beta-naphthoflavone - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	beta-naphthoflavone	go back to main search page
Accession:	CHEBI:77013	browse the term
Definition:	An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.
Synonyms:	exact_synonym:	3-phenyl-1H-benzo[f]chromen-1-one
	related_synonym:	3-phenyl-1H-naphtho(2,1-b)pyran-1-one; 5,6-benzoflavone; Formula=C19H12O2; InChI=1S/C19H12O2/c20-16-12-18(14-7-2-1-3-8-14)21-17-11-10-13-6-4-5-9-15(13)19(16)17/h1-12H; InChIKey=OUGIDAPQYNCXRA-UHFFFAOYSA-N; SMILES=O=c1cc(oc2ccc3ccccc3c12)-c1ccccc1; benzo[f]flavone; beta-NF
	xref:	CAS:6051-87-2; DrugBank:DB06732
	xref_mesh:	MESH:D019324
	xref:	PMID:11697852; PMID:16730384; PMID:18535361; PMID:19969063; PMID:20060304; PMID:20843940; PMID:21624442; PMID:22167217; PMID:24163404; PMID:3924427; PMID:8430058; Reaxys:18991; Wikipedia:Beta-Naphthoflavone

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Genes (1127)

beta-naphthoflavone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

RIKEN cDNA 1700019D03 gene

decreases expression

beta-Naphthoflavone results in decreased expression of C2ORF88 mRNA

NCBI chr 1:52,961,483...53,031,816
Ensembl chr 1:52,961,483...53,059,338

G

alpha-1-B glycoprotein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of A1BG mRNA

NCBI chr15:60,789,438...60,793,119
Ensembl chr15:60,768,708...60,794,861

G

alpha-2-macroglobulin

decreases expression

beta-Naphthoflavone results in decreased expression of A2M mRNA

NCBI chr 6:121,612,920...121,656,197
Ensembl chr 6:121,612,335...121,656,186

G

alpha 1,3-galactosyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of A3GALT2 mRNA

NCBI chr 4:128,653,051...128,663,091
Ensembl chr 4:128,649,157...128,663,091

G

arylacetamide deacetylase

decreases expression

beta-Naphthoflavone results in decreased expression of AADAC mRNA

NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581

G

ATP-binding cassette, sub-family B member 6

increases expression

beta-Naphthoflavone results in increased expression of ABCB6 mRNA

NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036

G

ATP-binding cassette, sub-family C member 1

increases expression

beta-Naphthoflavone results in increased expression of ABCC1 mRNA

NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601

G

ATP-binding cassette, sub-family member 2

increases expression
decreases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC2 mRNA
beta-Naphthoflavone results in decreased expression of ABCC2 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA

PMID:11752103 PMID:15833929 PMID:16426233 PMID:19737606 PMID:20607812 More...

NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179

G

ATP-binding cassette, sub-family C member 3

multiple interactions
increases expression

[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC3 mRNA
beta-Naphthoflavone results in increased expression of ABCC3 mRNA

PMID:15833929 PMID:19118567 PMID:23994337

NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823

G

ATP-binding cassette, sub-family C member 4

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of ABCC4 mRNA

NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631

G

ATP-binding cassette, sub-family C member 5

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC5 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC5 mRNA

NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144

G

ATP-binding cassette, sub-family C member 6

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ABCC6 mRNA
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC6 mRNA

NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726

G

ATP-binding cassette, sub-family C member 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ABCC9 mRNA

NCBI chr 6:142,533,592...142,648,472
Ensembl chr 6:142,533,588...142,648,041

G

ATP-binding cassette, sub-family E member 1

increases expression

beta-Naphthoflavone results in increased expression of ABCE1 mRNA

NCBI chr 8:80,410,071...80,438,369
Ensembl chr 8:80,410,091...80,438,369

G

ATP binding cassette subfamily G member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ABCG1 mRNA

NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962

G

ATP binding cassette subfamily G member 2 (Junior blood group)

increases expression

beta-Naphthoflavone results in increased expression of ABCG2 mRNA

NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661

G

acetyl-Coenzyme A carboxylase beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACACB mRNA

NCBI chr 5:114,284,748...114,388,822
Ensembl chr 5:114,284,596...114,388,822

G

ArfGAP with coiled-coil, ankyrin repeat and PH domains 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACAP2 mRNA

NCBI chr16:30,911,230...31,020,105
Ensembl chr16:30,911,230...31,020,063

G

acetyl-Coenzyme A acetyltransferase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACAT2 mRNA
beta-Naphthoflavone results in decreased expression of ACAT2 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ACAT2 mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr17:13,161,929...13,179,612
Ensembl chr17:13,161,777...13,179,634

G

acyl-Coenzyme A binding domain containing 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACBD3 mRNA

NCBI chr 1:180,553,608...180,581,769
Ensembl chr 1:180,553,608...180,581,769

G

angiotensin I converting enzyme

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACE mRNA

NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790

G

acyl-CoA thioesterase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ACOT1 mRNA

NCBI chr12:84,056,276...84,064,444
Ensembl chr12:84,056,264...84,065,145

G

acyl-CoA thioesterase 7

increases expression

beta-Naphthoflavone results in increased expression of ACOT7 mRNA

NCBI chr 4:152,258,872...152,356,312
Ensembl chr 4:152,262,591...152,356,312

G

acyl-CoA synthetase long-chain family member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACSL3 mRNA

NCBI chr 1:78,635,600...78,685,462
Ensembl chr 1:78,635,542...78,685,460

G

activin A receptor, type II-like 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ACVRL1 mRNA
beta-Naphthoflavone results in decreased expression of ACVRL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr15:101,026,403...101,043,217
Ensembl chr15:101,026,403...101,043,217

G

aminoacylase 1

increases expression

beta-Naphthoflavone results in increased expression of ACY1 mRNA

NCBI chr 9:106,310,180...106,315,594
Ensembl chr 9:106,310,180...106,315,518

G

ADAM metallopeptidase domain 12

decreases expression

beta-Naphthoflavone results in decreased expression of ADAM12 mRNA

NCBI chr 7:133,484,928...133,826,859
Ensembl chr 7:133,484,928...133,833,875

G

ADAM metallopeptidase domain 19

decreases expression

beta-Naphthoflavone results in decreased expression of ADAM19 mRNA

NCBI chr11:45,945,329...46,038,174
Ensembl chr11:45,946,819...46,038,170

G

a disintegrin and metallopeptidase domain 2

increases expression

beta-Naphthoflavone results in increased expression of ADAM2 mRNA

NCBI chr14:66,264,778...66,315,300
Ensembl chr14:66,264,778...66,315,182

G

ADAM-like, decysin 1

increases expression

beta-Naphthoflavone results in increased expression of ADAMDEC1 mRNA

NCBI chr14:68,800,829...68,819,535
Ensembl chr14:68,800,829...68,819,544

G

adenylate cyclase 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADCY3 mRNA
beta-Naphthoflavone results in decreased expression of ADCY3 mRNA

PMID:18164116 PMID:32858204

NCBI chr12:4,183,397...4,263,525
Ensembl chr12:4,183,103...4,263,525

G

adenylate cyclase 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADCY8 mRNA

NCBI chr15:64,570,884...64,794,145
Ensembl chr15:64,568,933...64,794,145

G

adhesion G protein-coupled receptor E5

decreases expression

beta-Naphthoflavone results in decreased expression of ADGRE5 mRNA

NCBI chr 8:84,449,874...84,467,812
Ensembl chr 8:84,449,880...84,467,955

G

adhesion G protein-coupled receptor G1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG1 mRNA
beta-Naphthoflavone results in decreased expression of ADGRG1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:95,701,321...95,740,836
Ensembl chr 8:95,701,379...95,740,845

G

adhesion G protein-coupled receptor G2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ADGRG2 mRNA

NCBI chr X:159,173,315...159,281,072
Ensembl chr X:159,173,686...159,281,066

G

adhesion G protein-coupled receptor G6

decreases expression

beta-Naphthoflavone results in decreased expression of ADGRG6 mRNA

NCBI chr10:14,278,327...14,421,467
Ensembl chr10:14,278,327...14,421,403

G

adhesion G protein-coupled receptor L2

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ADGRL2 mRNA]

NCBI chr 3:148,521,491...149,150,832
Ensembl chr 3:148,521,219...148,696,191

G

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of ADH7 mRNA

NCBI chr 3:137,903,828...137,937,803
Ensembl chr 3:137,923,521...137,939,143

G

alcohol dehydrogenase, iron containing, 1

decreases expression

beta-Naphthoflavone results in decreased expression of ADHFE1 mRNA

NCBI chr 1:9,618,173...9,648,195
Ensembl chr 1:9,618,173...9,650,898

G

adrenomedullin

increases expression

beta-Naphthoflavone results in increased expression of ADM mRNA

NCBI chr 7:110,226,864...110,229,027
Ensembl chr 7:110,226,868...110,229,027

G

adrenergic receptor, beta 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ADRB3 mRNA

NCBI chr 8:27,715,804...27,720,833
Ensembl chr 8:27,715,804...27,740,644

G

adhesion regulating molecule 1 26S proteasome ubiquitin receptor

increases expression

beta-Naphthoflavone results in increased expression of ADRM1 mRNA

NCBI chr 2:179,813,381...179,818,076
Ensembl chr 2:179,813,278...179,818,079

G

alanine-glyoxylate aminotransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AGXT mRNA

NCBI chr 1:93,062,962...93,073,143
Ensembl chr 1:93,062,962...93,073,143

G

aryl-hydrocarbon receptor

affects binding
affects localization
decreases expression
increases expression
affects folding
multiple interactions
increases activity
affects response to substance

[beta-Naphthoflavone binds to AHR protein] which binds to ESR1 protein; [beta-Naphthoflavone binds to AHR protein] which binds to ESRRA protein; [beta-Naphthoflavone binds to AHR protein] which binds to NR2F1 protein; beta-Naphthoflavone binds to AHR protein
beta-Naphthoflavone affects the localization of AHR protein
beta-Naphthoflavone results in decreased expression of AHR mRNA; beta-Naphthoflavone results in decreased expression of AHR protein
beta-Naphthoflavone results in increased expression of AHR mRNA
beta-Naphthoflavone affects the folding of AHR protein
AHR protein promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of AHR mRNA]; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]
beta-Naphthoflavone results in increased activity of AHR protein
AHR protein affects the susceptibility to beta-Naphthoflavone
[beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC2 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC3 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC5 mRNA; [beta-Naphthoflavone binds to AHR protein] which results in increased expression of ABCC6 mRNA; [beta-Naphthoflavone binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [beta-Naphthoflavone binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of CSN2 mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of LALBA mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of WAP mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR promotes the reaction [beta-Naphthoflavone results in decreased abundance of Lactic Acid]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ACAT2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of ADGRL2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES2E mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES3 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of COQ10B mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYB5B mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP51 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DHCR7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DMGDH mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of GBP6 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HAGH mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IDI1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IRGM mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MSMO1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MVD mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NAT8F2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NSDHL mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PCSK9 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PMVK mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RCAN2 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RDH11 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of UGCG mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; AHR protein promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; beta-Naphthoflavone binds to and affects the localization of AHR protein; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin binds to AHR protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to BMAL1 protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to PER1 promoter]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]
AHR gene alternative form affects the susceptibility to beta-Naphthoflavone; AHR protein affects the susceptibility to beta-Naphthoflavone
[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]; [beta-Naphthoflavone results in increased activity of AHR protein] which results in decreased chemical synthesis of and results in decreased secretion of Cholesterol; AHR gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]; AHR mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone binds to and results in increased activity of AHR protein; beta-Naphthoflavone binds to and results in increased activity of AHR protein polymorphism; beta-Naphthoflavone binds to and results in increased activity of and results in increased localization of AHR protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein]; beta-Naphthoflavone promotes the reaction [[AHR protein binds to UGT1A1 enhancer] which results in increased expression of UGT1A1 mRNA]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to GSTA1 promoter]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; Carbaryl inhibits the reaction [beta-Naphthoflavone binds to and results in increased activity of AHR protein]; cryptotanshinone promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; dihydrotanshinone I promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]; tanshinone promotes the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]

PMID:3005314 PMID:9407059 PMID:10620335 PMID:11752103 PMID:11752201 More...

NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037

G

aryl-hydrocarbon receptor repressor

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AHRR mRNA
beta-Naphthoflavone results in increased expression of AHRR mRNA

PMID:12520768 PMID:18164116 PMID:25218365

NCBI chr13:74,359,237...74,440,450
Ensembl chr13:74,359,237...74,440,450

G

adenylate kinase 4

decreases expression

beta-Naphthoflavone results in decreased expression of AK4 mRNA

NCBI chr 4:101,273,675...101,324,968
Ensembl chr 4:101,276,474...101,324,192

G

aldo-keto reductase family 1, member A1

increases expression

beta-Naphthoflavone results in increased expression of AKR1A1 mRNA

NCBI chr 4:116,493,707...116,508,871
Ensembl chr 4:116,493,707...116,508,877

G

aldo-keto reductase family 1, member C14

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of AKR1C14 mRNA

NCBI chr13:4,099,015...4,140,569
Ensembl chr13:4,099,011...4,140,688

G

aldo-keto reductase family 1, member C18

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of AKR1C3 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA

PMID:18164116 PMID:19737606 PMID:32151702

NCBI chr13:4,182,614...4,200,645
Ensembl chr13:4,182,614...4,200,653

G

aldo-keto reductase family 1, member C19

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of AKR1C19 mRNA

NCBI chr13:4,283,499...4,298,360
Ensembl chr13:4,278,699...4,302,842

G

aldo-keto reductase family 1, member C20

increases expression

beta-Naphthoflavone results in increased expression of AKR1C1 mRNA

PMID:17253728 PMID:32151702

NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344

G

aldo-keto reductase family 1, member D1

decreases expression

beta-Naphthoflavone results in decreased expression of AKR1D1 mRNA

NCBI chr 6:37,506,913...37,551,856
Ensembl chr 6:37,507,108...37,545,750

G

aldo-keto reductase family 1, member E1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR1E1 mRNA

NCBI chr13:4,641,122...4,659,163
Ensembl chr13:4,640,749...4,659,173

G

aldo-keto reductase family 7, member A5

increases expression

beta-Naphthoflavone results in increased expression of AKR7A2 mRNA; beta-Naphthoflavone results in increased expression of AKR7A2 protein

NCBI chr 4:139,038,005...139,046,097
Ensembl chr 4:139,038,055...139,045,737

G

aminolevulinic acid synthase 2, erythroid

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALAS2 mRNA

NCBI chr X:149,330,443...149,353,614
Ensembl chr X:149,330,371...149,353,634

G

albumin

decreases expression

beta-Naphthoflavone results in decreased expression of ALB mRNA

NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461

G

aldehyde dehydrogenase family 1, subfamily A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH1A1 mRNA

NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829

G

aldehyde dehydrogenase family 1, subfamily A7

increases expression

beta-Naphthoflavone results in increased expression of ALDH1A7 mRNA

NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926

G

aldehyde dehydrogenase 1 family, member B1

increases expression

beta-Naphthoflavone results in increased expression of ALDH1B1 mRNA

NCBI chr 4:45,799,022...45,804,608
Ensembl chr 4:45,799,022...45,804,604

G

aldehyde dehydrogenase family 3, subfamily A1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of ALDH3A1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3A1 mRNA

PMID:1416978 PMID:17998271 PMID:18164116 PMID:23994337 PMID:25218365 More...

NCBI chr11:61,099,336...61,109,244
Ensembl chr11:61,098,363...61,109,247

G

aldehyde dehydrogenase 3 family, member B1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALDH3B1 mRNA

NCBI chr19:3,963,491...3,980,898
Ensembl chr19:3,963,491...3,979,808

G

aldehyde dehydrogenase 3 family, member B3

decreases expression

beta-Naphthoflavone results in decreased expression of ALDH3B2 mRNA

NCBI chr19:4,008,733...4,022,419
Ensembl chr19:4,008,645...4,022,103

G

aldehyde dehydrogenase 8 family, member A1

decreases expression

beta-Naphthoflavone results in decreased expression of ALDH8A1 mRNA

NCBI chr10:21,253,199...21,272,477
Ensembl chr10:21,253,190...21,272,484

G

arachidonate 5-lipoxygenase

increases expression

beta-Naphthoflavone results in increased expression of ALOX5 mRNA

NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139

G

alkaline phosphatase, liver/bone/kidney

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALPL mRNA

NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695

G

adenosine monophosphate deaminase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AMPD3 mRNA

NCBI chr 7:110,367,291...110,411,612
Ensembl chr 7:110,367,413...110,411,612

G

ankyrin repeat domain 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of ANKRD1 mRNA

NCBI chr19:36,089,365...36,097,244
Ensembl chr19:36,089,361...36,097,499

G

acidic nuclear phosphoprotein 32 family member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANP32A mRNA

NCBI chr 9:62,248,637...62,286,084
Ensembl chr 9:62,248,575...62,286,094

G

annexin A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA1 mRNA

NCBI chr19:20,350,798...20,368,035
Ensembl chr19:20,350,792...20,368,308

G

annexin A4

decreases expression

beta-Naphthoflavone results in decreased expression of ANXA4 mRNA

NCBI chr 6:86,713,822...86,770,616
Ensembl chr 6:86,713,822...86,770,566

G

annexin A5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA5 mRNA

NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043

G

annexin A8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ANXA8 mRNA

NCBI chr14:33,807,936...33,822,528
Ensembl chr14:33,807,938...33,822,528

G

amine oxidase, copper-containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of AOC1 mRNA

NCBI chr 6:48,872,189...48,886,122
Ensembl chr 6:48,849,830...48,886,122

G

aldehyde oxidase 3

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of AOX3 mRNA

NCBI chr 1:58,152,294...58,241,380
Ensembl chr 1:58,152,289...58,239,857

G

adaptor protein complex AP-1, sigma 1

increases expression

beta-Naphthoflavone results in increased expression of AP1S1 mRNA

NCBI chr 5:137,063,852...137,074,917
Ensembl chr 5:137,063,847...137,074,989

G

amyloid P component, serum

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APCS mRNA

NCBI chr 1:172,721,528...172,722,516
Ensembl chr 1:172,721,528...172,722,608

G

apelin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of APLN mRNA

NCBI chr X:47,114,023...47,123,730
Ensembl chr X:47,114,023...47,123,730

G

apolipoprotein A-IV

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOA4 mRNA

NCBI chr 9:46,152,142...46,154,756
Ensembl chr 9:46,151,994...46,154,757

G

apolipoprotein A-V

decreases expression

beta-Naphthoflavone results in decreased expression of APOA5 mRNA

NCBI chr 9:46,179,906...46,183,219
Ensembl chr 9:46,179,931...46,183,217

G

apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2

decreases expression

beta-Naphthoflavone results in decreased expression of APOBEC2 mRNA

NCBI chr17:48,726,259...48,739,756
Ensembl chr17:48,726,259...48,739,958

G

apolipoprotein M

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of APOM mRNA

NCBI chr17:35,347,973...35,350,777
Ensembl chr17:35,347,973...35,351,026

G

adenine phosphoribosyl transferase

increases expression

beta-Naphthoflavone results in increased expression of APRT mRNA

NCBI chr 8:123,301,376...123,303,646
Ensembl chr 8:123,301,374...123,303,648

G

aprataxin

increases expression

beta-Naphthoflavone results in increased expression of APTX mRNA

NCBI chr 4:40,682,078...40,703,206
Ensembl chr 4:40,682,382...40,703,194

G

Rho/Rac guanine nucleotide exchange factor 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARHGEF2 mRNA

NCBI chr 3:88,500,427...88,556,839
Ensembl chr 3:88,513,273...88,555,359

G

AT-rich interaction domain 5B

decreases expression

beta-Naphthoflavone results in decreased expression of ARID5B mRNA

NCBI chr10:67,928,353...68,114,596
Ensembl chr10:67,928,350...68,114,570

G

ADP-ribosylation factor-like 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ARL3 mRNA

NCBI chr19:46,519,548...46,561,621
Ensembl chr19:46,519,535...46,561,637

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

ARNT affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; ARNT promotes the reaction [beta-Naphthoflavone results in decreased abundance of Lactic Acid]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]; kaempferol inhibits the reaction [beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]
AHR gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]]; beta-Naphthoflavone promotes the reaction [AHR protein binds to ARNT protein]; beta-Naphthoflavone results in increased activity of [AHR protein binds to ARNT protein]

PMID:17012224 PMID:19901195 PMID:21127131 PMID:21849270 PMID:24486526

NCBI chr 3:95,341,674...95,404,551
Ensembl chr 3:95,341,699...95,404,551

G

aryl hydrocarbon receptor nuclear translocator 2

increases expression

beta-Naphthoflavone results in increased expression of ARNT2 mRNA

NCBI chr 7:83,895,486...84,059,201
Ensembl chr 7:83,895,486...84,059,384

G

arrestin domain containing 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ARRDC2 mRNA

NCBI chr 8:71,287,773...71,293,173
Ensembl chr 8:71,287,773...71,292,364

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain1

increases expression

beta-Naphthoflavone results in increased expression of ASAP1 mRNA

NCBI chr15:63,958,704...64,254,922
Ensembl chr15:63,958,706...64,254,768

G

asparagine synthetase

increases expression

beta-Naphthoflavone results in increased expression of ASNS mRNA

PMID:17175557 PMID:32858204

NCBI chr 6:7,675,169...7,693,209
Ensembl chr 6:7,675,169...7,693,254

G

atos homolog B

increases expression

beta-Naphthoflavone results in increased expression of ATOSB mRNA

NCBI chr 4:43,032,414...43,046,220
Ensembl chr 4:43,032,414...43,046,220

G

ATPase, Na+/K+ transporting, beta 3 polypeptide

increases expression

beta-Naphthoflavone results in increased expression of ATP1B3 mRNA

NCBI chr 9:96,214,708...96,246,368
Ensembl chr 9:96,214,708...96,246,495

G

ATPase, Ca++ transporting, plasma membrane 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP2B2 mRNA

NCBI chr 6:113,720,803...114,019,574
Ensembl chr 6:113,720,792...114,019,574

G

ATP synthase F1 subunit beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein; [Piperonyl Butoxide co-treated with beta-Naphthoflavone] results in decreased expression of ATP5F1B protein

NCBI chr10:127,919,176...127,926,257
Ensembl chr10:127,919,142...127,926,260

G

ATPase, H+ transporting, lysosomal V1 subunit B1

decreases expression

beta-Naphthoflavone results in decreased expression of ATP6V1B1 mRNA

NCBI chr 6:83,719,999...83,735,837
Ensembl chr 6:83,719,972...83,735,837

G

ATPase, H+ transporting, lysosomal V1 subunit C2

decreases expression

beta-Naphthoflavone results in decreased expression of ATP6V1C2 mRNA

NCBI chr12:17,334,722...17,375,700
Ensembl chr12:17,334,722...17,379,360

G

ATPase, Cu++ transporting, beta polypeptide

decreases expression

beta-Naphthoflavone results in decreased expression of ATP7B mRNA

NCBI chr 8:22,482,799...22,550,347
Ensembl chr 8:22,482,801...22,550,321

G

ataxin 10

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ATXN10 mRNA

NCBI chr15:85,220,456...85,348,038
Ensembl chr15:85,220,446...85,347,413

G

ancient ubiquitous protein 1

increases expression

beta-Naphthoflavone results in increased expression of AUP1 mRNA

NCBI chr 6:83,031,483...83,034,663
Ensembl chr 6:83,031,502...83,034,789

G

advillin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AVIL mRNA

NCBI chr10:126,835,933...126,856,857
Ensembl chr10:126,836,578...126,856,863

G

acyl-CoA wax alcohol acyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of AWAT1 mRNA

NCBI chr X:99,615,853...99,621,812
Ensembl chr X:99,615,857...99,621,811

G

UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of B3GALNT1 mRNA

NCBI chr 3:69,481,252...69,506,305
Ensembl chr 3:69,481,491...69,506,293

G

BAF nuclear assembly factor 1

decreases expression

beta-Naphthoflavone results in decreased expression of BANF1 mRNA

NCBI chr19:5,414,661...5,416,904
Ensembl chr19:5,414,666...5,417,196

G

brain abundant, membrane attached signal protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BASP1 mRNA

NCBI chr15:25,363,363...25,413,850
Ensembl chr15:25,363,363...25,413,850

G

branched chain aminotransferase 1, cytosolic

decreases expression

beta-Naphthoflavone results in decreased expression of BCAT1 mRNA

NCBI chr 6:144,939,561...145,021,883
Ensembl chr 6:144,939,561...145,021,910

G

B cell leukemia/lymphoma 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of BCL2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BCL2 mRNA

PMID:21295105 PMID:22687991

NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004

G

B cell CLL/lymphoma 9-like

increases expression

beta-Naphthoflavone results in increased expression of BCL9L mRNA

NCBI chr 9:44,394,103...44,423,203
Ensembl chr 9:44,394,122...44,423,193

G

brain expressed X-linked 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX3 mRNA
beta-Naphthoflavone results in decreased expression of BEX3 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:135,171,002...135,172,727
Ensembl chr X:135,171,002...135,172,727

G

brain expressed X-linked 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BEX4 mRNA

NCBI chr X:135,039,745...135,041,192
Ensembl chr X:135,039,745...135,041,192

G

biglycan

decreases expression

beta-Naphthoflavone results in decreased expression of BGN mRNA

NCBI chr X:72,527,207...72,539,542
Ensembl chr X:72,527,208...72,539,539

G

basic helix-loop-helix family, member e41

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BHLHE41 mRNA

NCBI chr 6:145,803,969...145,811,146
Ensembl chr 6:145,803,969...145,811,284

G

betaine-homocysteine methyltransferase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of BHMT mRNA

NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469

G

baculoviral IAP repeat-containing 3

increases expression

beta-Naphthoflavone results in increased expression of BIRC3 mRNA

NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187

G

baculoviral IAP repeat-containing 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BIRC5 mRNA

NCBI chr11:117,740,063...117,746,569
Ensembl chr11:117,740,077...117,746,569

G

B cell linker

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BLNK mRNA

NCBI chr19:40,917,371...40,982,664
Ensembl chr19:40,917,371...40,982,978

G

biliverdin reductase B

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of BLVRB mRNA

NCBI chr 7:27,147,403...27,165,406
Ensembl chr 7:27,147,403...27,165,569

G

basic helix-loop-helix ARNT like 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of BMAL1 mRNA
beta-Naphthoflavone results in increased expression of BMAL1 mRNA
beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to BMAL1 protein]; beta-Naphthoflavone promotes the reaction [AHR protein binds to BMAL1 protein]; BMAL1 affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]

PMID:18164116 PMID:20106950 PMID:21849270 PMID:32151702

NCBI chr 7:112,777,820...112,913,333
Ensembl chr 7:112,806,672...112,913,333

G

BCL2-related ovarian killer

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BOK mRNA

NCBI chr 1:93,613,297...93,623,492
Ensembl chr 1:93,613,382...93,623,486

G

2,3-bisphosphoglycerate mutase

decreases expression

beta-Naphthoflavone results in decreased expression of BPGM mRNA

NCBI chr 6:34,453,291...34,482,071
Ensembl chr 6:34,453,142...34,482,548

G

bone morphogenic protein/retinoic acid inducible neural specific 1

increases expression

beta-Naphthoflavone results in increased expression of BRINP1 mRNA

NCBI chr 4:68,679,609...68,872,634
Ensembl chr 4:68,679,751...68,872,634

G

B-box and SPRY domain containing

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BSPRY mRNA

NCBI chr 4:62,398,248...62,415,537
Ensembl chr 4:62,398,290...62,415,535

G

BTG anti-proliferation factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of BTG3 mRNA

NCBI chr16:78,156,748...78,174,069
Ensembl chr16:78,129,525...78,174,080

G

C1q and tumor necrosis factor related protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of C1QTNF1 mRNA

