Ubc (ubiquitin C) - Rat Genome Database

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General
Array IDs

Gene: Ubc (ubiquitin C) Mus musculus

Symbol:

Ubc

Name:

ubiquitin C

Description:

ENCODES a protein that exhibits protease binding (ortholog); INVOLVED IN ubiquitin homeostasis; ASSOCIATED WITH abnormal cell cycle; abnormal cell death; abnormal embryonic hematopoiesis; FOUND IN cytoplasm (inferred); nucleus (inferred); INTERACTS WITH (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 17alpha-ethynylestradiol

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

2700054O04Rik; AI194771; OTTMUSP00000046440; OTTMUSP00000046454; OTTMUSP00000046455; polyubiquitin C; polyubiquitin-C; Rps27a; TI-225; Uba52; Ubb; ubiquitin

Orthologs:

Homo sapiens : UBC (ubiquitin C) HGNC
Rattus norvegicus : Ubc (ubiquitin C)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	5	125,385,965 - 125,390,017	-	NCBI
Mouse cM Map	5	64.18		NCBI
Mouse Celera Assembly	5	122,405,521 - 122,411,999	-	NCBI
Mouse Genome Assembly Build 37	5	125,866,335 - 125,870,387	-	NCBI
Mouse Genome Assembly Build 36.1	5	125,866,347 - 125,870,100	-	NCBI
Mouse Cytogenetic Map	5	G1.1		NCBI

Model

Launch Genome Browser (GBrowse)

Annotation (Toggle Detail/Summary View)

