Nt5e (5' nucleotidase, ecto) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nt5e (5' nucleotidase, ecto) Mus musculus
Analyze
Symbol: Nt5e
Name: 5' nucleotidase, ecto
RGD ID: 62249
MGI Page MGI
Description: Enables 5'-nucleotidase activity. Involved in calcium ion homeostasis; inhibition of non-skeletal tissue mineralization; and purine ribonucleotide catabolic process. Acts upstream of or within adenosine biosynthetic process and negative regulation of inflammatory response. Located in plasma membrane. Is active in external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and musculoskeletal system. Human ortholog(s) of this gene implicated in hereditary arterial and articular multiple calcification syndrome. Orthologous to human NT5E (5'-nucleotidase ecto).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 2210401F01Rik; 5'-deoxynucleotidase; 5'-NT; 5'-nucleotidase; AI447961; CD73; ecto-5'-nucleotidase; eNT; IMP-specific 5'-nucleotidase; NT; Nt5; thymidylate 5'-phosphatase
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39988,209,662 - 88,254,142 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl988,209,250 - 88,254,145 (+)EnsemblGRCm39 Ensembl
GRCm38988,327,609 - 88,372,089 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl988,327,197 - 88,372,092 (+)EnsemblGRCm38mm10GRCm38
MGSCv37988,222,447 - 88,266,927 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36988,125,533 - 88,169,982 (+)NCBIMGSCv36mm8
Celera985,354,734 - 85,399,137 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map947.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP,ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrobenzenesulfonic acid  (EXP)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3,4-dichloroaniline  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
adenosine  (EXP)
ADP  (ISO)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
antimycin A  (EXP)
aripiprazole  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-naphthoflavone  (ISO)
betalain  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bortezomib  (ISO)
bucladesine  (ISO)
buspirone  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
cerium trichloride  (EXP)
chloropicrin  (ISO)
choline  (EXP)
ciguatoxin CTX1B  (EXP)
cis-caffeic acid  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
crocidolite asbestos  (EXP,ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP,ISO)
diclofenac  (EXP)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
dioxygen  (EXP,ISO)
disulfiram  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
furan  (ISO)
genistein  (EXP,ISO)
gentamycin  (ISO)
glafenine  (ISO)
homocysteine  (EXP)
hydrogen cyanide  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
medroxyprogesterone acetate  (ISO)
mercury dibromide  (ISO)
mercury dichloride  (ISO)
methapyrilene  (ISO)
methylarsonic acid  (EXP)
methylisothiazolinone  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (ISO)
nickel atom  (ISO)
nimesulide  (EXP,ISO)
nitrites  (EXP)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
potassium cyanide  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
quercetin  (EXP,ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP)
sodium dichromate  (EXP,ISO)
sotorasib  (ISO)
streptozocin  (EXP)
temozolomide  (ISO)
tenofovir disoproxil fumarate  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP,ISO)
thalidomide  (EXP)
thioacetamide  (EXP,ISO)
trametinib  (ISO)
trans-caffeic acid  (ISO)
trichostatin A  (ISO)
triptonide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
troglitazone  (EXP)
uranium atom  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
withaferin A  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine. Barsotti C, etal., J Biol Chem. 2005 Apr 8;280(14):13465-9. Epub 2005 Feb 6.
2. Neurotrophin-5: a novel neurotrophic factor that activates trk and trkB. Berkemeier LR, etal., Neuron 1991 Nov;7(5):857-66.
3. Dynamic changes in the expression pattern of ecto-5'-nucleotidase in the rat model of cortical stab injury. Bjelobaba I, etal., J Neurosci Res. 2011 Jun;89(6):862-73. doi: 10.1002/jnr.22599. Epub 2011 Feb 17.
4. Ontogenetic profile of ectonucleotidase activities from brain synaptosomes of pilocarpine-treated rats. de Paula Cognato G, etal., Int J Dev Neurosci. 2005 Dec;23(8):703-9. Epub 2005 Nov 4.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. Ectonucleotidase and acetylcholinesterase activities in synaptosomes from the cerebral cortex of streptozotocin-induced diabetic rats and treated with resveratrol. Schmatz R, etal., Brain Res Bull. 2009 Dec 16;80(6):371-6. Epub 2009 Aug 31.
