Gene: Hspa5 (heat shock protein 5)  Mus musculus Symbol: Hspa5 Name: heat shock protein 5 Description: ENCODES a protein that exhibits misfolded protein binding; ribosome binding; protein domain specific binding (ortholog); INVOLVED IN activation of signaling protein activity involved in unfolded protein response; cellular response to interleukin-4; cerebellar Purkinje cell layer development; PARTICIPATES IN antigen processing and presentation pathway; Endoplasmic Reticulum-associated degradation pathway; prion diseases pathway; ASSOCIATED WITH abnormal alveolar lamellar body morphology; abnormal axon fasiculation; abnormal axon morphology; ASSOCIATED WITH Breast Neoplasms; Neuronal Ceroid-Lipofuscinoses; Pulmonary Fibrosis; FOUND IN cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 1H-pyrazole Type: protein-coding RefSeq Status: VALIDATED Also known as: 78 kDa glucose-regulated protein; AL022860; AU019543; baffled; Bip; D2Wsu141e; D2Wsu17e; glucose regulated protein, 78 kDa; GRP-78; Grp78; heat shock 70 kDa protein 5; heat shock 70kD protein 5 (glucose-regulated protein, 78kD); Hsce70; immunoglobulin heavy chain-binding protein; mBiP; OTTMUSP00000012896; OTTMUSP00000012897; SEZ-7; Sez7; XAP-1 antigen Orthologs: Homo sapiens : HSPA5 (heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa))  HGNC Rattus norvegicus : Hspa5 (heat shock protein 5) Related Pseudogenes: Gm7709   Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,772,090 - 34,776,529 + NCBI Mouse cM Map 2 22.94   NCBI Mouse Celera Assembly 2 34,472,567 - 34,477,006 + NCBI Mouse Genome Assembly Build 37 2 34,627,610 - 34,632,049 + NCBI Mouse Genome Assembly Build 36.1 2 34,627,615 - 34,631,977 + NCBI Mouse Cytogenetic Map 2 B   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Arthritis, Rheumatoid   ISS RGD:736447 5685639 protein:increased expression:synovial joint RGD   Autoimmune Diseases   ISS RGD:2843 5685668 protein:increased expression:heart RGD   Breast Neoplasms   IEP   5686342 protein:increased expression RGD   Dopamine beta hydroxylase deficiency   ISS RGD:736447 5685690   RGD   Glioma   ISS RGD:736447 5685704 protein:increased expression RGD   Infertility, Female   ISS RGD:736447 5685640   RGD   Inflammatory Bowel Diseases   ISS RGD:736447 5685671 protein:increased expression RGD   Nerve Degeneration   ISS RGD:2843 5685686 protein:decreased expression:spinal cord RGD   Neuronal Ceroid-Lipofuscinoses   IEP   5686293 protein:increased expression:brain RGD   Peripheral Nerve Injuries   ISS RGD:2843 5685664 mRNA:increased expression RGD   Pulmonary Fibrosis   IEP   5685632 mRNA,protein:increased expression:lungs RGD   Reperfusion Injury   ISS RGD:2843 5685650 associated with Diabetes Mellitus, experimental (D003921): protein:increased expression:brain RGD   Spinal Cord Injuries   IEP   5685666 mRNA: increased expression RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (R)-adrenaline multiple interactions ISO RGD:2843 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of HSPA5 protein CTD PMID:19464573 (R)-noradrenaline increases expression ISO RGD:2843 6480464 Norepinephrine results in increased expression of HSPA5 mRNA; more ... CTD PMID:16338971 (S)-nicotine multiple interactions ISO RGD:2843 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein] CTD PMID:18477628 1,3-dinitrobenzene increases metabolic processing ISO RGD:2843 6480464 3-dinitrobenzene results in increased metabolism of HSPA5 protein CTD PMID:21402099 1,4-dithiothreitol increases expression ISO RGD:736447 6480464 Dithiothreitol metabolite results in increased expression of HSPA5 protein CTD PMID:17416481 1,4-dithiothreitol increases expression ISO RGD:736447 6480464 Dithiothreitol results in increased expression of HSPA5 protein CTD PMID:21692457 1,4-dithiothreitol increases expression ISO RGD:736447 6480464 Dithiothreitol results in increased expression of HSPA5 mRNA CTD PMID:15710169 PMID:17332266 1,4-dithiothreitol increases expression ISO RGD:736447 6480464 Dithiothreitol results in increased expression of HSPA5 mRNA CTD PMID:17332266 PMID:15710169 1,4-dithiothreitol increases expression ISO RGD:2843 6480464 Dithiothreitol metabolite results in increased expression of HSPA5 protein CTD PMID:17416481 17alpha-ethynylestradiol affects expression EXP   6480464 Ethinyl Estradiol affects the expression of HSPA5 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:16174780 more ... 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:17942748 more ... 17alpha-ethynylestradiol increases expression ISO RGD:2843 6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:16174780 PMID:19400957 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:16174780 more ... 17alpha-ethynylestradiol increases expression ISO RGD:2843 6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:19400957 PMID:16174780 17alpha-ethynylestradiol affects expression ISO RGD:2843 6480464 Ethinyl Estradiol affects the expression of HSPA5 mRNA CTD PMID:20170705 17alpha-ethynylestradiol multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA5 mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of HSPA5 mRNA CTD PMID:17942748 more ... 17beta-estradiol increases expression EXP   6480464 Estradiol results in increased expression of HSPA5 mRNA CTD PMID:14664709 17beta-estradiol increases expression EXP   6480464 Estradiol results in increased expression of HSPA5 mRNA CTD PMID:14664709 PMID:17640991 17beta-estradiol increases expression EXP   6480464 Estradiol results in increased expression of HSPA5 protein CTD PMID:17640991 17beta-estradiol multiple interactions ISO RGD:736447 6480464 [Estradiol co-treated with ESR1 protein] results in increased expression of HSPA5 protein CTD PMID:19269315 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one affects localization ISO RGD:736447 6480464 Metribolone affects the localization of HSPA5 protein CTD PMID:17440980 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:736447 6480464 Metribolone results in increased expression of HSPA5 protein CTD PMID:17152098 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:736447 6480464 Metribolone promotes the reaction [NDRG1 protein binds to HSPA5 protein] CTD PMID:17220478 1H-pyrazole multiple interactions EXP   6480464 G6PDX affects the reaction [pyrazole results in increased expression of HSPA5 protein]; more ... CTD PMID:18068688 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 protein CTD PMID:12499123 more ... 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 protein CTD PMID:12499123 more ... 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 protein CTD PMID:14610226 more ... 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 protein CTD PMID:14610226 more ... 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 mRNA CTD PMID:17945193 PMID:14610226 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 protein CTD PMID:18068688 more ... 1H-pyrazole increases expression EXP   6480464 pyrazole results in increased expression of HSPA5 mRNA CTD PMID:14610226 PMID:17945193 2,2,2-tetramine multiple interactions ISO RGD:2843 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein] CTD PMID:19634143 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:736447 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSPA5 mRNA CTD PMID:16039398 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP   6480464 Tetrachlorodibenzodioxin affects the expression of HSPA5 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:2843 6480464 Tetrachlorodibenzodioxin affects the expression of HSPA5 mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2843 6480464 Tetrachlorodibenzodioxin results in increased expression of HSPA5 protein CTD PMID:12361703 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2843 6480464 Tetrachlorodibenzodioxin results in decreased expression of HSPA5 protein CTD PMID:16548065 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPA5 mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of HSPA5 mRNA CTD PMID:17942748 2,4,6-trinitrotoluene affects expression ISO RGD:2843 6480464 Trinitrotoluene affects the expression of HSPA5 mRNA CTD PMID:21346803 2,4-dinitrotoluene increases expression ISO RGD:736447 6480464 2,4-dinitrotoluene results in increased expression of HSPA5 mRNA CTD PMID:11409192 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:736447 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:2843 6480464 tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:2843 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:20165829 2-amino-2-deoxy-D-glucopyranose decreases expression EXP   6480464 Glucosamine results in decreased expression of HSPA5 mRNA CTD PMID:17178593 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... 2-deoxy-D-glucose multiple interactions ISO RGD:736447 6480464 ATG7 protein inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein]; more ... CTD PMID:20593179 2-deoxy-D-glucose increases expression ISO RGD:736447 6480464 Deoxyglucose results in increased expression of HSPA5 protein CTD PMID:20593179 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine decreases expression ISO RGD:2843 6480464 Puromycin Aminonucleoside results in decreased expression of HSPA5 protein CTD PMID:19264907 3H-1,2-dithiole-3-thione increases expression EXP   6480464 1,2-dithiol-3-thione results in increased expression of HSPA5 mRNA CTD PMID:15302862 3H-1,2-dithiole-3-thione decreases expression ISO RGD:2843 6480464 1,2-dithiol-3-thione results in decreased expression of HSPA5 mRNA CTD PMID:19162173 4-hydroxynon-2-enal affects binding ISO RGD:736447 6480464 4-hydroxy-2-nonenal analog binds to HSPA5 CTD PMID:18232660 4-hydroxyphenyl retinamide multiple interactions ISO RGD:736447 6480464 Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of HSPA5 protein] CTD PMID:17353921 4-hydroxyphenyl retinamide increases expression ISO RGD:736447 6480464 Fenretinide results in increased expression of HSPA5 protein CTD PMID:17353921 PMID:20546536 4-hydroxyphenyl retinamide decreases response to substance ISO RGD:736447 6480464 HSPA5 results in decreased susceptibility to Fenretinide CTD PMID:20546536 4-hydroxyphenyl retinamide increases expression ISO RGD:736447 6480464 Fenretinide results in increased expression of HSPA5 protein CTD PMID:20546536 PMID:17353921 4-phenylbutyric acid multiple interactions ISO RGD:2843 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] CTD PMID:20165829 4-phenylbutyric acid multiple interactions ISO RGD:736447 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] CTD PMID:20165829 4-phenylbutyric acid multiple interactions EXP   6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of HSPA5 protein] CTD PMID:17459145 7,12-dimethyltetraphene multiple interactions ISO RGD:2843 6480464 [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of HSPA5 protein CTD PMID:22248470 7,12-dimethyltetraphene increases expression ISO RGD:2843 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased expression of HSPA5 protein CTD PMID:22248470 7H-xanthine multiple interactions ISO RGD:2843 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of HSPA5 protein CTD PMID:19464573 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:736447 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of HSPA5 mRNA CTD PMID:22079614 9H-xanthine multiple interactions ISO RGD:2843 6480464 [Epinephrine co-treated with Xanthine co-treated with XDH] results in increased expression of HSPA5 protein CTD PMID:19464573 acetylsalicylic acid decreases expression ISO RGD:736447 6480464 Aspirin results in decreased expression of HSPA5 mRNA CTD PMID:14976132 acrolein increases expression ISO RGD:736447 6480464 Acrolein results in increased expression of HSPA5 protein CTD PMID:18951912 actinomycin D multiple interactions ISO RGD:2843 6480464 Dactinomycin inhibits the reaction [lead acetate results in increased expression of HSPA5 mRNA]; more ... CTD PMID:17915553 aflatoxin B1 decreases expression EXP   6480464 Aflatoxin B1 results in decreased expression of HSPA5 mRNA CTD PMID:19770486 aldehydo-D-glucosamine multiple interactions ISO RGD:736447 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... aldehydo-D-glucosamine multiple interactions ISO RGD:2843 6480464 tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 aldehydo-D-glucosamine increases expression ISO RGD:2843 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:20165829 aldehydo-D-glucosamine decreases expression EXP   6480464 Glucosamine results in decreased expression of HSPA5 mRNA CTD PMID:17178593 aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... aldehydo-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... all-trans-retinoic acid multiple interactions ISO RGD:736447 6480464 MGAT5 protein inhibits the reaction [Tretinoin results in increased expression of HSPA5 protein] CTD PMID:17031849 all-trans-retinoic acid increases expression EXP   6480464 Tretinoin results in increased expression of HSPA5 protein; more ... CTD PMID:22498432 all-trans-retinoic acid increases expression ISO RGD:2843 6480464 Tretinoin results in increased expression of HSPA5 mRNA CTD PMID:20488242 all-trans-retinoic acid increases expression ISO RGD:736447 6480464 Tretinoin results in increased expression of HSPA5 protein CTD PMID:17031849 PMID:19960509 all-trans-retinoic acid increases expression ISO RGD:736447 6480464 Tretinoin results in increased expression of HSPA5 protein CTD PMID:19960509 PMID:17031849 amiloride multiple interactions EXP   6480464 Amiloride inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein]; more ... CTD PMID:20015086 ammonium chloride affects expression ISO RGD:2843 6480464 Ammonium Chloride affects the expression of HSPA5 mRNA CTD PMID:16483693 aniline increases nitrosation ISO RGD:2843 6480464 aniline results in increased nitrosation of HSPA5 protein CTD PMID:21708182 antimycin A increases expression ISO RGD:2843 6480464 Antimycin A results in increased expression of HSPA5 protein CTD PMID:21337367 apigenin multiple interactions EXP   6480464 Apigenin inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; more ... CTD PMID:20493918 apigenin decreases expression EXP   6480464 Apigenin results in decreased expression of HSPA5 mRNA CTD PMID:22359648 aristolochic acid increases expression ISO RGD:736447 6480464 aristolochic acid I results in increased expression of HSPA5 CTD PMID:22445861 arsenic atom increases expression ISO RGD:736447 6480464 Arsenic results in increased expression of HSPA5 protein CTD PMID:19818359 arsenic atom decreases expression EXP   6480464 Arsenic results in decreased expression of HSPA5 protein CTD PMID:22552367 arsenite(3-) multiple interactions EXP   6480464 TRP53 protein affects the reaction [arsenite results in decreased expression of HSPA5 mRNA] CTD PMID:18929588 arsenite(3-) increases expression ISO RGD:736447 6480464 arsenite results in increased expression of HSPA5 protein CTD PMID:22959463 arsenite(3-) increases expression EXP   6480464 arsenite results in increased expression of HSPA5 mRNA CTD PMID:22215663 arsenite(3-) multiple interactions EXP   6480464 2-(methylamino)isobutyric acid inhibits the reaction [arsenite results in increased expression of HSPA5 mRNA] CTD PMID:22215663 arsenite(3-) decreases expression EXP   6480464 arsenite results in decreased expression of HSPA5 mRNA CTD PMID:18929588 atrazine multiple interactions ISO RGD:736447 6480464 Atrazine promotes the reaction [arsenic trioxide results in increased expression of HSPA5 mRNA] CTD PMID:11678611 benzene increases expression ISO RGD:736447 6480464 Benzene results in increased expression of HSPA5 protein CTD PMID:12183065 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of HSPA5 mRNA CTD PMID:21715664 PMID:19770486 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of HSPA5 mRNA CTD PMID:21569818 PMID:22228805 benzo[a]pyrene decreases expression ISO RGD:736447 6480464 Benzo(a)pyrene results in decreased expression of HSPA5 mRNA CTD PMID:21632981 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of HSPA5 mRNA CTD PMID:21569818 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of HSPA5 mRNA CTD PMID:19770486 PMID:21715664 benzo[a]pyrene multiple interactions ISO RGD:2843 6480464 Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of HSPA5 mRNA] CTD PMID:17915553 benzo[a]pyrene increases expression ISO RGD:2843 6480464 Benzo(a)pyrene results in increased expression of HSPA5 mRNA CTD PMID:17915553 benzo[a]pyrene multiple interactions EXP   6480464 [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of HSPA5 mRNA CTD PMID:21715664 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of HSPA5 protein CTD PMID:17915553 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of HSPA5 mRNA CTD PMID:21715664 beta-D-glucosamine multiple interactions ISO RGD:736447 6480464 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:16380481 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:16380481 more ... beta-D-glucosamine multiple interactions ISO RGD:2843 6480464 tauroursodeoxycholic acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; more ... CTD PMID:20165829 beta-D-glucosamine increases expression ISO RGD:2843 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:20165829 beta-D-glucosamine decreases expression EXP   6480464 Glucosamine results in decreased expression of HSPA5 mRNA CTD PMID:17178593 beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 protein CTD PMID:15618547 more ... beta-D-glucosamine increases expression ISO RGD:736447 6480464 Glucosamine results in increased expression of HSPA5 mRNA CTD PMID:19383982 more ... bifenthrin increases expression ISO RGD:736447 6480464 bifenthrin results in increased expression of HSPA5 protein CTD PMID:16271832 bilirubin increases expression ISO RGD:736447 6480464 Bilirubin results in increased expression of HSPA5 mRNA CTD PMID:20196124 bis(2-chloroethyl) sulfide increases expression EXP   6480464 Mustard Gas results in increased expression of HSPA5 mRNA CTD PMID:15674843 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:2843 6480464 Diethylhexyl Phthalate results in decreased expression of HSPA5 protein CTD PMID:16400681 bis(2-ethylhexyl) phthalate increases expression ISO RGD:2843 6480464 Diethylhexyl Phthalate results in increased expression of HSPA5 mRNA CTD PMID:21318169 bis(2-ethylhexyl) phthalate decreases expression EXP   6480464 Diethylhexyl Phthalate results in decreased expression of HSPA5 mRNA CTD PMID:21318169 bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:20807545 more ... bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:12233820 more ... bisphenol A multiple interactions ISO RGD:736447 6480464 [bisphenol A co-treated with ESR1 protein] results in increased expression of HSPA5 protein CTD PMID:19269315 bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:12732195 more ... bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:12732195 more ... bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:20807545 more ... bisphenol A affects expression ISO RGD:736447 6480464 bisphenol A affects the expression of HSPA5 mRNA CTD PMID:20170705 bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of HSPA5 mRNA CTD PMID:16713995 more ... brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 protein CTD PMID:18723477 more ... brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 protein CTD PMID:18723477 more ... brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 mRNA CTD PMID:12147617 PMID:19428936 brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 protein CTD PMID:20626587 more ... brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 protein CTD PMID:19428936 more ... brefeldin A increases expression ISO RGD:736447 6480464 Brefeldin A results in increased expression of HSPA5 mRNA CTD PMID:19428936 brefeldin A increases expression EXP   6480464 Brefeldin A results in increased expression of HSPA5 protein CTD PMID:20493918 brefeldin A multiple interactions ISO RGD:736447 6480464 bortezomib inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein] CTD PMID:18723477 brefeldin A multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; more ... CTD PMID:20493918 bromobenzene decreases expression ISO RGD:2843 6480464 bromobenzene results in decreased expression of HSPA5 mRNA CTD PMID:15056800 bromobenzene increases expression ISO RGD:2843 6480464 bromobenzene results in increased expression of HSPA5 mRNA CTD PMID:12628495 bupropion increases expression ISO RGD:736447 6480464 Bupropion results in increased expression of HSPA5 protein CTD PMID:21354251 cadmium atom increases expression ISO RGD:736447 6480464 Cadmium results in increased expression of HSPA5 protein CTD PMID:20600546 cadmium atom increases expression ISO RGD:736447 6480464 Cadmium results in increased expression of HSPA5 mRNA CTD PMID:16020198 PMID:21694771 cadmium atom increases expression ISO RGD:736447 6480464 Cadmium results in increased expression of HSPA5 mRNA CTD PMID:16020198 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA5 protein CTD PMID:21325019 PMID:21908765 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA5 mRNA CTD PMID:15081267 PMID:17464326 cadmium dichloride multiple interactions EXP   6480464 LL Z1640-2 inhibits the reaction [Cadmium Chloride results in increased expression of HSPA5 mRNA] CTD PMID:15081267 cadmium dichloride increases expression ISO RGD:2843 6480464 Cadmium Chloride results in increased expression of HSPA5 mRNA CTD PMID:18636176 cadmium dichloride increases expression ISO RGD:736447 6480464 Cadmium Chloride results in increased expression of HSPA5 protein CTD PMID:21809093 cadmium dichloride increases expression ISO RGD:736447 6480464 Cadmium Chloride results in increased expression of HSPA5 mRNA CTD PMID:18560533 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA5 mRNA CTD PMID:17464326 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA5 protein CTD PMID:21908765 PMID:21325019 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of HSPA5 protein CTD PMID:21325019 cadmium sulfate increases expression ISO RGD:736447 6480464 cadmium sulfate results in increased expression of HSPA5 mRNA CTD PMID:12064557 capsaicin increases localization ISO RGD:736447 6480464 Capsaicin results in increased localization of HSPA5 protein CTD PMID:19331147 capsaicin increases expression ISO RGD:736447 6480464 Capsaicin results in increased expression of HSPA5 protein CTD PMID:19139269 PMID:19699254 capsaicin increases expression ISO RGD:736447 6480464 Capsaicin results in increased expression of HSPA5 CTD PMID:21859781 capsaicin increases expression ISO RGD:736447 6480464 Capsaicin results in increased expression of HSPA5 protein CTD PMID:19699254 PMID:19139269 carbaryl increases expression ISO RGD:736447 6480464 Carbaryl results in increased expression of HSPA5 mRNA CTD PMID:11226373 carboplatin decreases expression ISO RGD:2843 6480464 Carboplatin results in decreased expression of HSPA5 mRNA CTD PMID:18172885 celastrol increases expression ISO RGD:736447 6480464 tripterine results in increased expression of HSPA5 mRNA CTD PMID:17010675 celecoxib increases expression ISO RGD:736447 6480464 celecoxib results in increased expression of HSPA5 CTD PMID:21567098 chlordecone increases expression EXP   6480464 Chlordecone results in increased expression of HSPA5 mRNA; more ... CTD PMID:17640991 chlordecone multiple interactions EXP   6480464 Chlordecone promotes the reaction [ESR1 protein binds to HSPA5 protein]; more ... CTD PMID:17640991 chlordecone increases response to substance EXP   6480464 HSPA5 protein results in increased susceptibility to Chlordecone CTD PMID:17640991 chlorhexidine increases expression EXP   6480464 Chlorhexidine results in increased expression of HSPA5 protein CTD PMID:19027770 chlorobenzene increases expression ISO RGD:736447 6480464 chlorobenzene results in increased expression of HSPA5 protein CTD PMID:12183065 chloropicrin increases expression ISO RGD:736447 6480464 chloropicrin results in increased expression of HSPA5 protein CTD PMID:22516760 chlorpyrifos increases expression EXP   6480464 Chlorpyrifos results in increased expression of HSPA5 mRNA CTD PMID:22515965 choline affects expression ISO RGD:736447 6480464 Choline affects the expression of HSPA5 mRNA CTD PMID:17616785 choline multiple interactions EXP   6480464 Tamoxifen inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of HSPA5 protein] CTD PMID:23038002 choline multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HSPA5 gene CTD PMID:20938992 chrysazin increases expression ISO RGD:736447 6480464 danthron results in increased expression of HSPA5 protein CTD PMID:21126053 cisplatin increases expression ISO RGD:736447 6480464 Cisplatin results in increased expression of HSPA5 protein CTD PMID:16357177 cisplatin increases expression ISO RGD:736447 6480464 Cisplatin results in increased expression of HSPA5 mRNA CTD PMID:19561079 cisplatin decreases expression ISO RGD:736447 6480464 Cisplatin results in decreased expression of HSPA5 mRNA CTD PMID:11099651 cisplatin affects expression ISO RGD:2843 6480464 Cisplatin affects the expression of HSPA5 protein CTD PMID:20071420 cisplatin decreases expression EXP   6480464 Cisplatin results in decreased expression of HSPA5 mRNA CTD PMID:21151649 clofibrate decreases expression EXP   6480464 Clofibrate results in decreased expression of HSPA5 mRNA CTD PMID:17585979 clofibrate decreases expression ISO RGD:2843 6480464 Clofibrate results in decreased expression of HSPA5 mRNA CTD PMID:21318169 cobalt dichloride increases expression ISO RGD:2843 6480464 cobaltous chloride results in increased expression of HSPA5 protein CTD PMID:21337367 cocaine increases expression ISO RGD:736447 6480464 Cocaine results in increased expression of HSPA5 mRNA CTD PMID:15009677 cocaine increases expression ISO RGD:2843 6480464 Cocaine results in increased expression of HSPA5 protein CTD PMID:17303341 cocaine multiple interactions ISO RGD:2843 6480464 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; more ... CTD PMID:17303341 copper atom multiple interactions ISO RGD:736447 6480464 [NSC 689534 binds to Copper] which results in increased expression of HSPA5 mRNA CTD PMID:20971185 copper atom affects binding ISO RGD:736447 6480464 HSPA5 protein binds to Copper CTD PMID:14534351 PMID:15359738 copper atom increases expression ISO RGD:736447 6480464 Copper results in increased expression of HSPA5 protein CTD PMID:15836927 PMID:22692975 copper atom increases expression ISO RGD:736447 6480464 Copper results in increased expression of HSPA5 protein CTD PMID:15836927 copper atom affects binding ISO RGD:736447 6480464 HSPA5 protein binds to Copper CTD PMID:15359738 copper(0) multiple interactions ISO RGD:736447 6480464 [NSC 689534 binds to Copper] which results in increased expression of HSPA5 mRNA CTD PMID:20971185 copper(0) increases expression ISO RGD:736447 6480464 Copper results in increased expression of HSPA5 protein CTD PMID:15836927 PMID:22692975 copper(0) affects binding ISO RGD:736447 6480464 HSPA5 protein binds to Copper CTD PMID:14534351 PMID:15359738 copper(0) increases expression ISO RGD:736447 6480464 Copper results in increased expression of HSPA5 protein CTD PMID:15836927 copper(0) affects binding ISO RGD:736447 6480464 HSPA5 protein binds to Copper CTD PMID:15359738 copper(2+) sulfate decreases expression ISO RGD:736447 6480464 Copper Sulfate results in decreased expression of HSPA5 mRNA CTD PMID:19549813 copper(II) chloride multiple interactions ISO RGD:2843 6480464 [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; more ... CTD PMID:20920558 curcumin increases expression EXP   6480464 Curcumin results in increased expression of HSPA5 mRNA CTD PMID:18200517 cycloheximide multiple interactions ISO RGD:2843 6480464 Cycloheximide inhibits the reaction [lead acetate results in increased expression of HSPA5 protein]; more ... CTD PMID:17915553 cycloheximide multiple interactions ISO RGD:2843 6480464 Cycloheximide inhibits the reaction [GIF 0010 results in increased expression of HSPA5 mRNA] CTD PMID:9742210 cyclophosphamide decreases expression ISO RGD:2843 6480464 Cyclophosphamide results in decreased expression of HSPA5 mRNA CTD PMID:11906922 cyclosporin A increases expression ISO RGD:736447 6480464 Cyclosporine results in increased expression of HSPA5 mRNA CTD PMID:21163907 PMID:20106945 cyclosporin A increases expression EXP   6480464 Cyclosporine results in increased expression of HSPA5 protein CTD PMID:22155090 cyclosporin A multiple interactions EXP   6480464 2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole inhibits the reaction [Cyclosporine results in increased expression of HSPA5 protein] CTD PMID:22155090 cyclosporin A increases expression ISO RGD:736447 6480464 Cyclosporine results in increased expression of HSPA5 mRNA CTD PMID:19159671 more ... cyclosporin A increases expression ISO RGD:736447 6480464 Cyclosporine results in increased expression of HSPA5 mRNA CTD PMID:20106945 PMID:21163907 cyclosporin A multiple interactions ISO RGD:2843 6480464 Melatonin promotes the reaction [Cyclosporine results in increased expression of HSPA5 protein] CTD PMID:20136702 cyclosporin A increases expression ISO RGD:2843 6480464 Cyclosporine results in increased expression of HSPA5 protein CTD PMID:20136702 D-glucose increases expression ISO RGD:736447 6480464 Glucose results in increased expression of HSPA5 mRNA CTD PMID:16380481 D-glucose increases expression ISO RGD:736447 6480464 Glucose deficiency results in increased expression of HSPA5 mRNA CTD PMID:12147617 D-glucose increases expression ISO RGD:2843 6480464 Glucose deficiency results in increased expression of HSPA5 protein CTD PMID:21337367 D-glucose decreases expression EXP   6480464 Glucose results in decreased expression of HSPA5 mRNA CTD PMID:17178593 D-mannopyranose multiple interactions ISO RGD:736447 6480464 Mannose inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein] CTD PMID:20593179 D-penicillamine increases expression ISO RGD:736447 6480464 Penicillamine results in increased expression of HSPA5 protein CTD PMID:19722195 DDT increases expression ISO RGD:736447 6480464 DDT results in increased expression of HSPA5 mRNA CTD PMID:15710169 Delta(9)-tetrahydrocannabinol increases expression ISO RGD:736447 6480464 Tetrahydrocannabinol results in increased expression of HSPA5 protein CTD PMID:18163980 Delta(9)-tetrahydrocannabinol increases expression ISO RGD:2843 6480464 Tetrahydrocannabinol results in increased expression of HSPA5 mRNA CTD PMID:16616335 Delta(9)-tetrahydrocannabinol decreases expression ISO RGD:736447 6480464 Tetrahydrocannabinol results in decreased expression of HSPA5 mRNA CTD PMID:16039398 deoxycholic acid decreases response to substance ISO RGD:736447 6480464 HSPA5 protein results in decreased susceptibility to Deoxycholic Acid CTD PMID:12507930 diamminedichloroplatinum decreases expression ISO RGD:736447 6480464 transplatin results in decreased expression of HSPA5 mRNA CTD PMID:11099651 diarsenic trioxide increases expression ISO RGD:736447 6480464 arsenic trioxide results in increased expression of HSPA5 mRNA CTD PMID:19695276 PMID:11678611 diarsenic trioxide multiple interactions ISO RGD:2843 6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSPA5 protein] CTD PMID:21145380 diarsenic trioxide increases expression ISO RGD:2843 6480464 arsenic trioxide results in increased expression of HSPA5 protein CTD PMID:21145380 diarsenic trioxide increases expression EXP   6480464 arsenic trioxide results in increased expression of HSPA5 mRNA CTD PMID:21533816 diarsenic trioxide multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSPA5 mRNA] CTD PMID:21533816 diarsenic trioxide affects response to substance ISO RGD:736447 6480464 HSPA5 protein affects the susceptibility to arsenic trioxide CTD PMID:19695276 diarsenic trioxide multiple interactions ISO RGD:736447 6480464 Atrazine promotes the reaction [arsenic trioxide results in increased expression of HSPA5 mRNA] CTD PMID:11678611 diarsenic trioxide increases expression ISO RGD:736447 6480464 arsenic trioxide results in increased expression of HSPA5 protein CTD PMID:19695276 diarsenic trioxide increases expression ISO RGD:736447 6480464 arsenic trioxide results in increased expression of HSPA5 mRNA CTD PMID:11678611 PMID:19695276 diazinon increases expression EXP   6480464 Diazinon results in increased expression of HSPA5 protein CTD PMID:19647006 diazoxide increases expression EXP   6480464 Isoproterenol results in increased expression of HSPA5 mRNA CTD PMID:21335049 dichlorine multiple interactions ISO RGD:2843 6480464 [Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA CTD PMID:18636392 dicoumarol multiple interactions ISO RGD:736447 6480464 Dicumarol inhibits the reaction [1-nitropyrene results in increased expression of HSPA5 protein] CTD PMID:19460413 diethyl maleate decreases reduction EXP   6480464 diethyl maleate results in decreased reduction of HSPA5 protein CTD PMID:19843705 dihydrocapsaicin increases expression ISO RGD:736447 6480464 dihydrocapsaicin results in increased expression of HSPA5 protein CTD PMID:19139269 diisopropyl fluorophosphate decreases expression ISO RGD:736447 6480464 Isoflurophate results in decreased expression of HSPA5 protein CTD PMID:17223147 dimethylarsinic acid increases expression ISO RGD:2843 6480464 Cacodylic Acid results in increased expression of HSPA5 mRNA CTD PMID:16122865 dioxygen multiple interactions ISO RGD:736447 6480464 Oxygen deficiency inhibits the reaction [Deoxyglucose results in increased expression of HSPA5 protein] CTD PMID:20593179 dioxygen increases expression ISO RGD:2843 6480464 Oxygen deficiency results in increased expression of HSPA5 protein CTD PMID:21337367 PMID:22226148 dioxygen increases expression ISO RGD:2843 6480464 Oxygen deficiency results in increased expression of HSPA5 protein CTD PMID:22226148 PMID:21337367 dioxygen increases expression ISO RGD:2843 6480464 Oxygen deficiency results in increased expression of HSPA5 mRNA; more ... CTD PMID:22226148 dioxygen multiple interactions ISO RGD:2843 6480464 4-chlorobenzyltetrahydroberberine inhibits the reaction [Oxygen deficiency results in increased expression of HSPA5 mRNA]; more ... CTD PMID:22226148 diuron decreases expression ISO RGD:2843 6480464 Diuron results in decreased expression of HSPA5 mRNA CTD PMID:21551480 doxorubicin increases expression ISO RGD:736447 6480464 Doxorubicin results in increased expression of HSPA5 mRNA CTD PMID:17680992 doxorubicin multiple interactions ISO RGD:736447 6480464 Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] CTD PMID:16298333 endosulfan increases expression ISO RGD:736447 6480464 Endosulfan results in increased expression of HSPA5 protein CTD PMID:16884889 ethanol increases expression EXP   6480464 Ethanol results in increased expression of HSPA5 protein CTD PMID:18377926 ethylbenzene increases expression ISO RGD:736447 6480464 ethylbenzene results in increased expression of HSPA5 protein CTD PMID:12183065 folic acid multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HSPA5 gene CTD PMID:20938992 formetanate increases expression ISO RGD:736447 6480464 formetanate results in increased expression of HSPA5 protein CTD PMID:16271832 fructose increases expression EXP   6480464 Fructose results in increased expression of HSPA5 mRNA; more ... CTD PMID:22698815 fructose multiple interactions EXP   6480464 Phenylbutyrates inhibits the reaction [Fructose results in increased expression of HSPA5 protein] CTD PMID:22698815 fulvestrant multiple interactions EXP   6480464 [Chlordecone co-treated with fulvestrant] results in increased expression of HSPA5 protein CTD PMID:17640991 furan affects binding ISO RGD:2843 6480464 furan binds to HSPA5 protein CTD PMID:22240984 gadolinium trichloride increases expression ISO RGD:2843 6480464 gadolinium chloride results in increased expression of HSPA5 protein CTD PMID:21198628 gadolinium trichloride multiple interactions ISO RGD:2843 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein] CTD PMID:21198628 gadolinium trichloride affects expression ISO RGD:2843 6480464 gadolinium chloride affects the expression of HSPA5 mRNA CTD PMID:21198628 galactose multiple interactions ISO RGD:736447 6480464 Phycocyanin inhibits the reaction [Galactose results in increased expression of HSPA5 protein] CTD PMID:23036742 galactose increases expression ISO RGD:736447 6480464 Galactose results in increased expression of HSPA5 protein CTD PMID:23036742 gedunin increases expression ISO RGD:736447 6480464 gedunin results in increased expression of HSPA5 mRNA CTD PMID:17010675 geldanamycin multiple interactions ISO RGD:736447 6480464 bortezomib promotes the reaction [geldanamycin results in increased expression of HSPA5 protein]; more ... CTD PMID:15141013 geldanamycin increases expression ISO RGD:736447 6480464 geldanamycin results in increased expression of HSPA5 protein CTD PMID:15141013 geldanamycin affects expression ISO RGD:736447 6480464 geldanamycin affects the expression of HSPA5 protein CTD PMID:14576064 glucose increases expression ISO RGD:736447 6480464 Glucose results in increased expression of HSPA5 mRNA CTD PMID:16380481 glucose increases expression ISO RGD:736447 6480464 Glucose deficiency results in increased expression of HSPA5 mRNA CTD PMID:12147617 glucose increases expression ISO RGD:2843 6480464 Glucose deficiency results in increased expression of HSPA5 protein CTD PMID:21337367 