Xbp1 (X-box binding protein 1) - Rat Genome Database

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Gene: Xbp1 (X-box binding protein 1) Mus musculus
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Symbol: Xbp1
Name: X-box binding protein 1
RGD ID: 1332312
MGI Page MGI
Description: Enables several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; enzyme binding activity; and phosphatidylinositol 3-kinase regulatory subunit binding activity. Involved in several processes, including cellular response to hexose stimulus; cholesterol homeostasis; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within cellular response to leukemia inhibitory factor; epithelial cell maturation; and exocrine pancreas development. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeletal system. Used to study inflammatory bowel disease. Orthologous to human XBP1 (X-box binding protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: D11Ertd39; D11Ertd39e; tax-responsive element-binding protein 5 homolog; TREB; TREB-; TREB-5; TREB5; X-box-binding protein 1; XBP-; XBP-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,470,641 - 5,475,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,470,659 - 5,475,893 (+)EnsemblGRCm39 Ensembl
GRCm38115,520,641 - 5,525,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,520,659 - 5,525,893 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,420,970 - 5,425,875 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,420,970 - 5,425,875 (+)NCBIMGSCv36mm8
Celera116,013,954 - 6,018,865 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.61NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(-)-anisomycin  (EXP)
(R)-noradrenaline  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-nicotine  (ISO)
1,4-dithiothreitol  (ISO)
1-[2-(3,4-dichlorophenyl)ethyl]-4-methylpiperazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dichlorophenol  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3-acetyldeoxynivalenol  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-aminophenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitrophenol  (EXP)
4-phenylbutyric acid  (EXP,ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
8-Br-cAMP  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
Aloe emodin  (ISO)
alpha-pinene  (ISO)
aluminium atom  (EXP)
aluminium sulfate (anhydrous)  (EXP)
aluminium(0)  (EXP)
AM-251  (ISO)
amiloride  (EXP)
amiodarone  (EXP,ISO)
ammonium chloride  (ISO)
amosite asbestos  (ISO)
antimony trichloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenic trichloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (EXP,ISO)
benzalkonium chloride  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (EXP)
benzoates  (ISO)
beta-D-glucosamine  (EXP,ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bilirubin IXalpha  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
boric acid  (ISO)
bortezomib  (ISO)
brefeldin A  (ISO)
bromobenzene  (ISO)
bupropion  (ISO)
busulfan  (ISO)
butan-1-ol  (ISO)
butanal  (ISO)
Butylparaben  (EXP)
C.I. Natural Red 20  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
Calcimycin  (ISO)
cannabidiol  (EXP,ISO)
captan  (EXP)
carbamazepine  (ISO)
carbaryl  (ISO)
carbon nanotube  (EXP,ISO)
casticin  (ISO)
cerium  (ISO)
cerulenin  (ISO)
ceruletide  (ISO)
CGP 52608  (ISO)
chloroacetaldehyde  (ISO)
chloroacetic acid  (EXP)
chlorogenic acid  (ISO)
chloropicrin  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
choline  (EXP)
chrysene  (EXP)
cidofovir anhydrous  (ISO)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
cordycepin  (EXP)
curcumin  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (EXP,ISO)
D-penicillamine  (ISO)
dantrolene  (EXP)
deguelin  (ISO)
deoxynivalenol  (EXP)
desferrioxamine B  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP,ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (ISO)
diclofenac  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ebselen  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP)
ethylbenzene  (ISO)
ethylene glycol  (ISO)
fenofibrate  (ISO)
fenpyroximate  (ISO)
fentin chloride  (ISO)
ferric ammonium citrate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
fructose  (EXP)
furan  (EXP,ISO)
gadolinium trichloride  (ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
glucose  (EXP,ISO)
glutathione  (ISO)
glycine  (ISO)
glycyrrhetinate  (ISO)
glycyrrhetinic acid  (ISO)
graphene oxide  (ISO)
hemin  (EXP)
hexadecanoic acid  (EXP,ISO)
homocysteine  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (EXP,ISO)
hydroxychloroquine  (ISO)
ibuprofen  (ISO)
Ibutilide  (ISO)
ifosfamide  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
indoxyl sulfate  (EXP)
