Gene: Mt1 (metallothionein 1)  Mus musculus Symbol: Mt1 Name: metallothionein 1 Description: ENCODES a protein that exhibits copper ion binding; metal ion binding; INVOLVED IN cellular metal ion homeostasis; cellular response to chromate; cellular response to zinc ion; ASSOCIATED WITH abnormal astrocyte morphology; abnormal circulating enzyme level; abnormal compact bone morphology; ASSOCIATED WITH Amyotrophic Lateral Sclerosis; Encephalomyelitis, Autoimmune, Experimental; Hyperoxia; FOUND IN cytosol; intracellular; lysosome; INTERACTS WITH (-)-selegiline; (2,4,5-trichlorophenoxy)acetic acid; (R)-lipoic acid Type: protein-coding RefSeq Status: VALIDATED Also known as: metallothionein-1; metallothionein-I; Mt-1; MT-I Orthologs: Homo sapiens : MT1A (metallothionein 1A)  HGNC Rattus norvegicus : Mt1a (metallothionein 1a) Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,089 - 94,180,327 + NCBI Mouse cM Map 8 46.34   NCBI Mouse Celera Assembly 8 98,511,203 - 98,512,441 + NCBI Mouse Genome Assembly Build 37 8 96,702,989 - 96,704,227 + NCBI Mouse Genome Assembly Build 36.1 8 96,703,127 - 96,704,224 + NCBI Mouse Cytogenetic Map 8 C5   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Acute-Phase Reaction   ISS RGD:3117 6484135 protein:increased expression:liver (rat) RGD   Amyotrophic Lateral Sclerosis   IEP   6484130 mRNA:increased expression:spinal cord (mouse) RGD   Cerebral Hemorrhage   ISS RGD:3117 2306905 mRNA:increased expression:cerebral cortex, striatum (rat) RGD   Encephalomyelitis, Autoimmune, Experimental   IEP   6484112 mRNA:increased expression:brain (mouse) RGD   Hyperoxia   IEP   6484136 mRNA:increased expression:lung (mouse) RGD   Kidney Diseases   ISS RGD:3117 6483854 mRNA:increased expression:kidney (rat) RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (-)-selegiline multiple interactions EXP   6480464 Selegiline inhibits the reaction [3-morpholino-sydnonimine results in increased expression of MT1 protein]; more ... CTD PMID:12880480 (2,4,5-trichlorophenoxy)acetic acid decreases expression EXP   6480464 2,4,5-Trichlorophenoxyacetic Acid results in decreased expression of MT1 mRNA CTD PMID:18579281 (R)-lipoic acid multiple interactions EXP   6480464 [Dietary Fats co-treated with Thioctic Acid] results in decreased expression of MT1 mRNA CTD PMID:18367378 1,2,4-trimethylbenzene increases expression ISO RGD:3117 6480464 pseudocumene results in increased expression of MT1A protein CTD PMID:17337753 1,4-benzoquinone increases expression EXP   6480464 benzoquinone results in increased expression of MT1 mRNA CTD PMID:14998373 1,4-dithiothreitol multiple interactions EXP   6480464 Dithiothreitol results in increased reduction of [MT1 protein binds to Zinc] CTD PMID:22001350 1-naphthyl isothiocyanate increases expression ISO RGD:3117 6480464 1-Naphthylisothiocyanate results in increased expression of MT1A mRNA CTD PMID:18289764 17alpha-ethynylestradiol decreases expression EXP   6480464 Ethinyl Estradiol results in decreased expression of MT1 mRNA CTD PMID:17555576 17alpha-ethynylestradiol increases expression ISO RGD:3117 6480464 Ethinyl Estradiol results in increased expression of MT1A mRNA CTD PMID:20186393 17alpha-ethynylestradiol decreases expression ISO RGD:3117 6480464 Ethinyl Estradiol results in decreased expression of MT1A mRNA CTD PMID:17557909 PMID:15834898 17alpha-ethynylestradiol decreases expression ISO RGD:3117 6480464 Ethinyl Estradiol results in decreased expression of MT1A mRNA CTD PMID:15834898 PMID:17557909 17beta-estradiol increases expression ISO RGD:737231 6480464 Estradiol results in increased expression of MT1A mRNA CTD PMID:19153601 17beta-estradiol decreases expression ISO RGD:737231 6480464 Estradiol results in decreased expression of MT1A mRNA CTD PMID:17982697 17beta-estradiol multiple interactions ISO RGD:737231 6480464 [Parathion co-treated with Estradiol] results in decreased expression of MT1A mRNA CTD PMID:17982697 17beta-estradiol affects expression ISO RGD:737231 6480464 Estradiol affects the expression of MT1A mRNA CTD PMID:22574217 17beta-estradiol decreases expression ISO RGD:3117 6480464 Estradiol results in decreased expression of MT1A mRNA CTD PMID:22127542 17beta-estradiol multiple interactions ISO RGD:3117 6480464 11-fluoro-7-(14,14,15,15-pentafluoro-6-methyl-10-thia-6-azapentadecyl)estra-1,3-5(10)-triene-3,17-diol inhibits the reaction [Estradiol results in decreased expression of MT1A mRNA] CTD PMID:22127542 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP   6480464 Tetrachlorodibenzodioxin results in decreased expression of MT1 mRNA CTD PMID:15667827 PMID:18372398 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP   6480464 Tetrachlorodibenzodioxin results in decreased expression of MT1A mRNA CTD PMID:23238561 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:11521753 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP   6480464 Tetrachlorodibenzodioxin affects the expression of MT1 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:11521753 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:16114106 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin affects the expression of MT1A mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:11521753 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:21041162 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:18178546 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:18295293 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:18163543 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:16054898 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:16114106 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:18465118 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:18295293 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP   6480464 Tetrachlorodibenzodioxin results in decreased expression of MT1 mRNA CTD PMID:18372398 PMID:15667827 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A protein CTD PMID:11521753 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:737231 6480464 Tetrachlorodibenzodioxin results in decreased expression of MT1A mRNA CTD PMID:16039398 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:3117 6480464 Tetrachlorodibenzodioxin results in increased expression of MT1A mRNA CTD PMID:18465118 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP   6480464 Tetrachlorodibenzodioxin results in increased expression of MT1 mRNA CTD PMID:18163543 more ... 2,4-dinitrotoluene affects expression ISO RGD:3117 6480464 2,4-dinitrotoluene affects the expression of MT1A mRNA CTD PMID:21346803 2-acetamidofluorene multiple interactions ISO RGD:3117 6480464 Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein] CTD PMID:15565650 2-acetamidofluorene increases expression ISO RGD:3117 6480464 2-Acetylaminofluorene results in increased expression of MT1A protein CTD PMID:15565650 2-butoxyethanol increases expression EXP   6480464 n-butoxyethanol results in increased expression of MT1 mRNA CTD PMID:19812364 2-nitrofluorene decreases expression ISO RGD:3117 6480464 2-nitrofluorene results in decreased expression of MT1A mRNA CTD PMID:15890375 PMID:14600272 2-nitrofluorene decreases expression ISO RGD:3117 6480464 2-nitrofluorene results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 3,4-methylenedioxymethamphetamine increases expression EXP   6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of MT1 protein; more ... CTD PMID:15306638 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP   6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MT1 mRNA CTD PMID:16054899 3H-1,2-dithiole-3-thione decreases expression ISO RGD:3117 6480464 1,2-dithiol-3-thione results in decreased expression of MT1A mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane affects expression EXP   6480464 4,4'-diaminodiphenylmethane affects the expression of MT1 mRNA CTD PMID:18648102 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression ISO RGD:3117 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT1A mRNA CTD PMID:15890375 PMID:14600272 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression ISO RGD:3117 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 4-hydroxynon-2-enal increases expression EXP   6480464 4-hydroxy-2-nonenal results in increased expression of MT1 mRNA CTD PMID:20979157 5-(2-methylpiperazine-1-sulfonyl)isoquinoline decreases expression EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased expression of MT1 mRNA CTD PMID:11551972 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA] CTD PMID:15142038 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA] CTD PMID:11551972 PMID:15142038 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Copper results in increased activity of MT1 promoter] CTD PMID:14576086 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 acetazolamide decreases expression EXP   6480464 Acetazolamide results in decreased expression of MT1 mRNA CTD PMID:19274763 acetohydrazide increases expression EXP   6480464 acetylhydrazine results in increased expression of MT1 mRNA CTD PMID:15282401 acetylsalicylic acid increases expression ISO RGD:3117 6480464 Aspirin results in increased expression of MT1A mRNA CTD PMID:12800193 acetylsalicylic acid multiple interactions EXP   6480464 Aspirin inhibits the reaction [Copper results in increased activity of MT1 promoter] CTD PMID:14576086 aflatoxin B1 decreases expression ISO RGD:3117 6480464 Aflatoxin B1 results in decreased expression of MT1A mRNA CTD PMID:15890375 PMID:14600272 aflatoxin B1 increases expression ISO RGD:737231 6480464 Aflatoxin B1 results in increased expression of MT1A mRNA CTD PMID:22100608 aflatoxin B1 decreases expression ISO RGD:3117 6480464 Aflatoxin B1 results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:15890375 aldosterone increases expression ISO RGD:3117 6480464 Aldosterone results in increased expression of MT1A mRNA CTD PMID:19333130 aldosterone multiple interactions ISO RGD:3117 6480464 Spironolactone inhibits the reaction [[Aldosterone co-treated with Sodium Chloride co-treated with Potassium Chloride] results in increased expression of MT1A protein] CTD PMID:17616752 aldosterone multiple interactions ISO RGD:3117 6480464 Amlodipine inhibits the reaction [Aldosterone results in increased expression of MT1A mRNA]; more ... CTD PMID:19333130 amlodipine multiple interactions ISO RGD:3117 6480464 Amlodipine inhibits the reaction [Aldosterone results in increased expression of MT1A mRNA] CTD PMID:19333130 ammonium chloride affects expression ISO RGD:3117 6480464 Ammonium Chloride affects the expression of MT1A mRNA CTD PMID:16483693 Aroclor 1254 increases expression ISO RGD:3117 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of MT1A mRNA CTD PMID:18178546 arsenic atom affects binding ISO RGD:737231 6480464 Arsenic binds to MT1A protein CTD PMID:16984198 arsenic atom increases expression ISO RGD:737231 6480464 Arsenic results in increased expression of MT1A mRNA CTD PMID:17409696 arsenic atom affects response to substance EXP   6480464 MT1 protein affects the susceptibility to Arsenic CTD PMID:10828279 arsenic atom decreases expression ISO RGD:737231 6480464 Arsenic results in decreased expression of MT1A mRNA CTD PMID:17637929 arsenic trichloride multiple interactions EXP   6480464 arsenic trichloride promotes the reaction [MTF1 protein binds to MT1 protein]; more ... CTD PMID:19276070 arsenic trichloride increases expression EXP   6480464 arsenic trichloride results in increased expression of MT1 mRNA CTD PMID:19276070 arsenite(3-) multiple interactions ISO RGD:737231 6480464 arsenite promotes the reaction [Dietary Fats results in decreased expression of MT1 mRNA] CTD PMID:18296743 arsenite(3-) increases expression ISO RGD:3117 6480464 arsenite results in increased expression of MT1A mRNA CTD PMID:1493605 arsenite(3-) increases expression EXP   6480464 arsenite results in increased expression of MT1 mRNA CTD PMID:19933842 PMID:18991936 arsenite(3-) increases expression EXP   6480464 arsenite results in increased expression of MT1 mRNA CTD PMID:18991936 PMID:19933842 bacitracin increases expression ISO RGD:3117 6480464 Bacitracin results in increased expression of MT1A mRNA CTD PMID:18289764 benzene affects expression ISO RGD:3117 6480464 Benzene affects the expression of MT1A mRNA CTD PMID:15878777 benzo[a]pyrene multiple interactions ISO RGD:737231 6480464 Benzo(a)pyrene promotes the reaction [Arecoline results in increased expression of MT1A mRNA] CTD PMID:17418620 benzo[a]pyrene increases expression ISO RGD:737231 6480464 Benzo(a)pyrene results in increased expression of MT1A mRNA CTD PMID:21871943 benzo[a]pyrene increases expression EXP   6480464 Benzo(a)pyrene results in increased expression of MT1 mRNA CTD PMID:21569818 benzo[a]pyrene decreases expression EXP   6480464 Benzo(a)pyrene results in decreased expression of MT1 mRNA CTD PMID:19770486 benzo[a]pyrene multiple interactions EXP   6480464 [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of MT1 mRNA CTD PMID:21715664 benzo[a]pyrene decreases expression ISO RGD:737231 6480464 Benzo(a)pyrene results in decreased expression of MT1A mRNA CTD PMID:20064835 benzoic acid increases expression ISO RGD:737231 6480464 Benzoic Acid results in increased expression of MT1A mRNA CTD PMID:20491607 bis(2-ethylhexyl) phthalate decreases expression EXP   6480464 Diethylhexyl Phthalate results in decreased expression of MT1 mRNA CTD PMID:15294341 bis(2-ethylhexyl) phthalate increases expression EXP   6480464 Diethylhexyl Phthalate results in increased expression of MT1 mRNA CTD PMID:19850644 PMID:15294341 bis(2-ethylhexyl) phthalate increases expression EXP   6480464 Diethylhexyl Phthalate results in increased expression of MT1 protein CTD PMID:15294341 bis(2-ethylhexyl) phthalate increases expression EXP   6480464 Diethylhexyl Phthalate results in increased expression of MT1 mRNA CTD PMID:15294341 PMID:19850644 bisphenol A multiple interactions EXP   6480464 bisphenol A inhibits the reaction [Cadmium results in increased expression of MT1 mRNA]; more ... CTD PMID:11771854 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:17409696 more ... cadmium atom affects abundance ISO RGD:737231 6480464 MT1A gene polymorphism affects the abundance of Cadmium CTD PMID:22995156 cadmium atom multiple interactions ISO RGD:737231 6480464 MT1A gene polymorphism affects the abundance of and affects the susceptibility to Cadmium; more ... CTD PMID:22995156 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12716893 more ... cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12716893 more ... cadmium atom affects binding EXP   6480464 MT1 protein binds to Cadmium CTD PMID:22001350 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:11430474 more ... cadmium atom multiple interactions EXP   6480464 [ferric nitrilotriacetate co-treated with Hydrogen Peroxide] inhibits the reaction [MT1 protein binds to Cadmium] CTD PMID:22001350 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A CTD PMID:12974610 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:22562489 more ... cadmium atom affects binding ISO RGD:737231 6480464 MT1A protein binds to Cadmium CTD PMID:22242602 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12716893 more ... cadmium atom increases expression EXP   6480464 Cadmium results in increased expression of MT1 mRNA CTD PMID:10605938 more ... cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:11430474 more ... cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:16827180 more ... cadmium atom increases expression EXP   6480464 Cadmium results in increased expression of MT1 mRNA CTD