NCBI chr11:118,319,187...118,342,608
Ensembl chr11:118,319,029...118,340,789

G

C1q and tumor necrosis factor related protein 6

decreases expression

beta-Naphthoflavone results in decreased expression of C1QTNF6 mRNA

NCBI chr15:78,407,546...78,416,370
Ensembl chr15:78,407,546...78,415,616

G

calcium binding protein 39-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CAB39L mRNA

NCBI chr14:59,678,400...59,786,353
Ensembl chr14:59,678,421...59,823,213

G

calcium channel, voltage-dependent, alpha2/delta subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CACNA2D1 mRNA

NCBI chr 5:16,139,390...16,579,509
Ensembl chr 5:16,139,786...16,579,502

G

calcium channel, voltage-dependent, gamma subunit 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CACNG5 mRNA

NCBI chr11:107,765,431...107,805,881
Ensembl chr11:107,765,431...107,805,881

G

calpain 6

decreases expression

beta-Naphthoflavone results in decreased expression of CAPN6 mRNA

NCBI chr X:142,585,232...142,610,408
Ensembl chr X:142,585,227...142,610,410

G

carbonic anhydrase 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAR11 mRNA

NCBI chr 7:45,348,537...45,354,106
Ensembl chr 7:45,349,267...45,354,106

G

carbonic anhydrase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CA2 mRNA
beta-Naphthoflavone results in decreased expression of CA2 mRNA

PMID:18164116 PMID:32858204

NCBI chr 3:14,951,329...14,965,830
Ensembl chr 3:14,951,333...14,965,830

G

carbonic anhydrase 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CA3 mRNA
beta-Naphthoflavone results in decreased expression of CAR3 mRNA

PMID:18164116 PMID:23994337

NCBI chr 3:14,928,598...14,937,441
Ensembl chr 3:14,928,572...14,937,583

G

caspase 1

decreases expression

beta-Naphthoflavone results in decreased expression of CASP1 mRNA

NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290

G

caspase 3

multiple interactions

beta-Naphthoflavone inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]

NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724

G

caveolin 1, caveolae protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CAV mRNA

NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451

G

Casitas B-lineage lymphoma c

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CBLC mRNA

NCBI chr 7:19,513,643...19,530,734
Ensembl chr 7:19,512,806...19,530,734

G

carbonyl reductase 1

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CBR1 mRNA
beta-Naphthoflavone results in increased expression of CBR1 mRNA

PMID:17569794 PMID:19737545 PMID:19737606

NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393

G

carbonyl reductase 3

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CBR3 mRNA

NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878

G

coiled-coil domain containing 80

decreases expression

beta-Naphthoflavone results in decreased expression of CCDC80 mRNA

NCBI chr16:44,913,770...44,948,287
Ensembl chr16:44,913,765...44,948,440

G

coiled-coil domain containing 85B

increases expression

beta-Naphthoflavone results in increased expression of CCDC85B mRNA

NCBI chr19:5,503,191...5,507,591
Ensembl chr19:5,503,208...5,507,922

G

cholecystokinin

decreases expression

beta-Naphthoflavone results in decreased expression of CCK mRNA

NCBI chr 9:121,318,890...121,324,728
Ensembl chr 9:121,318,890...121,324,760

G

cholecystokinin B receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCKBR mRNA

NCBI chr 7:105,075,201...105,085,546
Ensembl chr 7:105,074,938...105,120,105

G

C-C motif chemokine ligand 2

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCL2 mRNA
beta-Naphthoflavone results in increased expression of CCL2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCL2 mRNA]

PMID:19737545 PMID:21295105 PMID:22687991

NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279

G

C-C motif chemokine ligand 20

decreases expression

beta-Naphthoflavone results in decreased expression of CCL20 mRNA

NCBI chr 1:83,094,487...83,096,888
Ensembl chr 1:83,094,487...83,096,888

G

C-C motif chemokine ligand 22

decreases expression

beta-Naphthoflavone results in decreased expression of CCL22 mRNA

NCBI chr 8:95,472,312...95,478,016
Ensembl chr 8:95,472,218...95,478,327

G

C-C motif chemokine ligand 3

decreases expression

beta-Naphthoflavone results in decreased expression of CCL3 mRNA

NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181

G

C-C motif chemokine ligand 5

decreases expression

beta-Naphthoflavone results in decreased expression of CCL5 mRNA

NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344

G

C-C motif chemokine ligand 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CCL6 mRNA

NCBI chr11:83,478,712...83,483,913
Ensembl chr11:83,478,708...83,483,913

G

cellular communication network factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN1 mRNA

NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736

G

cellular communication network factor 2

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA
beta-Naphthoflavone results in decreased expression of CCN2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA

PMID:18164116 PMID:19737545 PMID:19737606 PMID:32151702

NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581

G

cellular communication network factor 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN5 mRNA

NCBI chr 2:163,662,724...163,675,066
Ensembl chr 2:163,662,781...163,675,066

G

cyclin A1

decreases expression

beta-Naphthoflavone results in decreased expression of CCNA1 mRNA

NCBI chr 3:54,952,890...54,965,055
Ensembl chr 3:54,952,890...54,962,922

G

cyclin A2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNA2 mRNA

NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299

G

cyclin B1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCNB1 mRNA

NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078

G

cyclin B2

decreases expression

beta-Naphthoflavone results in decreased expression of CCNB2 mRNA

NCBI chr 9:70,314,971...70,328,836
Ensembl chr 9:70,314,974...70,328,829

G

cyclin D1

decreases expression

beta-Naphthoflavone results in decreased expression of CCND1 mRNA

NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662

G

chaperonin containing TCP1 subunit 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCT3 mRNA

NCBI chr 3:88,204,442...88,229,073
Ensembl chr 3:88,204,423...88,229,074

G

CD24a antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD24 mRNA

NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261

G

CD276 antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD276 mRNA

NCBI chr 9:58,431,581...58,463,437
Ensembl chr 9:58,431,581...58,462,720

G

CD300 molecule like family member F

decreases expression

beta-Naphthoflavone results in decreased expression of CD300LF mRNA

NCBI chr11:115,007,040...115,024,834
Ensembl chr11:115,007,040...115,024,818

G

CD36 molecule

increases expression

beta-Naphthoflavone results in increased expression of CD36 mRNA

NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799

G

CD38 antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD38 mRNA

NCBI chr 5:44,026,153...44,069,714
Ensembl chr 5:44,025,895...44,069,717

G

CD47 antigen (Rh-related antigen, integrin-associated signal transducer)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CD47 mRNA

NCBI chr16:49,671,691...49,732,799
Ensembl chr16:49,620,896...49,735,373

G

CD48 antigen

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD48 mRNA
beta-Naphthoflavone results in decreased expression of CD48 mRNA

PMID:18164116 PMID:32858204

NCBI chr 1:171,508,989...171,532,825
Ensembl chr 1:171,509,577...171,532,826

G

CD52 antigen

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD52 mRNA
beta-Naphthoflavone results in decreased expression of CD52 mRNA

PMID:18164116 PMID:32858204

NCBI chr 4:133,820,849...133,822,384
Ensembl chr 4:133,809,759...133,822,393

G

CD63 antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD63 mRNA

NCBI chr10:128,731,577...128,748,691
Ensembl chr10:128,736,858...128,748,691

G

CD86 antigen

decreases expression

beta-Naphthoflavone results in decreased expression of CD86 mRNA

NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443

G

CD9 antigen

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CD9 mRNA

NCBI chr 6:125,437,229...125,471,723
Ensembl chr 6:125,437,229...125,471,754

G

cell division cycle 20

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDC20 mRNA
beta-Naphthoflavone results in decreased expression of CDC20 mRNA

PMID:18164116 PMID:21295105 PMID:32858204

NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549

G

CDC42 binding protein kinase alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDC42BPA mRNA

NCBI chr 1:179,787,058...179,993,171
Ensembl chr 1:179,788,037...179,993,168

G

CDC42 effector protein 2

increases expression

beta-Naphthoflavone results in increased expression of CDC42EP2 mRNA

NCBI chr19:5,967,584...5,974,844
Ensembl chr19:5,965,664...5,974,844

G

cell division cycle associated 5

affects expression

beta-Naphthoflavone affects the expression of CDCA5 mRNA

NCBI chr19:6,135,127...6,141,803
Ensembl chr19:6,135,013...6,141,807

G

cell division cycle associated 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDCA8 mRNA

NCBI chr 4:124,812,258...124,830,710
Ensembl chr 4:124,812,258...124,833,104

G

cadherin 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH11 mRNA

NCBI chr 8:103,358,727...103,512,125
Ensembl chr 8:103,358,727...103,512,274

G

cadherin 13

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH13 mRNA

NCBI chr 8:119,010,150...120,051,668
Ensembl chr 8:119,010,472...120,051,660

G

cadherin 17

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDH17 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CDH17 mRNA

PMID:18164116 PMID:19737545

NCBI chr 4:11,758,157...11,817,905
Ensembl chr 4:11,758,147...11,817,895

G

cadherin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDH3 mRNA

NCBI chr 8:107,237,484...107,283,543
Ensembl chr 8:107,237,523...107,283,929

G

cadherin-related family member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDHR5 mRNA

NCBI chr 7:140,848,993...140,856,708
Ensembl chr 7:140,848,996...140,856,699

G

cyclin dependent kinase 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDK1 mRNA
beta-Naphthoflavone results in decreased expression of CDK1 mRNA

PMID:18164116 PMID:32858204

NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768

G

cyclin dependent kinase 13

increases expression

beta-Naphthoflavone results in increased expression of CDK13 mRNA

NCBI chr13:17,885,309...17,979,960
Ensembl chr13:17,884,900...17,979,682

G

CDK5 regulatory subunit associated protein 2

increases expression

beta-Naphthoflavone results in increased expression of CDK5RAP2 mRNA

NCBI chr 4:70,135,092...70,328,672
Ensembl chr 4:70,135,093...70,328,680

G

cyclin dependent kinase inhibitor 1A

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CDKN1A mRNA; beta-Naphthoflavone results in decreased expression of CDKN1A protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDKN1A mRNA

PMID:18164116 PMID:19389873 PMID:22687991

NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701

G

cyclin dependent kinase inhibitor 1C

decreases expression

beta-Naphthoflavone results in decreased expression of CDKN1C mRNA

NCBI chr 7:143,012,076...143,014,735
Ensembl chr 7:143,012,076...143,014,787

G

cyclin dependent kinase inhibitor 2B

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CDKN2B mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDKN2B mRNA]

PMID:21295105 PMID:22687991

NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276

G

cysteine dioxygenase 1, cytosolic

decreases expression

beta-Naphthoflavone results in decreased expression of CDO1 mRNA

NCBI chr18:46,846,260...46,861,569
Ensembl chr18:46,846,260...46,861,462

G

cerebellar degeneration-related 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CDR2 mRNA

NCBI chr 7:120,556,259...120,581,535
Ensembl chr 7:120,556,259...120,581,535

G

caudal type homeobox 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CDX2 mRNA

NCBI chr 5:147,237,710...147,244,059
Ensembl chr 5:147,237,615...147,244,080

G

CEA cell adhesion molecule 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CEACAM1 mRNA

NCBI chr 7:25,161,127...25,177,072
Ensembl chr 7:25,161,132...25,177,028

G

CCAAT/enhancer binding protein alpha

decreases expression

beta-Naphthoflavone results in decreased expression of CEBPA mRNA; beta-Naphthoflavone results in decreased expression of CEBPA protein

NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353

G

chymotrypsin-like elastase family, member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELA1 mRNA

NCBI chr15:100,572,303...100,585,801
Ensembl chr15:100,572,302...100,585,802

G

cadherin, EGF LAG seven-pass G-type receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CELSR1 mRNA

NCBI chr15:85,782,959...85,918,424
Ensembl chr15:85,783,130...85,918,404

G

centromere protein I

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CENPI mRNA

NCBI chr X:133,206,777...133,263,853
Ensembl chr X:133,208,833...133,263,388

G

centromere protein X

increases expression

beta-Naphthoflavone results in increased expression of CENPX mRNA

NCBI chr11:120,601,768...120,604,721
Ensembl chr11:120,601,768...120,604,564

G

carboxylesterase 1D

increases expression

beta-Naphthoflavone results in increased expression of CES1 mRNA

NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466

G

carboxylesterase 1F

decreases expression

beta-Naphthoflavone results in decreased expression of CES1F mRNA

NCBI chr 8:93,982,864...94,006,394
Ensembl chr 8:93,982,864...94,006,375

G

carboxylesterase 2E

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CES2E mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES2E mRNA]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CES2E mRNA

PMID:18164116 PMID:22234961

NCBI chr 8:105,652,892...105,661,304
Ensembl chr 8:105,652,892...105,661,304

G

carboxylesterase 3A

decreases expression

beta-Naphthoflavone results in decreased expression of CES3A mRNA

NCBI chr 8:105,775,208...105,788,560
Ensembl chr 8:105,775,233...105,785,045

G

carboxylesterase 3B

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CES3 mRNA; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CES3 mRNA]

PMID:19737545 PMID:22234961

NCBI chr 8:105,810,365...105,820,561
Ensembl chr 8:105,810,385...105,820,561

G

centrin 4

increases expression

beta-Naphthoflavone results in increased expression of CETN4 mRNA

NCBI chr 3:37,362,776...37,366,595
Ensembl chr 3:37,361,898...37,366,857

G

cilia and flagella associated protein 45

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFAP45 mRNA

NCBI chr 1:172,348,697...172,373,437
Ensembl chr 1:172,348,368...172,373,437

G

craniofacial development protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CFDP1 mRNA

NCBI chr 8:112,493,314...112,580,969
Ensembl chr 8:112,495,123...112,580,923

G

cholesterol 25-hydroxylase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CH25H mRNA

NCBI chr19:34,451,183...34,452,548
Ensembl chr19:34,451,178...34,452,564

G

coiled-coil-helix-coiled-coil-helix domain containing 6

decreases expression

beta-Naphthoflavone results in decreased expression of CHCHD6 mRNA

NCBI chr 6:89,360,128...89,572,634
Ensembl chr 6:89,360,128...89,572,634

G

choline dehydrogenase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHDH mRNA

NCBI chr14:29,730,957...29,762,423
Ensembl chr14:29,730,980...29,762,484

G

chondroitin polymerizing factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHPF mRNA

NCBI chr 1:75,451,213...75,456,115
Ensembl chr 1:75,451,213...75,455,951

G

cholinergic receptor nicotinic beta 1 subunit

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CHRNB1 mRNA

NCBI chr11:69,674,862...69,686,742
Ensembl chr11:69,674,862...69,686,769

G

chondroitin sulfate synthase 1

decreases expression

beta-Naphthoflavone results in decreased expression of CHSY1 mRNA

NCBI chr 7:65,759,240...65,823,546
Ensembl chr 7:65,759,263...65,823,546

G

cytokine inducible SH2-containing protein

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CISH mRNA

NCBI chr 9:107,173,858...107,179,983
Ensembl chr 9:107,173,225...107,179,983

G

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CITED2 mRNA

NCBI chr10:17,598,452...17,601,422
Ensembl chr10:17,598,966...17,601,422

G

CDC28 protein kinase 1b

decreases expression

beta-Naphthoflavone results in decreased expression of CKS1B mRNA

NCBI chr 3:89,322,779...89,325,598
Ensembl chr 3:89,322,779...89,325,690

G

chloride channel, voltage-sensitive 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLCN5 mRNA

NCBI chr X:7,020,049...7,185,597
Ensembl chr X:7,020,049...7,185,597

G

claudin 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLDN1 mRNA
beta-Naphthoflavone results in increased expression of CLDN1 mRNA

PMID:18164116 PMID:32151702

NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591

G

claudin 4

increases expression

beta-Naphthoflavone results in increased expression of CLDN4 mRNA

NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788

G

claudin 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CLDN7 mRNA

NCBI chr11:69,855,605...69,858,712
Ensembl chr11:69,855,605...69,858,711

G

C-type lectin domain family 12, member a

decreases expression

beta-Naphthoflavone results in decreased expression of CLEC12A mRNA

NCBI chr 6:129,327,207...129,342,266
Ensembl chr 6:129,319,654...129,342,266

G

C-type lectin domain family 1, member a

decreases expression

beta-Naphthoflavone results in decreased expression of CLEC1A mRNA

NCBI chr 6:129,403,647...129,428,963
Ensembl chr 6:129,401,735...129,428,963

G

chloride intracellular channel 1

increases expression

beta-Naphthoflavone results in increased expression of CLIC1 mRNA

NCBI chr17:35,269,219...35,277,695
Ensembl chr17:35,268,942...35,277,725

G

clock circadian regulator

multiple interactions

beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to BMAL1 protein]; beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to PER1 promoter]

NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639

G

caseinolytic mitochondrial matrix peptidase chaperone subunit

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLPX mRNA

NCBI chr 9:65,201,533...65,237,940
Ensembl chr 9:65,201,542...65,237,940

G

citrate lyase beta like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CLYBL mRNA

NCBI chr14:122,408,289...122,639,646
Ensembl chr14:122,419,116...122,639,646

G

cornifelin

increases expression

beta-Naphthoflavone results in increased expression of CNFN mRNA

NCBI chr 7:25,067,041...25,069,149
Ensembl chr 7:25,067,045...25,069,149

G

calponin 2

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CNN2 mRNA

NCBI chr10:79,824,434...79,831,234
Ensembl chr10:79,824,418...79,831,896

G

calponin 3, acidic

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNN3 mRNA

NCBI chr 3:121,220,190...121,251,854
Ensembl chr 3:121,220,146...121,251,856

G

2',3'-cyclic nucleotide 3' phosphodiesterase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CNP1 mRNA

NCBI chr11:100,465,765...100,472,565
Ensembl chr11:100,465,730...100,482,555

G

collagen, type XVI, alpha 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL16A1 mRNA

NCBI chr 4:129,941,638...129,993,070
Ensembl chr 4:129,941,633...129,993,076

G

collagen, type XVII, alpha 1

decreases expression

beta-Naphthoflavone results in decreased expression of COL17A1 mRNA

NCBI chr19:47,634,783...47,680,460
Ensembl chr19:47,634,783...47,680,533

G

collagen, type XVIII, alpha 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL18A1 mRNA

NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382

G

collagen, type I, alpha 1

multiple interactions
affects expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL1A1 mRNA
beta-Naphthoflavone affects the expression of COL1A1 mRNA

PMID:18164116 PMID:20045035 PMID:21295105 PMID:23994337

NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868

G

collagen, type XXII, alpha 1

decreases expression

beta-Naphthoflavone results in decreased expression of COL22A1 mRNA

NCBI chr15:71,667,644...71,906,087
Ensembl chr15:71,667,644...71,906,076

G

collagen, type XXVII, alpha 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL27A1 mRNA

NCBI chr 4:63,132,246...63,253,228
Ensembl chr 4:63,132,241...63,253,228

G

collagen, type IV, alpha 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL4A1 mRNA

NCBI chr 8:11,248,423...11,362,889
Ensembl chr 8:11,248,423...11,362,826

G

collagen, type V, alpha 1

decreases expression

beta-Naphthoflavone results in decreased expression of COL5A1 mRNA

NCBI chr 2:27,776,393...27,929,522
Ensembl chr 2:27,776,437...27,929,526

G

collagen, type VI, alpha 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COL6A2 mRNA

NCBI chr10:76,431,590...76,459,464
Ensembl chr10:76,431,596...76,459,464

G

collectin sub-family member 12

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of COLEC12 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COLEC12 mRNA

PMID:18164116 PMID:19737606

NCBI chr18:9,707,648...9,877,995
Ensembl chr18:9,707,595...9,882,644

G

coenzyme Q10B

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of COQ10B mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of COQ10B mRNA]

NCBI chr 1:55,091,929...55,111,861
Ensembl chr 1:55,091,929...55,111,861

G

coenzyme Q8A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of COQ8A mRNA

NCBI chr 1:179,992,803...180,023,585
Ensembl chr 1:179,992,803...180,027,167

G

cytochrome c oxidase subunit 6B2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of COX6B2 mRNA

NCBI chr 7:4,754,791...4,756,093
Ensembl chr 7:4,754,791...4,756,093

G

carboxypeptidase E

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPE mRNA

NCBI chr 8:65,045,576...65,146,143
Ensembl chr 8:65,045,576...65,146,088

G

coproporphyrinogen oxidase

increases expression

beta-Naphthoflavone results in increased expression of CPOX mRNA

NCBI chr16:58,490,571...58,500,754
Ensembl chr16:58,490,655...58,537,999

G

carboxypeptidase Z

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CPZ mRNA

NCBI chr 5:35,659,562...35,682,970
Ensembl chr 5:35,659,562...35,683,042

G

capping protein inhibiting regulator of actin like

decreases expression

beta-Naphthoflavone results in decreased expression of CRACDL mRNA

NCBI chr 1:37,650,758...37,758,905
Ensembl chr 1:37,650,758...37,759,166

G

carnitine acetyltransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRAT mRNA

NCBI chr 2:30,290,483...30,305,602
Ensembl chr 2:30,290,483...30,305,825

G

cysteine-rich C-terminal 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CRCT1 mRNA

NCBI chr 3:92,921,512...92,922,993
Ensembl chr 3:92,921,512...92,922,994

G

cAMP responsive element binding protein 1

increases expression

beta-Naphthoflavone results in increased expression of CREB1 mRNA

NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707

G

cAMP responsive element binding protein 5

decreases expression

beta-Naphthoflavone results in decreased expression of CREB5 mRNA

NCBI chr 6:53,264,154...53,677,349
Ensembl chr 6:53,264,255...53,677,361

G

cAMP responsive element modulator

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CREM mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CREM mRNA

PMID:18164116 PMID:19737606

NCBI chr18:3,263,181...3,337,688
Ensembl chr18:3,266,048...3,337,748

G

corticotropin releasing hormone

decreases expression

beta-Naphthoflavone results in decreased expression of CRH mRNA

NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560

G

cysteine rich protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CRIP2 mRNA

NCBI chr12:113,103,856...113,109,126
Ensembl chr12:113,103,856...113,109,126

G

cysteine-rich secretory protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CRISP2 mRNA

NCBI chr17:41,075,625...41,105,037
Ensembl chr17:41,074,911...41,117,894

G

carnitine O-octanoyltransferase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CROT mRNA

NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324

G

crystallin, alpha B

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CRYAB mRNA
beta-Naphthoflavone results in decreased expression of CRYAB mRNA

PMID:18164116 PMID:32858204

NCBI chr 9:50,657,251...50,667,936
Ensembl chr 9:50,662,625...50,667,936

G

crystallin, zeta

multiple interactions
increases activity
increases expression

AHR protein promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased activity of CRYZ protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CRYZ mRNA]

NCBI chr 3:154,302,348...154,328,819
Ensembl chr 3:154,302,348...154,328,819

G

colony stimulating factor 1 receptor

decreases expression

beta-Naphthoflavone results in decreased expression of CSF1R mRNA

NCBI chr18:61,238,644...61,264,211
Ensembl chr18:61,233,670...61,265,221

G

colony stimulating factor 3 receptor

decreases expression

beta-Naphthoflavone results in decreased expression of CSF3R mRNA

NCBI chr 4:125,917,241...125,938,233
Ensembl chr 4:125,918,343...125,938,233

G

CUB and Sushi multiple domains 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CSMD1 mRNA

NCBI chr 8:15,942,538...17,586,908
Ensembl chr 8:15,942,537...17,585,602

G

casein beta

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CSN2 mRNA; beta-Naphthoflavone results in decreased expression of CSN2 protein
AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of CSN2 mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CSN2 mRNA]

NCBI chr 5:87,840,478...87,847,288
Ensembl chr 5:87,840,483...87,847,489

G

cysteine and glycine-rich protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CSRP2 mRNA

NCBI chr10:110,756,037...110,775,375
Ensembl chr10:110,755,650...110,775,483

G

catenin beta 1

multiple interactions

CTNNB1 gene mutant form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CTNNB1 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]

NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573

G

cathepsin C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CTSC mRNA

NCBI chr 7:87,927,233...87,960,083
Ensembl chr 7:87,927,293...87,960,096

G

cullin 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CUL5 mRNA

NCBI chr 9:53,525,881...53,578,807
Ensembl chr 9:53,525,882...53,581,314

G

C-X3-C motif chemokine ligand 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CX3CL1 mRNA

NCBI chr 8:95,498,808...95,509,055
Ensembl chr 8:95,498,637...95,509,055

G

C-X-C motif chemokine ligand 1

increases expression

beta-Naphthoflavone results in increased expression of CXCL1 mRNA

NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974

G

C-X-C motif chemokine ligand 10

decreases expression

beta-Naphthoflavone results in decreased expression of CXCL10 mRNA

NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748

G

chemokine (C-X-C motif) ligand 11

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CXCL11 mRNA
beta-Naphthoflavone results in increased expression of CXCL11 mRNA

PMID:18164116 PMID:32151702

NCBI chr 5:92,507,403...92,511,155
Ensembl chr 5:92,507,403...92,513,344

G

C-X-C motif chemokine ligand 12

decreases expression

beta-Naphthoflavone results in decreased expression of CXCL12 mRNA

NCBI chr 6:117,145,496...117,158,329
Ensembl chr 6:117,145,496...117,158,328

G

C-X-C motif chemokine ligand 13

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CXCL13 mRNA

NCBI chr 5:96,104,785...96,108,927
Ensembl chr 5:96,104,810...96,108,927

G

C-X-C motif chemokine ligand 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CXCL16 mRNA

NCBI chr11:70,345,215...70,350,810
Ensembl chr11:70,344,809...70,350,810

G

C-X-C motif chemokine ligand 2

increases expression

beta-Naphthoflavone results in increased expression of CXCL2 mRNA

NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797

G

C-X-C motif chemokine ligand 3

increases expression

beta-Naphthoflavone results in increased expression of CXCL1 mRNA

NCBI chr 5:90,933,960...90,935,952
Ensembl chr 5:90,933,962...90,937,459

G

C-X-C motif chemokine ligand 5

multiple interactions
increases expression

IL1B protein promotes the reaction [beta-Naphthoflavone results in increased expression of CXCL5 mRNA]

NCBI chr 5:90,907,157...90,909,484
Ensembl chr 5:90,907,219...90,909,483

G

C-X-C motif chemokine receptor 6

decreases expression

beta-Naphthoflavone results in decreased expression of CXCR6 mRNA

NCBI chr 9:123,635,542...123,640,819
Ensembl chr 9:123,635,540...123,640,825

G

cytochrome b5 type B

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of CYB5B mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYB5B mRNA]

NCBI chr 8:107,877,293...107,914,102
Ensembl chr 8:107,877,272...107,914,103

G

cytochrome b5 reductase 2

increases expression

beta-Naphthoflavone results in increased expression of CYB5R2 mRNA

NCBI chr 7:107,347,653...107,357,407
Ensembl chr 7:107,347,662...107,357,239

G

cytoplasmic FMR1 interacting protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of CYFIP2 mRNA

NCBI chr11:46,084,676...46,203,686
Ensembl chr11:46,084,677...46,203,686

G

cytoglobin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYGB mRNA

NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139

G

cytochrome P450, family 11, subfamily a, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP11A1 mRNA

NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CYP17A1 mRNA

NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611

G

cytochrome P450, family 19, subfamily a, polypeptide 1

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of CYP19A1 mRNA
beta-Naphthoflavone results in decreased expression of CYP19A1 mRNA

PMID:19737606 PMID:32858204

NCBI chr 9:54,073,221...54,175,448
Ensembl chr 9:54,073,221...54,175,394

G

cytochrome P450, family 1, subfamily a, polypeptide 1

decreases activity
increases activity
increases expression
multiple interactions

beta-Naphthoflavone results in decreased activity of CYP1A1 protein
beta-Naphthoflavone results in increased activity of CYP1A1 promoter; beta-Naphthoflavone results in increased activity of CYP1A1 protein
beta-Naphthoflavone results in increased expression of CYP1A1; beta-Naphthoflavone results in increased expression of CYP1A1 mRNA; beta-Naphthoflavone results in increased expression of CYP1A1 protein
3'-methoxy-4'-nitroflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Resveratrol results in increased expression of CYP1A1 protein]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A1 protein; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]; Resveratrol inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [beta-Naphthoflavone binds to and affects the localization of AHR protein] promotes the reaction [[AHR protein binds to CYP1A1 enhancer] which results in increased expression of CYP1A1 mRNA]; [beta-Naphthoflavone binds to and affects the localization of AHR protein] which results in increased expression of CYP1A1 mRNA; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of NQO1 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; Acetylcysteine affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Acetylcysteine affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [beta-Naphthoflavone results in decreased activity of CYP1A1 protein]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR gene alternative form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Apigenin promotes the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; ARNT affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Arsenic inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Arsenic promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Ascorbic Acid affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Ascorbic Acid affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Berberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; beta-Naphthoflavone promotes the reaction [14-deoxy-11,12-didehydroandrographolide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [andrographolide results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A1 protein]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 protein]; Buthionine Sulfoximine promotes the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Buthionine Sulfoximine promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Butylated Hydroxytoluene affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Cadmium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Cadmium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Cadmium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Chromium promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; chrysin promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; CTNNB1 gene mutant form affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A1 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; FH535 inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; flavanone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; galangin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Glutathione affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Glutathione affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Hydrogen Peroxide promotes the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Hydrogen Peroxide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; kaempferol inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Lead inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Luteolin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; morin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; naringenin promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; neoandrographolide inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Sorafenib inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; AHR protein promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Amiodarone promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A1 protein; Curcumin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Drugs, Chinese Herbal inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Genistein inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]; Quercetin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Resveratrol inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Silymarin inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]; Tamoxifen inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A1 protein]

PMID:1358564 PMID:2154339 PMID:3379039 PMID:3929785 PMID:7646562 More...

NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions
decreases activity
increases activity
increases expression
increases response to substance

beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone promotes the reaction [CYP1A2 protein affects the metabolism of Thiabendazole]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A1 mRNA]]; CYP1A2 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 protein]]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]; CYP1A2 gene mutant form promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]
beta-Naphthoflavone results in decreased activity of CYP1A2 protein
beta-Naphthoflavone results in increased activity of CYP1A2 protein
[2-amino-3,8-dimethylimidazo(4,5-f)quinoxaline co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 protein; beta-Naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; beta-Naphthoflavone results in increased expression of and results in increased activity of CYP1A2 protein; diphenyleneiodonium inhibits the reaction [beta-Naphthoflavone results in increased activity of CYP1A2 protein]; lead nitrate inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]
beta-Naphthoflavone results in increased expression of CYP1A2 mRNA; beta-Naphthoflavone results in increased expression of CYP1A2 protein
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of CYP1A2 protein] which results in decreased susceptibility to Oxygen; [furafylline results in decreased activity of CYP1A2 protein] promotes the reaction [beta-Naphthoflavone results in increased activity of AHR protein]; Berberine inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased activity of CYP1A2 protein]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of CYP1A2 mRNA]; CTNNB1 gene mutant form inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; CYP1A2 protein affects the reaction [beta-Naphthoflavone results in increased metabolism of Imiquimod]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A2 mRNA]
CYP1A2 gene mutant form results in increased susceptibility to beta-Naphthoflavone

PMID:2208584 PMID:3038308 PMID:8419313 PMID:8902619 PMID:10463385 More...

NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions
increases expression

beta-Naphthoflavone binds to and results in decreased activity of CYP1B1 protein
andrographolide promotes the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]; Apigenin affects the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]; Pregnenolone Carbonitrile inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1B1 mRNA]
beta-Naphthoflavone results in increased expression of CYP1B1 mRNA; beta-Naphthoflavone results in increased expression of CYP1B1 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1B1 mRNA
beta-Naphthoflavone results in increased expression of CYP1B1; beta-Naphthoflavone results in increased expression of CYP1B1 mRNA

PMID:12623754 PMID:14990334 PMID:16985168 PMID:18164116 PMID:19389873 More...

NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490

G

cytochrome P450, family 26, subfamily a, polypeptide 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP26A1 mRNA

NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP27A1 mRNA

NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051

G

cytochrome P450, family 27, subfamily b, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP27B1 mRNA

NCBI chr10:126,884,115...126,891,897
Ensembl chr10:126,884,119...126,888,875

G

cytochrome P450, family 2, subfamily a, polypeptide 12

increases expression

beta-Naphthoflavone results in increased expression of CYP2A12 mRNA

NCBI chr 7:26,728,515...26,736,243
Ensembl chr 7:26,728,506...26,736,800

G

cytochrome P450, family 2, subfamily a, polypeptide 22

increases expression

beta-Naphthoflavone results in increased expression of CYP2A1 mRNA

NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809

G

cytochrome P450, family 2, subfamily a, polypeptide 4

multiple interactions

beta-Naphthoflavone promotes the reaction [andrographolide results in increased expression of CYP2A4 mRNA]

NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513

G

cytochrome P450, family 2, subfamily a, polypeptide 5

increases expression

beta-Naphthoflavone results in increased expression of CYP2A5 mRNA
beta-Naphthoflavone results in increased expression of CYP2A6 mRNA

PMID:19118567 PMID:29788535

NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973

G

cytochrome P450, family 2, subfamily b, polypeptide 10

multiple interactions
increases expression
increases activity

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP2B10 mRNA
beta-Naphthoflavone results in increased expression of CYP2B6 mRNA
beta-Naphthoflavone results in increased activity of CYP2B6 protein

PMID:19118567 PMID:19497361 PMID:19737545 PMID:22258563

NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049

G

cytochrome P450, family 2, subfamily b, polypeptide 13

multiple interactions
decreases expression
increases activity

beta-Naphthoflavone inhibits the reaction [9,10-Dimethyl-1,2-benzanthracene results in increased activity of CYP2B2 protein]
beta-Naphthoflavone results in decreased expression of CYP2B2 mRNA
beta-Naphthoflavone results in increased activity of CYP2B2 protein

PMID:16054776 PMID:20607812

NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622

G

cytochrome P450, family 2, subfamily b, polypeptide 9

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP2B9 mRNA
beta-Naphthoflavone results in increased expression of CYP2B9 mRNA

NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086

G

cytochrome P450, family 2, subfamily c, polypeptide 29

multiple interactions

[Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of CYP2C6 protein

NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157

G

cytochrome P450, family 2, subfamily c, polypeptide 38

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2C19 mRNA

PMID:16985168 PMID:33263786

NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519

G

cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2C11 protein
beta-Naphthoflavone results in decreased expression of CYP2C18 mRNA

PMID:16985168 PMID:18164116 PMID:30842367

NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733

G

cytochrome P450, family 2, subfamily c, polypeptide 65

multiple interactions
decreases expression

beta-Naphthoflavone inhibits the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen]
beta-Naphthoflavone results in decreased expression of CYP2C9 mRNA

PMID:16985168 PMID:21053930 PMID:33263786

NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388

G

cytochrome P450, family 2, subfamily d, polypeptide 22

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2D6 mRNA

NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461

G

cytochrome P450, family 2, subfamily e, polypeptide 1

increases expression
decreases expression
multiple interactions

beta-Naphthoflavone results in increased expression of CYP2E1 mRNA
beta-Naphthoflavone results in decreased expression of CYP2E1 mRNA
[Phenobarbital co-treated with beta-Naphthoflavone] results in decreased expression of CYP2E1 protein
beta-Naphthoflavone results in increased expression of CYP2E1 mRNA; beta-Naphthoflavone results in increased expression of CYP2E1 protein
[CYP2E1 protein co-treated with beta-Naphthoflavone] results in increased expression of KLF6 protein

PMID:19969063 PMID:22258563 PMID:22486562 PMID:30373287 PMID:30842367

NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900

G

cytochrome P450, family 2, subfamily j, polypeptide 9

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2J2 mRNA

NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815

G

cytochrome P450, family 2, subfamily s, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP2S1 mRNA

NCBI chr 7:25,501,894...25,515,950
Ensembl chr 7:25,501,900...25,516,338

G

cytochrome P450, family 2, subfamily u, polypeptide 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP2U1 mRNA

NCBI chr 3:131,084,140...131,097,806
Ensembl chr 3:131,082,090...131,096,876

G

cytochrome P450, family 2, subfamily w, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP2W1 mRNA

NCBI chr 5:139,338,371...139,345,362
Ensembl chr 5:139,338,372...139,342,788

G

cytochrome P450, family 3, subfamily a, polypeptide 11

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of CYP3A11 mRNA
beta-Naphthoflavone results in decreased expression of CYP3A11 mRNA

PMID:17627975 PMID:19737545

NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774

G

cytochrome P450, family 3, subfamily a, polypeptide 13

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of CYP3A13 mRNA
beta-Naphthoflavone results in decreased expression of CYP3A7 mRNA
beta-Naphthoflavone results in decreased expression of CYP3A5 mRNA

PMID:18164116 PMID:22258563 PMID:33263786

NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881

G

cytochrome P450, family 4, subfamily a, polypeptide 12B

increases expression

beta-Naphthoflavone results in increased expression of CYP4A1 mRNA

NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231

G

cytochrome P450, family 4, subfamily a, polypeptide 14

decreases expression

beta-Naphthoflavone results in decreased expression of CYP4A14 mRNA

NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339

G

cytochrome P450, family 4, subfamily b, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP4B1 mRNA

PMID:16985168 PMID:22258563

NCBI chr 4:115,481,895...115,504,918
Ensembl chr 4:115,481,922...115,504,920

G

cytochrome P450, family 4, subfamily f, polypeptide 18

increases expression

beta-Naphthoflavone results in increased expression of CYP4F3 mRNA

NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470

G

cytochrome P450, family 51

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP51 mRNA
beta-Naphthoflavone results in decreased expression of CYP51 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of CYP51 mRNA]

PMID:18164116 PMID:22234961

NCBI chr 5:4,130,674...4,154,697
Ensembl chr 5:4,131,145...4,154,746

G

cytochrome P450, family 7, subfamily a, polypeptide 1

decreases expression

beta-Naphthoflavone results in decreased expression of CYP7A1 mRNA

NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633

G

cytochrome P450, family 7, subfamily b, polypeptide 1

increases expression

beta-Naphthoflavone results in increased expression of CYP7B1 mRNA

NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502

G

drebrin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBN1 mRNA

NCBI chr13:55,621,241...55,635,874
Ensembl chr13:55,621,242...55,635,924

G

D site albumin promoter binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DBP mRNA

NCBI chr 7:45,354,658...45,359,579
Ensembl chr 7:45,354,512...45,359,627

G

doublecortin-like kinase 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DCLK1 mRNA
beta-Naphthoflavone results in increased expression of DCLK1 mRNA

PMID:18164116 PMID:23994337

NCBI chr 3:55,149,724...55,446,489
Ensembl chr 3:55,149,785...55,446,489

G

decorin

decreases expression

beta-Naphthoflavone results in decreased expression of DCN mRNA

NCBI chr10:97,315,362...97,354,025
Ensembl chr10:97,315,471...97,354,005

G

defective in cullin neddylation 1 domain containing 1

increases expression

beta-Naphthoflavone results in increased expression of DCUN1D1 mRNA

NCBI chr 3:35,946,254...35,991,626
Ensembl chr 3:35,946,254...35,991,594

G

dopa decarboxylase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of DDC mRNA

NCBI chr11:11,764,101...11,848,144
Ensembl chr11:11,764,101...11,848,144

G

DNA-damage-inducible transcript 4

increases expression

beta-Naphthoflavone results in increased expression of DDIT4 mRNA

NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656

G

defensin, alpha, 3

increases expression

beta-Naphthoflavone results in increased expression of DEFA3 mRNA

NCBI chr 8:21,777,425...21,778,393
Ensembl chr 8:21,777,425...21,778,393

G

defensin beta 1

decreases expression

beta-Naphthoflavone results in decreased expression of DEFB1 mRNA

NCBI chr 8:22,266,571...22,285,201
Ensembl chr 8:22,266,615...22,285,201

G

defensin beta 14

increases expression

beta-Naphthoflavone results in increased expression of DEFB103A mRNA

NCBI chr 8:19,213,172...19,245,342
Ensembl chr 8:19,244,373...19,245,228

G

DENN domain containing 2A

decreases expression

beta-Naphthoflavone results in decreased expression of DENND2A mRNA

NCBI chr 6:39,439,308...39,535,067
Ensembl chr 6:39,439,312...39,534,801

G

DEP domain containing 1B

decreases expression

beta-Naphthoflavone results in decreased expression of DEPDC1B mRNA

NCBI chr13:108,452,592...108,526,100
Ensembl chr13:108,452,866...108,544,316

G

DEPP1 autophagy regulator

increases expression

beta-Naphthoflavone results in increased expression of DEPP1 mRNA

NCBI chr 6:116,627,645...116,629,808
Ensembl chr 6:116,627,570...116,629,755

G

dexamethasone-induced transcript

decreases expression

beta-Naphthoflavone results in decreased expression of DEXI mRNA

NCBI chr16:10,348,071...10,360,918
Ensembl chr16:10,320,395...10,360,918

G

diacylglycerol O-acyltransferase 2

decreases expression

beta-Naphthoflavone results in decreased expression of DGAT2 mRNA

NCBI chr 7:98,802,870...98,831,920
Ensembl chr 7:98,802,865...98,831,926

G

7-dehydrocholesterol reductase

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DHCR7 mRNA]

NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147

G

dehydrogenase/reductase 9

decreases expression

beta-Naphthoflavone results in decreased expression of DHRS9 mRNA

NCBI chr 2:69,210,806...69,233,430
Ensembl chr 2:69,210,789...69,234,877

G

deiodinase, iodothyronine, type II

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DIO2 mRNA

NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812

G

dickkopf WNT signaling pathway inhibitor 1

decreases expression

beta-Naphthoflavone results in decreased expression of DKK1 mRNA

NCBI chr19:30,523,276...30,526,896
Ensembl chr19:30,523,263...30,527,065

G

deleted in malignant brain tumors 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DMBT1 mRNA

NCBI chr 7:130,633,787...130,723,357
Ensembl chr 7:130,633,776...130,723,357

G

dimethylglycine dehydrogenase precursor

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of DMGDH mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of DMGDH mRNA]

NCBI chr13:93,810,944...93,889,331
Ensembl chr13:93,810,941...93,889,341

G

dynein, axonemal, heavy chain 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DNAH9 mRNA

NCBI chr11:65,722,150...66,059,379
Ensembl chr11:65,722,108...66,059,377

G

DnaJ heat shock protein family (Hsp40) member B11

increases expression

beta-Naphthoflavone results in increased expression of DNAJB11 mRNA

NCBI chr16:22,676,595...22,698,384
Ensembl chr16:22,676,595...22,698,384

G

dynamin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1 mRNA

NCBI chr 2:32,198,483...32,243,361
Ensembl chr 2:32,198,483...32,243,350

G

dynamin 1-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DNM1L mRNA

NCBI chr16:16,130,092...16,176,863
Ensembl chr16:16,130,094...16,176,823

G

DNA methyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of DNMT1 mRNA

NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184

G

dedicator of cytokinesis 9

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DOCK9 mRNA

NCBI chr14:121,772,026...122,038,465
Ensembl chr14:121,779,458...122,035,249

G

dipeptidase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPEP1 mRNA

NCBI chr 8:123,913,069...123,928,551
Ensembl chr 8:123,912,981...123,928,551

G

dipeptidylpeptidase 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DPP7 mRNA

NCBI chr 2:25,242,302...25,246,365
Ensembl chr 2:25,242,288...25,246,371

G

dystrobrevin, beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DTNB mRNA

NCBI chr12:3,622,372...3,834,070
Ensembl chr12:3,622,381...3,831,796

G

dual specificity phosphatase 13B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DUSP13B mRNA

NCBI chr14:21,783,463...21,792,947
Ensembl chr14:21,783,462...21,792,947

G

dual specificity phosphatase 6

increases expression

beta-Naphthoflavone results in increased expression of DUSP6 mRNA

NCBI chr10:99,098,676...99,103,351
Ensembl chr10:99,099,093...99,103,351

G

decapping exoribonuclease

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of DXO mRNA

NCBI chr17:35,055,998...35,058,162
Ensembl chr17:35,055,995...35,058,209

G

dynein cytoplasmic 1 heavy chain 1

increases expression

beta-Naphthoflavone results in increased expression of DYNC1H1 mRNA

NCBI chr12:110,567,829...110,633,378
Ensembl chr12:110,567,886...110,633,379

G

dysferlin

increases expression

beta-Naphthoflavone results in increased expression of DYSF mRNA

NCBI chr 6:83,985,344...84,188,042
Ensembl chr 6:83,985,572...84,188,042

G

DAZ interacting protein 1-like

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of DZIP1L mRNA

NCBI chr 9:99,511,448...99,552,128
Ensembl chr 9:99,511,549...99,551,309

G

Epstein-Barr virus induced gene 3

decreases expression

beta-Naphthoflavone results in decreased expression of EBI3 mRNA

NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022

G

epidermal growth factor-containing fibulin-like extracellular matrix protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of EFEMP1 mRNA

NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743

G

epidermal growth factor-containing fibulin-like extracellular matrix protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EFEMP2 mRNA

NCBI chr19:5,523,974...5,532,548
Ensembl chr19:5,523,982...5,532,545

G

EF hand domain containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of EFHD1 mRNA

NCBI chr 1:87,192,075...87,238,563
Ensembl chr 1:87,192,085...87,238,561

G

egl-9 family hypoxia-inducible factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EGLN3 mRNA

NCBI chr12:54,225,767...54,250,660
Ensembl chr12:54,225,767...54,250,646

G

early growth response 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EGR1 mRNA

NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037

G

EH-domain containing 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD2 mRNA

NCBI chr 7:15,680,883...15,701,402
Ensembl chr 7:15,680,883...15,701,492

G

EH-domain containing 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EHD4 mRNA

NCBI chr 2:119,919,958...119,985,028
Ensembl chr 2:119,919,656...119,985,087

G

EP300 interacting inhibitor of differentiation 3

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of EID3 mRNA
beta-Naphthoflavone results in increased expression of EID3 mRNA

PMID:19737545 PMID:32858204

NCBI chr10:82,702,460...82,703,764
Ensembl chr10:82,702,460...82,703,764

G

elastin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ELN mRNA

NCBI chr 5:134,731,449...134,776,300
Ensembl chr 5:134,731,447...134,776,177

G

ELOVL fatty acid elongase 3

decreases expression

beta-Naphthoflavone results in decreased expression of ELOVL3 mRNA

NCBI chr19:46,120,336...46,124,133
Ensembl chr19:46,120,336...46,124,133

G

ELOVL fatty acid elongase 6

decreases expression

beta-Naphthoflavone results in decreased expression of ELOVL6 mRNA

NCBI chr 3:129,326,035...129,432,144
Ensembl chr 3:129,326,004...129,432,144

G

elastin microfibril interfacer 1

increases expression

beta-Naphthoflavone results in increased expression of EMILIN1 mRNA

NCBI chr 5:31,070,729...31,078,623
Ensembl chr 5:31,070,746...31,078,621

G

epithelial membrane protein 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EMP1 mRNA
beta-Naphthoflavone results in decreased expression of EMP1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 6:135,339,548...135,360,171
Ensembl chr 6:135,339,543...135,360,171

G

epithelial membrane protein 3

increases expression

beta-Naphthoflavone results in increased expression of EMP3 mRNA

NCBI chr 7:45,567,447...45,570,850
Ensembl chr 7:45,567,447...45,570,828

G

empty spiracles homeobox 2

decreases expression

beta-Naphthoflavone results in decreased expression of EMX2 mRNA

NCBI chr19:59,447,122...59,453,789
Ensembl chr19:59,446,804...59,453,789

G

ectodermal-neural cortex 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENC1 mRNA

NCBI chr13:97,377,613...97,389,548
Ensembl chr13:97,377,613...97,389,542

G

ectonucleotide pyrophosphatase/phosphodiesterase 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENPP5 mRNA

NCBI chr17:44,389,693...44,397,458
Ensembl chr17:44,389,704...44,397,458

G

ectonucleoside triphosphate diphosphohydrolase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ENTPD2 mRNA

NCBI chr 2:25,285,886...25,291,335
Ensembl chr 2:25,285,886...25,291,333

G

epithelial cell adhesion molecule

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPCAM mRNA

NCBI chr17:87,943,407...87,958,555
Ensembl chr17:87,943,407...87,958,557

G

ependymin related 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EPDR1 mRNA

NCBI chr13:19,775,878...19,804,000
Ensembl chr13:19,775,876...19,804,097

G

epoxide hydrolase 1, microsomal

decreases activity
increases expression

beta-Naphthoflavone results in decreased activity of EPHX1 protein
beta-Naphthoflavone results in increased expression of EPHX1 mRNA

PMID:3621371 PMID:22258563 PMID:23994337

NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469

G

elongin BC and polycomb repressive complex 2 associated protein

increases expression

beta-Naphthoflavone results in increased expression of EPOP mRNA

NCBI chr11:97,518,213...97,520,542
Ensembl chr11:97,518,215...97,520,528

G

epidermal growth factor receptor pathway substrate 15

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of EPS15 mRNA

NCBI chr 4:109,137,372...109,245,014
Ensembl chr 4:109,137,465...109,245,014

G

erb-b2 receptor tyrosine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of ERBB2 mRNA

NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542

G

endothelial cell-specific adhesion molecule

decreases expression

beta-Naphthoflavone results in decreased expression of ESAM mRNA

NCBI chr 9:37,439,385...37,449,615
Ensembl chr 9:37,439,374...37,449,615

G

endothelial cell-specific molecule 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ESM1 mRNA

NCBI chr13:113,346,193...113,354,638
Ensembl chr13:113,346,193...113,354,632

G

estrogen receptor 1 (alpha)

multiple interactions
affects binding
decreases expression

[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR1 mRNA
[beta-Naphthoflavone binds to AHR protein] which binds to ESR1 protein
beta-Naphthoflavone results in decreased expression of ESR1 mRNA

PMID:10620335 PMID:20607812 PMID:22975028

NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614

G

estrogen receptor 2 (beta)

multiple interactions

[alpha-naphthoflavone co-treated with beta-Naphthoflavone] results in decreased expression of ESR2 mRNA

NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033

G

estrogen related receptor, alpha

affects binding

[beta-Naphthoflavone binds to AHR protein] which binds to ESRRA protein

NCBI chr19:6,888,345...6,899,182
Ensembl chr19:6,888,345...6,899,208

G

ets variant 5

decreases expression

beta-Naphthoflavone results in decreased expression of ETV5 mRNA

NCBI chr16:22,200,063...22,258,320
Ensembl chr16:22,200,059...22,258,469

G

eva-1 homolog A, regulator of programmed cell death

decreases expression

beta-Naphthoflavone results in decreased expression of EVA1A mRNA

NCBI chr 6:82,018,058...82,070,079
Ensembl chr 6:82,018,024...82,070,080

G

ezrin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of EZR mRNA

NCBI chr17:7,005,530...7,050,179
Ensembl chr17:7,005,440...7,050,183

G

coagulation factor V

decreases expression

beta-Naphthoflavone results in decreased expression of F5 mRNA

NCBI chr 1:163,979,396...164,048,539
Ensembl chr 1:163,979,407...164,047,846

G

fatty acid binding protein 4, adipocyte

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FABP4 mRNA

NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636

G

fatty acid desaturase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FADS1 mRNA

NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241

G

family with sequence similarity 43, member A

decreases expression

beta-Naphthoflavone results in decreased expression of FAM43A mRNA

NCBI chr16:30,418,541...30,421,615
Ensembl chr16:30,418,541...30,421,615

G

fatty acyl CoA reductase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FAR1 mRNA

NCBI chr 7:113,113,008...113,170,713
Ensembl chr 7:113,113,041...113,170,718

G

Fas ligand

multiple interactions

AHR mutant form inhibits the reaction [beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]]; beta-Naphthoflavone results in increased activity of [FASLG protein binds to FASLG protein]

NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064

G

fatty acid synthase

decreases expression

beta-Naphthoflavone results in decreased expression of FASN mRNA

NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373

G

filamin binding LIM protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLIM1 mRNA

NCBI chr 4:141,303,373...141,333,351
Ensembl chr 4:141,303,373...141,333,407

G

fibulin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN2 mRNA

NCBI chr 6:91,189,442...91,249,522
Ensembl chr 6:91,189,437...91,249,522

G

fibulin 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FBLN5 mRNA

NCBI chr12:101,712,820...101,785,541
Ensembl chr12:101,712,824...101,785,314

G

fibrillin 2

decreases expression

beta-Naphthoflavone results in decreased expression of FBN2 mRNA

NCBI chr18:58,141,689...58,343,200
Ensembl chr18:58,141,695...58,343,559

G

F-box protein 21

increases expression

beta-Naphthoflavone results in increased expression of FBXO21 mRNA

NCBI chr 5:118,114,835...118,148,263
Ensembl chr 5:118,114,795...118,148,266

G

F-box protein 25

increases expression

beta-Naphthoflavone results in increased expression of FBXO25 mRNA

NCBI chr 8:13,957,667...13,992,862
Ensembl chr 8:13,957,803...13,990,522

G

farnesyl diphosphate farnesyl transferase 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of FDFT1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FDFT1 mRNA]

NCBI chr14:63,382,599...63,419,136
Ensembl chr14:63,382,599...63,417,027

G

farnesyl diphosphate synthetase

decreases expression

beta-Naphthoflavone results in decreased expression of FDPS mRNA

NCBI chr 3:89,000,895...89,009,274
Ensembl chr 3:89,000,895...89,009,266

G

ferredoxin 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of FDX1 mRNA
beta-Naphthoflavone results in decreased expression of FDX1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856

G

fibrinogen beta chain

decreases expression

beta-Naphthoflavone results in decreased expression of FGB mRNA

NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170

G

FYVE, RhoGEF and PH domain containing 5

increases expression

beta-Naphthoflavone results in increased expression of FGD5 mRNA

NCBI chr 6:91,955,809...92,052,986
Ensembl chr 6:91,955,859...92,052,985

G

fibroblast growth factor 21

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of FGF21 mRNA

NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914

G

four and a half LIM domains 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL1 mRNA
beta-Naphthoflavone results in decreased expression of FHL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:55,776,569...55,838,704
Ensembl chr X:55,777,147...55,838,706

G

four and a half LIM domains 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FHL2 mRNA

NCBI chr 1:43,162,233...43,237,501
Ensembl chr 1:43,162,234...43,236,144

G

FK506 binding protein 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FKBP5 mRNA

NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501

G

filaggrin

decreases expression

beta-Naphthoflavone results in decreased expression of FLG protein

NCBI chr 3:93,180,853...93,200,996
Ensembl chr 3:93,180,830...93,200,993

G

filamin C, gamma

increases expression

beta-Naphthoflavone results in increased expression of FLNC mRNA

NCBI chr 6:29,433,150...29,461,888
Ensembl chr 6:29,433,255...29,461,882

G

flavin containing monooxygenase 1

decreases expression

beta-Naphthoflavone results in decreased expression of FMO1 mRNA

NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179

G

flavin containing monooxygenase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FMO2 mRNA

NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295

G

flavin containing monooxygenase 5

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FMO5 mRNA
beta-Naphthoflavone results in decreased expression of FMO5 mRNA

PMID:18164116 PMID:22258563

NCBI chr 3:97,517,248...97,562,603
Ensembl chr 3:97,536,120...97,562,598

G

fibronectin type III domain containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FNDC1 mRNA

