Gene: Tgfbr1 (transforming growth factor, beta receptor 1) Rattus norvegicus
Symbol: Tgfbr1
Name: transforming growth factor, beta receptor 1
Description: ENCODES a protein that exhibits ATP binding; protein complex binding; protein heterodimerization activity; INVOLVED IN aging; animal organ regeneration; digestive tract development; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Hypertension, Pulmonary; Kidney Diseases; Leiomyoma; FOUND IN apical plasma membrane; basolateral plasma membrane; caveola; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activin receptor-like kinase 5; Alk5; MGC93659; serine/threonine-protein kinase receptor R4; Skr4; tbetaR-I; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; Tgfr-1; transforming growth factor beta receptor I; transforming growth factor, beta receptor I; transforming growth factor-beta receptor type I
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0563,056,071 - 63,119,635 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0567,575,578 - 67,643,666 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.0569,079,391 - 69,097,816 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4563,976,868 - 64,034,058 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1563,981,949 - 64,034,967 (+)NCBI
Celera565,882,184 - 65,907,477 (-)NCBI
Cytogenetic Map5q22NCBImapview

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tgfbr1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3852
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-10-11
Status: ACTIVE