Additional References at PubMed
PMID:7493409   PMID:8103780   PMID:8224905   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11375348   PMID:12477932   PMID:14681479   PMID:15319286   PMID:15343381   PMID:15358667  
PMID:15583013   PMID:16141072   PMID:16141073   PMID:16272299   PMID:16525161   PMID:16547283   PMID:16636171   PMID:16828810   PMID:17082591   PMID:17353435   PMID:17502665   PMID:17548651  
PMID:18034430   PMID:18256308   PMID:18263696   PMID:18322237   PMID:18353866   PMID:18391093   PMID:18424752   PMID:18591671   PMID:18600537   PMID:18607626   PMID:18804111   PMID:18838482  
PMID:18838560   PMID:18924612   PMID:19008478   PMID:19221436   PMID:19281303   PMID:20026782   PMID:20136797   PMID:20147550   PMID:20185832   PMID:20357256   PMID:20430891   PMID:20458493  
PMID:20548026   PMID:20709859   PMID:21063242   PMID:21267068   PMID:21270129   PMID:21292811   PMID:21346249   PMID:21469131   PMID:21537079   PMID:21543717   PMID:21593451   PMID:21653635  
PMID:21677750   PMID:21770045   PMID:21873635   PMID:21882189   PMID:21918191   PMID:21955554   PMID:22011440   PMID:22184407   PMID:22219293   PMID:22229268   PMID:22262774   PMID:22291183  
PMID:22348056   PMID:22396496   PMID:22406269   PMID:22421436   PMID:22423104   PMID:22514659   PMID:22540145   PMID:22666342   PMID:22761898   PMID:22826317   PMID:22967998   PMID:22977005  
PMID:22988118   PMID:23118501   PMID:23274765   PMID:23288168   PMID:23319349   PMID:23413361   PMID:23423261   PMID:23520507   PMID:23584256   PMID:23678122   PMID:23713028   PMID:23720442  
PMID:23729294   PMID:23749427   PMID:23776700   PMID:23825434   PMID:23843511   PMID:23956420   PMID:23964122   PMID:24066228   PMID:24262796   PMID:24266925   PMID:24464643   PMID:24493796  
PMID:24664100   PMID:24670982   PMID:24880143   PMID:24990899   PMID:25205101   PMID:25208846   PMID:25317558   PMID:25389034   PMID:25402681   PMID:25452548   PMID:25486201   PMID:25490556  
PMID:25564652   PMID:25644539   PMID:25681339   PMID:25805696   PMID:25877928   PMID:26150535   PMID:26201991   PMID:26258883   PMID:26261991   PMID:26331349   PMID:26432867   PMID:26506509  
PMID:26545615   PMID:26642367   PMID:26650818   PMID:26733167   PMID:26919582   PMID:26921334   PMID:26964090   PMID:27125672   PMID:27417582   PMID:27418188   PMID:27430240   PMID:27622332  
PMID:27628903   PMID:27732581   PMID:27793834   PMID:28060378   PMID:28087471   PMID:28192180   PMID:28288184   PMID:28325757   PMID:28349824   PMID:28376099   PMID:28404626   PMID:28432149  
PMID:28492224   PMID:28527294   PMID:28592560   PMID:28663494   PMID:28667437   PMID:28717030   PMID:28743609   PMID:28746349   PMID:28746783   PMID:28855210   PMID:29066514   PMID:29108754  
PMID:29377929   PMID:29451855   PMID:29663369   PMID:29725032   PMID:30097462   PMID:30201808   PMID:30291203   PMID:30635578   PMID:30676071   PMID:30926752   PMID:31093850   PMID:31279774  
PMID:31309149   PMID:31364375   PMID:31394204   PMID:31404305   PMID:31461341   PMID:31619062   PMID:31678157   PMID:31873309   PMID:31974050   PMID:31980601   PMID:31992567   PMID:32017200  
PMID:32970335   PMID:32999463   PMID:33121948   PMID:33328996   PMID:33343573   PMID:33516905   PMID:33584346   PMID:33681221   PMID:33683190   PMID:33727591   PMID:34184030   PMID:34216353  
PMID:34224862   PMID:34310891   PMID:34335618   PMID:34336823   PMID:34429546   PMID:34504490   PMID:34792724   PMID:35212809   PMID:35625624   PMID:35781329   PMID:35804900   PMID:35881490  
PMID:36330907   PMID:36361618   PMID:36409930   PMID:36445780   PMID:36539031   PMID:36628293   PMID:36720042   PMID:36946474   PMID:37178405   PMID:37180168   PMID:37611643   PMID:37616559  
PMID:37816827   PMID:38198186   PMID:38264660   PMID:38454449   PMID:38545102  


Genomics

Comparative Map Data
Nt5e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39988,209,662 - 88,254,142 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl988,209,250 - 88,254,145 (+)EnsemblGRCm39 Ensembl
GRCm38988,327,609 - 88,372,089 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl988,327,197 - 88,372,092 (+)EnsemblGRCm38mm10GRCm38
MGSCv37988,222,447 - 88,266,927 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36988,125,533 - 88,169,982 (+)NCBIMGSCv36mm8
Celera985,354,734 - 85,399,137 (+)NCBICelera
Cytogenetic Map9E3.1NCBI
cM Map947.24NCBI
NT5E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38685,450,083 - 85,495,784 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl685,449,584 - 85,495,791 (+)EnsemblGRCh38hg38GRCh38
GRCh37686,159,801 - 86,205,502 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36686,216,528 - 86,262,215 (+)NCBINCBI36Build 36hg18NCBI36
Build 34686,216,527 - 86,262,215NCBI
Celera686,586,482 - 86,632,679 (+)NCBICelera
Cytogenetic Map6q14.3NCBI
HuRef683,383,590 - 83,429,793 (+)NCBIHuRef
CHM1_1686,257,244 - 86,303,451 (+)NCBICHM1_1
T2T-CHM13v2.0686,666,882 - 86,712,587 (+)NCBIT2T-CHM13v2.0
Nt5e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8898,150,925 - 98,195,646 (+)NCBIGRCr8
mRatBN7.2889,271,046 - 89,314,918 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl889,270,696 - 89,314,881 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx894,940,630 - 94,984,431 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0893,139,844 - 93,183,642 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0890,998,970 - 91,042,930 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0895,969,002 - 96,012,733 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl895,968,652 - 96,012,696 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0895,464,591 - 95,508,322 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4893,591,630 - 93,635,481 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1893,610,734 - 93,654,911 (+)NCBI
Celera888,841,425 - 88,885,302 (+)NCBICelera
Cytogenetic Map8q31NCBI
Nt5e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541112,891,236 - 12,948,406 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541112,891,236 - 12,946,324 (+)NCBIChiLan1.0ChiLan1.0
NT5E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25105,532,410 - 105,584,140 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16103,429,147 - 103,478,675 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0683,333,428 - 83,379,585 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1686,615,409 - 86,661,594 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl686,615,409 - 86,661,601 (+)Ensemblpanpan1.1panPan2
NT5E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11245,491,028 - 45,520,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1245,491,733 - 45,518,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1245,289,507 - 45,334,783 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01246,244,000 - 46,289,219 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1246,243,992 - 46,289,217 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11245,577,415 - 45,622,655 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01245,506,318 - 45,551,536 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01245,693,314 - 45,738,560 (+)NCBIUU_Cfam_GSD_1.0
Nt5e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494680,624,771 - 80,673,677 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365105,797,212 - 5,846,124 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365105,797,218 - 5,846,118 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NT5E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl154,400,810 - 54,448,742 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1154,400,786 - 54,450,743 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2160,831,831 - 60,881,527 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NT5E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11310,115,591 - 10,162,178 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1310,116,161 - 10,160,414 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040186,303,608 - 186,348,855 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nt5e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247998,765,711 - 8,845,778 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247998,766,608 - 8,845,296 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nt5e
1738 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:561
Count of miRNA genes:408
Interacting mature miRNAs:464
Transcripts:ENSMUST00000034992
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142042Alpq3_malcohol preference QTL 3 (mouse)Not determined93730619798701707Mouse
4141224Dxmod_mdoxorubicin nephropathy modifier (mouse)Not determined49452421101406120Mouse
1301241Renf1_mrenal failure 1 (mouse)Not determined95203447899792481Mouse
12790990Tgl7_mtriglyceride 7 (mouse)95455996088559960Mouse
10043877Adip21_madiposity 21 (mouse)Not determined95643910890439255Mouse
1301803Stheal9_msoft tissue heal 9 (mouse)Not determined95902438793024534Mouse
1301172Fembrs6_mfemur breaking strength 6 (mouse)Not determined95902438793024534Mouse
1301456Adip5_madiposity 5 (mouse)Not determined95936994693370128Mouse
1300848Skull13_mskull morphology 13 (mouse)Not determined95936994693370128Mouse
5491195Mobq8_mmultigenic obesity QTL 8 (mouse)Not determined95936994693370128Mouse
13207569Tcq13_mtotal cholesterol QTL 13 (mouse)959897283109089068Mouse
1301611Lrnx3_mlearning contextual 3 (mouse)Not determined96214976796149881Mouse
4141833W10q13_mweight 10 weeks QTL 13 (mouse)Not determined63239711120191934Mouse
4141545Tailaq2_mtail length adjusted QTL 2 (mouse)Not determined63239711120191934Mouse
1357635Splq4_mspleen weight QTL 4 (mouse)Not determined963239711120191934Mouse
11081165Psl6_mpromotion susceptibility QTL 6 (mouse)96504119195522808Mouse
1301636Lith5_mlithogenic gene 5 (mouse)Not determined966089077100089175Mouse
10045638Heal29_mwound healing/regeneration 29 (mouse)Not determined967006220101006220Mouse
1357610Vtbt8_mvertebral trabecular bone trait 8 (mouse)Not determined968779563102779705Mouse
1301924Bmd10_mbone mineral density 10 (mouse)Not determined968779563102779705Mouse
1301302Pas4_mpulmonary adenoma susceptibility 4 (mouse)Not determined969121898103121973Mouse
10412174Habiir4_mhyperoxic acute lung injury imprinted region 4 (mouse)Not determined96926774798701707Mouse
1301621Hpic1_mhaloperidol-induced catalepsy 1 (mouse)Not determined969428566103428698Mouse
1301573Etohcta8_methanol conditioned taste aversion 8 (mouse)Not determined972859058106859205Mouse
10054068El8_mepilepsy 8 (mouse)Not determined972859058106859205Mouse
1301725Lifespan1_mlife span 1 (mouse)Not determined974250230108250378Mouse
1302065El1_mepilepsy 1 (mouse)Not determined975682646114303447Mouse
10054492El7_mepilepsy 7 (mouse)Not determined975682646114303447Mouse
1301869Tbbmd4_mtotal body bone mineral density 4 (mouse)Not determined976024387101406120Mouse
1301407Rapop2_mradiation-induced apoptosis 2 (mouse)Not determined976417989110418183Mouse
1301192Skts6_mskin tumor susceptibility 6 (mouse)Not determined978522698112522808Mouse
10401247Bglu14_mblood glucose level 14 (mouse)Not determined979279863113279941Mouse
1301732Char1_mP. chabaudi malaria resistance QTL 1 (mouse)Not determined981680321115680445Mouse
10766454Char10_mP. chabaudi malaria resistance QTL 10 (mouse)982792386116792481Mouse
1300884Sluc11_msusceptibility to lung cancer 11 (mouse)Not determined982792386116792481Mouse
1357461Idd2_minsulin dependent diabetes susceptibility 2 (mouse)Not determined982792386116792481Mouse
1301487Nociq1_mnociceptive sensitivity inflammatory QTL 1 (mouse)Not determined984406017118406120Mouse
10412180Msam3_mmuscle, skeletal, activity measure 3 (mouse)Not determined985779563108518385Mouse
1300549Bbaa17_mB. burgdorferi-associated arthritis 17 (mouse)Not determined986107600120107729Mouse
1302103Dob2_mdietary obesity 2 (mouse)Not determined986121898120118690Mouse
11251716Siim2_mstress induced immobility 2 (mouse)986625682120625682Mouse
12880422V25Dq6_mvitamin D inactive form serum level QTL 6 (mouse)987677199121677199Mouse

Markers in Region
AI447961  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38988,371,551 - 88,371,783UniSTSGRCm38
MGSCv37988,266,389 - 88,266,621UniSTSGRCm37
Celera985,398,599 - 85,398,831UniSTS
Cytogenetic Map9E3.2UniSTS
Whitehead/MRC_RH9955.8UniSTS
Nt5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38988,369,073 - 88,369,199UniSTSGRCm38
MGSCv37988,263,911 - 88,264,037UniSTSGRCm37
Celera985,396,121 - 85,396,247UniSTS
Cytogenetic Map9E3.2UniSTS
cM MapUN UniSTS
cM Map9 UniSTS
Nt5e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map9E3.2UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000034992   ⟹   ENSMUSP00000034992
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl988,209,250 - 88,254,145 (+)Ensembl
GRCm38.p6 Ensembl988,327,197 - 88,372,092 (+)Ensembl
RefSeq Acc Id: ENSMUST00000186789
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl988,209,671 - 88,213,272 (+)Ensembl
GRCm38.p6 Ensembl988,327,618 - 88,331,219 (+)Ensembl
RefSeq Acc Id: ENSMUST00000187166
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl988,209,686 - 88,249,897 (+)Ensembl
GRCm38.p6 Ensembl988,327,633 - 88,367,844 (+)Ensembl
RefSeq Acc Id: ENSMUST00000217134
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl988,237,740 - 88,240,056 (+)Ensembl
GRCm38.p6 Ensembl988,355,687 - 88,358,003 (+)Ensembl
RefSeq Acc Id: NM_011851   ⟹   NP_035981
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39988,209,662 - 88,254,142 (+)NCBI
GRCm38988,327,609 - 88,372,089 (+)ENTREZGENE
MGSCv37988,222,447 - 88,266,927 (+)RGD
Celera985,354,734 - 85,399,137 (+)RGD
cM Map9 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035981   ⟸   NM_011851
- Peptide Label: preproprotein
- UniProtKB: Q3U3S1 (UniProtKB/Swiss-Prot),   Q61503 (UniProtKB/Swiss-Prot),   Q0VEE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034992   ⟸   ENSMUST00000034992
Protein Domains
5'-Nucleotidase C-terminal   Calcineurin-like phosphoesterase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61503-F1-model_v2 AlphaFold Q61503 1-576 view protein structure

Promoters
RGD ID:6844888
Promoter ID:MM_KWN:58293
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:NM_011851,   UC009QYI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36988,222,201 - 88,222,701 (+)MPROMDB
RGD ID:8670378
Promoter ID:EPDNEW_M13219
Type:initiation region
Name:Nt5e_1
Description:Mus musculus 5' nucleotidase, ecto , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38988,327,640 - 88,327,700EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99782 AgrOrtholog
Ensembl Genes ENSMUSG00000032420 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034992 ENTREZGENE
  ENSMUST00000034992.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.21.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.90.780.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro 5'-Nucleotdase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5'-Nucleotdase_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5'-Nucleotdase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5_nucleotidase/apyrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Calcineurin-like_PHP_ApaH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Metallo-depent_PP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:23959 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99782 ENTREZGENE
NCBI Gene 23959 ENTREZGENE
PANTHER 5'-NUCLEOTIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11575 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 5_nucleotid_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Metallophos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB NT5E RGD
PhenoGen Nt5e PhenoGen
PRINTS APYRASEFAMLY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE 5_NUCLEOTIDASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  5_NUCLEOTIDASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55816 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 5NTD_MOUSE UniProtKB/Swiss-Prot
  Q0VEE0 ENTREZGENE, UniProtKB/TrEMBL
  Q3U3S1 ENTREZGENE
  Q61503 ENTREZGENE
UniProt Secondary Q3U3S1 UniProtKB/Swiss-Prot