Gene: Kit (v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog) Rattus norvegicus
Symbol: Kit
Name: v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
Description: ENCODES a protein that exhibits protein tyrosine kinase activity; cytokine binding (ortholog); protease binding (ortholog); INVOLVED IN epithelial cell proliferation; germ cell migration; peptidyl-tyrosine phosphorylation; PARTICIPATES IN acute myeloid leukemia pathway; cytokine mediated signaling pathway; endocytosis pathway; ASSOCIATED WITH Infertility, Male; Mammary Neoplasms, Experimental; Adenoma, Oxyphilic (ortholog); FOUND IN acrosomal vesicle; cytoplasm; cytoplasmic side of plasma membrane; INTERACTS WITH 2,5-hexanedione; 2-acetamidofluorene; 6-propyl-2-thiouracil
Type: protein-coding
Also known as: c-kit receptor tyrosine kinase; mast/stem cell growth factor receptor; mast/stem cell growth factor receptor Kit; protein kinase
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01435,072,131 - 35,149,642-NCBI
Rat Cytogenetic Map14p11 NCBI
RGSC Genome Assembly v5.01434,901,860 - 34,979,384-NCBI
RGSC Genome Assembly v3.41434,906,043 - 34,984,819-NCBI
Rat Celera Assembly1431,837,543 - 31,913,518-NCBI
Genome Assembly 3.11434,906,042 - 34,984,819-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Kit
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 620568
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2015-05-12
Status: ACTIVE