NCBI chr17:7,957,401...8,046,158
Ensembl chr17:7,957,401...8,046,134

G

fibronectin type III domain containing 4

increases expression

beta-Naphthoflavone results in increased expression of FNDC4 mRNA

NCBI chr 5:31,449,589...31,453,279
Ensembl chr 5:31,449,586...31,453,424

G

FBJ osteosarcoma oncogene

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FOS mRNA
beta-Naphthoflavone promotes the reaction [FOS protein binds to NQO1 promoter]
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]; beta-Naphthoflavone results in decreased expression of and results in increased ubiquitination of FOS protein; UBE2L3 protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]
beta-Naphthoflavone results in increased expression of FOS mRNA

PMID:8375015 PMID:18164116 PMID:26318284 PMID:32151702

NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047

G

FBJ osteosarcoma oncogene B

increases expression

beta-Naphthoflavone results in increased expression of FOSB mRNA

NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976

G

fos-like antigen 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FOSL1 mRNA

NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974

G

frizzled-related protein

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FRZB mRNA
beta-Naphthoflavone results in decreased expression of FRZB mRNA

PMID:18164116 PMID:32858204

NCBI chr 2:80,242,314...80,277,740
Ensembl chr 2:80,242,314...80,277,969

G

fascin actin-bundling protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of FSCN1 mRNA

NCBI chr 5:142,946,110...142,958,944
Ensembl chr 5:142,946,098...142,958,940

G

follicle stimulating hormone beta

multiple interactions

beta-Naphthoflavone inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]

NCBI chr 2:106,886,331...106,889,996
Ensembl chr 2:106,886,485...106,890,001

G

follistatin-like 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of FSTL1 mRNA
beta-Naphthoflavone results in decreased expression of FSTL1 mRNA

PMID:18164116 PMID:32858204

NCBI chr16:37,597,417...37,656,878
Ensembl chr16:37,597,235...37,656,876

G

G0/G1 switch gene 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of G0S2 mRNA

NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525

G

glucose-6-phosphate dehydrogenase X-linked

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of G6PD protein
beta-Naphthoflavone results in increased expression of G6PD mRNA

PMID:28903497 PMID:32858204

NCBI chr X:73,453,089...73,472,486
Ensembl chr X:73,453,089...73,472,800

G

GABA type A receptor associated protein like 1

increases expression

beta-Naphthoflavone results in increased expression of GABARAPL1 mRNA

NCBI chr 6:129,510,155...129,519,294
Ensembl chr 6:129,510,123...129,519,309

G

gamma-aminobutyric acid type A receptor subunit gamma 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GABRG1 mRNA

NCBI chr 5:70,906,512...70,999,960
Ensembl chr 5:70,908,390...70,999,960

G

growth arrest and DNA-damage-inducible 45 beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GADD45B mRNA

NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038

G

polypeptide N-acetylgalactosaminyltransferase 10

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GALNT10 mRNA

NCBI chr11:57,536,268...57,678,327
Ensembl chr11:57,536,268...57,678,340

G

polypeptide N-acetylgalactosaminyltransferase 18

decreases expression

beta-Naphthoflavone results in decreased expression of GALNT18 mRNA

NCBI chr 7:111,070,863...111,379,274
Ensembl chr 7:111,070,868...111,379,184

G

galanin receptor 2

increases expression

beta-Naphthoflavone results in increased expression of GALR2 mRNA

NCBI chr11:116,170,520...116,174,776
Ensembl chr11:116,171,765...116,174,764

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of GAPDH mRNA

NCBI chr 6:125,138,812...125,143,450
Ensembl chr 6:125,138,678...125,143,430

G

growth arrest specific 1

decreases expression

beta-Naphthoflavone results in decreased expression of GAS1 mRNA

NCBI chr13:60,322,219...60,325,179
Ensembl chr13:60,322,219...60,325,179

G

GATA binding protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GATA3 mRNA

NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845

G

glucosidase beta 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GBA2 mRNA

NCBI chr 4:43,566,928...43,578,893
Ensembl chr 4:43,566,928...43,578,873

G

guanylate-binding protein 9

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of GBP6 mRNA]

NCBI chr 5:105,224,331...105,258,255
Ensembl chr 5:105,225,496...105,287,405

G

glucagon receptor

decreases expression

beta-Naphthoflavone results in decreased expression of GCGR mRNA

NCBI chr11:120,420,011...120,429,815
Ensembl chr11:120,421,525...120,429,812

G

GTP cyclohydrolase I feedback regulator

decreases expression

beta-Naphthoflavone results in decreased expression of GCHFR mRNA

NCBI chr 2:118,998,269...119,002,870
Ensembl chr 2:118,998,254...119,002,871

G

glucokinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GCK mRNA

NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081

G

glutamate-cysteine ligase, catalytic subunit

increases expression

beta-Naphthoflavone results in increased expression of GCLC mRNA

PMID:16426233 PMID:23994337

NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767

G

glutamate-cysteine ligase, modifier subunit

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GCLM mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GCLM mRNA

PMID:19737545 PMID:19737606 PMID:32858204

NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381

G

glial cells missing homolog 1

decreases expression

beta-Naphthoflavone results in decreased expression of GCM1 mRNA

NCBI chr 9:77,959,240...77,972,906
Ensembl chr 9:77,959,206...77,972,906

G

glucosaminyl (N-acetyl) transferase 3, mucin type

increases expression

beta-Naphthoflavone results in increased expression of GCNT3 mRNA

NCBI chr 9:69,938,777...69,947,172
Ensembl chr 9:69,938,778...69,945,370

G

growth differentiation factor 11

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GDF11 mRNA

NCBI chr10:128,716,393...128,727,587
Ensembl chr10:128,718,164...128,727,587

G

growth differentiation factor 15

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of GDF15 mRNA
beta-Naphthoflavone results in decreased expression of GDF15 mRNA

PMID:19737606 PMID:32858204

NCBI chr 8:71,082,043...71,085,106
Ensembl chr 8:71,082,043...71,085,106

G

growth differentiation factor 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GDF6 mRNA

NCBI chr 4:9,844,372...9,862,345
Ensembl chr 4:9,844,372...9,862,345

G

growth factor, augmenter of liver regeneration

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GFER mRNA

NCBI chr17:24,912,164...24,915,065
Ensembl chr17:24,912,161...24,915,503

G

growth hormone

decreases expression

beta-Naphthoflavone results in decreased expression of GH1 mRNA

NCBI chr11:106,191,087...106,194,529
Ensembl chr11:106,191,097...106,192,691

G

gap junction protein, alpha 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GJA5 mRNA

NCBI chr 3:96,939,718...96,960,950
Ensembl chr 3:96,812,009...96,984,732

G

gastrokine 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GKN1 mRNA

NCBI chr 6:87,322,635...87,327,897
Ensembl chr 6:87,322,632...87,327,924

G

galactosidase, alpha

increases expression

beta-Naphthoflavone results in increased expression of GLA mRNA

NCBI chr X:133,488,912...133,501,707
Ensembl chr X:133,488,898...133,501,874

G

gliomedin

decreases expression

beta-Naphthoflavone results in decreased expression of GLDN mRNA

NCBI chr 9:54,193,770...54,249,061
Ensembl chr 9:54,193,770...54,249,070

G

glutaminase 2 (liver, mitochondrial)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GLS2 mRNA

NCBI chr10:128,030,504...128,045,873
Ensembl chr10:128,030,326...128,045,873

G

glutamate-ammonia ligase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GLUL mRNA

NCBI chr 1:153,775,692...153,785,469
Ensembl chr 1:153,775,690...153,785,469

G

predicted gene 13889

decreases expression

beta-Naphthoflavone results in decreased expression of C11ORF96 mRNA

NCBI chr 2:93,786,155...93,787,445
Ensembl chr 2:93,786,155...93,787,546

G

GDP-mannose 4, 6-dehydratase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GMDS mRNA

NCBI chr13:32,003,566...32,522,744
Ensembl chr13:32,003,562...32,522,723

G

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

decreases expression

beta-Naphthoflavone results in decreased expression of GNE mRNA

NCBI chr 4:44,034,075...44,084,177
Ensembl chr 4:44,034,075...44,084,177

G

guanine nucleotide binding protein (G protein), gamma 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GNG8 mRNA

NCBI chr 7:16,625,687...16,629,361
Ensembl chr 7:16,625,711...16,629,361

G

glucosamine-6-phosphate deaminase 1

decreases expression

beta-Naphthoflavone results in decreased expression of GNPDA1 mRNA

NCBI chr18:38,460,588...38,472,052
Ensembl chr18:38,460,588...38,472,056

G

golgin A3

decreases expression

beta-Naphthoflavone results in decreased expression of GOLGA3 mRNA

NCBI chr 5:110,324,723...110,374,336
Ensembl chr 5:110,324,567...110,374,336

G

glycerol-3-phosphate acyltransferase, mitochondrial

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPAM mRNA

NCBI chr19:55,056,067...55,115,666
Ensembl chr19:55,055,700...55,115,670

G

G protein-coupled bile acid receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPBAR1 mRNA

NCBI chr 1:74,316,269...74,318,868
Ensembl chr 1:74,317,709...74,318,783

G

glypican 3

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPC3 mRNA
beta-Naphthoflavone results in decreased expression of GPC3 mRNA

PMID:18164116 PMID:32858204

NCBI chr X:51,361,303...51,702,851
Ensembl chr X:51,361,303...51,702,827

G

glycerol phosphate dehydrogenase 2, mitochondrial

decreases expression

beta-Naphthoflavone results in decreased expression of GPD2 mRNA

NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731

G

glycoprotein m6a

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPM6A mRNA

NCBI chr 8:55,232,469...55,513,913
Ensembl chr 8:55,407,878...55,513,906

G

glycoprotein m6b

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPM6B mRNA

NCBI chr X:165,021,911...165,172,028
Ensembl chr X:165,021,907...165,171,984

G

G protein-coupled receptor 35

increases expression

beta-Naphthoflavone results in increased expression of GPR35 mRNA

NCBI chr 1:92,875,774...92,913,984
Ensembl chr 1:92,878,587...92,914,113

G

G protein-coupled receptor 68

increases expression

beta-Naphthoflavone results in increased expression of GPR68 mRNA

NCBI chr12:100,842,941...100,874,457
Ensembl chr12:100,842,941...100,874,457

G

G protein-coupled receptor, family C, group 5, member C

increases expression

beta-Naphthoflavone results in increased expression of GPRC5C mRNA

NCBI chr11:114,741,976...114,763,443
Ensembl chr11:114,741,978...114,763,443

G

glutamic pyruvic transaminase, soluble

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPT mRNA

NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886

G

glutathione peroxidase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GPX1 mRNA

NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542

G

glutathione peroxidase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GPX2 mRNA; beta-Naphthoflavone results in increased expression of GPX2 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX2 mRNA

PMID:18164116 PMID:19389873 PMID:20045035 PMID:21203749 PMID:22687991

NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273

G

glutathione peroxidase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX3 mRNA

NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203

G

glutathione peroxidase 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GPX6 mRNA

NCBI chr13:21,479,635...21,503,795
Ensembl chr13:21,496,295...21,503,794

G

growth factor receptor bound protein 7

decreases expression

beta-Naphthoflavone results in decreased expression of GRB7 mRNA

NCBI chr11:98,337,660...98,346,199
Ensembl chr11:98,337,220...98,346,199

G

glutamate receptor, ionotropic, AMPA1 (alpha 1)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GRIA1 mRNA

NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070

G

glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

increases expression

beta-Naphthoflavone results in increased expression of GRINA mRNA

NCBI chr15:76,130,917...76,134,109
Ensembl chr15:76,130,964...76,134,104

G

glutamate receptor, metabotropic 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of GRM7 mRNA

NCBI chr 6:110,622,304...111,544,191
Ensembl chr 6:110,622,542...111,544,191

G

gasdermin D

increases expression

beta-Naphthoflavone results in increased expression of GSDMD mRNA

NCBI chr15:75,733,990...75,739,257
Ensembl chr15:75,734,176...75,739,257

G

glutathione reductase

increases expression

beta-Naphthoflavone results in increased expression of GSR mRNA

NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191

G

glutathione S-transferase, alpha 1 (Ya)

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GSTA5 mRNA; beta-Naphthoflavone results in increased expression of GSTA5 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTA5 mRNA]
Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA1 mRNA]
beta-Naphthoflavone results in increased expression of GSTA1 protein

PMID:2049074 PMID:9794803 PMID:15627257 PMID:18164116 PMID:19695238 More...

NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966

G

glutathione S-transferase, alpha 2 (Yc2)

increases expression
multiple interactions
increases activity

beta-Naphthoflavone results in increased expression of GSTA2 mRNA
beta-Naphthoflavone results in increased expression of GSTA2 mRNA; beta-Naphthoflavone results in increased expression of GSTA2 protein
Copper inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]; Copper promotes the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Lead inhibits the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]; Mercury inhibits the reaction [beta-Naphthoflavone results in increased activity of GSTA2 protein]; Mercury promotes the reaction [beta-Naphthoflavone results in increased expression of GSTA2 mRNA]

PMID:2049074 PMID:12883083 PMID:15297030 PMID:19695238

NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070

G

glutathione S-transferase, alpha 4

increases expression

beta-Naphthoflavone results in increased expression of GSTA4 protein

NCBI chr 9:78,099,248...78,116,631
Ensembl chr 9:78,090,056...78,116,631

G

glutathione S-transferase, mu 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of GSTM1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GSTM1 mRNA]

PMID:18164116 PMID:18723825 PMID:20045035 PMID:22687991

NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289

G

glutathione S-transferase, mu 2

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM2 mRNA
beta-Naphthoflavone results in increased expression of GSTM2 mRNA

PMID:19695238 PMID:19737545

NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769

G

glutathione S-transferase, mu 4

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM4 mRNA
beta-Naphthoflavone results in increased expression of GSTM4 mRNA

PMID:19695238 PMID:19737545

NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210

G

glutathione S-transferase, mu 5

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of GSTM3 mRNA
beta-Naphthoflavone results in increased expression of GSTM3 protein

PMID:9794803 PMID:19737545

NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002

G

glutathione S-transferase, pi 1

increases expression

beta-Naphthoflavone results in increased expression of GSTP1 mRNA; beta-Naphthoflavone results in increased expression of GSTP1 protein

PMID:9794803 PMID:19118567 PMID:19695238 PMID:23063670

NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985

G

glutathione S-transferase, pi 2

increases expression

beta-Naphthoflavone results in increased expression of GSTP2 mRNA

NCBI chr19:4,090,288...4,092,221
Ensembl chr19:4,090,285...4,096,023

G

glutathione S-transferase, theta 2

increases expression

beta-Naphthoflavone results in increased expression of GSTT2 mRNA

NCBI chr10:75,667,676...75,673,253
Ensembl chr10:75,666,948...75,673,258

G

guanylate cyclase 2c

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of GUCY2C mRNA

NCBI chr 6:136,674,282...136,758,740
Ensembl chr 6:136,674,282...136,758,763

G

glycophorin C

decreases expression

beta-Naphthoflavone results in decreased expression of GYPC mRNA

NCBI chr18:32,661,373...32,693,087
Ensembl chr18:32,661,375...32,693,087

G

H1.2 linker histone, cluster member

increases expression

beta-Naphthoflavone results in increased expression of H1-2 mRNA

NCBI chr13:23,922,790...23,923,514
Ensembl chr13:23,922,791...23,924,350

G

hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)

increases expression

beta-Naphthoflavone results in increased expression of H6PD mRNA

NCBI chr 4:150,063,931...150,093,480
Ensembl chr 4:150,063,932...150,093,480

G

hydroxyacyl glutathione hydrolase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HAGH mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HAGH mRNA]

NCBI chr17:25,056,863...25,083,424
Ensembl chr17:25,059,117...25,083,424

G

histidine ammonia lyase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HAL mRNA
beta-Naphthoflavone results in decreased expression of HAL mRNA

PMID:18164116 PMID:23994337

NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166

G

hepcidin antimicrobial peptide

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HAMP mRNA
beta-Naphthoflavone results in decreased expression of HAMP mRNA

PMID:18164116 PMID:32858204

NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457

G

HAUS augmin-like complex, subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HAUS1 mRNA

NCBI chr18:77,844,977...77,861,602
Ensembl chr18:77,845,267...77,861,586

G

hemoglobin, beta adult major chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HBB mRNA

G

hyperpolarization-activated, cyclic nucleotide-gated K+ 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HCN4 mRNA

NCBI chr 9:58,730,232...58,770,458
Ensembl chr 9:58,730,695...58,770,458

G

histone deacetylase 1

increases expression

beta-Naphthoflavone results in increased expression of HDAC1 protein

NCBI chr 4:129,409,897...129,436,516
Ensembl chr 4:129,409,897...129,436,506

G

histidine decarboxylase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HDC mRNA

NCBI chr 2:126,435,579...126,465,942
Ensembl chr 2:126,435,587...126,461,219

G

hes family bHLH transcription factor 2

decreases expression

beta-Naphthoflavone results in decreased expression of HES2 mRNA

NCBI chr 4:152,243,324...152,246,926
Ensembl chr 4:152,243,324...152,246,926

G

human immunodeficiency virus type I enhancer binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HIVEP2 mRNA

NCBI chr10:13,841,819...14,027,122
Ensembl chr10:13,841,819...14,027,118

G

3-hydroxy-3-methylglutaryl-Coenzyme A reductase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HMGCR mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCR mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444

G

3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HMGCS1 mRNA]

NCBI chr13:120,151,887...120,169,796
Ensembl chr13:120,151,915...120,169,796

G

heme oxygenase 1

multiple interactions
increases expression

[beta-Naphthoflavone co-treated with Copper] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Lead] results in increased expression of HMOX1 mRNA; [beta-Naphthoflavone co-treated with Mercury] results in increased expression of HMOX1 mRNA
beta-Naphthoflavone results in increased expression of HMOX1 protein
beta-Naphthoflavone results in increased expression of HMOX1 mRNA
isoquercitrin inhibits the reaction [beta-Naphthoflavone results in increased expression of HMOX1 protein]

PMID:15297030 PMID:15337587 PMID:19737606 PMID:21295105 PMID:22258563 More...

NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217

G

HOP homeobox

decreases expression

beta-Naphthoflavone results in decreased expression of HOPX mRNA

NCBI chr 5:77,234,831...77,262,970
Ensembl chr 5:77,234,835...77,262,968

G

homeobox A1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HOXA1 mRNA

NCBI chr 6:52,132,573...52,135,299
Ensembl chr 6:52,132,570...52,135,297

G

haptoglobin

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HP mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of HP mRNA

PMID:19737545 PMID:19737606

NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804

G

hydroxyprostaglandin dehydrogenase 15 (NAD)

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of HPGD mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HPGD mRNA
beta-Naphthoflavone results in decreased expression of HPGD mRNA

PMID:18164116 PMID:19737545 PMID:32858204

NCBI chr 8:56,747,587...56,774,081
Ensembl chr 8:56,747,620...56,774,078

G

hemopexin

decreases expression

beta-Naphthoflavone results in decreased expression of HPX mRNA

NCBI chr 7:105,240,818...105,249,323
Ensembl chr 7:105,240,820...105,249,344

G

hydroxysteroid 11-beta dehydrogenase 2

decreases expression

beta-Naphthoflavone results in decreased expression of HSD11B2 mRNA

NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620

G

hydroxysteroid (17-beta) dehydrogenase 1

decreases expression

beta-Naphthoflavone results in decreased expression of HSD17B1 mRNA

NCBI chr11:100,968,792...100,972,014
Ensembl chr11:100,969,237...100,971,353

G

hydroxysteroid (17-beta) dehydrogenase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSD17B2 mRNA

NCBI chr 8:118,427,752...118,485,767
Ensembl chr 8:118,428,643...118,485,766

G

hydroxysteroid (17-beta) dehydrogenase 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of HSD17B6 mRNA

NCBI chr10:127,826,800...127,843,517
Ensembl chr10:127,826,805...127,843,480

G

hydroxysteroid (17-beta) dehydrogenase 7

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of HSD17B7 mRNA]

NCBI chr 1:169,777,109...169,796,757
Ensembl chr 1:169,777,104...169,796,810

G

heat shock protein 90 alpha (cytosolic), class B member 1

increases expression

beta-Naphthoflavone results in increased expression of HSP90AB1 mRNA

NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197

G

heat shock protein 90, beta (Grp94), member 1

decreases expression

beta-Naphthoflavone results in decreased expression of HSP90B1 mRNA

NCBI chr10:86,526,705...86,541,308
Ensembl chr10:86,526,073...86,541,373

G

heat shock protein 12A

decreases expression

beta-Naphthoflavone results in decreased expression of HSPA12A mRNA

NCBI chr19:58,784,182...58,932,104
Ensembl chr19:58,784,182...58,932,086

G

heat shock protein 1A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPA1A mRNA

NCBI chr17:35,188,335...35,191,132
Ensembl chr17:35,188,166...35,191,132

G

heat shock protein 1B

increases expression

beta-Naphthoflavone results in increased expression of HSPA1B mRNA

NCBI chr17:35,175,405...35,178,214
Ensembl chr17:35,175,412...35,178,214

G

heat shock protein 4 like

increases expression

beta-Naphthoflavone results in increased expression of HSPA4L mRNA

NCBI chr 3:40,698,664...40,750,538
Ensembl chr 3:40,699,814...40,750,538

G

heat shock protein 5

increases expression

beta-Naphthoflavone results in increased expression of HSPA5 mRNA

NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559

G

heat shock protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of HSPB2 mRNA

NCBI chr 9:50,662,372...50,663,654
Ensembl chr 9:50,662,378...50,663,654

G

heat shock protein 8

increases expression

beta-Naphthoflavone results in increased expression of HSPB8 mRNA

NCBI chr 5:116,546,550...116,560,923
Ensembl chr 5:116,546,550...116,560,923

G

HtrA serine peptidase 1

decreases expression

beta-Naphthoflavone results in decreased expression of HTRA1 mRNA

NCBI chr 7:130,537,933...130,587,388
Ensembl chr 7:130,537,841...130,587,390

G

HtrA serine peptidase 4

decreases expression

beta-Naphthoflavone results in decreased expression of HTRA4 mRNA

NCBI chr 8:25,514,944...25,529,160
Ensembl chr 8:25,514,945...25,528,978

G

islet cell autoantigen 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ICA1 mRNA

NCBI chr 6:8,630,527...8,778,531
Ensembl chr 6:8,630,527...8,778,488

G

inhibitor of DNA binding 1, HLH protein

decreases expression

beta-Naphthoflavone results in decreased expression of ID1 mRNA

NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330

G

inhibitor of DNA binding 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ID4 mRNA

NCBI chr13:48,414,592...48,419,504
Ensembl chr13:48,414,704...48,419,502

G

isopentenyl-diphosphate delta isomerase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IDI1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IDI1 mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487

G

immediate early response 3

increases expression

beta-Naphthoflavone results in increased expression of IER3 mRNA

NCBI chr17:36,132,605...36,133,803
Ensembl chr17:36,132,576...36,133,815

G

immediate early response 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IER5 mRNA

NCBI chr 1:154,972,113...154,975,382
Ensembl chr 1:154,972,107...154,975,382

G

interferon-induced protein with tetratricopeptide repeats 3

decreases expression

beta-Naphthoflavone results in decreased expression of IFIT3 mRNA

NCBI chr19:34,560,519...34,566,382
Ensembl chr19:34,560,931...34,566,131

G

interferon induced transmembrane protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM1 mRNA

NCBI chr 7:140,547,342...140,549,740
Ensembl chr 7:140,547,134...140,549,738

G

interferon induced transmembrane protein 2

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM2 mRNA

NCBI chr 7:140,534,750...140,539,602
Ensembl chr 7:140,534,750...140,535,900

G

interferon induced transmembrane protein 3

decreases expression

beta-Naphthoflavone results in decreased expression of IFITM3 mRNA

NCBI chr 7:140,589,503...140,590,657
Ensembl chr 7:140,589,499...140,590,683

G

immunoglobulin superfamily, DCC subclass, member 4

decreases expression

beta-Naphthoflavone results in decreased expression of IGDCC4 mRNA

PMID:19737606 PMID:32858204

NCBI chr 9:65,008,246...65,045,225
Ensembl chr 9:65,008,768...65,045,222

G

insulin-like growth factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGF1 mRNA

NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904

G

insulin-like growth factor binding protein 1

increases expression

beta-Naphthoflavone results in increased expression of IGFBP1 mRNA

NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546

G

insulin-like growth factor binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IGFBP2 mRNA

NCBI chr 1:72,863,650...72,891,633
Ensembl chr 1:72,863,662...72,891,633

G

insulin-like growth factor binding protein 3

increases expression

beta-Naphthoflavone results in increased expression of IGFBP3 mRNA

NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923

G

insulin-like growth factor binding protein 7

decreases expression

beta-Naphthoflavone results in decreased expression of IGFBP7 mRNA

NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888

G

immunoglobulin superfamily, member 3

decreases expression

beta-Naphthoflavone results in decreased expression of IGSF3 mRNA

NCBI chr 3:101,284,306...101,370,375
Ensembl chr 3:101,284,399...101,370,375

G

immunoglobulin superfamily, member 5

decreases expression

beta-Naphthoflavone results in decreased expression of IGSF5 mRNA

NCBI chr16:96,162,676...96,266,772
Ensembl chr16:96,162,868...96,223,321

G

Indian hedgehog

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IHH mRNA

NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831

G

inhibitor of kappaB kinase epsilon

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of IKBKE mRNA

NCBI chr 1:131,182,337...131,207,339
Ensembl chr 1:131,182,080...131,207,344

G

interleukin 11

increases expression

beta-Naphthoflavone results in increased expression of IL11 mRNA

NCBI chr 7:4,775,372...4,785,877
Ensembl chr 7:4,775,372...4,785,858

G

interleukin 12a

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL12A mRNA

NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880

G

interleukin 13

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL13 protein]

NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529

G

interleukin 17A

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL17A protein]

NCBI chr 1:20,801,129...20,804,720
Ensembl chr 1:20,801,129...20,804,720

G

interleukin 1 alpha

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of IL1A mRNA
[isoquercitrin co-treated with Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IL1A mRNA

PMID:8156173 PMID:21295105 PMID:32151702

NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892

G

interleukin 1 beta

decreases expression
multiple interactions
increases expression

beta-Naphthoflavone results in decreased expression of IL1B mRNA
IL1B protein promotes the reaction [beta-Naphthoflavone results in increased expression of CXCL5 mRNA]
beta-Naphthoflavone results in increased expression of IL1B mRNA

PMID:8156173 PMID:28973351 PMID:32151702 PMID:32858204

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

G

interleukin 1 receptor, type I

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL1R1 mRNA

NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417

G

interleukin 1 receptor, type II

increases expression

beta-Naphthoflavone results in increased expression of IL1R2 mRNA

NCBI chr 1:40,123,872...40,164,390
Ensembl chr 1:40,113,239...40,164,391

G

interleukin 1 receptor antagonist

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of IL1RN mRNA
beta-Naphthoflavone results in decreased expression of IL1RN mRNA

PMID:32151702 PMID:32858204

NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506

G

interleukin 20

increases expression

beta-Naphthoflavone results in increased expression of IL20 mRNA

NCBI chr 1:130,834,722...130,839,033
Ensembl chr 1:130,834,722...130,839,188

G

interleukin 22B

increases expression

beta-Naphthoflavone results in increased expression of IL22 mRNA

NCBI chr10:118,125,534...118,130,943
Ensembl chr10:118,125,534...118,130,943

G

interleukin 23, alpha subunit p19

increases expression

beta-Naphthoflavone results in increased expression of IL23A mRNA

NCBI chr10:128,132,009...128,133,953
Ensembl chr10:128,132,008...128,134,621

G

interleukin 24

increases expression

beta-Naphthoflavone results in increased expression of IL24 mRNA

NCBI chr 1:130,809,801...130,815,153
Ensembl chr 1:130,809,811...130,815,191

G

interleukin 2 receptor, beta chain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL2RB mRNA

