(1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALPL mRNA CTD PMID:36331819 (E)-thiamethoxam multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [fenugreek seed meal results in increased abundance of Polysaccharides] inhibits the reaction [Thiamethoxam results in decreased activity of ALPL protein] CTD PMID:30621503 (E)-thiamethoxam increases activity ISO Alpl (Rattus norvegicus) 6480464 Thiamethoxam results in increased activity of ALPL protein CTD PMID:30621503 (R,R)-tramadol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Tramadol results in increased expression of ALPL protein] CTD PMID:31618080 (R,R)-tramadol increases expression ISO Alpl (Rattus norvegicus) 6480464 Tramadol results in increased expression of ALPL protein CTD PMID:31618080 (S)-colchicine multiple interactions EXP 6480464 Colchicine inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein] CTD PMID:37573684 (S)-mandelic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Styrene] which results in increased abundance of mandelic acid] which results in increased expression of ALPL protein CTD PMID:34668566 (S)-naringenin multiple interactions ISO ALPL (Homo sapiens) 6480464 [naringenin binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[naringenin binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane multiple interactions ISO ALPL (Homo sapiens) 6480464 o and p'-DDT inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 1,3-dinitrobenzene affects expression ISO Alpl (Rattus norvegicus) 6480464 3-dinitrobenzene affects the expression of ALPL mRNA CTD PMID:24140754 1-(5-isoquinolinesulfonyl)-2-methylpiperazine decreases activity ISO Alpl (Rattus norvegicus) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of ALPL protein CTD PMID:11171635 1-naphthyl isothiocyanate multiple interactions ISO Alpl (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [1-Naphthylisothiocyanate results in increased secretion of ALPL protein] CTD PMID:27702592 1-naphthyl isothiocyanate increases expression ISO Alpl (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of ALPL mRNA CTD PMID:30723492 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ALPL protein CTD PMID:28049044 1-naphthyl isothiocyanate increases secretion ISO Alpl (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased secretion of ALPL protein CTD PMID:27702592 1-naphthyl isothiocyanate multiple interactions EXP 6480464 RAG1 gene mutant form inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ALPL protein] CTD PMID:28049044 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO ALPL (Homo sapiens) 6480464 [Lithocholic Acid co-treated with lysophosphatidic acid] results in increased activity of ALPL protein CTD PMID:19646460 17alpha-ethynylestradiol multiple interactions ISO ALPL (Homo sapiens) 6480464 VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein] CTD PMID:12521655 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with IL17A protein] results in increased secretion of ALPL protein more ... CTD PMID:26040663 and PMID:36329302 17alpha-ethynylestradiol increases secretion EXP 6480464 Ethinyl Estradiol results in increased secretion of ALPL protein CTD PMID:26040663 and PMID:36329302 17beta-estradiol multiple interactions ISO ALPL (Homo sapiens) 6480464 [Estradiol binds to ESR1 protein] which results in increased activity of ALPL protein more ... CTD PMID:12650720 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of ALPL mRNA CTD PMID:15289156 and PMID:19484750 17beta-hydroxy-5alpha-androstan-3-one increases expression EXP 6480464 Dihydrotestosterone results in increased expression of ALPL mRNA CTD PMID:17898587 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO ALPL (Homo sapiens) 6480464 2 more ... CTD PMID:23146750 2,2',5,5'-tetrachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:25795401 2,2',5,5'-tetrachlorobiphenyl decreases expression ISO ALPL (Homo sapiens) 6480464 2 more ... CTD PMID:36804509 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] more ... CTD PMID:22749964 more ... 2,3,7,8-tetrachlorodibenzodioxine increases activity ISO ALPL (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased activity of ALPL protein CTD PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA and Tetrachlorodibenzodioxin results in decreased expression of ALPL protein CTD PMID:22749964 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of ALPL mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO ALPL (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in increased expression of ALPL mRNA and Tetrachlorodibenzodioxin results in increased expression of ALPL protein CTD PMID:18724896 and PMID:30203000 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Alpl (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of ALPL protein] and resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] CTD PMID:11018766 2,3,7,8-tetrachlorodibenzodioxine decreases activity ISO Alpl (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased activity of ALPL protein CTD PMID:11018766 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO ALPL (Homo sapiens) 6480464 Tetrachlorodibenzodioxin affects the expression of ALPL mRNA CTD PMID:20106945 and PMID:36370075 2-acetamidofluorene multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein more ... CTD PMID:15548946 and PMID:15554553 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO ALPL (Homo sapiens) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] CTD PMID:20458730 2-amino-2-deoxy-D-glucopyranose increases expression ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased expression of ALPL mRNA CTD PMID:20458730 2-amino-2-deoxy-D-glucopyranose increases activity ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased activity of ALPL protein CTD PMID:20458730 2-butoxyethanol decreases expression EXP 6480464 n-butoxyethanol results in decreased expression of ALPL mRNA CTD PMID:19812364 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Alpl (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of ALPL protein CTD PMID:25777084 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione decreases activity ISO Alpl (Rattus norvegicus) 6480464 bisindolylmaleimide I results in decreased activity of ALPL protein CTD PMID:11171635 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO ALPL (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ALPL mRNA CTD PMID:28628672 4,4'-diaminodiphenylmethane decreases expression ISO Alpl (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of ALPL protein CTD PMID:11289319 4,4'-sulfonyldiphenol multiple interactions ISO ALPL (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ALPL mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol affects methylation EXP 6480464 bisphenol S affects the methylation of ALPL gene CTD PMID:31683443 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bisphenol S results in decreased expression of ALPL mRNA CTD PMID:33297965 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of ALPL mRNA CTD PMID:28973697 5-(2-methylpiperazine-1-sulfonyl)isoquinoline decreases activity ISO Alpl (Rattus norvegicus) 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine results in decreased activity of ALPL protein CTD PMID:11171635 5-aza-2'-deoxycytidine multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of ALPL mRNA] CTD PMID:23385821 5-aza-2'-deoxycytidine increases expression ISO Alpl (Rattus norvegicus) 6480464 Decitabine results in increased expression of ALPL mRNA CTD PMID:23385821 6-propyl-2-thiouracil increases expression ISO Alpl (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of ALPL mRNA CTD PMID:22504374 and PMID:30047161 6alpha-methylprednisolone increases secretion ISO Alpl (Rattus norvegicus) 6480464 Methylprednisolone results in increased secretion of ALPL protein CTD PMID:30291735 6alpha-methylprednisolone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein] and Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]] CTD PMID:30291735 acephate multiple interactions ISO ALPL (Homo sapiens) 6480464 acephate inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 acetamide increases expression ISO Alpl (Rattus norvegicus) 6480464 acetamide results in increased expression of ALPL mRNA CTD PMID:31881176 acrolein multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrolein] which results in increased abundance of S-(2-carboxyethyl)-N-acetylcysteine] which results in increased expression of ALPL protein and [[Volatile Organic Compounds results in increased abundance of Acrolein] which results in increased abundance of S-(3-hydroxypropyl)cysteine N-acetate] which results in increased expression of ALPL protein CTD PMID:34668566 acrylamide decreases expression ISO Alpl (Rattus norvegicus) 6480464 Acrylamide results in decreased expression of ALPL mRNA CTD PMID:28959563 acrylamide multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrylamide] which results in increased abundance of N-acetyl-S-(2-carbamoylethyl)cysteine] which results in increased expression