 disease_progression ISO RGD PMID:15296997 RGD:2293518 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Mmp1 matrix metallopeptidase 1 severity ISO DNA:insertion:promoter:g.-1607insG (human)
protein:increased expression:urine (human)		 RGD PMID:17986285 PMID:11705862 RGD:7207077, RGD:7207140 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 ISO urinary bladder transitional-cell carcinomas RGD PMID:11054671 RGD:2293609 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30548095 PMID:17466450 RGD:2290395 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30548095 PMID:17466450 RGD:2290395 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14729580 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease susceptibility ISO DNA:snp:3' utr:c.2501A>G rs2155209 (human)
ClinVar Annotator: match by term: Malignant tumor of urinary bladder		 ClinVar
RGD		 PMID:28492532 PMID:18638378 RGD:2317733 NCBI chr 8:11,618,876...11,680,451
Ensembl chr 8:11,632,354...11,678,279 		JBrowse link
G Msh2 mutS homolog 2 disease_progression ISO DNA:mutation
DNA:mutations: :multiple
associated with Lynch syndrome
protein:decreased expression:urinary bladder		 RGD PMID:18389386 PMID:26385421 PMID:22883484 PMID:18254781 RGD:2293502, RGD:126790580, RGD:126790557, RGD:2293503 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Msh6 mutS homolog 6 disease_progression ISO protein:decreased expression:urinary bladder RGD PMID:18254781 RGD:2293503 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956 		JBrowse link
G Mt-atp8 mitochondrially encoded ATP synthase membrane subunit 8 ISO DNA:deletion: :(human) RGD PMID:15254717 RGD:2302294 NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961 		JBrowse link
G Mt-cyb mitochondrially encoded cytochrome b ISO DNA:deletion:cds RGD PMID:18245469 RGD:2298953 NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278 		JBrowse link
G Mt-nd2 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 ISO DNA:deletion: :(human) RGD PMID:15254717 RGD:2302294 NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942 		JBrowse link
G Mt1 metallothionein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16565513 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A ISO CTD Direct Evidence: marker/mechanism CTD PMID:7729958 PMID:16565513 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16854967 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase susceptibility
no_association		 ISO DNA:transition:cds:g.677C>T (human)
CTD Direct Evidence: marker/mechanism
protein:missense mutation:cds:p.A222V (human)
DNA:transversion:cds:g.1298A>C (human)
DNA:transition, transversion, haplotype:cds:g.677C>T, g.1298A>C (human)		 CTD
RGD		 PMID:22747749 PMID:22126575 PMID:17311259 PMID:19837268 PMID:20146887 RGD:6893457, RGD:6893597, RGD:6893521, RGD:6893516 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:36115647 PMID:19261747 RGD:10040979 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase susceptibility ISO DNA:polymorphism: :2756A>G(human) RGD PMID:19837268 RGD:6893521 NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822 		JBrowse link
G Muc1 mucin 1, cell surface associated ISO protein:increased expression:serum: RGD PMID:10468735 RGD:7245967 NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Muc5b mucin 5B, oligomeric mucus/gel-forming ISO DNA:repeats RGD PMID:19191526 RGD:7349339 NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor susceptibility
disease_progression		 ISO DNA:snp, haplotype:enhancer:g.-30772G>T rs9642880 (human)
CTD Direct Evidence: marker/mechanism
protein:decreased expression:urinary bladder urothelium (human)		 CTD
RGD		 PMID:2228319 PMID:23284801 PMID:20939013 PMID:22028816 RGD:7207401, RGD:7207427, RGD:7207418 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nat1 N-acetyltransferase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16003747 NCBI chr16:22,218,217...22,238,516
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Nat2 N-acetyltransferase 2 susceptibility ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10022756 PMID:15717312 PMID:18505952 PMID:20972438 PMID:24221535 More... RGD:8552670 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520 		JBrowse link
G Ncan neurocan ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21822268 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Ncstn nicastrin ISS OMIM:109800 MouseDO NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29321541 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase ISO RGD PMID:17726579 RGD:2302550 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nf1 neurofibromin 1 ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar PMID:8069310 PMID:10090487 PMID:10712197 PMID:10862084 PMID:10980545 More... NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 ISO mRNA:increased expression:urinary bladder RGD PMID:7614395 RGD:2299071 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 ISO mRNA:increased expression:urinary bladder RGD PMID:7614395 RGD:2299071 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538 		JBrowse link