PMID:11771854 PMID:11163336 cadmium atom affects binding ISO RGD:737231 6480464 Cadmium binds to MT1A protein CTD PMID:20329713 cadmium atom decreases response to substance ISO RGD:3117 6480464 MT1A protein results in decreased susceptibility to Cadmium CTD PMID:17443291 PMID:16516943 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A protein CTD PMID:17443291 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12854162 more ... cadmium atom affects expression ISO RGD:3117 6480464 Cadmium affects the expression of MT1A protein; more ... CTD PMID:12140172 cadmium atom decreases expression ISO RGD:3117 6480464 Cadmium results in decreased expression of MT1A mRNA CTD PMID:14694715 cadmium atom affects binding ISO RGD:3117 6480464 Cadmium binds to MT1A protein CTD PMID:8924612 cadmium atom multiple interactions ISO RGD:3117 6480464 1,1-diethyl-2-hydroxy-2-nitrosohydrazine inhibits the reaction [Cadmium binds to MT1A protein] CTD PMID:8924612 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A protein CTD PMID:15664440 cadmium atom multiple interactions ISO RGD:737231 6480464 chromium hexavalent ion inhibits the reaction [Cadmium results in increased expression of MT1A mRNA] CTD PMID:12716893 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12716893 more ... cadmium atom multiple interactions ISO RGD:3117 6480464 Quercetin promotes the reaction [Cadmium results in increased expression of MT1 mRNA] CTD PMID:16226777 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1 mRNA CTD PMID:16226777 cadmium atom multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]; more ... CTD PMID:16568437 cadmium atom increases expression EXP   6480464 Cadmium results in increased expression of MT1 protein CTD PMID:11771854 cadmium atom increases expression EXP   6480464 Cadmium results in increased expression of MT1 mRNA CTD PMID:11163336 PMID:11771854 cadmium atom multiple interactions EXP   6480464 bisphenol A inhibits the reaction [Cadmium results in increased expression of MT1 protein]; more ... CTD PMID:11771854 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:11311571 more ... cadmium atom multiple interactions EXP   6480464 MTF1 protein affects the reaction [Cadmium results in increased expression of MT1 mRNA] CTD PMID:18458062 cadmium atom multiple interactions EXP   6480464 USF1 affects the reaction [Cadmium results in increased expression of MT1 mRNA] CTD PMID:10605938 cadmium atom multiple interactions ISO RGD:3117 6480464 [Butyrates co-treated with Cadmium] results in increased expression of MT1A mRNA; more ... CTD PMID:1597404 cadmium atom increases expression EXP   6480464 Cadmium results in increased expression of MT1 mRNA CTD PMID:10605938 more ... cadmium atom multiple interactions ISO RGD:3117 6480464 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene promotes the reaction [Cadmium results in increased expression of MT1A mRNA] CTD PMID:11311571 cadmium atom increases expression ISO RGD:737231 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:12716893 more ... cadmium atom decreases response to substance ISO RGD:3117 6480464 MT1A protein results in decreased susceptibility to Cadmium CTD PMID:16516943 PMID:17443291 cadmium atom increases expression ISO RGD:3117 6480464 Cadmium results in increased expression of MT1A mRNA CTD PMID:17327699 more ... cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A protein CTD PMID:17443291 PMID:15249216 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:10952993 more ... cadmium dichloride multiple interactions EXP   6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form] promotes the reaction [Cadmium Chloride results in increased expression of GSTA2 mRNA]; more ... CTD PMID:22914987 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:10952993 more ... cadmium dichloride multiple interactions EXP   6480464 Dichlororibofuranosylbenzimidazole inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:15142038 cadmium dichloride multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 PMID:15142038 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A CTD PMID:17483498 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:10952993 more ... cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:15454312 more ... cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:10952993 more ... cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:15454312 more ... cadmium dichloride affects expression ISO RGD:3117 6480464 Cadmium Chloride affects the expression of MT1A mRNA CTD PMID:15795064 PMID:22110744 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:11551972 more ... cadmium dichloride affects expression EXP   6480464 Cadmium Chloride affects the expression of MT1 mRNA CTD PMID:16842966 cadmium dichloride multiple interactions EXP   6480464 MT1 affects the reaction [Cadmium Chloride results in decreased expression of BRCA2 mRNA]; more ... CTD PMID:11958953 cadmium dichloride multiple interactions EXP   6480464 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 cadmium dichloride multiple interactions EXP   6480464 MT1 gene mutant form promotes the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA] CTD PMID:11051100 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:21297351 more ... cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:15454312 PMID:17327699 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:19276070 more ... cadmium dichloride multiple interactions ISO RGD:3117 6480464 Zinc inhibits the reaction [Cadmium Chloride results in increased expression of MT1A mRNA] CTD PMID:20096345 cadmium dichloride multiple interactions ISO RGD:3117 6480464 lead acetate promotes the reaction [Cadmium Chloride results in increased expression of MT1A mRNA] CTD PMID:19096765 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:20186393 more ... cadmium dichloride affects expression ISO RGD:3117 6480464 Cadmium Chloride affects the expression of MT1A mRNA CTD PMID:22110744 PMID:15795064 cadmium dichloride multiple interactions EXP   6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of MT1 mRNA CTD PMID:19840844 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:17499415 more ... cadmium dichloride decreases response to substance ISO RGD:3117 6480464 MT1A protein results in decreased susceptibility to Cadmium Chloride CTD PMID:17443291 cadmium dichloride affects metabolic processing ISO RGD:3117 6480464 MT1A protein affects the metabolism of Cadmium Chloride CTD PMID:15249216 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A protein CTD PMID:15249216 PMID:17443291 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:17327699 PMID:15454312 cadmium dichloride affects expression ISO RGD:3117 6480464 Cadmium Chloride affects the expression of MT1A mRNA CTD PMID:15795064 cadmium dichloride decreases response to substance ISO RGD:737231 6480464 MT1A protein results in decreased susceptibility to Cadmium Chloride CTD PMID:11878821 cadmium dichloride increases expression ISO RGD:737231 6480464 Cadmium Chloride results in increased expression of MT1A protein CTD PMID:15788722 cadmium dichloride increases response to substance EXP   6480464 MT1 protein results in increased susceptibility to Cadmium Chloride CTD PMID:16150881 cadmium dichloride decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Cadmium Chloride CTD PMID:15795095 cadmium dichloride multiple interactions EXP   6480464 MT1 affects the susceptibility to [Cadmium Chloride co-treated with sodium arsenite] CTD PMID:10924798 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 protein CTD PMID:15964310 cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:19276070 more ... cadmium dichloride multiple interactions ISO RGD:3117 6480464 [Zinc Sulfate co-treated with Cadmium Chloride] results in increased expression of MT1A mRNA CTD PMID:2219126 cadmium dichloride increases expression ISO RGD:3117 6480464 Cadmium Chloride results in increased expression of MT1A mRNA CTD PMID:15454312 more ... cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:10952993 more ... cadmium dichloride increases expression EXP   6480464 Cadmium Chloride results in increased expression of MT1 mRNA CTD PMID:11171528 more ... cadmium sulfate multiple interactions EXP   6480464 cadmium sulfate affects the reaction [MTF1 affects the expression of MT1 mRNA] CTD PMID:16221973 carboplatin decreases expression ISO RGD:3117 6480464 Carboplatin results in decreased expression of MT1A mRNA CTD PMID:18172885 carrageenan multiple interactions EXP   6480464 [Methylnitrosourea co-treated with Carrageenan] results in increased expression of MT1 protein CTD PMID:15928667 cefaloridine decreases expression ISO RGD:3117 6480464 Cephaloridine results in decreased expression of MT1A mRNA CTD PMID:18172885 cerium trichloride increases expression EXP   6480464 cerous chloride results in increased expression of MT1 protein CTD PMID:15964310 cerium trichloride multiple interactions EXP   6480464 cerous chloride promotes the reaction [Zinc binds to MT1 protein] CTD PMID:16204935 chloroethene decreases expression EXP   6480464 Vinyl Chloride results in decreased expression of MT1 mRNA CTD PMID:18579281 chloroprene increases expression EXP   6480464 Chloroprene results in increased expression of MT1 mRNA CTD PMID:23125180 cholesterol multiple interactions EXP   6480464 [Cholesterol co-treated with 1,2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of MT1 mRNA CTD PMID:22129739 cholic acid increases expression EXP   6480464 Cholic Acid results in increased expression of MT1 mRNA CTD PMID:17521389 choline multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MT1 mRNA CTD PMID:20938992 chromium(6+) multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA] CTD PMID:18605988 PMID:21467744 chromium(6+) multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA]; more ... CTD PMID:21467744 chromium(6+) multiple interactions ISO RGD:737231 6480464 chromium hexavalent ion inhibits the reaction [Cadmium results in increased expression of MT1A mRNA]; more ... CTD PMID:12716893 ciguatoxin CTX1B affects expression EXP   6480464 Ciguatoxins affects the expression of MT1 mRNA CTD PMID:18353800 cis-ketoconazole increases expression ISO RGD:3117 6480464 Ketoconazole results in increased expression of MT1A mRNA CTD PMID:18289764 cisplatin increases response to substance EXP   6480464 MT1 protein results in increased susceptibility to Cisplatin CTD PMID:16150881 cisplatin increases expression ISO RGD:3117 6480464 Cisplatin results in increased expression of MT1A mRNA CTD PMID:18289764 PMID:22023808 cisplatin increases expression ISO RGD:3117 6480464 Cisplatin results in increased expression of MT1A mRNA CTD PMID:22023808 PMID:18289764 cisplatin decreases expression ISO RGD:3117 6480464 Cisplatin results in decreased expression of MT1A mRNA CTD PMID:18172885 cisplatin increases expression ISO RGD:737231 6480464 Cisplatin results in increased expression of MT1A mRNA CTD PMID:12680227 clofibrate multiple interactions EXP   6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of MT1 mRNA; more ... CTD PMID:17585979 clofibrate decreases expression ISO RGD:3117 6480464 Clofibrate results in decreased expression of MT1 mRNA CTD PMID:1280124 cobalt dichloride increases expression ISO RGD:3117 6480464 cobaltous chloride results in increased expression of MT1A mRNA CTD PMID:7626009 cobalt dichloride increases expression ISO RGD:3117 6480464 cobaltous chloride results in increased expression of MT1A mRNA CTD PMID:19278353 PMID:7626009 cobalt dichloride multiple interactions ISO RGD:3117 6480464 [Oxygen deficiency co-treated with cobaltous chloride] results in increased expression of MT1A mRNA CTD PMID:19278353 cobalt dichloride increases expression ISO RGD:3117 6480464 cobaltous chloride results in increased expression of MT1A mRNA CTD PMID:7626009 PMID:19278353 cobalt dichloride increases expression ISO RGD:3117 6480464 [cobaltous chloride results in increased expression of HIF1A protein] which results in increased expression of MT1A protein CTD PMID:21054399 cobalt dichloride decreases expression EXP   6480464 cobaltous chloride results in decreased expression of MT1 mRNA CTD PMID:21139344 copper atom increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:2231026 copper atom multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the abundance of Copper; more ... CTD PMID:14627437 copper atom increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:14627437 more ... copper atom increases activity EXP   6480464 Copper results in increased activity of MT1 promoter CTD PMID:14576086 copper atom multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Copper results in increased activity of MT1 promoter]; more ... CTD PMID:14576086 copper atom increases expression EXP   6480464 Copper results in increased expression of MT1 protein CTD PMID:17205981 copper atom increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:2231026 PMID:17205981 copper atom multiple interactions EXP   6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of MT1 mRNA CTD PMID:15467011 copper atom multiple interactions ISO RGD:737231 6480464 [MT1 protein co-treated with MT2 protein] affects the reaction [Copper results in increased expression of ANXA5 mRNA]; more ... CTD PMID:16629173 copper atom increases expression ISO RGD:3117 6480464 Copper results in increased expression of MT1A mRNA CTD PMID:15591161 copper atom affects expression ISO RGD:3117 6480464 Copper affects the expression of MT1A mRNA; more ... CTD PMID:12140172 copper atom multiple interactions EXP   6480464 [diamsar chelate results in decreased abundance of Copper] which affects the expression of MT1 mRNA CTD PMID:2231026 copper(0) increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:2231026 copper(0) multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the abundance of Copper; more ... CTD PMID:14627437 copper(0) increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:14627437 more ... copper(0) increases activity EXP   6480464 Copper results in increased activity of MT1 promoter CTD PMID:14576086 copper(0) multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Copper results in increased activity of MT1 promoter]; more ... CTD PMID:14576086 copper(0) increases expression EXP   6480464 Copper results in increased expression of MT1 protein CTD PMID:17205981 copper(0) increases expression EXP   6480464 Copper results in increased expression of MT1 mRNA CTD PMID:2231026 PMID:17205981 copper(0) multiple interactions EXP   6480464 [ATP7A gene mutant form results in increased abundance of Copper] which results in increased expression of MT1 mRNA CTD PMID:15467011 copper(0) multiple interactions ISO RGD:737231 6480464 [MT1 protein co-treated with MT2 protein] affects the reaction [Copper results in increased expression of ANXA5 mRNA]; more ... CTD PMID:16629173 copper(0) increases expression ISO RGD:3117 6480464 Copper results in increased expression of MT1A mRNA CTD PMID:15591161 copper(0) affects expression ISO RGD:3117 6480464 Copper affects the expression of MT1A mRNA; more ... CTD PMID:12140172 copper(0) multiple interactions EXP   6480464 [diamsar chelate results in decreased abundance of Copper] which affects the expression of MT1 mRNA CTD PMID:2231026 copper(2+) sulfate increases expression ISO RGD:737231 6480464 Copper Sulfate results in increased expression of MT1A mRNA CTD PMID:20599845 copper(2+) sulfate decreases expression EXP   6480464 Copper Sulfate results in decreased expression of MT1 mRNA CTD PMID:18579281 copper(2+) sulfate increases expression ISO RGD:737231 6480464 Copper Sulfate results in increased