Gene-Chemical Interaction Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
(S)-nicotine	multiple interactions	EXP		6480464	[Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of UBC mRNA; more ...	CTD	PMID:20230807
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	decreases expression	EXP		6480464	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of UBC mRNA	CTD	PMID:20230807
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine	multiple interactions	EXP		6480464	[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of UBC mRNA; more ...	CTD	PMID:20230807
17alpha-ethynylestradiol	increases expression	EXP		6480464	Ethinyl Estradiol results in increased expression of UBC mRNA	CTD	PMID:17942748 PMID:17555576
17alpha-ethynylestradiol	increases expression	EXP		6480464	Ethinyl Estradiol results in increased expression of UBC mRNA	CTD	PMID:17555576 PMID:17942748
17alpha-ethynylestradiol	multiple interactions	EXP		6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBC mRNA	CTD	PMID:17942748
17beta-estradiol	increases expression	ISO	RGD:1346853	6480464	Estradiol results in increased expression of UBC mRNA	CTD	PMID:20106945
2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:621244	6480464	Tetrachlorodibenzodioxin results in increased expression of UBC mRNA	CTD	PMID:16466705 PMID:18465118
2,3,7,8-tetrachlorodibenzodioxine	increases expression	ISO	RGD:621244	6480464	Tetrachlorodibenzodioxin results in increased expression of UBC mRNA	CTD	PMID:18465118 PMID:16466705
2,3,7,8-tetrachlorodibenzodioxine	multiple interactions	EXP		6480464	[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UBC mRNA	CTD	PMID:17942748
2-butoxyethanol	increases expression	EXP		6480464	n-butoxyethanol results in increased expression of UBC mRNA	CTD	PMID:19812364
2-methylcholine	affects expression	ISO	RGD:1346853	6480464	beta-methylcholine affects the expression of UBC mRNA	CTD	PMID:21179406
4,4'-diaminodiphenylmethane	decreases expression	EXP		6480464	4,4'-diaminodiphenylmethane results in decreased expression of UBC mRNA	CTD	PMID:18648102
alpha-hexachlorocyclohexane	increases expression	ISO	RGD:621244	6480464	alpha-hexachlorocyclohexane results in increased expression of UBC mRNA	CTD	PMID:16940010
ammonium chloride	affects expression	ISO	RGD:621244	6480464	Ammonium Chloride affects the expression of UBC mRNA	CTD	PMID:16483693
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:20127859
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:19770486 more ...
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:19770486 more ...
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:19770486 more ...
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:20127859 more ...
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:21569818 more ...
benzo[a]pyrene	increases expression	EXP		6480464	Benzo(a)pyrene results in increased expression of UBC mRNA	CTD	PMID:19770486 PMID:20127859
benzo[a]pyrene	multiple interactions	EXP		6480464	[Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of UBC mRNA	CTD	PMID:21715664
cadmium dichloride	multiple interactions	EXP		6480464	[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA	CTD	PMID:19840844
cadmium dichloride	increases expression	ISO	RGD:621244	6480464	Cadmium Chloride results in increased expression of UBC mRNA	CTD	PMID:19010381
cadmium sulfate	increases expression	ISO	RGD:1346853	6480464	cadmium sulfate results in increased expression of UBC mRNA	CTD	PMID:21783983
cadmium sulfate	multiple interactions	EXP		6480464	cadmium sulfate affects the reaction [MTF1 affects the expression of UBC mRNA]	CTD	PMID:16221973
caffeine	multiple interactions	EXP		6480464	[Caffeine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of UBC mRNA; more ...	CTD	PMID:20230807
chloroquine	increases expression	ISO	RGD:621244	6480464	Chloroquine results in increased expression of UBC mRNA	CTD	PMID:19296457
chlorpyrifos	increases expression	ISO	RGD:621244	6480464	Chlorpyrifos results in increased expression of UBC mRNA	CTD	PMID:18668222
ciguatoxin CTX1B	affects expression	EXP		6480464	Ciguatoxins affects the expression of UBC mRNA	CTD	PMID:18353800
clofibrate	decreases expression	EXP		6480464	Clofibrate results in decreased expression of UBC mRNA	CTD	PMID:17585979
clofibrate	multiple interactions	EXP		6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of UBC mRNA; more ...	CTD	PMID:17585979
cobalt dichloride	increases expression	ISO	RGD:1346853	6480464	cobaltous chloride results in increased expression of UBC mRNA	CTD	PMID:19320972 PMID:19376846
cobalt dichloride	increases expression	ISO	RGD:1346853	6480464	cobaltous chloride results in increased expression of UBC mRNA	CTD	PMID:17553155 more ...
copper(2+) sulfate	increases expression	ISO	RGD:1346853	6480464	Copper Sulfate results in increased expression of UBC mRNA	CTD	PMID:19549813
copper(II) chloride	increases expression	ISO	RGD:1346853	6480464	cupric chloride results in increased expression of UBC mRNA	CTD	PMID:17211630
curcumin	increases expression	ISO	RGD:1346853	6480464	Curcumin results in increased expression of UBC mRNA	CTD	PMID:16101141