NCBI chr15:78,363,456...78,396,569
Ensembl chr15:78,363,456...78,379,471

G

interleukin 36G

increases expression

beta-Naphthoflavone results in increased expression of IL36G mRNA

NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580

G

interleukin 5

multiple interactions

beta-Naphthoflavone promotes the reaction [Plant Extracts results in increased expression of IL5 protein]

NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933

G

interleukin 6

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IL6 mRNA
beta-Naphthoflavone results in increased expression of IL6 mRNA

PMID:8156173 PMID:21295105 PMID:32151702

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

G

ilvB (bacterial acetolactate synthase)-like

decreases expression

beta-Naphthoflavone results in decreased expression of ILVBL mRNA

NCBI chr10:78,410,178...78,420,336
Ensembl chr10:78,410,180...78,420,336

G

inhibin beta-B

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of INHBB mRNA
beta-Naphthoflavone results in decreased expression of INHBB mRNA

PMID:18164116 PMID:19737606

NCBI chr 1:119,343,193...119,349,978
Ensembl chr 1:119,343,195...119,349,978

G

inhibin beta-E

increases expression

beta-Naphthoflavone results in increased expression of INHBE mRNA

NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280

G

insulin induced gene 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of INSIG2 mRNA

NCBI chr 1:121,232,082...121,260,391
Ensembl chr 1:121,232,082...121,260,318

G

interleukin-1 receptor-associated kinase 2

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of IRAK2 mRNA
beta-Naphthoflavone results in decreased expression of IRAK2 mRNA

PMID:32151702 PMID:32858204

NCBI chr 6:113,615,428...113,671,987
Ensembl chr 6:113,615,428...113,671,987

G

interferon regulatory factor 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IRF1 mRNA
beta-Naphthoflavone results in decreased expression of IRF1 mRNA

PMID:18164116 PMID:32858204

NCBI chr11:53,660,841...53,669,200
Ensembl chr11:53,660,841...53,669,200

G

interferon regulatory factor 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of IRF7 mRNA

NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394

G

immunity-related GTPase family M member 1

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of IRGM mRNA]

NCBI chr11:48,756,072...48,762,247
Ensembl chr11:48,752,795...48,762,510

G

insulin receptor substrate 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of IRS2 mRNA

NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458

G

ISG15 ubiquitin-like modifier

decreases expression

beta-Naphthoflavone results in decreased expression of ISG15 mRNA

NCBI chr 4:156,283,881...156,285,275
Ensembl chr 4:156,283,912...156,285,253

G

interferon-stimulated protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ISG20 mRNA

NCBI chr 7:78,561,136...78,570,144
Ensembl chr 7:78,563,172...78,570,144

G

isthmin 2

decreases expression

beta-Naphthoflavone results in decreased expression of ISM2 mRNA

NCBI chr12:87,325,412...87,346,624
Ensembl chr12:87,325,412...87,346,479

G

integrin alpha 5 (fibronectin receptor alpha)

decreases expression

beta-Naphthoflavone results in decreased expression of ITGA5 mRNA

NCBI chr15:103,252,713...103,275,218
Ensembl chr15:103,252,713...103,275,190

G

integrin alpha 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITGA8 mRNA

NCBI chr 2:12,111,443...12,306,755
Ensembl chr 2:12,111,443...12,306,733

G

integrin beta 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITGB6 mRNA

NCBI chr 2:60,428,636...60,553,005
Ensembl chr 2:60,428,636...60,552,987

G

intelectin 1 (galactofuranose binding)

decreases expression

beta-Naphthoflavone results in decreased expression of ITLN1 mRNA

NCBI chr 1:171,345,691...171,362,893
Ensembl chr 1:171,345,690...171,362,862

G

inositol 1,4,5-trisphosphate 3-kinase B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ITPKB mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ITPKB mRNA

NCBI chr 1:180,156,655...180,252,367
Ensembl chr 1:180,158,050...180,252,367

G

involucrin

increases expression

beta-Naphthoflavone results in increased expression of IVL mRNA

NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042

G

junction adhesion molecule 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of JAM2 mRNA

NCBI chr16:84,571,011...84,623,268
Ensembl chr16:84,571,011...84,622,816

G

Josephin domain containing 1

increases expression

beta-Naphthoflavone results in increased expression of JOSD1 mRNA

NCBI chr15:79,558,451...79,572,073
Ensembl chr15:79,558,452...79,572,120

G

jun proto-oncogene

multiple interactions

beta-Naphthoflavone promotes the reaction [JUN protein binds to NQO1 promoter]

NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459

G

jun B proto-oncogene

increases expression

beta-Naphthoflavone results in increased expression of JUNB mRNA

NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347

G

jun D proto-oncogene

increases expression

beta-Naphthoflavone results in increased expression of JUND mRNA

NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265

G

kalirin, RhoGEF kinase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KALRN mRNA

NCBI chr16:33,789,443...34,393,647
Ensembl chr16:33,789,443...34,393,902

G

KN motif and ankyrin repeat domains 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KANK1 mRNA

NCBI chr19:25,214,146...25,411,861
Ensembl chr19:25,214,339...25,411,860

G

potassium voltage-gated channel, shaker-related subfamily, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KCNA2 mRNA

NCBI chr 3:106,998,203...107,022,321
Ensembl chr 3:107,008,462...107,022,321

G

potassium channel, subfamily T, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KCNT2 mRNA

NCBI chr 1:140,173,373...140,541,783
Ensembl chr 1:140,173,896...140,539,805

G

kinesin family member 12

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF12 mRNA

NCBI chr 4:63,076,185...63,090,382
Ensembl chr 4:63,083,867...63,090,368

G

kinesin family member 22

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF22 mRNA

NCBI chr 7:126,626,901...126,641,639
Ensembl chr 7:126,626,901...126,641,643

G

kinesin family member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KIF4 mRNA

NCBI chr X:99,669,693...99,770,878
Ensembl chr X:99,669,343...99,770,820

G

KiSS-1 metastasis-suppressor

decreases expression

beta-Naphthoflavone results in decreased expression of KISS1 mRNA

NCBI chr 1:133,249,625...133,257,460
Ensembl chr 1:133,237,565...133,257,460
Ensembl chr 1:133,237,565...133,257,460

G

Kruppel-like transcription factor 2 (lung)

increases expression

beta-Naphthoflavone results in increased expression of KLF2 mRNA

NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500

G

Kruppel-like transcription factor 6

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of KLF6 mRNA
[CYP2E1 protein co-treated with beta-Naphthoflavone] results in increased expression of KLF6 protein

PMID:19737606 PMID:22486562

NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393

G

kelch domain containing 8B

decreases expression

beta-Naphthoflavone results in decreased expression of KLHDC8B mRNA

NCBI chr 9:108,324,834...108,338,780
Ensembl chr 9:108,324,835...108,338,780

G

kallikrein related-peptidase 14

increases expression

beta-Naphthoflavone results in increased expression of KLK14 mRNA

NCBI chr 7:43,330,305...43,344,960
Ensembl chr 7:43,339,842...43,344,960

G

killer cell lectin-like receptor subfamily G, member 1

increases expression

beta-Naphthoflavone results in increased expression of KLRG1 mRNA

NCBI chr 6:122,247,555...122,259,792
Ensembl chr 6:122,247,555...122,259,841

G

kinetochore-localized astrin/SPAG5 binding

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KNSTRN mRNA

NCBI chr 2:118,644,470...118,667,691
Ensembl chr 2:118,644,484...118,684,438

G

karyopherin subunit alpha 6

increases expression

beta-Naphthoflavone results in increased expression of KPNA6 mRNA

NCBI chr 4:129,537,772...129,566,560
Ensembl chr 4:129,537,773...129,566,560

G

keratin 1

affects expression

beta-Naphthoflavone affects the expression of KRT1 mRNA

NCBI chr15:101,753,861...101,759,221
Ensembl chr15:101,753,861...101,759,229

G

keratin 10

decreases expression

beta-Naphthoflavone results in decreased expression of KRT10 mRNA

NCBI chr11:99,276,080...99,288,631
Ensembl chr11:99,276,080...99,280,190

G

keratin 13

increases expression

beta-Naphthoflavone results in increased expression of KRT13 mRNA

NCBI chr11:100,008,153...100,012,392
Ensembl chr11:100,008,153...100,012,392

G

keratin 14

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KRT14 mRNA

NCBI chr11:100,093,988...100,098,336
Ensembl chr11:100,093,988...100,098,374

G

keratin 19

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KRT19 mRNA
beta-Naphthoflavone results in increased expression of KRT19 mRNA

PMID:18164116 PMID:32151702

NCBI chr11:100,031,636...100,036,752
Ensembl chr11:100,031,636...100,039,491

G

keratin 20

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KRT20 mRNA

NCBI chr11:99,319,211...99,328,979
Ensembl chr11:99,319,229...99,328,976

G

keratin 23

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KRT23 mRNA
beta-Naphthoflavone results in decreased expression of KRT23 mRNA

PMID:18164116 PMID:32858204

NCBI chr11:99,368,799...99,383,946
Ensembl chr11:99,368,800...99,383,963

G

keratin 31

increases expression

beta-Naphthoflavone results in increased expression of KRT31 mRNA

NCBI chr11:99,937,472...99,941,377
Ensembl chr11:99,937,472...99,941,377

G

keratin 34

increases expression

beta-Naphthoflavone results in increased expression of KRT34 mRNA

NCBI chr11:99,928,173...99,932,380
Ensembl chr11:99,928,173...99,932,380

G

keratin 5

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of KRT5 mRNA

NCBI chr15:101,615,504...101,621,340
Ensembl chr15:101,615,505...101,621,333

G

keratin 6B

increases expression

beta-Naphthoflavone results in increased expression of KRT6B mRNA

NCBI chr15:101,584,458...101,588,728
Ensembl chr15:101,584,458...101,588,722

G

keratin 78

increases expression

beta-Naphthoflavone results in increased expression of KRT78 mRNA

NCBI chr15:101,854,436...101,905,059
Ensembl chr15:101,854,436...101,862,722

G

keratin associated protein 3-3

increases expression

beta-Naphthoflavone results in increased expression of KRTAP3-3 mRNA

NCBI chr11:99,440,958...99,441,689
Ensembl chr11:99,440,956...99,441,691

G

keratinocyte differentiation associated protein

increases expression

beta-Naphthoflavone results in increased expression of KRTDAP mRNA

NCBI chr 7:30,487,330...30,490,514
Ensembl chr 7:30,487,321...30,490,522

G

kynureninase

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of KYNU mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of KYNU mRNA

PMID:18164116 PMID:19737606

NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734

G

lactalbumin, alpha

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of LALBA mRNA
AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of LALBA mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of LALBA mRNA]

NCBI chr15:98,378,281...98,380,827
Ensembl chr15:98,378,281...98,380,602

G

laminin, alpha 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LAMA5 mRNA

NCBI chr 2:179,818,166...179,867,652
Ensembl chr 2:179,818,166...179,867,652

G

laminin, beta 3

increases expression

beta-Naphthoflavone results in increased expression of LAMB3 mRNA

NCBI chr 1:192,976,661...193,026,186
Ensembl chr 1:192,890,007...193,026,186

G

lipopolysaccharide binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LBP mRNA

NCBI chr 2:158,148,413...158,174,772
Ensembl chr 2:158,148,413...158,174,772

G

leptin

decreases expression

beta-Naphthoflavone results in decreased expression of LEP mRNA

NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876

G

leptin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LEPR mRNA

NCBI chr 4:101,574,393...101,676,375
Ensembl chr 4:101,574,601...101,672,549

G

lectin, galactose binding, soluble 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS1 mRNA

NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665

G

lectin, galactose-binding, soluble 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS2 mRNA

NCBI chr15:78,735,060...78,739,729
Ensembl chr15:78,735,060...78,739,729

G

lectin, galactose binding, soluble 3

increases expression

beta-Naphthoflavone results in increased expression of LGALS3 mRNA

NCBI chr14:47,611,317...47,623,624
Ensembl chr14:47,605,208...47,623,617

G

lectin, galactoside-binding, soluble, 3 binding protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LGALS3BP mRNA

NCBI chr11:118,283,573...118,292,787
Ensembl chr11:118,283,577...118,292,918

G

legumain

decreases expression

beta-Naphthoflavone results in decreased expression of LGMN mRNA

NCBI chr12:102,360,341...102,405,987
Ensembl chr12:102,360,343...102,406,072

G

luteinizing hormone/choriogonadotropin receptor

multiple interactions

beta-Naphthoflavone inhibits the reaction [FSHB protein results in increased expression of LHCGR mRNA]

NCBI chr17:89,023,812...89,099,487
Ensembl chr17:89,023,909...89,099,418

G

leukemia inhibitory factor

increases expression

beta-Naphthoflavone results in increased expression of LIF mRNA

NCBI chr11:4,207,587...4,222,514
Ensembl chr11:4,207,557...4,222,514

G

LIM and calponin homology domains 1

decreases expression

beta-Naphthoflavone results in decreased expression of LIMCH1 mRNA

NCBI chr 5:66,903,232...67,214,502
Ensembl chr 5:66,903,170...67,214,501

G

LIM and cysteine-rich domains 1

increases expression

beta-Naphthoflavone results in increased expression of LMCD1 mRNA

NCBI chr 6:112,250,747...112,307,384
Ensembl chr 6:112,250,719...112,307,386

G

LIM domain only 7

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LMO7 mRNA

NCBI chr14:101,967,353...102,172,144
Ensembl chr14:101,967,386...102,172,146

G

leucyl/cystinyl aminopeptidase

decreases expression

beta-Naphthoflavone results in decreased expression of LNPEP mRNA

NCBI chr17:17,747,985...17,846,303
Ensembl chr17:17,741,672...17,845,312

G

loricrin cornified envelope precursor protein

decreases expression

beta-Naphthoflavone results in decreased expression of LORICRIN mRNA

NCBI chr 3:91,987,578...91,990,447
Ensembl chr 3:91,987,578...91,990,449

G

lysyl oxidase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOX mRNA

NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939

G

lysyl oxidase-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LOXL1 mRNA

NCBI chr 9:58,195,006...58,220,495
Ensembl chr 9:58,195,021...58,220,469

G

lysophosphatidic acid receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPAR1 mRNA

NCBI chr 4:58,435,252...58,554,601
Ensembl chr 4:58,435,255...58,553,898

G

lysophosphatidic acid receptor 6

increases expression

beta-Naphthoflavone results in increased expression of LPAR6 mRNA

NCBI chr14:73,475,331...73,477,798
Ensembl chr14:73,475,335...73,480,734

G

lipin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPIN1 mRNA

NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967

G

lipin 2

increases expression

beta-Naphthoflavone results in increased expression of LPIN2 mRNA

NCBI chr17:71,490,527...71,556,813
Ensembl chr17:71,489,555...71,556,812

G

lipoprotein lipase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LPL mRNA
beta-Naphthoflavone results in decreased expression of LPL mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100

G

lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LRAT mRNA

NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280

G

low density lipoprotein receptor-related protein 2

increases expression

beta-Naphthoflavone results in increased expression of LRP2 mRNA

NCBI chr 2:69,254,679...69,416,373
Ensembl chr 2:69,254,684...69,416,409

G

leucine rich repeat containing 25

increases expression

beta-Naphthoflavone results in increased expression of LRRC25 mRNA

NCBI chr 8:71,068,810...71,073,501
Ensembl chr 8:71,068,805...71,074,133

G

leucine rich repeat containing 32

decreases expression

beta-Naphthoflavone results in decreased expression of LRRC32 mRNA

NCBI chr 7:98,138,515...98,151,038
Ensembl chr 7:98,138,490...98,151,388

G

leucine rich repeat protein 3, neuronal

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LRRN3 mRNA

NCBI chr12:41,501,667...41,536,056
Ensembl chr12:41,501,667...41,536,430

G

lanosterol synthase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of LSS mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of LSS mRNA]

NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972

G

lymphotoxin B

increases expression

beta-Naphthoflavone results in increased expression of LTB mRNA

NCBI chr17:35,413,483...35,415,281
Ensembl chr17:35,413,415...35,415,296

G

latent transforming growth factor beta binding protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP1 mRNA

NCBI chr17:75,312,475...75,699,507
Ensembl chr17:75,312,563...75,699,507

G

latent transforming growth factor beta binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP2 mRNA

NCBI chr12:84,829,986...84,923,581
Ensembl chr12:84,829,986...84,923,306

G

latent transforming growth factor beta binding protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LTBP3 mRNA

NCBI chr19:5,790,928...5,808,564
Ensembl chr19:5,790,932...5,808,560

G

leukotriene C4 synthase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of LTC4S mRNA

NCBI chr11:50,127,288...50,129,378
Ensembl chr11:50,127,288...50,129,443

G

latexin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of LXN mRNA

NCBI chr 3:67,365,332...67,371,240
Ensembl chr 3:67,365,331...67,371,259

G

lysozyme-like 1

decreases expression

beta-Naphthoflavone results in decreased expression of LYZL1 mRNA

NCBI chr18:4,165,862...4,182,232
Ensembl chr18:4,165,832...4,182,232

G

MAF bZIP transcription factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAF mRNA

NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533

G

MAF bZIP transcription factor B

increases expression

beta-Naphthoflavone results in increased expression of MAFB mRNA

NCBI chr 2:160,205,597...160,208,985
Ensembl chr 2:160,205,623...160,208,985

G

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)

increases expression

beta-Naphthoflavone results in increased expression of MAFF mRNA

NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276

G

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

increases expression

beta-Naphthoflavone results in increased expression of MAFG mRNA

PMID:32151702 PMID:32858204

NCBI chr11:120,515,943...120,525,771
Ensembl chr11:120,515,943...120,524,426

G

v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAFK mRNA

NCBI chr 5:139,777,291...139,788,409
Ensembl chr 5:139,777,268...139,788,408

G

MAGE family member D1

decreases expression

beta-Naphthoflavone results in decreased expression of MAGED1 mRNA

NCBI chr X:93,579,080...93,585,631
Ensembl chr X:93,579,080...93,585,749

G

MAGE family member D2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAGED2 mRNA

NCBI chr X:149,589,417...149,597,358
Ensembl chr X:149,589,366...149,597,341

G

MAGE family member H1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAGEH1 mRNA

NCBI chr X:151,819,162...151,820,559
Ensembl chr X:151,819,162...151,820,571

G

mannosidase, alpha, class 1C, member 1

decreases expression

beta-Naphthoflavone results in decreased expression of MAN1C1 mRNA

NCBI chr 4:134,289,001...134,432,987
Ensembl chr 4:134,289,001...134,431,601

G

monoamine oxidase A

decreases expression

beta-Naphthoflavone results in decreased expression of MAOA mRNA

NCBI chr X:16,485,937...16,554,051
Ensembl chr X:16,485,937...16,554,057

G

mitogen-activated protein kinase kinase 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MAP2K5 mRNA

NCBI chr 9:63,071,050...63,288,964
Ensembl chr 9:63,071,050...63,285,184

G

mitogen-activated protein kinase 1

increases phosphorylation
multiple interactions

beta-Naphthoflavone results in increased phosphorylation of MAPK1 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MAPK1 mRNA

PMID:18164116 PMID:23228475

NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317

G

mitogen-activated protein kinase 3

increases phosphorylation

beta-Naphthoflavone results in increased phosphorylation of MAPK3 protein

NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991

G

MAP kinase-activated protein kinase 5

increases expression

beta-Naphthoflavone results in increased expression of MAPKAPK5 mRNA

NCBI chr 5:121,663,114...121,683,955
Ensembl chr 5:121,663,101...121,683,968

G

microtubule-associated protein tau

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MAPT mRNA

NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916

G

methionine adenosyltransferase 2 non-catalytic beta subunit methionine

increases expression

beta-Naphthoflavone results in increased expression of MAT2B mRNA

NCBI chr11:40,570,141...40,586,030
Ensembl chr11:40,570,141...40,586,030

G

myelin basic protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MBP mRNA

NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762

G

mast cell expressed membrane protein 1

increases expression

beta-Naphthoflavone results in increased expression of MCEMP1 mRNA

NCBI chr 8:3,715,754...3,718,916
Ensembl chr 8:3,715,754...3,719,259

G

minichromosome maintenance complex component 3 associated protein

increases expression

beta-Naphthoflavone results in increased expression of MCM3AP mRNA

NCBI chr10:76,304,736...76,351,693
Ensembl chr10:76,304,761...76,351,691

G

malate dehydrogenase 1, NAD (soluble)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MDH1 mRNA

NCBI chr11:21,506,692...21,521,934
Ensembl chr11:21,506,692...21,522,367

G

transformed mouse 3T3 cell double minute 2

increases phosphorylation

beta-Naphthoflavone results in increased phosphorylation of MDM2 protein

NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663

G

transformed mouse 3T3 cell double minute 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MDM4 mRNA

NCBI chr 1:132,913,843...132,958,325
Ensembl chr 1:132,887,222...132,958,299

G

malic enzyme 1, NADP(+)-dependent, cytosolic

increases expression

beta-Naphthoflavone results in increased expression of ME1 mRNA

NCBI chr 9:86,463,416...86,577,967
Ensembl chr 9:86,463,424...86,578,006

G

methyl CpG binding protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MECP2 mRNA

NCBI chr X:73,070,198...73,129,296
Ensembl chr X:73,070,198...73,129,296

G

multiple EGF-like-domains 8

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEGF8 mRNA

NCBI chr 7:25,016,589...25,065,342
Ensembl chr 7:25,016,589...25,065,342

G

mesenchyme homeobox 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MEOX2 mRNA

NCBI chr12:37,158,539...37,229,533
Ensembl chr12:37,158,539...37,229,533

G

mesoderm specific transcript

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MEST mRNA

NCBI chr 6:30,733,505...30,783,580
Ensembl chr 6:30,723,546...30,748,464

G

microfibrillar-associated protein 4

decreases expression

beta-Naphthoflavone results in decreased expression of MFAP4 mRNA

NCBI chr11:61,376,257...61,379,536
Ensembl chr11:61,376,257...61,379,726

G

MFSD2 lysolipid transporter A, lysophospholipid

decreases expression

beta-Naphthoflavone results in decreased expression of MFSD2A mRNA

NCBI chr 4:122,840,643...122,855,844
Ensembl chr 4:122,840,643...122,854,981

G

matrix Gla protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MGP mRNA

NCBI chr 6:136,849,433...136,852,821
Ensembl chr 6:136,849,433...136,852,821

G

microsomal glutathione S-transferase 1

increases expression

beta-Naphthoflavone results in increased expression of MGST1 mRNA

NCBI chr 6:138,117,525...138,133,753
Ensembl chr 6:138,117,314...138,133,753

G

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MID1IP1 mRNA

NCBI chr X:10,583,604...10,585,941
Ensembl chr X:10,581,252...10,585,929

G

meiosis regulator for oocyte development

increases expression

beta-Naphthoflavone results in increased expression of MIOS mRNA

NCBI chr 6:8,209,111...8,240,573
Ensembl chr 6:8,209,222...8,236,274

G

MAP kinase-interacting serine/threonine kinase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MKNK2 mRNA

NCBI chr10:80,501,152...80,512,264
Ensembl chr10:80,501,161...80,513,946

G

monocyte to macrophage differentiation-associated

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMD mRNA

NCBI chr11:90,078,513...90,169,399
Ensembl chr11:90,140,282...90,169,415

G

membrane metallo endopeptidase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MME mRNA

NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451

G

matrix metallopeptidase 10

increases expression

beta-Naphthoflavone results in increased expression of MMP10 mRNA

NCBI chr 9:7,502,343...7,510,243
Ensembl chr 9:7,502,353...7,510,241

G

matrix metallopeptidase 11

decreases expression

beta-Naphthoflavone results in decreased expression of MMP11 mRNA

NCBI chr10:75,759,056...75,768,336
Ensembl chr10:75,759,056...75,772,330

G

matrix metallopeptidase 12

increases expression

beta-Naphthoflavone results in increased expression of MMP12 mRNA

NCBI chr 9:7,344,397...7,360,461
Ensembl chr 9:7,344,381...7,369,499

G

matrix metallopeptidase 14 (membrane-inserted)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MMP14 mRNA

NCBI chr14:54,669,055...54,679,913
Ensembl chr14:54,669,069...54,682,821

G

matrix metallopeptidase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP2 mRNA

PMID:18164116 PMID:20045035

NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048

G

matrix metallopeptidase 23

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MMP23 mRNA
beta-Naphthoflavone results in decreased expression of MMP23 mRNA

PMID:18164116 PMID:23994337

NCBI chr 4:155,735,111...155,738,982
Ensembl chr 4:155,735,112...155,737,841

G

matrix metallopeptidase 3

increases expression

beta-Naphthoflavone results in increased expression of MMP3 mRNA

NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975

G

matrix metallopeptidase 9

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of MMP9 mRNA
beta-Naphthoflavone results in decreased expression of MMP9 mRNA

PMID:32151702 PMID:32858204

NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770

G

myelin protein zero-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MPZL1 mRNA

NCBI chr 1:165,419,745...165,462,144
Ensembl chr 1:165,419,809...165,462,107

G

mitochondrial ribosomal protein L37

increases expression

beta-Naphthoflavone results in increased expression of MRPL37 mRNA

NCBI chr 4:106,913,071...106,924,063
Ensembl chr 4:106,913,071...106,924,065

G

mitochondrial ribosomal protein S24

increases expression

beta-Naphthoflavone results in increased expression of MRPS24 mRNA

NCBI chr11:5,653,982...5,657,701
Ensembl chr11:5,653,983...5,665,680

G

methylsterol monoxygenase 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MSMO1 mRNA
beta-Naphthoflavone results in decreased expression of MSMO1 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MSMO1 mRNA]

PMID:18164116 PMID:22234961

NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826

G

methionine sulfoxide reductase A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MSRA mRNA

NCBI chr14:64,360,070...64,693,352
Ensembl chr14:64,360,074...64,693,352

G

metallothionein 1

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of MT1 mRNA
beta-Naphthoflavone results in increased expression of MT1X mRNA
beta-Naphthoflavone results in decreased expression of MT1X mRNA

PMID:14998373 PMID:32151702 PMID:32858204

NCBI chr 8:94,905,214...94,906,955
Ensembl chr 8:94,905,710...94,906,955

G

metallothionein 2

decreases expression

beta-Naphthoflavone results in decreased expression of MT2A mRNA

NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196

G

myotubularin related protein 10

decreases expression

beta-Naphthoflavone results in decreased expression of MTMR10 mRNA

NCBI chr 7:63,937,443...63,990,556
Ensembl chr 7:63,937,401...63,990,554

G

mitochondrial tumor suppressor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MTUS1 mRNA

NCBI chr 8:41,443,949...41,587,318
Ensembl chr 8:41,443,951...41,586,763

G

mucin 1, transmembrane

decreases expression

beta-Naphthoflavone results in decreased expression of MUC1 mRNA

NCBI chr 3:89,136,363...89,140,688
Ensembl chr 3:89,136,364...89,140,688

G

major urinary protein 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of MUP4 mRNA

NCBI chr 4:59,956,804...59,960,667
Ensembl chr 4:59,956,804...59,960,710

G

mevalonate (diphospho) decarboxylase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MVD mRNA
beta-Naphthoflavone results in decreased expression of MVD mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of MVD mRNA]

PMID:18164116 PMID:22234961 PMID:31225620

NCBI chr 8:123,160,335...123,170,161
Ensembl chr 8:123,160,340...123,170,161

G

mevalonate kinase

decreases expression

beta-Naphthoflavone results in decreased expression of MVK mRNA

NCBI chr 5:114,582,324...114,598,652
Ensembl chr 5:114,582,330...114,598,652

G

myosin binding protein H

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MYBPH mRNA

NCBI chr 1:134,121,159...134,128,975
Ensembl chr 1:134,121,186...134,128,970

G

myosin, heavy polypeptide 10, non-muscle

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of MYH10 mRNA

NCBI chr11:68,581,228...68,707,451
Ensembl chr11:68,582,385...68,707,458

G

myoferlin

increases expression

beta-Naphthoflavone results in increased expression of MYOF mRNA

NCBI chr19:37,887,484...38,032,025
Ensembl chr19:37,887,484...38,032,025

G

myozenin 2

increases expression

beta-Naphthoflavone results in increased expression of MYOZ2 mRNA

NCBI chr 3:122,799,855...122,828,649
Ensembl chr 3:122,799,855...122,828,664

G

N-acetylated alpha-linked acidic dipeptidase 2

decreases expression

beta-Naphthoflavone results in decreased expression of NAALAD2 mRNA

NCBI chr 9:18,233,247...18,308,834
Ensembl chr 9:18,233,247...18,314,291

G

N-acetyltransferase 8 (GCN5-related) family member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NAT8F1 mRNA