isoliquiritigenin  (ISO)
ketamine  (EXP)
L-1,4-dithiothreitol  (ISO)
L-glutamic acid  (ISO)
L-methionine  (EXP)
lactacystin  (ISO)
lanthanum atom  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
letrozole  (ISO)
linuron  (EXP,ISO)
lipopolysaccharide  (EXP,ISO)
luteolin  (ISO)
lycopene  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melatonin  (EXP,ISO)
menadione  (ISO)
metformin  (EXP,ISO)
methamphetamine  (EXP,ISO)
methidathion  (EXP)
methotrexate  (ISO)
methylmercury chloride  (EXP,ISO)
methylseleninic acid  (ISO)
mevastatin  (EXP)
microcystin-LR  (EXP)
minocycline  (ISO)
MK-2206  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
montelukast  (EXP)
Mycotrienin II  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
nefazodone  (ISO)
nicotine  (ISO)
nilotinib  (ISO)
Nodularin  (ISO)
o-xylene  (ISO)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oleic acid  (EXP,ISO)
orlistat  (ISO)
ozone  (ISO)
Pachymic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
patulin  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
permethrin  (ISO)
phenobarbital  (EXP)
picene  (ISO)
picoxystrobin  (ISO)
pinostrobin  (ISO)
pirinixic acid  (EXP)
potassium iodide  (ISO)
prallethrin  (ISO)
procymidone  (EXP)
progesterone  (ISO)
propylparaben  (EXP)
pyrazinecarboxamide  (ISO)
quercetin  (EXP,ISO)
reactive oxygen species  (ISO)
resveratrol  (EXP,ISO)
Riluzole  (ISO)
rimonabant  (ISO)
rotenone  (EXP,ISO)
Salidroside  (EXP)
SB 431542  (ISO)
SCH 23390  (ISO)
serpentine asbestos  (EXP,ISO)
sertraline  (ISO)
Shikonin  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sincalide  (ISO)
sirolimus  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Sodium iodate  (EXP,ISO)
sorafenib  (ISO)
SR 144528  (ISO)
streptozocin  (EXP,ISO)
sulfasalazine  (ISO)
sulforaphane  (EXP,ISO)
sulfur dioxide  (ISO)
sulindac  (ISO)
sunitinib  (ISO)
T-2 toxin  (EXP,ISO)
tacrolimus hydrate  (EXP)
tamibarotene  (ISO)
tamoxifen  (EXP)
tauroursodeoxycholic acid  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (EXP,ISO)
Theaflavin 3,3'-digallate  (ISO)
thifluzamide  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
toyocamycin  (EXP)
tributylstannane  (ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
triclosan  (EXP)
Trienomycin A  (ISO)
trierixin  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
tunicamycin  (EXP,ISO)
urethane  (ISO)
usnic acid  (ISO)
valproic acid  (EXP,ISO)
vanillic acid  (ISO)
withaferin A  (ISO)
zearalenone  (ISO)
zinc oxide  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adipose tissue development  (IMP)
angiogenesis  (IMP)
apoptotic process  (IEA)
autophagy  (IEA)
cell differentiation  (IEA)
cellular response to amino acid stimulus  (IDA)
cellular response to antibiotic  (ISO)
cellular response to fluid shear stress  (ISO)
cellular response to fructose stimulus  (IDA)
cellular response to glucose starvation  (IDA)
cellular response to glucose stimulus  (IDA)
cellular response to insulin stimulus  (IDA)
cellular response to interleukin-4  (IDA)
cellular response to laminar fluid shear stress  (ISO)
cellular response to leukemia inhibitory factor  (IEP)
cellular response to lipopolysaccharide  (IDA,ISO)
cellular response to nutrient  (IDA)
cellular response to oxidative stress  (ISO)
cellular response to peptide hormone stimulus  (IDA)
cellular response to vascular endothelial growth factor stimulus  (ISO)
cholesterol homeostasis  (IMP)
endoplasmic reticulum unfolded protein response  (IDA,IMP,ISO)
endothelial cell proliferation  (IMP,ISO)
epithelial cell maturation involved in salivary gland development  (IMP)
exocrine pancreas development  (IMP)
fatty acid homeostasis  (IMP)
glandular epithelial cell maturation  (IMP)
intracellular triglyceride homeostasis  (IMP)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress  (IMP)
lipid metabolic process  (IEA)
liver development  (IMP)
muscle organ development  (IEA)
negative regulation of apoptotic process  (IMP)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (ISO)
negative regulation of endoplasmic reticulum unfolded protein response  (ISO)
negative regulation of ERK1 and ERK2 cascade  (ISO)
negative regulation of myotube differentiation  (IDA)
negative regulation of SMAD protein signal transduction  (ISO)
negative regulation of transcription by RNA polymerase II  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
neuron development  (IDA)
phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of autophagy  (ISO)
positive regulation of B cell differentiation  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of endoplasmic reticulum unfolded protein response  (ISO)
positive regulation of endothelial cell apoptotic process  (ISO)
