Hspb8 (heat shock protein 8) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Hspb8 (heat shock protein 8) Mus musculus
Analyze
Symbol: Hspb8
Name: heat shock protein 8
RGD ID: 735524
MGI Page MGI
Description: Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study autosomal dominant distal hereditary motor neuronopathy 2. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and autosomal dominant distal hereditary motor neuronopathy 2. Orthologous to human HSPB8 (heat shock protein family B (small) member 8).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: alpha-crystallin C chain; AU018630; AW413033; Cry; Cryac; crystallin, alpha C; D5Ucl; D5Ucla4; E2IG; E2IG1; H11; H11K; heat shock 27kDa protein 8; heat shock protein 20-like protein; heat shock protein beta-8; HSP; HSP20-; HSP20-like; HSP22; small stress protein-like protein HSP22
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395116,546,550 - 116,560,923 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5116,546,550 - 116,560,923 (-)EnsemblGRCm39 Ensembl
GRCm385116,408,491 - 116,422,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5116,408,491 - 116,422,864 (-)EnsemblGRCm38mm10GRCm38
MGSCv375116,858,504 - 116,872,873 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365116,669,494 - 116,683,863 (-)NCBIMGSCv36mm8
Celera5113,505,586 - 113,520,087 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.41NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17beta-estradiol  (ISO)
1H-pyrazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
acrylamide  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha,alpha-trehalose  (EXP)
alpha-Zearalanol  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antimonite  (ISO)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
astemizole  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
Butylparaben  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
cantharidin  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloroethene  (EXP)
chlorpyrifos  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
cyproconazole  (ISO)
deoxycholic acid  (ISO)
diarsenic trioxide  (ISO)
diclofenac  (EXP)
dioxygen  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
diquat  (EXP)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
fenofibrate  (EXP)
fluoxetine  (ISO)
flutamide  (ISO)
furan  (ISO)
genistein  (ISO)
gentamycin  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
hydrazine  (EXP)
hydrogen peroxide  (EXP)
iron dichloride  (ISO)
lactulose  (EXP)
Licochalcone B  (ISO)
lipopolysaccharide  (EXP,ISO)
LY294002  (ISO)
manganese(II) chloride  (ISO)
melibiose  (EXP)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methotrexate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methylformamide  (EXP)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
nimesulide  (ISO)
organoselenium compound  (ISO)
ozone  (EXP)
paracetamol  (EXP,ISO)
pentachlorophenol  (EXP)
pentanal  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
phlorizin  (EXP)
phorone  (ISO)
pirinixic acid  (EXP)
potassium dichromate  (EXP)
prochloraz  (ISO)
progesterone  (ISO)
propanal  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
ranitidine  (ISO)
resveratrol  (EXP)
rotenone  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sirolimus  (ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium dodecyl sulfate  (ISO)
sodium fluoride  (EXP)
Soman  (ISO)
tamoxifen  (EXP,ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
tributylstannane  (ISO)
trichloroethene  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valdecoxib  (ISO)
valproic acid  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)
protein folding chaperone complex  (IBA,ISO)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27). Benndorf R, etal., J Biol Chem 2001 Jul 20;276(29):26753-61.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Cloning and genomic localization of the murine LPS-induced CXC chemokine (LIX) gene, Scyb5. Smith JB, etal., Immunogenetics 2002 Nov;54(8):599-603. Epub 2002 Oct 1.
12. Linkage mapping of 40 randomly isolated liver cDNA clones in the mouse. Warden CH, etal., Genomics 1993 Nov;18(2):295-307.