NCBI chr 6:85,887,136...85,893,210
Ensembl chr 6:85,887,136...85,892,669

G

N-acetyltransferase 8 (GCN5-related) family member 2

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NAT8F2 mRNA]

NCBI chr 6:85,842,404...85,846,119
Ensembl chr 6:85,842,404...85,846,140

G

neuron navigator 2

decreases expression

beta-Naphthoflavone results in decreased expression of NAV2 mRNA

NCBI chr 7:48,608,796...49,259,838
Ensembl chr 7:48,558,464...49,259,838

G

neutrophil cytosolic factor 1

increases expression

beta-Naphthoflavone results in increased expression of NCF1 mRNA

NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479

G

N-terminal EF-hand calcium binding protein 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of NECAB1 mRNA

NCBI chr 4:14,952,245...15,149,804
Ensembl chr 4:14,952,245...15,149,794

G

nectin cell adhesion molecule 3

decreases expression

beta-Naphthoflavone results in decreased expression of NECTIN3 mRNA

NCBI chr16:46,208,028...46,318,898
Ensembl chr16:46,208,069...46,318,888

G

nuclear factor, erythroid derived 2, like 2

increases expression

beta-Naphthoflavone results in increased expression of NFE2L2 protein

NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985

G

nuclear factor, erythroid derived 2, like 3

increases expression

beta-Naphthoflavone results in increased expression of NFE2L3 mRNA

NCBI chr 6:51,409,649...51,435,752
Ensembl chr 6:51,409,650...51,435,748

G

nuclear factor, interleukin 3, regulated

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NFIL3 mRNA

NCBI chr13:53,121,245...53,136,914
Ensembl chr13:53,121,245...53,135,109

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFKBIA mRNA]
beta-Naphthoflavone results in increased expression of NFKBIA mRNA

PMID:20045035 PMID:32151702

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon

increases expression

beta-Naphthoflavone results in increased expression of NFKBIE mRNA

NCBI chr17:45,866,626...45,874,095
Ensembl chr17:45,866,629...45,874,095

G

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta

increases expression

beta-Naphthoflavone results in increased expression of NFKBIZ mRNA

NCBI chr16:55,631,740...55,659,018
Ensembl chr16:55,631,738...55,659,262

G

nitrogen fixation gene 1 (S. cerevisiae)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NFS1 mRNA

NCBI chr 2:155,965,569...155,986,106
Ensembl chr 2:155,965,559...155,986,106

G

neuroglobin

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of NGB mRNA

NCBI chr12:87,144,305...87,149,313
Ensembl chr12:87,144,305...87,149,313

G

nidogen 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NID2 mRNA

NCBI chr14:19,801,325...19,861,855
Ensembl chr14:19,801,333...19,861,855

G

NIPA-like domain containing 4

decreases expression

beta-Naphthoflavone results in decreased expression of NIPAL4 mRNA

NCBI chr11:46,038,982...46,057,186
Ensembl chr11:46,038,982...46,057,335

G

nicotinamide nucleotide adenylyltransferase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NMNAT3 mRNA

NCBI chr 9:98,169,487...98,302,586
Ensembl chr 9:98,169,488...98,302,491

G

nicotinamide riboside kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of NMRK2 mRNA

NCBI chr10:81,034,004...81,037,871
Ensembl chr10:81,034,004...81,037,885

G

nocturnin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOCT mRNA

NCBI chr 3:51,131,868...51,159,075
Ensembl chr 3:51,131,868...51,159,065

G

nucleolar protein 3 (apoptosis repressor with CARD domain)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOL3 mRNA

NCBI chr 8:106,002,777...106,008,571
Ensembl chr 8:106,002,772...106,008,571

G

nodal modulator 1

increases expression

beta-Naphthoflavone results in increased expression of NOMO1 mRNA

NCBI chr 7:45,683,120...45,733,636
Ensembl chr 7:45,683,122...45,733,636

G

nitric oxide synthase 2, inducible

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NOS2 mRNA]

NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080

G

nitric oxide synthase 3, endothelial cell

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of NOS3 mRNA
beta-Naphthoflavone results in decreased expression of NOS3 protein
[Triclosan co-treated with beta-Naphthoflavone] results in decreased expression of NOS3 protein

PMID:32858204 PMID:33722737

NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472

G

notch 1

increases expression

beta-Naphthoflavone results in increased expression of NOTCH1 mRNA

NCBI chr 2:26,347,914...26,393,834
Ensembl chr 2:26,347,915...26,406,675

G

NADPH oxidase 4

increases expression

beta-Naphthoflavone results in increased expression of NOX4 mRNA

NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918

G

neural proliferation, differentiation and control 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NPDC1 mRNA

NCBI chr 2:25,293,067...25,299,504
Ensembl chr 2:25,289,363...25,299,506

G

nephronophthisis 1 (juvenile) homolog (human)

increases expression

beta-Naphthoflavone results in increased expression of NPHP1 mRNA

NCBI chr 2:127,582,652...127,630,833
Ensembl chr 2:127,582,652...127,630,817

G

natriuretic peptide type A

increases expression

beta-Naphthoflavone results in increased expression of NPPA mRNA

NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536

G

natriuretic peptide type B

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of NPPB mRNA
beta-Naphthoflavone results in decreased expression of NPPB mRNA

PMID:19969063 PMID:32858204

NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662

G

NAD(P)H dehydrogenase, quinone 1

increases expression
increases activity
multiple interactions

beta-Naphthoflavone results in increased expression of NQO1 mRNA; beta-Naphthoflavone results in increased expression of NQO1 protein
beta-Naphthoflavone results in increased activity of NQO1 protein
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of NQO1 mRNA; [beta-Naphthoflavone results in increased expression of NQO1 protein] inhibits the reaction [CYP1A1 gene mutant form results in increased susceptibility to Oxygen]; [beta-Naphthoflavone results in increased expression of NQO1 protein] which results in decreased susceptibility to Oxygen; beta-Naphthoflavone affects the reaction [Oxygen results in increased expression of NQO1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of NQO1 mRNA]; beta-Naphthoflavone promotes the reaction [Oxygen results in increased expression of NQO1 protein]; Cadmium inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased activity of NQO1 protein]; Chromium inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Lipopolysaccharides inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]; Oxygen inhibits the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]; Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NQO1 mRNA
beta-Naphthoflavone promotes the reaction [FOS protein binds to NQO1 promoter]; beta-Naphthoflavone promotes the reaction [JUN protein binds to NQO1 promoter]; CYP1A2 gene mutant form inhibits the reaction [Oxygen promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 protein]]; CYP1A2 gene mutant form promotes the reaction [beta-Naphthoflavone results in increased expression of NQO1 mRNA]

PMID:8375015 PMID:14510636 PMID:15337587 PMID:15627257 PMID:16906435 More...

NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838

G

N-ribosyldihydronicotinamide quinone reductase 2

increases expression

beta-Naphthoflavone results in increased expression of NQO2 mRNA

NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426

G

nuclear receptor subfamily 1, group D, member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NR1D1 mRNA

NCBI chr11:98,658,758...98,666,233
Ensembl chr11:98,658,758...98,666,159

G

nuclear receptor subfamily 1, group D, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NR1D2 mRNA

NCBI chr14:4,230,549...4,265,639
Ensembl chr14:4,230,569...4,265,642

G

nuclear receptor subfamily 1, group H, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H2 mRNA

NCBI chr 7:44,199,040...44,204,928
Ensembl chr 7:44,199,040...44,203,375

G

nuclear receptor subfamily 1, group H, member 3

decreases expression

beta-Naphthoflavone results in decreased expression of NR1H3 mRNA

NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179

G

nuclear receptor subfamily 1, group H, member 4

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NR1H4 mRNA
beta-Naphthoflavone results in decreased expression of NR1H4 mRNA

PMID:18164116 PMID:19737606

NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447

G

nuclear receptor subfamily 1, group I, member 2

decreases expression
increases activity
multiple interactions

beta-Naphthoflavone results in decreased expression of NR1I2 mRNA
beta-Naphthoflavone results in increased activity of NR1I2 protein
NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]; Pregnenolone Carbonitrile promotes the reaction [NR1I2 protein inhibits the reaction [beta-Naphthoflavone results in increased expression of AHR mRNA]]

PMID:20607812 PMID:25680588 PMID:28428138

NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186

G

nuclear receptor subfamily 1, group I, member 3

increases expression

beta-Naphthoflavone results in increased expression of NR1I3 mRNA

PMID:17627975 PMID:25949234

NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270

G

nuclear receptor subfamily 2, group F, member 1

affects binding

[beta-Naphthoflavone binds to AHR protein] which binds to NR2F1 protein

NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876

G

neuregulin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NRG1 mRNA

NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825

G

neurturin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NRTN mRNA

NCBI chr17:57,058,323...57,064,548
Ensembl chr17:57,058,325...57,064,530

G

NAD(P) dependent steroid dehydrogenase-like

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of NSDHL mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of NSDHL mRNA]

NCBI chr X:71,962,127...72,002,134
Ensembl chr X:71,962,163...72,002,120

G

NSFL1 (p97) cofactor (p47)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of NSFL1C mRNA

NCBI chr 2:151,336,102...151,353,230
Ensembl chr 2:151,336,102...151,353,334

G

5' nucleotidase, ecto

decreases expression

beta-Naphthoflavone results in decreased expression of NT5E mRNA

NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145

G

neurotrophin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NTF3 mRNA

NCBI chr 6:126,078,375...126,143,703
Ensembl chr 6:126,078,375...126,143,873

G

NUAK family, SNF1-like kinase, 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of NUAK2 mRNA

NCBI chr 1:132,243,827...132,261,233
Ensembl chr 1:132,243,864...132,261,226

G

nuclear protein transcription regulator 1

increases expression

beta-Naphthoflavone results in increased expression of NUPR1 mRNA

NCBI chr 7:126,222,418...126,224,642
Ensembl chr 7:126,222,421...126,230,033

G

2'-5' oligoadenylate synthetase 1G

decreases expression

beta-Naphthoflavone results in decreased expression of OAS1 mRNA

NCBI chr 5:121,014,205...121,025,676
Ensembl chr 5:121,014,205...121,025,676

G

2'-5' oligoadenylate synthetase-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OASL1 mRNA

NCBI chr 5:115,061,236...115,075,970
Ensembl chr 5:115,061,299...115,075,974

G

occludin

increases expression

beta-Naphthoflavone results in increased expression of OCLN mRNA

NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226

G

odontogenesis associated phosphoprotein

decreases expression

beta-Naphthoflavone results in decreased expression of ODAPH mRNA

NCBI chr 5:92,135,332...92,143,176
Ensembl chr 5:92,135,334...92,143,179

G

olfactomedin-like 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of OLFML1 mRNA

NCBI chr 7:107,166,640...107,190,572
Ensembl chr 7:107,166,653...107,190,301

G

olfactory receptor family 51 subfamily E member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OLR59 mRNA

NCBI chr 7:102,389,928...102,408,678
Ensembl chr 7:102,387,718...102,408,678

G

olfactory receptor family 5 subfamily M member 11B

increases expression

beta-Naphthoflavone results in increased expression of OR5M11B mRNA

NCBI chr 2:85,805,557...85,806,617
Ensembl chr 2:85,804,239...85,809,257

G

orosomucoid 1

increases expression

beta-Naphthoflavone results in increased expression of ORM1 mRNA

NCBI chr 4:63,262,793...63,266,400
Ensembl chr 4:63,262,797...63,266,400

G

oxidative stress induced growth inhibitor 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of OSGIN1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of OSGIN1 mRNA

PMID:18164116 PMID:19737606 PMID:32858204

NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995

G

prolyl 3-hydroxylase 2

decreases expression

beta-Naphthoflavone results in decreased expression of P3H2 mRNA

NCBI chr16:25,778,034...25,924,563
Ensembl chr16:25,778,038...25,924,534

G

phenylalanine hydroxylase

decreases expression

beta-Naphthoflavone results in decreased expression of PAH mRNA

NCBI chr10:87,357,657...87,419,999
Ensembl chr10:87,357,657...87,419,998

G

pannexin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PANX2 mRNA

NCBI chr15:88,941,797...88,957,769
Ensembl chr15:88,943,937...88,957,770

G

pregnancy-associated plasma protein A

decreases expression

beta-Naphthoflavone results in decreased expression of PAPPA mRNA

NCBI chr 4:65,041,993...65,276,776
Ensembl chr 4:65,042,411...65,275,746

G

protocadherin alpha 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCDHA4 mRNA

NCBI chr18:37,085,742...37,320,710
Ensembl chr18:37,085,701...37,320,714

G

protocadherin beta 19

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCDHB12 mRNA

NCBI chr18:37,630,049...37,637,181
Ensembl chr18:37,630,044...37,637,181

G

PCNA clamp associated factor

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCLAF mRNA
beta-Naphthoflavone results in decreased expression of PCLAF mRNA

PMID:18164116 PMID:32858204

NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548

G

proliferating cell nuclear antigen

increases expression

beta-Naphthoflavone results in increased expression of PCNA protein

NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234

G

procollagen C-endopeptidase enhancer protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCOLCE mRNA

NCBI chr 5:137,603,369...137,609,666
Ensembl chr 5:137,603,365...137,612,046

G

Purkinje cell protein 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCP4 mRNA

NCBI chr16:96,268,806...96,326,993
Ensembl chr16:96,268,806...96,326,993

G

proprotein convertase subtilisin/kexin type 9

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PCSK9 mRNA
beta-Naphthoflavone results in decreased expression of PCSK9 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PCSK9 mRNA]

PMID:18164116 PMID:22234961

NCBI chr 4:106,299,531...106,321,522
Ensembl chr 4:106,299,526...106,321,526

G

pyruvate carboxylase

increases expression

beta-Naphthoflavone results in increased expression of PC mRNA

NCBI chr19:4,560,500...4,671,780
Ensembl chr19:4,560,500...4,671,780

G

platelet derived growth factor, alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PDGFA mRNA

NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125

G

pyruvate dehydrogenase kinase, isoenzyme 4

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PDK4 mRNA
beta-Naphthoflavone results in increased expression of PDK4 mRNA

PMID:18164116 PMID:32858204

NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309

G

PDZ and LIM domain 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PDLIM3 mRNA

NCBI chr 8:46,338,524...46,372,672
Ensembl chr 8:46,338,498...46,372,585

G

PDZ domain containing RING finger 3

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of PDZRN3 mRNA

NCBI chr 6:101,126,568...101,354,858
Ensembl chr 6:101,126,570...101,354,858

G

pelota mRNA surveillance and ribosome rescue factor

increases expression

beta-Naphthoflavone results in increased expression of PELO mRNA

NCBI chr13:115,224,891...115,226,694
Ensembl chr13:115,224,891...115,226,722

G

period circadian clock 1

multiple interactions
decreases expression

beta-Naphthoflavone inhibits the reaction [CLOCK protein binds to PER1 promoter]; beta-Naphthoflavone inhibits the reaction [Colforsin results in increased expression of PER1 mRNA]; beta-Naphthoflavone promotes the reaction [AHR protein binds to PER1 promoter]
beta-Naphthoflavone results in decreased expression of PER1 mRNA; beta-Naphthoflavone results in decreased expression of PER1 protein

PMID:20106950 PMID:23291558

NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786

G

period circadian clock 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PER2 mRNA

NCBI chr 1:91,343,699...91,387,028
Ensembl chr 1:91,343,704...91,387,046

G

peroxisomal biogenesis factor 11 alpha

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PEX11A mRNA

NCBI chr 7:79,385,705...79,392,879
Ensembl chr 7:79,385,705...79,392,879

G

platelet factor 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PF4 mRNA

NCBI chr 5:90,920,362...90,921,242
Ensembl chr 5:90,920,294...90,921,242

G

phosphofructokinase, liver, B-type

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PFKL mRNA

NCBI chr10:77,822,781...77,845,641
Ensembl chr10:77,822,781...77,845,917

G

profilin 2

increases expression

beta-Naphthoflavone results in increased expression of PFN2 mRNA

NCBI chr 3:57,749,316...57,755,178
Ensembl chr 3:57,749,316...57,755,500

G

post-GPI attachment to proteins 3

decreases expression

beta-Naphthoflavone results in decreased expression of PGAP3 mRNA

NCBI chr11:98,279,498...98,292,022
Ensembl chr11:98,279,503...98,291,316

G

pyroglutamyl-peptidase I

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PGPEP1 mRNA

NCBI chr 8:71,099,086...71,113,096
Ensembl chr 8:71,099,085...71,113,038

G

3-phosphoglycerate dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of PHGDH mRNA

NCBI chr 3:98,220,487...98,247,285
Ensembl chr 3:98,220,486...98,247,306

G

pleckstrin homology like domain, family A, member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PHLDA3 mRNA

NCBI chr 1:135,693,823...135,696,872
Ensembl chr 1:135,693,857...135,696,874

G

phosphatase, orphan 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of PHOSPHO1 mRNA

NCBI chr11:95,715,326...95,722,966
Ensembl chr11:95,715,325...95,722,966

G

phosphatidylinositol-5-phosphate 4-kinase, type II, gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PIP4K2C mRNA

NCBI chr10:127,032,936...127,047,508
Ensembl chr10:127,032,936...127,047,454

G

pirin

increases expression

beta-Naphthoflavone results in increased expression of PIR mRNA

NCBI chr X:163,052,427...163,156,009
Ensembl chr X:163,052,367...163,156,007

G

paired-like homeodomain transcription factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PITX1 mRNA

NCBI chr13:55,972,857...55,984,002
Ensembl chr13:55,972,864...55,984,005

G

Pbx/knotted 1 homeobox

increases expression

beta-Naphthoflavone results in increased expression of PKNOX1 mRNA

NCBI chr17:31,783,697...31,826,665
Ensembl chr17:31,783,708...31,826,667

G

phospholipase A1 member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLA1A mRNA

NCBI chr16:38,214,245...38,253,553
Ensembl chr16:38,216,479...38,253,507

G

phospholipase A2, group IB, pancreas

decreases expression

beta-Naphthoflavone results in decreased expression of PLA2G1B mRNA

NCBI chr 5:115,604,201...115,612,781
Ensembl chr 5:115,604,321...115,612,781

G

phospholipase A2, group IIC

increases expression

beta-Naphthoflavone results in increased expression of PLA2G2C mRNA

NCBI chr 4:138,452,636...138,471,886
Ensembl chr 4:138,452,103...138,473,443

G

phospholipase A2, group IVA (cytosolic, calcium-dependent)

increases expression

beta-Naphthoflavone results in increased expression of PLA2G4A mRNA

NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041

G

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLA2G7 mRNA

NCBI chr17:43,879,009...43,923,093
Ensembl chr17:43,878,989...43,923,092

G

placental specific protein 1

decreases expression

beta-Naphthoflavone results in decreased expression of PLAC1 mRNA

NCBI chr X:52,158,870...52,328,969
Ensembl chr X:52,158,872...52,328,988

G

plasminogen activator, tissue

increases expression

beta-Naphthoflavone results in increased expression of PLAT mRNA

NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860

G

plasminogen activator, urokinase

increases expression

beta-Naphthoflavone results in increased expression of PLAU mRNA

NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453

G

plasminogen activator, urokinase receptor

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of PLAUR mRNA
beta-Naphthoflavone results in decreased expression of PLAUR mRNA

PMID:32151702 PMID:32858204

NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393

G

phospholipase C, delta 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLCD1 mRNA

NCBI chr 9:118,900,595...118,922,570
Ensembl chr 9:118,900,595...118,922,570

G

phospholipase D2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PLD2 mRNA

NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936

G

pleckstrin

decreases expression

beta-Naphthoflavone results in decreased expression of PLEK mRNA

NCBI chr11:16,921,206...16,958,718
Ensembl chr11:16,921,206...17,002,381

G

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLEKHA4 mRNA

NCBI chr 7:45,175,754...45,203,653
Ensembl chr 7:45,175,754...45,203,653

G

perilipin 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PLIN2 mRNA

NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297

G

polo like kinase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLK mRNA

NCBI chr 7:121,758,658...121,769,107
Ensembl chr 7:121,758,662...121,769,096

G

procollagen lysine, 2-oxoglutarate 5-dioxygenase 2

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLOD2 mRNA
beta-Naphthoflavone results in decreased expression of PLOD2 mRNA

PMID:18164116 PMID:32858204

NCBI chr 9:92,421,828...92,490,481
Ensembl chr 9:92,424,276...92,490,481

G

phospholipid scramblase 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of PLSCR1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PLSCR1 mRNA

PMID:18164116 PMID:19737545

NCBI chr 9:92,132,265...92,154,034
Ensembl chr 9:92,131,803...92,154,331

G

peripheral myelin protein 22

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PMP22 mRNA

NCBI chr11:63,019,808...63,050,373
Ensembl chr11:63,019,808...63,050,373

G

phosphomevalonate kinase

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of PMVK mRNA]

NCBI chr 3:89,361,848...89,376,321
Ensembl chr 3:89,361,848...89,376,320

G

prepronociceptin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PNOC mRNA

NCBI chr14:65,638,931...65,662,908
Ensembl chr14:65,638,122...65,662,921

G

proline-rich nuclear receptor coactivator 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PNRC1 mRNA

NCBI chr 4:33,245,423...33,248,787
Ensembl chr 4:33,245,423...33,290,163

G

protein O-glucosyltransferase 3

decreases expression

beta-Naphthoflavone results in decreased expression of POGLUT3 mRNA

NCBI chr 9:53,294,217...53,313,167
Ensembl chr 9:53,295,325...53,313,167

G

polymerase (DNA directed), beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POLB mRNA

NCBI chr 8:23,118,135...23,143,482
Ensembl chr 8:23,118,142...23,143,451

G

cytochrome p450 oxidoreductase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of POR mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of POR mRNA; [Phenobarbital co-treated with beta-Naphthoflavone] results in increased expression of POR protein

PMID:18164116 PMID:19737545 PMID:21295105 PMID:30842367

NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180

G

POU domain, class 3, transcription factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of POU3F1 mRNA

NCBI chr 4:124,551,439...124,554,448
Ensembl chr 4:124,550,600...124,554,448

G

peroxisome proliferator activated receptor alpha

multiple interactions
increases expression

AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]; AHR affects the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; alpha-naphthoflavone inhibits the reaction [beta-Naphthoflavone results in increased expression of PPARA protein]; BMAL1 affects the reaction [beta-Naphthoflavone results in increased expression of PPARA mRNA]
beta-Naphthoflavone results in increased expression of PPARA mRNA; beta-Naphthoflavone results in increased expression of PPARA protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARA mRNA

PMID:18164116 PMID:21849270

NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020

G

peroxisome proliferator activator receptor delta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PPARD mRNA

NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448

G

peroxisome proliferator activated receptor gamma

multiple interactions

beta-Naphthoflavone inhibits the reaction [Triclosan results in increased expression of PPARG protein]

NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360

G

PTPRF interacting protein, binding protein 2 (liprin beta 2)

decreases expression

beta-Naphthoflavone results in decreased expression of PPFIBP2 mRNA

NCBI chr 7:107,192,608...107,347,790
Ensembl chr 7:107,194,414...107,347,790

G

peptidylprolyl isomerase (cyclophilin)-like 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PPIL2 mRNA

NCBI chr16:16,904,419...16,929,126
Ensembl chr16:16,904,419...16,929,121

G

protein phosphatase 1F (PP2C domain containing)

decreases expression

beta-Naphthoflavone results in decreased expression of PPM1F mRNA

NCBI chr16:16,714,314...16,745,239
Ensembl chr16:16,714,333...16,745,228

G

protein phosphatase 1, regulatory inhibitor subunit 14C

decreases expression

beta-Naphthoflavone results in decreased expression of PPP1R14C mRNA

NCBI chr10:3,315,974...3,414,975
Ensembl chr10:3,316,057...3,414,975

G

protein phosphatase 2, regulatory subunit B', epsilon

increases expression

beta-Naphthoflavone results in increased expression of PPP2R5E mRNA

NCBI chr12:75,496,237...75,643,064
Ensembl chr12:75,497,655...75,643,019

G

protein phosphatase 4, regulatory subunit 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PPP4R1 mRNA

NCBI chr17:66,089,253...66,148,921
Ensembl chr17:66,089,568...66,148,921

G

proteoglycan 2, bone marrow

decreases expression

beta-Naphthoflavone results in decreased expression of PRG2 mRNA

NCBI chr 2:84,810,805...84,813,977
Ensembl chr 2:84,810,805...84,813,976

G

prolactin

multiple interactions
decreases expression

alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of PRL mRNA]
beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CSN2 mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of LALBA mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of WAP mRNA]; beta-Naphthoflavone promotes the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of CYP1A1 mRNA]

PMID:22975028 PMID:29521512

NCBI chr13:27,241,553...27,249,187
Ensembl chr13:27,241,553...27,249,188

G

prolactin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PRLR mRNA

NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266

G

prominin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PROM1 mRNA

NCBI chr 5:44,150,963...44,260,850
Ensembl chr 5:44,150,962...44,259,374

G

serine protease 8 (prostasin)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PRSS8 mRNA

NCBI chr 7:127,524,889...127,529,266
Ensembl chr 7:127,524,888...127,529,276

G

phosphoserine aminotransferase 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PSAT1 mRNA
beta-Naphthoflavone results in increased expression of PSAT1 mRNA

PMID:18164116 PMID:32858204

NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701

G

proteasome (prosome, macropain) subunit, beta type 5

increases activity
increases expression

beta-Naphthoflavone results in increased activity of PSMB5 protein
beta-Naphthoflavone results in increased expression of PSMB5 protein

NCBI chr14:54,851,577...54,855,452
Ensembl chr14:54,851,576...54,855,479

G

protease (prosome, macropain) 26S subunit, ATPase 1

increases expression

beta-Naphthoflavone results in increased expression of PSMC1 mRNA

NCBI chr12:100,076,461...100,089,623
Ensembl chr12:100,076,413...100,089,664

G

proteasome (prosome, macropain) 26S subunit, ATPase 2

increases expression

beta-Naphthoflavone results in increased expression of PSMC2 mRNA

NCBI chr 5:21,990,273...22,008,785
Ensembl chr 5:21,990,281...22,008,785

G

proteasome (prosome, macropain) 26S subunit, ATPase, 4

increases expression

beta-Naphthoflavone results in increased expression of PSMC4 mRNA

NCBI chr 7:27,741,127...27,749,517
Ensembl chr 7:27,741,132...27,749,526

G

proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

increases expression

beta-Naphthoflavone results in increased expression of PSMD13 mRNA

NCBI chr 7:140,462,307...140,478,555
Ensembl chr 7:140,461,881...140,478,556

G

prostaglandin D2 synthase (brain)

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGDS mRNA

NCBI chr 2:25,356,723...25,360,080
Ensembl chr 2:25,356,721...25,360,058

G

prostaglandin F receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of PTGFR mRNA

NCBI chr 3:151,504,247...151,543,165
Ensembl chr 3:151,502,139...151,543,267

G

prostaglandin reductase 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of PTGR1 mRNA

NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119

G

prostaglandin-endoperoxide synthase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of PTGS2 mRNA; beta-Naphthoflavone results in increased expression of PTGS2 protein
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA; [Omeprazole co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 mRNA]; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTGS2 protein]

