Gene: Tgfbr1 (transforming growth factor, beta receptor 1) Rattus norvegicus
Symbol: Tgfbr1
Name: transforming growth factor, beta receptor 1
Description: ENCODES a protein that exhibits ATP binding; protein complex binding; protein heterodimerization activity; INVOLVED IN aging; digestive tract development; embryo implantation; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Hypertension, Pulmonary; Kidney Diseases; Leiomyoma; FOUND IN apical plasma membrane; basolateral plasma membrane; caveola; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activin receptor-like kinase 5; Alk5; MGC93659; serine/threonine-protein kinase receptor R4; Skr4; tbetaR-I; TGF-beta receptor type I; TGF-beta receptor type-1; TGF-beta type I receptor; Tgfr-1; transforming growth factor beta receptor I; transforming growth factor, beta receptor I; transforming growth factor-beta receptor type I
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0563,056,071 - 63,119,635 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0569,079,391 - 69,097,816 (+)NCBIRnor5.0rn5Rnor5.0
Rnor_5.0567,575,578 - 67,643,666 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4563,976,868 - 64,034,058 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1563,981,949 - 64,034,967 (+)NCBI
Celera565,882,184 - 65,907,477 (-)NCBI
Cytogenetic Map5q22NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tgfbr1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 3852
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-09
Status: ACTIVE