Gene: Prl (prolactin)  Mus musculus Symbol: Prl Name: prolactin Description: ENCODES a protein that exhibits prolactin receptor binding (ortholog); INVOLVED IN mammary gland development; positive regulation of cell proliferation; positive regulation of JAK-STAT cascade; PARTICIPATES IN Jak-Stat signaling pathway; ASSOCIATED WITH abnormal branching of the mammary ductal tree; abnormal estrous cycle; abnormal gonadotroph morphology; ASSOCIATED WITH Carotid Artery Diseases (ortholog); Hyperprolactinemia (ortholog); Hypertension, Portal (ortholog); FOUND IN secretory granule; extracellular region (ortholog); INTERACTS WITH (S)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol Type: protein-coding RefSeq Status: VALIDATED Also known as: AV290867; OTTMUSP00000000651; Prl1a1; prolactin Orthologs: Homo sapiens : PRL (prolactin)  HGNC Rattus norvegicus : Prl (prolactin) Latest Assembly: Mouse Genome Assembly Build 37 Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 13 27,057,570 - 27,065,204 + NCBI Mouse cM Map 13 12.25   NCBI Mouse Celera Assembly 13 27,286,739 - 27,294,373 + NCBI Mouse Genome Assembly Build 37 13 27,149,439 - 27,157,073 + NCBI Mouse Genome Assembly Build 36.1 13 27,149,445 - 27,157,051 + NCBI Mouse Cytogenetic Map 13 A3.1   NCBI Model Launch Genome Browser (GBrowse) Annotation    (Toggle Detail/Summary View) Disease Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Carotid Artery Diseases Susceptibility ISS RGD:736187 1642555 protein:decreased expression:serum RGD   Hyperprolactinemia   ISS RGD:3403 1642575 protein:increased expression:serum RGD   Hypertension, Portal   ISS RGD:3403 1642556 protein:decreased expression:plasma RGD   Hypertension, Renovascular   ISS RGD:3403 1642574 protein:increased expression:plasma RGD   Hypoglycemia   ISS RGD:736187 1642557 associated with Hypertension RGD   Insulin Resistance   ISS RGD:736187 1642560 associated with Hyperprolactinemia RGD   Metabolic Syndrome X   ISS RGD:736187 1642558   RGD   Obesity   ISS RGD:736187 1642559   RGD   Prolactinoma   ISS RGD:3403 1642576 DNA, mRNA:mutation, increased expression:pituitary gland RGD   Gene-Chemical Interaction Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) (2,4-dichlorophenoxy)acetic acid decreases secretion ISO RGD:3403 6480464 2,4-Dichlorophenoxyacetic Acid results in decreased secretion of PRL protein CTD PMID:20122984 (S)-amphetamine decreases expression EXP   6480464 Dextroamphetamine results in decreased expression of PRL mRNA CTD PMID:12558987 (S)-amphetamine increases expression ISO RGD:3403 6480464 Dextroamphetamine results in increased expression of PRL mRNA CTD PMID:11440201 (S)-amphetamine decreases expression ISO RGD:3403 6480464 Dextroamphetamine results in decreased expression of PRL mRNA; more ... CTD PMID:11440201 (Z)-chlorprothixene increases secretion ISO RGD:736187 6480464 Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 1-(3-chlorophenyl)piperazine multiple interactions ISO RGD:736187 6480464 Cocaine inhibits the reaction [1-(3-chlorophenyl)piperazine results in increased expression of PRL protein] CTD PMID:16418827 1-(3-chlorophenyl)piperazine increases expression ISO RGD:736187 6480464 1-(3-chlorophenyl)piperazine results in increased expression of PRL protein CTD PMID:9598218 PMID:16418827 1-(3-chlorophenyl)piperazine increases expression ISO RGD:736187 6480464 1-(3-chlorophenyl)piperazine results in increased expression of PRL protein CTD PMID:16418827 PMID:9598218 17alpha-ethynylestradiol multiple interactions ISO RGD:736187 6480464 [Cyproterone Acetate co-treated with Ethinyl Estradiol] results in decreased expression of PRL protein CTD PMID:3157511 17alpha-ethynylestradiol increases expression ISO RGD:3403 6480464 Ethinyl Estradiol analog results in increased expression of PRL protein CTD PMID:3780563 17alpha-ethynylestradiol increases expression ISO RGD:3403 6480464 Ethinyl Estradiol results in increased expression of PRL protein CTD PMID:1968981 17alpha-ethynylestradiol multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRL mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression EXP   6480464 Ethinyl Estradiol results in increased expression of PRL mRNA CTD PMID:17942748 17alpha-ethynylestradiol affects expression EXP   6480464 Ethinyl Estradiol affects the expression of PRL mRNA CTD PMID:17555576 17beta-estradiol multiple interactions EXP   6480464 4-ethylphenol inhibits the reaction [Estradiol results in increased secretion of PRL protein]; more ... CTD PMID:20950447 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Estradiol results in increased expression of and results in increased secretion of PRL protein; more ... CTD PMID:17909072 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Estradiol inhibits the reaction [resveratrol results in decreased expression of PRL protein] CTD PMID:22104698 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:11498938 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:12030773 more ... 17beta-estradiol multiple interactions ISO RGD:3403 6480464 [9,10-Dimethyl-1,2-benzanthracene co-treated with Estradiol] results in increased secretion of PRL protein CTD PMID:3141044 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:12030773 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:10652244 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:11408345 more ... 17beta-estradiol multiple interactions ISO RGD:3403 6480464 [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 protein]; more ... CTD PMID:8674863 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:12030773 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:11498938 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:11408345 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:19479013 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:6743839 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:7585526 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:19479013 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:7306549 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:2446353 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:17174995 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:7306549 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:12804517 more ... 17beta-estradiol multiple interactions ISO RGD:736187 6480464 PRL promoter mutant form affects the reaction [[Progesterone co-treated with Estradiol] results in increased expression of PRL mRNA] CTD PMID:17187171 PMID:17187171 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Estriol promotes the reaction [Estradiol results in increased expression of PRL mRNA]; more ... CTD PMID:7306549 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:17174995 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:17033158 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:7585526 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol analog results in increased expression of PRL protein CTD PMID:3780563 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Estradiol results in increased secretion of PRL protein] CTD PMID:15811834 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:12030773 more ... 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Estradiol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; more ... CTD PMID:12824819 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:12824819 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:6588219 more ... 17beta-estradiol affects splicing ISO RGD:3403 6480464 Estradiol affects the splicing of PRL mRNA CTD PMID:12824819 17beta-estradiol multiple interactions EXP   6480464 [Estradiol co-treated with PRL protein] results in increased expression of ESR1 protein CTD PMID:11786374 17beta-estradiol increases abundance ISO RGD:736187 6480464 PRL protein results in increased abundance of Estradiol CTD PMID:2943108 17beta-estradiol decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Estradiol CTD PMID:12650681 17beta-estradiol increases secretion ISO RGD:736187 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:17054466 17beta-estradiol multiple interactions ISO RGD:736187 6480464 [fulvestrant co-treated with Estradiol] results in increased secretion of PRL protein CTD PMID:15950373 17beta-estradiol multiple interactions ISO RGD:736187 6480464 PRL promoter mutant form affects the reaction [[Progesterone co-treated with Estradiol] results in increased expression of PRL mRNA] CTD PMID:17187171 17beta-estradiol multiple interactions ISO RGD:736187 6480464 Dinoprostone promotes the reaction [[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA] CTD PMID:7506205 17beta-estradiol multiple interactions ISO RGD:736187 6480464 Clomiphene inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]]; more ... CTD PMID:17054466 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:11498938 more ... 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:10652244 more ... 17beta-estradiol multiple interactions ISO RGD:3403 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of PRL mRNA] CTD PMID:21187122 17beta-estradiol increases secretion ISO RGD:3403 6480464 Estradiol results in increased secretion of PRL protein CTD PMID:15811834 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL mRNA CTD PMID:12030773 more ... 17beta-estradiol increases expression ISO RGD:3403 6480464 Estradiol results in increased expression of PRL protein CTD PMID:6588219 more ... 