cyclosporin A	increases expression	ISO	RGD:1346853	6480464	Cyclosporine results in increased expression of UBC mRNA	CTD	PMID:20106945
Delta(9)-tetrahydrocannabinol	decreases expression	ISO	RGD:621244	6480464	Tetrahydrocannabinol results in decreased expression of UBC mRNA	CTD	PMID:11015613
dexamethasone	increases expression	EXP		6480464	Dexamethasone results in increased expression of UBC mRNA	CTD	PMID:21041162
diarsenic trioxide	decreases expression	ISO	RGD:1346853	6480464	arsenic trioxide results in decreased expression of UBC protein	CTD	PMID:19364129
diazoxide	decreases expression	EXP		6480464	Isoproterenol results in decreased expression of UBC mRNA	CTD	PMID:20003209
dibutyl phthalate	decreases expression	ISO	RGD:621244	6480464	Dibutyl Phthalate results in decreased expression of UBC mRNA	CTD	PMID:17379624
diethylstilbestrol	increases expression	EXP		6480464	Diethylstilbestrol results in increased expression of UBC mRNA	CTD	PMID:21041162
doxorubicin	increases expression	EXP		6480464	Doxorubicin results in increased expression of UBC mRNA	CTD	PMID:22016648
isoprenaline	decreases expression	EXP		6480464	Isoproterenol results in decreased expression of UBC mRNA	CTD	PMID:20003209
lead diacetate	decreases expression	EXP		6480464	lead acetate results in decreased expression of UBC mRNA	CTD	PMID:21829687
maneb	multiple interactions	EXP		6480464	[Paraquat co-treated with Maneb] results in increased expression of UBC mRNA	CTD	PMID:18386188
menadione	affects expression	ISO	RGD:1346853	6480464	Vitamin K 3 affects the expression of UBC mRNA	CTD	PMID:20044591
N-methyl-N'-nitro-N-nitrosoguanidine	multiple interactions	EXP		6480464	[Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in decreased expression of UBC mRNA; more ...	CTD	PMID:19840844
N-nitrosodiethylamine	increases expression	EXP		6480464	Diethylnitrosamine results in increased expression of UBC mRNA	CTD	PMID:17942915
N-nitrosodiethylamine	multiple interactions	EXP		6480464	MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UBC mRNA]	CTD	PMID:17942915
nitric oxide	increases expression	EXP		6480464	Nitric Oxide deficiency results in increased expression of UBC mRNA	CTD	PMID:15878706
okadaic acid	multiple interactions	EXP		6480464	[Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in decreased expression of UBC mRNA	CTD	PMID:19840844
paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of UBC protein	CTD	PMID:21329376
paracetamol	multiple interactions	EXP		6480464	[Clofibrate co-treated with Acetaminophen] affects the expression of UBC mRNA; more ...	CTD	PMID:17585979
paracetamol	affects expression	EXP		6480464	Acetaminophen affects the expression of UBC mRNA	CTD	PMID:15606129
paracetamol	increases expression	EXP		6480464	Acetaminophen results in increased expression of UBC mRNA	CTD	PMID:11264010
paraquat	increases expression	EXP		6480464	Paraquat results in increased expression of UBC mRNA	CTD	PMID:12595580
paraquat	multiple interactions	EXP		6480464	[Paraquat co-treated with Maneb] results in increased expression of UBC mRNA	CTD	PMID:18386188
phenobarbital	affects expression	EXP		6480464	Phenobarbital affects the expression of UBC mRNA	CTD	PMID:23091169
phlorizin	decreases expression	EXP		6480464	Phlorhizin results in decreased expression of UBC mRNA	CTD	PMID:22538082
phorbol 13-acetate 12-myristate	multiple interactions	EXP		6480464	[Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of UBC mRNA	CTD	PMID:19840844
pyrogallol	increases expression	EXP		6480464	Pyrogallol results in increased expression of UBC mRNA	CTD	PMID:20362636
quercetin	decreases expression	EXP		6480464	Quercetin results in decreased expression of UBC mRNA	CTD	PMID:19496084
S-butyl-DL-homocysteine (S,R)-sulfoximine	increases expression	EXP		6480464	Buthionine Sulfoximine results in increased expression of UBC mRNA	CTD	PMID:15878706
silicon dioxide	increases expression	EXP		6480464	Silicon Dioxide results in increased expression of UBC mRNA	CTD	PMID:19073995
sodium dichromate	increases expression	ISO	RGD:1346853	6480464	sodium bichromate results in increased expression of UBC mRNA	CTD	PMID:12760830
sulfasalazine	increases expression	EXP		6480464	Sulfasalazine results in increased expression of UBC mRNA	CTD	PMID:22016648
tamoxifen	affects expression	EXP		6480464	Tamoxifen affects the expression of UBC mRNA	CTD	PMID:17555576 PMID:20937368
tamoxifen	affects expression	EXP		6480464	Tamoxifen affects the expression of UBC mRNA	CTD	PMID:20937368 PMID:17555576
tetrachloromethane	affects expression	ISO	RGD:621244	6480464	Carbon Tetrachloride affects the expression of UBC mRNA	CTD	PMID:15963342
toluene	affects expression	ISO	RGD:621244	6480464	Toluene affects the expression of UBC mRNA	CTD	PMID:21827849
valproic acid	affects expression	EXP		6480464	Valproic Acid affects the expression of UBC mRNA	CTD	PMID:17292431
zinc atom	multiple interactions	ISO	RGD:1346853	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of UBC mRNA	CTD	PMID:18593933
zinc(0)	multiple interactions	ISO	RGD:1346853	6480464	[PCI 5002 co-treated with Zinc] results in increased expression of UBC mRNA	CTD	PMID:18593933