Additional References at PubMed
PMID:8827514   PMID:8889548   PMID:9321482   PMID:9383292   PMID:10349636   PMID:10438476   PMID:10603348   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11133685   PMID:11591653  
PMID:11714668   PMID:12477932   PMID:14610273   PMID:14681479   PMID:15122253   PMID:15489334   PMID:15543936   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16373598   PMID:16602821  
PMID:17366632   PMID:17661394   PMID:18006445   PMID:18384969   PMID:18675797   PMID:20060297   PMID:20538880   PMID:20570967   PMID:21267068   PMID:21747053   PMID:21873635   PMID:22213583  
PMID:22542467   PMID:22794259   PMID:23055939   PMID:23389032   PMID:23536091   PMID:24952961   PMID:25746286   PMID:26199678   PMID:27178361   PMID:27396899   PMID:28378742   PMID:28780615  
PMID:29532456   PMID:30922561   PMID:31047988   PMID:32325033   PMID:33742095   PMID:34321999   PMID:35055033   PMID:35148379   PMID:35958024   PMID:37399610   PMID:37522952   PMID:38355793  


Genomics

Comparative Map Data
Hspb8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395116,546,550 - 116,560,923 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5116,546,550 - 116,560,923 (-)EnsemblGRCm39 Ensembl
GRCm385116,408,491 - 116,422,864 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5116,408,491 - 116,422,864 (-)EnsemblGRCm38mm10GRCm38
MGSCv375116,858,504 - 116,872,873 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365116,669,494 - 116,683,863 (-)NCBIMGSCv36mm8
Celera5113,505,586 - 113,520,087 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.41NCBI
HSPB8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812119,178,931 - 119,194,746 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12119,171,555 - 119,224,855 (+)EnsemblGRCh38hg38GRCh38
GRCh3712119,616,736 - 119,632,551 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612118,100,978 - 118,116,934 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412118,079,314 - 118,095,270NCBI
Celera12119,249,740 - 119,265,695 (+)NCBICelera
Cytogenetic Map12q24.23NCBI
HuRef12116,624,758 - 116,640,724 (+)NCBIHuRef
CHM1_112119,584,428 - 119,600,385 (+)NCBICHM1_1
T2T-CHM13v2.012119,166,359 - 119,182,179 (+)NCBIT2T-CHM13v2.0
Hspb8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81245,835,899 - 45,866,449 (+)NCBIGRCr8
mRatBN7.21240,176,405 - 40,205,002 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1240,176,532 - 40,191,185 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1241,351,855 - 41,366,486 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01241,965,698 - 41,980,331 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01241,026,095 - 41,040,728 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01245,905,371 - 45,920,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,905,371 - 45,920,013 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01247,717,762 - 47,731,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41241,407,166 - 41,421,565 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11241,270,553 - 41,284,952 (+)NCBI
Celera1241,813,553 - 41,828,157 (+)NCBICelera
Cytogenetic Map12q16NCBI
Hspb8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545512,290,587 - 12,304,656 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545512,290,884 - 12,304,588 (-)NCBIChiLan1.0ChiLan1.0
HSPB8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210127,244,376 - 127,260,703 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112127,240,755 - 127,257,082 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012116,758,785 - 116,774,883 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112120,136,986 - 120,153,102 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12120,136,986 - 120,153,102 (+)Ensemblpanpan1.1panPan2
HSPB8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12615,337,718 - 15,349,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2615,336,864 - 15,355,757 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2615,343,116 - 15,355,393 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02615,606,043 - 15,618,322 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2615,605,664 - 15,625,601 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12615,575,862 - 15,588,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02615,643,221 - 15,655,514 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02615,685,151 - 15,697,445 (+)NCBIUU_Cfam_GSD_1.0