17beta-estradiol increases secretion EXP   6480464 Estradiol results in increased secretion of PRL protein CTD PMID:20950447 17beta-hydroxy-5alpha-androstan-3-one decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Dihydrotestosterone CTD PMID:2943108 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP   6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRL mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:3403 6480464 Tetrachlorodibenzodioxin inhibits the reaction [Estradiol results in increased expression of PRL mRNA] CTD PMID:21187122 2-methoxyethanol increases expression ISO RGD:3403 6480464 methyl cellosolve results in increased expression of PRL mRNA; more ... CTD PMID:21427058 2-methoxyethanol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of PRL protein] CTD PMID:21427058 3',5'-cyclic AMP multiple interactions ISO RGD:3403 6480464 [Atrazine results in increased abundance of Cyclic AMP] which results in increased secretion of PRL protein CTD PMID:23022511 3,3',5-triiodo-L-thyronine decreases expression ISO RGD:3403 6480464 Triiodothyronine results in decreased expression of PRL mRNA; more ... CTD PMID:3734668 3,3',5-triiodo-L-thyronine increases secretion ISO RGD:3403 6480464 Triiodothyronine results in increased secretion of PRL protein CTD PMID:17615682 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:3403 6480464 bisphenol A inhibits the reaction [Triiodothyronine results in increased secretion of PRL protein]; more ... CTD PMID:17615682 4-ethylphenol multiple interactions EXP   6480464 4-ethylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; more ... CTD PMID:20950447 4-ethylphenol increases secretion EXP   6480464 4-ethylphenol results in increased secretion of PRL protein CTD PMID:20950447 4-ethylphenol increases secretion ISO RGD:3403 6480464 4-ethylphenol results in increased secretion of PRL protein CTD PMID:19479013 4-nonylphenol multiple interactions EXP   6480464 4-nonylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; more ... CTD PMID:20950447 4-nonylphenol increases secretion ISO RGD:3403 6480464 4-nonylphenol results in increased secretion of PRL protein CTD PMID:19463694 PMID:17174995 4-nonylphenol increases secretion ISO RGD:3403 6480464 4-nonylphenol results in increased secretion of PRL protein CTD PMID:17174995 PMID:19463694 4-nonylphenol multiple interactions ISO RGD:3403 6480464 fulvestrant inhibits the reaction [4-nonylphenol results in increased secretion of PRL protein]; more ... CTD PMID:19463694 4-nonylphenol increases expression ISO RGD:3403 6480464 4-nonylphenol results in increased expression of PRL mRNA CTD PMID:19463694 4-nonylphenol increases secretion EXP   6480464 4-nonylphenol results in increased secretion of PRL protein CTD PMID:20950447 7,12-dimethyltetraphene increases metabolic processing ISO RGD:3403 6480464 PRL protein results in increased metabolism of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:8674863 7,12-dimethyltetraphene increases secretion ISO RGD:3403 6480464 9,10-Dimethyl-1,2-benzanthracene results in increased secretion of PRL protein CTD PMID:3141044 7,12-dimethyltetraphene multiple interactions ISO RGD:3403 6480464 [9,10-Dimethyl-1,2-benzanthracene co-treated with Estradiol] results in increased secretion of PRL protein CTD PMID:3141044 7,12-dimethyltetraphene multiple interactions ISO RGD:3403 6480464 [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] affects the metabolism of 9,10-Dimethyl-1,2-benzanthracene CTD PMID:8674863 8-bromo-3',5'-cyclic AMP increases secretion ISO RGD:736187 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased secretion of PRL protein CTD PMID:21273127 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:3403 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA CTD PMID:21467749 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:736187 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA CTD PMID:15774544 more ... 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:736187 6480464 Tobacco Smoke Pollution inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA] CTD PMID:20955787 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:736187 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA CTD PMID:17065600 more ... 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:736187 6480464 FOXO1 protein affects the reaction [[Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein] CTD PMID:16709600 8-bromo-3',5'-cyclic AMP increases expression ISO RGD:736187 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA CTD PMID:17065600 PMID:15774544 8-bromo-3',5'-cyclic AMP multiple interactions ISO RGD:736187 6480464 1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA]; more ... CTD PMID:17065600 actinomycin D multiple interactions EXP   6480464 Dactinomycin inhibits the reaction [PRL protein results in increased expression of SLC30A2 mRNA] CTD PMID:19494234 alpha-methyl-L-dopa increases expression ISO RGD:736187 6480464 Methyldopa results in increased expression of PRL protein CTD PMID:1867878 alpha-methyl-L-dopa increases secretion ISO RGD:736187 6480464 Methyldopa results in increased secretion of PRL protein CTD PMID:7265421 aluminium trichloride decreases expression EXP   6480464 aluminum chloride results in decreased expression of PRL protein CTD PMID:15202764 amiodarone decreases expression ISO RGD:3403 6480464 Amiodarone results in decreased expression of PRL mRNA CTD PMID:3427795 ammonia decreases secretion ISO RGD:3403 6480464 Ammonia results in decreased secretion of PRL protein CTD PMID:17119344 ammonia decreases expression ISO RGD:3403 6480464 Ammonia results in decreased expression of PRL protein CTD PMID:17119344 ammonium chloride affects expression ISO RGD:3403 6480464 Ammonium Chloride affects the expression of PRL mRNA CTD PMID:16483693 amoxapine increases expression ISO RGD:736187 6480464 Amoxapine results in increased expression of PRL protein CTD PMID:6363397 apomorphine decreases expression ISO RGD:736187 6480464 Apomorphine results in decreased expression of PRL protein CTD PMID:8889285 aripiprazole multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19653986 more ... aripiprazole decreases expression ISO RGD:736187 6480464 aripiprazole results in decreased expression of PRL protein CTD PMID:19519261 PMID:19230981 aripiprazole multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19906340 more ... aripiprazole increases secretion ISO RGD:3403 6480464 aripiprazole results in increased secretion of PRL protein CTD PMID:8613910 aripiprazole decreases secretion ISO RGD:3403 6480464 aripiprazole results in decreased secretion of PRL protein CTD PMID:8613910 aripiprazole multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19653986 more ... aripiprazole decreases expression ISO RGD:736187 6480464 aripiprazole results in decreased expression of PRL protein CTD PMID:19230981 PMID:19519261 aripiprazole multiple interactions ISO RGD:3403 6480464 aripiprazole inhibits the reaction [talipexole results in decreased secretion of PRL protein]; more ... CTD PMID:8613910 aripiprazole multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [haloperidol decanoate results in increased expression of PRL protein] CTD PMID:17873694 Aroclor 1254 multiple interactions ISO RGD:3403 6480464 Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of PRL protein]; more ... CTD PMID:16298753 Aroclor 1254 multiple interactions ISO RGD:3403 6480464 Chlorodiphenyl (54% Chlorine) promotes the reaction [Triiodothyronine results in increased secretion of PRL protein] CTD PMID:17615682 Aroclor 1254 decreases expression ISO RGD:3403 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PRL protein CTD PMID:16298753 atrazine multiple interactions ISO RGD:3403 6480464 Atrazine inhibits the reaction [estradiol 3-benzoate results in increased secretion of PRL protein] CTD PMID:10696778 atrazine multiple interactions ISO RGD:3403 6480464 [Atrazine results in increased abundance of Cyclic AMP] which results in increased secretion of PRL protein CTD PMID:23022511 atrazine increases expression ISO RGD:3403 6480464 Atrazine results in increased expression of PRL protein CTD PMID:11071396 bis(2-ethylhexyl) phthalate multiple interactions EXP   6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased expression of PRL mRNA CTD PMID:22828881 bisphenol A multiple interactions EXP   6480464 bisphenol A affects the reaction [Estriol results in increased secretion of PRL protein]; more ... CTD PMID:20950447 bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:10652244 more ... bisphenol A multiple interactions ISO RGD:3403 6480464 bisphenol A inhibits the reaction [Triiodothyronine results in increased secretion of PRL protein] CTD PMID:17615682 bisphenol A increases expression EXP   6480464 bisphenol A results in increased expression of PRL protein CTD PMID:12510852 bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:15811834 more ... bisphenol A increases expression ISO RGD:3403 6480464 bisphenol A results in increased expression of PRL mRNA CTD PMID:19463694 PMID:9112368 bisphenol A multiple interactions EXP   6480464 [bisphenol A co-treated with Diethylhexyl Phthalate] results in decreased expression of PRL mRNA CTD PMID:22828881 bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:15811834 more ... bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:19479013 more ... bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:19479013 more ... bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:19463694 more ... bisphenol A multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [bisphenol A results in increased secretion of PRL protein] CTD PMID:15811834 bisphenol A multiple interactions ISO RGD:3403 6480464 fulvestrant inhibits the reaction [bisphenol A results in increased expression of PRL mRNA]; more ... CTD PMID:19463694 bisphenol A increases expression ISO RGD:3403 6480464 bisphenol A results in increased expression of PRL protein CTD PMID:12810577 bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:15811834 more ... bisphenol A increases expression ISO RGD:3403 6480464 bisphenol A results in increased expression of PRL mRNA CTD PMID:19463694 bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:19463694 more ... bisphenol A increases secretion ISO RGD:3403 6480464 bisphenol A results in increased secretion of PRL protein CTD PMID:15811834 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:12161478 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:12161478 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:11685661 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:15046398 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:3776530 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:2887062 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3625096 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:3745407 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:3776530 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:7670571 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:15677882 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:2042694 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:2042694 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; more ... CTD PMID:7670571 bromocriptine multiple interactions ISO RGD:3403 6480464 Ethanol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; more ... CTD PMID:12824819 bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:11685661 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:21427058 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [methyl cellosolve results in increased expression of PRL protein] CTD PMID:21427058 bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [sultopride results in increased secretion of PRL protein] CTD PMID:12106810 bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [estradiol valerate results in increased expression of PRL protein] CTD PMID:6477585 bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:3208992 bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3208992 