Gene Ontology Annotations

Biological Process

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
ubiquitin homeostasis		IGI	MGI:MGI:98888	2290270	MGI:MGI:5310665\|PMID:22285186	MGI	MGI:MGI:5310665 PMID:22285186

Cellular Component

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
cytoplasm		IEA	UniProtKB-KW:KW-0963	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194
nucleus		IEA	UniProtKB-KW:KW-0539	2290270	MGI:MGI:1354194	UniProtKB	MGI:MGI:1354194

Molecular Function

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
protease binding		ISO	UniProtKB:P0CG48	2290270	MGI:MGI:4834177	MGI	MGI:MGI:4834177

Molecular Pathway Annotations

External Database Links
KEGG Pathway	PPAR signaling pathway

Phenotype Annotations

Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
abnormal cell cycle		IAGP		5509061		MGI	PMID:17491588
abnormal cell death		IAGP		5509061		MGI	PMID:17491588
abnormal embryonic hematopoiesis		IAGP		5509061		MGI	PMID:17491588
abnormal liver development		IAGP		5509061		MGI	PMID:17491588
complete lethality throughout fetal growth and development		IAGP		5509061		MGI	PMID:17491588
complete perinatal lethality		IAGP		5509061		MGI	PMID:17491588
decreased cell proliferation		IAGP		5509061		MGI	PMID:17491588
decreased embryo size		IAGP		5509061		MGI	PMID:17491588
early cellular replicative senescence		IAGP		5509061		MGI	PMID:17491588
partial embryonic lethality during organogenesis		IAGP		5509061		MGI	PMID:17491588

Gene-Chemical Interaction Annotations

	(S)-nicotine (EXP)
	1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (EXP)
	17alpha-ethynylestradiol (EXP)
	17beta-estradiol (ISO)
	2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)
	2-butoxyethanol (EXP)
	2-methylcholine (ISO)
	4,4'-diaminodiphenylmethane (EXP)
	alpha-hexachlorocyclohexane (ISO)
	ammonium chloride (ISO)
	benzo[a]pyrene (EXP)
	cadmium dichloride (EXP,ISO)
	cadmium sulfate (EXP,ISO)
	caffeine (EXP)
	chloroquine (ISO)
	chlorpyrifos (ISO)
	ciguatoxin CTX1B (EXP)
	clofibrate (EXP)
	cobalt dichloride (ISO)

	copper(2+) sulfate (ISO)
	copper(II) chloride (ISO)
	curcumin (ISO)
	cyclosporin A (ISO)
	Delta(9)-tetrahydrocannabinol (ISO)
	dexamethasone (EXP)
	diarsenic trioxide (ISO)
	diazoxide (EXP)
	dibutyl phthalate (ISO)
	diethylstilbestrol (EXP)
	doxorubicin (EXP)
	isoprenaline (EXP)
	lead diacetate (EXP)
	maneb (EXP)
	menadione (ISO)
	N-methyl-N'-nitro-N-nitrosoguanidine (EXP)
	N-nitrosodiethylamine (EXP)
	nitric oxide (EXP)
	okadaic acid (EXP)

	paracetamol (EXP)
	paraquat (EXP)
	phenobarbital (EXP)
	phlorizin (EXP)
	phorbol 13-acetate 12-myristate (EXP)
	pyrogallol (EXP)
	quercetin (EXP)
	S-butyl-DL-homocysteine (S,R)-sulfoximine (EXP)
	silicon dioxide (EXP)
	sodium dichromate (ISO)
	sulfasalazine (EXP)
	tamoxifen (EXP)
	tetrachloromethane (ISO)
	toluene (ISO)
	valproic acid (EXP)
	zinc atom (ISO)
	zinc(0) (ISO)

Gene Ontology Annotations

Biological Process

ubiquitin homeostasis (IGI)

Cellular Component

cytoplasm (IEA)

nucleus (IEA)

Molecular Function

protease binding (ISO)

Molecular Pathway Annotations

External Database Links
KEGG Pathway	PPAR signaling pathway

Phenotype Annotations

	abnormal cell cycle (IAGP)
	abnormal cell death (IAGP)
	abnormal embryonic hematopoiesis (IAGP)
	abnormal liver development (IAGP)

	complete lethality throughout fetal growth and development (IAGP)
	complete perinatal lethality (IAGP)
	decreased cell proliferation (IAGP)
	decreased embryo size (IAGP)

	early cellular replicative senescence (IAGP)
	partial embryonic lethality during organogenesis (IAGP)