PMID:18164116 PMID:20045035 PMID:22687991 PMID:23038005

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

G

pleiotrophin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTN mRNA

NCBI chr 6:36,691,863...36,787,114
Ensembl chr 6:36,691,864...36,787,155

G

protein tyrosine phosphatase, non-receptor type 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTPN3 mRNA

NCBI chr 4:57,190,841...57,339,036
Ensembl chr 4:57,190,841...57,301,837

G

pituitary tumor-transforming gene 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of PTTG1 mRNA
beta-Naphthoflavone results in decreased expression of PTTG1 mRNA

PMID:18164116 PMID:32858204

NCBI chr11:43,311,097...43,317,417
Ensembl chr11:43,311,077...43,317,078

G

quinolinate phosphoribosyltransferase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of QPRT mRNA
beta-Naphthoflavone results in decreased expression of QPRT mRNA

PMID:18164116 PMID:32858204

NCBI chr 7:126,706,942...126,721,201
Ensembl chr 7:126,706,286...126,721,398

G

RAB11 family interacting protein 5 (class I)

decreases expression

beta-Naphthoflavone results in decreased expression of RAB11FIP5 mRNA

NCBI chr 6:85,311,944...85,351,663
Ensembl chr 6:85,311,944...85,351,616

G

retinoic acid induced 14

decreases expression

beta-Naphthoflavone results in decreased expression of RAI14 mRNA

NCBI chr15:10,569,057...10,719,353
Ensembl chr15:10,569,055...10,714,710

G

Rap1 GTPase-activating protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RAP1GAP mRNA

NCBI chr 4:137,391,549...137,457,172
Ensembl chr 4:137,392,037...137,457,172

G

RAS, dexamethasone-induced 1

increases expression

beta-Naphthoflavone results in increased expression of RASD1 mRNA

NCBI chr11:59,854,007...59,855,770
Ensembl chr11:59,854,007...59,855,770

G

RAS-like, family 11, member B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RASL11B mRNA

NCBI chr 5:74,355,987...74,360,138
Ensembl chr 5:74,355,947...74,360,142

G

Ras association (RalGDS/AF-6) domain family member 4

decreases expression

beta-Naphthoflavone results in decreased expression of RASSF4 mRNA

NCBI chr 6:116,609,969...116,650,797
Ensembl chr 6:116,609,969...116,650,913

G

RB transcriptional corepressor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RB1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RB1 mRNA

NCBI chr14:73,430,298...73,563,446
Ensembl chr14:73,421,113...73,563,262

G

RNA binding motif protein 33

increases expression

beta-Naphthoflavone results in increased expression of RBM33 mRNA

NCBI chr 5:28,521,817...28,624,242
Ensembl chr 5:28,522,119...28,624,237

G

retinol binding protein 4, plasma

increases expression

beta-Naphthoflavone results in increased expression of RBP4 mRNA

NCBI chr19:38,105,068...38,113,769
Ensembl chr19:38,105,077...38,113,729

G

regulator of calcineurin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RCAN1 mRNA

NCBI chr16:92,188,839...92,263,057
Ensembl chr16:92,188,841...92,267,755

G

regulator of calcineurin 2

multiple interactions
decreases expression

AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RCAN2 mRNA]

NCBI chr17:44,112,243...44,350,407
Ensembl chr17:44,112,242...44,350,407

G

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RCBTB1 mRNA

NCBI chr14:59,438,471...59,474,716
Ensembl chr14:59,438,658...59,474,714

G

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2

increases expression

beta-Naphthoflavone results in increased expression of RCBTB2 mRNA

NCBI chr14:73,376,185...73,421,495
Ensembl chr14:73,360,477...73,445,283

G

retinol dehydrogenase 11

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of RDH11 mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of RDH11 mRNA]

NCBI chr12:79,221,007...79,238,629
Ensembl chr12:79,221,111...79,239,067

G

receptor accessory protein 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of REEP6 mRNA

NCBI chr10:80,165,831...80,172,275
Ensembl chr10:80,165,787...80,172,275

G

regenerating islet-derived family, member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of REG4 mRNA

NCBI chr 3:98,129,454...98,144,064
Ensembl chr 3:98,129,472...98,144,064

G

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

multiple interactions

beta-Naphthoflavone inhibits the reaction [Triclosan results in decreased expression of RELA protein]

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

G

avian reticuloendotheliosis viral (v-rel) oncogene related B

increases expression

beta-Naphthoflavone results in increased expression of RELB mRNA

NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363

G

regulator of cell cycle

decreases expression

beta-Naphthoflavone results in decreased expression of RGCC mRNA

NCBI chr14:79,526,190...79,539,075
Ensembl chr14:79,526,196...79,539,085

G

regucalcin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RGN mRNA

NCBI chr X:20,413,980...20,428,328
Ensembl chr X:20,416,026...20,428,328

G

regulator of G-protein signaling 1

decreases expression

beta-Naphthoflavone results in decreased expression of RGS1 mRNA

NCBI chr 1:144,120,407...144,124,862
Ensembl chr 1:144,118,034...144,124,980

G

regulator of G-protein signalling 10

increases expression

beta-Naphthoflavone results in increased expression of RGS10 mRNA

NCBI chr 7:127,975,345...128,020,993
Ensembl chr 7:127,975,345...128,020,482

G

regulator of G-protein signaling 12

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RGS12 mRNA

NCBI chr 5:35,106,273...35,196,988
Ensembl chr 5:35,106,789...35,196,988

G

regulator of G-protein signaling 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RGS16 mRNA

NCBI chr 1:153,616,099...153,621,212
Ensembl chr 1:153,616,095...153,621,214

G

regulator of G-protein signaling 20

increases expression

beta-Naphthoflavone results in increased expression of RGS20 mRNA

NCBI chr 1:4,976,342...5,140,528
Ensembl chr 1:4,979,799...5,140,508

G

regulator of G-protein signaling 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RGS4 mRNA

NCBI chr 1:169,569,046...169,575,211
Ensembl chr 1:169,569,046...169,575,211

G

regulator of G-protein signaling 9

increases expression

beta-Naphthoflavone results in increased expression of RGS9 mRNA

NCBI chr11:109,116,174...109,189,013
Ensembl chr11:109,116,181...109,188,955

G

Rhesus blood group-associated B glycoprotein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RHBG mRNA

NCBI chr 3:88,150,181...88,162,046
Ensembl chr 3:88,150,181...88,162,016

G

Rho-related BTB domain containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of RHOBTB1 mRNA

NCBI chr10:68,987,106...69,127,621
Ensembl chr10:68,987,264...69,127,621

G

receptor (TNFRSF)-interacting serine-threonine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of RIPK2 mRNA

NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647

G

Ras-like without CAAX 1

increases expression

beta-Naphthoflavone results in increased expression of RIT1 mRNA

NCBI chr 3:88,624,154...88,638,354
Ensembl chr 3:88,624,145...88,638,356

G

ribonuclease T2A

decreases expression

beta-Naphthoflavone results in decreased expression of RNASET2 mRNA

NCBI chr17:8,347,412...8,367,078
Ensembl chr17:8,334,277...8,366,929

G

ring finger protein 24

increases expression

beta-Naphthoflavone results in increased expression of RNF24 mRNA

NCBI chr 2:131,139,984...131,194,766
Ensembl chr 2:131,139,984...131,194,812

G

ribosomal protein lateral stalk subunit P0

decreases expression
increases expression

beta-Naphthoflavone results in decreased expression of RPLP0 mRNA
beta-Naphthoflavone results in increased expression of RPLP0 mRNA

PMID:12883083 PMID:23994337

NCBI chr 5:115,697,526...115,701,788
Ensembl chr 5:115,697,526...115,701,786

G

ribosomal protein S6 kinase, polypeptide 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RPS6KA2 mRNA

NCBI chr17:7,356,384...7,570,714
Ensembl chr17:7,292,942...7,570,726

G

ribosomal protein S6 kinase, polypeptide 5

decreases expression

beta-Naphthoflavone results in decreased expression of RPS6KA5 mRNA

NCBI chr12:100,514,692...100,691,693
Ensembl chr12:100,514,698...100,693,242

G

ribosomal RNA processing 1B

increases expression

beta-Naphthoflavone results in increased expression of RRP1B mRNA

NCBI chr17:32,255,087...32,281,839
Ensembl chr17:32,255,074...32,281,839

G

rhotekin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RTKN mRNA

NCBI chr 6:83,112,485...83,129,560
Ensembl chr 6:83,112,444...83,129,560

G

reticulon 4

decreases expression

beta-Naphthoflavone results in decreased expression of RTN4 mRNA

NCBI chr11:29,642,898...29,694,414
Ensembl chr11:29,642,947...29,694,331

G

runt related transcription factor 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of RUNX3 mRNA

NCBI chr 4:134,847,956...134,905,301
Ensembl chr 4:134,847,963...134,905,301

G

retinoid X receptor gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of RXRG mRNA

NCBI chr 1:167,425,902...167,467,191
Ensembl chr 1:167,425,953...167,467,192

G

S100 calcium binding protein A4

increases expression

beta-Naphthoflavone results in increased expression of S100A4 mRNA

NCBI chr 3:90,511,077...90,513,349
Ensembl chr 3:90,511,078...90,513,352

G

S100 calcium binding protein A8 (calgranulin A)

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of S100A8 mRNA
beta-Naphthoflavone results in increased expression of S100A8 mRNA

PMID:18164116 PMID:32151702 PMID:32858204

NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342

G

S100 calcium binding protein A9 (calgranulin B)

increases expression

beta-Naphthoflavone results in increased expression of S100A9 mRNA

NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028

G

sphingosine-1-phosphate receptor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of S1PR1 mRNA

NCBI chr 3:115,504,082...115,508,704
Ensembl chr 3:115,504,082...115,508,721

G

stabilizer of axonemal microtubules 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SAXO4 mRNA

NCBI chr19:10,451,599...10,463,826
Ensembl chr19:10,451,599...10,460,292

G

spermine binding protein-like

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SBPL mRNA

NCBI chr17:24,172,059...24,174,247
Ensembl chr17:24,172,058...24,174,248

G

secretory carrier membrane protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCAMP1 mRNA

NCBI chr13:94,337,818...94,422,339
Ensembl chr13:94,337,818...94,422,365

G

stearoyl-Coenzyme A desaturase 1

decreases expression

beta-Naphthoflavone results in decreased expression of SCD1 mRNA

NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318

G

stearoyl-Coenzyme A desaturase 2

decreases expression

beta-Naphthoflavone results in decreased expression of SCD mRNA

NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303

G

schwannomin interacting protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCHIP1 mRNA

NCBI chr 3:67,972,135...68,533,815
Ensembl chr 3:67,972,135...68,533,814

G

sodium channel, type IV, beta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCN4B mRNA

NCBI chr 9:45,049,922...45,065,453
Ensembl chr 9:45,049,693...45,065,450

G

secernin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SCRN1 mRNA

NCBI chr 6:54,451,813...54,543,332
Ensembl chr 6:54,478,158...54,543,474

G

secretin receptor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SCTR mRNA

NCBI chr 1:119,934,710...119,991,269
Ensembl chr 1:119,934,624...119,991,266

G

syndecan 1

decreases expression

beta-Naphthoflavone results in decreased expression of SDC1 mRNA

NCBI chr12:8,821,396...8,843,716
Ensembl chr12:8,821,323...8,843,715

G

serine dehydratase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SDS mRNA

NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997

G

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

decreases expression

beta-Naphthoflavone results in decreased expression of SEMA3B mRNA

NCBI chr 9:107,474,868...107,486,440
Ensembl chr 9:107,474,873...107,486,428

G

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

increases expression

beta-Naphthoflavone results in increased expression of SEMA6B mRNA

NCBI chr17:56,430,085...56,447,343
Ensembl chr17:56,430,085...56,447,343

G

septin 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SEPTIN4 mRNA

NCBI chr11:87,457,515...87,481,365
Ensembl chr11:87,457,479...87,481,365

G

serine (or cysteine) peptidase inhibitor, clade A, member 3B

decreases expression

beta-Naphthoflavone results in decreased expression of SERPINA3 mRNA

NCBI chr12:104,094,245...104,105,805
Ensembl chr12:104,094,255...104,105,804

G

serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SERPINA4 mRNA
beta-Naphthoflavone results in decreased expression of SERPINA4 mRNA

PMID:18164116 PMID:19737606

NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983

G

serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SERPINA7 mRNA; AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SERPINA7 mRNA]

PMID:19737545 PMID:19737606 PMID:22234961

NCBI chr X:137,979,998...137,985,985
Ensembl chr X:137,980,006...137,985,985

G

serine (or cysteine) peptidase inhibitor, clade B, member 1a

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINB1A mRNA

NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168

G

serine (or cysteine) peptidase inhibitor, clade E, member 1

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of SERPINE1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA]

PMID:18164116 PMID:19737606 PMID:20045035 PMID:21295105 PMID:22687991

NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122

G

stratifin

increases expression

beta-Naphthoflavone results in increased expression of SFN mRNA

NCBI chr 4:133,327,867...133,329,163
Ensembl chr 4:133,327,867...133,329,479

G

SWI5 dependent recombination repair 1

increases expression

beta-Naphthoflavone results in increased expression of SFR1 mRNA

NCBI chr19:47,720,159...47,724,027
Ensembl chr19:47,720,121...47,724,027

G

secreted frizzled-related protein 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFRP1 mRNA
beta-Naphthoflavone results in decreased expression of SFRP1 mRNA

PMID:18164116 PMID:32858204

NCBI chr 8:23,901,401...23,939,648
Ensembl chr 8:23,901,518...23,939,648

G

sideroflexin 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SFXN3 mRNA

NCBI chr19:45,036,015...45,044,822
Ensembl chr19:45,035,942...45,044,822

G

serum/glucocorticoid regulated kinase 2

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of SGK2 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SGK2 mRNA

PMID:18164116 PMID:19737606

NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047

G

SH2 domain containing 5

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of SH2D5 mRNA
beta-Naphthoflavone results in decreased expression of SH2D5 mRNA

PMID:19737606 PMID:32858204

NCBI chr 4:137,977,722...137,988,279
Ensembl chr 4:137,977,714...137,988,643

G

SLAM family member 7

decreases expression

beta-Naphthoflavone results in decreased expression of SLAMF7 mRNA

NCBI chr 1:171,458,506...171,480,522
Ensembl chr 1:171,459,971...171,480,603

G

solute carrier family 10 (sodium/bile acid cotransporter family), member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SLC10A1 mRNA

NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479

G

solute carrier family 13 (sodium-dependent citrate transporter), member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC13A5 mRNA

NCBI chr11:72,132,816...72,158,092
Ensembl chr11:72,132,815...72,158,048

G

solute carrier family 16 (monocarboxylic acid transporters), member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC16A1 mRNA

NCBI chr 3:104,545,980...104,565,778
Ensembl chr 3:104,545,984...104,565,778

G

solute carrier family 16 (monocarboxylic acid transporters), member 10

decreases expression

beta-Naphthoflavone results in decreased expression of SLC16A10 mRNA

NCBI chr10:39,909,528...40,018,262
Ensembl chr10:39,909,528...40,018,254

G

solute carrier family 16 (monocarboxylic acid transporters), member 4

decreases expression

beta-Naphthoflavone results in decreased expression of SLC16A4 mRNA

NCBI chr 3:107,198,543...107,219,437
Ensembl chr 3:107,198,546...107,219,431

G

solute carrier family 16 (monocarboxylic acid transporters), member 6

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC16A6 mRNA
beta-Naphthoflavone results in increased expression of SLC16A6 mRNA

PMID:18164116 PMID:19737606

NCBI chr11:109,341,681...109,366,428
Ensembl chr11:109,341,681...109,364,424

G

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC17A6 mRNA

NCBI chr 7:51,271,578...51,320,874
Ensembl chr 7:51,271,754...51,320,867

G

solute carrier family 19 (thiamine transporter), member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC19A2 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC19A2 mRNA

NCBI chr 1:164,076,615...164,092,954
Ensembl chr 1:164,076,615...164,092,954

G

solute carrier family 19, member 3

decreases expression

beta-Naphthoflavone results in decreased expression of SLC19A3 mRNA

NCBI chr 1:82,990,242...83,016,541
Ensembl chr 1:82,990,244...83,016,169

G

solute carrier family 1 (glutamate/neutral amino acid transporter), member 4

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of SLC1A4 mRNA

NCBI chr11:20,252,180...20,282,713
Ensembl chr11:20,252,180...20,282,713

G

solute carrier family 1 (neutral amino acid transporter), member 5

increases expression

beta-Naphthoflavone results in increased expression of SLC1A5 mRNA

NCBI chr 7:16,515,259...16,532,199
Ensembl chr 7:16,515,265...16,532,199

G

solute carrier family 20, member 1

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC20A1 mRNA
beta-Naphthoflavone results in increased expression of SLC20A1 mRNA

PMID:18164116 PMID:19737606

NCBI chr 2:129,038,662...129,053,535
Ensembl chr 2:129,040,684...129,053,536

G

solute carrier family 22 (organic cation transporter), member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SLC22A1 mRNA

NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716

G

solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC25A29 mRNA

NCBI chr12:108,791,804...108,801,802
Ensembl chr12:108,791,799...108,801,809

G

solute carrier family 25, member 36

increases expression

beta-Naphthoflavone results in increased expression of SLC25A36 mRNA

NCBI chr 9:96,957,014...96,993,094
Ensembl chr 9:96,957,014...96,993,210

G

solute carrier family 27 (fatty acid transporter), member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC27A2 mRNA

NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163

G

solute carrier family 2 (facilitated glucose transporter), member 1

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC2A1 protein
beta-Naphthoflavone results in decreased expression of SLC2A1 mRNA

PMID:28903497 PMID:29521512 PMID:32858204

NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180

G

solute carrier family 2 (facilitated glucose transporter), member 5

decreases expression

beta-Naphthoflavone results in decreased expression of SLC2A5 mRNA

NCBI chr 4:150,203,801...150,228,625
Ensembl chr 4:150,203,740...150,228,626

G

solute carrier family 2, (facilitated glucose transporter), member 8

increases expression

beta-Naphthoflavone results in increased expression of SLC2A8 mRNA

NCBI chr 2:32,862,993...32,872,088
Ensembl chr 2:32,863,002...32,872,095

G

solute carrier family 30, member 10

decreases expression

beta-Naphthoflavone results in decreased expression of SLC30A10 mRNA

NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959

G

solute carrier family 30 (zinc transporter), member 2

decreases expression

beta-Naphthoflavone results in decreased expression of SLC30A2 mRNA

NCBI chr 4:134,070,357...134,081,795
Ensembl chr 4:134,070,492...134,081,795

G

solute carrier family 34 (sodium phosphate), member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC34A2 mRNA

NCBI chr 5:53,206,695...53,229,006
Ensembl chr 5:53,195,423...53,229,006

G

solute carrier family 35, member B2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC35B2 mRNA

NCBI chr17:45,874,844...45,878,597
Ensembl chr17:45,874,800...45,878,597

G

solute carrier family 38, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC38A2 mRNA

NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611

G

solute carrier family 38, member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC38A4 mRNA

NCBI chr15:96,892,701...96,953,837
Ensembl chr15:96,892,701...96,953,837

G

solute carrier family 39 (metal ion transporter), member 5

decreases expression

beta-Naphthoflavone results in decreased expression of SLC39A5 mRNA

NCBI chr10:128,231,796...128,237,145
Ensembl chr10:128,231,800...128,237,098

G

solute carrier family 39 (metal ion transporter), member 8

decreases expression

beta-Naphthoflavone results in decreased expression of SLC39A8 mRNA

NCBI chr 3:135,522,644...135,594,333
Ensembl chr 3:135,531,040...135,594,333

G

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC3A2 mRNA

NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733

G

solute carrier family 43, member 2

decreases expression

beta-Naphthoflavone results in decreased expression of SLC43A2 mRNA

NCBI chr11:75,420,741...75,468,401
Ensembl chr11:75,422,520...75,468,401

G

solute carrier family 44, member 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC44A4 mRNA

NCBI chr17:35,133,200...35,149,412
Ensembl chr17:35,133,442...35,149,412

G

solute carrier family 48 (heme transporter), member 1

increases expression

beta-Naphthoflavone results in increased expression of SLC48A1 mRNA

NCBI chr15:97,682,246...97,690,573
Ensembl chr15:97,676,401...97,690,573

G

solute carrier family 4 (anion exchanger), member 1

decreases expression

beta-Naphthoflavone results in decreased expression of SLC4A1 mRNA

NCBI chr11:102,239,646...102,256,107
Ensembl chr11:102,239,650...102,257,029

G

solute carrier family 66 member 2

increases expression

beta-Naphthoflavone results in increased expression of SLC66A2 mRNA

NCBI chr18:80,298,458...80,335,940
Ensembl chr18:80,296,507...80,335,940

G

solute carrier family 66 member 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC66A3 mRNA

NCBI chr12:17,038,649...17,050,385
Ensembl chr12:17,038,649...17,050,409

G

solute carrier family 6 (neurotransmitter transporter), member 20B

increases expression

beta-Naphthoflavone results in increased expression of SLC6A20 mRNA

NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630

G

solute carrier family 6 (neurotransmitter transporter, taurine), member 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLC6A6 mRNA

NCBI chr 6:91,661,031...91,736,044
Ensembl chr 6:91,661,034...91,736,047

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SLC7A1 mRNA

NCBI chr 5:148,264,220...148,336,714
Ensembl chr 5:148,264,220...148,336,714

G

solute carrier family 7 (cationic amino acid transporter, y+ system), member 5

increases expression

beta-Naphthoflavone results in increased expression of SLC7A5 mRNA

NCBI chr 8:122,607,885...122,634,425
Ensembl chr 8:122,607,889...122,634,433

G

solute carrier organic anion transporter family, member 1a4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SLCO1A4 mRNA

NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925

G

solute carrier organic anion transporter family, member 2b1

increases expression

beta-Naphthoflavone results in increased expression of SLCO2B1 mRNA

NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547

G

solute carrier organic anion transporter family, member 3a1

increases expression

beta-Naphthoflavone results in increased expression of SLCO3A1 mRNA

NCBI chr 7:73,925,166...74,204,528
Ensembl chr 7:73,925,167...74,204,528

G

SMAD family member 6

decreases expression

beta-Naphthoflavone results in decreased expression of SMAD6 mRNA

NCBI chr 9:63,860,358...63,929,374
Ensembl chr 9:63,860,358...63,929,341

G

synuclein, alpha

decreases expression

beta-Naphthoflavone results in decreased expression of SNCA mRNA

NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839

G

SNF related kinase

increases expression

beta-Naphthoflavone results in increased expression of SNRK mRNA

NCBI chr 9:121,946,332...121,998,768
Ensembl chr 9:121,946,332...121,998,768

G

small nuclear ribonucleoprotein polypeptide A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SNRPA mRNA

NCBI chr 7:26,886,431...26,895,696
Ensembl chr 7:26,886,430...26,895,696

G

suppressor of cytokine signaling 2

increases expression

beta-Naphthoflavone results in increased expression of SOCS2 mRNA

NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042

G

superoxide dismutase 2, mitochondrial

increases expression
decreases expression

beta-Naphthoflavone results in increased expression of SOD2 mRNA
beta-Naphthoflavone results in decreased expression of SOD2 mRNA

PMID:32151702 PMID:32858204

NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950

G

sortilin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SORT1 mRNA

NCBI chr 3:108,191,272...108,268,835
Ensembl chr 3:108,191,398...108,268,827

G

sperm associated antigen 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPAG5 mRNA

NCBI chr11:78,192,412...78,213,283
Ensembl chr11:78,192,355...78,213,283

G

sperm associated antigen 8

decreases expression

beta-Naphthoflavone results in decreased expression of SPAG8 mRNA

NCBI chr 4:43,651,330...43,653,594
Ensembl chr 4:43,651,335...43,653,594

G

spindlin 1

increases expression

beta-Naphthoflavone results in increased expression of SPIN1 mRNA

NCBI chr13:51,254,523...51,306,588
Ensembl chr13:51,254,916...51,306,582

G

serine peptidase inhibitor, Kazal type 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SPINK1 mRNA

NCBI chr18:43,861,134...43,870,302
Ensembl chr18:43,861,147...43,870,622

G

spondin 1, (f-spondin) extracellular matrix protein

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SPON1 mRNA

NCBI chr 7:113,365,235...113,642,610
Ensembl chr 7:113,365,235...113,642,605

G

secreted phosphoprotein 1

multiple interactions
decreases expression

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of SPP1 mRNA
beta-Naphthoflavone results in decreased expression of SPP1 mRNA

PMID:19737545 PMID:32858204

NCBI chr 5:104,582,977...104,588,919
Ensembl chr 5:104,582,984...104,588,916

G

small proline-rich protein 2D

increases expression

beta-Naphthoflavone results in increased expression of SPRR2D mRNA

PMID:32151702 PMID:32858204

NCBI chr 3:92,246,447...92,248,187
Ensembl chr 3:92,246,447...92,248,180

G

small proline-rich protein 2E

increases expression

beta-Naphthoflavone results in increased expression of SPRR2E mRNA

NCBI chr 3:92,259,450...92,260,757
Ensembl chr 3:92,259,450...92,260,756

G

small proline-rich protein 2F

increases expression

beta-Naphthoflavone results in increased expression of SPRR2F mRNA

NCBI chr 3:92,272,494...92,273,754
Ensembl chr 3:92,272,494...92,273,749

G

small proline-rich protein 2H

increases expression

beta-Naphthoflavone results in increased expression of SPRR2A mRNA

NCBI chr 3:92,292,992...92,294,631
Ensembl chr 3:92,292,992...92,294,631

G

sprouty RTK signaling antagonist 1

decreases expression

beta-Naphthoflavone results in decreased expression of SPRY1 mRNA

NCBI chr 3:37,694,096...37,698,748
Ensembl chr 3:37,694,096...37,698,747

G

serine palmitoyltransferase, long chain base subunit 3

decreases expression

beta-Naphthoflavone results in decreased expression of SPTLC3 mRNA

NCBI chr 2:139,335,833...139,478,981
Ensembl chr 2:139,335,833...139,479,594

G

squalene epoxidase

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SQLE mRNA
beta-Naphthoflavone results in decreased expression of SQLE mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of SQLE mRNA]

PMID:18164116 PMID:22234961

NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041

G

sequestosome 1

increases expression

beta-Naphthoflavone results in increased expression of SQSTM1 mRNA

NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654

G

Rous sarcoma oncogene

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SRC mRNA

NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782

G

steroid 5 alpha-reductase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SRD5A1 mRNA

NCBI chr13:69,721,568...69,759,611
Ensembl chr13:69,721,568...69,759,561

G

sterol regulatory element binding transcription factor 1

decreases expression

beta-Naphthoflavone results in decreased expression of SREBF1 mRNA

NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407

G

signal recognition particle 19

increases expression

beta-Naphthoflavone results in increased expression of SRP19 mRNA

NCBI chr18:34,464,185...34,469,652
Ensembl chr18:34,463,900...34,469,652

G

signal recognition particle receptor alpha

increases expression

beta-Naphthoflavone results in increased expression of SRPRA mRNA

NCBI chr 9:35,122,499...35,128,299
Ensembl chr 9:35,111,471...35,159,269

G

sushi-repeat-containing protein

decreases expression
increases expression

beta-Naphthoflavone results in decreased expression of SRPX mRNA
beta-Naphthoflavone results in increased expression of SRPX mRNA

PMID:19737606 PMID:32858204

NCBI chr X:9,904,216...9,983,879
Ensembl chr X:9,904,216...9,983,948

G

sulfiredoxin 1 homolog (S. cerevisiae)

multiple interactions
increases expression

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of SRXN1 mRNA
beta-Naphthoflavone results in increased expression of SRXN1 mRNA