positive regulation of fat cell differentiation  (IMP)
positive regulation of hepatocyte proliferation  (IMP)
positive regulation of immunoglobulin production  (IDA,ISO)
positive regulation of interleukin-6 production  (IDA)
positive regulation of lactation  (IMP)
positive regulation of MHC class II biosynthetic process  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (ISO)
positive regulation of plasma cell differentiation  (ISO)
positive regulation of protein acetylation  (ISO)
positive regulation of protein import into nucleus  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of T cell differentiation  (ISO)
positive regulation of TOR signaling  (ISO)
positive regulation of transcription by RNA polymerase II  (IDA,IMP,ISO)
positive regulation of vascular associated smooth muscle cell migration  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (ISO)
positive regulation of vascular wound healing  (ISO)
protein destabilization  (IMP,ISO)
protein transport  (IEA)
regulation of autophagy  (IMP)
regulation of cell growth  (ISO)
regulation of DNA-templated transcription  (IEA)
regulation of protein stability  (ISO)
regulation of transcription by RNA polymerase II  (IDA)
response to electrical stimulus  (ISO)
response to endoplasmic reticulum stress  (IDA,ISO)
response to insulin-like growth factor stimulus  (IDA)
response to nutrient  (ISO)
response to unfolded protein  (IEA)
response to xenobiotic stimulus  (ISO)
serotonin secretion, neurotransmission  (ISO)
sterol homeostasis  (IMP)
transcription by RNA polymerase II  (IDA,ISO)
ubiquitin-dependent protein catabolic process  (IMP)
vascular endothelial growth factor receptor signaling pathway  (ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal autophagy  (IAGP)
abnormal blood flow velocity  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal bone mineralization  (IEA)
abnormal bone structure  (IEA)
abnormal cell migration  (IAGP)
abnormal endoplasmic reticulum morphology  (IAGP)
abnormal enterocyte physiology  (IAGP)
abnormal extraembryonic tissue physiology  (IAGP)
abnormal heart development  (IAGP)
abnormal intestine physiology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal liver development  (IAGP)
abnormal nucleotide metabolism  (IAGP)
abnormal Paneth cell morphology  (IAGP)
abnormal physiological neovascularization  (IAGP)
abnormal response to injury  (IAGP)
abnormal retina blood vessel morphology  (IAGP)
abnormal small intestine goblet cell morphology  (IAGP)
absent Paneth cells  (IAGP)
absent trabeculae carneae  (IAGP)
anemia  (IAGP)
anoxia  (IAGP)
cachexia  (IAGP)
crypts of Lieberkuhn abscesses  (IAGP)
decreased angiogenesis  (IAGP)
decreased cell proliferation  (IAGP)
decreased cholesterol level  (IAGP)
decreased circulating cholesterol level  (IEA)
decreased circulating triglyceride level  (IAGP)
decreased embryo size  (IAGP)
decreased embryo weight  (IAGP)
decreased fatty acids level  (IAGP)
decreased hepatocyte proliferation  (IAGP)
decreased IgG1 level  (IEA)
decreased large unstained cell number  (IEA)
decreased leukocyte cell number  (IEA)
decreased lymphocyte cell number  (IEA)
decreased Paneth cell number  (IAGP)
decreased red blood cell distribution width  (IEA)
decreased small intestinal villus size  (IAGP)
decreased susceptibility to prion infection  (IAGP)
decreased T cell number  (IEA)
embryo tissue necrosis  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged pericardium  (IAGP)
ileum inflammation  (IAGP)
impaired hematopoiesis  (IAGP)
increased apoptosis  (IAGP)
increased body fat mass  (IAGP)
increased enterocyte apoptosis  (IAGP)
increased grip strength  (IEA)
increased hepatocyte apoptosis  (IAGP)
increased mean corpuscular hemoglobin  (IEA)
increased mean corpuscular volume  (IEA)
increased susceptibility to bacterial infection  (IAGP)
increased susceptibility to induced colitis  (IAGP)
intestinal inflammation  (IAGP)
intestinal ulcer  (IAGP)
liver hypoplasia  (IAGP)
myocardium necrosis  (IAGP)
pallor  (IAGP)
persistence of hyaloid vascular system  (IEA)
preweaning lethality, complete penetrance  (IEA)
rectal hemorrhage  (IAGP)
small intestinal inflammation  (IAGP)
small liver  (IAGP)
thin ventricular wall  (IAGP)
vertebral fusion  (IEA)
wavy neural tube  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. Expression of XBP1s in peritoneal mesothelial cells is critical for inflammation-induced peritoneal fibrosis. Liu A, etal., Sci Rep. 2019 Dec 13;9(1):19043. doi: 10.1038/s41598-019-55557-1.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Nikaido T, etal., Histochem Cell Biol 2001 Aug;116(2):141-8.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Ozcan U, etal., Science. 2004 Oct 15;306(5695):457-61.
12. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
13. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14. The dysregulation of endoplasmic reticulum stress response in acute-on-chronic liver failure patients caused by acute exacerbation of chronic hepatitis B. Ren F, etal., J Viral Hepat. 2016 Jan;23(1):23-31. doi: 10.1111/jvh.12438. Epub 2015 Jul 31.
15. Mouse MP Annotation Import Pipeline RGD automated import pipeline
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells. Tan Z, etal., J Neuroinflammation. 2018 Sep 21;15(1):275. doi: 10.1186/s12974-018-1311-5.
18. The impact of the unfolded protein response on human disease. Wang S and Kaufman RJ, J Cell Biol. 2012 Jun 25;197(7):857-67. doi: 10.1083/jcb.201110131.
19. Endoplasmic reticulum stress and neurodegeneration in rats neonatally infected with borna disease virus. Williams BL and Lipkin WI, J Virol. 2006 Sep;80(17):8613-26. doi: 10.1128/JVI.00836-06.
20. Effect of Creosote Bush-Derived NDGA on Expression of Genes Involved in Lipid Metabolism in Liver of High-Fructose Fed Rats: Relevance to NDGA Amelioration of Hypertriglyceridemia and Hepatic Steatosis. Zhang H, etal., PLoS One. 2015 Sep 22;10(9):e0138203. doi: 10.1371/journal.pone.0138203. eCollection 2015.
Additional References at PubMed
PMID:7693055   PMID:8657566   PMID:8889548   PMID:9676189   PMID:10349636   PMID:10425189   PMID:10652269   PMID:10907849   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11437488  
PMID:11780124   PMID:11812828   PMID:12477932   PMID:12612580   PMID:12729558   PMID:14559994   PMID:14610273   PMID:14647274   PMID:14702639   PMID:14756820   PMID:15345222   PMID:15459690  
PMID:15466483   PMID:15489334   PMID:15598891   PMID:15782199   PMID:15882996   PMID:16103408   PMID:16141072   PMID:16141073   PMID:16332684   PMID:16362047   PMID:16416089   PMID:16452489  
PMID:16469704   PMID:16644724   PMID:16847323   PMID:17037520   PMID:17090218   PMID:17213183   PMID:17367944   PMID:17540781   PMID:17609113   PMID:17612490   PMID:17709512   PMID:17765680  
PMID:17875675   PMID:17890727   PMID:17913437   PMID:18178615   PMID:18182158   PMID:18287559   PMID:18412159   PMID:18417469   PMID:18437163   PMID:18528784   PMID:18554416   PMID:18556558  
PMID:18775308   PMID:18776938   PMID:18809377   PMID:18832700   PMID:19117545   PMID:19129515   PMID:19135031   PMID:19188447   PMID:19247368   PMID:19321437   PMID:19328063   PMID:19352619  
PMID:19379700   PMID:19407814   PMID:19416856   PMID:19454701   PMID:19490910   PMID:19591821   PMID:19710472   PMID:19752183   PMID:19762508   PMID:19805353   PMID:19855189   PMID:19858219  
PMID:20059953   PMID:20070977   PMID:20080679   PMID:20146926   PMID:20178780   PMID:20197277   PMID:20208012   PMID:20211142   PMID:20348923   PMID:20348926   PMID:20351694   PMID:20353876  
PMID:20408817   PMID:20412781   PMID:20439489   PMID:20660350   PMID:20668028   PMID:20692302   PMID:20816838   PMID:20955178   PMID:21044701   PMID:21138840   PMID:21267068   PMID:21310900  
PMID:21317886   PMID:21357531   PMID:21368889   PMID:21385877   PMID:21400498   PMID:21415858   PMID:21447637   PMID:21555585   PMID:21677750   PMID:21704586   PMID:21784843   PMID:21795745  
PMID:21873635   PMID:21892182   PMID:22128176   PMID:22154935   PMID:22215619   PMID:22253482   PMID:22291093   PMID:22337954   PMID:22431749   PMID:22643896   PMID:22692508   PMID:22715395  
PMID:22745161   PMID:22768244   PMID:22808162   PMID:22925926   PMID:22961053   PMID:22961085   PMID:22988430   PMID:23040069   PMID:23040070   PMID:23133675   PMID:23144714   PMID:23152784  
PMID:23184933   PMID:23235147   PMID:23257357   PMID:23395094   PMID:23447676   PMID:23493568   PMID:23529610   PMID:23541586   PMID:23578819   PMID:23603388   PMID:23623498   PMID:23979843  
PMID:23990788   PMID:24043762   PMID:24053669   PMID:24089213   PMID:24194600   PMID:24225943   PMID:24241534   PMID:24242955   PMID:24332809   PMID:24348270   PMID:24441789   PMID:24475193  
PMID:24489101   PMID:24508390   PMID:24519940   PMID:24630721   PMID:24670948   PMID:24721909   PMID:24726366   PMID:24753614   PMID:24797433   PMID:24812669   PMID:24821775   PMID:24945730  