expression of MT1A mRNA CTD PMID:19549813 PMID:20599845 copper(2+) sulfate increases expression ISO RGD:3117 6480464 Copper Sulfate results in increased expression of MT1A mRNA CTD PMID:19679144 copper(2+) sulfate increases expression ISO RGD:737231 6480464 Copper Sulfate results in increased expression of MT1A mRNA CTD PMID:20599845 PMID:19549813 copper(II) chloride increases expression ISO RGD:737231 6480464 cupric chloride results in increased expression of MT1A mRNA CTD PMID:17211630 corticosterone increases expression ISO RGD:3117 6480464 Corticosterone results in increased expression of MT1A mRNA CTD PMID:15755911 coumarin increases expression ISO RGD:3117 6480464 coumarin results in increased expression of MT1A mRNA CTD PMID:18480146 curcumin increases expression ISO RGD:3117 6480464 Curcumin results in increased expression of MT1A mRNA CTD PMID:20229497 curcumin multiple interactions ISO RGD:3117 6480464 Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT1A mRNA] CTD PMID:20229497 cycloheximide multiple interactions EXP   6480464 Cycloheximide promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]; more ... CTD PMID:14998373 cycloheximide increases expression EXP   6480464 Cycloheximide results in increased expression of MT1 mRNA CTD PMID:19276070 cycloheximide multiple interactions EXP   6480464 Cycloheximide promotes the reaction [arsenic trichloride results in increased expression of MT1 mRNA]; more ... CTD PMID:19276070 cycloheximide increases expression EXP   6480464 Cycloheximide results in increased expression of MT1 mRNA CTD PMID:14998373 PMID:19276070 cytarabine decreases expression ISO RGD:737231 6480464 Cytarabine results in decreased expression of MT1A mRNA CTD PMID:21198554 D-glucose increases expression ISO RGD:3117 6480464 Glucose results in increased expression of MT1A mRNA CTD PMID:23056475 D-glucose multiple interactions ISO RGD:3117 6480464 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT1A mRNA]; more ... CTD PMID:23056475 daunorubicin increases expression ISO RGD:3117 6480464 Daunorubicin results in increased expression of MT1A mRNA; more ... CTD PMID:12204545 daunorubicin multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Daunorubicin results in increased expression of MT1A protein]; more ... CTD PMID:12204545 Delta(9)-tetrahydrocannabinol increases expression ISO RGD:737231 6480464 Tetrahydrocannabinol results in increased expression of MT1A mRNA CTD PMID:16039398 dexamethasone multiple interactions ISO RGD:3117 6480464 [Butyrates co-treated with Dexamethasone] results in increased expression of MT1A mRNA; more ... CTD PMID:1597404 dexamethasone increases expression ISO RGD:3117 6480464 Dexamethasone results in increased expression of MT1A mRNA CTD PMID:16962226 PMID:20032058 dexamethasone increases expression EXP   6480464 Dexamethasone results in increased expression of MT1 mRNA CTD PMID:21041162 dexamethasone increases expression ISO RGD:3117 6480464 Dexamethasone results in increased expression of MT1A mRNA CTD PMID:15851833 dexamethasone multiple interactions ISO RGD:3117 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of MT1A mRNA] CTD PMID:20032058 dexamethasone increases expression ISO RGD:3117 6480464 Dexamethasone results in increased expression of MT1A mRNA CTD PMID:20032058 PMID:16962226 dexamethasone multiple interactions EXP   6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MT1 mRNA CTD PMID:16054899 dexamethasone multiple interactions ISO RGD:3117 6480464 Dexamethasone inhibits the reaction [EGF protein results in increased expression of MT1A mRNA] CTD PMID:7705776 dexamethasone increases expression ISO RGD:3117 6480464 Dexamethasone results in increased expression of MT1A mRNA CTD PMID:16962226 more ... diarsenic trioxide increases expression ISO RGD:737231 6480464 arsenic trioxide results in increased expression of MT1A mRNA CTD PMID:19128835 diazoxide increases expression EXP   6480464 Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 diazoxide increases expression EXP   6480464 Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 PMID:21335049 dicoumarol multiple interactions EXP   6480464 Dicumarol inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 dicoumarol multiple interactions EXP   6480464 Dicumarol inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA] CTD PMID:11551972 PMID:15142038 dicoumarol multiple interactions EXP   6480464 Dicumarol inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA] CTD PMID:15142038 diethyl maleate increases expression ISO RGD:737231 6480464 diethyl maleate results in increased expression of MT1A mRNA CTD PMID:20491607 diethylstilbestrol increases expression ISO RGD:3117 6480464 Diethylstilbestrol results in increased expression of MT1A mRNA CTD PMID:15890375 diethylstilbestrol increases expression EXP   6480464 Diethylstilbestrol results in increased expression of MT1 mRNA CTD PMID:21041162 dimethylarsinic acid increases expression ISO RGD:3117 6480464 Cacodylic Acid results in increased expression of MT1A mRNA CTD PMID:16122865 dimethylarsinic acid increases expression EXP   6480464 Cacodylic Acid results in increased expression of MT1 mRNA CTD PMID:17441966 dioxygen increases expression ISO RGD:3117 6480464 Oxygen results in increased expression of MT1A mRNA CTD PMID:15680347 dioxygen multiple interactions ISO RGD:3117 6480464 [Oxygen deficiency co-treated with cobaltous chloride] results in increased expression of MT1A mRNA CTD PMID:19278353 dioxygen increases expression ISO RGD:3117 6480464 Oxygen deficiency results in increased expression of MT1A mRNA CTD PMID:19278353 diphenylcyclopropenone increases expression ISO RGD:737231 6480464 diphenylcyclopropenone results in increased expression of MT1A mRNA CTD PMID:20491607 diquat multiple interactions EXP   6480464 PROP1 protein affects the reaction [Diquat results in decreased expression of MT1 mRNA] CTD PMID:20826540 diquat decreases expression EXP   6480464 Diquat results in decreased expression of MT1 mRNA CTD PMID:20826540 disodium selenite increases expression ISO RGD:737231 6480464 Sodium Selenite results in increased expression of MT1A mRNA CTD PMID:18175754 disodium selenite multiple interactions EXP   6480464 Sodium Selenite inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 dopamine multiple interactions EXP   6480464 [MT1 co-treated with Dopamine] results in decreased abundance of semiquinone radicals CTD PMID:17910954 dopamine multiple interactions EXP   6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form co-treated with Mercuric Chloride] results in decreased abundance of Dopamine CTD PMID:18226494 doxorubicin increases expression EXP   6480464 Doxorubicin results in increased expression of MT1 mRNA CTD PMID:16243910 doxorubicin multiple interactions EXP   6480464 MT1 affects the reaction [Doxorubicin results in decreased expression of GPX1 protein]; more ... CTD PMID:21463615 doxorubicin decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Doxorubicin CTD PMID:21463615 doxorubicin multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the reaction [Glutathione affects the susceptibility to Doxorubicin]; more ... CTD PMID:20600803 doxorubicin multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin CTD PMID:20600803 PMID:21040762 doxorubicin multiple interactions EXP   6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of ADCY7 mRNA; more ... CTD PMID:21040762 doxorubicin decreases expression ISO RGD:3117 6480464 Doxorubicin results in decreased expression of MT1A mRNA CTD PMID:19915844 ethanol multiple interactions ISO RGD:3117 6480464 LEPR gene mutant form inhibits the reaction [Ethanol results in increased expression of MT1A mRNA]; more ... CTD PMID:15475485 ethanol increases expression EXP   6480464 Ethanol results in increased expression of MT1 mRNA CTD PMID:17637929 PMID:19167417 ethanol multiple interactions ISO RGD:3117 6480464 [Fish Oils co-treated with Ethanol] results in decreased expression of MT1A mRNA CTD PMID:17347304 ethanol increases expression EXP   6480464 Ethanol results in increased expression of MT1 mRNA CTD PMID:17637929 ethanol increases expression ISO RGD:3117 6480464 Ethanol results in increased expression of MT1A protein; more ... CTD PMID:17637929 ethanol decreases expression EXP   6480464 Ethanol results in decreased expression of MT1 protein CTD PMID:15920153 ethanol multiple interactions EXP   6480464 [Ethanol co-treated with Zinc Sulfate] results in increased expression of MT1 protein CTD PMID:15920153 ethanol increases expression ISO RGD:3117 6480464 Ethanol results in increased expression of MT1A mRNA; more ... CTD PMID:15475485 PMID:17637929 ethylenediaminetetraacetic acid multiple interactions EXP   6480464 Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]]; more ... CTD PMID:14998373 ferroheme b decreases response to substance ISO RGD:737231 6480464 MT1A protein results in decreased susceptibility to Heme CTD PMID:11878821 ferroheme b multiple interactions EXP   6480464 [Heme co-treated with HPX protein] affects the activity of MT1 promoter CTD PMID:11213479 folic acid multiple interactions ISO RGD:3117 6480464 Folic Acid inhibits the reaction [Homocysteine results in decreased expression of MT1A mRNA]; more ... CTD PMID:19641857 folic acid multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MT1 mRNA CTD PMID:20938992 fumonisin B1 decreases expression EXP   6480464 fumonisin B1 results in decreased expression of MT1 mRNA CTD PMID:16221962 furan decreases expression ISO RGD:3117 6480464 furan results in decreased expression of MT1A mRNA CTD PMID:15120968 gamma-hexachlorocyclohexane increases expression ISO RGD:3117 6480464 Lindane results in increased expression of MT1A mRNA CTD PMID:17785943 genistein multiple interactions EXP   6480464 Genistein inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA] CTD PMID:11551972 genistein increases expression EXP   6480464 Genistein results in increased expression of MT1 mRNA CTD PMID:11551972 genistein 7-O-beta-D-glucoside increases expression ISO RGD:737231 6480464 genistin analog results in increased expression of MT1A mRNA CTD PMID:16719502 glucose increases expression ISO RGD:3117 6480464 Glucose results in increased expression of MT1A mRNA CTD PMID:23056475 glucose multiple interactions ISO RGD:3117 6480464 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Glucose results in increased expression of MT1A mRNA]; more ... CTD PMID:23056475 glutathione increases expression ISO RGD:3117 6480464 Glutathione deficiency results in increased expression of MT1A mRNA CTD PMID:15345336 glutathione multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the reaction [Glutathione affects the susceptibility to Doxorubicin] CTD PMID:20600803 glycerol increases expression ISO RGD:737231 6480464 Glycerol results in increased expression of MT1A mRNA CTD PMID:20491607 griseofulvin increases expression EXP   6480464 Griseofulvin results in increased expression of MT1 mRNA CTD PMID:12735108 hexachlorobenzene increases expression ISO RGD:3117 6480464 Hexachlorobenzene results in increased expression of MT1A mRNA CTD PMID:15159207 hydrogen peroxide increases expression EXP   6480464 Hydrogen Peroxide results in increased expression of MT1 mRNA CTD PMID:14998373 hydrogen peroxide multiple interactions EXP   6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form] inhibits the reaction [Hydrogen Peroxide results in increased expression of ABCC1]; more ... CTD PMID:22914987 hydrogen peroxide multiple interactions EXP   6480464 [ferric nitrilotriacetate co-treated with Hydrogen Peroxide] inhibits the reaction [MT1 protein binds to Cadmium]; more ... CTD PMID:22001350 hydrogen peroxide multiple interactions EXP   6480464 MTF1 protein affects the reaction [Hydrogen Peroxide results in increased expression of MT1 mRNA] CTD PMID:14998373 hydroquinone increases expression EXP   6480464 hydroquinone results in increased expression of MT1 mRNA CTD PMID:14998373 hydroxycitronellal increases expression ISO RGD:737231 6480464 hydroxycitronellal results in increased expression of MT1A mRNA CTD PMID:20491607 iron atom multiple interactions ISO RGD:3117 6480464 Iron results in increased expression of and affects the localization of MT1A protein; more ... CTD PMID:17241390 iron atom increases expression ISO RGD:3117 6480464 Iron deficiency results in increased expression of MT1A mRNA CTD PMID:16629162 iron trichloride decreases response to substance ISO RGD:737231 6480464 MT1A protein results in decreased susceptibility to ferric chloride CTD PMID:11878821 isoprenaline increases expression EXP   6480464 Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 isoprenaline increases expression EXP   6480464 Isoproterenol results in increased expression of MT1 mRNA CTD PMID:20003209 PMID:21335049 kainic acid decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Kainic Acid CTD PMID:10947810 kainic acid increases expression ISO RGD:3117 6480464 Kainic Acid results in increased expression of MT1A mRNA CTD PMID:12692462 ketamine increases expression ISO RGD:3117 6480464 Ketamine results in increased expression of MT1A mRNA CTD PMID:20080153 L-ascorbic acid increases expression ISO RGD:3117 6480464 Ascorbic Acid results in increased expression of MT1A mRNA CTD PMID:15372504 L-methionine multiple interactions EXP   6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of MT1 mRNA CTD PMID:20938992 lead diacetate multiple interactions ISO RGD:3117 6480464 lead acetate promotes the reaction [Cadmium Chloride results in increased expression of MT1A mRNA] CTD PMID:19096765 lead diacetate increases expression EXP   6480464 lead acetate results in increased expression of MT1 mRNA CTD PMID:21335049 lead diacetate decreases response to substance EXP   6480464 MT1 results in decreased susceptibility to lead acetate CTD PMID:20600549 lipoic acid multiple interactions EXP   6480464 [Dietary Fats co-treated with Thioctic Acid] results in decreased expression of MT1 mRNA CTD PMID:18367378 LY294002 multiple interactions EXP   6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 LY294002 multiple interactions ISO RGD:737231 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:17363595 malonaldehyde increases expression ISO RGD:737231 6480464 Malondialdehyde results in increased expression of MT1A protein CTD PMID:15640275 maneb multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in decreased expression of MT1 mRNA CTD PMID:18386188 manganese(II) chloride decreases expression ISO RGD:3117 6480464 manganese chloride results in decreased expression of MT1A mRNA CTD PMID:12387356 mercury atom affects binding EXP   6480464 Mercury binds to MT1 protein CTD PMID:15603537 mercury atom affects abundance ISO RGD:737231 6480464 MT1A gene polymorphism affects the abundance of Mercury CTD PMID:19515364 mercury atom increases expression EXP   6480464 Mercury results in increased expression of MT1 mRNA CTD PMID:17018868 PMID:21628964 mercury atom affects abundance ISO RGD:737231 6480464 MT1A gene SNP affects the abundance of Mercury CTD PMID:22233731 mercury atom multiple interactions EXP   6480464 [MT1 co-treated with MT2] affects the susceptibility to Mercury CTD PMID:22008530 mercury atom increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A mRNA CTD PMID:12167210 PMID:12730625 mercury atom increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A protein CTD PMID:12491035 mercury atom increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A CTD PMID:15138662 mercury atom increases response to substance EXP   6480464 MT1 gene mutant form results in increased susceptibility to Mercury