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL mRNA] CTD PMID:3625096 bromocriptine decreases expression EXP   6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:11786374 bromocriptine multiple interactions ISO RGD:736187 6480464 Bromocriptine inhibits the reaction [Nalorphine results in increased expression of PRL protein] CTD PMID:7106173 bromocriptine decreases secretion ISO RGD:736187 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:3660204 bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:2042694 more ... bromocriptine multiple interactions ISO RGD:736187 6480464 Bromocriptine inhibits the reaction [VIP protein results in increased expression of PRL protein] CTD PMID:6441721 bromocriptine multiple interactions ISO RGD:736187 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:7168914 bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:21427058 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:12824819 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:1874184 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:12742521 more ... bromocriptine decreases expression ISO RGD:736187 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:6986893 more ... bromocriptine multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3625096 more ... bromocriptine decreases expression ISO RGD:3403 6480464 Bromocriptine results in decreased expression of PRL protein CTD PMID:21427058 more ... bromocriptine decreases secretion ISO RGD:3403 6480464 Bromocriptine results in decreased secretion of PRL protein CTD PMID:7670571 more ... buspirone increases secretion ISO RGD:736187 6480464 Buspirone results in increased secretion of PRL protein CTD PMID:18194152 buspirone increases secretion ISO RGD:3403 6480464 Buspirone results in increased secretion of PRL protein CTD PMID:18194152 buspirone multiple interactions ISO RGD:736187 6480464 Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein] CTD PMID:18194152 buspirone multiple interactions ISO RGD:3403 6480464 Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein] CTD PMID:18194152 buspirone increases expression ISO RGD:736187 6480464 Buspirone results in increased expression of PRL protein CTD PMID:19762159 butan-1-ol multiple interactions ISO RGD:736187 6480464 1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA] CTD PMID:17065600 cabergoline decreases expression ISO RGD:736187 6480464 cabergoline results in decreased expression of PRL protein CTD PMID:15377706 PMID:3745407 cabergoline decreases expression ISO RGD:736187 6480464 cabergoline results in decreased expression of PRL protein CTD PMID:3745407 PMID:15377706 cabergoline multiple interactions ISO RGD:3403 6480464 Sulpiride inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; more ... CTD PMID:7670571 cabergoline decreases secretion ISO RGD:3403 6480464 cabergoline results in decreased secretion of PRL protein CTD PMID:7670571 cabergoline decreases secretion ISO RGD:736187 6480464 cabergoline results in decreased secretion of PRL protein CTD PMID:2570719 cadmium atom decreases expression ISO RGD:3403 6480464 Cadmium results in decreased expression of PRL protein CTD PMID:20197452 cadmium atom increases expression ISO RGD:3403 6480464 Cadmium results in increased expression of PRL protein CTD PMID:20455018 cadmium atom multiple interactions ISO RGD:3403 6480464 Lithium inhibits the reaction [Cadmium results in increased expression of PRL protein] CTD PMID:20455018 cadmium dichloride decreases expression ISO RGD:3403 6480464 Cadmium Chloride results in decreased expression of PRL mRNA CTD PMID:19894126 carmoxirole multiple interactions ISO RGD:3403 6480464 carmoxirole inhibits the reaction [sultopride results in increased secretion of PRL protein] CTD PMID:12106810 carmustine decreases expression ISO RGD:736187 6480464 Carmustine results in decreased expression of PRL mRNA CTD PMID:15980968 cetrorelix decreases expression ISO RGD:3403 6480464 cetrorelix results in decreased expression of PRL protein CTD PMID:17638707 chlorpromazine increases expression ISO RGD:736187 6480464 Chlorpromazine results in increased expression of PRL protein CTD PMID:996201 PMID:718334 chlorpromazine increases expression ISO RGD:736187 6480464 Chlorpromazine results in increased expression of PRL protein CTD PMID:718334 PMID:996201 chlorprothixene increases secretion ISO RGD:736187 6480464 Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 cimetidine affects expression ISO RGD:736187 6480464 Cimetidine affects the expression of PRL protein CTD PMID:435711 PMID:9037573 cimetidine affects expression ISO RGD:736187 6480464 Cimetidine affects the expression of PRL protein CTD PMID:9037573 PMID:435711 cisplatin increases expression ISO RGD:736187 6480464 Cisplatin results in increased expression of PRL protein CTD PMID:8312290 citalopram affects secretion ISO RGD:736187 6480464 Citalopram affects the secretion of PRL protein CTD PMID:17000009 citalopram multiple interactions ISO RGD:736187 6480464 SLC6A4 polymorphism inhibits the reaction [Citalopram affects the secretion of PRL protein] CTD PMID:17000009 citalopram increases expression ISO RGD:736187 6480464 Citalopram results in increased expression of PRL protein CTD PMID:19153152 clomiphene multiple interactions ISO RGD:736187 6480464 Clomiphene inhibits the reaction [Estradiol results in increased secretion of PRL protein]; more ... CTD PMID:17054466 clomiphene multiple interactions ISO RGD:736187 6480464 PRL protein inhibits the reaction [Clomiphene results in increased secretion of LHB protein] CTD PMID:3891423 clomipramine increases expression ISO RGD:736187 6480464 Clomipramine results in increased expression of PRL protein CTD PMID:3602989 PMID:19698552 clomipramine increases expression ISO RGD:736187 6480464 Clomipramine results in increased expression of PRL protein CTD PMID:19698552 PMID:3602989 clomipramine multiple interactions ISO RGD:736187 6480464 SLC6A4 polymorphism inhibits the reaction [Clomipramine affects the secretion of PRL protein] CTD PMID:17000009 clomipramine increases secretion ISO RGD:736187 6480464 Clomipramine results in increased secretion of PRL protein CTD PMID:7930386 clomipramine affects secretion ISO RGD:736187 6480464 Clomipramine affects the secretion of PRL protein CTD PMID:17000009 clonidine increases expression ISO RGD:736187 6480464 Clonidine results in increased expression of PRL protein CTD PMID:16401171 clonidine multiple interactions ISO RGD:3403 6480464 Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] CTD PMID:1678730 clonidine (amino form) increases expression ISO RGD:736187 6480464 Clonidine results in increased expression of PRL protein CTD PMID:16401171 clonidine (amino form) multiple interactions ISO RGD:3403 6480464 Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] CTD PMID:1678730 clonidine (imino form) increases expression ISO RGD:736187 6480464 Clonidine results in increased expression of PRL protein CTD PMID:16401171 clonidine (imino form) multiple interactions ISO RGD:3403 6480464 Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein] CTD PMID:1678730 clozapine increases secretion ISO RGD:736187 6480464 Clozapine results in increased secretion of PRL protein CTD PMID:11155212 PMID:15286066 clozapine increases secretion ISO RGD:736187 6480464 Clozapine results in increased secretion of PRL protein CTD PMID:15286066 PMID:11155212 clozapine increases expression ISO RGD:3403 6480464 Clozapine analog results in increased expression of PRL protein CTD PMID:11997696 clozapine multiple interactions ISO RGD:736187 6480464 [Risperidone co-treated with Clozapine] results in increased expression of PRL protein CTD PMID:18562423 clozapine multiple interactions ISO RGD:736187 6480464 [Clozapine co-treated with DRD2 gene polymorphism] results in increased secretion of PRL protein CTD PMID:15286066 cocaine affects expression ISO RGD:736187 6480464 Cocaine affects the expression of PRL protein CTD PMID:14512708 cocaine decreases expression ISO RGD:3403 6480464 Cocaine results in decreased expression of PRL protein CTD PMID:12892653 cocaine increases expression ISO RGD:736187 6480464 Cocaine results in increased expression of PRL protein CTD PMID:15064918 cocaine decreases secretion ISO RGD:736187 6480464 Cocaine results in decreased secretion of PRL protein CTD PMID:17000009 cocaine decreases expression ISO RGD:736187 6480464 Cocaine results in decreased expression of PRL protein CTD PMID:15833589 cocaine affects secretion ISO RGD:736187 6480464 Cocaine affects the secretion of PRL protein CTD PMID:2584360 cocaine multiple interactions ISO RGD:736187 6480464 Cocaine inhibits the reaction [1-(3-chlorophenyl)piperazine results in increased expression of PRL protein] CTD PMID:16418827 cocaine multiple interactions ISO RGD:736187 6480464 Cocaine affects the reaction [Fenfluramine results in increased expression of PRL protein] CTD PMID:10349036 copper atom multiple interactions ISO RGD:3403 6480464 PRL protein promotes the reaction [ATP7A protein results in increased secretion of Copper]; more ... CTD PMID:16741141 copper(0) multiple interactions ISO RGD:3403 6480464 PRL protein promotes the reaction [ATP7A protein results in increased secretion of Copper]; more ... CTD PMID:16741141 cortisol multiple interactions ISO RGD:3403 6480464 [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] affects the metabolism of 9,10-Dimethyl-1,2-benzanthracene; more ... CTD PMID:8674863 coumestrol increases secretion ISO RGD:3403 6480464 Coumestrol results in increased secretion of PRL protein CTD PMID:15811834 more ... coumestrol multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Coumestrol results in increased secretion of PRL protein] CTD PMID:15811834 PMID:17174995 cyanazine increases expression ISO RGD:3403 6480464 cyanazine metabolite results in increased expression of PRL protein; more ... CTD PMID:11071396 cyproheptadine decreases secretion ISO RGD:736187 6480464 Cyproheptadine results in decreased secretion of PRL protein CTD PMID:642945 cyproterone acetate multiple interactions ISO RGD:736187 6480464 [Cyproterone Acetate co-treated with Ethinyl Estradiol] results in decreased expression of PRL protein CTD PMID:3157511 cytarabine increases expression ISO RGD:736187 6480464 Cytarabine results in increased expression of PRL protein CTD PMID:8312290 D-penicillamine multiple interactions ISO RGD:736187 6480464 Danazol inhibits the reaction [Penicillamine results in increased expression of PRL] CTD PMID:4087275 D-penicillamine increases expression ISO RGD:736187 6480464 Penicillamine results in increased expression of PRL CTD PMID:4087275 daidzein increases secretion ISO RGD:3403 6480464 daidzein results in increased secretion of PRL protein CTD PMID:19400946 