Gene: Mmp14 (matrix metallopeptidase 14 (membrane-inserted))  Mus musculus

Symbol: Mmp14
Name: matrix metallopeptidase 14 (membrane-inserted)
Description: ENCODES a protein that exhibits sequence-specific DNA binding transcription factor activity; integrin binding (ortholog); peptidase activator activity (ortholog); INVOLVED IN branching morphogenesis of an epithelial tube; cell migration; lung development; PARTICIPATES IN hypoxia inducible factor pathway; gonadotropin-releasing hormone signaling pathway; ASSOCIATED WITH abnormal axial skeleton morphology; abnormal basement membrane morphology; abnormal blood vessel morphology; ASSOCIATED WITH Arteriosclerosis; Cardiomyopathy, Dilated; Carotid Stenosis; FOUND IN cytoplasm (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrobenzenesulfonic acid
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI325305; matrix metalloproteinase 14 (membrane-inserted); matrix metalloproteinase-14; Membrane type 1-MMP; membrane-type matrix metalloproteinase 1; membrane-type-1 matrix metalloproteinase; MMP-14; MMP-X1; MT-MMP 1; MT-MMP-1; MT1-MMP; MT1MMP; MTMMP1; sabe; type 1 matrix metalloprotease 14
Orthologs: Homo sapiens : MMP14 (matrix metallopeptidase 14 (membrane-inserted))  HGNC
Rattus norvegicus : Mmp14 (matrix metallopeptidase 14 (membrane-inserted))
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm381454,431,604 - 54,441,258+NCBI
Mouse cM Map1427.79 NCBI
Mouse Celera Assembly1452,223,646 - 52,233,174+NCBI
Mouse Genome Assembly Build 371455,050,441 - 55,060,095+NCBI
Mouse Genome Assembly Build 36.11455,050,456 - 55,060,090+NCBI
Mouse Cytogenetic Map14 C2 NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Mmp14
Entrez Gene
Ensembl Gene
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MGI Report
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RGD Object Information
RGD ID: 734119
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2013-05-14
Status: ACTIVE