References - curated

1.	RGD automated import pipeline
2.	RGD automated import pipeline for gene-chemical interactions

References - uncurated

PubMed	10097128
	10347229
	10349636
	10438476
	10673385
	10722677
	10748014
	10921894
	10922068
	10940298
	11042159
	11076861
	11217851
	11226337
	11274764
	11435423
	11456111
	11544199
	11964285
	12107596
	12193575
	12231209
	12411482
	12439624
	12466851
	12477932
	12691733
	12697763
	12738770
	12913066
	12960162
	1315303
	1321656
	14522994
	14607830
	14610273
	14704188
	14711818
	14960280
	15001553
	15033975
	15222982
	15297464
	15361067
	15379887
	15467733
	15528042
	15531760
	15537391
	15664989
	15753096
	15782199
	15820682
	15836773
	15837792
	15878855
	15899874
	15964796
	16079148
	16103111
	16113645
	16134970
	16141072
	16141073
	16163708
	16252010
	16371654
	16378096
	16387660
	16461359
	16469705
	16501569
	16537649
	16569768
	16625151
	16704373
	16713561
	16810319
	16908410
	16959774
	16959829
	16973439
	16987252
	17003038
	17015433
	17053834
	17057714
	17086174
	17095659
	17114420
	17139251
	17174123
	17182860
	17189251
	17189825
	17215516
	17242355
	17242400
	17317785
	17341133
	17420218
	17491588
	17493844
	17562858
	17591699
	17604020
	17618294
	17620338
	17653084
	17662948
	17698038
	17703191
	17786239
	17823119
	17904548
	17936707
	17942533
	17947236
	17954934
	17967898
	17981138
	18031698
	18041763
	18162470
	18174161
	18178578
	18198176
	18199748
	18201976
	18206965
	18246070
	18254724
	18268035
	18286479
	18378670
	18382763
	18497817
	18512965
	18562292
	18562480
	18566590
	18567580
	18621737
	18656624
	18708583
	18729080
	18782602
	18786927
	18799693
	18814181
	18821706
	18824541
	18842586
	18931663
	18931680
	18981217
	19036738
	19088199
	19136968
	19148122
	19229105
	19230833
	19240121
	19263517
	19270718
	19279002
	19296467
	19332566
	19366690
	19372219
	19419964
	19427866
	19473982
	19483718
	19546233
	19584057
	19591226
	19602042
	19604354
	19631210
	19651900
	19660437
	19703557
	19725872
	19734451
	19734906
	19754430
	19786557
	19830703
	19880496
	19880522
	19898466
	19898473
	19966925
	19995909
	20008554
	20023214
	20037154
	20058232
	20064468
	20103837
	20159449
	20173742
	20185725
	20206555
	20307651
	20308550
	20352047
	20375183
	20392800
	20463034
	20516642
	20588253
	20631012
	20668528
	20697359
	20805681
	20844536
	20855896
	20864537
	20889505
	20929865
	21029865
	21041311
	21044682
	21151134
	21170031
	21186355
	21245377
	21262463
	21359963
	21368834
	21435586
	21460221
	21478324
	21520210
	21543763
	21565394
	21566132
	21574998
	21576355
	21600962
	21610068
	21637952
	21690297
	21703539
	21723927
	21725320
	21730132
	21757726
	21762413
	21764741
	21765415
	21817095
	21820362
	21829535
	21849678
	21883213
	21955513
	21966515
	22001906
	22037414
	22045334
	22079573
	22081111
	22094330
	22212051
	22216266
	22285186
	22294748
	22337885
	22364282
	22393459
	22411628
	22451666
	22460798
	22473005
	22508726
	22514278
	22593578
	22693634
	22707723
	22713603
	22734001
	22754359
	22761574
	22792322
	22798426
	22801410
	22878500
	22884776
	22949615
	22952242
	22964642
	22976837
	22984419
	23028697
	23060438
	7512619
	7527401
	8631027
	8889548
	9233789
	9321482
	9500786
	9504932
	9551090
	9732264
	9811942
	9826531

Genomics

Comparative Map Data

Ubc (Mus musculus)

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	5	125,385,965 - 125,390,017	-	NCBI
Mouse cM Map	5	64.18		NCBI
Mouse Celera Assembly	5	122,405,521 - 122,411,999	-	NCBI
Mouse Genome Assembly Build 37	5	125,866,335 - 125,870,387	-	NCBI
Mouse Genome Assembly Build 36.1	5	125,866,347 - 125,870,100	-	NCBI
Mouse Cytogenetic Map	5	G1.1		NCBI

UBC (Homo sapiens)

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	12	125,211,366 - 125,214,761	-	NCBI
Human Genome Assembly HuRef	12	122,358,235 - 122,361,174	-	NCBI
Human Genome Assembly GRCh37	12	125,396,192 - 125,399,587	-	NCBI
Human Genome Assembly Build 36	12	123,962,145 - 123,965,530	-	NCBI
Human Cytogenetic Map	12	q24.3		NCBI
Human Genome Assembly	12	123,921,073 - 123,924,077		NCBI

Ubc (Rattus norvegicus)

