Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,3-dinitrobenzene | increases expression | ISO | RGD:619936 | 6480464 | 3-dinitrobenzene results in increased expression of KRT19 mRNA | CTD | PMID:21983209 | 1-naphthyl isothiocyanate | increases expression | EXP | | 6480464 | 1-Naphthylisothiocyanate results in increased expression of KRT19 protein | CTD | PMID:21037076 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of KRT19 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:17942748 PMID:16174780 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:619936 | 6480464 | Ethinyl Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:16174780 PMID:17557909 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:16174780 PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT19 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:733914 | 6480464 | diindolylmethane inhibits the reaction [Estradiol results in increased expression of KRT19 mRNA]; more ... | CTD | PMID:11179685 | 17beta-estradiol | multiple interactions | ISO | RGD:733914 | 6480464 | Estradiol promotes the reaction [ESR2 protein affects the expression of KRT19 mRNA] | CTD | PMID:20404318 | 17beta-estradiol | multiple interactions | ISO | RGD:733914 | 6480464 | ESR1 affects the reaction [Estradiol results in increased expression of KRT19 mRNA]; more ... | CTD | PMID:20160136 | 17beta-estradiol | increases expression | ISO | RGD:733914 | 6480464 | Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:11179685 PMID:20160136 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:15289156 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of KRT19 mRNA | CTD | PMID:17640349 | 17beta-estradiol | affects expression | EXP | | 6480464 | Estradiol affects the expression of KRT19 mRNA | CTD | PMID:15598610 | 17beta-estradiol | affects expression | ISO | RGD:733914 | 6480464 | Estradiol affects the expression of KRT19 mRNA | CTD | PMID:14699072 | 17beta-estradiol | increases expression | ISO | RGD:733914 | 6480464 | Estradiol results in increased expression of KRT19 mRNA | CTD | PMID:11179685 | 17beta-estradiol | multiple interactions | ISO | RGD:733914 | 6480464 | ESR1 protein affects the reaction [Estradiol results in increased expression of KRT19 mRNA]; more ... | CTD | PMID:14699072 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | EXP | | 6480464 | Dihydrotestosterone results in increased expression of KRT19 mRNA | CTD | PMID:17023530 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:733914 | 6480464 | Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of KRT19 mRNA] | CTD | PMID:11179685 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KRT19 mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:619936 | 6480464 | [Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of KRT19 mRNA | CTD | PMID:21602191 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | WNT3A protein inhibits the reaction [[Tetrachlorodibenzodioxin binds to and results in increased activity of AHR protein] which results in decreased expression of KRT19 mRNA] | CTD | PMID:21602191 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KRT19 mRNA | CTD | PMID:17035482 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KRT19 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:733914 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KRT19 mRNA | CTD | PMID:20106945 | 2,3-dimethoxynaphthalene-1,4-dione | increases expression | ISO | RGD:733914 | 6480464 | 2,3-dimethoxy-1,4-naphthoquinone results in increased expression of KRT19 mRNA | CTD | PMID:17547211 | 2-acetamidofluorene | increases expression | ISO | RGD:619936 | 6480464 | 2-Acetylaminofluorene results in increased expression of KRT19 mRNA | CTD | PMID:17187413 | 2-acetamidofluorene | multiple interactions | ISO | RGD:619936 | 6480464 | [Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of KRT19 protein | CTD | PMID:17661067 | 2-acetamidofluorene | increases expression | ISO | RGD:619936 | 6480464 | 2-Acetylaminofluorene results in increased expression of KRT19 protein | CTD | PMID:15133858 | 2-methoxyethanol | increases expression | ISO | RGD:619936 | 6480464 | methyl cellosolve results in