of ALPL protein CTD PMID:34668566 acrylonitrile multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrylonitrile] which results in increased abundance of N-acetyl-S-(2-cyanoethyl)cysteine] which results in increased expression of ALPL protein CTD PMID:34668566 Actein multiple interactions EXP 6480464 actein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] and actein inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL protein] CTD PMID:28836330 aflatoxin B1 increases secretion EXP 6480464 Aflatoxin B1 results in increased secretion of ALPL protein CTD PMID:37030333 aflatoxin B1 decreases methylation ISO ALPL (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of ALPL intron CTD PMID:30157460 aflatoxin B1 multiple interactions EXP 6480464 fexaramine inhibits the reaction [Aflatoxin B1 results in increased secretion of ALPL protein] CTD PMID:37030333 aflatoxin B1 affects expression ISO ALPL (Homo sapiens) 6480464 Aflatoxin B1 affects the expression of ALPL protein CTD PMID:20106945 alachlor multiple interactions ISO ALPL (Homo sapiens) 6480464 alachlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 aldehydo-D-glucosamine multiple interactions ISO ALPL (Homo sapiens) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] CTD PMID:20458730 aldehydo-D-glucosamine increases expression ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased expression of ALPL mRNA CTD PMID:20458730 aldehydo-D-glucosamine increases activity ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased activity of ALPL protein CTD PMID:20458730 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:33450223 aldehydo-D-glucose decreases expression ISO Alpl (Rattus norvegicus) 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:32643284 aldehydo-D-glucose multiple interactions ISO Alpl (Rattus norvegicus) 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA] CTD PMID:32643284 aldehydo-D-glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]] more ... CTD PMID:33450223 aldosterone increases expression ISO ALPL (Homo sapiens) 6480464 Aldosterone results in increased expression of ALPL mRNA CTD PMID:29149346 aldosterone multiple interactions ISO ALPL (Homo sapiens) 6480464 acephate inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] more ... CTD PMID:29149346 alendronic acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein] and Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]] CTD PMID:30291735 all-trans-retinoic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] more ... CTD PMID:10567916 all-trans-retinoic acid increases expression ISO Alpl (Rattus norvegicus) 6480464 Tretinoin results in increased expression of ALPL mRNA CTD PMID:10022522 and PMID:10567916 all-trans-retinoic acid increases activity ISO Alpl (Rattus norvegicus) 6480464 Tretinoin results in increased activity of ALPL protein CTD PMID:10567916 and PMID:11171635 all-trans-retinoic acid decreases expression ISO ALPL (Homo sapiens) 6480464 Tretinoin results in decreased expression of ALPL mRNA CTD PMID:21934132 all-trans-retinoic acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 EGF protein inhibits the reaction [Tretinoin results in increased activity of ALPL protein] more ... CTD PMID:10567916 and PMID:11171635 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of ALPL mRNA and Tretinoin results in increased expression of ALPL protein CTD PMID:10704935 and PMID:16604517 all-trans-retinoic acid increases activity EXP 6480464 Tretinoin results in increased activity of ALPL protein CTD PMID:10567916 all-trans-retinoic acid multiple interactions EXP 6480464 AGN 193109 inhibits the reaction [Indinavir promotes the reaction [Tretinoin results in increased expression of ALPL protein]] more ... CTD PMID:10567916 and PMID:10704935 all-trans-retinoic acid increases activity ISO ALPL (Homo sapiens) 6480464 Tretinoin results in increased activity of ALPL protein CTD PMID:10567916 allopurinol increases expression ISO Alpl (Rattus norvegicus) 6480464 Allopurinol results in increased expression of ALPL mRNA CTD PMID:26968635 alloxanthine increases expression ISO Alpl (Rattus norvegicus) 6480464 Oxypurinol results in increased expression of ALPL mRNA CTD PMID:26968635 aluminium atom multiple interactions EXP 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA and Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA] CTD PMID:34547296 aluminium oxide increases expression ISO ALPL (Homo sapiens) 6480464 Aluminum Oxide results in increased expression of ALPL mRNA CTD PMID:19464052 aluminium(0) multiple interactions EXP 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA and Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA] CTD PMID:34547296 amitrole increases expression ISO Alpl (Rattus norvegicus) 6480464 Amitrole results in increased expression of ALPL mRNA CTD PMID:30047161 ammonium chloride affects expression ISO Alpl (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of ALPL mRNA CTD PMID:16483693 apocynin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] CTD PMID:24080574 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of ALPL mRNA CTD PMID:25795401 arsane increases expression ISO ALPL (Homo sapiens) 6480464 Arsenic results in increased expression of ALPL protein CTD PMID:30890376 arsenic atom increases expression ISO ALPL (Homo sapiens) 6480464 Arsenic results in increased expression of ALPL protein CTD PMID:30890376 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of ALPL mRNA CTD PMID:33053406 arsenous acid decreases expression ISO Alpl (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of ALPL mRNA CTD PMID:22465848 ATP multiple interactions EXP 6480464 ALPL gene mutant form promotes the reaction [Adenosine Triphosphate results in increased expression of FOS mRNA] CTD PMID:27466191 ATP increases response to substance EXP 6480464 ALPL gene mutant form results in increased susceptibility to Adenosine Triphosphate CTD PMID:27466191 atrazine multiple interactions ISO ALPL (Homo sapiens) 6480464 Atrazine metabolite inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of ALPL mRNA CTD PMID:21567390 and PMID:21569818 benzo[a]pyrene decreases expression ISO ALPL (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of ALPL mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO ALPL (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of ALPL 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO ALPL (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of ALPL promoter CTD PMID:27901495 benzo[e]pyrene decreases methylation ISO ALPL (Homo sapiens) 6480464 benzo(e)pyrene results in decreased methylation of ALPL intron CTD PMID:30157460 beta-D-glucosamine multiple interactions ISO ALPL (Homo sapiens) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] CTD PMID:20458730 beta-D-glucosamine increases expression ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased expression of ALPL mRNA CTD PMID:20458730 beta-D-glucosamine increases activity ISO ALPL (Homo sapiens) 6480464 Glucosamine analog results in increased activity of ALPL protein CTD PMID:20458730 beta-naphthoflavone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of ALPL mRNA CTD PMID:18164116 bexarotene increases expression ISO Alpl (Rattus norvegicus) 6480464 bexarotene results in increased expression of ALPL mRNA CTD PMID:16648578 bezafibrate decreases activity ISO ALPL (Homo sapiens) 6480464 Bezafibrate results in decreased activity of ALPL protein CTD PMID:8102192 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of ALPL mRNA CTD PMID:21499286 bezafibrate multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Bezafibrate results in increased expression of ALPL mRNA] and GSK0660 inhibits the reaction [Bezafibrate results in increased expression of ALPL mRNA] CTD PMID:21499286 bifenthrin multiple interactions ISO ALPL (Homo sapiens) 6480464 bifenthrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 bis(2-ethylhexyl) phthalate decreases expression ISO Alpl (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased expression of ALPL mRNA CTD PMID:22985736 bis(2-ethylhexyl) phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 bis(2-ethylhexyl) phthalate increases expression ISO ALPL (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of ALPL protein CTD PMID:31163220 bisphenol A multiple interactions ISO ALPL (Homo sapiens) 6480464 [bisphenol A binds to ESR1 protein] which results in increased activity of ALPL protein and [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ALPL gene CTD PMID:12650720 and PMID:31601247 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 bisphenol A decreases activity ISO ALPL (Homo sapiens) 6480464 bisphenol A results in decreased activity of ALPL protein CTD PMID:35628159 bisphenol A decreases expression ISO Alpl (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of ALPL mRNA CTD PMID:35192832 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ALPL mRNA CTD PMID:33221593 bisphenol A increases expression ISO Alpl (Rattus norvegicus) 6480464 bisphenol