Map	Chr	Position	Strand	Source
Rat Cytogenetic Map	12	q14		NCBI
RGSC Genome Assembly v5.0	12	38,515,328 - 38,520,061	+	NCBI
RGSC Genome Assembly v3.4	12	32,333,211 - 32,337,944	+	NCBI
Rat Celera Assembly	12	32,933,657 - 32,936,338	+	NCBI
Genome Assembly 3.1	12	32,196,598 - 32,201,332	+	NCBI

Position Markers

AI194771

Map	Chr	Position	Source
Mouse Whitehead/MRC_RH	5	1521.26	UniSTS
Mouse Celera Assembly	5	122,405,610 - 122,405,972	UniSTS
Mouse Celera Assembly	5	122,405,610 - 122,405,744	UniSTS
Mouse Genome Assembly Build 37	5	125,866,424 - 125,866,786	UniSTS
Mouse Genome Assembly Build 37	5	125,866,424 - 125,866,558	UniSTS
Mouse Cytogenetic Map	5	G1.1	UniSTS

Ubc

Map	Chr	Position	Source
Mouse cM Map	5	64.18	UniSTS
Mouse Cytogenetic Map	5	G1.1	UniSTS
Mouse Cytogenetic Map	14	C1	UniSTS
Mouse Cytogenetic Map	11	B2	UniSTS

QTLs in Region (Mouse Genome Assembly Build 37)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4142064	Tmc1m4_m	Tmc1 modifier 4 (mouse)			Not determined		5	54734074	127404378	Mouse
4141993	Dbmc2_m	diabetes mRNA cluster 2 (mouse)			Not determined		5	92519777	126519926	Mouse
1301974	Chab7_m	cholesterol absorption 7 (mouse)			Not determined		5	95514368	129514484	Mouse
1357644	Egrd1_m	early growth rate, direct effect 1 (mouse)			Not determined		5	95715734	129715940	Mouse
1357451	Nrtim1_m	neurotensin immunoreactivity 1 (mouse)			Not determined		5	95746703	129746876	Mouse
1300940	Actd3_m	activity-distance traveled 3 (mouse)			Not determined		5	96601539	130601687	Mouse
1357707	Elpfm_m	eye lens protein fluorescence emission (mouse)			Not determined		5	97333701	131333934	Mouse
4142123	Vmmt7_m	vertebral morphology and mechanical traits 7 (mouse)			Not determined		5	97333701	131333934	Mouse
1301858	Smdq1_m	segregation of mitochondrial DNA QTL 1 (mouse)			Not determined		5	97333701	131333934	Mouse
1300659	Pcd8ts1_m	p-glycoprotein positive CD8 T cell subset 1 (mouse)			Not determined		5	97333701	131333934	Mouse
1357886	Diht_m	dopamine-induced hypothermia (mouse)			Not determined		5	98413178	132413490	Mouse
1301624	Aevm2_m	autoimmune extremity vasculitis in MRL mice 2 (mouse)			Not determined		5	102175776	136175972	Mouse
1301226	Bbaa2_m	B.burgdorferi-associated arthritis 2 (mouse)			Not determined		5	103256981	137257096	Mouse
4142275	Secia2_m	small effect CIA locus 2 (mouse)			Not determined		5	103330450	137330573	Mouse
1301362	Prnr1_m	prion resistance 1 (mouse)			Not determined		5	108309605	142309718	Mouse
4142305	Find2_m	fat induced diabetes 2 (mouse)			Not determined		5	108309605	142309718	Mouse
1558774	Lith17_m	lithogenic gene 17 (mouse)			Not determined		5	108309605	142309718	Mouse
4142473	Chlq11_m	circulating hormone level QTL 11 (mouse)			Not determined		5	108309605	142309718	Mouse
1357815	Fmgty4_m	femur geometry 4 (mouse)			Not determined		5	108309605	142309718	Mouse
1558837	Marq1_m	methamphetamine response QTL 1 (mouse)			Not determined		5	108309605	142309718	Mouse
1300913	Bwefm_m	body weight females and males day 10 (mouse)			Not determined		5	109842654	143842765	Mouse
1301763	Hdlq1_m	HDL QTL 1 (mouse)			Not determined		5	110266961	144267081	Mouse
1300617	Naq1_m	nurturing ability QTL 1 (mouse)			Not determined		5	110404260	144404378	Mouse
1301543	Hypch_m	hypercholesterolemia (mouse)			Not determined		5	111949554	145949692	Mouse
1300694	Tmevd7_m	Theiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 7 (mouse)			Not determined		5	113061274	147061417	Mouse
1301281	Frp2_m	free running period 2 (mouse)			Not determined		5	113061274	147061417	Mouse
1302175	Dssc1_m	dextran sodium sulfate induced colitis QTL1 (mouse)			Not determined		5	115580851	149580964	Mouse
4141408	Wght4_m	weight 4 (mouse)			Not determined		5	115603109	149603232	Mouse
1300827	Cora1_m	correlation in cytokine production 1 (mouse)			Not determined		5	115603914	149604046	Mouse
1301857	Bglq14_m	body growth late QTL 14 (mouse)			Not determined		5	119395980	152453783	Mouse
1301986	Bpq4_m	blood pressure QTL 4 (mouse)			Not determined		5	121998202	152453783	Mouse
1301715	Elmaz2_m	elevated maze behavior 2 (mouse)			Not determined		5	122266536	152453783	Mouse
1302079	Lbw3_m	lupus NZB x NZW 3 (mouse)			Not determined		5	125190534	152453783	Mouse
1301363	Pbwg13_m	postnatal body weight growth 13 (mouse)			Not determined		5	125623656	152453783	Mouse

