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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62249
Species: Mus musculus
RGD Object: Gene
Symbol: Nt5e
Name: 5' nucleotidase, ecto
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nt5edecreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of NT5E mRNAPMID:17426115
Nt5eincreases expressionEXP 6480464CTDpirinixic acid results in increased expression of NT5E mRNAPMID:20813756 PMID:23811191
Nt5emultiple interactionsEXP 6480464CTD[pirinixic acid co-treated with PPARA] results in increased expression of NT5E mRNAPMID:20813756
Nt5eincreases expressionISONt5e (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of NT5E mRNAPMID:16940010
Nt5emultiple interactionsISONT5E (Homo sapiens)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of NT5E mRNAPMID:19710929
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