increased expression of KRT19 mRNA | CTD | PMID:21061450 | 3,3'-diindolylmethane | multiple interactions | ISO | RGD:733914 | 6480464 | 3,3'-diindolylmethane promotes the reaction [NCOA2 protein binds to KRT19 promoter]; more ... | CTD | PMID:20160136 | 3,3'-diindolylmethane | increases expression | ISO | RGD:733914 | 6480464 | 3,3'-diindolylmethane results in increased expression of KRT19 mRNA | CTD | PMID:20160136 | 7,12-dimethyltetraphene | increases expression | ISO | RGD:619936 | 6480464 | 9,10-Dimethyl-1,2-benzanthracene results in increased expression of KRT19 protein | CTD | PMID:22248470 | 7,12-dimethyltetraphene | multiple interactions | ISO | RGD:619936 | 6480464 | [9,10-Dimethyl-1,2-benzanthracene co-treated with Isoflavones] results in increased expression of KRT19 protein | CTD | PMID:22248470 | 9-cis-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | alitretinoin results in increased expression of KRT19 mRNA | CTD | PMID:17034753 PMID:15982314 | 9-cis-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | alitretinoin results in increased expression of KRT19 protein | CTD | PMID:11214822 PMID:15982314 | 9-cis-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | alitretinoin results in increased expression of KRT19 mRNA | CTD | PMID:15982314 PMID:17034753 | 9-cis-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | alitretinoin results in increased expression of KRT19 protein | CTD | PMID:15982314 PMID:11214822 | afimoxifene | decreases expression | EXP | | 6480464 | 4-hydroxytamoxifen results in decreased expression of KRT19 mRNA | CTD | PMID:17640349 | aflatoxin B1 | decreases expression | EXP | | 6480464 | Aflatoxin B1 results in decreased expression of KRT19 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases expression | ISO | RGD:733914 | 6480464 | Aflatoxin B1 results in increased expression of KRT19 mRNA | CTD | PMID:21641981 | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin metabolite results in increased expression of KRT19 mRNA; more ... | CTD | PMID:15982314 | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 mRNA | CTD | PMID:15982314 more ... | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 mRNA | CTD | PMID:17034753 more ... | all-trans-retinoic acid | decreases expression | ISO | RGD:619936 | 6480464 | Tretinoin results in decreased expression of KRT19 mRNA | CTD | PMID:21274875 | all-trans-retinoic acid | multiple interactions | ISO | RGD:619936 | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Tretinoin results in decreased expression of KRT19 mRNA] | CTD | PMID:21274875 | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 mRNA | CTD | PMID:15982314 more ... | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 protein | CTD | PMID:11214822 PMID:15982314 | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 mRNA | CTD | PMID:17034753 more ... | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 protein | CTD | PMID:15982314 PMID:11214822 | all-trans-retinoic acid | increases expression | ISO | RGD:733914 | 6480464 | Tretinoin results in increased expression of KRT19 mRNA | CTD | PMID:15982314 PMID:17034753 | all-trans-retinol | increases expression | ISO | RGD:733914 | 6480464 | Vitamin A results in increased expression of KRT19 mRNA | CTD | PMID:17034753 | ammonium chloride | affects expression | ISO | RGD:619936 | 6480464 | Ammonium Chloride affects the expression of KRT19 mRNA | CTD | PMID:16483693 | ammonium chloride | decreases expression | ISO | RGD:619936 | 6480464 | Ammonium Chloride results in decreased expression of KRT19 protein | CTD | PMID:16483693 | arsenite(3-) | increases expression | EXP | | 6480464 | arsenite results in increased expression of KRT19 mRNA | CTD | PMID:18991936 | arsenite(3-) | increases expression | ISO | RGD:733914 | 6480464 | arsenite results in increased expression of KRT19 mRNA; more ... | CTD | PMID:22011395 | benzo[a]pyrene | affects expression | ISO | RGD:733914 | 6480464 | Benzo(a)pyrene affects the expression of KRT19 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | increases expression | ISO | RGD:733914 | 6480464 | Benzo(a)pyrene results in increased expression of KRT19 mRNA | CTD | PMID:21632981 PMID:22316170 | benzo[a]pyrene | increases expression | ISO | RGD:733914 | 6480464 | Benzo(a)pyrene results in increased expression of KRT19 mRNA | CTD | PMID:22316170 | benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of KRT19 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | RGD:733914 | 6480464 | Benzo(a)pyrene results in increased expression of KRT19 protein | CTD | PMID:17292933 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | [Benzo(a)pyrene co-treated with XPA gene mutant form co-treated with TRP53 gene mutant form] results in decreased expression of KRT19 mRNA | CTD | PMID:21715664 | beta-carotene | increases expression | ISO | RGD:733914 | 6480464 | beta Carotene results in increased expression of KRT19 mRNA | CTD | PMID:17034753 | beta-hexachlorocyclohexane | increases expression | EXP | | 6480464 | beta-hexachlorocyclohexane results in increased expression of KRT19 mRNA | CTD | PMID:17640349 | bis(2-chloroethyl) sulfide | increases phosphorylation | ISO | RGD:733914 | 6480464 | Mustard Gas results in increased phosphorylation of KRT19 protein | CTD | PMID:19845377 | bisphenol A | affects expression | ISO | RGD:733914 | 6480464 | bisphenol A affects the expression of KRT19 mRNA | CTD | PMID:19490990 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of KRT19; more ... | CTD | PMID:20938992 | cisplatin | decreases expression | ISO | RGD:733914 | 6480464 | Cisplatin results in decreased expression of KRT19 mRNA | CTD | PMID:16061661 | cobalt dichloride | increases expression | ISO | RGD:733914 | 6480464 | cobaltous chloride results in increased expression of KRT19 mRNA | CTD | PMID:19376846 | cobalt dichloride | decreases expression | ISO | RGD:733914 | 6480464 | cobaltous chloride results in decreased expression of KRT19 mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | EXP | | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of KRT19 mRNA | CTD | PMID:15467011 | copper(0) | multiple interactions | EXP | | 6480464 | [ATP7A gene mutant form results in increased abundance of Copper] which results in decreased expression of KRT19 mRNA | CTD | PMID:15467011 | copper(2+) sulfate | increases expression | ISO | RGD:733914 | 6480464 | Copper Sulfate results in increased expression of KRT19 mRNA | CTD | PMID:19549813 | coumarin | decreases expression | ISO | RGD:619936 | 6480464 | coumarin results in decreased expression of KRT19 mRNA | CTD | PMID:18480146 | cyclosporin A | decreases expression | ISO | RGD:733914 | 6480464 | Cyclosporine results in decreased expression of KRT19 mRNA | CTD | PMID:20106945 | cytarabine | decreases expression | ISO | RGD:733914 | 6480464 | Cytarabine results in decreased expression of KRT19 mRNA | CTD | PMID:21198554 | daunorubicin | increases expression | ISO | RGD:619936 | 6480464 | Daunorubicin results in increased expression of KRT19 protein | CTD | PMID:2444108 | diarsenic trioxide | decreases response to substance | ISO | RGD:733914 | 6480464 | KRT19 protein results in decreased susceptibility to arsenic trioxide | CTD | PMID:20707922 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of KRT19 mRNA | CTD | PMID:21266533 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of KRT19 mRNA | CTD | PMID:15289156 PMID:16636312 | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of KRT19 mRNA | CTD | PMID:16636312 PMID:15289156 | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of KRT19 mRNA | CTD | PMID:20880076 | diuron | increases expression | ISO | RGD:619936 | 6480464 | Diuron results in increased expression of KRT19 mRNA | CTD | PMID:21551480 | elemental selenium | increases expression | ISO | RGD:733914 | 6480464 | Selenium results in increased expression of KRT19 mRNA | CTD | PMID:19244175 | emodin | decreases expression | ISO | RGD:733914 | 6480464 | Emodin results in decreased expression of KRT19 mRNA | CTD | PMID:16045814 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of KRT19 gene; more ... | CTD | PMID:20938992 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of KRT19 mRNA | CTD | PMID:15289156 | genistein | increases expression | ISO | RGD:619936 | 6480464 | Genistein results in increased