Gene: Tgfbr1 (transforming growth factor, beta receptor 1) Rattus norvegicus
Symbol: Tgfbr1
Name: transforming growth factor, beta receptor 1
Description: ENCODES a protein that exhibits ATP binding; protein complex binding; protein heterodimerization activity; INVOLVED IN aging; digestive tract development; embryo implantation; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Hypertension, Pulmonary; Kidney Diseases; Leiomyoma; FOUND IN apical plasma membrane; basolateral plasma membrane; caveola; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activin receptor-like kinase 5; Alk5; MGC93659; serine/threonine-protein kinase receptor R4; Skr4; tbetaR-I; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; Tgfr-1; transforming growth factor beta receptor I; transforming growth factor, beta receptor I; transforming growth factor-beta receptor type I
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0563,056,079 - 63,124,107+NCBI
Rat Cytogenetic Map5q22 NCBI
RGSC Genome Assembly v5.0567,575,578 - 67,643,666+NCBI
RGSC Genome Assembly v5.0569,079,391 - 69,097,816+NCBI
RGSC Genome Assembly v3.4563,976,868 - 64,034,058+NCBI
Rat Celera Assembly565,882,184 - 65,907,477-NCBI
Genome Assembly 3.1563,981,949 - 64,034,967+NCBI
Launch Genome Browser (GBrowse)     Launch JBrowse

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Tgfbr1
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 3852
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-12-29
Status: ACTIVE