Hspb8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118146,997,711 - 147,017,378 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366681,496,600 - 1,505,650 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPB8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1433,626,120 - 33,640,792 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11433,626,125 - 33,639,824 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21435,688,321 - 35,701,952 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HSPB8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111114,522,236 - 114,540,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11114,522,248 - 114,540,477 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037130,563,295 - 130,581,391 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspb8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474714,383,421 - 14,397,528 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474714,383,600 - 14,397,440 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hspb8
462 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:457
Count of miRNA genes:305
Interacting mature miRNAs:354
Transcripts:ENSMUST00000036991, ENSMUST00000133335
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
4142064Tmc1m4_mTmc1 modifier 4 (mouse)Not determined554500177127001072Mouse
26884395Humsd2_mhumerus midshaft diameter 2, 10 week (mouse)570057343132528839Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
25314315Mlh1fc4_mMLH1 foci count 4 (mouse)574460661132528839Mouse
13506928Recrq8_mrecombination rate in male meiosis QTL 8 (mouse)574460661132528839Mouse
1357431Cia27_mcollagen induced arthritis 27 (mouse)Not determined575315348120018629Mouse
10401245Bglu18_mblood glucose level 18 (mouse)Not determined582838468116838597Mouse
13464242Ahl17_mage related hearing loss, early onset 17 (mouse)582838468116838597Mouse
10043958Chldq12_mcholesterol and HDL QTL 12 (mouse)Not determined587386871121387065Mouse
1301126Bwem1_mbody weight day 30 males 1 (mouse)Not determined587386871121387065Mouse
13464241Ahl18_mage related hearing loss, early onset 18 (mouse)587386871121387065Mouse
1300801Drb2_mdopamine receptor binding 2 (mouse)Not determined587386871121387065Mouse
1301399Cpfd3_mcerebellum pattern fissures (mouse)Not determined587386871121387065Mouse
1357725Eae39_mexperimental allergic encephalomyelitis 39 (mouse)Not determined589418876118864028Mouse
1300968Skts4_mskin tumor susceptibility 4 (mouse)Not determined589418876124238239Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
11049562Lmr24f_mleishmaniasis resistance 24f (mouse)590320962124321041Mouse
1301457Cfsw2_mcystic fibrosis survival to weaning 2 (mouse)Not determined590561006124561151Mouse
1300993Hycdc_mhypercapnic duty cycle (mouse)Not determined590561006124561151Mouse
9587780Afw16_mabdominal fat weight QTL 16 (mouse)Not determined592830166126830285Mouse
1301974Chab7_mcholesterol absorption 7 (mouse)Not determined595233214129233330Mouse
1357644Egrd1_mearly growth rate, direct effect 1 (mouse)Not determined595434580129434786Mouse
10402486Dipa1_mdrug induced psychomotor activation 1 (mouse)Not determined595465549129465722Mouse
13464244Ahl19_mage related hearing loss, early onset 19 (mouse)595465549129465722Mouse
1558774Lith17_mlithogenic gene 17 (mouse)Not determined595465549129465722Mouse
1300940Actd3_mactivity-distance traveled 3 (mouse)Not determined596320385130320533Mouse
1300659Pcd8ts1_mp-glycoprotein positive CD8 T cell subset 1 (mouse)Not determined597021753131021986Mouse
1301858Smdq1_msegregation of mitochondrial DNA QTL 1 (mouse)Not determined597021753131021986Mouse
1301042Elmaz1_melevated maze behavior 1 (mouse)Not determined598019649116876624Mouse
4141519Hmtb5_mhemostasis and thrombosis bleeding time 5 (mouse)Not determined99949422126882944Mouse
12904945Tammq2_mtibialis anterior muscle mass QTL 2 (mouse)5100665965134665965Mouse
12904959Smmq1_msoleus muscle mass QTL 1 (mouse)5100665965134665965Mouse
12859290Criq2_mCitrobacter rodentium infection QTL 2 (mouse)5101332579135332579Mouse
1301624Aevm2_mautoimmune extremity vasculitis in MRL mice 2 (mouse)Not determined5101863832135864028Mouse
14746986Manh58_mmandible shape 58 (mouse)5102446283136446283Mouse
11532736Sluc33b_msusceptibility to lung cancer 33b (mouse)5102945037136945196Mouse
11528550Sluc33_msusceptibility to lung cancer 33 (mouse)5104386871120711986Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