glucose decreases expression EXP   6480464 Glucose results in decreased expression of HSPA5 mRNA CTD PMID:17178593 glutathione multiple interactions EXP   6480464 Glutathione inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; more ... CTD PMID:20493918 graphite increases expression ISO RGD:736447 6480464 Graphite results in increased expression of HSPA5 protein CTD PMID:22157353 hyaluronic acid affects expression ISO RGD:2843 6480464 Hyaluronic Acid analog affects the expression of HSPA5 protein CTD PMID:23178681 hyaluronic acid multiple interactions ISO RGD:2843 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA5 protein] CTD PMID:23178681 hydrazine increases expression ISO RGD:2843 6480464 hydrazine results in increased expression of HSPA5 mRNA; more ... CTD PMID:15370871 hydrogen peroxide increases expression ISO RGD:736447 6480464 Hydrogen Peroxide results in increased expression of HSPA5 protein CTD PMID:22269385 hydrogen peroxide decreases expression ISO RGD:2843 6480464 Hydrogen Peroxide results in decreased expression of HSPA5 protein CTD PMID:23178681 hydrogen peroxide multiple interactions ISO RGD:2843 6480464 Hyaluronic Acid analog inhibits the reaction [Hydrogen Peroxide results in decreased expression of HSPA5 protein] CTD PMID:23178681 imidacloprid decreases expression ISO RGD:736447 6480464 imidacloprid results in decreased expression of HSPA5 protein CTD PMID:16884889 indomethacin multiple interactions ISO RGD:736447 6480464 anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Indomethacin results in increased expression of HSPA5 protein]; more ... CTD PMID:17341418 indomethacin increases expression ISO RGD:2843 6480464 Indomethacin results in increased expression of HSPA5 mRNA CTD PMID:18799549 indomethacin increases expression EXP   6480464 Indomethacin results in increased expression of HSPA5 mRNA CTD PMID:18799549 indomethacin increases expression ISO RGD:736447 6480464 Indomethacin results in increased expression of HSPA5 protein CTD PMID:17341418 ionomycin multiple interactions EXP   6480464 deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; more ... CTD PMID:10652249 iprodione increases expression ISO RGD:736447 6480464 iprodione results in increased expression of HSPA5 mRNA CTD PMID:16696176 isoprenaline increases expression EXP   6480464 Isoproterenol results in increased expression of HSPA5 mRNA CTD PMID:21335049 ketamine decreases expression ISO RGD:2843 6480464 Ketamine results in decreased expression of HSPA5 mRNA CTD PMID:20080153 kojic acid multiple interactions ISO RGD:2843 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA5 mRNA CTD PMID:18544905 L-ascorbic acid multiple interactions ISO RGD:736447 6480464 Ascorbic Acid inhibits the reaction [Fenretinide results in increased expression of HSPA5 protein] CTD PMID:17353921 L-ascorbic acid decreases expression ISO RGD:736447 6480464 Ascorbic Acid results in decreased expression of HSPA5 mRNA CTD PMID:19197388 L-methionine multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of HSPA5 gene CTD PMID:20938992 L-methionine multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of HSPA5 protein; more ... CTD PMID:23038002 lactacystin multiple interactions ISO RGD:736447 6480464 HSPA5 promotes the reaction [lactacystin results in increased expression of APOB protein]; more ... CTD PMID:15618547 lanthanum atom multiple interactions ISO RGD:736447 6480464 Lanthanum binds to and results in increased expression of HSPA5 protein CTD PMID:18773883 lead diacetate multiple interactions ISO RGD:2843 6480464 Cycloheximide inhibits the reaction [lead acetate results in increased expression of HSPA5 protein]; more ... CTD PMID:17915553 lead diacetate increases expression ISO RGD:2843 6480464 lead acetate results in increased expression of HSPA5 protein CTD PMID:10702365 PMID:17915553 lead diacetate increases expression ISO RGD:2843 6480464 lead acetate results in increased expression of HSPA5 protein CTD PMID:17915553 PMID:10702365 lead diacetate affects binding ISO RGD:2843 6480464 lead acetate binds to HSPA5 protein CTD PMID:10702365 lead diacetate multiple interactions ISO RGD:2843 6480464 ATP7A protein modified form inhibits the reaction [lead acetate binds to HSPA5 protein]; more ... CTD PMID:10702365 lead diacetate increases expression ISO RGD:2843 6480464 lead acetate results in increased expression of HSPA5 mRNA; more ... CTD PMID:17915553 lead diacetate multiple interactions ISO RGD:2843 6480464 lead acetate inhibits the reaction [HSPA5 protein binds to HRAS enhancer]; more ... CTD PMID:15111246 lead diacetate affects expression ISO RGD:2843 6480464 lead acetate affects the expression of HSPA5 mRNA CTD PMID:15111246 lead(0) affects expression ISO RGD:2843 6480464 Lead affects the expression of HSPA5 mRNA CTD PMID:15111246 lead(0) increases expression ISO RGD:736447 6480464 Lead results in increased expression of HSPA5 mRNA CTD PMID:11032763 lead(0) increases expression ISO RGD:2843 6480464 Lead results in increased expression of HSPA5 protein CTD PMID:19161237 lead(0) multiple interactions ISO RGD:2843 6480464 Lead inhibits the reaction [HSPA5 protein binds to HRAS enhancer]; more ... CTD PMID:15111246 lithium atom increases expression ISO RGD:2843 6480464 Lithium results in increased expression of HSPA5 mRNA; more ... CTD PMID:16236328 LY294002 multiple interactions ISO RGD:736447 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA] CTD PMID:19428936 maneb multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in increased expression of HSPA5 mRNA CTD PMID:18386188 manganese atom increases expression ISO RGD:736447 6480464 Manganese results in increased expression of HSPA5 protein CTD PMID:21477646 manganese(0) increases expression ISO RGD:736447 6480464 Manganese results in increased expression of HSPA5 protein CTD PMID:21477646 meglumine amidotrizoate increases expression ISO RGD:2843 6480464 Diatrizoate Meglumine results in increased expression of HSPA5 protein CTD PMID:20071420 melatonin multiple interactions ISO RGD:2843 6480464 Melatonin promotes the reaction [Cyclosporine results in increased expression of HSPA5 protein] CTD PMID:20136702 menadione multiple interactions ISO RGD:736447 6480464 S 3483 promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein]; more ... CTD PMID:19819344 menadione increases expression ISO RGD:736447 6480464 Vitamin K 3 results in increased expression of HSPA5 protein CTD PMID:19819344 mercury atom multiple interactions ISO RGD:2843 6480464 Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer]; more ... CTD PMID:15111246 mercury atom affects expression ISO RGD:2843 6480464 Mercury affects the expression of HSPA5 mRNA CTD PMID:15111246 mercury dichloride multiple interactions ISO RGD:2843 6480464 Cycloheximide inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 protein]; more ... CTD PMID:17915553 mercury dichloride increases expression ISO RGD:2843 6480464 Mercuric Chloride results in increased expression of HSPA5 mRNA; more ... CTD PMID:17915553 mercury dichloride multiple interactions ISO RGD:2843 6480464 Mercuric Chloride promotes the reaction [HSPA5 protein binds to FOS enhancer]; more ... CTD PMID:15111246 mercury dichloride affects expression ISO RGD:2843 6480464 Mercuric Chloride affects the expression of HSPA5 mRNA CTD PMID:15111246 mercury(0) multiple interactions ISO RGD:2843 6480464 Mercury promotes the reaction [HSPA5 protein binds to HRAS enhancer]; more ... CTD PMID:15111246 mercury(0) affects expression ISO RGD:2843 6480464 Mercury affects the expression of HSPA5 mRNA CTD PMID:15111246 methamphetamine affects expression ISO RGD:2843 6480464 Methamphetamine affects the expression of HSPA5 protein CTD PMID:19826936 methapyrilene increases expression ISO RGD:2843 6480464 Methapyrilene results in increased expression of HSPA5 mRNA CTD PMID:15120968 PMID:17450226 methapyrilene increases expression ISO RGD:2843 6480464 Methapyrilene results in increased expression of HSPA5 mRNA CTD PMID:17450226 PMID:15120968 methomyl increases expression ISO RGD:736447 6480464 Methomyl results in increased expression of HSPA5 protein CTD PMID:16271832 metyrapone multiple interactions ISO RGD:736447 6480464 Metyrapone promotes the reaction [Vitamin K 3 results in increased expression of HSPA5 protein] CTD PMID:19819344 minocycline multiple interactions ISO RGD:2843 6480464 Minocycline inhibits the reaction [Paraquat results in increased expression of HSPA5 protein] CTD PMID:22245251 N,N-dimethylformamide multiple interactions ISO RGD:2843 6480464 [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 mRNA; more ... CTD PMID:20097184 N-acetyl-L-cysteine increases expression ISO RGD:736447 6480464 Acetylcysteine results in increased expression of HSPA5 protein CTD PMID:19722195 N-acetyl-L-cysteine multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein] CTD PMID:21911445 N-acetyl-L-cysteine multiple interactions ISO RGD:2843 6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSPA5 protein] CTD PMID:21145380 N-acetyl-L-cysteine multiple interactions ISO RGD:2843 6480464 Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein] CTD PMID:21198628 N-acetyl-L-cysteine multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; more ... CTD PMID:20493918 N-acetyl-L-cysteine multiple interactions EXP   6480464 Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSPA5 mRNA] CTD PMID:21533816 N-methyl-4-phenylpyridinium increases expression ISO RGD:2843 6480464 1-Methyl-4-phenylpyridinium results in increased expression of HSPA5 mRNA CTD PMID:16026605 N-nitrosodiethylamine multiple interactions ISO RGD:2843 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA5 mRNA CTD PMID:18544905 N-nitrosodiethylamine decreases expression ISO RGD:2843 6480464 Diethylnitrosamine results in decreased expression of HSPA5 mRNA CTD PMID:11323195 naphthalene affects binding EXP   6480464 naphthalene metabolite binds to HSPA5 protein CTD PMID:16206326 naphthalene increases reduction EXP   6480464 naphthalene results in increased reduction of HSPA5 protein CTD PMID:19843705 nickel atom multiple interactions ISO RGD:2843 6480464 Nickel inhibits the reaction [lead acetate binds to HSPA5 protein] CTD PMID:10702365 nifedipine multiple interactions ISO RGD:2843 6480464 Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of HSPA5 mRNA]; more ... CTD PMID:22226148 nitric oxide multiple interactions ISO RGD:736447 6480464 [NOS3 protein polymorphism results in decreased chemical synthesis of Nitric Oxide] which results in decreased expression of HSPA5 mRNA; more ... CTD PMID:19320461 ochratoxin A decreases expression EXP   6480464 ochratoxin A results in decreased expression of HSPA5 protein CTD PMID:19445961 ochratoxin A decreases expression ISO RGD:736447 6480464 ochratoxin A results in decreased expression of HSPA5 mRNA CTD PMID:19051279 ozone multiple interactions ISO RGD:2843 6480464 [Ozone co-treated with Chlorine] results in decreased expression of HSPA5 mRNA CTD PMID:18636392 ozone increases expression EXP   6480464 Ozone results in increased expression of HSPA5 mRNA CTD PMID:21543283 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of HSPA5 mRNA CTD PMID:17562736 PMID:15606129 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of HSPA5 mRNA CTD PMID:15606129 PMID:17562736 paraoxon decreases expression ISO RGD:736447 6480464 Paraoxon results in decreased expression of HSPA5 protein CTD PMID:17223147 paraquat increases expression ISO RGD:2843 6480464 Paraquat results in increased expression of HSPA5 mRNA CTD PMID:17935786 paraquat multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in increased expression of HSPA5 mRNA CTD PMID:18386188 paraquat increases expression ISO RGD:2843 6480464 Paraquat results in increased expression of HSPA5 mRNA CTD PMID:17935786 more ... paraquat increases expression ISO RGD:2843 6480464 Paraquat results in increased expression of HSPA5 mRNA CTD PMID:17935786 PMID:22678742 paraquat increases expression ISO RGD:2843 6480464 Paraquat results in increased expression of HSPA5 protein CTD PMID:22245251 PMID:22678742 paraquat multiple interactions ISO RGD:2843 6480464 NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of HSPA5 mRNA]; more ... CTD PMID:22678742 paraquat increases expression ISO RGD:2843 6480464 Paraquat results in increased expression of HSPA5 protein CTD PMID:22245251 paraquat multiple interactions ISO RGD:2843 6480464 Minocycline inhibits the reaction [Paraquat results in increased