expression of KRT19 mRNA | CTD | PMID:22504913 | genistein | increases expression | ISO | RGD:733914 | 6480464 | Genistein results in increased expression of KRT19 protein | CTD | PMID:20884965 | genistein | multiple interactions | ISO | RGD:733914 | 6480464 | ESR2 promotes the reaction [Genistein results in increased expression of KRT19 protein]; more ... | CTD | PMID:20884965 | indole-3-methanol | affects expression | ISO | RGD:619936 | 6480464 | indole-3-carbinol affects the expression of KRT19 mRNA | CTD | PMID:21396975 | isotretinoin | increases expression | ISO | RGD:733914 | 6480464 | Isotretinoin results in increased expression of KRT19 protein; more ... | CTD | PMID:15982314 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of KRT19; more ... | CTD | PMID:20938992 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:619936 | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of KRT19 mRNA | CTD | PMID:18164116 | N-nitrosodiethylamine | increases expression | ISO | RGD:619936 | 6480464 | Diethylnitrosamine results in increased expression of KRT19 protein | CTD | PMID:20935162 | N-nitrosodiethylamine | multiple interactions | ISO | RGD:619936 | 6480464 | [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT19 protein | CTD | PMID:20935162 | N-nitrosodiethylamine | increases expression | ISO | RGD:619936 | 6480464 | Diethylnitrosamine results in increased expression of KRT19 mRNA | CTD | PMID:19638242 | N-nitrosodimethylamine | increases expression | ISO | RGD:733914 | 6480464 | Dimethylnitrosamine results in increased expression of KRT19 mRNA | CTD | PMID:17547211 | naphthalene | increases expression | EXP | | 6480464 | naphthalene results in increased expression of KRT19 protein | CTD | PMID:19438287 | ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of KRT19 mRNA | CTD | PMID:12763052 | paclitaxel | increases expression | ISO | RGD:619936 | 6480464 | Paclitaxel results in increased expression of KRT19 mRNA | CTD | PMID:18754875 | phenobarbital | multiple interactions | EXP | | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of KRT19 mRNA] | CTD | PMID:19482888 | phenobarbital | multiple interactions | ISO | RGD:619936 | 6480464 | [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of KRT19 protein | CTD | PMID:20935162 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of KRT19 mRNA | CTD | PMID:19482888 | phosgene | affects expression | EXP | | 6480464 | Phosgene affects the expression of KRT19 mRNA | CTD | PMID:16300373 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of KRT19 mRNA | CTD | PMID:17426115 | quercetin | increases expression | ISO | RGD:733914 | 6480464 | Quercetin results in increased expression of KRT19 mRNA | CTD | PMID:21632981 | selenium atom | increases expression | ISO | RGD:733914 | 6480464 | Selenium results in increased expression of KRT19 mRNA | CTD | PMID:19244175 | tamoxifen | affects expression | EXP | | 6480464 | Tamoxifen affects the expression of KRT19 mRNA | CTD | PMID:17555576 | tetrachloromethane | multiple interactions | ISO | RGD:619936 | 6480464 | [Carbon Tetrachloride co-treated with 2-Acetylaminofluorene] results in increased expression of KRT19 protein | CTD | PMID:17661067 | tetrachloromethane | decreases expression | ISO | RGD:619936 | 6480464 | Carbon Tetrachloride results in decreased expression of KRT19 mRNA | CTD | PMID:16770575 | toluene 2,4-diisocyanate | multiple interactions | ISO | RGD:733914 | 6480464 | [Toluene 2,4-Diisocyanate binds to ALB protein] which results in increased expression of KRT19 mRNA | CTD | PMID:15478392 | topotecan | affects response to substance | ISO | RGD:733914 | 6480464 | KRT19 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | ursodeoxycholic acid | multiple interactions | ISO | RGD:619936 | 6480464 | Ursodeoxycholic Acid inhibits the reaction [Tretinoin results in decreased expression of KRT19 mRNA] | CTD | PMID:21274875 | zinc atom | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of KRT19 mRNA | CTD | PMID:20857495 | zinc(0) | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of KRT19 mRNA | CTD | PMID:20857495 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process