G Nos3 nitric oxide synthase 3 ISO protein:increased expression:urinary bladder RGD PMID:10475345 RGD:2292089 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IDA
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:8631603 PMID:21213404 RGD:10401939 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrsn1 neurensin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr17:39,806,238...39,824,550
Ensembl chr17:39,806,238...39,823,813 		JBrowse link
G Or8s5 olfactory receptor family 8 subfamily S member 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 7:129,490,113...129,491,030
Ensembl chr 7:129,486,292...129,496,949 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:25783786 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744 		JBrowse link
G Phb1 prohibitin 1 IEP mRNA:increased expression:urinary bladder RGD PMID:8062216 RGD:2292407 NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO ClinVar Annotator: match by term: Malignant tumor of urinary bladder ClinVar NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha ISO CTD Direct Evidence: marker/mechanism CTD PMID:34755307 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Plau plasminogen activator, urokinase treatment IDA
ISO		 protein:increased expression:urinary bladder (human)
DNA:snp:3' utr:g.4065C>T (human)		 RGD PMID:19010488 PMID:18336603 PMID:16825821 RGD:4144867, RGD:7241213, RGD:7241144 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plk1 polo-like kinase 1 severity ISO RGD PMID:16837776 PMID:15761500 RGD:2299938, RGD:2299940 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Pmf1 polyamine-modulated factor 1 disease_progression ISO RGD PMID:19088041 RGD:30296651 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component susceptibility ISO DNA:SNP: :rs6463524 (human) RGD PMID:19692168 RGD:2315025 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
G Polb DNA polymerase beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:8631603 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Pon1 paraoxonase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Por cytochrome p450 oxidoreductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:8631603 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma IEP protein:decreased expression:urinary bladder RGD PMID:18712722 RGD:2301870 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp3cc protein phosphatase 3 catalytic subunit gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:29275364 NCBI chr15:45,289,917...45,362,012
Ensembl chr15:45,290,373...45,361,832 		JBrowse link
G Prdm2 PR/SET domain 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825 		JBrowse link
G Prkca protein kinase C, alpha severity
disease_progression		 ISO protein:increased expression:urinary bladder
protein:altered localization:urinary bladder		 RGD PMID:16008942 PMID:15922420 RGD:2292455, RGD:2298669 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Prss3 serine protease 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15987713 NCBI chr 4:70,203,088...70,206,562
Ensembl chr 4:70,203,088...70,206,562 		JBrowse link
G Psca prostate stem cell antigen ISO CTD Direct Evidence: marker/mechanism CTD PMID:19648920 PMID:20083643 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746 		JBrowse link
G Psmb2 proteasome 20S subunit beta 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 5:138,970,564...139,002,715
Ensembl chr 5:138,970,533...139,021,137 		JBrowse link
G Pten phosphatase and tensin homolog disease_progression ISO
ISS		 DNA:mutations: :multiple
ClinVar Annotator: match by term: Malignant tumor of urinary bladder
OMIM:109800
protein:decreased expression:urinary bladder		 ClinVar
MouseDO
RGD		 PMID:9140396 PMID:9256433 PMID:9735393 PMID:9811831 PMID:10051603 More... RGD:2292515, RGD:2291891 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 disease_progression
susceptibility		 ISO CTD Direct Evidence: marker/mechanism
DNA:SNP:3' utr:837T>C (human)		 CTD
RGD		 PMID:10582676 PMID:10873095 PMID:12442003 PMID:12664575 PMID:16098373 More... RGD:2300200, RGD:5508302, RGD:2300127 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rab27a RAB27A, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:34291859 NCBI chr 8:73,782,730...73,836,630
Ensembl chr 8:73,782,694...73,847,829 		JBrowse link
G Rab27b RAB27B, member RAS oncogene family ISO CTD Direct Evidence: marker/mechanism CTD PMID:34291859 NCBI chr18:63,597,554...63,794,124
Ensembl chr18:63,600,937...63,757,180 		JBrowse link
G Ralbp1 ralA binding protein 1 ISO mRNA, protein:increased expression:urinary bladder RGD PMID:17606711 RGD:2324917 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
G Ralgps1 Ral GEF with PH domain and SH3 binding motif 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 3:16,433,323...16,670,276
Ensembl chr 3:16,433,742...16,669,972 		JBrowse link
G Rassf1 Ras association domain family member 1 ISO DNA:hypermethylation