A results in increased expression of ALPL mRNA CTD PMID:25181051 and PMID:32145629 bisphenol A decreases activity EXP 6480464 bisphenol A results in decreased activity of ALPL protein CTD PMID:23900028 bisphenol A decreases expression ISO ALPL (Homo sapiens) 6480464 bisphenol A results in decreased expression of ALPL mRNA CTD PMID:23146750 and PMID:35628159 Butylbenzyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 Butylparaben multiple interactions EXP 6480464 NR3C1 protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA] and PPARG protein promotes the reaction [butylparaben results in decreased expression of ALPL mRNA] CTD PMID:28527915 Butylparaben decreases expression EXP 6480464 butylparaben results in decreased expression of ALPL mRNA CTD PMID:28527915 cadmium atom decreases expression ISO ALPL (Homo sapiens) 6480464 Cadmium results in decreased expression of ALPL mRNA CTD PMID:20570719 cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ALPL mRNA CTD PMID:37325564 cadmium atom multiple interactions ISO ALPL (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ALPL mRNA CTD PMID:32522577 cadmium atom decreases activity ISO Alpl (Rattus norvegicus) 6480464 Cadmium results in decreased activity of ALPL protein CTD PMID:26214600 cadmium atom multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein] and zinc chloride inhibits the reaction [Cadmium results in decreased activity of ALPL protein] CTD PMID:26214600 cadmium dichloride decreases expression ISO ALPL (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of ALPL mRNA CTD PMID:22019892 cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ALPL mRNA CTD PMID:37325564 cadmium dichloride multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Cadmium Chloride results in decreased activity of ALPL protein] and Melatonin inhibits the reaction [Cadmium Chloride results in decreased expression of ALPL mRNA] CTD PMID:31809235 cadmium dichloride decreases activity ISO Alpl (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased activity of ALPL protein CTD PMID:31809235 cadmium dichloride decreases activity ISO ALPL (Homo sapiens) 6480464 Cadmium Chloride results in decreased activity of ALPL protein CTD PMID:27558804 cadmium dichloride decreases expression ISO Alpl (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of ALPL mRNA CTD PMID:22209727 and PMID:31809235 cadmium dichloride multiple interactions ISO ALPL (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cadmium Chloride results in decreased expression of ALPL mRNA] and [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of ALPL mRNA CTD PMID:22019892 and PMID:32522577 caffeine decreases expression ISO Alpl (Rattus norvegicus) 6480464 Caffeine results in decreased expression of ALPL mRNA CTD PMID:30423288 and PMID:31874197 calcidiol increases expression ISO ALPL (Homo sapiens) 6480464 Calcifediol results in increased expression of ALPL mRNA and Calcifediol results in increased expression of ALPL protein CTD PMID:21542014 calcidiol multiple interactions ISO ALPL (Homo sapiens) 6480464 CYP27B1 protein promotes the reaction [Calcifediol results in increased expression of ALPL mRNA] more ... CTD PMID:21542014 calcitriol increases expression ISO ALPL (Homo sapiens) 6480464 Calcitriol results in increased expression of ALPL mRNA and Calcitriol results in increased expression of ALPL protein CTD PMID:12016462 more ... calcitriol multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]] more ... CTD PMID:33450223 calcium dichloride increases expression ISO ALPL (Homo sapiens) 6480464 Calcium Chloride results in increased expression of ALPL mRNA CTD PMID:25824407 calcium dihydroxide increases expression ISO ALPL (Homo sapiens) 6480464 Calcium Hydroxide results in increased expression of ALPL mRNA CTD PMID:22083529 calcium silicate multiple interactions EXP 6480464 [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 cannabidiol increases expression ISO ALPL (Homo sapiens) 6480464 Cannabidiol results in increased expression of ALPL mRNA CTD PMID:33872753 captopril multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Captopril inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of ALPL protein] CTD PMID:27269004 carbon nanotube increases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 carbonyl sulfide decreases expression ISO Alpl (Rattus norvegicus) 6480464 carbonyl sulfide results in decreased expression of ALPL mRNA CTD PMID:19395590 CGP 52608 multiple interactions ISO ALPL (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to ALPL gene] CTD PMID:28238834 chitosan increases expression ISO ALPL (Homo sapiens) 6480464 Chitosan results in increased expression of ALPL mRNA and Chitosan results in increased expression of ALPL protein CTD PMID:25246786 chloramphenicol increases expression ISO ALPL (Homo sapiens) 6480464 Chloramphenicol results in increased expression of ALPL mRNA CTD PMID:22083529 chlorpyrifos multiple interactions EXP 6480464 [cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein and Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein] CTD PMID:15991261 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of ALPL mRNA CTD PMID:37019170 chromium atom decreases activity ISO Alpl (Rattus norvegicus) 6480464 Chromium results in decreased activity of ALPL protein CTD PMID:16866188 chromium(3+) trichloride multiple interactions EXP 6480464 [cobaltous chloride co-treated with chromic chloride] results in decreased expression of ALPL protein CTD PMID:25966675 chromium(3+) trichloride decreases expression EXP 6480464 chromic chloride results in decreased expression of ALPL protein CTD PMID:25966675 clofibrate increases expression EXP 6480464 Clofibrate results in increased expression of ALPL mRNA CTD PMID:23811191 clofibric acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ALPL mRNA CTD PMID:17602206 cobalt dichloride multiple interactions ISO ALPL (Homo sapiens) 6480464 cobaltous chloride affects the reaction [BMP2 protein results in increased expression of ALPL mRNA] more ... CTD PMID:21882223 and PMID:26054564 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of ALPL mRNA and cobaltous chloride results in decreased expression of ALPL protein CTD PMID:16772336 and PMID:25966675 cobalt dichloride multiple interactions EXP 6480464 [cobaltous chloride co-treated with chromic chloride] results in decreased expression of ALPL protein more ... CTD PMID:23203800 and PMID:25966675 cobalt dichloride decreases expression ISO ALPL (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of ALPL protein CTD PMID:21882223 copper atom increases expression ISO Alpl (Rattus norvegicus) 6480464 Copper results in increased expression of ALPL mRNA CTD PMID:30556269 copper(0) increases expression ISO Alpl (Rattus norvegicus) 6480464 Copper results in increased expression of ALPL mRNA CTD PMID:30556269 cordycepin multiple interactions ISO ALPL (Homo sapiens) 6480464 cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]] CTD PMID:34575692 cordycepin increases expression EXP 6480464 cordycepin results in increased expression of ALPL protein CTD PMID:32042022 corticosterone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of ALPL mRNA] CTD PMID:30423288 corticosterone decreases expression ISO Alpl (Rattus norvegicus) 6480464 Corticosterone results in decreased expression of ALPL mRNA CTD PMID:30423288 coumestrol multiple interactions ISO ALPL (Homo sapiens) 6480464 [Coumestrol binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[Coumestrol binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 cyanuric acid increases expression ISO Alpl (Rattus norvegicus) 6480464 cyanuric acid results in increased expression of ALPL protein CTD PMID:36152796 cyclosporin A decreases expression ISO ALPL (Homo sapiens) 6480464 Cyclosporine results in decreased expression of ALPL mRNA CTD PMID:20106945 cyclosporin A increases expression ISO ALPL (Homo sapiens) 6480464 Cyclosporine results in increased expression of ALPL protein CTD PMID:1790624 cypermethrin multiple interactions EXP 6480464 [cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein and Plant Extracts inhibits the reaction [[cypermethrin co-treated with Chlorpyrifos] results in increased expression of ALPL protein] CTD PMID:15991261 cypermethrin multiple interactions ISO ALPL (Homo sapiens) 6480464 cypermethrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 cypermethrin increases activity ISO Alpl (Rattus norvegicus) 6480464 cypermethrin results in increased activity of ALPL protein CTD PMID:15365239 D-glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]] more ... CTD PMID:33450223 D-glucose multiple interactions ISO Alpl (Rattus norvegicus) 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA] CTD PMID:32643284 D-glucose decreases expression ISO Alpl (Rattus norvegicus) 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:32643284 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:33450223 daidzein multiple interactions ISO ALPL (Homo sapiens) 6480464 [daidzein binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[daidzein binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 DDE multiple interactions ISO ALPL (Homo sapiens) 6480464 Dichlorodiphenyl Dichloroethylene inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 DDT multiple interactions ISO ALPL (Homo sapiens) 6480464 DDT inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 decabromodiphenyl ether decreases expression ISO Alpl (Rattus norvegicus) 6480464 decabromobiphenyl ether results in decreased expression of ALPL mRNA CTD PMID:23640034 desferrioxamine B decreases expression EXP 6480464 Deferoxamine results in decreased expression of ALPL mRNA CTD PMID:16772336 desferrioxamine B multiple interactions ISO ALPL (Homo sapiens) 6480464 Indomethacin promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] and Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] CTD PMID:21882223 desferrioxamine B decreases expression ISO ALPL (Homo sapiens) 6480464 Deferoxamine results in decreased expression of ALPL protein CTD PMID:21882223 dexamethasone multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA more ... CTD PMID:15270777 and PMID:26492236 dexamethasone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of ALPL protein] CTD PMID:28363435 dexamethasone decreases expression ISO Alpl (Rattus norvegicus) 6480464 Dexamethasone results in decreased expression of ALPL protein CTD PMID:28363435 dexamethasone multiple interactions ISO ALPL (Homo sapiens) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA more ... CTD PMID:26424790 more ... dexamethasone increases expression ISO ALPL (Homo sapiens) 6480464 Dexamethasone results in increased expression of ALPL mRNA CTD PMID:27608943 dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALPL mRNA CTD PMID:29950665 dextran sulfate increases activity EXP 6480464 Dextran Sulfate results in increased activity of ALPL protein CTD PMID:30489199 Di-n-octyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 diallyl trisulfide increases expression ISO ALPL (Homo sapiens) 6480464 diallyl trisulfide results in increased expression of ALPL protein CTD PMID:19550292 diarsenic trioxide decreases expression ISO Alpl (Rattus norvegicus) 6480464 Arsenic Trioxide results in decreased expression of ALPL mRNA CTD PMID:22465848 dibenz[a,h]anthracene increases expression EXP 6480464 1 more ... CTD PMID:26377693 dibutyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 dichloroacetic acid increases expression EXP 6480464 Dichloroacetic Acid results in increased expression of ALPL mRNA CTD PMID:28962523 diethyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of ALPL mRNA CTD PMID:15289156 and PMID:15591538 difenoconazole multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [difenoconazole results in increased activity of ALPL protein] CTD PMID:28679351 difenoconazole increases activity ISO Alpl (Rattus norvegicus) 6480464 difenoconazole results in increased activity of ALPL protein CTD PMID:28679351 digoxin multiple interactions EXP 6480464 Digoxin inhibits the reaction [Ethinyl Estradiol results in increased secretion of ALPL protein] CTD PMID:36329302 Diisodecyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 diisononyl phthalate multiple interactions EXP 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ALPL protein CTD PMID:35739755 dimethoate multiple interactions ISO ALPL (Homo sapiens) 6480464 Dimethoate inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ALPL mRNA and Oxygen deficiency inhibits the reaction [LIF protein affects the reaction ALPL mRNA] CTD PMID:26723917 and PMID:30529165 dioxygen increases expression ISO ALPL (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of ALPL mRNA CTD PMID:26516004 diquat increases expression EXP 6480464 Diquat results in increased expression of ALPL mRNA CTD PMID:36851058 diuron decreases expression ISO Alpl (Rattus norvegicus) 6480464 Diuron results in decreased expression of ALPL mRNA CTD PMID:25152437 diuron increases expression ISO Alpl (Rattus norvegicus) 6480464 Diuron results in increased expression of ALPL mRNA CTD PMID:21551480 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Bezafibrate results in increased expression of ALPL mRNA] CTD PMID:21499286 dorsomorphin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 dorsomorphin inhibits the reaction [1-Naphthylisothiocyanate results in increased secretion of ALPL protein] CTD PMID:27702592 doxorubicin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Doxorubicin results in decreased activity of ALPL protein] and Vitamin E inhibits the reaction [Doxorubicin results in decreased activity of ALPL protein] CTD PMID:32810592 doxorubicin decreases activity ISO Alpl (Rattus norvegicus) 6480464 Doxorubicin results in decreased activity of ALPL protein CTD PMID:32810592 enalapril multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Enalapril inhibits the reaction [Corticosterone results in decreased expression of ALPL mRNA] and Enalapril inhibits the reaction [Ethanol results in decreased expression of ALPL mRNA] CTD PMID:30423288 and PMID:31887396 endosulfan increases expression ISO Alpl (Rattus norvegicus) 6480464 Endosulfan results in increased expression of ALPL mRNA CTD PMID:29391264 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of ALPL mRNA CTD PMID:35436446 ethanol decreases expression ISO ALPL (Homo sapiens) 6480464 Ethanol results in decreased expression of ALPL mRNA CTD PMID:23378141 ethanol increases expression ISO Alpl (Rattus norvegicus) 6480464 Ethanol results in increased expression of ALPL protein CTD PMID:36453646 ethanol decreases expression ISO Alpl (Rattus norvegicus) 6480464 Ethanol results in decreased expression of ALPL mRNA CTD PMID:31887396 ethanol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Cannabinoids inhibits the reaction [Ethanol results in increased expression of ALPL protein] and Enalapril inhibits the reaction [Ethanol results in decreased expression of ALPL mRNA] CTD PMID:31887396 and PMID:36453646 ethanol increases expression EXP 6480464 Ethanol results in increased expression of ALPL mRNA CTD PMID:30319688 ethanol multiple interactions ISO ALPL (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in decreased expression of ALPL mRNA CTD PMID:23378141 eugenol increases expression ISO ALPL (Homo sapiens) 6480464 Eugenol results in increased expression of ALPL mRNA CTD PMID:22083529 Falecalcitriol increases expression ISO ALPL (Homo sapiens) 6480464 26 more ... CTD PMID:12016462 fenofibrate decreases expression ISO ALPL (Homo sapiens) 6480464 Fenofibrate results in decreased expression of ALPL mRNA CTD PMID:25572481 fenvalerate multiple interactions ISO ALPL (Homo sapiens) 6480464 fenvalerate inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] and fenvalerate inhibits the reaction [Progesterone results in increased activity of ALPL protein] CTD PMID:16326432 and PMID:29149346 fenvalerate increases activity ISO Alpl (Rattus norvegicus) 6480464 fenvalerate results in increased activity of ALPL protein CTD PMID:15696646 ferric ammonium citrate multiple interactions EXP 6480464 ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein and Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein] CTD PMID:36087815 Fexaramine multiple interactions EXP 6480464 fexaramine inhibits the reaction [Aflatoxin B1 results in increased secretion of ALPL protein] CTD PMID:37030333 fipronil multiple interactions ISO ALPL (Homo sapiens) 6480464 fipronil inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 fisetin increases expression ISO Alpl (Rattus norvegicus) 6480464 fisetin results in increased expression of ALPL mRNA CTD PMID:37087476 folic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 [Ethanol co-treated with Folic Acid] results in decreased expression of ALPL mRNA CTD PMID:23378141 formaldehyde increases expression ISO ALPL (Homo sapiens) 6480464 Formaldehyde results in increased expression of ALPL mRNA CTD PMID:22083529 fulvestrant multiple interactions ISO ALPL (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of ALPL gene more ... CTD PMID:12650720 and PMID:31601247 furan increases expression ISO Alpl (Rattus norvegicus) 6480464 furan results in increased expression of ALPL mRNA CTD PMID:25539665 and PMID:26194646 gallocatechin increases expression ISO Alpl (Rattus norvegicus) 6480464 gallocatechol results in increased expression of ALPL mRNA CTD PMID:21877759 gamma-aminobutyric acid decreases abundance EXP 6480464 ALPL gene mutant form results in decreased abundance of gamma-Aminobutyric Acid CTD PMID:7550313 gamma-hexachlorocyclohexane multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Hexachlorocyclohexane co-treated with isoproturon] results in decreased activity of ALPL protein and [Hexachlorocyclohexane co-treated with isoproturon] results in increased expression of ALPL protein CTD PMID:11180283 gamma-hexachlorocyclohexane increases expression ISO Alpl (Rattus norvegicus) 6480464 Hexachlorocyclohexane results in increased expression