PMID:24952961   PMID:25078688   PMID:25147951   PMID:25170079   PMID:25223794   PMID:25332179   PMID:25332234   PMID:25333725   PMID:25373918   PMID:25600960   PMID:25656649   PMID:25713103  
PMID:25754093   PMID:25821218   PMID:25844898   PMID:25973683   PMID:26026678   PMID:26106220   PMID:26112372   PMID:26135354   PMID:26147683   PMID:26173459   PMID:26174230   PMID:26193638  
PMID:26245636   PMID:26303067   PMID:26315405   PMID:26319553   PMID:26372225   PMID:26383973   PMID:26403762   PMID:26472223   PMID:26483413   PMID:26494538   PMID:26504083   PMID:26562262  
PMID:26568450   PMID:26678450   PMID:26773096   PMID:26779600   PMID:26792861   PMID:26816051   PMID:26854229   PMID:26906090   PMID:26925839   PMID:26951929   PMID:27052593   PMID:27055562  
PMID:27133203   PMID:27149841   PMID:27261193   PMID:27276683   PMID:27283502   PMID:27325692   PMID:27338006   PMID:27378176   PMID:27416896   PMID:27436040   PMID:27570073   PMID:27626380  
PMID:27626662   PMID:27644325   PMID:27646263   PMID:27701635   PMID:27729526   PMID:27814504   PMID:27853315   PMID:28028078   PMID:28039331   PMID:28082079   PMID:28082357   PMID:28167662  
PMID:28237965   PMID:28332979   PMID:28459443   PMID:28474670   PMID:28535855   PMID:28588082   PMID:28614720   PMID:28620068   PMID:28687614   PMID:28726788   PMID:28743992   PMID:28747426  
PMID:29089350   PMID:29129613   PMID:29157602   PMID:29320742   PMID:29400713   PMID:29482168   PMID:29507125   PMID:29511123   PMID:29551634   PMID:29615095   PMID:29666470   PMID:29891850  
PMID:29939162   PMID:30111834   PMID:30146262   PMID:30254094   PMID:30282030   PMID:30305738   PMID:30457570   PMID:30482806   PMID:30612139   PMID:30619478   PMID:30635284   PMID:30649389  
PMID:30655546   PMID:30685387   PMID:30745418   PMID:30778220   PMID:30819965   PMID:30943188   PMID:30973754   PMID:30973865   PMID:31086333   PMID:31123148   PMID:31135066   PMID:31138662  
PMID:31242599   PMID:31260448   PMID:31296559   PMID:31320508   PMID:31369074   PMID:31436800   PMID:31492921   PMID:31541078   PMID:31543404   PMID:31601454   PMID:31630283   PMID:31781038  
PMID:31806625   PMID:31837300   PMID:31882545   PMID:31888027   PMID:31907348   PMID:31935211   PMID:32005751   PMID:32024827   PMID:32065579   PMID:32249615   PMID:32313051   PMID:32376649  
PMID:32386518   PMID:32397573   PMID:32597296   PMID:32673694   PMID:32758541   PMID:32788214   PMID:32926479   PMID:32958856   PMID:33277471   PMID:33403797   PMID:33600817   PMID:33654072  
PMID:33722606   PMID:33727534   PMID:33891366   PMID:33909046   PMID:34030589   PMID:34057287   PMID:34240701   PMID:34318710   PMID:34325487   PMID:34380029   PMID:34421344   PMID:34548333  
PMID:34550724   PMID:34599932   PMID:34659198   PMID:34686867   PMID:34812145   PMID:34870453   PMID:34975335   PMID:35030194   PMID:35031299   PMID:35105890   PMID:35129674   PMID:35145060  
PMID:35147267   PMID:35167946   PMID:35173538   PMID:35263593   PMID:35292349   PMID:35316840   PMID:35367811   PMID:35377412   PMID:35727638   PMID:35915851   PMID:36012265   PMID:36012294  
PMID:36162519   PMID:36184383   PMID:36270750   PMID:36314651   PMID:36370432   PMID:36618345   PMID:36801911   PMID:36841836   PMID:36894627   PMID:36897958   PMID:36916341   PMID:36917985  
PMID:37016577   PMID:37025177   PMID:37224754   PMID:37346037   PMID:37353485   PMID:37457727   PMID:37753803   PMID:37874641   PMID:37875231   PMID:37998373   PMID:38015176   PMID:38218976  
PMID:38355793  


Genomics

Comparative Map Data
Xbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39115,470,641 - 5,475,993 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl115,470,659 - 5,475,893 (+)EnsemblGRCm39 Ensembl
GRCm38115,520,641 - 5,525,993 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl115,520,659 - 5,525,893 (+)EnsemblGRCm38mm10GRCm38
MGSCv37115,420,970 - 5,425,875 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36115,420,970 - 5,425,875 (+)NCBIMGSCv36mm8
Celera116,013,954 - 6,018,865 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map113.61NCBI
XBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382228,794,560 - 28,800,569 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2228,794,555 - 28,800,597 (-)EnsemblGRCh38hg38GRCh38