expression of HSPA5 protein] CTD PMID:22245251 paraquat multiple interactions ISO RGD:736447 6480464 salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein] CTD PMID:19735704 paraquat increases expression ISO RGD:736447 6480464 Paraquat results in increased expression of HSPA5 protein CTD PMID:19735704 paraquat increases expression ISO RGD:736447 6480464 Paraquat results in increased expression of HSPA5 mRNA CTD PMID:20883675 perfluorodecanoic acid increases metabolic processing ISO RGD:2843 6480464 perfluorodecanoic acid results in increased metabolism of HSPA5 protein CTD PMID:7958552 perfluorodecanoic acid increases phosphorylation ISO RGD:2843 6480464 perfluorodecanoic acid results in increased phosphorylation of HSPA5 protein CTD PMID:7880882 perfluorooctanoic acid decreases expression EXP   6480464 perfluorooctanoic acid results in decreased expression of HSPA5 mRNA CTD PMID:21318169 perfluorooctanoic acid multiple interactions EXP   6480464 PPARA protein affects the reaction [perfluorooctanoic acid results in decreased expression of HSPA5 mRNA] CTD PMID:21318169 phlorizin increases expression EXP   6480464 Phlorhizin results in increased expression of HSPA5 mRNA CTD PMID:22538082 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 deoxynivalenol inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA5 mRNA]; more ... CTD PMID:10652249 pirimicarb increases expression ISO RGD:736447 6480464 pirimicarb results in increased expression of HSPA5 protein CTD PMID:16271832 pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of HSPA5 mRNA CTD PMID:21318169 pirinixic acid multiple interactions EXP   6480464 PPARA protein affects the reaction [pirinixic acid results in decreased expression of HSPA5 mRNA] CTD PMID:21318169 progesterone affects expression EXP   6480464 Progesterone affects the expression of HSPA5 mRNA CTD PMID:17251523 propiconazole increases expression EXP   6480464 propiconazole results in increased expression of HSPA5 mRNA CTD PMID:21278054 quercetin multiple interactions ISO RGD:736447 6480464 Quercetin inhibits the reaction [Calcimycin results in increased expression of HSPA5 mRNA]; more ... CTD PMID:19428936 quercetin decreases expression ISO RGD:736447 6480464 Quercetin results in decreased expression of HSPA5 mRNA CTD PMID:21632981 quercetin affects expression ISO RGD:2843 6480464 Quercetin affects the expression of HSPA5 mRNA CTD PMID:18178720 quercetin increases expression ISO RGD:736447 6480464 Quercetin results in increased expression of HSPA5 protein CTD PMID:15221776 resveratrol decreases expression ISO RGD:736447 6480464 resveratrol results in decreased expression of HSPA5 protein; more ... CTD PMID:20717957 resveratrol multiple interactions EXP   6480464 [resveratrol results in decreased activity of MTOR protein] inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA] CTD PMID:21321189 resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 PMID:18089832 resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 more ... rosiglitazone increases expression ISO RGD:736447 6480464 rosiglitazone results in increased expression of HSPA5 mRNA CTD PMID:15525695 rosiglitazone increases expression ISO RGD:736447 6480464 rosiglitazone results in increased expression of HSPA5 protein CTD PMID:20816668 PMID:15525695 rosiglitazone increases expression ISO RGD:736447 6480464 rosiglitazone results in increased expression of HSPA5 protein CTD PMID:15525695 PMID:20816668 rosiglitazone increases expression ISO RGD:2843 6480464 rosiglitazone results in increased expression of HSPA5 mRNA CTD PMID:20816668 rotenone multiple interactions EXP   6480464 4-phenylbutyric acid inhibits the reaction [Rotenone results in increased expression of HSPA5 protein] CTD PMID:17459145 rotenone increases expression EXP   6480464 Rotenone results in increased expression of HSPA5 protein CTD PMID:17459145 saquinavir increases expression ISO RGD:736447 6480464 Saquinavir results in increased expression of HSPA5 protein CTD PMID:19147209 silicon dioxide increases expression ISO RGD:736447 6480464 Silicon Dioxide analog results in increased expression of HSPA5 mRNA CTD PMID:22245057 silicon dioxide multiple interactions ISO RGD:736447 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased expression of HSPA5 mRNA CTD PMID:22245057 silver atom multiple interactions ISO RGD:736447 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased expression of HSPA5 mRNA CTD PMID:22245057 silver(0) multiple interactions ISO RGD:736447 6480464 [Silicon Dioxide analog co-treated with Silver] results in increased expression of HSPA5 mRNA CTD PMID:22245057 simvastatin increases expression ISO RGD:736447 6480464 Simvastatin results in increased expression of HSPA5 mRNA CTD PMID:18664198 PMID:19253821 simvastatin increases expression ISO RGD:736447 6480464 Simvastatin results in increased expression of HSPA5 mRNA CTD PMID:19253821 PMID:18664198 simvastatin increases expression ISO RGD:736447 6480464 Simvastatin results in increased expression of HSPA5 protein CTD PMID:19253821 streptozocin multiple interactions ISO RGD:2843 6480464 Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein] CTD PMID:19634143 streptozocin decreases expression ISO RGD:2843 6480464 Streptozocin results in decreased expression of HSPA5 protein CTD PMID:19634143 tamoxifen multiple interactions ISO RGD:736447 6480464 Tamoxifen promotes the reaction [Nelfinavir results in increased expression of HSPA5 protein] CTD PMID:20594311 tamoxifen multiple interactions EXP   6480464 Tamoxifen inhibits the reaction [Dietary Fats results in increased expression of HSPA5 protein]; more ... CTD PMID:23038002 tamoxifen increases expression ISO RGD:2843 6480464 Tamoxifen results in increased expression of HSPA5 mRNA CTD PMID:19400957 tamoxifen increases expression EXP   6480464 Tamoxifen results in increased expression of HSPA5 mRNA CTD PMID:19400957 tamoxifen affects expression EXP   6480464 Tamoxifen affects the expression of HSPA5 mRNA CTD PMID:17555576 tamoxifen increases expression ISO RGD:736447 6480464 Tamoxifen results in increased expression of HSPA5 protein CTD PMID:19812351 telmisartan decreases expression ISO RGD:2843 6480464 telmisartan results in decreased expression of HSPA5 protein CTD PMID:19102871 tert-butyl hydroperoxide increases expression ISO RGD:736447 6480464 tert-Butylhydroperoxide results in increased expression of HSPA5 mRNA CTD PMID:12766906 testosterone affects expression EXP   6480464 Testosterone affects the expression of HSPA5 mRNA CTD PMID:17003280 tetrachloromethane affects expression ISO RGD:2843 6480464 Carbon Tetrachloride affects the expression of HSPA5 mRNA CTD PMID:15963342 tetrachloromethane multiple interactions ISO RGD:2843 6480464 [N,N-dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of HSPA5 mRNA; more ... CTD PMID:20097184 thapsigargin multiple interactions ISO RGD:736447 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; more ... CTD PMID:19428936 thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:14610226 more ... thapsigargin multiple interactions EXP   6480464 PTPN1 gene mutant form promotes the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; more ... CTD PMID:22509299 thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17475668 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:14610226 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 CTD PMID:22425709 thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:12198651 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17475668 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:14610226 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:16236328 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:18799549 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:17332266 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:19139269 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17915553 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:19428936 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17915553 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:14610226 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:21692457 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17915553 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17475668 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:18799549 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:21320468 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:17332266 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17416481 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:18799549 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:19141685 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:20626587 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:19428936 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:16338971 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:16338971 PMID:17915553 thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17475668 more ... thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:18799549 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:12198651 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:17332266 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:16236328 more ... thapsigargin increases expression ISO RGD:2843 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:17915553 PMID:16338971 thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17915553 more ... thapsigargin multiple interactions ISO RGD:2843 6480464 Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; more ... CTD PMID:17915553 thapsigargin multiple interactions EXP   6480464 Vaticanol B inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] CTD PMID:17475668 thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:18799549 more ... thapsigargin multiple interactions EXP   6480464 Apigenin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]; more ... CTD PMID:20493918 thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 protein CTD PMID:17416481 more ... thapsigargin increases expression ISO RGD:736447 6480464 Thapsigargin results in increased expression of HSPA5 mRNA CTD PMID:17332266 more ... thapsigargin multiple interactions ISO RGD:736447 6480464 tauroursodeoxycholic acid inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] CTD PMID:12198651 thapsigargin multiple interactions ISO RGD:736447 6480464 Doxorubicin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] CTD PMID:16298333 toluene increases expression ISO RGD:736447 6480464 Toluene results in increased expression of HSPA5 protein CTD PMID:12183065 trans-resveratrol decreases expression ISO RGD:736447 6480464 resveratrol results in decreased expression of HSPA5 protein; more ... CTD PMID:20717957 trans-resveratrol multiple interactions EXP   6480464 [resveratrol results in decreased activity of MTOR protein] inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA] CTD PMID:21321189 trans-resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 PMID:18089832 trans-resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 trans-resveratrol increases expression ISO RGD:736447 6480464 resveratrol results in increased expression of HSPA5 protein CTD PMID:17914584 more ... transplatin decreases expression ISO RGD:736447 6480464 transplatin results in decreased expression of HSPA5 mRNA CTD PMID:11099651 trichloroethene decreases expression EXP   6480464 Trichloroethylene results in decreased expression of HSPA5 mRNA CTD PMID:15363585 troglitazone affects response to substance ISO RGD:736447 6480464 HSPA5 protein affects the susceptibility to troglitazone CTD PMID:15525695 troglitazone increases expression ISO RGD:736447 6480464 troglitazone results in increased expression of HSPA5 mRNA CTD PMID:15525695 PMID:19631733 troglitazone increases expression ISO RGD:736447 6480464 troglitazone results in increased expression of HSPA5 protein CTD PMID:15525695 troglitazone increases expression ISO RGD:736447 6480464 troglitazone results in increased expression of HSPA5 mRNA CTD PMID:19631733 PMID:15525695 tunicamycin multiple interactions ISO RGD:736447 6480464 Quercetin inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA]; more ... CTD PMID:19428936 tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... tunicamycin multiple interactions EXP   6480464 [resveratrol results in decreased activity of MTOR protein] inhibits the reaction [Tunicamycin results in increased expression of HSPA5 mRNA] CTD PMID:21321189 tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:18799549 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... tunicamycin multiple interactions EXP   6480464 PTPN1 gene mutant form promotes the reaction [Tunicamycin results in increased expression of HSPA5 protein] CTD PMID:22509299 tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:18799549 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:19139269 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:12147617 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:18477628 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:18799549 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:20015086 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:21320468 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:19336499 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:19141685 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:19428936 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:21320468 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:20071420 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:19141685 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:19336499 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:15049342 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:21320468 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:17416481 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15019097 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:17416481 more ... tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15049342 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:20015086 more ... tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:20015086 more ... tunicamycin increases expression ISO RGD:2843 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:20071420 more ... tunicamycin multiple interactions ISO RGD:2843 6480464 Nicotine inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein] CTD PMID:18477628 tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 protein CTD PMID:20626587 more ... tunicamycin multiple interactions EXP   6480464 Amiloride inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein]; more ... CTD PMID:20015086 tunicamycin increases expression ISO RGD:736447 6480464 Tunicamycin results in increased expression of HSPA5 mRNA CTD PMID:15049342 more ... tunicamycin multiple interactions ISO RGD:736447 6480464 bortezomib inhibits the reaction [Tunicamycin results in increased expression of HSPA5 protein] CTD PMID:16357177 uranium atom increases expression ISO RGD:736447 6480464 Uranium results in increased expression of HSPA5 mRNA CTD PMID:14971665 valproic acid increases expression ISO RGD:2843 6480464 Valproic Acid results in increased expression of HSPA5 protein CTD PMID:16236328 valproic acid affects expression EXP   6480464 Valproic Acid affects the expression of HSPA5 mRNA CTD PMID:17292431 wortmannin multiple interactions ISO RGD:736447 6480464 wortmannin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA] CTD PMID:19428936 zinc atom multiple interactions ISO RGD:2843 6480464 Zinc inhibits the reaction [lead acetate binds to HSPA5 protein] CTD PMID:10702365 zinc atom multiple interactions ISO RGD:736447 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of HSPA5 mRNA CTD PMID:18593933 zinc pyrithione increases expression ISO RGD:736447 6480464 zinc pyrithione results in increased expression of HSPA5 mRNA CTD PMID:21424779 zinc(0) multiple interactions ISO RGD:2843 6480464 Zinc inhibits the reaction [lead acetate binds to HSPA5 protein] CTD PMID:10702365 zinc(0) multiple interactions ISO RGD:736447 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of HSPA5 mRNA CTD PMID:18593933 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) activation of signaling protein activity involved in unfolded protein response   IMP   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 cellular response to glucose starvation   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 cellular response to interleukin-4   IDA   2290270 MGI:MGI:1859302|PMID:9798653 MGI MGI:MGI:1859302 PMID:9798653 cerebellar Purkinje cell layer development   IMP   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 cerebellum structural organization   IMP   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 ER overload response   IDA   2290270 MGI:MGI:2158984|PMID:11854325 MGI MGI:MGI:2158984 PMID:11854325 negative regulation of apoptotic process   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 negative regulation of transforming growth factor beta receptor signaling pathway   IGI MGI:MGI:98658 2290270 MGI:MGI:3771280|PMID:17991893 MGI MGI:MGI:3771280 PMID:17991893 positive regulation of embryonic development   TAS   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 positive regulation of protein ubiquitination   IMP   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 proteolysis involved in cellular protein catabolic process   IDA   2290270 MGI:MGI:4418606|PMID:18923430 BHF-UCL MGI:MGI:4418606 PMID:18923430 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) cell surface   IDA   2290270 MGI:MGI:3771280|PMID:17991893 MGI MGI:MGI:3771280 PMID:17991893 cell surface   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 cytoplasm   IEA UniProtKB-KW:KW-0963 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 endoplasmic reticulum   ISO UniProtKB:P11021 2290270 MGI:MGI:3611991|PMID:16223484 MGI MGI:MGI:3611991 PMID:16223484 endoplasmic reticulum   IDA   2290270 MGI:MGI:5432418|PMID:22783020 MGI MGI:MGI:5432418 PMID:22783020 endoplasmic reticulum   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 endoplasmic reticulum   IDA   2290270 MGI:MGI:3037530|PMID:14960307 MGI MGI:MGI:3037530 PMID:14960307 endoplasmic reticulum   IDA   2290270 MGI:MGI:2675925|PMID:12826667 MGI MGI:MGI:2675925 PMID:12826667 endoplasmic reticulum   IDA   2290270 MGI:MGI:3640843|PMID:16906134 MGI MGI:MGI:3640843 PMID:16906134 endoplasmic reticulum   IDA   2290270 MGI:MGI:3057045|PMID:15452145 MGI MGI:MGI:3057045 PMID:15452145 endoplasmic reticulum   IDA   2290270 MGI:MGI:2662800|PMID:12646573 MGI MGI:MGI:2662800 PMID:12646573 endoplasmic reticulum   IDA   2290270 MGI:MGI:3054306|PMID:15294975 MGI MGI:MGI:3054306 PMID:15294975 endoplasmic reticulum   IDA   2290270 MGI:MGI:52620|PMID:7679955 MGI MGI:MGI:52620 PMID:7679955 endoplasmic reticulum   ISO UniProtKB:P06761 2290270 MGI:MGI:3848633|PMID:19474315 MGI MGI:MGI:3848633 PMID:19474315 endoplasmic reticulum chaperone complex   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 endoplasmic reticulum lumen   IDA   2290270 MGI:MGI:4437543|PMID:19816510 BHF-UCL MGI:MGI:4437543 PMID:19816510 endoplasmic reticulum-Golgi intermediate compartment   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 integral to endoplasmic reticulum membrane   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 midbody   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 nucleus   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 signalosome colocalizes_with ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) ATP binding   IEA UniProtKB-KW:KW-0067 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 misfolded protein binding   IDA   2290270 MGI:MGI:4418606|PMID:18923430 BHF-UCL MGI:MGI:4418606 PMID:18923430 misfolded protein binding   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 nucleotide binding   IEA UniProtKB-KW:KW-0547 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 protein binding   IPI UniProtKB:Q61712 2290270 MGI:MGI:2181520|PMID:12065409 MGI MGI:MGI:2181520 PMID:12065409 protein binding   IPI UniProtKB:Q91YW3 2290270 MGI:MGI:4418606|PMID:18923430 BHF-UCL MGI:MGI:4418606 PMID:18923430 protein binding   IPI UniProtKB:O75460 2290270 MGI:MGI:3623708|PMID:16645094 IntAct MGI:MGI:3623708 PMID:16645094 protein binding   IPI UniProtKB:P51865 2290270 MGI:MGI:3771280|PMID:17991893 MGI MGI:MGI:3771280 PMID:17991893 protein binding   IPI UniProtKB:O54998 2290270 MGI:MGI:3037530|PMID:14960307 MGI MGI:MGI:3037530 PMID:14960307 protein domain specific binding   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 ribosome binding   IDA   2290270 MGI:MGI:2181520|PMID:12065409 MGI MGI:MGI:2181520 PMID:12065409 ubiquitin protein ligase binding   ISO UniProtKB:P11021 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 unfolded protein binding   ISO RGD:2843 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) antigen processing and presentation pathway   IEA RGD:10742 6907045   KEGG mmu:04612 Endoplasmic Reticulum-associated degradation pathway   IEA RGD:10742 6907045   KEGG mmu:04141 prion diseases pathway   IEA RGD:10742 6907045   KEGG mmu:05020 External Database Links KEGG Pathway Antigen processing and presentation Prion diseases Protein export Protein processing in endoplasmic reticulum Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) abnormal alveolar lamellar body morphology   IAGP   5509061   MGI PMID:17464327 abnormal axon fasiculation   IAGP   5509061   MGI PMID:21214893 abnormal axon fasiculation   IAGP   5509061   MGI PMID:22821687 abnormal axon morphology   IAGP   5509061   MGI PMID:22821687 abnormal axon outgrowth   IAGP   5509061   MGI PMID:21214893 abnormal axon outgrowth   IAGP   5509061   MGI PMID:22821687 abnormal blastocyst morphology   IAGP   5509061   MGI PMID:16847323 abnormal brain internal capsule morphology   IAGP   5509061   MGI PMID:22821687 abnormal brain white matter morphology   IAGP   5509061   MGI PMID:22821687 abnormal cerebellum morphology   IAGP   5509061   MGI PMID:22821687 abnormal cerebral cortex morphology   IAGP   5509061   MGI PMID:21214893 abnormal cerebral cortex morphology   IAGP   5509061   MGI PMID:22821687 abnormal corpus callosum morphology   IAGP   5509061   MGI PMID:22821687 abnormal cortical intermediate zone morphology   IAGP   5509061   MGI PMID:21214893 abnormal cortical intermediate zone morphology   IAGP   5509061   MGI PMID:22821687 abnormal hippocampus morphology   IAGP   5509061   MGI PMID:21214893 abnormal inner cell mass apoptosis   IAGP   5509061   MGI PMID:16847323 abnormal inner cell mass proliferation   IAGP   5509061   MGI PMID:16847323 abnormal neuron differentiation   IAGP   5509061   MGI PMID:22821687 abnormal neuron proliferation   IAGP   5509061   MGI PMID:22821687 abnormal production of surfactant   IAGP   5509061   MGI PMID:17464327 abnormal pulmonary alveolus epithelial cell morphology   IAGP   5509061   MGI PMID:17464327 abnormal renal tubule morphology   IAGP   5509061   MGI PMID:18158912 abnormal stratification in cerebral cortex   IAGP   5509061   MGI PMID:22821687 abnormal surfactant secretion   IAGP   5509061   MGI PMID:17464327 abnormal telencephalon morphology   IAGP   5509061   MGI PMID:21214893 abnormal type II pneumocyte morphology   IAGP   5509061   MGI PMID:17464327 atelectasis   IAGP   5509061   MGI PMID:17464327 cleft palate   IAGP   5509061   MGI PMID:21214893 complete embryonic lethality at implantation   IAGP   5509061   MGI PMID:16847323 complete neonatal lethality   IAGP   5509061   MGI PMID:21214893 complete neonatal lethality   IAGP   5509061   MGI PMID:17464327 complete neonatal lethality   IAGP   5509061   MGI PMID:22821687 cyanosis   IAGP   5509061   MGI PMID:17464327 decreased body size   IAGP   5509061   MGI PMID:22821687 decreased fetal size   IAGP   5509061   MGI PMID:17464327 decreased surfactant secretion   IAGP   5509061   MGI PMID:22821687 dilated renal tubules   IAGP   5509061   MGI PMID:18158912 failure to hatch from the zona pellucida   IAGP   5509061   MGI PMID:16847323 forebrain hypoplasia   IAGP   5509061   MGI PMID:22821687 hematoma   IAGP   5509061   MGI PMID:21214893 increased susceptibility to injury   IAGP   5509061   MGI PMID:18158912 no abnormal phenotype detected   IAGP   5509061   MGI PMID:16847323 pallor   IAGP   5509061   MGI PMID:17464327 prostate gland adenocarcinoma   IAGP   5509061   MGI PMID:19033462 prostate intraepithelial neoplasia   IAGP   5509061   MGI PMID:19033462 pulmonary alveolar hemorrhage   IAGP   5509061   MGI PMID:17464327 renal interstitial fibrosis   IAGP   5509061   MGI PMID:18158912 renal tubule atrophy   IAGP   5509061   MGI PMID:18158912 respiratory distress   IAGP   5509061   MGI PMID:21214893 respiratory distress   IAGP   5509061   MGI PMID:17464327 respiratory failure   IAGP   5509061   MGI PMID:22821687 small kidney   IAGP   5509061   MGI PMID:21214893 small olfactory bulb   IAGP   5509061   MGI PMID:21214893 Disease Annotations