Magea9 (MAGE family member A9) - Rat Genome Database

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Gene: Magea9 (MAGE family member A9) Rattus norvegicus
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Symbol: Magea9
Name: MAGE family member A9
RGD ID: 1565494
Description: Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MAGEA10 (MAGE family member A10); INTERACTS WITH benzo[a]pyrene; 17beta-estradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC317297; MGC114427; similar to melanoma antigen family A, 5; uncharacterized protein LOC317297
RGD Orthologs
Human
Mouse
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X147,655,721 - 147,661,093 (+)NCBIGRCr8
mRatBN7.2X142,619,282 - 142,624,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX142,619,395 - 142,624,653 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX144,817,604 - 144,820,374 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X148,342,571 - 148,345,341 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X145,892,301 - 145,895,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X147,491,247 - 147,496,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX147,493,880 - 147,496,649 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X147,512,048 - 147,514,818 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X149,962,817 - 149,965,587 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX138,499,498 - 138,502,268 (+)NCBICelera
Cytogenetic MapXq36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data
Magea9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X147,655,721 - 147,661,093 (+)NCBIGRCr8
mRatBN7.2X142,619,282 - 142,624,654 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX142,619,395 - 142,624,653 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX144,817,604 - 144,820,374 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X148,342,571 - 148,345,341 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X145,892,301 - 145,895,071 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X147,491,247 - 147,496,650 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX147,493,880 - 147,496,649 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X147,512,048 - 147,514,818 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X149,962,817 - 149,965,587 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX138,499,498 - 138,502,268 (+)NCBICelera
Cytogenetic MapXq36NCBI
MAGEA9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X149,781,877 - 149,787,737 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX149,781,930 - 149,787,737 (+)EnsemblGRCh38hg38GRCh38
GRCh38.p14 EnsemblX149,581,653 - 149,587,459 (-)EnsemblGRCh38hg38GRCh38
GRCh37X148,863,593 - 148,869,399 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X148,671,402 - 148,677,206 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X148,569,255 - 148,575,058NCBI
CeleraX149,194,726 - 149,200,530 (+)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX137,617,079 - 137,622,883 (-)NCBIHuRef
CHM1_1X148,824,495 - 148,830,295 (+)NCBICHM1_1
T2T-CHM13v2.0X148,047,665 - 148,053,471 (+)NCBIT2T-CHM13v2.0
Magea9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X63,217,154 - 63,222,385 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX63,217,154 - 63,222,384 (+)EnsemblGRCm39 Ensembl
GRCm38X64,173,548 - 64,178,779 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX64,173,548 - 64,178,778 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X61,426,723 - 61,431,953 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X60,434,227 - 60,439,443 (+)NCBIMGSCv36mm8
CeleraX50,571,393 - 50,576,623 (+)NCBICelera
Cytogenetic MapXA7.1NCBI
cM MapX34.57NCBI
MAGEA9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X124,358,947 - 124,372,897 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606562,001,202 - 62,006,328 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Magea9
19 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:178
Count of miRNA genes:142
Interacting mature miRNAs:155
Transcripts:ENSRNOT00000037881
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X126975089152453651Rat

Markers in Region
AI179244  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X142,624,485 - 142,624,600 (+)MAPPERmRatBN7.2
Rnor_6.0X147,496,482 - 147,496,596NCBIRnor6.0
Rnor_5.0X147,514,650 - 147,514,764UniSTSRnor5.0
RGSC_v3.4X149,965,419 - 149,965,533UniSTSRGSC3.4
CeleraX138,502,100 - 138,502,214UniSTS
Cytogenetic MapXq37UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 14
Low 1 1 4 5 13 4
Below cutoff 5 7 2 5 2 4 6 9 4 7 1 4

Sequence


RefSeq Acc Id: ENSRNOT00000037881   ⟹   ENSRNOP00000053408
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX142,620,262 - 142,624,653 (+)Ensembl
Rnor_6.0 EnsemblX147,493,880 - 147,496,649 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102737   ⟹   ENSRNOP00000082572
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX142,619,395 - 142,624,653 (+)Ensembl
RefSeq Acc Id: NM_001419558   ⟹   NP_001406487
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X147,655,721 - 147,661,093 (+)NCBI
mRatBN7.2X142,619,282 - 142,624,654 (+)NCBI
RefSeq Acc Id: NM_001419559   ⟹   NP_001406488
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X147,656,677 - 147,661,093 (+)NCBI
mRatBN7.2X142,620,238 - 142,624,654 (+)NCBI
RefSeq Acc Id: ENSRNOP00000053408   ⟸   ENSRNOT00000037881
RefSeq Acc Id: ENSRNOP00000082572   ⟸   ENSRNOT00000102737
RefSeq Acc Id: NP_001406487   ⟸   NM_001419558
- UniProtKB: Q4V8H6 (UniProtKB/TrEMBL),   A6K515 (UniProtKB/TrEMBL),   A0A8I5ZXB3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001406488   ⟸   NM_001419559
- UniProtKB: Q4V8H6 (UniProtKB/TrEMBL),   A6K515 (UniProtKB/TrEMBL),   A0A8I5ZXB3 (UniProtKB/TrEMBL)
Protein Domains
MAGE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8H6-F1-model_v2 AlphaFold Q4V8H6 1-300 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565494 AgrOrtholog
BioCyc Gene G2FUF-841 BioCyc
Ensembl Genes ENSRNOG00000023016 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037881 ENTREZGENE
  ENSRNOT00000037881.5 UniProtKB/TrEMBL
  ENSRNOT00000102737 ENTREZGENE
  ENSRNOT00000102737.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.1200 UniProtKB/TrEMBL
  1.10.10.1210 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7446557 IMAGE-MGC_LOAD
InterPro MAGE UniProtKB/TrEMBL
  MAGE UniProtKB/TrEMBL
  MAGE_WH1 UniProtKB/TrEMBL
  MAGE_WH2 UniProtKB/TrEMBL
KEGG Report rno:317297 UniProtKB/TrEMBL
MGC_CLONE MGC:114427 IMAGE-MGC_LOAD
NCBI Gene 317297 ENTREZGENE
PANTHER MAGE FAMILY MEMBER A9 UniProtKB/TrEMBL
  PTHR11736 UniProtKB/TrEMBL
Pfam MAGE UniProtKB/TrEMBL
PhenoGen Magea9 PhenoGen
PROSITE MAGE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000023016 RatGTEx
SMART MAGE UniProtKB/TrEMBL
UniProt A0A8I5ZXB3 ENTREZGENE, UniProtKB/TrEMBL
  A6K515 ENTREZGENE
  Q4V8H6 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6K515 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-09 Magea9  MAGE family member A9  MGC114427  similar to melanoma antigen family A, 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 MGC114427  similar to melanoma antigen family A, 5      Symbol and Name status set to provisional 70820 PROVISIONAL