GRCh372229,190,548 - 29,196,557 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362227,520,548 - 27,526,560 (-)NCBINCBI36Build 36hg18NCBI36
Build 342227,515,102 - 27,521,114NCBI
Celera2212,990,518 - 12,996,530 (-)NCBICelera
Cytogenetic Map22q12.1NCBI
HuRef2212,155,463 - 12,161,487 (-)NCBIHuRef
CHM1_12229,149,582 - 29,155,594 (-)NCBICHM1_1
T2T-CHM13v2.02229,255,848 - 29,261,869 (-)NCBIT2T-CHM13v2.0
Xbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81484,604,623 - 84,609,707 (+)NCBIGRCr8
mRatBN7.21480,390,629 - 80,395,713 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1480,390,643 - 80,395,693 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1484,792,890 - 84,797,957 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01486,033,004 - 86,038,075 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01482,482,326 - 82,487,393 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01485,753,736 - 85,758,820 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1485,753,760 - 85,758,145 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01486,423,839 - 86,428,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41486,151,910 - 86,156,975 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11486,171,054 - 86,176,119 (+)NCBI
Celera1479,276,264 - 79,281,348 (+)NCBICelera
Cytogenetic Map14q21NCBI
Xbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554553,037,885 - 3,041,827 (-)NCBIChiLan1.0ChiLan1.0
XBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22338,792,985 - 38,799,011 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12241,491,735 - 41,497,760 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0229,863,479 - 9,869,491 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12227,566,423 - 27,572,627 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2227,567,041 - 27,571,943 (-)Ensemblpanpan1.1panPan2
XBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12622,162,675 - 22,168,149 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2622,163,222 - 22,168,105 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2622,034,265 - 22,039,738 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02622,536,044 - 22,541,803 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2622,536,033 - 22,541,796 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12622,246,365 - 22,251,835 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02622,509,837 - 22,515,563 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02622,572,658 - 22,578,379 (-)NCBIUU_Cfam_GSD_1.0
Xbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118112,975,309 - 112,979,534 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366572,891,907 - 2,896,174 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366572,891,171 - 2,895,409 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
XBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1446,008,377 - 46,016,526 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11446,011,239 - 46,016,526 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21449,015,849 - 49,016,650 (-)NCBISscrofa10.2Sscrofa10.2susScr3
XBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11911,670,605 - 11,677,168 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666045114,476,586 - 114,483,163 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Xbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247475,123,085 - 5,128,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Xbp1
219 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:848
Count of miRNA genes:472
Interacting mature miRNAs:531
Transcripts:ENSMUST00000063084, ENSMUST00000145588, ENSMUST00000149159, ENSMUST00000149623
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357722Vtbt11_mvertebral trabecular bone trait 11 (mouse)Not determined11123880487Mouse
1300768Tshp9_mtooth shape 9 (mouse)Not determined11125976374Mouse
1301765Skull15_mskull morphology 15 (mouse)Not determined11125976374Mouse
1300661Lmr6_mleishmaniasis resistance 6 (mouse)Not determined11125976374Mouse
10044008Hbnr15_mHeligmosomoides bakeri nematode resistance 15 (mouse)Not determined1122705234227232Mouse
1300599Cocrb11_mcocaine related behavior 11 (mouse)Not determined11267035536671472Mouse
27095914Pglq16_mpelvic girdle length QTL 16, 16 week (mouse)11325000018150000Mouse
27095919Pglq10_mpelvic girdle length QTL 10, 10 week (mouse)11325000018450000Mouse
27095925Pglq5_mpelvic girdle length QTL 5, 5 week (mouse)11325000019750000Mouse
27095904Scvln12_msacral vertebrae length 2, 10 week (mouse)11325000034495048Mouse
27095909Scvln6_msacral vertebrae length 2, 5 week (mouse)11325000044090827Mouse
27226798Scvln18_msacral vertebrae length 2, 16 week (mouse)11325000060690826Mouse
26884446Sklq10_mskull length QTL 10, 10 week (mouse)11325000062890826Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
10053676Eae44a_mexperimental allergic encephalomyelitis susceptibility 44a (mouse)Not determined11450789621379532Mouse
27226741Metcl5_mmetatarsal-calcaneal length 5, 5 week (mouse)11465000046290827Mouse
27226735Metcl16_mmetatarsal-calcaneal length 16, 16 week (mouse)11525000035090827Mouse

Markers in Region
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,523,435 - 5,524,837UniSTSGRCm38
MGSCv37115,424,738 - 5,425,710UniSTSGRCm37
MGSCv37115,421,041 - 5,422,016UniSTSGRCm37
MGSCv37115,423,398 - 5,424,373UniSTSGRCm37
Celera116,016,430 - 6,017,830UniSTS
Cytogenetic Map11A1UniSTS
cM Map113.0UniSTS
RH126157  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,525,562 - 5,525,803UniSTSGRCm38
MGSCv37115,425,565 - 5,425,806UniSTSGRCm37
Celera116,018,556 - 6,018,796UniSTS
Cytogenetic Map11A1UniSTS
cM Map113.0UniSTS
Whitehead/MRC_RH1128.09UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,524,735 - 5,525,707UniSTSGRCm38
MGSCv37115,424,738 - 5,425,710UniSTSGRCm37
Celera116,017,728 - 6,018,700UniSTS
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,523,395 - 5,524,370UniSTSGRCm38
MGSCv37115,423,398 - 5,424,373UniSTSGRCm37
Celera116,016,390 - 6,017,363UniSTS
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,521,038 - 5,522,013UniSTSGRCm38
MGSCv37115,421,041 - 5,422,016UniSTSGRCm37
Celera116,014,025 - 6,015,000UniSTS
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,524,270 - 5,524,359UniSTSGRCm38
Celera116,017,263 - 6,017,352UniSTS
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11A1UniSTS
Xbp1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38115,525,298 - 5,525,521UniSTSGRCm38
Celera116,018,291 - 6,018,515UniSTS
Cytogenetic Map11A1UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_013842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB036745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF027963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF443192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK145241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK180092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183866 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK207925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK217907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK219822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK220033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC035452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF453945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG800705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000063084   ⟹   ENSMUSP00000054852
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,470,659 - 5,475,893 (+)Ensembl
GRCm38.p6 Ensembl115,520,659 - 5,525,893 (+)Ensembl
RefSeq Acc Id: ENSMUST00000145588
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,471,005 - 5,474,026 (+)Ensembl
GRCm38.p6 Ensembl115,521,005 - 5,524,026 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149159   ⟹   ENSMUSP00000134088
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,471,923 - 5,475,105 (+)Ensembl
GRCm38.p6 Ensembl115,521,923 - 5,525,105 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149623   ⟹   ENSMUSP00000135768
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,471,663 - 5,474,943 (+)Ensembl
GRCm38.p6 Ensembl115,521,663 - 5,524,943 (+)Ensembl
RefSeq Acc Id: ENSMUST00000239150   ⟹   ENSMUSP00000158915
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl115,470,995 - 5,475,242 (+)Ensembl