danazol multiple interactions ISO RGD:736187 6480464 Danazol inhibits the reaction [Penicillamine results in increased expression of PRL] CTD PMID:4087275 DDE increases secretion ISO RGD:3403 6480464 Dichlorodiphenyl Dichloroethylene results in increased secretion of PRL protein CTD PMID:17174995 dehydroepiandrosterone increases secretion ISO RGD:736187 6480464 PRL protein results in increased secretion of Dehydroepiandrosterone CTD PMID:2948424 dehydroepiandrosterone sulfate increases abundance ISO RGD:736187 6480464 PRL protein results in increased abundance of Dehydroepiandrosterone Sulfate CTD PMID:2943108 Delta(9)-tetrahydrocannabinol multiple interactions ISO RGD:3403 6480464 rimonabant inhibits the reaction [Tetrahydrocannabinol results in decreased expression of PRL protein] CTD PMID:9825732 Delta(9)-tetrahydrocannabinol multiple interactions ISO RGD:3403 6480464 Tetrahydrocannabinol affects the reaction [rimonabant results in increased expression of PRL protein] CTD PMID:15099659 Delta(9)-tetrahydrocannabinol decreases expression ISO RGD:3403 6480464 Tetrahydrocannabinol results in decreased expression of PRL protein CTD PMID:9825732 dexamethasone multiple interactions EXP   6480464 [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine co-treated with [Dexamethasone co-treated with INS protein co-treated with PRL protein]] results in decreased expression of BAX protein; more ... CTD PMID:11751460 diazoxide increases expression ISO RGD:3403 6480464 Isoproterenol results in increased expression of PRL CTD PMID:1208595 dieldrin increases secretion ISO RGD:3403 6480464 Dieldrin results in increased secretion of PRL protein CTD PMID:17174995 PMID:15811834 dieldrin increases secretion ISO RGD:3403 6480464 Dieldrin results in increased secretion of PRL protein CTD PMID:15811834 PMID:17174995 dieldrin multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Dieldrin results in increased secretion of PRL protein] CTD PMID:15811834 diethylstilbestrol multiple interactions ISO RGD:736187 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:7168914 diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:11108262 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:1421203 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:12960047 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:12804517 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:6888657 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:15677882 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:12960047 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:12804517 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:1421203 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:7981127 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:12960047 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:1421203 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:7981127 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3208992 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:3208992 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:12960047 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:15677882 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:15677882 more ... diethylstilbestrol increases expression EXP   6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:15470002 PMID:16468032 diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:15811834 PMID:17174995 diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:12960047 more ... diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:17174995 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:15677882 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3208992 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 vasoactive intestinal peptide, 4-chloro-Phe(6)-Leu(17)- inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:15677882 diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Progesterone inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:19082791 diethylstilbestrol increases secretion ISO RGD:3403 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:6888657 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:17174995 PMID:15811834 diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:6888657 more ... diethylstilbestrol increases expression ISO RGD:3403 6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:17005392 more ... diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein] CTD PMID:3208992 diethylstilbestrol multiple interactions ISO RGD:3403 6480464 CQ 32085 inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; more ... CTD PMID:1421203 diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL mRNA] CTD PMID:3625096 diethylstilbestrol multiple interactions ISO RGD:3403 6480464 Bromocriptine inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:3625096 more ... diethylstilbestrol increases expression EXP   6480464 Diethylstilbestrol results in increased expression of PRL protein CTD PMID:16468032 PMID:15470002 diethylstilbestrol increases expression EXP   6480464 Diethylstilbestrol results in increased expression of PRL mRNA CTD PMID:15470002 diethylstilbestrol increases secretion ISO RGD:736187 6480464 Diethylstilbestrol results in increased secretion of PRL protein CTD PMID:7168914 domperidone multiple interactions ISO RGD:736187 6480464 Domperidone inhibits the reaction [Deoxyepinephrine results in decreased expression of PRL protein]; more ... CTD PMID:8532072 domperidone increases expression ISO RGD:3403 6480464 Domperidone results in increased expression of PRL protein CTD PMID:6736848 PMID:1874184 domperidone increases expression ISO RGD:3403 6480464 Domperidone results in increased expression of PRL protein CTD PMID:1874184 PMID:6736848 domperidone increases expression ISO RGD:736187 6480464 Domperidone results in increased expression of PRL protein CTD PMID:1304515 dopamine multiple interactions ISO RGD:736187 6480464 Domperidone inhibits the reaction [Dopamine results in decreased expression of PRL protein] CTD PMID:8532072 dopamine decreases expression ISO RGD:736187 6480464 Dopamine results in decreased expression of PRL protein CTD PMID:8532072 doxapram increases expression ISO RGD:736187 6480464 Doxapram results in increased expression of PRL protein CTD PMID:15741000 doxorubicin increases expression ISO RGD:736187 6480464 Doxorubicin results in increased expression of PRL mRNA; more ... CTD PMID:18681966 duloxetine increases expression ISO RGD:736187 6480464 duloxetine results in increased expression of PRL protein CTD PMID:17606668 endosulfan increases secretion ISO RGD:3403 6480464 Endosulfan results in increased secretion of PRL protein CTD PMID:17174995 more ... endosulfan decreases expression ISO RGD:3403 6480464 Endosulfan results in decreased expression of PRL protein; more ... CTD PMID:20471459 endosulfan multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Endosulfan results in increased secretion of PRL protein] CTD PMID:15811834 PMID:17174995 endosulfan increases secretion ISO RGD:3403 6480464 Endosulfan results in increased secretion of PRL protein CTD PMID:17174995 more ... endosulfan increases secretion ISO RGD:3403 6480464 Endosulfan results in increased secretion of PRL protein CTD PMID:12030773 more ... endosulfan increases secretion ISO RGD:3403 6480464 Endosulfan results in increased secretion of PRL protein CTD PMID:12030773 more ... endosulfan multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Endosulfan results in increased secretion of PRL protein] CTD PMID:17174995 PMID:15811834 endosulfan increases expression ISO RGD:3403 6480464 Endosulfan results in increased expression of PRL mRNA CTD PMID:12030773 estriol increases expression ISO RGD:3403 6480464 Estriol results in increased expression of PRL mRNA CTD PMID:3996322 estriol increases expression ISO RGD:3403 6480464 Estriol results in increased expression of PRL protein CTD PMID:3780563 PMID:7306549 estriol increases secretion EXP   6480464 Estriol results in increased secretion of PRL protein CTD PMID:20950447 estriol multiple interactions EXP   6480464 4-ethylphenol affects the reaction [Estriol results in increased secretion of PRL protein]; more ... CTD PMID:20950447 estriol increases expression ISO RGD:3403 6480464 Estriol results in increased expression of PRL protein CTD PMID:7306549 PMID:3780563 estriol multiple interactions ISO RGD:3403 6480464 Estriol promotes the reaction [Estradiol results in increased expression of PRL mRNA] CTD PMID:7306549 estrone increases expression ISO RGD:3403 6480464 Estrone results in increased expression of PRL protein CTD PMID:3780563 estrone increases secretion EXP   6480464 Estrone results in increased secretion of PRL protein CTD PMID:20950447 estrone multiple interactions EXP   6480464 4-ethylphenol inhibits the reaction [Estrone results in increased secretion of PRL protein]; more ... CTD PMID:20950447 ethanol affects splicing ISO RGD:3403 6480464 Ethanol affects the splicing of PRL mRNA CTD PMID:12824819 ethanol increases expression ISO RGD:3403 6480464 Ethanol results in increased expression of PRL mRNA CTD PMID:12824819 ethanol multiple interactions ISO RGD:3403 6480464 Ethanol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; more ... CTD PMID:12824819 famotidine increases expression ISO RGD:736187 6480464 Famotidine results in increased expression of PRL protein CTD PMID:8104296 fenfluramine multiple interactions ISO RGD:736187 6480464 Cocaine affects the reaction [Fenfluramine results in increased expression of PRL protein] CTD PMID:10349036 fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:10349036 more ... fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9330023 more ... fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9232209 more ... fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9598218 more ... fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9330023 more ... fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9232209 more ... fenfluramine multiple interactions ISO RGD:3403 6480464 Clonidine inhibits the reaction [Fenfluramine results in increased secretion of PRL protein]; more ... CTD PMID:1678730 fenfluramine increases secretion ISO RGD:3403 6480464 Fenfluramine results in increased secretion of PRL protein CTD PMID:1678730 fenfluramine increases expression ISO RGD:736187 6480464 Fenfluramine results in increased expression of PRL protein CTD PMID:9598218 more ... fluoxetine multiple interactions ISO RGD:736187 6480464 [olanzapine co-treated with Fluoxetine] results in increased expression of PRL protein CTD PMID:19896213 fluoxetine increases expression ISO RGD:736187 6480464 Fluoxetine results in increased expression of PRL protein CTD PMID:16848655 PMID:313977 fluoxetine increases