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15987713 PMID:18702824 PMID:12222680 RGD:2299860, RGD:2291977 NCBI chr 8:108,225,023...108,236,164
Ensembl chr 8:108,225,023...108,236,164 		JBrowse link
G Rb1 RB transcriptional corepressor 1 disease_progression ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM
RGD		 PMID:1352883 PMID:2181449 PMID:2601691 PMID:7704558 PMID:7881418 More... RGD:2299888 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit disease_progression ISO RGD PMID:18188593 PMID:18089718 RGD:2298753, RGD:2293094 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Retn resistin ISO protein:increased expression:urine RGD PMID:18373357 RGD:7207154 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Rhoa ras homolog family member A disease_progression ISO protein:increased expression:urinary bladder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19896475 PMID:12855641 RGD:2298872 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 IEP mRNA:increased expression:bladder (rat) RGD PMID:21139803 RGD:5133688 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Runx3 RUNX family transcription factor 3 ISO DNA:hypermethylation:promoter RGD PMID:16230397 RGD:2302553 NCBI chr 5:147,360,587...147,419,161
Ensembl chr 5:147,360,994...147,419,156 		JBrowse link
G S100a8 S100 calcium binding protein A8 IEP mRNA:increased expression:urinary bladder RGD PMID:17970044 RGD:2316906 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 IEP mRNA:increased expression:urinary bladder RGD PMID:17970044 RGD:2316906 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G S100b S100 calcium binding protein B IEP mRNA:increased expression:urinary bladder urothelium RGD PMID:17970044 RGD:2316906 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Serpine1 serpin family E member 1 ISO RGD PMID:19010488 RGD:4144867 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sfn stratifin disease_progression ISO protein:increased expression:urothelium (human) RGD PMID:17645415 RGD:2299928 NCBI chr 5:145,826,722...145,827,994
Ensembl chr 5:145,826,201...145,831,314 		JBrowse link
G Slc11a1 solute carrier family 11 member 1 disease_progression ISO DNA:repeat, polymorphism:promoter, cds:p.D543N (human) RGD PMID:16516037 RGD:5684951 NCBI chr 9:75,957,193...75,968,115
Ensembl chr 9:75,957,316...75,968,101 		JBrowse link
G Slc12a7 solute carrier family 12 member 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 1:29,472,692...29,554,246
Ensembl chr 1:29,472,692...29,554,302 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21760912 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Smad2 SMAD family member 2 ISO RGD PMID:15548366 RGD:2299964 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad4 SMAD family member 4 ISO protein:decreased expression:urinary bladder RGD PMID:11783019 RGD:2299972 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121791 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056 		JBrowse link
G Smc1b structural maintenance of chromosomes 1B ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121791 NCBI chr 7:116,180,987...116,242,778
Ensembl chr 7:116,180,987...116,242,744 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 disease_progression ISO DNA:hypermethylation:promoter RGD PMID:16242928 PMID:17522834 RGD:2298906, RGD:2298903 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Sod1 superoxide dismutase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35764155 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:14729580 PMID:18930813 PMID:17974967 RGD:7175539 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sox2 SRY-box transcription factor 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29396848 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox4 SRY-box transcription factor 4 ISO RGD PMID:16585165 RGD:1581304 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sparc secreted protein acidic and cysteine rich disease_progression ISO RGD PMID:11696817 PMID:17149610 RGD:2300024, RGD:2300021 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 disease_progression ISO mRNA, protein:decreased expression:urinary bladder RGD PMID:16327984 RGD:2300384 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO RGD PMID:21483670 RGD:6903265 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:11723127 PMID:17093206 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srsf9 serine and arginine rich splicing factor 9 ISO mRNA:increased expression:urinary bladder epithelium (human) RGD PMID:22178073 RGD:11040443 NCBI chr12:41,278,225...41,284,502
Ensembl chr12:41,275,687...41,284,499 		JBrowse link
G Stag2 STAG2 cohesin complex component ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121789 PMID:24121791 PMID:24121792 NCBI chr  X:120,974,687...121,105,677