GRCm38.p6 Ensembl115,520,995 - 5,525,242 (+)Ensembl
RefSeq Acc Id: NM_001271730   ⟹   NP_001258659
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,470,641 - 5,475,993 (+)NCBI
GRCm38115,520,641 - 5,525,993 (+)NCBI
Celera116,013,628 - 6,018,986 (+)NCBI
Sequence:
RefSeq Acc Id: NM_013842   ⟹   NP_038870
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39115,470,641 - 5,475,993 (+)NCBI
GRCm38115,520,641 - 5,525,993 (+)NCBI
MGSCv37115,420,970 - 5,425,875 (+)RGD
Celera116,013,628 - 6,018,986 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_038870   ⟸   NM_013842
- Peptide Label: isoform XBP1(U)
- UniProtKB: Q922G5 (UniProtKB/Swiss-Prot),   Q8VHM0 (UniProtKB/Swiss-Prot),   Q9ESS3 (UniProtKB/Swiss-Prot),   O35426 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001258659   ⟸   NM_001271730
- Peptide Label: isoform XBP1(S)
- UniProtKB: A0A5F8MPD3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000158915   ⟸   ENSMUST00000239150
RefSeq Acc Id: ENSMUSP00000135768   ⟸   ENSMUST00000149623
RefSeq Acc Id: ENSMUSP00000134088   ⟸   ENSMUST00000149159
RefSeq Acc Id: ENSMUSP00000054852   ⟸   ENSMUST00000063084
Protein Domains
bZIP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O35426-F1-model_v2 AlphaFold O35426 1-267 view protein structure

Promoters
RGD ID:6822477
Promoter ID:MM_KWN:6294
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000109866,   OTTMUST00000014402,   OTTMUST00000014403,   OTTMUST00000014405,   UC007HWN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,419,946 - 5,421,982 (+)MPROMDB
RGD ID:6822476
Promoter ID:MM_KWN:6295
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   MEF_B6
Transcripts:OTTMUST00000014404
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,422,471 - 5,423,232 (+)MPROMDB
RGD ID:6822481
Promoter ID:MM_KWN:6296
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B6
Transcripts:UC007HWO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,423,271 - 5,424,512 (+)MPROMDB
RGD ID:6846936
Promoter ID:MM_ACW:6632
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day6
Transcripts:XBP1.QSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36115,428,991 - 5,429,491 (+)MPROMDB
RGD ID:8673842
Promoter ID:EPDNEW_M14951
Type:multiple initiation site
Name:Xbp1_2
Description:Mus musculus X-box binding protein 1 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14952  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38115,520,654 - 5,520,714EPDNEW
RGD ID:8673846
Promoter ID:EPDNEW_M14952
Type:initiation region
Name:Xbp1_1
Description:Mus musculus X-box binding protein 1 , transcript variant 2,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M14951  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38115,520,980 - 5,521,040EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98970 AgrOrtholog
Ensembl Genes ENSMUSG00000020484 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000063084 ENTREZGENE
  ENSMUST00000063084.16 UniProtKB/Swiss-Prot
  ENSMUST00000149159.3 UniProtKB/TrEMBL
  ENSMUST00000149623.8 UniProtKB/TrEMBL
  ENSMUST00000239150 ENTREZGENE
  ENSMUST00000239150.2 UniProtKB/TrEMBL
  ENSMUST00000239150.3 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro bZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bZIP_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:22433 UniProtKB/Swiss-Prot
MGD MGI:98970 ENTREZGENE
NCBI Gene 22433 ENTREZGENE
PANTHER BZIP DOMAIN-CONTAINING PROTEIN UniProtKB/TrEMBL
  X-BOX BINDING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  X-BOX-BINDING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam bZIP_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Xbp1 PhenoGen
PROSITE BZIP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  BZIP_BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BRLZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A5F8MPD3 ENTREZGENE, UniProtKB/TrEMBL
  G3UYH6_MOUSE UniProtKB/TrEMBL
  H3BLF6_MOUSE UniProtKB/TrEMBL
  O35426 ENTREZGENE
  Q05DE6_MOUSE UniProtKB/TrEMBL
  Q8VHM0 ENTREZGENE
  Q922G5 ENTREZGENE
  Q9ESS3 ENTREZGENE
  XBP1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8VHM0 UniProtKB/Swiss-Prot
  Q922G5 UniProtKB/Swiss-Prot
  Q9ESS3 UniProtKB/Swiss-Prot