Sequence

Nucleotide Sequences

Nucleotide RefSeqs	NM_019639	(Get FASTA)	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHY01049250	(Get FASTA)	Search GEO for Microarray Profiles
	AAHY01049251	(Get FASTA)	Search GEO for Microarray Profiles
	AC138613	(Get FASTA)	Search GEO for Microarray Profiles
	AF285161	(Get FASTA)	Search GEO for Microarray Profiles
	AF285162	(Get FASTA)	Search GEO for Microarray Profiles
	AI839133	(Get FASTA)	Search GEO for Microarray Profiles
	AK004727	(Get FASTA)	Search GEO for Microarray Profiles
	AK010964	(Get FASTA)	Search GEO for Microarray Profiles
	AK012427	(Get FASTA)	Search GEO for Microarray Profiles
	AK168448	(Get FASTA)	Search GEO for Microarray Profiles
	AK181246	(Get FASTA)	Search GEO for Microarray Profiles
	AK182022	(Get FASTA)	Search GEO for Microarray Profiles
	AK187354	(Get FASTA)	Search GEO for Microarray Profiles
	AK187639	(Get FASTA)	Search GEO for Microarray Profiles
	AK212399	(Get FASTA)	Search GEO for Microarray Profiles
	BC006680	(Get FASTA)	Search GEO for Microarray Profiles
	BC008661	(Get FASTA)	Search GEO for Microarray Profiles
	BC021837	(Get FASTA)	Search GEO for Microarray Profiles
	BC025894	(Get FASTA)	Search GEO for Microarray Profiles
	BC036303	(Get FASTA)	Search GEO for Microarray Profiles
	BC094012	(Get FASTA)	Search GEO for Microarray Profiles
	CF162845	(Get FASTA)	Search GEO for Microarray Profiles
	CF172065	(Get FASTA)	Search GEO for Microarray Profiles
	CH466529	(Get FASTA)	Search GEO for Microarray Profiles
	CO044895	(Get FASTA)	Search GEO for Microarray Profiles
	D50527	(Get FASTA)	Search GEO for Microarray Profiles
	DV649363	(Get FASTA)	Search GEO for Microarray Profiles
	EF580991	(Get FASTA)	Search GEO for Microarray Profiles
	S40697	(Get FASTA)	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

NM_019639

RefSeq Status:

VALIDATED

Type:

CODING

Protein Acc Id:

NP_062613

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	5	125,385,965 - 125,390,017	-	ENTREZGENE
Mouse cM Map	5		-	ENTREZGENE
Mouse Celera Assembly	5	122,405,521 - 122,411,999	-	RGD
Mouse Genome Assembly Build 37	5	125,866,335 - 125,870,387	-	RGD

Protein Sequences

Protein RefSeqs	NP_062613	(Get FASTA)
GenBank Protein	AAB22649	(Get FASTA)
	AAG00512	(Get FASTA)
	AAG00513	(Get FASTA)
	AAH06680	(Get FASTA)
	AAH08661	(Get FASTA)
	AAH21837	(Get FASTA)
	AAH25894	(Get FASTA)
	AAH36303	(Get FASTA)
	AAH94012	(Get FASTA)
	ABQ52426	(Get FASTA)
	BAA09096	(Get FASTA)
	BAB27296	(Get FASTA)
	BAE40351	(Get FASTA)
	EDL19560	(Get FASTA)
	EDL19561	(Get FASTA)
	P0CG50	(Get FASTA)