expression ISO RGD:3403 6480464 Fluoxetine results in increased expression of PRL protein CTD PMID:9098464 fluoxetine increases expression ISO RGD:736187 6480464 Fluoxetine results in increased expression of PRL protein CTD PMID:313977 PMID:16848655 fluphenazine increases secretion ISO RGD:736187 6480464 Fluphenazine results in increased secretion of PRL protein CTD PMID:9989566 fulvestrant multiple interactions ISO RGD:736187 6480464 [fulvestrant co-treated with Estradiol] results in increased secretion of PRL protein CTD PMID:15950373 fulvestrant multiple interactions ISO RGD:3403 6480464 fulvestrant inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased expression of and results in increased secretion of PRL protein]; more ... CTD PMID:17909072 fulvestrant decreases expression ISO RGD:3403 6480464 fulvestrant results in decreased expression of PRL mRNA; more ... CTD PMID:20419096 fulvestrant multiple interactions ISO RGD:3403 6480464 fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of PRL mRNA]; more ... CTD PMID:19463694 fulvestrant decreases secretion ISO RGD:736187 6480464 fulvestrant results in decreased secretion of PRL protein CTD PMID:15950373 haloperidol affects expression ISO RGD:736187 6480464 Haloperidol affects the expression of PRL protein CTD PMID:1304992 PMID:7214106 haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:11048906 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:10661492 more ... haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:7348089 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:18521575 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:3019639 more ... haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:7348089 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:3883215 more ... haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:15289996 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:3019639 more ... haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:8915564 more ... haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:11071396 more ... haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:16282852 more ... haloperidol affects expression ISO RGD:736187 6480464 Haloperidol affects the expression of PRL protein CTD PMID:7214106 PMID:1304992 haloperidol multiple interactions ISO RGD:3403 6480464 Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein] CTD PMID:3158510 haloperidol increases secretion ISO RGD:3403 6480464 Haloperidol results in increased secretion of PRL protein CTD PMID:8613910 haloperidol multiple interactions ISO RGD:3403 6480464 LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein] CTD PMID:3906589 haloperidol increases expression ISO RGD:3403 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:3883215 more ... haloperidol multiple interactions ISO RGD:3403 6480464 Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; more ... CTD PMID:7670571 haloperidol multiple interactions ISO RGD:3403 6480464 Haloperidol inhibits the reaction [aripiprazole results in decreased secretion of PRL protein]; more ... CTD PMID:8613910 haloperidol increases secretion ISO RGD:736187 6480464 Haloperidol results in increased secretion of PRL protein CTD PMID:9265911 haloperidol increases expression ISO RGD:736187 6480464 Haloperidol results in increased expression of PRL protein CTD PMID:15289996 more ... hexachlorobenzene increases expression ISO RGD:3403 6480464 Hexachlorobenzene results in increased expression of PRL protein CTD PMID:22245120 idazoxan decreases secretion ISO RGD:3403 6480464 Idazoxan results in decreased secretion of PRL protein CTD PMID:1678730 isoprenaline increases expression ISO RGD:3403 6480464 Isoproterenol results in increased expression of PRL CTD PMID:1208595 L-ascorbic acid multiple interactions ISO RGD:3403 6480464 Ascorbic Acid inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of PRL protein] CTD PMID:16298753 labetalol multiple interactions ISO RGD:736187 6480464 carbidopa, levodopa drug combination inhibits the reaction [Labetalol results in increased expression of PRL protein] CTD PMID:7105431 labetalol increases expression ISO RGD:736187 6480464 Labetalol results in increased expression of PRL protein CTD PMID:7105431 lisuride multiple interactions ISO RGD:736187 6480464 Lisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein]; more ... CTD PMID:386688 lisuride decreases secretion ISO RGD:3403 6480464 Lisuride analog results in decreased secretion of PRL protein; more ... CTD PMID:6492995 lithium atom multiple interactions ISO RGD:3403 6480464 Lithium inhibits the reaction [Cadmium results in increased expression of PRL protein] CTD PMID:20455018 losartan multiple interactions ISO RGD:3403 6480464 Losartan inhibits the reaction [AGT protein results in increased secretion of PRL protein] CTD PMID:14722030 maneb multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] affects the expression of PRL mRNA CTD PMID:22563483 manganese(II) chloride decreases expression ISO RGD:3403 6480464 manganese chloride results in decreased expression of PRL protein CTD PMID:18603625 medroxyprogesterone acetate multiple interactions ISO RGD:736187 6480464 Dinoprostone promotes the reaction [[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA] CTD PMID:7506205 medroxyprogesterone acetate multiple interactions ISO RGD:736187 6480464 [Medroxyprogesterone Acetate co-treated with 8-Bromo Cyclic Adenosine Monophosphate] results in increased secretion of PRL protein; more ... CTD PMID:16709600 medroxyprogesterone acetate multiple interactions ISO RGD:736187 6480464 Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of PRL mRNA] CTD PMID:15774544 medroxyprogesterone acetate increases expression ISO RGD:736187 6480464 Medroxyprogesterone Acetate results in increased expression of PRL mRNA CTD PMID:15774544 methadone affects secretion ISO RGD:736187 6480464 Methadone affects the secretion of PRL protein CTD PMID:2554359 methadone increases secretion ISO RGD:736187 6480464 Methadone results in increased secretion of PRL protein CTD PMID:21094671 methadone increases expression ISO RGD:736187 6480464 Methadone results in increased expression of PRL protein CTD PMID:16675813 methamphetamine affects expression ISO RGD:736187 6480464 Methamphetamine affects the expression of PRL protein CTD PMID:21142706 methomyl increases expression ISO RGD:3403 6480464 Methomyl results in increased expression of PRL protein CTD PMID:11516254 methotrexate decreases expression ISO RGD:736187 6480464 Methotrexate results in decreased expression of PRL mRNA CTD PMID:17400583 methoxychlor affects expression ISO RGD:3403 6480464 Methoxychlor affects the expression of PRL protein CTD PMID:2925022 metoclopramide increases secretion ISO RGD:3403 6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:18978642 metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:12056626 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:11561213 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:1304515 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:16584088 more ... metoclopramide increases secretion ISO RGD:736187 6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:8803308 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:7270091 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:14655152 more ... metoclopramide increases secretion ISO RGD:736187 6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:20530986 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:16584088 more ... metoclopramide increases expression EXP   6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:19838586 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:11561213 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:12056626 more ... metoclopramide increases secretion ISO RGD:736187 6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:386688 more ... metoclopramide increases expression EXP   6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:16815880 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:7270091 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:2635674 more ... metoclopramide increases expression EXP   6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:19838586 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:9352036 more ... metoclopramide increases expression ISO RGD:3403 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:16529173 more ... metoclopramide increases expression EXP   6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:17187127 more ... metoclopramide increases secretion EXP   6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:11786374 metoclopramide increases secretion ISO RGD:736187 6480464 Metoclopramide results in increased secretion of PRL protein CTD PMID:8803308 more ... metoclopramide increases expression ISO RGD:736187 6480464 Metoclopramide results in increased expression of PRL protein CTD PMID:11561213 more ... metoclopramide affects expression ISO RGD:736187 6480464 Metoclopramide affects the expression of PRL protein CTD PMID:1304992 metoclopramide multiple interactions ISO RGD:736187 6480464 Metoclopramide results in increased expression of and results in increased secretion of PRL protein CTD PMID:14870917 metoclopramide multiple interactions ISO RGD:736187 6480464 Lisuride inhibits the reaction [Metoclopramide results in increased secretion of PRL protein] CTD PMID:386688 mifepristone multiple interactions ISO RGD:736187 6480464 Mifepristone inhibits the reaction [Medroxyprogesterone Acetate results in increased expression of PRL mRNA] CTD PMID:15774544 mifepristone multiple interactions ISO RGD:3403 6480464 Mifepristone promotes the reaction [estradiol 3-benzoate results in increased secretion of PRL protein] CTD PMID:2159045 mifepristone increases expression ISO RGD:736187 6480464 Mifepristone results in increased expression of PRL mRNA CTD PMID:17584828 mirtazapine increases expression ISO RGD:736187 6480464 mirtazapine results in increased expression of PRL protein CTD PMID:15105766 morphine increases secretion ISO RGD:3403 6480464 Morphine results in increased secretion of PRL protein CTD PMID:7201058 nalbuphine increases expression ISO RGD:736187 6480464 Nalbuphine results in increased expression of PRL protein CTD PMID:17391744 naloxone affects expression ISO RGD:736187 6480464 Naloxone affects the expression of PRL protein CTD PMID:7629406 naloxone decreases expression ISO RGD:3403 6480464 Naloxone results in decreased expression of PRL protein CTD PMID:1794335 nifedipine multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [bisphenol A results in increased secretion of PRL protein]; more ... CTD PMID:15811834 nifedipine multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Diethylstilbestrol