4141139Hmtb4_mhemostasis and thrombosis rebleeding time 4 (mouse)Not determined108762509126882944Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
4141652Mrdq2_mmodifier of retinal degeneration QTL 2 (mouse)Not determined110253106118093673Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1357662Lprq4_mlipoprotein QTL 4 (mouse)Not determined5114021753129632606Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse

Markers in Region
AW743423  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385116,409,116 - 116,409,370UniSTSGRCm38
MGSCv375116,859,125 - 116,859,379UniSTSGRCm37
Celera5113,506,207 - 113,506,461UniSTS
Cytogenetic Map5FUniSTS
cM Map559.0UniSTS
Whitehead/MRC_RH51426.89UniSTS
RH136226  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385116,408,593 - 116,408,791UniSTSGRCm38
MGSCv375116,858,602 - 116,858,800UniSTSGRCm37
Celera5113,505,684 - 113,505,882UniSTS
Cytogenetic Map5FUniSTS
cM Map559.0UniSTS
AW413033  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385116,408,811 - 116,408,944UniSTSGRCm38
MGSCv375116,858,820 - 116,858,953UniSTSGRCm37
Celera5113,505,902 - 113,506,035UniSTS
Cytogenetic Map5FUniSTS
cM Map559.0UniSTS
Whitehead/MRC_RH51425.26UniSTS
UniSTS:235285  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385116,408,911 - 116,409,081UniSTSGRCm38
MGSCv375116,858,920 - 116,859,090UniSTSGRCm37
Celera5113,506,002 - 113,506,172UniSTS
Cytogenetic Map5FUniSTS
cM Map559.0UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000036991   ⟹   ENSMUSP00000037007
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5116,546,550 - 116,560,923 (-)Ensembl
GRCm38.p6 Ensembl5116,408,491 - 116,422,864 (-)Ensembl
RefSeq Acc Id: ENSMUST00000133335
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5116,546,999 - 116,553,951 (-)Ensembl
GRCm38.p6 Ensembl5116,408,940 - 116,415,892 (-)Ensembl
RefSeq Acc Id: NM_030704   ⟹   NP_109629
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395116,546,550 - 116,560,923 (-)NCBI
GRCm385116,408,491 - 116,422,864 (-)NCBI
MGSCv375116,858,504 - 116,872,873 (-)RGD
Celera5113,505,586 - 113,520,087 (-)RGD
cM Map5 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_109629 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF65563 (Get FASTA)   NCBI Sequence Viewer  
  AAG00233 (Get FASTA)   NCBI Sequence Viewer  
  AAH11219 (Get FASTA)   NCBI Sequence Viewer  
  BAB23778 (Get FASTA)   NCBI Sequence Viewer  
  EDL19828 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000037007
  ENSMUSP00000037007.5
GenBank Protein Q9JK92 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_109629   ⟸   NM_030704
- UniProtKB: Q9JK92 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000037007   ⟸   ENSMUST00000036991
Protein Domains
sHSP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9JK92-F1-model_v2 AlphaFold Q9JK92 1-196 view protein structure

Promoters
RGD ID:6887792
Promoter ID:EPDNEW_M7347
Type:multiple initiation site
Name:Hspb8_1
Description:Mus musculus heat shock protein 8 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385116,422,866 - 116,422,926EPDNEW
RGD ID:6837726
Promoter ID:MM_KWN:43724
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000034850
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365116,865,401 - 116,865,901 (-)MPROMDB
RGD ID:6837727
Promoter ID:MM_KWN:43725
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:OTTMUST00000034849
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365116,872,166 - 116,873,137 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2135756 AgrOrtholog
Ensembl Genes ENSMUSG00000041548 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000036991 ENTREZGENE
  ENSMUST00000036991.5 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.790 UniProtKB/Swiss-Prot
InterPro A-crystallin/Hsp20_dom UniProtKB/Swiss-Prot
  Alpha-crystallin/HSP UniProtKB/Swiss-Prot
  HSP20-like_chaperone UniProtKB/Swiss-Prot
  HSPB8 UniProtKB/Swiss-Prot
  HspB8_ACD UniProtKB/Swiss-Prot
KEGG Report mmu:80888 UniProtKB/Swiss-Prot
MGD MGI:2135756 ENTREZGENE
NCBI Gene 80888 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN BETA-8 UniProtKB/Swiss-Prot
  PTHR46906 UniProtKB/Swiss-Prot
Pfam HSP20 UniProtKB/Swiss-Prot
PhenoGen Hspb8 PhenoGen
PRINTS ACRYSTALLIN UniProtKB/Swiss-Prot
PROSITE SHSP UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49764 UniProtKB/Swiss-Prot
UniProt HSPB8_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE