Gclc (glutamate-cysteine ligase, catalytic subunit)

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Keyword

Gene: Gclc (glutamate-cysteine ligase, catalytic subunit) Mus musculus

Symbol:

Gclc

Name:

glutamate-cysteine ligase, catalytic subunit

Description:

ENCODES a protein that exhibits glutamate-cysteine ligase activity; protein heterodimerization activity; ADP binding (ortholog); INVOLVED IN glutathione biosynthetic process; glutathione metabolic process; L-ascorbic acid metabolic process; PARTICIPATES IN glutathione metabolic pathway; ASSOCIATED WITH abnormal embryogenesis/ development; abnormal embryonic-extraembryonic boundary morphology; abnormal liver physiology; ASSOCIATED WITH Amino Acid Metabolism, Inborn Errors (ortholog); Anemia, Hemolytic (ortholog); Cystic Fibrosis (ortholog); FOUND IN cytosol; glutamate-cysteine ligase complex; INTERACTS WITH (2,4,5-trichlorophenoxy)acetic acid; (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

D9Wsu168e; gamma GCS-HS; gamma-ECS; gamma-glutamylcysteine synthetase heavy subunit; GCS heavy chain; Ggcs-hs; GLCL-H; Glclc; glutamate cysteine ligase (gamma-glutamylcysteine synthetase), catalytic; glutamate--cysteine ligase catalytic subunit; OTTMUSP00000023141

Orthologs:

Homo sapiens : GCLC (glutamate-cysteine ligase, catalytic subunit) HGNC
Rattus norvegicus : Gclc (glutamate-cysteine ligase, catalytic subunit)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	9	77,754,535 - 77,794,489	+	NCBI
Mouse cM Map	9	43.36		NCBI
Mouse Celera Assembly	9	74,927,562 - 74,967,526	+	NCBI
Mouse Genome Assembly Build 37	9	77,602,617 - 77,641,458	+	NCBI
Mouse Genome Assembly Build 36.1	9	77,602,617 - 77,641,458	+	NCBI
Mouse Cytogenetic Map	9	D-E		NCBI