Ensembl chr  X:120,974,857...121,105,677 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:36115647 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 ISO RGD PMID:14643027 RGD:1581442 NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562 		JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24121792 NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219 		JBrowse link
G Terc telomerase RNA component disease_progression ISO RNA:increased expression:urinary bladder
RNA:increased expression:urine		 RGD PMID:16104909 PMID:17644139 RGD:2291967, RGD:2291986 NCBI chr 2:112,815,654...112,816,041 JBrowse link
G Tert telomerase reverse transcriptase ISO protein:increased expression:urine
ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:19151717 PMID:20871597 PMID:22037553 PMID:23066086 PMID:23348503 More... RGD:2291986 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tff1 trefoil factor 1 ISO protein:increased expression:urinary bladder RGD PMID:18283638 RGD:2291996 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Tfrc transferrin receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:16904380 NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 ISO RGD PMID:9363992 RGD:2302036 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Thbs1 thrombospondin 1 severity ISO protein:decreased expression:bladder RGD PMID:20299037 RGD:13602099 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 disease_progression ISO protein:decreased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:30548095 PMID:17374529 PMID:17466450 RGD:2298521, RGD:2290395 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 ISO DNA:hypermethylation:promoter RGD PMID:18082200 RGD:2290411 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tlr2 toll-like receptor 2 ISO DNA:deletion:promoter:−196_−174del (human) RGD PMID:23142523 RGD:7207893 NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630 		JBrowse link
G Tlr4 toll-like receptor 4 treatment ISO RGD PMID:19788935 RGD:7240556 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 ISO DNA:hypermethylation:promoter RGD PMID:16234815 RGD:2290489 NCBI chr 9:50,445,947...50,733,473
Ensembl chr 9:50,436,079...50,733,475 		JBrowse link
G Tnf tumor necrosis factor ISO CTD Direct Evidence: therapeutic CTD PMID:1674182 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b ISO DNA:missense mutation:cds:p.E228A (c.683A>C) (human) RGD PMID:16217763 RGD:11038717 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Top2a DNA topoisomerase II alpha disease_progression ISO RGD PMID:19913893 RGD:2315121 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 disease_progression ISO protein:increased expression:urinary bladder
ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:224644 PMID:1565143 PMID:1591732 PMID:1631151 PMID:1683921 More... RGD:2290536 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 disease_progression ISO RGD PMID:19690775 RGD:2315430 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 disease_progression ISO mRNA:increased expression:urinary bladder RGD PMID:10383132 RGD:2291836 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19502594 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Tsc1 TSC complex subunit 1 ISO ClinVar Annotator: match by term: Bladder cancer | ClinVar Annotator: match by term: Malignant tumor of urinary bladder | ClinVar Annotator: match by term: Urinary bladder cancer ClinVar PMID:9242607 PMID:9328481 PMID:9803264 PMID:9863590 PMID:9924605 More... NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Tymp thymidine phosphorylase disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11103787 PMID:15841086 PMID:16937303 RGD:2293716 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Tyms thymidylate synthetase IDA RGD PMID:18463958 RGD:2317413 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536 		JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I ISO radiation-induced dysplasia and carcinoma in situ; protein:increased expression:bladder urothelium:increased in Chernobyl victims vs controls from uncontaminated areas of the Ukraine (p<0.001) (human) RGD PMID:16407042 RGD:2301343 NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443
Ensembl chr10:69,701,618...69,702,443 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15615884 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO mRNA:increased expression:bladder RGD PMID:22895562 RGD:13605607 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfc vascular endothelial growth factor C disease_progression ISO RGD PMID:17094484 RGD:2315482 NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848 		JBrowse link
G Vegfd vascular endothelial growth factor D disease_progression ISO RGD PMID:17970053 RGD:2315479 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor IEP mRNA:decreased expression:urinary bladder RGD PMID:19399409 RGD:2325183 NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377 		JBrowse link
G Vwa3a von Willebrand factor A domain containing 3A ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr 1:175,293,782...175,355,588
Ensembl chr 1:175,293,873...175,355,602 		JBrowse link