of ALPL protein CTD PMID:11180283 gamma-hexachlorocyclohexane increases activity ISO Alpl (Rattus norvegicus) 6480464 Hexachlorocyclohexane results in increased activity of ALPL protein CTD PMID:11180283 genistein multiple interactions ISO ALPL (Homo sapiens) 6480464 [Genistein binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[Genistein binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 genistein multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of ALPL mRNA CTD PMID:21782745 genistein increases expression EXP 6480464 Genistein results in increased expression of ALPL mRNA CTD PMID:15289156 glucose multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]] more ... CTD PMID:33450223 glucose decreases expression ISO Alpl (Rattus norvegicus) 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:32643284 glucose multiple interactions ISO Alpl (Rattus norvegicus) 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA] CTD PMID:32643284 glucose decreases expression EXP 6480464 Glucose results in decreased expression of ALPL mRNA CTD PMID:33450223 glycerol 2-phosphate increases hydrolysis ISO ALPL (Homo sapiens) 6480464 ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid CTD PMID:18500657 glycerol 2-phosphate multiple interactions EXP 6480464 [ALPL protein results in increased degradation of beta-glycerophosphoric acid] which results in increased abundance of Phosphates more ... CTD PMID:17383965 and PMID:26492236 glycerol 2-phosphate increases expression ISO ALPL (Homo sapiens) 6480464 beta-glycerophosphoric acid results in increased expression of ALPL mRNA CTD PMID:18500657 glycerol 2-phosphate increases degradation EXP 6480464 ALPL protein results in increased degradation of beta-glycerophosphoric acid CTD PMID:17383965 glycerol 2-phosphate increases activity ISO ALPL (Homo sapiens) 6480464 beta-glycerophosphoric acid results in increased activity of ALPL protein CTD PMID:18500657 glycerol 2-phosphate multiple interactions ISO ALPL (Homo sapiens) 6480464 [ALPL protein results in increased hydrolysis of beta-glycerophosphoric acid] which results in increased abundance of Phosphates more ... CTD PMID:18500657 more ... glycyrrhetinate multiple interactions EXP 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein] more ... CTD PMID:21910061 glycyrrhetinic acid multiple interactions EXP 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [BMP2 protein results in increased activity of ALPL protein] more ... CTD PMID:21910061 guggulsterone multiple interactions EXP 6480464 pregna-4 more ... CTD PMID:37573684 GW 4064 increases expression EXP 6480464 GW 4064 results in increased expression of ALPL mRNA CTD PMID:26655953 hexachlorobenzene increases activity ISO Alpl (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased activity of ALPL protein CTD PMID:30064338 hexachlorobenzene multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Hexachlorobenzene results in increased activity of ALPL protein] CTD PMID:30064338 hexadecanoic acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 acetovanillone inhibits the reaction [Palmitic Acid results in increased expression of ALPL mRNA] more ... CTD PMID:24080574 hexadecanoic acid increases expression ISO Alpl (Rattus norvegicus) 6480464 Palmitic Acid results in increased expression of ALPL mRNA CTD PMID:24080574 hexane decreases methylation ISO Alpl (Rattus norvegicus) 6480464 n-hexane results in decreased methylation of ALPL promoter CTD PMID:23740543 hydrogen peroxide decreases expression ISO ALPL (Homo sapiens) 6480464 Hydrogen Peroxide results in decreased expression of ALPL mRNA CTD PMID:25130202 hydrogen peroxide multiple interactions EXP 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of ALPL mRNA CTD PMID:25130202 hydrogen peroxide multiple interactions ISO ALPL (Homo sapiens) 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 hydroxychloroquine affects expression ISO ALPL (Homo sapiens) 6480464 Hydroxychloroquine affects the expression of ALPL mRNA CTD PMID:28975700 hydroxychloroquine multiple interactions ISO ALPL (Homo sapiens) 6480464 Hydroxychloroquine affects the reaction [Simvastatin affects the expression of ALPL mRNA] CTD PMID:28975700 icariside II increases expression ISO Alpl (Rattus norvegicus) 6480464 baohuoside I results in increased expression of ALPL mRNA CTD PMID:17764702 icariside II increases secretion EXP 6480464 baohuoside I results in increased secretion of ALPL protein CTD PMID:35802278 Icaritin increases expression ISO Alpl (Rattus norvegicus) 6480464 icaritin results in increased expression of ALPL mRNA CTD PMID:17764702 indinavir multiple interactions EXP 6480464 AGN 193109 inhibits the reaction [Indinavir promotes the reaction [Tretinoin results in increased expression of ALPL protein]] and Indinavir promotes the reaction [Tretinoin results in increased expression of ALPL protein] CTD PMID:10704935 indole-3-methanol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 indole-3-carbinol affects the reaction [Thioacetamide results in increased expression of ALPL protein] CTD PMID:37150287 indometacin multiple interactions ISO ALPL (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of ALPL mRNA more ... CTD PMID:21882223 and PMID:28628672 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of ALPL mRNA CTD PMID:36331819 isocyanuric acid increases expression ISO Alpl (Rattus norvegicus) 6480464 cyanuric acid results in increased expression of ALPL protein CTD PMID:36152796 isoniazide increases activity EXP 6480464 Isoniazid results in increased activity of ALPL protein CTD PMID:25886055 isoniazide multiple interactions EXP 6480464 [Rifampin co-treated with Isoniazid] results in increased activity of ALPL protein CTD PMID:25886055 isoproturon multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Hexachlorocyclohexane co-treated with isoproturon] results in decreased activity of ALPL protein and [Hexachlorocyclohexane co-treated with isoproturon] results in increased expression of ALPL protein CTD PMID:11180283 ketoconazole multiple interactions ISO ALPL (Homo sapiens) 6480464 Ketoconazole inhibits the reaction [Calcifediol results in increased expression of ALPL mRNA] CTD PMID:21542014 ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of ALPL protein CTD PMID:31099283 L-ascorbic acid increases expression ISO ALPL (Homo sapiens) 6480464 Ascorbic Acid results in increased expression of ALPL mRNA CTD PMID:28105418 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of ALPL mRNA more ... CTD PMID:26492236 L-ascorbic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 [Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA and EZH2 protein inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA] CTD PMID:26424790 L-ascorbic acid 2-phosphate multiple interactions ISO ALPL (Homo sapiens) 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein more ... CTD PMID:34575692 lead diacetate decreases expression ISO Alpl (Rattus norvegicus) 6480464 lead acetate results in decreased expression of ALPL protein CTD PMID:21712424 lead(0) decreases expression EXP 6480464 Lead results in decreased expression of ALPL mRNA CTD PMID:23086611 levamisole multiple interactions ISO ALPL (Homo sapiens) 6480464 Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased activity of ALPL protein] and Levamisole inhibits the reaction [beta-glycerophosphoric acid results in increased expression of ALPL mRNA] CTD PMID:18500657 levamisole multiple interactions EXP 6480464 [ALPL gene mutant form results in increased susceptibility to Levamisole] which results in increased expression of FOS mRNA CTD PMID:27466191 levamisole decreases activity EXP 6480464 Levamisole results in decreased activity of ALPL protein CTD PMID:27466191 levamisole increases response to substance EXP 6480464 ALPL gene mutant form results in increased susceptibility to Levamisole CTD PMID:27466191 levonorgestrel multiple interactions ISO ALPL (Homo sapiens) 6480464 VDR gene polymorphism affects the reaction [[Ethinyl Estradiol co-treated with Levonorgestrel] affects the expression of ALPL protein] CTD PMID:12521655 lipopolysaccharide multiple interactions ISO ALPL (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ALPL mRNA CTD PMID:35811015 lipopolysaccharide multiple interactions EXP 6480464 Lipopolysaccharides inhibits the reaction [[angelicae sinensis extract co-treated with asarum oil analog] results in increased expression of ALPL mRNA] and Lipopolysaccharides inhibits the reaction [[angelicae sinensis extract co-treated with asarum oil analog] results in increased expression of ALPL protein] CTD PMID:38139216 lithocholic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 [Lithocholic Acid co-treated with lysophosphatidic acid] results in increased activity of ALPL protein and EGF protein promotes the reaction [Lithocholic Acid results in increased activity of ALPL protein] CTD PMID:19646460 loliolide increases expression ISO ALPL (Homo sapiens) 6480464 loliolide results in increased expression of ALPL mRNA CTD