Mir193b (microRNA 193b) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Mir193b (microRNA 193b) Rattus norvegicus
Analyze
Symbol: Mir193b
Name: microRNA 193b
RGD ID: 9685090
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated post-transcriptional gene silencing. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; hematopoietic stem cell differentiation; and sensory perception of sound. Predicted to be located in extracellular exosome. Orthologous to human MIR193B (microRNA 193b); INTERACTS WITH acrylamide; atrazine; bisphenol A.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: rno-mir-193b
RGD Orthologs
Human
Mouse
Dog
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,824,944 - 1,825,026 (+)NCBIGRCr8
mRatBN7.2101,317,742 - 1,317,824 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,317,742 - 1,317,824 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,014,459 - 6,014,541 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,551,297 - 34,551,379 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,331,694 - 1,331,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01430,331,049 - 30,331,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1430,331,049 - 30,331,131 (-)EnsemblRnor6.0rn6Rnor6.0
Celera10380,964 - 381,046 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A Preliminary Study of the Value of Plasma microRNA-193b and Soluble Urokinase-Type Plasminogen Activator Receptor in Identifying Patients with Early-Stage Colorectal Cancer and. Liu KL, etal., Clin Lab. 2017 Nov 1;63(11):1949-1953. doi: 10.7754/Clin.Lab.2017.170726.
2. Association of miR-193b down-regulation and miR-196a up-regulation with clinicopathological features and prognosis in gastric cancer. Mu YP, etal., Asian Pac J Cancer Prev. 2014;15(20):8893-900. doi: 10.7314/apjcp.2014.15.20.8893.
3. LncRNA H19 regulates smooth muscle cell functions and participates in the development of aortic dissection through sponging miR-193b-3p. Ren M, etal., Biosci Rep. 2021 Jan 29;41(1):BSR20202298. doi: 10.1042/BSR20202298.
4. MicroRNA-193b inhibits the proliferation, migration and invasion of gastric cancer cells via targeting cyclin D1. Wang L, etal., Acta Histochem. 2016 May;118(4):323-30. doi: 10.1016/j.acthis.2016.02.001. Epub 2016 Apr 9.
Additional References at PubMed
PMID:16381832   PMID:20439489   PMID:20660734   PMID:23329697   PMID:23646144   PMID:25751060   PMID:35249453   PMID:37059928  


Genomics

Comparative Map Data
Mir193b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8101,824,944 - 1,825,026 (+)NCBIGRCr8
mRatBN7.2101,317,742 - 1,317,824 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl101,317,742 - 1,317,824 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx106,014,459 - 6,014,541 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01034,551,297 - 34,551,379 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0101,331,694 - 1,331,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01430,331,049 - 30,331,131 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1430,331,049 - 30,331,131 (-)EnsemblRnor6.0rn6Rnor6.0
Celera10380,964 - 381,046 (+)NCBICelera
Cytogenetic Map10q11NCBI
MIR193B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381614,303,967 - 14,304,049 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1614,303,967 - 14,304,049 (+)EnsemblGRCh38hg38GRCh38
GRCh371614,397,824 - 14,397,906 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361614,305,324 - 14,305,406 (+)NCBINCBI36Build 36hg18NCBI36
Celera1614,573,940 - 14,574,022 (+)NCBICelera
Cytogenetic Map16p13.12NCBI
HuRef1614,314,879 - 14,314,961 (+)NCBIHuRef
CHM1_11614,397,749 - 14,397,831 (+)NCBICHM1_1
T2T-CHM13v2.01614,341,202 - 14,341,284 (+)NCBIT2T-CHM13v2.0
Mir193b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391613,267,387 - 13,267,465 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1613,267,387 - 13,267,465 (+)EnsemblGRCm39 Ensembl
GRCm381613,449,523 - 13,449,601 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1613,449,523 - 13,449,601 (+)EnsemblGRCm38mm10GRCm38
MGSCv371613,449,616 - 13,449,694 (+)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1614,051,595 - 14,051,673 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map169.29NCBI
MIR193B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1628,878,050 - 28,878,108 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl628,878,050 - 28,878,108 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha630,240,668 - 30,240,726 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0629,041,272 - 29,041,330 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl629,041,272 - 29,041,330 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1628,843,281 - 28,843,339 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0628,731,758 - 28,731,816 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0629,151,720 - 29,151,778 (-)NCBIUU_Cfam_GSD_1.0


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 5 7 3 3 3 7 8 25 4 9 4 7
Below cutoff 4 3 2 1 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_128671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000073318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl101,317,742 - 1,317,824 (+)Ensembl
Rnor_6.0 Ensembl1430,331,049 - 30,331,131 (-)Ensembl
RefSeq Acc Id: NR_128671
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8101,824,944 - 1,825,026 (+)NCBI
mRatBN7.2101,317,742 - 1,317,824 (+)NCBI
Rnor_6.01430,331,049 - 30,331,131 (-)NCBI
Celera10380,964 - 381,046 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:9685090 AgrOrtholog
BioCyc Gene G2FUF-26229 BioCyc
Ensembl Genes ENSRNOG00000046587 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000073318 ENTREZGENE
miRBase MI0030355 ENTREZGENE
NCBI Gene Mir193b ENTREZGENE
PhenoGen Mir193b PhenoGen
RatGTEx ENSRNOG00000046587 RatGTEx
RNAcentral URS00007E34D5 RNACentral
  URS00007E4ECB RNACentral
  URS00007E4F1F RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-04-09 Mir193b  microRNA 193b  Mir193b  microRNA mir-193b  Name updated 61478 APPROVED
2014-12-16 Mir193b  microRNA mir-193b      Symbol and Name status set to provisional 70820 PROVISIONAL