Arthritis, Rheumatoid  (ISS) Autoimmune Diseases  (ISS) Breast Neoplasms  (IEP) Dopamine beta hydroxylase deficiency  (ISS) Glioma  (ISS) Infertility, Female  (ISS) Inflammatory Bowel Diseases  (ISS) Nerve Degeneration  (ISS) Neuronal Ceroid-Lipofuscinoses  (IEP) Peripheral Nerve Injuries  (ISS) Pulmonary Fibrosis  (IEP) Reperfusion Injury  (ISS) Spinal Cord Injuries  (IEP) Gene-Chemical Interaction Annotations (R)-adrenaline  (ISO) (R)-noradrenaline  (ISO) (S)-nicotine  (ISO) 1,3-dinitrobenzene  (ISO) 1,4-dithiothreitol  (ISO) 17alpha-ethynylestradiol  (EXP,ISO) 17beta-estradiol  (EXP,ISO) 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO) 1H-pyrazole  (EXP) 2,2,2-tetramine  (ISO) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2,4,6-trinitrotoluene  (ISO) 2,4-dinitrotoluene  (ISO) 2-amino-2-deoxy-D-glucopyranose  (EXP,ISO) 2-deoxy-D-glucose  (ISO) 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO) 3H-1,2-dithiole-3-thione  (EXP,ISO) 4-hydroxynon-2-enal  (ISO) 4-hydroxyphenyl retinamide  (ISO) 4-phenylbutyric acid  (EXP,ISO) 7,12-dimethyltetraphene  (ISO) 7H-xanthine  (ISO) 8-bromo-3',5'-cyclic AMP  (ISO) 9H-xanthine  (ISO) acetylsalicylic acid  (ISO) acrolein  (ISO) actinomycin D  (ISO) aflatoxin B1  (EXP) aldehydo-D-glucosamine  (EXP,ISO) all-trans-retinoic acid  (EXP,ISO) amiloride  (EXP) ammonium chloride  (ISO) aniline  (ISO) antimycin A  (ISO) apigenin  (EXP) aristolochic acid  (ISO) arsenic atom  (EXP,ISO) arsenite(3-)  (EXP,ISO) atrazine  (ISO) benzene  (ISO) benzo[a]pyrene  (EXP,ISO) beta-D-glucosamine  (EXP,ISO) bifenthrin  (ISO) bilirubin  (ISO) bis(2-chloroethyl) sulfide  (EXP) bis(2-ethylhexyl) phthalate  (EXP,ISO) bisphenol A  (EXP,ISO) brefeldin A  (EXP,ISO) bromobenzene  (ISO) bupropion  (ISO) cadmium atom  (ISO) cadmium dichloride  (EXP,ISO) cadmium sulfate  (ISO) capsaicin  (ISO) carbaryl  (ISO) carboplatin  (ISO) celastrol  (ISO) celecoxib  (ISO) chlordecone  (EXP) chlorhexidine  (EXP) chlorobenzene  (ISO) chloropicrin  (ISO) chlorpyrifos  (EXP) choline  (EXP,ISO) chrysazin  (ISO) cisplatin  (EXP,ISO) clofibrate  (EXP,ISO) cobalt dichloride  (ISO) cocaine  (ISO) copper atom  (ISO) copper(0)  (ISO) copper(2+) sulfate  (ISO) copper(II) chloride  (ISO) curcumin  (EXP) cycloheximide  (ISO) cyclophosphamide  (ISO) cyclosporin A  (EXP,ISO) D-glucose  (EXP,ISO) D-mannopyranose  (ISO) D-penicillamine  (ISO) DDT  (ISO) Delta(9)-tetrahydrocannabinol  (ISO) deoxycholic acid  (ISO) diamminedichloroplatinum  (ISO) diarsenic trioxide  (EXP,ISO) diazinon  (EXP) diazoxide  (EXP) dichlorine  (ISO) dicoumarol  (ISO) diethyl maleate  (EXP) dihydrocapsaicin  (ISO) diisopropyl fluorophosphate  (ISO) dimethylarsinic acid  (ISO) dioxygen  (ISO) diuron  (ISO) doxorubicin  (ISO) endosulfan  (ISO) ethanol  (EXP) ethylbenzene  (ISO) folic acid  (EXP) formetanate  (ISO) fructose  (EXP) fulvestrant  (EXP) furan  (ISO) gadolinium trichloride  (ISO) galactose  (ISO) gedunin  (ISO) geldanamycin  (ISO) glucose  (EXP,ISO) glutathione  (EXP) graphite  (ISO) hyaluronic acid  (ISO) hydrazine  (ISO) hydrogen peroxide  (ISO) imidacloprid  (ISO) indomethacin  (EXP,ISO) ionomycin  (EXP) iprodione  (ISO) isoprenaline  (EXP) ketamine  (ISO) kojic acid  (ISO) L-ascorbic acid  (ISO) L-methionine  (EXP) lactacystin  (ISO) lanthanum atom  (ISO) lead diacetate  (ISO) lead(0)  (ISO) lithium atom  (ISO) LY294002  (ISO) maneb  (EXP) manganese atom  (ISO) manganese(0)  (ISO) meglumine amidotrizoate  (ISO) melatonin  (ISO) menadione  (ISO) mercury atom  (ISO) mercury dichloride  (ISO) mercury(0)  (ISO) methamphetamine  (ISO) methapyrilene  (ISO) methomyl  (ISO) metyrapone  (ISO) minocycline  (ISO) N,N-dimethylformamide  (ISO) N-acetyl-L-cysteine  (EXP,ISO) N-methyl-4-phenylpyridinium  (ISO) N-nitrosodiethylamine  (ISO) naphthalene  (EXP) nickel atom  (ISO) nifedipine  (ISO) nitric oxide  (ISO) ochratoxin A  (EXP,ISO) ozone  (EXP,ISO) paracetamol  (EXP) paraoxon  (ISO) paraquat  (EXP,ISO) perfluorodecanoic acid  (ISO) perfluorooctanoic acid  (EXP) phlorizin  (EXP) phorbol 13-acetate 12-myristate  (EXP) pirimicarb  (ISO) pirinixic acid  (EXP) progesterone  (EXP) propiconazole  (EXP) quercetin  (ISO) resveratrol  (EXP,ISO) rosiglitazone  (ISO) rotenone  (EXP) saquinavir  (ISO) silicon dioxide  (ISO) silver atom  (ISO) silver(0)  (ISO) simvastatin  (ISO) streptozocin  (ISO) tamoxifen  (EXP,ISO) telmisartan  (ISO) tert-butyl hydroperoxide  (ISO) testosterone  (EXP) tetrachloromethane  (ISO) thapsigargin  (EXP,ISO) toluene  (ISO) trans-resveratrol  (EXP,ISO) transplatin  (ISO) trichloroethene  (EXP) troglitazone  (ISO) tunicamycin  (EXP,ISO) uranium atom  (ISO) valproic acid  (EXP,ISO) wortmannin  (ISO) zinc atom  (ISO) zinc pyrithione  (ISO) zinc(0)  (ISO) Gene Ontology Annotations Biological Process activation of signaling protein activity involved in unfolded protein response  (IMP) cellular response to glucose starvation  (ISO) cellular response to interleukin-4  (IDA) cerebellar Purkinje cell layer development  (IMP) cerebellum structural organization  (IMP) ER overload response  (IDA) negative regulation of apoptotic process  (ISO) negative regulation of transforming growth factor beta receptor signaling pathway  (IGI) positive regulation of embryonic development  (TAS) positive regulation of protein ubiquitination  (IMP) proteolysis involved in cellular protein catabolic process  (IDA) Cellular Component cell surface  (IDA,ISO) cytoplasm  (IEA) endoplasmic reticulum  (IDA,ISO) endoplasmic reticulum chaperone complex  (ISO) endoplasmic reticulum lumen  (IDA) endoplasmic reticulum-Golgi intermediate compartment  (ISO) integral to endoplasmic reticulum membrane  (ISO) midbody  (ISO) nucleus  (ISO) signalosome  (ISO) Molecular Function ATP binding  (IEA) misfolded protein binding  (IDA,ISO) nucleotide binding  (IEA) protein binding  (IPI) protein domain specific binding  (ISO) ribosome binding  (IDA) ubiquitin protein ligase binding  (ISO) unfolded protein binding  (ISO) Molecular Pathway Annotations antigen processing and presentation pathway  (IEA) Endoplasmic Reticulum-associated degradation pathway  (IEA) prion diseases pathway  (IEA) External Database Links KEGG Pathway Antigen processing and presentation Prion diseases Protein export Protein processing in endoplasmic reticulum Phenotype Annotations abnormal alveolar lamellar body morphology  (IAGP) abnormal axon fasiculation  (IAGP) abnormal axon morphology  (IAGP) abnormal axon outgrowth  (IAGP) abnormal blastocyst morphology  (IAGP) abnormal brain internal capsule morphology  (IAGP) abnormal brain white matter morphology  (IAGP) abnormal cerebellum morphology  (IAGP) abnormal cerebral cortex morphology  (IAGP) abnormal corpus callosum morphology  (IAGP) abnormal cortical intermediate zone morphology  (IAGP) abnormal hippocampus morphology  (IAGP) abnormal inner cell mass apoptosis  (IAGP) abnormal inner cell mass proliferation  (IAGP) abnormal neuron differentiation  (IAGP) abnormal neuron proliferation  (IAGP) abnormal production of surfactant  (IAGP) abnormal pulmonary alveolus epithelial cell morphology  (IAGP) abnormal renal tubule morphology  (IAGP) abnormal stratification in cerebral cortex  (IAGP) abnormal surfactant secretion  (IAGP) abnormal telencephalon morphology  (IAGP) abnormal type II pneumocyte morphology  (IAGP) atelectasis  (IAGP) cleft palate  (IAGP) complete embryonic lethality at implantation  (IAGP) complete neonatal lethality  (IAGP) cyanosis  (IAGP) decreased body size  (IAGP) decreased fetal size  (IAGP) decreased surfactant secretion  (IAGP) dilated renal tubules  (IAGP) failure to hatch from the zona pellucida  (IAGP) forebrain hypoplasia  (IAGP) hematoma  (IAGP) increased susceptibility to injury  (IAGP) no abnormal phenotype detected  (IAGP) pallor  (IAGP) prostate gland adenocarcinoma  (IAGP) prostate intraepithelial neoplasia  (IAGP) pulmonary alveolar hemorrhage  (IAGP) renal interstitial fibrosis  (IAGP) renal tubule atrophy  (IAGP) respiratory distress  (IAGP) respiratory failure  (IAGP) small kidney  (IAGP) small olfactory bulb  (IAGP) References - curated 1. Blass S, etal., Arthritis Rheum. 2001 Apr;44(4):761-71. 2. Croci S, etal., Proteomics. 2010 Nov;10(21):3835-53. 3. Deuring JJ, etal., Biochem J. 2012 Jan 1;441(1):87-93. 4. Galizzi G, etal., Neurosci Lett. 2011 Jan 25;488(3):258-62. Epub 2010 Nov 19. 5. Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90. 6. Kim CH, etal., J Biol Chem. 2011 Mar 18;286(11):9196-204. Epub 2011 Jan 5. 7. Ko MS, etal., Development 2000 Apr;127(8):1737-49. 8. Ko MS, etal., Hum Mol Genet 1998 Nov;7(12):1967-78. 9. Mande PV, etal., Reproduction. 2011 Dec 5. 10. Mantuano E, etal., J Neurosci. 2011 Sep 21;31(38):13376-85. 11. MGD and Homologene mouse data transfer 12. MGD data from the GO Consortium 13. Ohri SS, etal., J Neurotrauma. 2011 Nov 21. 14. Okazaki Y, etal., Nature 2002 Dec 5;420(6915):563-73. 15. Penas C, etal., Cell Death Differ. 2011 Oct;18(10):1617-27. doi: 10.1038/cdd.2011.24. Epub 2011 Mar 25. 16. Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology 17. RGD automated import pipeline 18. RGD automated import pipeline for gene-chemical interactions 19. Srinivasan K and Sharma SS, Life Sci. 2012 Jan 16;90(3-4):154-60. Epub 2011 Oct 29. 20. Sukumaran V, etal., Int J Biol Sci. 2011;7(8):1077-92. Epub 2011 Sep 8. 21. Torres-Gonzalez E, etal., Am J Respir Cell Mol Biol. 2012 Jan 6. 22. Zhang LH, etal., Brain Res. 2011 Jan 31;1371:23-31. Epub 2010 Nov 25. References - uncurated PubMed 10349636   10700579   10777498   10922068   10926097   10952971   11042159   11076861   11331305   11687283   11835228   11836248   11854325   12054809   12065409   12110171   12194978   12200422   12446677   12475965   12477932   12520002   12535952   12617806   12646573   12818208   12826667   12871976   12904583   1362103   1450517   14607830   14610273   14960307   15064947   15146195   15157672   15226823   15294975   15452145   15459690   15489334   15525676   15527976   15664986   15677452   15699139   15745951   15782199   15836626   15845644   15947236   15952741   15980866   16081825   16131858   16141072   16141073   16196101   16223484   16271702   16282978   16314518   16343492   16376939   16452489   16574737   16601230   16602821   16645094   16707115   16800626   16847323   16906134   1692794   16959763   17024087   17090218   17110338   17141632   17223077   17309103   17399692   17425118   17464327   17640991   17689130   17890727   17913437   17954555   17991893   17996725   18001291   18083346   18158912   18182158   18199545   18213612   18228200   18385319   18434328   18457657   18554416   18556570   18556704   18579727   18584871   18597185   18614564   18776938   18923430   19033462   19129515   19136429   19139267   19171884   19188447   19352619   19363290   19473344   19474315   19633360   19767744   19805157   19805353   19808260   19808896   19816510   19858219   19955657   20019329   20042652   20089971   20178780   20197277   20416295   20501674   20520781   20637498   20664993   20945367   20971738   21044701   21145001   21214893   21239500   21267068   21310900   21339366   21467168   21503947   21517144   21527244   21565611   21768092   21795745   21797942   21937694   21966382   21982233   22120956   22154935   22155243   22177958   22212133   22230548   22430489   22490889   22495669   22527697   22573382   22589549   22723926   22745161   22753943   22768244   22783020   22821687   22837305   22851173   22869598   22925884   23123197   23180827   2559088   2583523   2766928   2895472   3185564   3623104   6457647   7490102   7523108   7607546   7671812   7679955   7724523   7774911   7829063   7988674   8075499   8088777   8486356   8570653   8631027   8645260   8747926   8799160   9278556   9798653 RGD Disease Portals Hspa5 has been annotated in the following RGD Disease Portals. Biological Process Cancer Diseases Cancer Pathways Cancer Phenotypes Cardiovascular Diseases Cardiovascular Pathways Cardiovascular Phenotypes Diabetes Diseases Diabetes Pathways Immune and Inflammatory Diseases Immune and Inflammatory Pathways Biological Process Neurological Diseases Neurological Pathways Neurological Phenotypes Obesity Diseases Respiratory Diseases Respiratory Pathways Respiratory Phenotypes Genomics Comparative Map Data Hspa5   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,772,090 - 34,776,529 + NCBI Mouse cM Map 2 22.94   NCBI Mouse Celera Assembly 2 34,472,567 - 34,477,006 + NCBI Mouse Genome Assembly Build 37 2 34,627,610 - 34,632,049 + NCBI Mouse Genome Assembly Build 36.1 2 34,627,615 - 34,631,977 + NCBI Mouse Cytogenetic Map 2 B   NCBI HSPA5   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 9 128,009,306 - 128,015,846 - NCBI Human Genome Assembly HuRef 9 97,609,713 - 97,616,253 - NCBI Human Genome Assembly GRCh37 9 127,997,127 - 128,003,666 - NCBI Human Genome Assembly Build 36 9 127,036,953 - 127,043,430 - NCBI Human Cytogenetic Map 9 q33.3   NCBI Human Genome Assembly 9 125,076,687 - 125,083,163   NCBI Hspa5   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 3 p11   NCBI RGSC Genome Assembly v5.0 3 19,157,874 - 19,162,333 + NCBI RGSC Genome Assembly v3.4 3 13,783,825 - 13,788,022 + NCBI Rat Celera Assembly 3 12,776,654 - 12,781,113 + NCBI Genome Assembly 3.1 3 13,680,196 - 13,684,394 + NCBI RH 3.4 3 151.7   RGD Position Markers RH125368   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,775,726 - 34,775,998   UniSTS Mouse cM Map 2 22.5   UniSTS Mouse Celera Assembly 2 34,476,203 - 34,476,475   UniSTS Mouse Genome Assembly Build 37 2 34,631,246 - 34,631,518   UniSTS Mouse Cytogenetic Map 2 B   UniSTS RH94472   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,776,280 - 34,776,438   UniSTS Mouse cM Map 2 22.5   UniSTS Mouse Celera Assembly 2 34,476,757 - 34,476,915   UniSTS Mouse Genome Assembly Build 37 2 34,631,800 - 34,631,958   UniSTS Mouse Cytogenetic Map 2 B   UniSTS Hspa5   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,776,234 - 34,776,367   UniSTS Mouse cM Map 2 22.5   UniSTS Mouse Celera Assembly 2 34,476,711 - 34,476,844   UniSTS Mouse Genome Assembly Build 37 2 34,631,754 - 34,631,887   UniSTS Mouse Cytogenetic Map 2 B   UniSTS D2Wsu141e   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,776,248 - 34,776,457   UniSTS Mouse cM Map 2 23.0   UniSTS Mouse cM Map 2 22.5   UniSTS Mouse Celera Assembly 2 34,476,725 - 34,476,934   UniSTS Mouse Genome Assembly Build 37 2 34,631,768 - 34,631,977   UniSTS Mouse Cytogenetic Map 2 B   UniSTS D2Wsu17e   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,776,220 - 34,776,425   UniSTS Mouse cM Map 2 24.0   UniSTS Mouse cM Map 2 22.5   UniSTS Mouse Celera Assembly 2 34,476,697 - 34,476,902   UniSTS Mouse Genome Assembly Build 37 2 34,631,740 - 34,631,945   UniSTS Mouse Cytogenetic Map 2 B   UniSTS Hspa5   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,775,763 - 34,775,993   UniSTS Mouse Celera Assembly 2 34,476,240 - 34,476,470   UniSTS Mouse Genome Assembly Build 37 2 34,631,283 - 34,631,513   UniSTS Mouse Cytogenetic Map 2 B   UniSTS Hspa5   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,772,729 - 34,773,269   UniSTS Mouse Celera Assembly 2 34,473,206 - 34,473,746   UniSTS Mouse Genome Assembly Build 37 2 34,628,249 - 34,628,789   UniSTS Mouse Cytogenetic Map 2 B   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 1301831 Abhr2_m antigen-induced bronchial hyperresponsiveness 2 (mouse) Not determined 2 33976570 48531511 Mouse 4141854 T2dm2sa_m type 2 diabetes mellitus 2 in SMXA RI mice (mouse) Not determined 2 29273455 148358750 Mouse 1558737 Vacq4_m voluntary alcohol consumption QTL 4 (mouse) Not determined 2 28193636 62193771 Mouse 4142130 Pgis2_m proteoglycan induced spondylitis 2 (mouse) Not determined 2 25273559 56934210 Mouse 4141891 Bmgr2_m bone marrow graft rejection 2 (mouse) Not determined 2 23851001 57851123 Mouse 1357549 Manln2_m mandible length 2 (mouse) Not determined 2 23654659 57654777 Mouse 4142186 Cafcnq1_m cobblestone area-forming cell number QTL 1 (mouse) Not determined 2 23654653 57654777 Mouse 1301376 Etohc1_m ethanol consumption 1 (mouse) Not determined 2 21095233 55095379 Mouse 1301117 Fecq1_m fecundity QTL 1 (mouse) Not determined 2 21095233 55095379 Mouse 1301897 Scc2_m colon tumor susceptibility 2 (mouse) Not determined 2 18384619 52384763 Mouse 1301156 Lbm1_m lean body mass 1 (mouse) Not determined 2 16488530 50488680 Mouse 4141971 Plast2a_m plasma plant sterol 2a (mouse) Not determined 2 14180075 48180221 Mouse 1302009 Sbmd1_m spinal bone mineral density 1 (mouse) Not determined 2 14180075 48180221 Mouse 1301641 Sbmd2_m spinal bone mineral density 2 (mouse) Not determined 2 14180075 48180221 Mouse 4141031 Pltq1_m platelet quantitative locus 1 (mouse) Not determined 2 14180075 48180221 Mouse 1300624 Insq7_m insulin QTL 7 (mouse) Not determined 2 9349954 43350083 Mouse 1302169 Ptz1b_m pentylenetetrazol induced seizure susceptibility 1b (mouse) Not determined 2 8905794 42905916 Mouse 4142037 Etax3_m ethanol induced ataxia 3 (mouse) Not determined 2 8273559 42273748 Mouse 1301790 Pcfm1_m periosteal circumference and femur length 1 (mouse) Not determined 2 8201804 42201904 Mouse 1301980 Fcsa5_m femoral cross-sectional area 5 (mouse) Not determined 2 7644623 41644769 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_001163434 (Get FASTA) Search GEO for Microarray Profiles   NM_022310 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AAHY01015220 (Get FASTA) Search GEO for Microarray Profiles   AJ002387 (Get FASTA) Search GEO for Microarray Profiles   AK004578 (Get FASTA) Search GEO for Microarray Profiles   AK076079 (Get FASTA) Search GEO for Microarray Profiles   AK077463 (Get FASTA) Search GEO for Microarray Profiles   AK144650 (Get FASTA) Search GEO for Microarray Profiles   AK144742 (Get FASTA) Search GEO for Microarray Profiles   AK146647 (Get FASTA) Search GEO for Microarray Profiles   AK148539 (Get FASTA) Search GEO for Microarray Profiles   AK149447 (Get FASTA) Search GEO for Microarray Profiles   AK151244 (Get FASTA) Search GEO for Microarray Profiles   AK151647 (Get FASTA) Search GEO for Microarray Profiles   AK151806 (Get FASTA) Search GEO for Microarray Profiles   AK152020 (Get FASTA) Search GEO for Microarray Profiles   AK152521 (Get FASTA) Search GEO for Microarray Profiles   AK152958 (Get FASTA) Search GEO for Microarray Profiles   AK159719 (Get FASTA) Search GEO for Microarray Profiles   AK160592 (Get FASTA) Search GEO for Microarray Profiles   AK160821 (Get FASTA) Search GEO for Microarray Profiles   AK166207 (Get FASTA) Search GEO for Microarray Profiles   AK166739 (Get FASTA) Search GEO for Microarray Profiles   AK167011 (Get FASTA) Search GEO for Microarray Profiles   AK168012 (Get FASTA) Search GEO for Microarray Profiles   AK168230 (Get FASTA) Search GEO for Microarray Profiles   AK169034 (Get FASTA) Search GEO for Microarray Profiles   AK180947 (Get FASTA) Search GEO for Microarray Profiles   AK181293 (Get FASTA) Search GEO for Microarray Profiles   AK185871 (Get FASTA) Search GEO for Microarray Profiles   AK186478 (Get FASTA) Search GEO for Microarray Profiles   AK188133 (Get FASTA) Search GEO for Microarray Profiles   AK192310 (Get FASTA) Search GEO for Microarray Profiles   AK192496 (Get FASTA) Search GEO for Microarray Profiles   AK194376 (Get FASTA) Search GEO for Microarray Profiles   AK195133 (Get FASTA) Search GEO for Microarray Profiles   AK196010 (Get FASTA) Search GEO for Microarray Profiles   AK197130 (Get FASTA) Search GEO for Microarray Profiles   AK197258 (Get FASTA) Search GEO for Microarray Profiles   AK197968 (Get FASTA) Search GEO for Microarray Profiles   AK198470 (Get FASTA) Search GEO for Microarray Profiles   AK198632 (Get FASTA) Search GEO for Microarray Profiles   AK198934 (Get FASTA) Search GEO for Microarray Profiles   AK200033 (Get FASTA) Search GEO for Microarray Profiles   AK203208 (Get FASTA) Search GEO for Microarray Profiles   AK204292 (Get FASTA) Search GEO for Microarray Profiles   AK206130 (Get FASTA) Search GEO for Microarray Profiles   AK206500 (Get FASTA) Search GEO for Microarray Profiles   AK206677 (Get FASTA) Search GEO for Microarray Profiles   AK206732 (Get FASTA) Search GEO for Microarray Profiles   AK207319 (Get FASTA) Search GEO for Microarray Profiles   AK207523 (Get FASTA) Search GEO for Microarray Profiles   AK207843 (Get FASTA) Search GEO for Microarray Profiles   AK208906 (Get FASTA) Search GEO for Microarray Profiles   AK209206 (Get FASTA) Search GEO for Microarray Profiles   AK212207 (Get FASTA) Search GEO for Microarray Profiles   AK213049 (Get FASTA) Search GEO for Microarray Profiles   AK213790 (Get FASTA) Search GEO for Microarray Profiles   AK214147 (Get FASTA) Search GEO for Microarray Profiles   AK215158 (Get FASTA) Search GEO for Microarray Profiles   AK215673 (Get FASTA) Search GEO for Microarray Profiles   AK216390 (Get FASTA) Search GEO for Microarray Profiles   AK218616 (Get FASTA) Search GEO for Microarray Profiles   AK219238 (Get FASTA) Search GEO for Microarray Profiles   AK219322 (Get FASTA) Search GEO for Microarray Profiles   AL929106 (Get FASTA) Search GEO for Microarray Profiles   BC005785 (Get FASTA) Search GEO for Microarray Profiles   BC050927 (Get FASTA) Search GEO for Microarray Profiles   CH466542 (Get FASTA) Search GEO for Microarray Profiles   D78645 (Get FASTA) Search GEO for Microarray Profiles   M19351 (Get FASTA) Search GEO for Microarray Profiles   M30779 (Get FASTA) Search GEO for Microarray Profiles   U16277 (Get FASTA) Search GEO for Microarray Profiles   U89425 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_022310 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_071705 Peptide Label: precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,772,090 - 34,776,529 + ENTREZGENE Mouse cM Map 2   + ENTREZGENE Mouse Celera Assembly 2 34,472,567 - 34,477,006 + RGD Mouse Genome Assembly Build 37 2 34,627,610 - 34,632,049 + RGD RefSeq Acc Id: NM_001163434 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_001156906 Peptide Label: precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 2 34,772,090 - 34,776,529 + ENTREZGENE Mouse cM Map 2   + ENTREZGENE Mouse Celera Assembly 2 34,472,567 - 34,477,006 + RGD Mouse Genome Assembly Build 37 2 34,627,610 - 34,632,049 + RGD Protein Sequences Protein RefSeqs NP_001156906 (Get FASTA)   NP_071705 (Get FASTA) GenBank Protein AAA37315 (Get FASTA)   AAA37742 (Get FASTA)   AAA76734 (Get FASTA)   AAC36531 (Get FASTA)   AAH50927 (Get FASTA)   BAA11462 (Get FASTA)   BAB23387 (Get FASTA)   BAC36166 (Get FASTA)   BAE27328 (Get FASTA)   BAE28609 (Get FASTA)   BAE28883 (Get FASTA)   BAE30576 (Get FASTA)   BAE30705 (Get FASTA)   BAE30882 (Get FASTA)   BAE31281 (Get FASTA)   BAE31621 (Get FASTA)   BAE35314 (Get FASTA)   BAE35899 (Get FASTA)   BAE38982 (Get FASTA)   BAE39187 (Get FASTA)   BAE39999 (Get FASTA)   BAE40825 (Get FASTA)   CAA05361 (Get FASTA)   EDL08616 (Get FASTA)   EDL08617 (Get FASTA)   EDL08618 (Get FASTA)   P20029 (Get FASTA) Promoters RGD ID: 6831599 Promoter ID: MM_KWN:28838 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen Transcripts: ENSMUST00000100171,   OTTMUST00000028495,   OTTMUST00000028496,   OTTMUST00000028497,   OTTMUST00000028498,   OTTMUST00000028499,   OTTMUST00000028500 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 2 34,627,166 - 34,629,442 + MPROMDB RGD ID: 6874598 Promoter ID: EPDNEW_M750 Type: preliminary Name: Hspa5_1 Description: heat shock protein 5 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 2 34,627,614 - 34,627,674   EPDNEW RGD ID: 6831602 Promoter ID: MM_KWN:28839 Type: Non-CpG SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6 Transcripts: OTTMUST00000028501 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 2 34,629,521 - 34,630,732 + MPROMDB Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000026864 ENTREZGENE Ensembl Protein ENSMUSP00000028222 ENTREZGENE   ENSMUSP00000097747 ENTREZGENE Ensembl Transcript ENSMUST00000028222 ENTREZGENE   ENSMUST00000100171 ENTREZGENE Entrez Gene 14828 ENTREZGENE Germonline ENSMUSG00000026864 HomoloGene Group ID 3908 ENTREZGENE InterPro Heat_shock_70_CS UniProtKB/Swiss-Prot   Hsp_70 UniProtKB/Swiss-Prot KEGG Report mmu:14828 ENTREZGENE, UniProtKB/Swiss-Prot MGD MGI:95835 ENTREZGENE Pfam HSP70 UniProtKB/Swiss-Prot PRINTS HEATSHOCK70 UniProtKB/Swiss-Prot PROSITE ER_TARGET UniProtKB/Swiss-Prot   HSP70_1 UniProtKB/Swiss-Prot   HSP70_2 UniProtKB/Swiss-Prot   HSP70_3 UniProtKB/Swiss-Prot UniGene Mm.330160 ENTREZGENE UniProt GRP78_MOUSE UniProtKB/Swiss-Prot   Q3TI47_MOUSE UniProtKB/TrEMBL   Q3TKF8_MOUSE UniProtKB/TrEMBL   Q3TUS2_MOUSE UniProtKB/TrEMBL   Q3TWF2_MOUSE UniProtKB/TrEMBL   Q3U6V3_MOUSE UniProtKB/TrEMBL   Q3U7T8_MOUSE UniProtKB/TrEMBL   Q3U9G2_MOUSE UniProtKB/TrEMBL   Q3UEM8_MOUSE UniProtKB/TrEMBL   Q9DC41_MOUSE UniProtKB/TrEMBL

More on Hspa5 Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 10742 Created: 2000-05-25 Species: Mus musculus Last Modified: 2013-04-30 Status: ACTIVE