PMID:31601058 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL protein]] CTD PMID:33450223 mandelic acid multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Styrene] which results in increased abundance of mandelic acid] which results in increased expression of ALPL protein CTD PMID:34668566 melatonin increases expression ISO ALPL (Homo sapiens) 6480464 Melatonin results in increased expression of ALPL mRNA CTD PMID:20738756 melatonin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Cadmium Chloride results in decreased activity of ALPL protein] and Melatonin inhibits the reaction [Cadmium Chloride results in decreased expression of ALPL mRNA] CTD PMID:31809235 menadione decreases secretion EXP 6480464 Vitamin K 3 results in decreased secretion of ALPL protein CTD PMID:30453296 menaquinone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 PTH protein promotes the reaction [Vitamin K 2 results in increased expression of ALPL protein] and Vitamin K 2 affects the reaction [PTH protein results in increased expression of ALPL protein] CTD PMID:30639440 menaquinone increases expression ISO Alpl (Rattus norvegicus) 6480464 Vitamin K 2 results in increased expression of ALPL protein CTD PMID:30639440 menaquinone-4 increases activity EXP 6480464 menatetrenone results in increased activity of ALPL protein CTD PMID:11113387 metformin multiple interactions ISO ALPL (Homo sapiens) 6480464 Metformin inhibits the reaction [BMP2 protein results in increased expression of ALPL mRNA] CTD PMID:37409753 methapyrilene decreases methylation ISO ALPL (Homo sapiens) 6480464 Methapyrilene results in decreased methylation of ALPL intron CTD PMID:30157460 methimazole increases expression ISO Alpl (Rattus norvegicus) 6480464 Methimazole results in increased expression of ALPL mRNA CTD PMID:22504374 and PMID:30047161 methotrexate multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Captopril inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of ALPL protein] more ... CTD PMID:27269004 methoxychlor multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of ALPL mRNA CTD PMID:21782745 methoxychlor multiple interactions ISO ALPL (Homo sapiens) 6480464 Methoxychlor inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 methylparaben decreases expression EXP 6480464 methylparaben results in decreased expression of ALPL mRNA CTD PMID:28527915 microcystin-LR increases activity ISO Alpl (Rattus norvegicus) 6480464 cyanoginosin LR results in increased activity of ALPL protein CTD PMID:36657700 microcystin-LR increases expression ISO Alpl (Rattus norvegicus) 6480464 cyanoginosin LR results in increased expression of ALPL protein CTD PMID:37467923 mono(2-ethylhexyl) phthalate decreases expression EXP 6480464 mono-(2-ethylhexyl)phthalate analog results in decreased expression of ALPL protein and mono-(2-ethylhexyl)phthalate results in decreased expression of ALPL protein CTD PMID:25777084 Morroniside multiple interactions ISO Alpl (Rattus norvegicus) 6480464 morroniside inhibits the reaction [Glucose results in decreased expression of ALPL mRNA] CTD PMID:32643284 Morroniside increases expression EXP 6480464 morroniside results in increased expression of ALPL mRNA CTD PMID:34638983 and PMID:35848187 Moxestrol multiple interactions EXP 6480464 alisol B 23-acetate inhibits the reaction [moxestrol results in increased secretion of ALPL protein] CTD PMID:26040663 Muraglitazar increases expression ISO Alpl (Rattus norvegicus) 6480464 muraglitazar results in increased expression of ALPL mRNA CTD PMID:21515302 myricitrin multiple interactions EXP 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 myricitrin multiple interactions ISO ALPL (Homo sapiens) 6480464 myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP 6480464 [zinc chloride deficiency co-treated with N more ... CTD PMID:19913120 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA] CTD PMID:34547296 N-Acetyl-S- (3-hydroxypropyl)-cysteine multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrolein] which results in increased abundance of S-(3-hydroxypropyl)cysteine N-acetate] which results in increased expression of ALPL protein CTD PMID:34668566 N-Acetyl-S-(2-carbamoylethyl)-cysteine multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrylamide] which results in increased abundance of N-acetyl-S-(2-carbamoylethyl)cysteine] which results in increased expression of ALPL protein CTD PMID:34668566 N-Acetyl-S-(2-cyanoethyl)-cysteine multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Acrylonitrile] which results in increased abundance of N-acetyl-S-(2-cyanoethyl)cysteine] which results in increased expression of ALPL protein CTD PMID:34668566 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of ALPL protein CTD PMID:26558463 N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO ALPL (Homo sapiens) 6480464 Methylnitronitrosoguanidine results in increased expression of ALPL mRNA CTD PMID:12634122 N-nitrosodiethylamine multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in increased activity of ALPL protein more ... CTD PMID:15548946 more ... N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions EXP 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] CTD PMID:10567916 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] CTD PMID:10567916 N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions ISO ALPL (Homo sapiens) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] CTD PMID:10567916 naphthalene increases expression EXP 6480464 naphthalene results in increased expression of ALPL mRNA CTD PMID:18978301 nebivolol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Nebivolol promotes the reaction [Alendronate inhibits the reaction [Methylprednisolone results in increased secretion of ALPL protein]] CTD PMID:30291735 niclosamide decreases expression EXP 6480464 Niclosamide results in decreased expression of ALPL mRNA CTD PMID:28824321 Nonylphenol multiple interactions ISO ALPL (Homo sapiens) 6480464 [nonylphenol binds to ESR1 protein] which results in increased activity of ALPL protein CTD PMID:12650720 ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of ALPL protein CTD PMID:35543154 orphenadrine affects expression ISO Alpl (Rattus norvegicus) 6480464 Orphenadrine affects the expression of ALPL mRNA CTD PMID:23665939 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of ALPL mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of ALPL mRNA CTD PMID:34911549 pamidronate increases expression ISO ALPL (Homo sapiens) 6480464 pamidronate results in increased expression of ALPL protein CTD PMID:11683535 paracetamol increases expression ISO Alpl (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of ALPL mRNA CTD PMID:19784758 paracetamol decreases expression ISO ALPL (Homo sapiens) 6480464 Acetaminophen results in decreased expression of ALPL mRNA CTD PMID:21420995 and PMID:29067470 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of ALPL mRNA CTD PMID:17562736 paraquat decreases expression ISO Alpl (Rattus norvegicus) 6480464 Paraquat results in decreased expression of ALPL mRNA CTD PMID:32680482 paricalcitol multiple interactions ISO ALPL (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of ALPL mRNA CTD PMID:17715259 perfluoroheptanoic acid increases expression EXP 6480464 perfluoro-n-heptanoic acid results in increased expression of ALPL protein CTD PMID:36435305 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of ALPL protein CTD PMID:29694846 perfluorononanoic acid decreases expression ISO ALPL (Homo sapiens) 6480464 perfluoro-n-nonanoic acid results in decreased expression of ALPL mRNA CTD PMID:32588087 perfluorooctane-1-sulfonic acid increases expression ISO Alpl (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of ALPL mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of ALPL mRNA more ... CTD PMID:36331819 perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of ALPL protein CTD PMID:26178269 perfluorooctane-1-sulfonic acid affects expression ISO ALPL (Homo sapiens) 6480464 perfluorooctane sulfonic acid affects the expression of ALPL mRNA CTD PMID:30738844 perfluorooctanoic acid increases expression ISO Alpl (Rattus norvegicus) 6480464 perfluorooctanoic acid results in increased expression of ALPL mRNA and perfluorooctanoic acid results in increased expression of ALPL protein CTD PMID:19162173 more ... perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of ALPL protein CTD PMID:36435305 perfluorooctanoic acid decreases expression ISO ALPL (Homo sapiens) 6480464 perfluorooctanoic acid results in decreased expression of ALPL mRNA CTD PMID:23146750 permethrin multiple interactions ISO ALPL (Homo sapiens) 6480464 Permethrin inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] and Permethrin inhibits the reaction [Progesterone results in increased activity of ALPL protein] CTD PMID:16326432 and PMID:29149346 phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein] CTD PMID:18436364 phenethyl caffeate multiple interactions ISO Alpl (Rattus norvegicus) 6480464 caffeic acid phenethyl ester inhibits the reaction [Dexamethasone results in decreased expression of ALPL protein] CTD PMID:28363435 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of ALPL mRNA CTD PMID:19482888 phenobarbital multiple interactions EXP 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of ALPL mRNA] CTD PMID:19482888 phenol increases expression ISO ALPL (Homo sapiens) 6480464 Phenol results in increased expression of ALPL mRNA CTD PMID:22083529 phosphorus atom multiple interactions ISO ALPL (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of ALPL mRNA CTD PMID:17715259 phosphorus(.) multiple interactions ISO ALPL (Homo sapiens) 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of ALPL mRNA CTD PMID:17715259 phytoestrogen increases activity ISO ALPL (Homo sapiens) 6480464 Phytoestrogens results in increased activity of ALPL protein CTD PMID:16019205 phytoestrogen increases expression ISO ALPL (Homo sapiens) 6480464 Phytoestrogens results in increased expression of ALPL mRNA CTD PMID:16019205 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of ALPL mRNA and pirinixic acid results in increased expression of ALPL protein CTD PMID:19176532 more ... pirinixic acid increases expression ISO Alpl (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of ALPL mRNA CTD PMID:19162173 pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of ALPL mRNA] and RXRA protein promotes the reaction [pirinixic acid results in increased expression of ALPL protein] CTD PMID:19176532 and PMID:20059764 potassium dichromate decreases activity ISO Alpl (Rattus norvegicus) 6480464 Potassium Dichromate results in decreased activity of ALPL protein CTD PMID:16866188 procaine increases expression ISO ALPL (Homo sapiens) 6480464 Procaine results in increased expression of ALPL mRNA CTD PMID:22083529 progesterone multiple interactions ISO ALPL (Homo sapiens) 6480464 [Estradiol co-treated with Progesterone] results in increased expression of ALPL mRNA more ... CTD PMID:16326432 more ... progesterone decreases expression ISO ALPL (Homo sapiens) 6480464 Progesterone results in decreased expression of ALPL mRNA CTD PMID:21540246 progesterone increases expression ISO ALPL (Homo sapiens) 6480464 Progesterone results in increased expression of ALPL mRNA CTD PMID:17404688 progesterone increases activity ISO ALPL (Homo sapiens) 6480464 Progesterone results in increased activity of ALPL protein CTD PMID:16326432 pyridoxal 5'-phosphate increases abundance EXP 6480464 ALPL gene mutant form results in increased abundance of Pyridoxal Phosphate CTD PMID:7550313 pyrogallol increases expression EXP 6480464 Pyrogallol results in increased expression of ALPL mRNA CTD PMID:20362636 pyrrolidine dithiocarbamate multiple interactions ISO ALPL (Homo sapiens) 6480464 cordycepin inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein]] and pyrrolidine dithiocarbamic acid inhibits the reaction [[Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid] results in increased activity of ALPL protein] CTD PMID:34575692 quercetin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of ALPL protein] more ... CTD PMID:26053266 more ... quercetin increases expression ISO Alpl (Rattus norvegicus) 6480464 Quercetin results in increased expression of ALPL protein CTD PMID:26053266 raloxifene multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Raloxifene Hydrochloride inhibits the reaction [Decitabine results in increased expression of ALPL mRNA] CTD PMID:23385821 ramipril multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Ramipril inhibits the reaction [Carbon Tetrachloride results in increased expression of ALPL protein] CTD PMID:26862777 resveratrol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased activity of ALPL protein] and resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] CTD PMID:11018766 rifampicin multiple interactions EXP 6480464 [Rifampin co-treated with Isoniazid] results in increased activity of ALPL protein CTD PMID:25886055 rifampicin increases activity EXP 6480464 Rifampin results in increased activity of ALPL protein CTD PMID:25886055 S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO ALPL (Homo sapiens) 6480464 [S-(1 and 2-dichlorovinyl)cysteine affects the susceptibility to Lipopolysaccharides] which results in increased expression of ALPL mRNA CTD PMID:35811015 Salidroside increases activity EXP 6480464 rhodioloside results in increased activity of ALPL protein CTD PMID:24055767 Salidroside increases expression EXP 6480464 rhodioloside results in increased expression of ALPL mRNA CTD PMID:24055767 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [(4-(7-chloroquinolin-4-yl)piperazino)(1-phenyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methanone promotes the reaction [BMP2 protein results in increased expression of ALPL mRNA]] CTD PMID:25789987 SB 431542 multiple interactions ISO ALPL (Homo sapiens) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] CTD PMID:20458730 silibinin multiple interactions EXP 6480464 Silybin inhibits the reaction [ferric ammonium citrate results in decreased expression of and results in decreased activity of ALPL protein] CTD PMID:36087815 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of ALPL mRNA CTD PMID:29341224 simvastatin multiple interactions ISO ALPL (Homo sapiens) 6480464 Hydroxychloroquine affects the reaction [Simvastatin affects the expression of ALPL mRNA] CTD PMID:28975700 simvastatin affects expression ISO ALPL (Homo sapiens) 6480464 Simvastatin affects the expression of ALPL mRNA CTD PMID:28975700 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of ALPL mRNA CTD PMID:20417880 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Calcitriol inhibits the reaction [Glucose results in decreased expression of ALPL mRNA]] CTD PMID:33450223 sodium arsenite affects methylation ISO ALPL (Homo sapiens) 6480464 sodium arsenite affects the methylation of ALPL gene CTD PMID:28589171 sodium arsenite decreases expression ISO ALPL (Homo sapiens) 6480464 sodium arsenite results in decreased expression of ALPL mRNA CTD PMID:29301061 sodium chloride increases expression ISO Alpl (Rattus norvegicus) 6480464 Sodium Chloride results in increased expression of ALPL mRNA CTD PMID:37992803 sodium cholate multiple interactions EXP 6480464 [Cholesterol more ... CTD PMID:27394961 sodium fluoride affects expression ISO Alpl (Rattus norvegicus) 6480464 Sodium Fluoride affects the expression of ALPL mRNA CTD PMID:25132241 sodium fluoride increases expression ISO ALPL (Homo sapiens) 6480464 Sodium Fluoride results in increased expression of ALPL protein CTD PMID:30259626 sodium fluoride increases expression ISO Alpl (Rattus norvegicus) 6480464 Sodium Fluoride results in increased expression of ALPL mRNA CTD PMID:24300170 sodium fluoride multiple interactions ISO Alpl (Rattus norvegicus) 6480464 DKK1 protein inhibits the reaction [Sodium Fluoride results in increased expression of ALPL mRNA] CTD PMID:24300170 sodium hypochlorite increases expression ISO ALPL (Homo sapiens) 6480464 Sodium Hypochlorite results in increased expression of ALPL mRNA CTD PMID:22083529 sophoraflavanone B multiple interactions ISO ALPL (Homo sapiens) 6480464 [8-prenylnaringenin binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[8-prenylnaringenin binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 sophoraflavanone B increases expression ISO ALPL (Homo sapiens) 6480464 8-prenylnaringenin results in increased expression of ALPL mRNA CTD PMID:16019205 sophoraflavanone B increases activity ISO ALPL (Homo sapiens) 6480464 8-prenylnaringenin results in increased activity of ALPL protein CTD PMID:16019205 spironolactone multiple interactions ISO ALPL (Homo sapiens) 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 styrene multiple interactions ISO ALPL (Homo sapiens) 6480464 [[Volatile Organic Compounds results in increased abundance of Styrene] which results in increased abundance of mandelic acid] which results in increased expression of ALPL protein CTD PMID:34668566 sucrose multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Sucrose] results in increased expression of ALPL protein and gamma-sitosterol inhibits the reaction [[Dietary Fats co-treated with Sucrose] results in increased expression of ALPL protein] CTD PMID:30461321 sulindac multiple interactions ISO ALPL (Homo sapiens) 6480464 Sulindac promotes the reaction [cobaltous chloride results in decreased expression of ALPL protein] and Sulindac promotes the reaction [Deferoxamine results in decreased expression of ALPL protein] CTD PMID:21882223 syringic acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 syringic acid inhibits the reaction [Valproic Acid results in increased activity of ALPL protein] CTD PMID:35543257 T-2 toxin decreases expression EXP 6480464 T-2 Toxin results in decreased expression of ALPL protein CTD PMID:35289972 tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of ALPL mRNA CTD PMID:25123088 tamoxifen multiple interactions ISO Alpl (Rattus norvegicus) 6480464 zinc chloride inhibits the reaction [Tamoxifen results in increased activity of ALPL protein] CTD PMID:31532279 tamoxifen increases activity ISO Alpl (Rattus norvegicus) 6480464 Tamoxifen results in increased activity of ALPL protein CTD PMID:31532279 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of ALPL mRNA CTD PMID:20937368 telmisartan increases activity ISO Alpl (Rattus norvegicus) 329956421 telmisartan increases enzyme activity of Alpl in serum of rats with periodontal disease RGD telmisartan multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Telmisartan inhibits the reaction [Methotrexate results in increased expression of and results in increased secretion of ALPL protein] CTD PMID:27269004 terbutylazine multiple interactions ISO ALPL (Homo sapiens) 6480464 terbutylazine inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 Tesaglitazar increases expression ISO Alpl (Rattus norvegicus) 6480464 tesaglitazar results in increased expression of ALPL mRNA CTD PMID:21515302 tetrachloroethene increases expression EXP 6480464 Tetrachloroethylene results in increased expression of ALPL mRNA CTD PMID:28973375 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ALPL mRNA CTD PMID:17484886 tetrachloromethane multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Ramipril inhibits the reaction [Carbon Tetrachloride results in increased expression of ALPL protein] CTD PMID:26862777 tetrachloromethane increases expression ISO Alpl (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of ALPL protein CTD PMID:26862777 tetrachloromethane multiple interactions EXP 6480464 alisol B 23-acetate inhibits the reaction [Carbon Tetrachloride results in increased activity of ALPL protein] more ... CTD PMID:18436364 and PMID:37573684 tetrachloromethane increases activity EXP 6480464 Carbon Tetrachloride results in increased activity of ALPL protein CTD PMID:18436364 and PMID:37573684 tetraphene increases expression EXP 6480464 benz(a)anthracene results in increased expression of ALPL mRNA CTD PMID:26377693 thiamethoxam multiple interactions ISO Alpl (Rattus norvegicus) 6480464 [fenugreek seed meal results in increased abundance of Polysaccharides] inhibits the reaction [Thiamethoxam results in decreased activity of ALPL protein] CTD PMID:30621503 thiamethoxam increases activity ISO Alpl (Rattus norvegicus) 6480464 Thiamethoxam results in increased activity of ALPL protein CTD PMID:30621503 thioacetamide decreases expression ISO Alpl (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of ALPL mRNA CTD PMID:19784758 and PMID:34492290 thioacetamide increases expression ISO Alpl (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of ALPL protein CTD PMID:37150287 thioacetamide multiple interactions ISO Alpl (Rattus norvegicus) 6480464 indole-3-carbinol affects the reaction [Thioacetamide results in increased expression of ALPL protein] CTD PMID:37150287 titanium dioxide increases expression ISO ALPL (Homo sapiens) 6480464 titanium dioxide results in increased expression of ALPL mRNA CTD PMID:19464052 titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ALPL mRNA CTD PMID:29950665 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of ALPL mRNA and titanium dioxide results in increased expression of ALPL protein CTD PMID:21259345 more ... tramadol increases expression ISO Alpl (Rattus norvegicus) 6480464 Tramadol results in increased expression of ALPL protein CTD PMID:31618080 tramadol multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Tramadol results in increased expression of ALPL protein] CTD PMID:31618080 tributylstannane multiple interactions EXP 6480464 tributyltin promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of ALPL mRNA] CTD PMID:22749964 tributylstannane decreases expression EXP 6480464 tributyltin results in decreased expression of ALPL mRNA and tributyltin results in decreased expression of ALPL protein CTD PMID:22749964 more ... triflumizole decreases expression EXP 6480464 triflumizol results in decreased expression of ALPL mRNA CTD PMID:23086663 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of ALPL mRNA CTD PMID:19042947 triphenylstannane decreases expression EXP 6480464 triphenyltin results in decreased expression of ALPL protein CTD PMID:25777084 triptonide increases expression EXP 6480464 triptonide results in increased expression of ALPL mRNA CTD PMID:33045310 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of ALPL mRNA CTD PMID:30912803 tunicamycin multiple interactions ISO ALPL (Homo sapiens) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] more ... CTD PMID:10567916 tunicamycin multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] and Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein] CTD PMID:10567916 tunicamycin multiple interactions EXP 6480464 Tosylphenylalanyl Chloromethyl Ketone inhibits the reaction [Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein]] and Tunicamycin inhibits the reaction [Tretinoin results in increased activity of ALPL protein] CTD PMID:10567916 tunicamycin increases degradation ISO ALPL (Homo sapiens) 6480464 Tunicamycin results in increased degradation of ALPL protein CTD PMID:10567916 uranium atom multiple interactions ISO Alpl (Rattus norvegicus) 6480464 GHRL protein inhibits the reaction [Uranium results in decreased secretion of ALPL protein] CTD PMID:29477364 uranium atom decreases secretion ISO Alpl (Rattus norvegicus) 6480464 Uranium results in decreased secretion of ALPL protein CTD PMID:29477364 valproic acid decreases methylation ISO ALPL (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of ALPL gene CTD PMID:29154799 valproic acid increases activity ISO Alpl (Rattus norvegicus) 6480464 Valproic Acid results in increased activity of ALPL protein CTD PMID:35543257 valproic acid multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Silymarin inhibits the reaction [Valproic Acid results in increased activity of ALPL protein] and syringic acid inhibits the reaction [Valproic Acid results in increased activity of ALPL protein] CTD PMID:35543257 valproic acid increases expression ISO ALPL (Homo sapiens) 6480464 Valproic Acid results in increased expression of ALPL mRNA CTD PMID:23179753 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of ALPL mRNA CTD PMID:17292431 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of ALPL mRNA CTD PMID:18930951 vitamin E multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Vitamin E inhibits the reaction [Doxorubicin results in decreased activity of ALPL protein] more ... CTD PMID:30064338 more ... warfarin multiple interactions EXP 6480464 Warfarin inhibits the reaction [BMP2 protein results in increased activity of ALPL protein] more ... CTD PMID:21910061 xanthohumol increases activity ISO ALPL (Homo sapiens) 6480464 xanthohumol results in increased activity of ALPL protein CTD PMID:16019205 xanthohumol increases expression ISO ALPL (Homo sapiens) 6480464 xanthohumol results in increased expression of ALPL mRNA CTD PMID:16019205 zearalenone multiple interactions ISO ALPL (Homo sapiens) 6480464 [Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein and fulvestrant inhibits the reaction [[Zearalenone binds to ESR1 protein] which results in increased activity of ALPL protein] CTD PMID:12650720 zinc atom increases expression ISO Alpl (Rattus norvegicus) 6480464 Zinc results in increased expression of ALPL mRNA CTD PMID:16413754 zinc atom multiple interactions EXP 6480464 [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 zinc atom decreases expression ISO Alpl (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of ALPL mRNA CTD PMID:21893222 zinc dichloride multiple interactions EXP 6480464 [zinc chloride deficiency co-treated with N more ... CTD PMID:19913120 zinc dichloride multiple interactions ISO Alpl (Rattus norvegicus) 6480464 Cadmium inhibits the reaction [zinc chloride results in increased activity of ALPL protein] more ... CTD PMID:26214600 and PMID:31532279 zinc dichloride increases activity ISO Alpl (Rattus norvegicus) 6480464 zinc chloride results in increased activity of ALPL protein CTD PMID:26214600 zinc(0) increases expression ISO Alpl (Rattus norvegicus) 6480464 Zinc results in increased expression of ALPL mRNA CTD PMID:16413754 zinc(0) decreases expression ISO Alpl (Rattus norvegicus) 6480464 Zinc deficiency results in decreased expression of ALPL mRNA CTD PMID:21893222 zinc(0) multiple interactions EXP 6480464 [Zinc binds to calcium silicate] which results in increased expression of ALPL mRNA CTD PMID:23483914 zineb multiple interactions ISO ALPL (Homo sapiens) 6480464 Zineb inhibits the reaction [Aldosterone results in increased expression of ALPL mRNA] CTD PMID:29149346 zoledronic acid decreases activity EXP 6480464 zoledronic acid results in decreased activity of ALPL protein CTD PMID:18496637 zoledronic acid multiple interactions EXP 6480464 TNFRSF11B protein affects the reaction [zoledronic acid results in decreased activity of ALPL protein] CTD PMID:18496637