CTD PMID:15782327 mercury atom increases expression EXP   6480464 Mercury results in increased expression of MT1 protein CTD PMID:15138662 mercury atom increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1 mRNA; more ... CTD PMID:17018868 mercury atom increases expression EXP   6480464 Mercury results in increased expression of MT1 mRNA CTD PMID:17018868 mercury dichloride affects binding EXP   6480464 [Zinc binds to MT1 protein] which binds to Mercuric Chloride CTD PMID:15606775 mercury dichloride increases expression EXP   6480464 Mercuric Chloride results in increased expression of MT1 mRNA CTD PMID:19088408 more ... mercury dichloride increases expression ISO RGD:3117 6480464 Mercuric Chloride results in increased expression of MT1A mRNA CTD PMID:19720107 more ... mercury dichloride increases expression ISO RGD:3117 6480464 Mercuric Chloride results in increased expression of MT1A mRNA CTD PMID:20229497 more ... mercury dichloride affects expression ISO RGD:3117 6480464 Mercuric Chloride affects the expression of MT1A mRNA CTD PMID:10991963 mercury dichloride multiple interactions ISO RGD:3117 6480464 Vitamin E promotes the reaction [Mercuric Chloride results in increased expression of MT1A mRNA] CTD PMID:21787585 mercury dichloride increases expression ISO RGD:3117 6480464 Mercuric Chloride results in increased expression of MT1 mRNA; more ... CTD PMID:12815612 mercury dichloride increases expression EXP   6480464 Mercuric Chloride results in increased expression of MT1 mRNA CTD PMID:21094152 more ... mercury dichloride multiple interactions EXP   6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form co-treated with Mercuric Chloride] results in decreased abundance of Dopamine; more ... CTD PMID:18226494 mercury dichloride multiple interactions ISO RGD:3117 6480464 Curcumin affects the reaction [Mercuric Chloride results in increased expression of MT1A mRNA] CTD PMID:20229497 mercury dichloride increases expression ISO RGD:3117 6480464 Mercuric Chloride results in increased expression of MT1A mRNA CTD PMID:19720107 PMID:20229497 mercury dichloride increases expression EXP   6480464 Mercuric Chloride results in increased expression of MT1 mRNA CTD PMID:21094152 mercury(0) affects binding EXP   6480464 Mercury binds to MT1 protein CTD PMID:15603537 mercury(0) affects abundance ISO RGD:737231 6480464 MT1A gene polymorphism affects the abundance of Mercury CTD PMID:19515364 mercury(0) increases expression EXP   6480464 Mercury results in increased expression of MT1 mRNA CTD PMID:17018868 PMID:21628964 mercury(0) multiple interactions EXP   6480464 [MT1 co-treated with MT2] affects the susceptibility to Mercury CTD PMID:22008530 mercury(0) increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A mRNA CTD PMID:12167210 PMID:12730625 mercury(0) affects abundance ISO RGD:737231 6480464 MT1A gene SNP affects the abundance of Mercury CTD PMID:22233731 mercury(0) increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A protein CTD PMID:12491035 mercury(0) increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1A CTD PMID:15138662 mercury(0) increases response to substance EXP   6480464 MT1 gene mutant form results in increased susceptibility to Mercury CTD PMID:15782327 mercury(0) increases expression EXP   6480464 Mercury results in increased expression of MT1 protein CTD PMID:15138662 mercury(0) increases expression ISO RGD:3117 6480464 Mercury results in increased expression of MT1 mRNA; more ... CTD PMID:17018868 mercury(0) increases expression EXP   6480464 Mercury results in increased expression of MT1 mRNA CTD PMID:17018868 methapyrilene decreases expression ISO RGD:3117 6480464 Methapyrilene results in decreased expression of MT1A mRNA CTD PMID:15120968 methapyrilene increases expression ISO RGD:3117 6480464 Methapyrilene results in increased expression of MT1A mRNA CTD PMID:15890375 methotrexate increases expression ISO RGD:3117 6480464 Methotrexate results in increased expression of MT1A mRNA CTD PMID:15120968 methyl methanesulfonate affects expression ISO RGD:3117 6480464 Methyl Methanesulfonate affects the expression of MT1A mRNA CTD PMID:12974610 methylmercury chloride increases expression EXP   6480464 methylmercuric chloride results in increased expression of MT1 mRNA CTD PMID:21628964 microcystin-LR decreases expression EXP   6480464 cyanoginosin LR results in decreased expression of MT1 mRNA CTD PMID:17383702 microcystin-LR increases expression EXP   6480464 cyanoginosin LR results in increased expression of MT1 mRNA CTD PMID:17654400 mono(2-ethylhexyl) phthalate affects expression EXP   6480464 mono-(2-ethylhexyl)phthalate affects the expression of MT1 mRNA CTD PMID:21195148 N-acetyl-L-cysteine multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] affects the reaction [Acetylcysteine affects the susceptibility to Doxorubicin] CTD PMID:20600803 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions EXP   6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA; more ... CTD PMID:19840844 N-methyl-N-nitrosurea multiple interactions EXP   6480464 [Methylnitrosourea co-treated with Carrageenan] results in increased expression of MT1 protein CTD PMID:15928667 N-methyl-N-nitrosurea increases expression EXP   6480464 Methylnitrosourea results in increased expression of MT1 protein CTD PMID:15928667 N-nitrosodiethylamine increases response to substance EXP   6480464 MT1 gene mutant form results in increased susceptibility to Diethylnitrosamine CTD PMID:21159647 N-nitrosodiethylamine increases expression ISO RGD:3117 6480464 Diethylnitrosamine results in increased expression of MT1A mRNA CTD PMID:19041683 N-nitrosodimethylamine decreases expression ISO RGD:3117 6480464 Dimethylnitrosamine results in decreased expression of MT1A mRNA CTD PMID:14600272 PMID:17072980 N-nitrosodimethylamine decreases expression ISO RGD:3117 6480464 Dimethylnitrosamine results in decreased expression of MT1A mRNA CTD PMID:17072980 PMID:14600272 N-nitrosodimethylamine increases expression ISO RGD:3117 6480464 Dimethylnitrosamine results in increased expression of MT1A mRNA CTD PMID:15890375 nickel atom multiple interactions EXP   6480464 MT1 affects the reaction [Nickel affects the expression of CALR3 mRNA]; more ... CTD PMID:16166738 nickel atom increases expression EXP   6480464 Nickel results in increased expression of MT1 mRNA CTD PMID:12540486 nickel atom decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Nickel CTD PMID:16166738 nickel atom increases response to substance EXP   6480464 MT1 gene mutant form results in increased susceptibility to Nickel CTD PMID:16166738 nickel dichloride affects expression ISO RGD:3117 6480464 nickel chloride affects the expression of MT1A mRNA CTD PMID:22110744 nickel dichloride increases expression EXP   6480464 nickel chloride results in increased expression of MT1 mRNA CTD PMID:12729255 nickel sulfate affects expression EXP   6480464 nickel sulfate affects the expression of MT1 mRNA CTD PMID:12718980 nickel sulfate increases expression ISO RGD:3117 6480464 nickel sulfate results in increased expression of MT1A mRNA CTD PMID:19679144 nitric oxide multiple interactions EXP   6480464 Nitric Oxide affects the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] results in increased expression of MT1 mRNA] CTD PMID:14617770 nitric oxide multiple interactions ISO RGD:737231 6480464 Nitric Oxide binds to and results in decreased activity of MT1A protein CTD PMID:10548558 nitroprusside increases expression ISO RGD:737231 6480464 Nitroprusside results in increased expression of MT1A mRNA CTD PMID:17018880 nitroprusside multiple interactions ISO RGD:737231 6480464 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [Nitroprusside results in increased expression of MT1A mRNA]; more ... CTD PMID:17018880 ochratoxin A multiple interactions ISO RGD:737231 6480464 [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc co-treated with ochratoxin A] results in increased expression of MT1A mRNA CTD PMID:19720134 okadaic acid multiple interactions EXP   6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of MT1 mRNA CTD PMID:19840844 oleanolic acid increases expression ISO RGD:3117 6480464 Oleanolic Acid results in increased expression of MT1 mRNA CTD PMID:18706400 oleanolic acid increases expression EXP   6480464 Oleanolic Acid results in increased expression of MT1 mRNA CTD PMID:17637929 PMID:18706400 oleanolic acid increases expression ISO RGD:3117 6480464 Oleanolic Acid results in increased expression of MT1A mRNA; more ... CTD PMID:17637929 oleanolic acid increases expression EXP   6480464 Oleanolic Acid results in increased expression of MT1 mRNA CTD PMID:18706400 PMID:17637929 ozone multiple interactions EXP   6480464 anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [Ozone results in increased expression of MT1 mRNA] CTD PMID:17460151 ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:16183385 more ... ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:9700096 more ... ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:17095637 more ... ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:20123758 more ... ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:20123758 more ... ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 protein CTD PMID:16183385 PMID:18929643 ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:17460151 more ... ozone multiple interactions EXP   6480464 [Acetaminophen co-treated with Ozone] results in increased expression of MT1 mRNA; more ... CTD PMID:20123758 ozone increases expression ISO RGD:3117 6480464 Ozone results in increased expression of MT1A mRNA CTD PMID:16716893 ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 mRNA CTD PMID:16183385 more ... ozone multiple interactions EXP   6480464 SCGB1A1 protein affects the reaction [Ozone results in increased expression of MT1 mRNA] CTD PMID:9700096 ozone increases expression EXP   6480464 Ozone results in increased expression of MT1 protein CTD PMID:18929643 PMID:16183385 ozone multiple interactions EXP   6480464 MT1 protein affects the reaction [Ozone affects the expression of HMOX1 protein]; more ... CTD PMID:18929643 ozone affects response to substance EXP   6480464 MT1 protein affects the susceptibility to Ozone CTD PMID:18929643 ozone multiple interactions EXP   6480464 GCLM gene mutant form promotes the reaction [Ozone results in increased expression of MT1 mRNA] CTD PMID:20417186 paracetamol multiple interactions EXP   6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of MT1 mRNA; more ... CTD PMID:17585979 paracetamol increases expression ISO RGD:3117 6480464 Acetaminophen results in increased expression of MT1A mRNA CTD PMID:15120968 PMID:17202762 paracetamol affects expression ISO RGD:3117 6480464 Acetaminophen affects the expression of MT1A mRNA CTD PMID:16701773 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of MT1 mRNA CTD PMID:15606129 PMID:20123758 paracetamol multiple interactions EXP   6480464 Ozone promotes the reaction [Acetaminophen results in increased expression of MT1 mRNA]; more ... CTD PMID:20123758 paracetamol affects expression EXP   6480464 Acetaminophen affects the expression of MT1 mRNA CTD PMID:17562736 paracetamol increases expression EXP   6480464 Acetaminophen results in increased expression of MT1 mRNA CTD PMID:20123758 PMID:15606129 paracetamol increases expression ISO RGD:3117 6480464 Acetaminophen results in increased expression of MT1A mRNA CTD PMID:17202762 PMID:15120968 paraquat increases expression ISO RGD:3117 6480464 Paraquat results in increased expression of MT1A mRNA; more ... CTD PMID:16555045 paraquat multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] results in decreased expression of MT1 mRNA CTD PMID:18386188 paraquat increases expression ISO RGD:3117 6480464 Paraquat results in increased expression of MT1A mRNA CTD PMID:16555045 PMID:20553223 paraquat multiple interactions ISO RGD:3117 6480464 Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; more ... CTD PMID:20553223 paraquat increases expression EXP   6480464 Paraquat results in increased expression of MT1 mRNA CTD PMID:12595580 PMID:17215068 paraquat increases expression EXP   6480464 Paraquat results in increased expression of MT1 mRNA CTD PMID:17215068 PMID:12595580 paraquat decreases response to substance ISO RGD:3117 6480464 MT1A protein results in decreased susceptibility to Paraquat CTD PMID:15288509 parathion multiple interactions ISO RGD:737231 6480464 [Parathion co-treated with Estradiol] results in decreased expression of MT1A mRNA CTD PMID:17982697 pentetic acid decreases expression ISO RGD:3117 6480464 Pentetic Acid results in decreased expression of MT1A mRNA CTD PMID:21636019 phenacetin increases expression ISO RGD:3117 6480464 Phenacetin results in increased expression of MT1A mRNA CTD PMID:17082564 phenobarbital multiple interactions EXP   6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MT1 mRNA] CTD PMID:19482888 phenobarbital affects expression EXP   6480464 Phenobarbital affects the expression of MT1 mRNA CTD PMID:23091169 phenobarbital increases expression EXP   6480464 Phenobarbital results in increased expression of MT1 mRNA CTD PMID:19363144 PMID:19482888 phenobarbital decreases expression ISO RGD:3117 6480464 Phenobarbital results in decreased expression of MT1A mRNA CTD PMID:19162173 phenobarbital decreases expression EXP   6480464 Phenobarbital results in decreased expression of MT1 mRNA CTD PMID:19270015 phenobarbital increases expression EXP   6480464 Phenobarbital results in increased expression of MT1 mRNA CTD PMID:19482888 PMID:19363144 phenylhydrazine increases expression ISO RGD:3117 6480464 phenylhydrazine results in increased expression of MT1A mRNA CTD PMID:17082564 phorbol 13-acetate 12-myristate multiple interactions EXP   6480464 [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of MT1 mRNA CTD PMID:19840844 phorbol 13-acetate 12-myristate increases response to substance EXP   6480464 MT1 results in increased susceptibility to Tetradecanoylphorbol Acetate CTD PMID:9506445 phorone decreases expression ISO RGD:3117 6480464 phorone results in decreased expression of MT1A mRNA CTD PMID:7626009 phosgene affects expression EXP   6480464 Phosgene affects the expression of MT1 mRNA CTD PMID:16300373 piperonyl butoxide increases expression ISO RGD:3117 6480464 Piperonyl Butoxide results in increased expression of MT1A mRNA CTD PMID:15890375 pirinixic acid affects expression EXP   6480464 pirinixic acid affects the expression of MT1 mRNA CTD PMID:11798191 pirinixic acid decreases expression ISO RGD:3117 6480464 pirinixic acid results in decreased expression of MT1A mRNA CTD PMID:15890375 more ... pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of MT1 mRNA CTD PMID:20813756 more ... pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of MT1 mRNA CTD PMID:18301758 more ... pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of MT1 mRNA CTD PMID:17426115 more ... pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of MT1 mRNA CTD PMID:16221962 more ... pirinixic acid decreases expression ISO RGD:3117 6480464 pirinixic acid results in decreased expression of MT1A mRNA CTD PMID:15890375 PMID:19162173 pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of MT1 mRNA CTD PMID:18301758 more ... pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of MT1 mRNA CTD PMID:17321000 more ... pirinixic acid decreases expression ISO RGD:3117 6480464 pirinixic acid results in decreased expression of MT1A mRNA CTD PMID:19162173 PMID:15890375 pirinixic acid increases expression EXP   6480464 pirinixic acid results in increased expression of MT1 mRNA CTD PMID:17426115 more ... pirinixic acid multiple interactions EXP   6480464 PPARA protein affects the reaction [pirinixic acid results in decreased expression of MT1 mRNA] CTD PMID:17321000 pirinixic acid decreases expression EXP   6480464 pirinixic acid results in decreased expression of MT1 mRNA CTD PMID:20813756 more ... pirinixic acid multiple interactions EXP   6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MT1 mRNA CTD PMID:19710929 potassium chloride multiple interactions ISO RGD:3117 6480464 [Aldosterone co-treated with Sodium Chloride co-treated with Potassium Chloride] results in increased expression of MT1A protein; more ... CTD PMID:17616752 potassium dichromate increases expression EXP   6480464 Potassium Dichromate results in increased expression of MT1 mRNA CTD PMID:19276070 potassium dichromate increases expression ISO RGD:3117 6480464 Potassium Dichromate results in increased expression of MT1A mRNA CTD PMID:19167472 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:3117 6480464 Pregnenolone Carbonitrile results in decreased expression of MT1A mRNA CTD PMID:19162173 progesterone increases expression ISO RGD:737231 6480464 Progesterone results in increased expression of MT1A mRNA CTD PMID:18037150 progesterone affects expression EXP   6480464 Progesterone affects the expression of MT1 mRNA CTD PMID:17251523 quercetin multiple interactions ISO RGD:3117 6480464 Quercetin promotes the reaction [Cadmium results in increased expression of MT1 mRNA] CTD PMID:16226777 quercetin affects expression ISO RGD:3117 6480464 Quercetin affects the expression of MT1A mRNA CTD PMID:18178720 riddelliine increases expression ISO RGD:3117 6480464 riddelliine results in increased expression of MT1A mRNA CTD PMID:18047727 Ro 31-8220 multiple interactions EXP   6480464 Ro 31-8220 inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 Ro 31-8220 decreases expression EXP   6480464 Ro 31-8220 results in decreased expression of MT1 mRNA CTD PMID:11551972 rosiglitazone multiple interactions EXP   6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of MT1 mRNA CTD PMID:16054899 rosiglitazone increases expression ISO RGD:3117 6480464 rosiglitazone results in increased expression of MT1A mRNA CTD PMID:21515302 rotenone multiple interactions ISO RGD:3117 6480464 GPX4 protein inhibits the reaction [Rotenone results in increased expression of MT1 mRNA] CTD PMID:19818760 rotenone increases expression ISO RGD:3117 6480464 Rotenone results in increased expression of MT1 mRNA CTD PMID:19818760 S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO RGD:3117 6480464 Buthionine Sulfoximine results in increased expression of MT1A mRNA CTD PMID:7626009 S-butyl-DL-homocysteine (S,R)-sulfoximine increases activity EXP   6480464 Buthionine Sulfoximine results in increased activity of MT1 promoter CTD PMID:14576086 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions EXP   6480464 Buthionine Sulfoximine promotes the reaction [Copper results in increased activity of MT1 promoter] CTD PMID:14576086 salicylic acid increases expression ISO RGD:737231 6480464 Salicylic Acid results in increased expression of MT1A mRNA CTD PMID:20491607 serotonin multiple interactions EXP   6480464 [MT1 gene mutant form co-treated with MT2 gene mutant form] results in increased abundance of Serotonin CTD PMID:18226494 silicon dioxide increases expression EXP   6480464 Silicon Dioxide results in increased expression of MT1 mRNA CTD PMID:19073995 silver atom increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22079246 silver atom increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22036727 PMID:22546375 silver atom increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22036727 silver(0) increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22079246 silver(0) increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22036727 PMID:22546375 silver(0) increases expression ISO RGD:737231 6480464 Silver results in increased expression of MT1A mRNA CTD PMID:22036727 silver(1+) nitrate multiple interactions ISO RGD:737231 6480464 MTF1 mutant form inhibits the reaction [Silver Nitrate results in increased expression of MT1A mRNA] CTD PMID:19733233 silver(1+) nitrate increases expression ISO RGD:737231 6480464 Silver Nitrate results in increased expression of MT1A mRNA CTD PMID:19733233 more ... silver(1+) nitrate increases expression ISO RGD:737231 6480464 Silver Nitrate analog results in increased expression of MT1A mRNA CTD PMID:22831968 silver(1+) nitrate increases expression ISO RGD:737231 6480464 Silver Nitrate results in increased expression of MT1A mRNA CTD PMID:19733233 PMID:22831968 silver(1+) nitrate increases expression ISO RGD:737231 6480464 Silver Nitrate results in increased expression of MT1A mRNA CTD PMID:19733233 simvastatin increases expression ISO RGD:3117 6480464 Simvastatin results in increased expression of MT1A mRNA CTD PMID:19001041 sodium chloride multiple interactions ISO RGD:3117 6480464 Spironolactone inhibits the reaction [[Aldosterone co-treated with Sodium Chloride co-treated with Potassium Chloride] results in increased expression of MT1A protein] CTD PMID:17616752 sodium dichromate affects expression ISO RGD:3117 6480464 sodium bichromate affects the expression of MT1A mRNA CTD PMID:22110744 sodium dichromate increases expression EXP   6480464 sodium bichromate results in increased expression of MT1 mRNA CTD PMID:22155349 sodium dodecyl sulfate increases expression ISO RGD:737231 6480464 Sodium Dodecyl Sulfate results in increased expression of MT1A mRNA CTD PMID:20491607 spironolactone multiple interactions ISO RGD:3117 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of MT1A mRNA] CTD PMID:19333130 spironolactone multiple interactions ISO RGD:3117 6480464 Spironolactone inhibits the reaction [[Aldosterone co-treated with Sodium Chloride co-treated with Potassium Chloride] results in increased expression of MT1A protein] CTD PMID:17616752 staurosporine multiple interactions EXP   6480464 Staurosporine inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:15142038 streptozocin increases expression ISO RGD:3117 6480464 Streptozocin results in increased expression of MT1A mRNA CTD PMID:16684804 streptozocin multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA] CTD PMID:19369054 streptozocin increases expression ISO RGD:3117 6480464 Streptozocin results in increased expression of MT1A mRNA CTD PMID:16684804 PMID:19369054 streptozocin multiple interactions ISO RGD:3117 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA] CTD PMID:16684804 succimer multiple interactions EXP   6480464 [Succimer binds to Magnetite Nanoparticles] which results in decreased expression of MT1 mRNA CTD PMID:21641980 sulforaphane increases expression ISO RGD:737231 6480464 sulforafan results in increased expression of MT1A mRNA; more ... CTD PMID:16033772 tamibarotene increases expression ISO RGD:737231 6480464 Am 80 results in increased expression of MT1A mRNA; more ... CTD PMID:15498508 tamoxifen affects expression EXP   6480464 Tamoxifen affects the expression of MT1 mRNA CTD PMID:17555576 PMID:20937368 tamoxifen affects expression EXP   6480464 Tamoxifen affects the expression of MT1 mRNA CTD PMID:20937368 PMID:17555576 tamoxifen multiple interactions EXP   6480464 Tamoxifen inhibits the reaction [bisphenol A inhibits the reaction [Cadmium results in increased expression of MT1 protein]] CTD PMID:11771854 tert-butyl hydroperoxide decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to tert-Butylhydroperoxide CTD PMID:16150881 testosterone multiple interactions ISO RGD:3117 6480464 Testosterone inhibits the reaction [Dexamethasone results in increased expression of MT1A mRNA] CTD PMID:20032058 tetrachloromethane decreases expression ISO RGD:3117 6480464 Carbon Tetrachloride results in decreased expression of MT1A mRNA CTD PMID:16239168 tetrachloromethane increases expression EXP   6480464 Carbon Tetrachloride results in increased expression of MT1 protein CTD PMID:20371262 thapsigargin increases expression EXP   6480464 Thapsigargin results in increased expression of MT1 mRNA CTD PMID:15019097 thapsigargin increases expression ISO RGD:737231 6480464 Thapsigargin results in increased expression of MT1A mRNA CTD PMID:21694771 thimerosal increases expression EXP   6480464 Thimerosal results in increased expression of MT1 mRNA; more ... CTD PMID:19357975 thimerosal affects expression EXP   6480464 Thimerosal affects the expression of MT1 mRNA CTD PMID:19386279 thioacetamide affects response to substance EXP   6480464 MT1 protein affects the susceptibility to Thioacetamide CTD PMID:15979673 thioacetamide increases expression EXP   6480464 Thioacetamide results in increased expression of MT1 protein CTD PMID:15979673 toluene decreases expression ISO RGD:3117 6480464 Toluene results in decreased expression of MT1A mRNA CTD PMID:22166486 toluene increases expression ISO RGD:3117 6480464 Toluene results in increased expression of MT1A mRNA CTD PMID:22166486 trichloroethene decreases expression ISO RGD:3117 6480464 Trichloroethylene results in decreased expression of MT1A mRNA CTD PMID:19448997 trichostatin A multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [trichostatin A promotes the reaction [Zinc results in increased expression of MT1 mRNA]] CTD PMID:21467744 troglitazone increases expression ISO RGD:3117 6480464 troglitazone results in increased expression of MT1A mRNA CTD PMID:21515302 tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of MT1 mRNA CTD PMID:17127020 PMID:15019097 tunicamycin increases expression EXP   6480464 Tunicamycin results in increased expression of MT1 mRNA CTD PMID:15019097 PMID:17127020 undecane increases expression ISO RGD:3117 6480464 undecane results in increased expression of MT1A protein CTD PMID:17337753 valproic acid increases expression EXP   6480464 Valproic Acid results in increased expression of MT1 mRNA CTD PMID:15345369 vanadium atom multiple interactions ISO RGD:3117 6480464 Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein] CTD PMID:15565650 vanadium(0) multiple interactions ISO RGD:3117 6480464 Vanadium inhibits the reaction [2-Acetylaminofluorene results in increased expression of MT1A protein] CTD PMID:15565650 vanadyl sulfate multiple interactions ISO RGD:3117 6480464 vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA] CTD PMID:16684804 vanadyl sulfate increases expression ISO RGD:3117 6480464 vanadyl sulfate results in increased expression of MT1A mRNA CTD PMID:19679144 vancomycin decreases expression EXP   6480464 Vancomycin results in decreased expression of MT1 mRNA CTD PMID:18930951 vancomycin increases expression ISO RGD:3117 6480464 Vancomycin results in increased expression of MT1A mRNA CTD PMID:18289764 wortmannin multiple interactions EXP   6480464 wortmannin inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 zinc atom affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:10548558 zinc atom multiple interactions ISO RGD:3117 6480464 Zinc Sulfate inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA] CTD PMID:3609024 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:11311571 more ... zinc atom multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA] CTD PMID:19369054 zinc atom decreases expression ISO RGD:3117 6480464 Zinc deficiency results in decreased expression of MT1A mRNA CTD PMID:11717422 more ... zinc atom multiple interactions ISO RGD:3117 6480464 Zinc deficiency inhibits the reaction [IL1A protein results in increased expression of MT1A mRNA] CTD PMID:12514266 zinc atom multiple interactions EXP   6480464 MT1 protein affects the reaction [Zinc results in increased expression of CSF1 mRNA] CTD PMID:12112025 zinc atom multiple interactions EXP   6480464 EP300 protein affects the reaction [Zinc results in increased expression of MT1 mRNA]; more ... CTD PMID:18458062 zinc atom multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA] CTD PMID:18605988 PMID:21467744 zinc atom multiple interactions ISO RGD:3117 6480464 [Butyrates co-treated with Zinc] results in increased expression of MT1A mRNA; more ... CTD PMID:1597404 zinc atom multiple interactions ISO RGD:3117 6480464 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene promotes the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:11311571 zinc atom multiple interactions ISO RGD:3117 6480464 SLC30A1 protein promotes the reaction [[MT1 protein co-treated with MT2 protein] inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]] CTD PMID:15041749 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc atom multiple interactions EXP   6480464 Zinc promotes the reaction [MTF1 protein binds to MT1 promoter] CTD PMID:18605988 PMID:21035574 zinc atom decreases expression EXP   6480464 Zinc deficiency results in decreased expression of MT1 mRNA CTD PMID:12514265 PMID:12801924 zinc atom multiple interactions EXP   6480464 Zinc deficiency inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 zinc atom multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] promotes the reaction [SLC30A1 protein inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]]; more ... CTD PMID:15041749 zinc atom multiple interactions EXP   6480464 MT1 gene mutant form inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] affects the localization of Zinc] CTD PMID:14617770 zinc atom increases expression ISO RGD:3117 6480464 Zinc deficiency results in increased expression of MT1A mRNA; more ... CTD PMID:16140947 zinc atom decreases expression ISO RGD:3117 6480464 Zinc deficiency results in decreased expression of MT1A mRNA CTD PMID:11717422 more ... zinc atom multiple interactions ISO RGD:3117 6480464 Zinc affects the reaction [Zinc deficiency results in increased expression of MT1A mRNA]; more ... CTD PMID:16140947 zinc atom multiple interactions ISO RGD:3117 6480464 IL1A protein inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA] CTD PMID:9278552 PMID:9649590 zinc atom multiple interactions ISO RGD:737231 6480464 MT1A gene polymorphism affects the reaction [Zinc results in decreased expression of CCL2 protein]; more ... CTD PMID:18215484 zinc atom multiple interactions ISO RGD:737231 6480464 MT1A gene polymorphism affects the reaction [Zinc results in decreased expression of IL1B mRNA]; more ... CTD PMID:18316168 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc atom decreases expression EXP   6480464 Zinc deficiency results in decreased expression of MT1 mRNA; more ... CTD PMID:12514265 zinc atom decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Zinc deficiency CTD PMID:12514265 zinc atom increases abundance EXP   6480464 MT1 protein results in increased abundance of Zinc CTD PMID:12514265 zinc atom multiple interactions EXP   6480464 [Zinc promotes the reaction [MTF1 protein binds to EP300 protein]] which results in increased expression of MT1 mRNA; more ... CTD PMID:21035574 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc atom multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [trichostatin A promotes the reaction [Zinc results in increased expression of MT1 mRNA]]; more ... CTD PMID:21467744 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc atom multiple interactions ISO RGD:737231 6480464 tris(1,10-phenanthroline)chromium(III) chloride inhibits the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:20043934 zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:11168427 more ... zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 PMID:11163336 zinc atom affects binding EXP   6480464 MT1 protein binds to Zinc CTD PMID:22001350 zinc atom multiple interactions EXP   6480464 Dithiothreitol results in increased reduction of [MT1 protein binds to Zinc]; more ... CTD PMID:22001350 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:12716893 more ... zinc atom affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:20329713 PMID:10548558 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:11163336 PMID:10605938 zinc atom multiple interactions EXP   6480464 [Zinc binds to MTF1 protein] affects the reaction [MTF1 protein binds to MT1 promoter] CTD PMID:10734081 zinc atom multiple interactions EXP   6480464 cerous chloride promotes the reaction [Zinc binds to MT1 protein] CTD PMID:16204935 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17241390 more ... zinc atom multiple interactions ISO RGD:3117 6480464 Zinc inhibits the reaction [Cadmium Chloride results in increased expression of MT1A mRNA] CTD PMID:20096345 zinc atom multiple interactions ISO RGD:3117 6480464 [Folic Acid co-treated with Zinc] inhibits the reaction [Homocysteine results in decreased expression of MT1A mRNA]; more ... CTD PMID:19641857 zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17363595 more ... zinc atom affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:10548558 PMID:20329713 zinc atom affects binding ISO RGD:737231 6480464 MT1A protein binds to Zinc CTD PMID:22242602 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:18172885 more ... zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc atom multiple interactions ISO RGD:737231 6480464 [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT1A mRNA; more ... CTD PMID:19720134 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:18172885 more ... zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17074742 more ... zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:12716893 more ... zinc atom multiple interactions ISO RGD:737231 6480464 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate promotes the reaction [Zinc results in increased expression of MT1A mRNA]; more ... CTD PMID:17363595 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:17018881 zinc atom affects expression ISO RGD:3117 6480464 Zinc affects the expression of MT1 mRNA CTD PMID:15867272 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 protein CTD PMID:16987576 zinc atom increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:11163336 zinc atom affects binding EXP   6480464 [Zinc binds to MT1 protein] which binds to Mercuric Chloride; more ... CTD PMID:15606775 zinc atom affects binding EXP   6480464 Zinc binds to MT1 protein CTD PMID:16987576 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc atom multiple interactions ISO RGD:3117 6480464 [Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A protein; more ... CTD PMID:17241390 zinc atom multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Daunorubicin results in increased expression of MT1A mRNA]; more ... CTD PMID:12204545 zinc atom affects expression ISO RGD:3117 6480464 Zinc affects the expression of MT1A mRNA CTD PMID:14690761 zinc atom increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15612480 zinc atom increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc atom multiple interactions ISO RGD:737231 6480464 [Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNA CTD PMID:15867382 zinc atom multiple interactions ISO RGD:737231 6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:12716893 zinc dichloride affects binding EXP   6480464 zinc chloride binds to MT1 protein CTD PMID:16987576 zinc dichloride multiple interactions ISO RGD:3117 6480464 zinc chloride promotes the reaction [Glucose results in increased expression of MT1A mRNA] CTD PMID:23056475 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 mRNA CTD PMID:11551972 more ... zinc dichloride multiple interactions EXP   6480464 Edetic Acid inhibits the reaction [zinc chloride promotes the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA]] CTD PMID:14998373 zinc dichloride increases expression ISO RGD:3117 6480464 zinc chloride results in increased expression of MT1A mRNA; more ... CTD PMID:17637929 PMID:8928928 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 mRNA CTD PMID:11551972 more ... zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 mRNA CTD PMID:11551972 more ... zinc dichloride affects response to substance EXP   6480464 MT1 affects the susceptibility to zinc chloride CTD PMID:19835899 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 mRNA CTD PMID:17637929 PMID:11551972 zinc dichloride multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA]; more ... CTD PMID:11551972 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 protein CTD PMID:15288509 PMID:16987576 zinc dichloride decreases expression EXP   6480464 zinc chloride results in decreased expression of MT1 protein CTD PMID:17910954 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 protein CTD PMID:16987576 PMID:15288509 zinc dichloride increases expression ISO RGD:3117 6480464 zinc chloride results in increased expression of MT1A mRNA; more ... CTD PMID:17637929 zinc dichloride decreases response to substance ISO RGD:3117 6480464 MT1A protein results in decreased susceptibility to zinc chloride CTD PMID:15288509 zinc dichloride increases expression EXP   6480464 zinc chloride results in increased expression of MT1 mRNA CTD PMID:17637929 zinc sulfate multiple interactions ISO RGD:737231 6480464 Zinc Sulfate promotes the reaction [Nitroprusside results in increased expression of MT1A mRNA] CTD PMID:17018880 zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:11208937 more ... zinc sulfate multiple interactions ISO RGD:3117 6480464 Zinc Sulfate inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA] CTD PMID:3609024 zinc sulfate multiple interactions ISO RGD:3117 6480464 [Zinc Sulfate co-treated with EGF protein] results in increased expression of MT1A mRNA CTD PMID:7705776 zinc sulfate multiple interactions ISO RGD:3117 6480464 [Zinc Sulfate co-treated with Cadmium Chloride] results in increased expression of MT1A mRNA CTD PMID:2219126 zinc sulfate multiple interactions EXP   6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Zinc Sulfate results in increased expression of MT1 mRNA]; more ... CTD PMID:15142038 zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:11208937 more ... zinc sulfate decreases expression ISO RGD:3117 6480464 Zinc Sulfate deficiency results in decreased expression of MT1A mRNA CTD PMID:11208937 zinc sulfate increases expression ISO RGD:737231 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:17018880 PMID:19083439 zinc sulfate increases expression EXP   6480464 Zinc Sulfate results in increased expression of MT1 mRNA CTD PMID:10952993 PMID:15142038 zinc sulfate multiple interactions ISO RGD:3117 6480464 Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; more ... CTD PMID:20553223 zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:15884113 more ... zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:15884113 more ... zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:15884113 more ... zinc sulfate decreases expression EXP   6480464 Zinc Sulfate deficiency results in decreased expression of MT1 mRNA CTD PMID:10952993 zinc sulfate increases expression EXP   6480464 Zinc Sulfate results in increased expression of MT1 mRNA CTD PMID:10952993 zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:17241390 more ... zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:15884113 more ... zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:17074742 more ... zinc sulfate increases expression ISO RGD:3117 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:17074742 more ... zinc sulfate multiple interactions ISO RGD:3117 6480464 [Zinc Sulfate co-treated with ferrous sulfate] results in increased expression of and affects the localization of MT1A protein; more ... CTD PMID:17241390 zinc sulfate increases expression ISO RGD:737231 6480464 Zinc Sulfate results in increased expression of MT1A mRNA CTD PMID:17018880 zinc sulfate multiple interactions EXP   6480464 [Ethanol co-treated with Zinc Sulfate] results in increased expression of MT1 protein CTD PMID:15920153 zinc(0) affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:10548558 zinc(0) multiple interactions ISO RGD:737231 6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:12716893 zinc(0) multiple interactions ISO RGD:737231 6480464 [Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNA CTD PMID:15867382 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15612480 zinc(0) affects expression ISO RGD:3117 6480464 Zinc affects the expression of MT1A mRNA CTD PMID:14690761 zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Daunorubicin results in increased expression of MT1A mRNA]; more ... CTD PMID:12204545 zinc(0) multiple interactions ISO RGD:3117 6480464 [Zinc co-treated with Iron] results in increased expression of and affects the localization of MT1A protein; more ... CTD PMID:17241390 zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc(0) affects binding EXP   6480464 Zinc binds to MT1 protein CTD PMID:16987576 zinc(0) affects binding EXP   6480464 [Zinc binds to MT1 protein] which binds to Mercuric Chloride; more ... CTD PMID:15606775 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:11163336 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 protein CTD PMID:16987576 zinc(0) affects expression ISO RGD:3117 6480464 Zinc affects the expression of MT1 mRNA CTD PMID:15867272 zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:17018881 zinc(0) multiple interactions ISO RGD:737231 6480464 1L-6-hydroxymethyl-chiro-inositol 2(R)-2-O-methyl-3-O-octadecylcarbonate promotes the reaction [Zinc results in increased expression of MT1A mRNA]; more ... CTD PMID:17363595 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:12716893 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17074742 more ... zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:18172885 more ... zinc(0) multiple interactions ISO RGD:737231 6480464 [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine co-treated with Zinc] results in increased expression of MT1A mRNA; more ... CTD PMID:19720134 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15867382 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:18172885 more ... zinc(0) affects binding ISO RGD:737231 6480464 MT1A protein binds to Zinc CTD PMID:22242602 zinc(0) affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:10548558 PMID:20329713 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17363595 more ... zinc(0) multiple interactions ISO RGD:3117 6480464 [Folic Acid co-treated with Zinc] inhibits the reaction [Homocysteine results in decreased expression of MT1A mRNA]; more ... CTD PMID:19641857 zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc inhibits the reaction [Cadmium Chloride results in increased expression of MT1A mRNA] CTD PMID:20096345 zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:17241390 more ... zinc(0) multiple interactions EXP   6480464 cerous chloride promotes the reaction [Zinc binds to MT1 protein] CTD PMID:16204935 zinc(0) multiple interactions EXP   6480464 [Zinc binds to MTF1 protein] affects the reaction [MTF1 protein binds to MT1 promoter] CTD PMID:10734081 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:11163336 PMID:10605938 zinc(0) affects binding ISO RGD:737231 6480464 Zinc binds to MT1A protein CTD PMID:20329713 PMID:10548558 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:12716893 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc(0) multiple interactions EXP   6480464 Dithiothreitol results in increased reduction of [MT1 protein binds to Zinc]; more ... CTD PMID:22001350 zinc(0) affects binding EXP   6480464 MT1 protein binds to Zinc CTD PMID:22001350 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 PMID:11163336 zinc(0) increases expression ISO RGD:737231 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:11168427 more ... zinc(0) multiple interactions ISO RGD:737231 6480464 tris(1,10-phenanthroline)chromium(III) chloride inhibits the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:20043934 zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:15952664 more ... zinc(0) multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [trichostatin A promotes the reaction [Zinc results in increased expression of MT1 mRNA]]; more ... CTD PMID:21467744 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc(0) multiple interactions EXP   6480464 [Zinc promotes the reaction [MTF1 protein binds to EP300 protein]] which results in increased expression of MT1 mRNA; more ... CTD PMID:21035574 zinc(0) increases abundance EXP   6480464 MT1 protein results in increased abundance of Zinc CTD PMID:12514265 zinc(0) decreases response to substance EXP   6480464 MT1 protein results in decreased susceptibility to Zinc deficiency CTD PMID:12514265 zinc(0) decreases expression EXP   6480464 Zinc deficiency results in decreased expression of MT1 mRNA; more ... CTD PMID:12514265 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc(0) multiple interactions ISO RGD:737231 6480464 MT1A gene polymorphism affects the reaction [Zinc results in decreased expression of IL1B mRNA]; more ... CTD PMID:18316168 zinc(0) multiple interactions ISO RGD:737231 6480464 MT1A gene polymorphism affects the reaction [Zinc results in decreased expression of CCL2 protein]; more ... CTD PMID:18215484 zinc(0) multiple interactions ISO RGD:3117 6480464 IL1A protein inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA] CTD PMID:9278552 PMID:9649590 zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc affects the reaction [Zinc deficiency results in increased expression of MT1A mRNA]; more ... CTD PMID:16140947 zinc(0) decreases expression ISO RGD:3117 6480464 Zinc deficiency results in decreased expression of MT1A mRNA CTD PMID:11717422 more ... zinc(0) increases expression ISO RGD:3117 6480464 Zinc deficiency results in increased expression of MT1A mRNA; more ... CTD PMID:16140947 zinc(0) multiple interactions EXP   6480464 MT1 gene mutant form inhibits the reaction [[IL1B protein co-treated with TNF protein co-treated with IFNG protein] affects the localization of Zinc] CTD PMID:14617770 zinc(0) multiple interactions EXP   6480464 [MT1 protein co-treated with MT2 protein] promotes the reaction [SLC30A1 protein inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]]; more ... CTD PMID:15041749 zinc(0) multiple interactions EXP   6480464 Zinc deficiency inhibits the reaction [2-tert-butylhydroquinone results in increased expression of MT1 mRNA] CTD PMID:14998373 zinc(0) decreases expression EXP   6480464 Zinc deficiency results in decreased expression of MT1 mRNA CTD PMID:12514265 PMID:12801924 zinc(0) multiple interactions EXP   6480464 Zinc promotes the reaction [MTF1 protein binds to MT1 promoter] CTD PMID:18605988 PMID:21035574 zinc(0) increases expression EXP   6480464 Zinc results in increased expression of MT1 mRNA CTD PMID:10605938 more ... zinc(0) multiple interactions ISO RGD:3117 6480464 SLC30A1 protein promotes the reaction [[MT1 protein co-treated with MT2 protein] inhibits the reaction [SLC30A1 gene mutant form results in increased susceptibility to Zinc]] CTD PMID:15041749 zinc(0) multiple interactions ISO RGD:3117 6480464 1-hydroxy-2-oxo-3,3-bis(2-aminoethyl)-1-triazene promotes the reaction [Zinc results in increased expression of MT1A mRNA] CTD PMID:11311571 zinc(0) multiple interactions EXP   6480464 chromium hexavalent ion inhibits the reaction [Zinc results in increased expression of MT1 mRNA] CTD PMID:18605988 PMID:21467744 zinc(0) multiple interactions EXP   6480464 EP300 protein affects the reaction [Zinc results in increased expression of MT1 mRNA]; more ... CTD PMID:18458062 zinc(0) multiple interactions EXP   6480464 MT1 protein affects the reaction [Zinc results in increased expression of CSF1 mRNA] CTD PMID:12112025 zinc(0) multiple interactions ISO RGD:3117 6480464 [Butyrates co-treated with Zinc] results in increased expression of MT1A mRNA; more ... CTD PMID:1597404 zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc deficiency inhibits the reaction [IL1A protein results in increased expression of MT1A mRNA] CTD PMID:12514266 zinc(0) decreases expression ISO RGD:3117 6480464 Zinc deficiency results in decreased expression of MT1A mRNA CTD PMID:11717422 more ... zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA] CTD PMID:19369054 zinc(0) increases expression ISO RGD:3117 6480464 Zinc results in increased expression of MT1A mRNA CTD PMID:11311571 more ... zinc(0) multiple interactions ISO RGD:3117 6480464 Zinc Sulfate inhibits the reaction [Zinc deficiency results in decreased expression of MT1A mRNA] CTD PMID:3609024 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) cellular metal ion homeostasis   IDA   2290270 MGI:MGI:2387885|PMID:12130647 MGI MGI:MGI:2387885 PMID:12130647 cellular metal ion homeostasis   IDA   2290270 MGI:MGI:3044518|PMID:15033980 MGI MGI:MGI:3044518 PMID:15033980 cellular response to chromate   IDA   2290270 MGI:MGI:3820854|PMID:18605988 MGI MGI:MGI:3820854 PMID:18605988 cellular response to zinc ion   IDA   2290270 MGI:MGI:3820854|PMID:18605988 MGI MGI:MGI:3820854 PMID:18605988 cellular zinc ion homeostasis   IMP MGI:MGI:2668454 2290270 MGI:MGI:2177111|PMID:11792622 MGI MGI:MGI:2177111 PMID:11792622 detoxification of copper ion   IGI MGI:MGI:97172|MGI:MGI:99400 2290270 MGI:MGI:80756|PMID:8640230 MGI MGI:MGI:80756 PMID:8640230 negative regulation of neuron apoptotic process   IDA   2290270 MGI:MGI:5315330|PMID:21359432 UniProtKB MGI:MGI:5315330 PMID:21359432 nitric oxide mediated signal transduction   IMP MGI:MGI:2668454 2290270 MGI:MGI:2177111|PMID:11792622 MGI MGI:MGI:2177111 PMID:11792622 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) cytosol   IDA   2290270 MGI:MGI:1098346|PMID:9358851 MGI MGI:MGI:1098346 PMID:9358851 intracellular   IMP MGI:MGI:2668454 2290270 MGI:MGI:2177111|PMID:11792622 GOC MGI:MGI:2177111 PMID:11792622 lysosome   IDA   2290270 MGI:MGI:1098346|PMID:9358851 MGI MGI:MGI:1098346 PMID:9358851 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) copper ion binding   IDA   2290270 MGI:MGI:1098346|PMID:9358851 MGI MGI:MGI:1098346 PMID:9358851 metal ion binding   IDA   2290270 MGI:MGI:2387885|PMID:12130647 MGI MGI:MGI:2387885 PMID:12130647 metal ion binding   IDA   2290270 MGI:MGI:3044518|PMID:15033980 MGI MGI:MGI:3044518 PMID:15033980 zinc ion binding   TAS   2290270 MGI:MGI:2177111|PMID:11792622 MGI MGI:MGI:2177111 PMID:11792622 Molecular Pathway Annotations External Database Links KEGG Pathway Mineral absorption Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) abnormal astrocyte morphology   IAGP   5509061   MGI PMID:10947810 abnormal circulating enzyme level   IAGP   5509061   MGI PMID:8290567 abnormal compact bone morphology   IAGP   5509061   MGI PMID:10869470 abnormal hepatocyte morphology   IAGP   5509061   MGI PMID:10087053 abnormal humoral immune response   IAGP   5509061   MGI PMID:10906280 abnormal intestinal mineral absorption   IAGP   5509061   MGI PMID:9566988 abnormal ion homeostasis   IAGP   5509061   MGI PMID:8367468 abnormal learning/memory/conditioning   IAGP   5509061   MGI PMID:16430929 abnormal lipid homeostasis   IAGP   5509061   MGI PMID:10087053 abnormal liver morphology   IAGP   5509061   MGI PMID:8290567 abnormal long bone epiphyseal ossification zone morphology   IAGP   5509061   MGI PMID:10869470 abnormal long bone epiphyseal plate morphology   IAGP   5509061   MGI PMID:10869470 abnormal lymphocyte physiology   IAGP   5509061   MGI PMID:10906280 abnormal microglial cell morphology   IAGP   5509061   MGI PMID:10087067 abnormal microglial cell morphology   IAGP   5509061   MGI PMID:10947810 abnormal microglial cell morphology   IAGP   5509061   MGI PMID:11585628 abnormal microglial cell physiology   IAGP   5509061   MGI PMID:10087067 abnormal pancreas morphology   IAGP   5509061   MGI PMID:8683339 abnormal physiological response to xenobiotic   IAGP   5509061   MGI PMID:10426817 abnormal physiological response to xenobiotic   IAGP   5509061   MGI PMID:10966523 abnormal renal glomerulus morphology   IAGP   5509061   MGI PMID:8683339 abnormal reproductive system physiology   IAGP   5509061   MGI PMID:10460198 abnormal retinal ganglion layer morphology   IAGP   5509061   MGI PMID:16936113 abnormal trabecular bone morphology   IAGP   5509061   MGI PMID:10869470 abnormal zinc homeostasis   IAGP   5509061   MGI PMID:8683339 abnormal zinc homeostasis   IAGP   5509061   MGI PMID:10460198 abnormal zinc homeostasis   IAGP   5509061   MGI PMID:10947810 astrocytosis   IAGP   5509061   MGI PMID:10087067 astrocytosis   IAGP   5509061   MGI PMID:11585628 clonic seizures   IAGP   5509061   MGI PMID:10947810 complete embryonic lethality   IAGP   5509061   MGI PMID:8640230 complete postnatal lethality   IAGP   5509061   MGI PMID:8640230 decreased B cell number   IAGP   5509061   MGI PMID:10906280 decreased body size   IAGP   5509061   MGI PMID:8640230 decreased bone mass   IAGP   5509061   MGI PMID:10869470 decreased bone mineral content   IAGP   5509061   MGI PMID:10869470 decreased compact bone thickness   IAGP   5509061   MGI PMID:10869470 decreased hepatocyte proliferation   IAGP   5509061   MGI PMID:15618127 decreased liver regeneration   IAGP   5509061   MGI PMID:15618127 decreased T cell number   IAGP   5509061   MGI PMID:10906280 dilated kidney collecting duct   IAGP   5509061   MGI PMID:10966523 dilated proximal convoluted tubules   IAGP   5509061   MGI PMID:10966523 enlarged kidney   IAGP   5509061   MGI PMID:10966523 enlarged liver   IAGP   5509061   MGI PMID:10966523 enlarged spleen   IAGP   5509061   MGI PMID:10906280 hemorrhage   IAGP   5509061   MGI PMID:10087067 hepatic necrosis   IAGP   5509061   MGI PMID:10087053 hepatic necrosis   IAGP   5509061   MGI PMID:8290567 impaired wound healing   IAGP   5509061   MGI PMID:10087067 increased apoptosis   IAGP   5509061   MGI PMID:10087067 increased blood urea nitrogen level   IAGP   5509061   MGI PMID:10966523 increased CD4-positive T cell number   IAGP   5509061   MGI PMID:10906280 increased CD8-positive T cell number   IAGP   5509061   MGI PMID:10906280 increased circulating alanine transaminase level   IAGP   5509061   MGI PMID:10087053 increased circulating alkaline phosphatase level   IAGP   5509061   MGI PMID:8290567 increased glomerular capsule space   IAGP   5509061   MGI PMID:8683339 increased IgG level   IAGP   5509061   MGI PMID:10906280 increased IgM level   IAGP   5509061   MGI PMID:10906280 increased incidence of chemically-induced tumors   IAGP   5509061   MGI PMID:10087053 increased incidence of chemically-induced tumors   IAGP   5509061   MGI PMID:10426817 increased interleukin-1 beta secretion   IAGP   5509061   MGI PMID:11585628 increased interleukin-6 secretion   IAGP   5509061   MGI PMID:11585628 increased lymphocyte cell number   IAGP   5509061   MGI PMID:10906280 increased macrophage cell number   IAGP   5509061   MGI PMID:10087067 increased neuron apoptosis   IAGP   5509061   MGI PMID:11585628 increased neuron apoptosis   IAGP   5509061   MGI PMID:10947810 increased neutrophil cell number   IAGP   5509061   MGI PMID:16166738 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:10087053 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:16936113 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:16166738 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:10966523 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:10947810 increased physiological sensitivity to xenobiotic   IAGP   5509061   MGI PMID:10869470 increased plasma cell number   IAGP   5509061   MGI PMID:10906280 increased renal tubule apoptosis   IAGP   5509061   MGI PMID:10966523 increased sensitivity to induced cell death   IAGP   5509061   MGI PMID:8640230 increased sensitivity to xenobiotic induced morbidity/mortality   IAGP   5509061   MGI PMID:10087053 increased sensitivity to xenobiotic induced morbidity/mortality   IAGP   5509061   MGI PMID:16166738 increased spleen weight   IAGP   5509061   MGI PMID:10906280 increased susceptibility to experimental autoimmune encephalomyelitis   IAGP   5509061   MGI PMID:11585628 increased susceptibility to injury   IAGP   5509061   MGI PMID:10764993 increased susceptibility to pharmacologically induced seizures   IAGP   5509061   MGI PMID:10947810 increased thymocyte apoptosis   IAGP   5509061   MGI PMID:10413187 increased tumor incidence   IAGP   5509061   MGI PMID:12807749 increased tumor necrosis factor secretion   IAGP   5509061   MGI PMID:11585628 increased urine glucose level   IAGP   5509061   MGI PMID:10966523 kidney atrophy   IAGP   5509061   MGI PMID:10966523 kidney degeneration   IAGP   5509061   MGI PMID:10966523 kidney inflammation   IAGP   5509061   MGI PMID:10966523 liver degeneration   IAGP   5509061   MGI PMID:8290567 lung inflammation   IAGP   5509061   MGI PMID:16166738 nephrocalcinosis   IAGP   5509061   MGI PMID:10966523 no abnormal phenotype detected   IAGP   5509061   MGI PMID:8640230 oxidative stress   IAGP   5509061   MGI PMID:11585628 partial embryonic lethality during organogenesis   IAGP   5509061   MGI PMID:8640230 premature death   IAGP   5509061   MGI PMID:8290567 renal interstitial fibrosis   IAGP   5509061   MGI PMID:10966523 renal necrosis   IAGP   5509061   MGI PMID:10966523 spleen hyperplasia   IAGP   5509061   MGI PMID:10906280 tonic-clonic seizures   IAGP   5509061   MGI PMID:10947810 weight loss   IAGP   5509061   MGI PMID:10869470 Disease Annotations Acute-Phase Reaction  (ISS) Amyotrophic Lateral Sclerosis  (IEP) Cerebral Hemorrhage  (ISS) Encephalomyelitis, Autoimmune, Experimental  (IEP) Hyperoxia  (IEP) Kidney Diseases  (ISS) Gene-Chemical Interaction Annotations (-)-selegiline  (EXP) (2,4,5-trichlorophenoxy)acetic acid  (EXP) (R)-lipoic acid  (EXP) 1,2,4-trimethylbenzene  (ISO) 1,4-benzoquinone  (EXP) 1,4-dithiothreitol  (EXP) 1-naphthyl isothiocyanate  (ISO) 17alpha-ethynylestradiol  (EXP,ISO) 17beta-estradiol  (ISO) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2,4-dinitrotoluene  (ISO) 2-acetamidofluorene  (ISO) 2-butoxyethanol  (EXP) 2-nitrofluorene  (ISO) 3,4-methylenedioxymethamphetamine  (EXP) 3-isobutyl-1-methyl-7H-xanthine  (EXP) 3H-1,2-dithiole-3-thione  (ISO) 4,4'-diaminodiphenylmethane  (EXP) 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (ISO) 4-hydroxynon-2-enal  (EXP) 5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (EXP) acetazolamide  (EXP) acetohydrazide  (EXP) acetylsalicylic acid  (EXP,ISO) aflatoxin B1  (ISO) aldosterone  (ISO) amlodipine  (ISO) ammonium chloride  (ISO) Aroclor 1254  (ISO) arsenic atom  (EXP,ISO) arsenic trichloride  (EXP) arsenite(3-)  (EXP,ISO) bacitracin  (ISO) benzene  (ISO) benzo[a]pyrene  (EXP,ISO) benzoic acid  (ISO) bis(2-ethylhexyl) phthalate  (EXP) bisphenol A  (EXP) cadmium atom  (EXP,ISO) cadmium dichloride  (EXP,ISO) cadmium sulfate  (EXP) carboplatin  (ISO) carrageenan  (EXP) cefaloridine  (ISO) cerium trichloride  (EXP) chloroethene  (EXP) chloroprene  (EXP) cholesterol  (EXP) cholic acid  (EXP) choline  (EXP) chromium(6+)  (EXP,ISO) ciguatoxin CTX1B  (EXP) cis-ketoconazole  (ISO) cisplatin  (EXP,ISO) clofibrate  (EXP,ISO) cobalt dichloride  (EXP,ISO) copper atom  (EXP,ISO) copper(0)  (EXP,ISO) copper(2+) sulfate  (EXP,ISO) copper(II) chloride  (ISO) corticosterone  (ISO) coumarin  (ISO) curcumin  (ISO) cycloheximide  (EXP) cytarabine  (ISO) D-glucose  (ISO) daunorubicin  (ISO) Delta(9)-tetrahydrocannabinol  (ISO) dexamethasone  (EXP,ISO) diarsenic trioxide  (ISO) diazoxide  (EXP) dicoumarol  (EXP) diethyl maleate  (ISO) diethylstilbestrol  (EXP,ISO) dimethylarsinic acid  (EXP,ISO) dioxygen  (ISO) diphenylcyclopropenone  (ISO) diquat  (EXP) disodium selenite  (EXP,ISO) dopamine  (EXP) doxorubicin  (EXP,ISO) ethanol  (EXP,ISO) ethylenediaminetetraacetic acid  (EXP) ferroheme b  (EXP,ISO) folic acid  (EXP,ISO) fumonisin B1  (EXP) furan  (ISO) gamma-hexachlorocyclohexane  (ISO) genistein  (EXP) genistein 7-O-beta-D-glucoside  (ISO) glucose  (ISO) glutathione  (EXP,ISO) glycerol  (ISO) griseofulvin  (EXP) hexachlorobenzene  (ISO) hydrogen peroxide  (EXP) hydroquinone  (EXP) hydroxycitronellal  (ISO) iron atom  (ISO) iron trichloride  (ISO) isoprenaline  (EXP) kainic acid  (EXP,ISO) ketamine  (ISO) L-ascorbic acid  (ISO) L-methionine  (EXP) lead diacetate  (EXP,ISO) lipoic acid  (EXP) LY294002  (EXP,ISO) malonaldehyde  (ISO) maneb  (EXP) manganese(II) chloride  (ISO) mercury atom  (EXP,ISO) mercury dichloride  (EXP,ISO) mercury(0)  (EXP,ISO) methapyrilene  (ISO) methotrexate  (ISO) methyl methanesulfonate  (ISO) methylmercury chloride  (EXP) microcystin-LR  (EXP) mono(2-ethylhexyl) phthalate  (EXP) N-acetyl-L-cysteine  (EXP) N-methyl-N'-nitro-N-nitrosoguanidine  (EXP) N-methyl-N-nitrosurea  (EXP) N-nitrosodiethylamine  (EXP,ISO) N-nitrosodimethylamine  (ISO) nickel atom  (EXP) nickel dichloride  (EXP,ISO) nickel sulfate  (EXP,ISO) nitric oxide  (EXP,ISO) nitroprusside  (ISO) ochratoxin A  (ISO) okadaic acid  (EXP) oleanolic acid  (EXP,ISO) ozone  (EXP,ISO) paracetamol  (EXP,ISO) paraquat  (EXP,ISO) parathion  (ISO) pentetic acid  (ISO) phenacetin  (ISO) phenobarbital  (EXP,ISO) phenylhydrazine  (ISO) phorbol 13-acetate 12-myristate  (EXP) phorone  (ISO) phosgene  (EXP) piperonyl butoxide  (ISO) pirinixic acid  (EXP,ISO) potassium chloride  (ISO) potassium dichromate  (EXP,ISO) pregnenolone 16alpha-carbonitrile  (ISO) progesterone  (EXP,ISO) quercetin  (ISO) riddelliine  (ISO) Ro 31-8220  (EXP) rosiglitazone  (EXP,ISO) rotenone  (ISO) S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP,ISO) salicylic acid  (ISO) serotonin  (EXP) silicon dioxide  (EXP) silver atom  (ISO) silver(0)  (ISO) silver(1+) nitrate  (ISO) simvastatin  (ISO) sodium chloride  (ISO) sodium dichromate  (EXP,ISO) sodium dodecyl sulfate  (ISO) spironolactone  (ISO) staurosporine  (EXP) streptozocin  (ISO) succimer  (EXP) sulforaphane  (ISO) tamibarotene  (ISO) tamoxifen  (EXP) tert-butyl hydroperoxide  (EXP) testosterone  (ISO) tetrachloromethane  (EXP,ISO) thapsigargin  (EXP,ISO) thimerosal  (EXP) thioacetamide  (EXP) toluene  (ISO) trichloroethene  (ISO) trichostatin A  (EXP) troglitazone  (ISO) tunicamycin  (EXP) undecane  (ISO) valproic acid  (EXP) vanadium atom  (ISO) vanadium(0)  (ISO) vanadyl sulfate  (ISO) vancomycin  (EXP,ISO) wortmannin  (EXP) zinc atom  (EXP,ISO) zinc dichloride  (EXP,ISO) zinc sulfate  (EXP,ISO) zinc(0)  (EXP,ISO) Gene Ontology Annotations Biological Process cellular metal ion homeostasis  (IDA) cellular response to chromate  (IDA) cellular response to zinc ion  (IDA) cellular zinc ion homeostasis  (IMP) detoxification of copper ion  (IGI) negative regulation of neuron apoptotic process  (IDA) nitric oxide mediated signal transduction  (IMP) Cellular Component cytosol  (IDA) intracellular  (IMP) lysosome  (IDA) Molecular Function copper ion binding  (IDA) metal ion binding  (IDA) zinc ion binding  (TAS) Molecular Pathway Annotations External Database Links KEGG Pathway Mineral absorption Phenotype Annotations abnormal astrocyte morphology  (IAGP) abnormal circulating enzyme level  (IAGP) abnormal compact bone morphology  (IAGP) abnormal hepatocyte morphology  (IAGP) abnormal humoral immune response  (IAGP) abnormal intestinal mineral absorption  (IAGP) abnormal ion homeostasis  (IAGP) abnormal learning/memory/conditioning  (IAGP) abnormal lipid homeostasis  (IAGP) abnormal liver morphology  (IAGP) abnormal long bone epiphyseal ossification zone morphology  (IAGP) abnormal long bone epiphyseal plate morphology  (IAGP) abnormal lymphocyte physiology  (IAGP) abnormal microglial cell morphology  (IAGP) abnormal microglial cell physiology  (IAGP) abnormal pancreas morphology  (IAGP) abnormal physiological response to xenobiotic  (IAGP) abnormal renal glomerulus morphology  (IAGP) abnormal reproductive system physiology  (IAGP) abnormal retinal ganglion layer morphology  (IAGP) abnormal trabecular bone morphology  (IAGP) abnormal zinc homeostasis  (IAGP) astrocytosis  (IAGP) clonic seizures  (IAGP) complete embryonic lethality  (IAGP) complete postnatal lethality  (IAGP) decreased B cell number  (IAGP) decreased body size  (IAGP) decreased bone mass  (IAGP) decreased bone mineral content  (IAGP) decreased compact bone thickness  (IAGP) decreased hepatocyte proliferation  (IAGP) decreased liver regeneration  (IAGP) decreased T cell number  (IAGP) dilated kidney collecting duct  (IAGP) dilated proximal convoluted tubules  (IAGP) enlarged kidney  (IAGP) enlarged liver  (IAGP) enlarged spleen  (IAGP) hemorrhage  (IAGP) hepatic necrosis  (IAGP) impaired wound healing  (IAGP) increased apoptosis  (IAGP) increased blood urea nitrogen level  (IAGP) increased CD4-positive T cell number  (IAGP) increased CD8-positive T cell number  (IAGP) increased circulating alanine transaminase level  (IAGP) increased circulating alkaline phosphatase level  (IAGP) increased glomerular capsule space  (IAGP) increased IgG level  (IAGP) increased IgM level  (IAGP) increased incidence of chemically-induced tumors  (IAGP) increased interleukin-1 beta secretion  (IAGP) increased interleukin-6 secretion  (IAGP) increased lymphocyte cell number  (IAGP) increased macrophage cell number  (IAGP) increased neuron apoptosis  (IAGP) increased neutrophil cell number  (IAGP) increased physiological sensitivity to xenobiotic  (IAGP) increased plasma cell number  (IAGP) increased renal tubule apoptosis  (IAGP) increased sensitivity to induced cell death  (IAGP) increased sensitivity to xenobiotic induced morbidity/mortality  (IAGP) increased spleen weight  (IAGP) increased susceptibility to experimental autoimmune encephalomyelitis  (IAGP) increased susceptibility to injury  (IAGP) increased susceptibility to pharmacologically induced seizures  (IAGP) increased thymocyte apoptosis  (IAGP) increased tumor incidence  (IAGP) increased tumor necrosis factor secretion  (IAGP) increased urine glucose level  (IAGP) kidney atrophy  (IAGP) kidney degeneration  (IAGP) kidney inflammation  (IAGP) liver degeneration  (IAGP) lung inflammation  (IAGP) nephrocalcinosis  (IAGP) no abnormal phenotype detected  (IAGP) oxidative stress  (IAGP) partial embryonic lethality during organogenesis  (IAGP) premature death  (IAGP) renal interstitial fibrosis  (IAGP) renal necrosis  (IAGP) spleen hyperplasia  (IAGP) tonic-clonic seizures  (IAGP) weight loss  (IAGP) References - curated 1. Brambila E, etal., Biol Trace Elem Res. 1999 Nov;70(2):173-82. 2. Ignacio S, etal., Ann N Y Acad Sci. 2005 Aug;1053:121-36. 3. Lanza C, etal., J Neurochem. 2009 Sep;110(5):1674-84. Epub 2009 Jul 8. 4. Lu A, etal., J Cereb Blood Flow Metab. 2006 Feb;26(2):230-52. 5. MGD and Homologene mouse data transfer 6. MGD data from the GO Consortium 7. MGD IEA 8. Morales AI, etal., Toxicol Appl Pharmacol. 2006 Jan 1;210(1-2):128-35. Epub 2005 Oct 14. 9. Piedboeuf B, etal., Am J Respir Cell Mol Biol. 1994 Feb;10(2):123-32. 10. RGD automated import pipeline 11. RGD automated import pipeline for gene-chemical interactions References - uncurated PubMed 10087053   10087067   10099782   10192786   10349636   10413187   10426817   10460198   10495773   10505629   10544001   10614694   10631978   10699757   10736338   10744072   10753647   10764993   10788577   10828279   10830785   10869470   10906280   10922068   10947810   10952993   10966523   11042159   11051100   11076861   11160536   11162523   11172053   11217851   11230134   11298796   11309296   11468771   11578143   11585628   11733576   11771944   11792622   11835189   11850030   11891201   11950277   12098501   12112025   12130647   12388585   12466851   12477932   12613667   12638735   12644021   12700403   12758064   12781987   12801924   12807749   12854659   12861386   1302014   14499492   14525987   14536000   14608409   14610273   14617770   14627804   14692620   14723724   15033980   15039454   15071173   15111301   15131800   15139010   15161632   15247005   15294341   15306638   1535334   1542575   15489334   15520181   1552172   15592854   15606775   15618127   15639482   15735556   15743795   15790531   1588441   15913548   15920153   15979673   16049321   16098087   16126615   16133945   16141072   16141073   16150881   16166738   16329111   16387980   16430929   16432836   1644822   16563532   16600496   16652366   16682017   16750479   1675193   16759633   1686839   16930132   16936113   17008879   17018883   17027170   17031522   17077188   17114818   17222401   17369397   17409522   17435258   17455258   17526490   17543594   17624681   17669619   1779826   1783403   17910954   18054826   18083145   18178676   18221736   18226494   18230604   18239062   1840565   18449439   18483408   18579766   18605988   18799693   18815222   1886768   18929643   18936212   19179618   19254786   19344729   19386279   19490933   19498055   19542206   19583814   19609577   1968046   19828842   19837066   19914257   20056912   20127815   20144643   2019319   20219986   20357188   20371971   2037298   20544854   2067848   20798045   20798270   21035574   21159647   21253395   21267068   21278135   21359432   21467744   21572390   21677750   21866758   21868554   21913972   22152221   22363575   22395140   22523246   22533418   22737085   22766972   22819979   2303527   23132296   2571576   2576352   2725504   2824133   3571489   6095054   6276022   6277322   6356363   6527691   6683708   6935664   6941274   7254320   7613878   7645027   7655347   7733275   7772039   7877445   7878670   7925998   8003488   8026472   8118873   8164679   8290567   8329119   8367468   8404063   8415626   8470112   8495976   8600611   8615771   8617496   8619230   8619234   8640230   8661708   8662221   8683339   8720110   8812413   8824913   8833158   8914622   9069116   9125117   9143490   914867   9169154   9176863   9358851   9379832   9392450   9403069   9419380   9457687   9506445   9512723   9521872   9566988   9582278   9653660   9675420   9801317   9854025 RGD Disease Portals Mt1 has been annotated in the following RGD Disease Portals. Biological Process Cancer Phenotypes Cardiovascular Diseases Cardiovascular Phenotypes Diabetes Diseases Diabetes Phenotypes Immune and Inflammatory Diseases Immune and Inflammatory Phenotypes Neurological Diseases Neurological Phenotypes Obesity Diseases Obesity Phenotypes Respiratory Phenotypes Genomics Comparative Map Data Mt1   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,089 - 94,180,327 + NCBI Mouse cM Map 8 46.34   NCBI Mouse Celera Assembly 8 98,511,203 - 98,512,441 + NCBI Mouse Genome Assembly Build 37 8 96,702,989 - 96,704,227 + NCBI Mouse Genome Assembly Build 36.1 8 96,703,127 - 96,704,224 + NCBI Mouse Cytogenetic Map 8 C5   NCBI MT1A   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 16 57,685,416 - 57,686,839 + NCBI Human Genome Assembly HuRef 16 42,542,032 - 42,543,455 + NCBI Human Genome Assembly GRCh37 16 56,672,578 - 56,673,999 + NCBI Human Genome Assembly Build 36 16 55,230,079 - 55,231,500 + NCBI Human Cytogenetic Map 16 q13   NCBI Human Genome Assembly 16 55,230,081 - 55,231,498   NCBI Mt1a   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 19 p12   NCBI RGSC Genome Assembly v5.0 19 11,277,133 - 11,278,149 - NCBI RGSC Genome Assembly v3.4 19 11,261,631 - 11,262,647 - NCBI Rat Celera Assembly 19 10,711,989 - 10,713,005 - NCBI Genome Assembly 3.1 19 11,266,456 - 11,267,404 - NCBI RH 3.4 19 128.1   RGD Position Markers Mt1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,311 - 94,180,266   UniSTS Mouse cM Map 8 45.0   UniSTS Mouse Celera Assembly 8 98,511,425 - 98,512,380   UniSTS Mouse Genome Assembly Build 37 8 96,703,211 - 96,704,166   UniSTS Mouse Cytogenetic Map 8 C5   UniSTS PMC134057P1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,319 - 94,180,249   UniSTS Mouse cM Map 8 45.0   UniSTS Mouse Celera Assembly 8 98,511,433 - 98,512,363   UniSTS Mouse Genome Assembly Build 37 8 96,703,219 - 96,704,149   UniSTS Mouse Cytogenetic Map 8 C5   UniSTS PMC99995P1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,178,823 - 94,179,040   UniSTS Mouse cM Map 8 45.0   UniSTS Mouse Celera Assembly 8 98,510,937 - 98,511,154   UniSTS Mouse Genome Assembly Build 37 8 96,702,723 - 96,702,940   UniSTS Mouse Cytogenetic Map 8 C5   UniSTS PMC164851P1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,311 - 94,180,151   UniSTS Mouse cM Map 8 45.0   UniSTS Mouse Celera Assembly 8 98,511,425 - 98,512,265   UniSTS Mouse Genome Assembly Build 37 8 96,703,211 - 96,704,051   UniSTS Mouse Cytogenetic Map 8 C5   UniSTS Mt1   Map Chr Position Strand Source Mouse Cytogenetic Map 8 C5   UniSTS Mt1   Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,240 - 94,179,861   UniSTS Mouse Celera Assembly 8 98,511,354 - 98,511,975   UniSTS Mouse Genome Assembly Build 37 8 96,703,140 - 96,703,761   UniSTS Mouse Cytogenetic Map 8 C5   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 4140967 Bmd39_m bone mineral density 39 (mouse) Not determined 8 33127016 119762600 Mouse 1301688 Orch6_m autoimmune orchitis resistance 6 (mouse) Not determined 8 63310749 97310875 Mouse 4141797 Skmw16_m skeletal muscle weight 16 (mouse) Not determined 8 66463446 100463595 Mouse 1357531 Ssta6_m susceptibility to Salmonella typhimurium antigens 6 (mouse) Not determined 8 66463446 100463595 Mouse 1301946 Prxsh_m preaxial shift (mouse) Not determined 8 67433952 101434094 Mouse 1558895 Nsila6_m novelty/stress induced locomotor activation 6 (mouse) Not determined 8 67839067 101839184 Mouse 4142283 Imraq2_m immune response to AAV2 QTL 2 (mouse) Not determined 8 72829274 106829394 Mouse 1301767 Fcsa2_m femoral cross-sectional area 2 (mouse) Not determined 8 72829274 106829394 Mouse 1558780 Idd22_m insulin dependent diabetes susceptibility 22 (mouse) Not determined 8 73626802 107626908 Mouse 4141122 Chlq5_m circulating hormone level QTL 5 (mouse) Not determined 8 73920080 107920292 Mouse 4142484 Vmmt8_m vertebral morphology and mechanical traits 8 (mouse) Not determined 8 73920080 107920292 Mouse 1357647 Fmgty7_m femur geometry 7 (mouse) Not determined 8 73920080 107920292 Mouse 1301872 Cd4ts3_m CD4 T cell subset 3 (mouse) Not determined 8 73920080 107920292 Mouse 1300920 Pitm3_m prion incubation time 3 (mouse) Not determined 8 75726394 109726497 Mouse 1558890 Lith18_m lithogenic gene 18 (mouse) Not determined 8 78199416 112199522 Mouse 1357470 Obq16_m obesity QTL 16 (mouse) Not determined 8 78209247 112209396 Mouse 1301808 Nhdlq1_m non-HDL QTL 1 (mouse) Not determined 8 78209247 112209396 Mouse 1301874 Hdlq16_m HDL QTL 16 (mouse) Not determined 8 78209247 112209396 Mouse 1301099 Cbm2_m cerebellum weight 2 (mouse) Not determined 8 81042513 115042603 Mouse 1301581 Char2_m P. chabaudi malaria resistance QTL 2 (mouse) Not determined 8 81606078 115606303 Mouse 1301766 Desp1_m despair 1 (mouse) Not determined 8 87283476 121283641 Mouse 1302049 Heal1_m wound healing/regeneration 1 (mouse) Not determined 8 88240821 122240969 Mouse 4142492 Hfem2_m Hfe modifier 2 (mouse) Not determined 8 88240821 122240969 Mouse 4142469 Mpvq2_m mean platelet volume locus 2 (mouse) Not determined 8 88240821 122240969 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_013602 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AA050166 (Get FASTA) Search GEO for Microarray Profiles   AAHY01073497 (Get FASTA) Search GEO for Microarray Profiles   AC131733 (Get FASTA) Search GEO for Microarray Profiles   AK007983 (Get FASTA) Search GEO for Microarray Profiles   AK011040 (Get FASTA) Search GEO for Microarray Profiles   AK018727 (Get FASTA) Search GEO for Microarray Profiles   AK154954 (Get FASTA) Search GEO for Microarray Profiles   BC027262 (Get FASTA) Search GEO for Microarray Profiles   BC036990 (Get FASTA) Search GEO for Microarray Profiles   CH466525 (Get FASTA) Search GEO for Microarray Profiles   J00605 (Get FASTA) Search GEO for Microarray Profiles   S62785 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_013602 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_038630 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 8 94,179,089 - 94,180,327 + ENTREZGENE Mouse cM Map 8   + ENTREZGENE Mouse Celera Assembly 8 98,511,203 - 98,512,441 + RGD Mouse Genome Assembly Build 37 8 96,702,989 - 96,704,227 + RGD Protein Sequences Protein RefSeqs NP_038630 (Get FASTA) GenBank Protein AAA39527 (Get FASTA)   AAB26768 (Get FASTA)   AAH27262 (Get FASTA)   AAH36990 (Get FASTA)   BAC25563 (Get FASTA)   BAE32949 (Get FASTA)   EDL11118 (Get FASTA)   EDL11119 (Get FASTA)   P02802 (Get FASTA) Promoters RGD ID: 6843495 Promoter ID: MM_KWN:55320 Type: CpG-Island SO ACC ID: SO:0000170 Source: MPROMDB Tissues & Cell Lines: 3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen Transcripts: NM_013602,   UC009MVX.1 Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 8 96,702,256 - 96,703,217 + MPROMDB RGD ID: 6882508 Promoter ID: EPDNEW_M4705 Type: preliminary Name: Mt1_1 Description: metallothionein 1 SO ACC ID: SO:0000170 Source: EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 8 96,703,135 - 96,703,195   EPDNEW RGD ID: 6850294 Promoter ID: EP07054 Type: single initiation site Name: MM_MT1 Description: Metallothionein I, MT1 gene. SO ACC ID: SO:0000170 Source: EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/) Notes: homology_group=Homology group 138; Mammalian metallothionein Experiment Methods: Nuclease protection with homologous sequence ladder; Nuclease protection with homologous sequence ladder; transfected; or transformed cells Regulation: (induced by or strongly expressed in) heavy metal ions Position: Map Chr Position Strand Source Mouse Genome Assembly Build 36.1 8 96,703,138 - 96,703,198   EPD Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000031765 ENTREZGENE Ensembl Protein ENSMUSP00000034215 ENTREZGENE Ensembl Transcript ENSMUST00000034215 ENTREZGENE Entrez Gene 17748 ENTREZGENE Gene3D-CATH Metallothionein_vert UniProtKB/Swiss-Prot Germonline ENSMUSG00000031765 HomoloGene Group ID 81614 ENTREZGENE InterPro Metalthion_dom UniProtKB/Swiss-Prot   Metalthion_dom_vert UniProtKB/Swiss-Prot   Metalthion_sfam_euk UniProtKB/Swiss-Prot   Metalthion_vert UniProtKB/Swiss-Prot   Metalthion_vert_metal_BS UniProtKB/Swiss-Prot IPI IPI00113696 UniProtKB/Swiss-Prot   IPI00153139 UniProtKB/TrEMBL KEGG Report mmu:17748 ENTREZGENE, UniProtKB/Swiss-Prot MGD MGI:97171 ENTREZGENE PANTHER Metallothionein_vert UniProtKB/Swiss-Prot Pfam Metallothio UniProtKB/Swiss-Prot PRINTS MTVERTEBRATE UniProtKB/Swiss-Prot PROSITE METALLOTHIONEIN_VRT UniProtKB/Swiss-Prot Superfamily-SCOP Metallothionein_sfam UniProtKB/Swiss-Prot UniGene Mm.192991 ENTREZGENE UniProt MT1_MOUSE UniProtKB/Swiss-Prot   Q3U340_MOUSE UniProtKB/TrEMBL   Q8R074_MOUSE UniProtKB/TrEMBL

More on Mt1 Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 10922 Created: 2000-05-25 Species: Mus musculus Last Modified: 2013-04-09 Status: ACTIVE