PMID:19737545 PMID:32858204

NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296

G

slingshot protein phosphatase 1

increases expression

beta-Naphthoflavone results in increased expression of SSH1 mRNA

NCBI chr 5:114,075,155...114,131,864
Ensembl chr 5:114,075,155...114,131,955

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ST3GAL2 mRNA

NCBI chr 8:111,646,520...111,699,132
Ensembl chr 8:111,646,554...111,699,112

G

ST3 beta-galactoside alpha-2,3-sialyltransferase 6

increases expression

beta-Naphthoflavone results in increased expression of ST3GAL6 mRNA

NCBI chr16:58,290,105...58,344,614
Ensembl chr16:58,288,488...58,344,606

G

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ST6GALNAC2 mRNA

NCBI chr11:116,567,529...116,586,608
Ensembl chr11:116,566,129...116,585,694
Ensembl chr11:116,566,129...116,585,694

G

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

increases expression

beta-Naphthoflavone results in increased expression of ST6GALNAC4 mRNA

NCBI chr 2:32,477,100...32,489,710
Ensembl chr 2:32,477,107...32,489,710

G

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of ST8SIA1 mRNA

NCBI chr 6:142,767,267...142,935,247
Ensembl chr 6:142,767,271...142,910,178

G

StAR related lipid transfer domain containing 6

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of STARD6 mRNA

NCBI chr18:70,605,525...70,638,325
Ensembl chr18:70,605,525...70,634,137

G

signal transducer and activator of transcription 5A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of STAT5A mRNA

NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995

G

STEAP family member 4

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of STEAP4 mRNA

NCBI chr 5:8,010,472...8,032,213
Ensembl chr 5:8,010,457...8,032,213

G

stathmin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of STMN1 mRNA

NCBI chr 4:134,195,631...134,201,154
Ensembl chr 4:134,195,631...134,201,154

G

succinate-CoA ligase, GDP-forming, alpha subunit

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SUCLG1 mRNA

NCBI chr 6:73,225,488...73,253,890
Ensembl chr 6:73,225,365...73,253,894

G

sulfotransferase family, cytosolic, 1C, member 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SULT1C2 mRNA

NCBI chr17:54,136,665...54,152,986
Ensembl chr17:54,136,665...54,153,367

G

sulfotransferase family 1E, member 1

increases expression

beta-Naphthoflavone results in increased expression of SULT1E1 mRNA

NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453

G

sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of SULT2A1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SULT2A1 mRNA

PMID:9566755 PMID:18164116

NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334

G

sulfotransferase family, cytosolic, 2B, member 1

increases expression

beta-Naphthoflavone results in increased expression of SULT2B1 mRNA

NCBI chr 7:45,379,405...45,409,096
Ensembl chr 7:45,379,407...45,434,093

G

sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1

decreases expression

beta-Naphthoflavone results in decreased expression of SVEP1 mRNA

NCBI chr 4:58,042,796...58,206,596
Ensembl chr 4:58,042,442...58,206,859

G

seminal vesicle secretory protein 3B

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of SVS3B mRNA

NCBI chr 2:164,096,283...164,098,563
Ensembl chr 2:164,096,283...164,098,560

G

synapse defective 1, Rho GTPase, homolog 1 (C. elegans)

decreases expression

beta-Naphthoflavone results in decreased expression of SYDE1 mRNA

NCBI chr10:78,420,336...78,427,798
Ensembl chr10:78,420,337...78,427,798

G

synergin, gamma

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of SYNRG mRNA

NCBI chr11:83,855,217...83,935,404
Ensembl chr11:83,855,254...83,935,404

G

synaptotagmin VII

decreases expression

beta-Naphthoflavone results in decreased expression of SYT7 mRNA

NCBI chr19:10,366,142...10,430,545
Ensembl chr19:10,366,454...10,430,544

G

transgelin

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of TAGLN mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TAGLN mRNA

PMID:17175557 PMID:18164116 PMID:32858204

NCBI chr 9:45,840,926...45,847,356
Ensembl chr 9:45,840,917...45,847,356

G

transaldolase 1

increases expression

beta-Naphthoflavone results in increased expression of TALDO1 mRNA

NCBI chr 7:140,972,073...140,982,889
Ensembl chr 7:140,972,112...140,982,881

G

tubulin folding cofactor E-like

increases expression

beta-Naphthoflavone results in increased expression of TBCEL mRNA

NCBI chr 9:42,323,612...42,383,534
Ensembl chr 9:42,323,612...42,419,105

G

thromboxane A synthase 1, platelet

increases expression

beta-Naphthoflavone results in increased expression of TBXAS1 mRNA

NCBI chr 6:38,817,897...39,061,524
Ensembl chr 6:38,852,338...39,061,519

G

transcription factor 19

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TCF19 mRNA

NCBI chr17:35,823,627...35,827,730
Ensembl chr17:35,823,631...35,827,721

G

tryptophan 2,3-dioxygenase

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of TDO2 mRNA

NCBI chr 3:81,865,719...81,883,035
Ensembl chr 3:81,864,397...81,883,509

G

tyrosyl-DNA phosphodiesterase 2

increases expression

beta-Naphthoflavone results in increased expression of TDP2 mRNA

NCBI chr13:25,015,642...25,026,136
Ensembl chr13:25,015,662...25,026,136

G

thyrotroph embryonic factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TEF mRNA

NCBI chr15:81,686,874...81,711,064
Ensembl chr15:81,686,622...81,711,064

G

teneurin transmembrane protein 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TENM2 mRNA

NCBI chr11:35,897,483...37,881,486
Ensembl chr11:35,897,483...37,126,791

G

terminal nucleotidyltransferase 5A

decreases expression

beta-Naphthoflavone results in decreased expression of TENT5A mRNA

NCBI chr 9:85,202,492...85,209,203
Ensembl chr 9:85,202,492...85,209,401

G

transcription factor Dp 2

decreases expression

beta-Naphthoflavone results in decreased expression of TFDP2 mRNA

NCBI chr 9:96,078,348...96,205,699
Ensembl chr 9:96,078,328...96,205,699

G

trefoil factor 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TFF1 mRNA

NCBI chr17:31,380,369...31,384,034
Ensembl chr17:31,380,369...31,384,251

G

tissue factor pathway inhibitor

decreases expression

beta-Naphthoflavone results in decreased expression of TFPI mRNA

NCBI chr 2:84,263,199...84,307,119
Ensembl chr 2:84,263,199...84,307,119

G

transforming growth factor, beta 1

multiple interactions
decreases expression

alpha-naphthoflavone promotes the reaction [beta-Naphthoflavone results in decreased expression of TGFB1 mRNA]

NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502

G

transforming growth factor, beta receptor III

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TGFBR3 mRNA

NCBI chr 5:107,254,433...107,437,495
Ensembl chr 5:107,254,436...107,437,495

G

transglutaminase 1, K polypeptide

affects expression

beta-Naphthoflavone affects the expression of TGM1 protein

NCBI chr14:55,937,466...55,951,378
Ensembl chr14:55,937,466...55,951,383

G

transglutaminase 2, C polypeptide

decreases expression

beta-Naphthoflavone results in decreased expression of TGM2 mRNA

NCBI chr 2:157,958,325...157,988,312
Ensembl chr 2:157,958,322...157,988,356

G

thrombospondin 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of THBS1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THBS1 mRNA

PMID:18164116 PMID:19737545

NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614

G

thyroid hormone responsive

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THRSP mRNA

NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937

G

thymus cell antigen 1, theta

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of THY1 mRNA

NCBI chr 9:43,954,681...43,959,876
Ensembl chr 9:43,954,681...43,959,876

G

tissue inhibitor of metalloproteinase 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TIMP1 mRNA

PMID:18164116 PMID:20045035

NCBI chr X:20,736,524...20,740,972
Ensembl chr X:20,736,405...20,740,974

G

tissue inhibitor of metalloproteinase 2

increases expression

beta-Naphthoflavone results in increased expression of TIMP2 mRNA

NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566

G

TCDD-inducible poly(ADP-ribose) polymerase

increases expression

beta-Naphthoflavone results in increased expression of TIPARP mRNA

PMID:23994337 PMID:32858204

NCBI chr 3:65,435,868...65,462,939
Ensembl chr 3:65,435,831...65,462,939

G

triokinase, FMN cyclase

decreases expression

beta-Naphthoflavone results in decreased expression of TKFC mRNA

NCBI chr19:10,565,153...10,583,257
Ensembl chr19:10,565,155...10,583,018

G

toll-like receptor 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TLR2 mRNA

NCBI chr 3:83,743,579...83,749,045
Ensembl chr 3:83,743,579...83,749,074

G

toll-like receptor 8

increases expression

beta-Naphthoflavone results in increased expression of TLR8 mRNA

NCBI chr X:166,024,119...166,047,325
Ensembl chr X:166,025,692...166,047,325

G

transmembrane 4 superfamily member 1

decreases expression

beta-Naphthoflavone results in decreased expression of TM4SF1 mRNA

NCBI chr 3:57,193,038...57,295,150
Ensembl chr 3:57,193,032...57,209,409
Ensembl chr 3:57,193,032...57,209,409

G

transmembrane 6 superfamily member 2

increases expression

beta-Naphthoflavone results in increased expression of TM6SF2 mRNA

NCBI chr 8:70,525,574...70,532,716
Ensembl chr 8:70,525,574...70,532,716

G

transmembrane p24 trafficking protein 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMED3 mRNA

NCBI chr 9:89,581,256...89,587,096
Ensembl chr 9:89,581,259...89,587,121

G

transmembrane protein 147

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMEM147 mRNA

NCBI chr 7:30,427,126...30,428,959
Ensembl chr 7:30,427,126...30,428,965

G

transmembrane protein 184C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMEM184C mRNA

NCBI chr 8:78,322,607...78,337,343
Ensembl chr 8:78,322,611...78,337,327

G

transmembrane protein 40

increases expression

beta-Naphthoflavone results in increased expression of TMEM40 mRNA

NCBI chr 6:115,706,092...115,739,427
Ensembl chr 6:115,706,092...115,739,371

G

transmembrane protein 70

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TMEM70 protein

PMID:27914986 PMID:28903497

NCBI chr 1:16,735,415...16,748,501
Ensembl chr 1:16,735,431...16,748,499

G

transmembrane protease, serine 11f

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of TMPRSS11F mRNA

NCBI chr 5:86,669,085...86,780,559
Ensembl chr 5:86,669,757...86,780,283

G

thymosin beta 15b2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TMSB15B2 mRNA

NCBI chr X:135,855,737...135,858,728
Ensembl chr X:135,856,014...135,858,774

G

tenascin C

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNC mRNA

NCBI chr 4:63,878,022...63,965,554
Ensembl chr 4:63,878,022...63,965,252

G

tumor necrosis factor

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNF mRNA]
beta-Naphthoflavone results in increased expression of TNF mRNA

PMID:21295105 PMID:32151702

NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983

G

tumor necrosis factor, alpha-induced protein 2

increases expression

beta-Naphthoflavone results in increased expression of TNFAIP2 mRNA

NCBI chr12:111,408,898...111,421,452
Ensembl chr12:111,408,903...111,421,452

G

tumor necrosis factor alpha induced protein 6

decreases expression

beta-Naphthoflavone results in decreased expression of TNFAIP6 mRNA

NCBI chr 2:51,928,125...51,946,693
Ensembl chr 2:51,928,021...51,946,698

G

tumor necrosis factor receptor superfamily, member 12a

multiple interactions
increases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF12A mRNA
beta-Naphthoflavone results in increased expression of TNFRSF12A mRNA

PMID:18164116 PMID:19737606

NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442

G

tumor necrosis factor receptor superfamily, member 19

decreases expression

beta-Naphthoflavone results in decreased expression of TNFRSF19 mRNA

NCBI chr14:61,201,283...61,284,304
Ensembl chr14:61,201,324...61,283,939

G

tumor necrosis factor receptor superfamily, member 1a

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNFRSF1A protein]

NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447

G

tumor necrosis factor receptor superfamily, member 23

decreases expression

beta-Naphthoflavone results in decreased expression of CAPS mRNA

NCBI chr 7:143,219,544...143,239,836
Ensembl chr 7:143,219,546...143,239,609

G

tumor necrosis factor receptor superfamily, member 9

decreases expression

beta-Naphthoflavone results in decreased expression of TNFRSF9 mRNA

NCBI chr 4:151,004,612...151,030,561
Ensembl chr 4:150,999,019...151,030,559

G

troponin C, cardiac/slow skeletal

increases expression
multiple interactions

beta-Naphthoflavone results in increased expression of TNNC1 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TNNC1 mRNA

PMID:18164116 PMID:19737606

NCBI chr14:30,930,274...30,933,671
Ensembl chr14:30,930,269...30,933,686

G

tensin 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TNS4 mRNA

NCBI chr11:98,956,504...98,980,132
Ensembl chr11:98,956,504...98,980,132

G

target of myb1-like 2 (chicken)

decreases expression

beta-Naphthoflavone results in decreased expression of TOM1L2 mRNA

NCBI chr11:60,114,622...60,243,766
Ensembl chr11:60,117,540...60,243,731

G

topoisomerase (DNA) II alpha

multiple interactions
decreases expression

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TOP2A mRNA
beta-Naphthoflavone results in decreased expression of TOP2A mRNA

PMID:18164116 PMID:32858204

NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015

G

torsin family 3, member A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of TOR3A mRNA

NCBI chr 1:156,481,187...156,501,909
Ensembl chr 1:156,481,187...156,501,926

G

tubulin polymerization-promoting protein family member 3

decreases expression

beta-Naphthoflavone results in decreased expression of TPPP3 mRNA

NCBI chr 8:106,194,124...106,198,189
Ensembl chr 8:106,194,125...106,198,158

G

TNFRSF1A-associated via death domain

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein; isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRADD protein]

NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241

G

triggering receptor expressed on myeloid cells-like 2

decreases expression

beta-Naphthoflavone results in decreased expression of TREML2 mRNA

NCBI chr17:48,606,419...48,619,562
Ensembl chr17:48,606,526...48,619,561

G

tribbles pseudokinase 3

increases expression

beta-Naphthoflavone results in increased expression of TRIB3 mRNA

NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952

G

transformation related protein 53

multiple interactions

[beta-Naphthoflavone binds to and results in increased activity of AHR protein] results in decreased susceptibility to [1-nitropyrene results in increased expression of TP53 protein]

NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699

G

transient receptor potential cation channel, subfamily V, member 2

increases expression

beta-Naphthoflavone results in increased expression of TRPV2 mRNA

NCBI chr11:62,465,312...62,491,131
Ensembl chr11:62,465,312...62,491,341

G

transient receptor potential cation channel, subfamily V, member 5

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TRPV5 mRNA

NCBI chr 6:41,628,595...41,658,158
Ensembl chr 6:41,629,107...41,657,703

G

tsukushi, small leucine rich proteoglycan

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TSKU mRNA

NCBI chr 7:97,999,875...98,010,602
Ensembl chr 7:97,999,875...98,010,535

G

tetraspanin 10

decreases expression

beta-Naphthoflavone results in decreased expression of TSPAN10 mRNA

NCBI chr11:120,333,457...120,338,147
Ensembl chr11:120,333,470...120,337,776

G

tetraspanin 7

increases expression

beta-Naphthoflavone results in increased expression of TSPAN7 mRNA

NCBI chr X:10,351,355...10,462,843
Ensembl chr X:10,351,397...10,462,844

G

tetraspanin 8

increases expression

beta-Naphthoflavone results in increased expression of TSPAN8 mRNA

NCBI chr10:115,652,722...115,685,798
Ensembl chr10:115,652,737...115,685,798

G

tetraspanin 9

decreases expression

beta-Naphthoflavone results in decreased expression of TSPAN9 mRNA

NCBI chr 6:127,938,359...128,120,541
Ensembl chr 6:127,938,359...128,120,557

G

tubulin, alpha 1A

decreases expression

beta-Naphthoflavone results in decreased expression of TUBA1A mRNA

NCBI chr15:98,847,728...98,851,382
Ensembl chr15:98,847,718...98,851,584

G

tubulin, beta 5 class I

increases expression

beta-Naphthoflavone results in increased expression of TUBB mRNA

NCBI chr17:36,144,812...36,149,193
Ensembl chr17:36,144,813...36,149,198

G

tubulin, beta 6 class V

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TUBB6 mRNA

NCBI chr18:67,523,801...67,535,819
Ensembl chr18:67,523,787...67,535,819

G

thioredoxin-like 1

increases expression

beta-Naphthoflavone results in increased expression of TXNL1 mRNA

NCBI chr18:63,795,872...63,825,535
Ensembl chr18:63,794,165...63,841,872

G

thioredoxin-like 4A

increases expression

beta-Naphthoflavone results in increased expression of TXNL4A mRNA

NCBI chr18:80,250,041...80,269,066
Ensembl chr18:80,249,980...80,255,956
Ensembl chr18:80,249,980...80,255,956

G

thioredoxin reductase 1

increases expression

beta-Naphthoflavone results in increased expression of TXNRD1 mRNA

PMID:12949356 PMID:19737606 PMID:32858204

NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546

G

thymidylate synthase

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYMS mRNA

NCBI chr 5:30,243,544...30,279,261
Ensembl chr 5:30,263,200...30,278,615

G

TYRO3 protein tyrosine kinase 3

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of TYRO3 mRNA

NCBI chr 2:119,628,123...119,648,585
Ensembl chr 2:119,628,214...119,648,585

G

ubiquitin associated domain containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of UBAC1 mRNA

NCBI chr 2:25,886,970...25,911,793
Ensembl chr 2:25,888,555...25,911,759

G

ubiquitin-associated protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UBAP1 mRNA

NCBI chr 4:41,348,996...41,389,766
Ensembl chr 4:41,348,996...41,390,525

G

ubiquitin C

increases expression

beta-Naphthoflavone results in increased expression of UBC mRNA

NCBI chr 5:125,463,029...125,467,081
Ensembl chr 5:125,463,029...125,467,266

G

ubiquitin D

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UBD mRNA

NCBI chr17:37,504,783...37,506,992
Ensembl chr17:37,504,783...37,506,986

G

ubiquitin-conjugating enzyme E2C

decreases expression

beta-Naphthoflavone results in decreased expression of UBE2C mRNA

NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742

G

ubiquitin-conjugating enzyme E2E 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of UBE2E2 protein

NCBI chr14:3,575,429...3,896,133
Ensembl chr14:3,575,429...3,896,121

G

ubiquitin-conjugating enzyme E2L 3

multiple interactions
increases expression

AHR protein affects the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; UBE2L3 protein affects the reaction [beta-Naphthoflavone results in decreased expression of FOS protein]

NCBI chr16:16,969,879...17,019,363
Ensembl chr16:16,969,877...17,020,513

G

ubiquitin-conjugating enzyme E2Z

increases expression

beta-Naphthoflavone results in increased expression of UBE2Z mRNA

NCBI chr11:95,938,257...95,956,190
Ensembl chr11:95,938,258...95,956,214

G

uridine-cytidine kinase 2

decreases expression

beta-Naphthoflavone results in decreased expression of UCK2 mRNA

NCBI chr 1:167,050,464...167,112,657
Ensembl chr 1:167,050,452...167,112,889

G

UDP-glucose ceramide glucosyltransferase

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of UGCG mRNA
AHR protein affects the reaction [beta-Naphthoflavone results in decreased expression of UGCG mRNA]

NCBI chr 4:59,189,452...59,222,833
Ensembl chr 4:59,189,257...59,222,833

G

UDP-glucose glycoprotein glucosyltransferase 1

decreases expression

beta-Naphthoflavone results in decreased expression of UGGT1 mRNA

NCBI chr 1:36,179,109...36,283,407
Ensembl chr 1:36,179,108...36,283,801

G

UDP glucuronosyltransferase 1 family, polypeptide A1

multiple interactions
increases activity
increases expression

beta-Naphthoflavone promotes the reaction [[AHR protein binds to UGT1A1 enhancer] which results in increased expression of UGT1A1 mRNA]; beta-Naphthoflavone results in increased expression of and results in increased activity of UGT1A1 protein
beta-Naphthoflavone results in increased activity of UGT1A1 protein
beta-Naphthoflavone results in increased expression of UGT1A1 mRNA; beta-Naphthoflavone results in increased expression of UGT1A1 protein

PMID:12566446 PMID:16399344 PMID:17917264 PMID:19118567 PMID:19144771 More...

NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719

G

UDP glycosyltransferase 1 family, polypeptide A10

increases expression

beta-Naphthoflavone results in increased expression of UGT1A10 mRNA

PMID:19118567 PMID:28601433

NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726

G

UDP glucuronosyltransferase 1 family, polypeptide A2

increases expression

beta-Naphthoflavone results in increased expression of UGT1A2 mRNA; beta-Naphthoflavone results in increased expression of UGT1A3 mRNA

PMID:19118567 PMID:28601433

NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719

G

UDP glucuronosyltransferase 1 family, polypeptide A5

increases expression

beta-Naphthoflavone results in increased expression of UGT1A4 mRNA
beta-Naphthoflavone results in increased expression of UGT1A5 mRNA

PMID:19118567 PMID:19144771

NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719

G

UDP glucuronosyltransferase 1 family, polypeptide A6B

multiple interactions
increases expression

beta-Naphthoflavone promotes the reaction [UGT1A6 protein results in increased glucuronidation of 1-naphthol]
beta-Naphthoflavone results in increased expression of UGT1A6 mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA
[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UGT1A6 mRNA

PMID:7646562 PMID:12883083 PMID:12948865 PMID:17917264 PMID:18094037 More...

NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725

G

UDP glucuronosyltransferase 1 family, polypeptide A9

increases expression

beta-Naphthoflavone results in increased expression of UGT1A9 mRNA

PMID:17917264 PMID:19118567 PMID:19144771

NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719

G

UDP glucuronosyltransferase 2 family, polypeptide A3

decreases expression

beta-Naphthoflavone results in decreased expression of UGT2A3 mRNA

NCBI chr 5:87,472,694...87,485,054
Ensembl chr 5:87,472,831...87,485,054

G

UDP glucuronosyltransferase 2 family, polypeptide B35

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT2B35 mRNA

NCBI chr 5:87,148,719...87,161,133
Ensembl chr 5:87,148,719...87,161,134

G

UDP glucuronosyltransferase 2 family, polypeptide B5

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in increased expression of UGT2B5 mRNA

NCBI chr 5:87,272,805...87,288,199
Ensembl chr 5:87,272,819...87,288,177

G

unkempt family like zinc finger

increases expression

beta-Naphthoflavone results in increased expression of UNKL mRNA

NCBI chr17:25,407,336...25,453,417
Ensembl chr17:25,407,371...25,453,417

G

UTP25 small subunit processome component

increases expression

beta-Naphthoflavone results in increased expression of UTP25 mRNA

NCBI chr 1:192,786,707...192,812,603
Ensembl chr 1:192,773,412...192,812,580

G

utrophin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of UTRN mRNA

NCBI chr10:12,257,931...12,745,632
Ensembl chr10:12,257,932...12,745,109

G

UV radiation resistance associated gene

increases expression

beta-Naphthoflavone results in increased expression of UVRAG mRNA

NCBI chr 7:98,535,949...98,790,373
Ensembl chr 7:98,534,228...98,790,348

G

vascular cell adhesion molecule 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VCAM1 mRNA

NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337

G

ventricular zone expressed PH domain-containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VEPH1 mRNA

NCBI chr 3:65,960,979...66,204,370
Ensembl chr 3:65,960,979...66,204,258

G

villin 1

multiple interactions

[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VIL1 mRNA

NCBI chr 1:74,448,543...74,474,719
Ensembl chr 1:74,448,535...74,474,718

G

vimentin

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VIM mRNA
[andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of VIM mRNA

PMID:18164116 PMID:19737545

NCBI chr 2:13,579,122...13,587,637
Ensembl chr 2:13,578,738...13,587,637

G

vanin 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VNN1 mRNA

NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241

G

Von Willebrand factor

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of VWF mRNA

NCBI chr 6:125,529,911...125,663,642
Ensembl chr 6:125,523,737...125,663,642

G

whey acidic protein

decreases expression
multiple interactions

beta-Naphthoflavone results in decreased expression of WAP mRNA
AHR gene alternative form affects the reaction [beta-Naphthoflavone results in decreased expression of WAP mRNA]; beta-Naphthoflavone inhibits the reaction [[PRL protein co-treated with Dexamethasone] results in increased expression of WAP mRNA]

NCBI chr11:6,585,483...6,588,654
Ensembl chr11:6,585,482...6,588,637

G

WD repeat domain 45

increases expression

beta-Naphthoflavone results in increased expression of WDR45 mRNA

NCBI chr X:7,588,212...7,594,439
Ensembl chr X:7,580,572...7,594,445

G

wolframin ER transmembrane glycoprotein

decreases expression

beta-Naphthoflavone results in decreased expression of WFS1 mRNA

NCBI chr 5:37,123,448...37,146,326
Ensembl chr 5:37,123,448...37,146,549

G

WNK lysine deficient protein kinase 4

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of WNK4 mRNA

NCBI chr11:101,151,363...101,168,235
Ensembl chr11:101,151,393...101,168,235

G

wingless-type MMTV integration site family, member 2B

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of WNT2B mRNA

NCBI chr 3:104,852,121...104,869,025
Ensembl chr 3:104,852,588...104,869,237

G

wingless-type MMTV integration site family, member 5A

increases expression

beta-Naphthoflavone results in increased expression of WNT5A mRNA

NCBI chr14:28,224,962...28,249,405
Ensembl chr14:28,226,707...28,249,405

G

WD repeat and SOCS box-containing 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of WSB1 mRNA

NCBI chr11:79,130,208...79,145,521
Ensembl chr11:79,130,198...79,145,497

G

X-box binding protein 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of XBP1 mRNA

NCBI chr11:5,470,641...5,475,993
Ensembl chr11:5,470,659...5,475,893

G

xanthine dehydrogenase

increases expression

beta-Naphthoflavone results in increased expression of XDH mRNA

NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191

G

X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of XPNPEP2 mRNA

NCBI chr X:47,195,790...47,225,859
Ensembl chr X:47,197,602...47,225,858

G

yippee like 1

increases expression

beta-Naphthoflavone results in increased expression of YPEL1 mRNA

NCBI chr16:16,887,454...16,904,912
Ensembl chr16:16,887,560...16,904,909

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide

increases expression

beta-Naphthoflavone results in increased expression of YWHAE mRNA

NCBI chr11:75,620,121...75,656,667
Ensembl chr11:75,623,695...75,656,671

G

zinc finger and BTB domain containing 16

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZBTB16 mRNA

NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522

G

zinc finger CCCH type, antiviral 1

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZC3HAV1 mRNA

NCBI chr 6:38,282,221...38,332,859
Ensembl chr 6:38,282,221...38,331,538

G

zinc finger, DHHC domain containing 2

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZDHHC2 mRNA

NCBI chr 8:40,876,526...40,946,178
Ensembl chr 8:40,876,856...40,963,309

G

zinc finger protein 219

affects expression

beta-Naphthoflavone affects the expression of ZFP219 mRNA

NCBI chr14:52,243,532...52,258,597
Ensembl chr14:52,243,534...52,258,190

G

zinc finger protein 354A

multiple interactions

[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ZNF354A mRNA

NCBI chr11:50,950,052...50,963,626
Ensembl chr11:50,950,084...50,963,626

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	22205
role	22190
biological role	22189
pharmacological role	19801
agonist	19253
aryl hydrocarbon receptor agonist	2044
beta-naphthoflavone	1127
Path 2
Term	Annotations
CHEBI ontology	22205
subatomic particle	22197
composite particle	22197
hadron	22197
baryon	22197
nucleon	22169
atomic nucleus	22197
atom	22197
main group element atom	22131
p-block element atom	22131
carbon group element atom	21928
carbon atom	21854
organic molecular entity	21854
organic molecule	21671
organic cyclic compound	21276
organic heterocyclic compound	20346
oxacycle	18876
benzopyran	12219
1-benzopyran	11978
flavonoid	7275
extended flavonoid	1223
beta-naphthoflavone	1127

paths to the root