G Wif1 Wnt inhibitory factor 1 disease_progression ISO protein:decreased expression:urinary bladder
DNA:hypermethylation:promoter		 RGD PMID:14517837 PMID:18325051 RGD:727214, RGD:2291868 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360 		JBrowse link
G Wnt7b Wnt family member 7B ISO superficial, NOT invasive RGD PMID:9461004 RGD:2299932 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Xdh xanthine dehydrogenase ISO protein:decreased activity:urinary bladder RGD PMID:20087949 RGD:7247647 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 susceptibility
no_association		 ISO DNA:polymorphism: :p.R399Q
DNA:SNP: p.R399Q (human)
DNA:polymorphisms: :multiple		 RGD PMID:18765423 PMID:18272472 PMID:17425776 RGD:2302568, RGD:150530493, RGD:2302572 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Yjefn3 YjeF N-terminal domain containing 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:26039340 NCBI chr16:19,533,742...19,539,759
Ensembl chr16:19,533,788...19,539,728 		JBrowse link
G Zfp609 zinc finger protein 609 ISO CTD Direct Evidence: marker/mechanism CTD PMID:35567596 NCBI chr 8:66,214,553...66,349,319
Ensembl chr 8:66,214,555...66,317,977 		JBrowse link
bladder carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr3 fibroblast growth factor receptor 3 ISO ClinVar Annotator: match by term: Urinary bladder carcinoma ClinVar PMID:7773297 PMID:8589699 PMID:8845844 PMID:9438390 PMID:9790257 More... NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Hras HRas proto-oncogene, GTPase ISO ClinVar Annotator: match by term: Urinary bladder carcinoma ClinVar PMID:16170316 PMID:16372351 PMID:16443854 PMID:16835863 PMID:17601930 More... NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Lrrc56 leucine rich repeat containing 56 ISO ClinVar Annotator: match by term: Urinary bladder carcinoma ClinVar PMID:16170316 PMID:16372351 PMID:16443854 PMID:16835863 PMID:17601930 More... NCBI chr 1:196,299,843...196,315,170
Ensembl chr 1:196,299,846...196,315,172 		JBrowse link
G Pmf1 polyamine-modulated factor 1 disease_progression ISO RGD PMID:22682992 RGD:30296649 NCBI chr 2:173,848,074...173,868,272
Ensembl chr 2:173,848,074...173,868,270 		JBrowse link
bladder squamous cell carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pten phosphatase and tensin homolog disease_progression ISO associated with schistosomiasis;protein:decreased expression:urothelium (human) RGD PMID:26916953 RGD:127285612 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
bladder urothelial carcinoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actl7a actin-like 7a ISO RGD PMID:29058301 RGD:13831338 NCBI chr 5:71,447,447...71,450,440
Ensembl chr 5:71,447,071...71,450,908 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 disease_progression ISO mRNA:increased expression:urinary bladder (human) RGD PMID:31964418 RGD:153344516 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 disease_progression ISO mRNA:increased expression:urinary bladder (human) RGD PMID:31964418 RGD:153344516 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 severity ISO protein:increased expression:urothelial cells (human) RGD PMID:28507621 RGD:38500205 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Kdm6a lysine demethylase 6A susceptibility ISO associated with upper tract urothelial carcinoma; DNA:mutations:multiple: (human) RGD PMID:30352907 RGD:150429735 NCBI chr  X:4,337,466...4,477,100
Ensembl chr  X:4,337,750...4,477,062 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      cancer 5509
        organ system cancer 5263
          urinary system cancer 680
            urinary bladder cancer 307
              Urachal Adenocarcinoma 0
              bladder carcinoma + 9
              bladder dome cancer 0
              bladder lateral wall cancer 0
              bladder lymphoma 0
              bladder neck cancer 0
              bladder sarcoma 0
              bladder sarcomatoid transitional cell carcinoma 0
              bladder trigone cancer 0
              urachus cancer + 0
              ureteric orifice cancer 0
              urinary bladder anterior wall cancer 0
              urinary bladder posterior wall cancer 0
Path 2
Term Annotations click to browse term
  disease 18969
    disease of cellular proliferation 7691
      Neoplasms by Site 7144
        Urogenital Neoplasms 2193
          Urologic Neoplasms 734
            urinary system cancer 680
              urinary bladder cancer 307
                Urachal Adenocarcinoma 0
                bladder carcinoma + 9
                bladder dome cancer 0
                bladder lateral wall cancer 0
                bladder lymphoma 0
                bladder neck cancer 0
                bladder sarcoma 0
                bladder sarcomatoid transitional cell carcinoma 0
                bladder trigone cancer 0
                urachus cancer + 0
                ureteric orifice cancer 0
                urinary bladder anterior wall cancer 0
                urinary bladder posterior wall cancer 0
paths to the root