Promoters

RGD ID:

6838596

Promoter ID:

MM_KWN:44146

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, MEF_B4, MEF_B6

Transcripts:

EF580991_1_GM4802, EF580991_2_GM4802, EF580991_3_GM4802, EF580991_4_GM4802, EF580991_5_GM4802, EF580991_6_GM4802, UC008ZRG.1, UC008ZRM.1, UC008ZRN.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	5	125,867,211 - 125,869,142	-	MPROMDB

RGD ID:

6838590

Promoter ID:

MM_KWN:44147

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

AK132914_GM10382, OTTMUST00000085909

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	5	125,869,381 - 125,870,842	-	MPROMDB

RGD ID:

6879006

Promoter ID:

EPDNEW_M2954

Type:

preliminary

Name:

Ubc_1

Description:

ubiquitin C

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	5	125,869,561 - 125,869,621		EPDNEW

RGD ID:

6838570

Promoter ID:

MM_KWN:44148

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

BoneMarrow_4Hour

Transcripts:

ENSMUST00000091367, ENSMUST00000111388, OTTMUST00000085872, OTTMUST00000085908, UC008ZRH.1, UC008ZRI.1, UC008ZRJ.1, UC008ZRK.1, UC008ZRL.1

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	5	125,870,676 - 125,871,176	-	MPROMDB

RGD ID:

6847961

Promoter ID:

MM_ACW:39536

Type:

Non-CpG

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

UBC.DSEP07

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly Build 36.1	5	125,873,306 - 125,874,412	-	MPROMDB

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSMUSG00000008348	ENTREZGENE
Ensembl Protein	ENSMUSP00000115578	ENTREZGENE
Ensembl Transcript	ENSMUST00000156249	ENTREZGENE
Entrez Gene	22190	ENTREZGENE
Germonline	ENSMUSG00000008348
	ENSMUSG00000019505
	ENSMUSG00000020460
	ENSMUSG00000044285
	ENSMUSG00000058838
	ENSMUSG00000061390
	ENSMUSG00000063789
HomoloGene Group ID	128418	ENTREZGENE
InterPro	Ubiquitin	UniProtKB/Swiss-Prot
	Ubiquitin_CS	UniProtKB/Swiss-Prot
	Ubiquitin_subgr	UniProtKB/Swiss-Prot
	Ubiquitin_supergroup	UniProtKB/Swiss-Prot
IPI	IPI00918763	UniProtKB/TrEMBL
	IPI00923037	UniProtKB/TrEMBL
	IPI00969323	UniProtKB/Swiss-Prot
	IPI00988026	UniProtKB/TrEMBL
	IPI00988271	UniProtKB/TrEMBL
KEGG Report	mmu:22190	ENTREZGENE, UniProtKB/Swiss-Prot
MGD	MGI:98889	ENTREZGENE
Pfam	ubiquitin	UniProtKB/Swiss-Prot
PRINTS	UBIQUITIN	UniProtKB/Swiss-Prot
PROSITE	UBIQUITIN_1	UniProtKB/Swiss-Prot
	UBIQUITIN_2	UniProtKB/Swiss-Prot
SMART	UBQ	UniProtKB/Swiss-Prot
UniGene	Mm.331	ENTREZGENE
	Mm.419997	ENTREZGENE
UniProt	A5JUZ1_MOUSE	UniProtKB/TrEMBL
	E9Q5F6_MOUSE	UniProtKB/TrEMBL
	Q3TH47_MOUSE	UniProtKB/TrEMBL
	Q8R0Z9_MOUSE	UniProtKB/TrEMBL
	Q8VC46_MOUSE	UniProtKB/TrEMBL
	Q922B0_MOUSE	UniProtKB/TrEMBL
	Q922Z8_MOUSE	UniProtKB/TrEMBL
	UBC_MOUSE	UniProtKB/Swiss-Prot

More on Ubc
	Entrez Gene
	Ensembl Gene
	Genome Browser
	MGI Report
	NCBI Map Viewer
	Vista
	Vista + UCSC

RGD Object Information
RGD ID:	1624057
Created:	2007-05-02
Species:	Mus musculus
Last Modified:	2013-02-27
Status:	ACTIVE