results in increased secretion of PRL protein]; more ... CTD PMID:17174995 PMID:15811834 nifedipine multiple interactions ISO RGD:3403 6480464 Nifedipine inhibits the reaction [Coumestrol results in increased secretion of PRL protein]; more ... CTD PMID:15811834 PMID:17174995 nitric oxide multiple interactions ISO RGD:736187 6480464 [PRL co-treated with furylacryloylalanylarginine co-treated with Testosterone] results in increased abundance of Nitric Oxide; more ... CTD PMID:21688280 olanzapine multiple interactions ISO RGD:736187 6480464 [olanzapine co-treated with Fluoxetine] results in increased expression of PRL protein CTD PMID:19896213 olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:10831029 more ... olanzapine increases expression ISO RGD:736187 6480464 olanzapine results in increased expression of PRL protein CTD PMID:18063941 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:11442886 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:10831029 more ... olanzapine increases expression ISO RGD:736187 6480464 olanzapine results in increased expression of PRL protein CTD PMID:9090331 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:10831029 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:10831029 more ... olanzapine increases expression ISO RGD:736187 6480464 olanzapine results in increased expression of PRL protein CTD PMID:11048906 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:15286066 more ... olanzapine increases expression ISO RGD:736187 6480464 olanzapine results in increased expression of PRL protein CTD PMID:11048906 more ... olanzapine increases secretion ISO RGD:736187 6480464 olanzapine results in increased secretion of PRL protein CTD PMID:10831029 more ... olanzapine increases expression ISO RGD:736187 6480464 olanzapine results in increased expression of PRL protein CTD PMID:9376336 more ... omeprazole increases expression ISO RGD:736187 6480464 Omeprazole results in increased expression of PRL protein CTD PMID:20726208 paraquat multiple interactions EXP   6480464 [Paraquat co-treated with Maneb] affects the expression of PRL mRNA CTD PMID:22563483 pentobarbital decreases expression ISO RGD:3403 6480464 Pentobarbital results in decreased expression of PRL protein CTD PMID:17638707 perphenazine increases expression ISO RGD:736187 6480464 Perphenazine results in increased expression of PRL protein CTD PMID:17335319 perphenazine increases expression ISO RGD:3403 6480464 Perphenazine results in increased expression of PRL protein CTD PMID:7262630 PMID:6770916 perphenazine increases expression ISO RGD:3403 6480464 Perphenazine results in increased expression of PRL protein CTD PMID:6770916 PMID:7262630 phenytoin decreases expression ISO RGD:3403 6480464 Phenytoin results in decreased expression of PRL mRNA; more ... CTD PMID:3734668 phorbol 13-acetate 12-myristate increases expression ISO RGD:3403 6480464 Tetradecanoylphorbol Acetate results in increased expression of PRL mRNA CTD PMID:21467749 pimozide increases expression ISO RGD:736187 6480464 Pimozide results in increased expression of PRL protein CTD PMID:8915564 pindolol multiple interactions ISO RGD:736187 6480464 Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein] CTD PMID:18194152 pindolol multiple interactions ISO RGD:3403 6480464 Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein] CTD PMID:18194152 progesterone multiple interactions ISO RGD:736187 6480464 PRL promoter mutant form affects the reaction [[Progesterone co-treated with Estradiol] results in increased expression of PRL mRNA] CTD PMID:17187171 progesterone multiple interactions ISO RGD:3403 6480464 [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] affects the metabolism of 9,10-Dimethyl-1,2-benzanthracene; more ... CTD PMID:8674863 progesterone multiple interactions ISO RGD:736187 6480464 PRL promoter mutant form affects the reaction [[Progesterone co-treated with Estradiol] results in increased expression of PRL mRNA] CTD PMID:17187171 PMID:17187171 progesterone multiple interactions ISO RGD:3403 6480464 Progesterone inhibits the reaction [Diethylstilbestrol results in increased expression of PRL protein] CTD PMID:19082791 progesterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Progesterone CTD PMID:12650681 progesterone increases expression ISO RGD:736187 6480464 Progesterone results in increased expression of PRL mRNA CTD PMID:16403803 propofol increases secretion ISO RGD:736187 6480464 Propofol results in increased secretion of PRL protein CTD PMID:18482853 prostaglandin E2 multiple interactions ISO RGD:736187 6480464 Dinoprostone promotes the reaction [[Estradiol co-treated with Medroxyprogesterone Acetate] results in increased expression of PRL mRNA] CTD PMID:7506205 pyridoxal 5'-phosphate decreases secretion ISO RGD:3403 6480464 Pyridoxal Phosphate results in decreased secretion of PRL protein CTD PMID:16690808 raloxifene multiple interactions ISO RGD:736187 6480464 Raloxifene inhibits the reaction [Estradiol promotes the reaction [GNRH1 protein results in increased secretion of PRL protein]]; more ... CTD PMID:17054466 raloxifene decreases secretion ISO RGD:736187 6480464 Raloxifene results in decreased secretion of PRL protein CTD PMID:15950373 ranitidine increases secretion ISO RGD:736187 6480464 Ranitidine results in increased secretion of PRL protein CTD PMID:7878608 ranitidine affects expression ISO RGD:736187 6480464 Ranitidine affects the expression of PRL protein CTD PMID:9037573 reserpine increases expression ISO RGD:3403 6480464 Reserpine results in increased expression of PRL protein CTD PMID:11071396 resveratrol multiple interactions ISO RGD:3403 6480464 [1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole binds to and results in increased activity of ESR1 protein] inhibits the reaction [resveratrol results in decreased expression of PRL protein]; more ... CTD PMID:22104698 risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19653986 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:11048906 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:10084644 more ... risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19653986 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:20814333 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:15669890 more ... risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:20814333 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:15960571 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:18063941 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:12902212 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:11048906 more ... risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19906340 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:16379509 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:18080171 more ... risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:19906340 more ... risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:18759643 more ... risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:15289996 more ... risperidone multiple interactions ISO RGD:736187 6480464 aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein] CTD PMID:20814333 more ... risperidone multiple interactions ISO RGD:736187 6480464 BDNF gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]; more ... CTD PMID:19997080 risperidone increases secretion ISO RGD:736187 6480464 Risperidone results in increased secretion of PRL protein CTD PMID:15286066 more ... risperidone multiple interactions ISO RGD:736187 6480464 [Risperidone co-treated with Clozapine] results in increased expression of PRL protein CTD PMID:18562423 risperidone increases expression ISO RGD:736187 6480464 Risperidone results in increased expression of PRL protein CTD PMID:18063941 more ... simazine increases expression ISO RGD:3403 6480464 Simazine results in increased expression of PRL protein CTD PMID:11071396 sulpiride increases abundance ISO RGD:736187 6480464 Sulpiride results in increased abundance of PRL protein CTD PMID:2954994 sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:2948424 more ... sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:7243090 more ... sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:2948424 more ... sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:7243090 more ... sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:956353 more ... sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:4001434 more ... sulpiride increases secretion ISO RGD:3403 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:18978642 sulpiride increases expression ISO RGD:3403 6480464 Sulpiride results in increased expression of PRL mRNA; more ... CTD PMID:21427058 sulpiride multiple interactions ISO RGD:3403 6480464 Sulpiride inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; more ... CTD PMID:7670571 sulpiride multiple interactions ISO RGD:736187 6480464 Verapamil inhibits the reaction [Sulpiride results in increased secretion of PRL protein] CTD PMID:7851873 sulpiride multiple interactions ISO RGD:736187 6480464 Triptorelin Pamoate inhibits the reaction [Sulpiride results in increased abundance of PRL protein] CTD PMID:2954994 sulpiride increases secretion ISO RGD:736187 6480464 Sulpiride results in increased secretion of PRL protein CTD PMID:2948424 more ... sulpiride increases expression ISO RGD:736187 6480464 Sulpiride results in increased expression of PRL protein CTD PMID:7106173 tamoxifen affects expression EXP   6480464 Tamoxifen affects the expression of PRL mRNA CTD PMID:17555576 tamoxifen multiple interactions ISO RGD:3403 6480464 Tamoxifen inhibits the reaction [Estradiol results in increased expression of PRL mRNA]; more ... CTD PMID:7306549 tamoxifen increases expression EXP   6480464 Tamoxifen results in increased expression of PRL mRNA CTD PMID:15470002 tamoxifen decreases secretion ISO RGD:736187 6480464 Tamoxifen results in decreased secretion of PRL protein CTD PMID:15950373 temozolomide decreases secretion ISO RGD:3403 6480464 temozolomide results in decreased secretion of PRL protein CTD PMID:20469984 testosterone multiple interactions ISO RGD:736187 6480464 [PRL co-treated with furylacryloylalanylarginine co-treated with Testosterone] results in increased abundance of Nitric Oxide; more ... CTD PMID:21688280 testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:12650681 more ... testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:12650681 more ... testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:8977754 more ... testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:8977754 more ... testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:2943108 more ... testosterone increases expression ISO RGD:736187 6480464 Testosterone results in increased expression of PRL protein CTD PMID:15829128 testosterone increases secretion ISO RGD:736187 6480464 PRL protein results in increased secretion of Testosterone CTD PMID:6643949 testosterone multiple interactions EXP   6480464 PRL7D1 mutant form inhibits the reaction [[PRL co-treated with CGB] results in increased abundance of Testosterone] CTD PMID:21679748 testosterone decreases abundance ISO RGD:736187 6480464 PRL protein results in decreased abundance of Testosterone CTD PMID:9334596 more ... testosterone increases abundance ISO RGD:736187 6480464 PRL protein results in increased abundance of Testosterone CTD PMID:12650681 testosterone affects abundance ISO RGD:736187 6480464 PRL protein affects the abundance of Testosterone CTD PMID:956353 tetrachloromethane increases expression ISO RGD:3403 6480464 Carbon Tetrachloride results in increased expression of PRL mRNA CTD PMID:12832660 tetraphene multiple interactions ISO RGD:3403 6480464 [Estradiol co-treated with Progesterone co-treated with Hydrocortisone co-treated with PRL protein] inhibits the reaction [benz(a)anthracene results in increased expression of CYP1A1 protein]; more ... CTD PMID:8674863 thioridazine increases expression ISO RGD:736187 6480464 Thioridazine results in increased expression of PRL protein CTD PMID:4065553 trans-resveratrol multiple interactions ISO RGD:3403 6480464 [1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole binds to and results in increased activity of ESR1 protein] inhibits the reaction [resveratrol results in decreased expression of PRL protein]; more ... CTD PMID:22104698 trifluoperazine increases expression ISO RGD:736187 6480464 Trifluoperazine results in increased expression of PRL protein CTD PMID:2136057 triptorelin multiple interactions ISO RGD:736187 6480464 Triptorelin Pamoate inhibits the reaction [Sulpiride results in increased abundance of PRL protein] CTD PMID:2954994 triptorelin multiple interactions ISO RGD:3403 6480464 Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein] CTD PMID:3158510 urethane multiple interactions EXP   6480464 [Urethane co-treated with IFNG protein] results in increased expression of PRL mRNA CTD PMID:12810352 venlafaxine increases expression ISO RGD:736187 6480464 venlafaxine results in increased expression of PRL protein CTD PMID:17606668 verapamil multiple interactions ISO RGD:736187 6480464 Verapamil promotes the reaction [TRH protein results in increased secretion of PRL protein]; more ... CTD PMID:7851873 verapamil increases expression ISO RGD:736187 6480464 Verapamil results in increased expression of PRL protein CTD PMID:8977754 PMID:8845563 verapamil increases secretion ISO RGD:736187 6480464 Verapamil results in increased secretion of PRL protein CTD PMID:20595935 verapamil increases expression ISO RGD:736187 6480464 Verapamil results in increased expression of PRL protein CTD PMID:8845563 PMID:8977754 yohimbine increases expression ISO RGD:736187 6480464 Yohimbine results in increased expression of PRL protein CTD PMID:3153710 zinc atom increases expression ISO RGD:3403 6480464 Zinc deficiency results in increased expression of PRL protein CTD PMID:15173390 zinc(0) increases expression ISO RGD:3403 6480464 Zinc deficiency results in increased expression of PRL protein CTD PMID:15173390 zotepine decreases expression ISO RGD:736187 6480464 zotepine results in decreased expression of PRL protein CTD PMID:18063941 Gene Ontology Annotations Biological Process Term Qualifier Evidence With Reference Notes Source Original Reference(s) lactation   IEA UniProtKB-KW:KW-0421 2290270 MGI:MGI:1354194 UniProtKB MGI:MGI:1354194 mammary gland development   IGI MGI:MGI:105088 2290270 MGI:MGI:3799386|PMID:18425773 MGI MGI:MGI:3799386 PMID:18425773 positive regulation of cell proliferation   IGI MGI:MGI:94924 2290270 MGI:MGI:894560|PMID:9247268 MGI MGI:MGI:894560 PMID:9247268 positive regulation of cell proliferation   ISO UniProtKB:P01237 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 positive regulation of epithelial cell proliferation   ISO UniProtKB:P01237 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 positive regulation of JAK-STAT cascade   IGI MGI:MGI:102709 2290270 MGI:MGI:3703676|PMID:12388746 MGI MGI:MGI:3703676 PMID:12388746 positive regulation of JAK-STAT cascade   ISO UniProtKB:P01236 2290270 MGI:MGI:4834177 MGI MGI:MGI:4834177 regulation of JAK-STAT cascade   IDA   2290270 MGI:MGI:2386424|PMID:12147240 MGI MGI:MGI:2386424 PMID:12147240 regulation of ossification   ISO UniProtKB:P01237 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 STAT protein import into nucleus   IDA   2290270 MGI:MGI:2386424|PMID:12147240 MGI MGI:MGI:2386424 PMID:12147240 Cellular Component Term Qualifier Evidence With Reference Notes Source Original Reference(s) extracellular region   ISO UniProtKB:P01237 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 secretory granule   IDA   2290270 MGI:MGI:894561|PMID:9247267 MGI MGI:MGI:894561 PMID:9247267 secretory granule   ISO UniProtKB:P01237 2290270 MGI:MGI:4417868 RGD MGI:MGI:4417868 Molecular Function Term Qualifier Evidence With Reference Notes Source Original Reference(s) hormone activity   TAS   2290270 MGI:MGI:2386424|PMID:12147240 MGI MGI:MGI:2386424 PMID:12147240 prolactin receptor binding   ISO UniProtKB:P01240 2290270 MGI:MGI:2154458 MGI MGI:MGI:2154458 Molecular Pathway Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) Jak-Stat signaling pathway   IEA RGD:11152 6907045   KEGG mmu:04630 External Database Links KEGG Pathway Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Neuroactive ligand-receptor interaction PI3K-Akt signaling pathway Pathway Interaction Database ErbB4 signaling events (PID:200011) Glucocorticoid receptor regulatory network (PID:200091) Signaling events mediated by PTP1B (PID:200042) Validated nuclear estrogen receptor alpha network (PID:200158) Phenotype Annotations Term Qualifier Evidence With Reference Notes Source Original Reference(s) abnormal branching of the mammary ductal tree   IAGP   5509061   MGI PMID:9384572 abnormal estrous cycle   IAGP   5509061   MGI PMID:9384572 abnormal gonadotroph morphology   IAGP   5509061   MGI PMID:12399440 abnormal mammary gland development   IAGP   5509061   MGI PMID:9384572 abnormal mammary gland morphology   IAGP   5509061   MGI PMID:9384572 abnormal pituitary gland morphology   IAGP   5509061   MGI PMID:12399440 abnormal pituitary secretion   IAGP   5509061   MGI PMID:9724019 decreased circulating estradiol level   IAGP   5509061   MGI PMID:12399440 decreased circulating estrogen level   IAGP   5509061   MGI PMID:12399440 decreased circulating luteinizing hormone level   IAGP   5509061   MGI PMID:9724019 decreased circulating prolactin level   IAGP   5509061   MGI PMID:9384572 decreased dopamine level   IAGP   5509061   MGI PMID:9724019 decreased follicle stimulating hormone level   IAGP   5509061   MGI PMID:9724019 decreased lactotroph cell number   IAGP   5509061   MGI PMID:9384572 decreased liver weight   IAGP   5509061   MGI PMID:9724019 decreased luteinizing hormone level   IAGP   5509061   MGI PMID:9724019 decreased prolactin level   IAGP   5509061   MGI PMID:9384572 decreased prolactin level   IAGP   5509061   MGI PMID:9724019 decreased seminal vesicle weight   IAGP   5509061   MGI PMID:9724019 enlarged pituitary gland   IAGP   5509061   MGI PMID:12399440 enlarged pituitary gland   IAGP   5509061   MGI PMID:9724019 failure of embryo implantation   IAGP   5509061   MGI PMID:9384572 female infertility   IAGP   5509061   MGI PMID:9384572 increased pituitary adenoma incidence   IAGP   5509061   MGI PMID:12399440 increased pituitary gland weight   IAGP   5509061   MGI PMID:9724019 pituitary gland hyperplasia   IAGP   5509061   MGI PMID:12399440 prolonged estrous cycle   IAGP   5509061   MGI PMID:9384572 prolonged estrus   IAGP   5509061   MGI PMID:9384572 prolonged proestrus   IAGP   5509061   MGI PMID:9384572 short estrous cycle   IAGP   5509061   MGI PMID:9384572 small prostate gland ventral lobe   IAGP   5509061   MGI PMID:9724019 Disease Annotations Carotid Artery Diseases  (ISS) Hyperprolactinemia  (ISS) Hypertension, Portal  (ISS) Hypertension, Renovascular  (ISS) Hypoglycemia  (ISS) Insulin Resistance  (ISS) Metabolic Syndrome X  (ISS) Obesity  (ISS) Prolactinoma  (ISS) Gene-Chemical Interaction Annotations (2,4-dichlorophenoxy)acetic acid  (ISO) (S)-amphetamine  (EXP,ISO) (Z)-chlorprothixene  (ISO) 1-(3-chlorophenyl)piperazine  (ISO) 17alpha-ethynylestradiol  (EXP,ISO) 17beta-estradiol  (EXP,ISO) 17beta-hydroxy-5alpha-androstan-3-one  (ISO) 2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO) 2-methoxyethanol  (ISO) 3',5'-cyclic AMP  (ISO) 3,3',5-triiodo-L-thyronine  (ISO) 4-ethylphenol  (EXP,ISO) 4-nonylphenol  (EXP,ISO) 7,12-dimethyltetraphene  (ISO) 8-bromo-3',5'-cyclic AMP  (ISO) actinomycin D  (EXP) alpha-methyl-L-dopa  (ISO) aluminium trichloride  (EXP) amiodarone  (ISO) ammonia  (ISO) ammonium chloride  (ISO) amoxapine  (ISO) apomorphine  (ISO) aripiprazole  (ISO) Aroclor 1254  (ISO) atrazine  (ISO) bis(2-ethylhexyl) phthalate  (EXP) bisphenol A  (EXP,ISO) bromocriptine  (EXP,ISO) buspirone  (ISO) butan-1-ol  (ISO) cabergoline  (ISO) cadmium atom  (ISO) cadmium dichloride  (ISO) carmoxirole  (ISO) carmustine  (ISO) cetrorelix  (ISO) chlorpromazine  (ISO) chlorprothixene  (ISO) cimetidine  (ISO) cisplatin  (ISO) citalopram  (ISO) clomiphene  (ISO) clomipramine  (ISO) clonidine  (ISO) clonidine (amino form)  (ISO) clonidine (imino form)  (ISO) clozapine  (ISO) cocaine  (ISO) copper atom  (ISO) copper(0)  (ISO) cortisol  (ISO) coumestrol  (ISO) cyanazine  (ISO) cyproheptadine  (ISO) cyproterone acetate  (ISO) cytarabine  (ISO) D-penicillamine  (ISO) daidzein  (ISO) danazol  (ISO) DDE  (ISO) dehydroepiandrosterone  (ISO) dehydroepiandrosterone sulfate  (ISO) Delta(9)-tetrahydrocannabinol  (ISO) dexamethasone  (EXP) diazoxide  (ISO) dieldrin  (ISO) diethylstilbestrol  (EXP,ISO) domperidone  (ISO) dopamine  (ISO) doxapram  (ISO) doxorubicin  (ISO) duloxetine  (ISO) endosulfan  (ISO) estriol  (EXP,ISO) estrone  (EXP,ISO) ethanol  (ISO) famotidine  (ISO) fenfluramine  (ISO) fluoxetine  (ISO) fluphenazine  (ISO) fulvestrant  (ISO) haloperidol  (ISO) hexachlorobenzene  (ISO) idazoxan  (ISO) isoprenaline  (ISO) L-ascorbic acid  (ISO) labetalol  (ISO) lisuride  (ISO) lithium atom  (ISO) losartan  (ISO) maneb  (EXP) manganese(II) chloride  (ISO) medroxyprogesterone acetate  (ISO) methadone  (ISO) methamphetamine  (ISO) methomyl  (ISO) methotrexate  (ISO) methoxychlor  (ISO) metoclopramide  (EXP,ISO) mifepristone  (ISO) mirtazapine  (ISO) morphine  (ISO) nalbuphine  (ISO) naloxone  (ISO) nifedipine  (ISO) nitric oxide  (ISO) olanzapine  (ISO) omeprazole  (ISO) paraquat  (EXP) pentobarbital  (ISO) perphenazine  (ISO) phenytoin  (ISO) phorbol 13-acetate 12-myristate  (ISO) pimozide  (ISO) pindolol  (ISO) progesterone  (ISO) propofol  (ISO) prostaglandin E2  (ISO) pyridoxal 5'-phosphate  (ISO) raloxifene  (ISO) ranitidine  (ISO) reserpine  (ISO) resveratrol  (ISO) risperidone  (ISO) simazine  (ISO) sulpiride  (ISO) tamoxifen  (EXP,ISO) temozolomide  (ISO) testosterone  (EXP,ISO) tetrachloromethane  (ISO) tetraphene  (ISO) thioridazine  (ISO) trans-resveratrol  (ISO) trifluoperazine  (ISO) triptorelin  (ISO) urethane  (EXP) venlafaxine  (ISO) verapamil  (ISO) yohimbine  (ISO) zinc atom  (ISO) zinc(0)  (ISO) zotepine  (ISO) Gene Ontology Annotations Biological Process lactation  (IEA) mammary gland development  (IGI) positive regulation of cell proliferation  (IGI,ISO) positive regulation of epithelial cell proliferation  (ISO) positive regulation of JAK-STAT cascade  (IGI,ISO) regulation of JAK-STAT cascade  (IDA) regulation of ossification  (ISO) STAT protein import into nucleus  (IDA) Cellular Component extracellular region  (ISO) secretory granule  (IDA,ISO) Molecular Function hormone activity  (TAS) prolactin receptor binding  (ISO) Molecular Pathway Annotations Jak-Stat signaling pathway  (IEA) External Database Links KEGG Pathway Cytokine-cytokine receptor interaction Jak-STAT signaling pathway Neuroactive ligand-receptor interaction PI3K-Akt signaling pathway Pathway Interaction Database ErbB4 signaling events (PID:200011) Glucocorticoid receptor regulatory network (PID:200091) Signaling events mediated by PTP1B (PID:200042) Validated nuclear estrogen receptor alpha network (PID:200158) Phenotype Annotations abnormal branching of the mammary ductal tree  (IAGP) abnormal estrous cycle  (IAGP) abnormal gonadotroph morphology  (IAGP) abnormal mammary gland development  (IAGP) abnormal mammary gland morphology  (IAGP) abnormal pituitary gland morphology  (IAGP) abnormal pituitary secretion  (IAGP) decreased circulating estradiol level  (IAGP) decreased circulating estrogen level  (IAGP) decreased circulating luteinizing hormone level  (IAGP) decreased circulating prolactin level  (IAGP) decreased dopamine level  (IAGP) decreased follicle stimulating hormone level  (IAGP) decreased lactotroph cell number  (IAGP) decreased liver weight  (IAGP) decreased luteinizing hormone level  (IAGP) decreased prolactin level  (IAGP) decreased seminal vesicle weight  (IAGP) enlarged pituitary gland  (IAGP) failure of embryo implantation  (IAGP) female infertility  (IAGP) increased pituitary adenoma incidence  (IAGP) increased pituitary gland weight  (IAGP) pituitary gland hyperplasia  (IAGP) prolonged estrous cycle  (IAGP) prolonged estrus  (IAGP) prolonged proestrus  (IAGP) short estrous cycle  (IAGP) small prostate gland ventral lobe  (IAGP) References - curated 1. Breigeiron MK, etal., Life Sci. 2007 Apr 3;80(17):1627-34. Epub 2007 Jan 27. 2. Hattori N, etal., Endocrinology. 2007 May;148(5):2465-70. Epub 2007 Feb 15. 3. Kawai J, etal., Nature 2001 Feb 8;409(6821):685-90. 4. MGD and Homologene mouse data transfer 5. MGD data from the GO Consortium 6. MGD IEA 7. Muldoon MF, etal., J Clin Endocrinol Metab. 2006 Feb;91(2):718-21. Epub 2005 Nov 22. 8. Muldoon MF, etal., Stroke. 2007 Aug;38(8):2228-33. Epub 2007 Jul 12. 9. Pijl H, etal., Acta Endocrinol (Copenh). 1993 Apr;128(4):319-24. 10. Pipeline to import KEGG annotations from KEGG into RGD Pathway Ontology 11. Radikova Z, etal., J Hum Hypertens. 2006 Jul;20(7):510-6. Epub 2006 Apr 13. 12. RGD automated import pipeline 13. RGD automated import pipeline for gene-chemical interactions 14. Schernthaner G, etal., Diabetologia. 1985 Mar;28(3):138-42. 15. Scorticati C, etal., Neuroimmunomodulation. 2006;13(3):152-9. Epub 2006 Nov 21. 16. Zhang FZ, etal., Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Dec;28(6):822-7. References - uncurated PubMed 10027920   10349636   10364430   10367888   10451227   10465256   10470858   10503715   10588713   10596761   10597135   10607900   10628753   10713693   10900161   10940733   11042159   11076861   11089563   11702241   11721692   11721701   11826766   12130660   12147240   12153463   12388746   12399440   12466851   12477932   12488360   12511652   12554791   12596040   12606280   12651892   12668866   12668875   12707045   12746285   12806178   12810576   12879011   12907761   1358791   14960274   14967897   15459176   15469894   15590989   15601751   15761027   16141072   16141073   16141355   16211235   16267236   1628813   16384867   16484326   16565509   16602821   16625857   16678101   16809445   1682216   16840533   16840539   17015435   17015483   17085971   17255200   17289576   17392792   1744098   17467982   17476555   17548836   17558189   17717072   17728251   17975019   18156207   18253483   18258236   18308464   18425773   18653779   18662396   18775421   18927214   19033670   19093031   19273609   19479826   19494234   19900438   20068010   20484459   20519331   20657157   20699217   20720166   20805495   20807761   20934421   21084383   21084569   21467304   21636786   21677750   21785216   21803118   21914800   21971153   21971318   21989556   22081226   22094470   22193412   22281400   22634956   22945632   22973440   23028142   23070814   23143598   2836164   2963825   2991252   3756168   7744007   7789336   8027530   8391647   8397485   8612966   8614411   8732451   8934515   9119818   9152629   9247267   9247268   9247269   9322957   9384572   9389541   9389542   9620855   9624169   9724019   9822156   9870711 RGD Disease Portals Prl has been annotated in the following RGD Disease Portals. Biological Process Cancer Pathways Cancer Phenotypes Cardiovascular Diseases Cardiovascular Pathways Diabetes Diseases Diabetes Pathways Immune and Inflammatory Pathways Neurological Diseases Neurological Pathways Neurological Phenotypes Obesity Diseases Obesity Pathways Respiratory Pathways Genomics Comparative Map Data Prl   (Mus musculus) Map Chr Position Strand Source Mouse Genome Assembly GRCm38 13 27,057,570 - 27,065,204 + NCBI Mouse cM Map 13 12.25   NCBI Mouse Celera Assembly 13 27,286,739 - 27,294,373 + NCBI Mouse Genome Assembly Build 37 13 27,149,439 - 27,157,073 + NCBI Mouse Genome Assembly Build 36.1 13 27,149,445 - 27,157,051 + NCBI Mouse Cytogenetic Map 13 A3.1   NCBI PRL   (Homo sapiens) Map Chr Position Strand Source Human Alternate Assembly CHM1_1 6 22,209,210 - 22,224,820 - NCBI Human Genome Assembly HuRef 6 22,230,650 - 22,246,259 - NCBI Human Genome Assembly GRCh37 6 22,287,473 - 22,303,082 - NCBI Human Genome Assembly Build 36 6 22,395,459 - 22,405,709 - NCBI Human Cytogenetic Map 6 p22.2-p21.3   NCBI Human Genome Assembly 6 22,395,458 - 22,405,709   NCBI Prl   (Rattus norvegicus) Map Chr Position Strand Source Rat Cytogenetic Map 17 p12   NCBI RGSC Genome Assembly v5.0 17 41,720,752 - 41,730,813 - NCBI RGSC Genome Assembly v3.4 17 44,699,101 - 44,709,162 - NCBI Rat Celera Assembly 17 37,551,071 - 37,561,021 - NCBI Genome Assembly 3.1 17 44,701,945 - 44,712,003 - NCBI Position Markers Prl   Map Chr Position Strand Source Mouse Cytogenetic Map 13 A3.1   UniSTS Prl   Map Chr Position Strand Source Mouse cM Map 13 14.0   UniSTS Mouse Cytogenetic Map 13 A3.1   UniSTS Prl   Map Chr Position Strand Source Mouse Cytogenetic Map 13 A3.1   UniSTS QTLs in Region (Mouse Genome Assembly Build 37) The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer RGD ID Symbol Name LOD P Value Trait Sub Trait Chr Start Stop Species 1301255 Cd4ts6_m CD4 T cell subset 6 (mouse) Not determined 13 85794 34085933 Mouse 4141198 Nilac7_m nicotine induced locomotor activity 7 (mouse) Not determined 13 2721387 36721561 Mouse 1558835 Bdw1_m body weight 1 (mouse) Not determined 13 2721387 36721561 Mouse 1301367 Twq1_m testis weight QTL 1 (mouse) Not determined 13 3523211 37523371 Mouse 1357628 Manln13_m mandible length 13 (mouse) Not determined 13 3587899 37588042 Mouse 1301733 Heal3_m wound healing/regeneration 3 (mouse) Not determined 13 3587899 37588042 Mouse 1558898 Hpi1_m hapatic PMN infiltration 1 (mouse) Not determined 13 4385135 38385302 Mouse 1301984 Pbd2_m peak bone density 2 (mouse) Not determined 13 12327491 46327615 Mouse 1301015 Sysbp2_m systolic blood pressure 2 (mouse) Not determined 13 18064678 52064810 Mouse 1301880 Hypt_m hypertension (mouse) Not determined 13 18064678 52064810 Mouse 1558806 Vacq5_m voluntary alcohol consumption QTL 5 (mouse) Not determined 13 20033374 54033504 Mouse 4142009 Pregq3_m pregnancy QTL 3 (mouse) Not determined 13 20523211 72374518 Mouse 1558844 Lith15_m lithogenic gene 15 (mouse) Not determined 13 21855131 55855299 Mouse 1301361 Idd14_m insulin dependent diabetes susceptibility 14 (mouse) Not determined 13 24008627 58008790 Mouse Sequence Nucleotide Sequences Nucleotide RefSeqs NM_001163530 (Get FASTA) Search GEO for Microarray Profiles   NM_011164 (Get FASTA) Search GEO for Microarray Profiles GenBank Nucleotide AAHY01104921 (Get FASTA) Search GEO for Microarray Profiles   AK017520 (Get FASTA) Search GEO for Microarray Profiles   AK017521 (Get FASTA) Search GEO for Microarray Profiles   AK017547 (Get FASTA) Search GEO for Microarray Profiles   AK017562 (Get FASTA) Search GEO for Microarray Profiles   AK017579 (Get FASTA) Search GEO for Microarray Profiles   AK017584 (Get FASTA) Search GEO for Microarray Profiles   AK077493 (Get FASTA) Search GEO for Microarray Profiles   AK133645 (Get FASTA) Search GEO for Microarray Profiles   AK133736 (Get FASTA) Search GEO for Microarray Profiles   AK133752 (Get FASTA) Search GEO for Microarray Profiles   AK161553 (Get FASTA) Search GEO for Microarray Profiles   AK161557 (Get FASTA) Search GEO for Microarray Profiles   AK161565 (Get FASTA) Search GEO for Microarray Profiles   AK161594 (Get FASTA) Search GEO for Microarray Profiles   AK161619 (Get FASTA) Search GEO for Microarray Profiles   AL591843 (Get FASTA) Search GEO for Microarray Profiles   BC061141 (Get FASTA) Search GEO for Microarray Profiles   CH466561 (Get FASTA) Search GEO for Microarray Profiles   X02892 (Get FASTA) Search GEO for Microarray Profiles   X04418 (Get FASTA) Search GEO for Microarray Profiles Reference Sequences RefSeq Acc Id: NM_011164 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_035294 Peptide Label: isoform 1 precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 13 27,057,570 - 27,065,204 + ENTREZGENE Mouse cM Map 13   + ENTREZGENE Mouse Celera Assembly 13 27,286,739 - 27,294,373 + RGD Mouse Genome Assembly Build 37 13 27,149,439 - 27,157,073 + RGD RefSeq Acc Id: NM_001163530 RefSeq Status: VALIDATED Type: CODING Protein Acc Id: NP_001157002 Peptide Label: isoform 2 precursor Position: Map Chr Position Strand Source Mouse Genome Assembly GRCm38 13 27,057,570 - 27,065,204 + ENTREZGENE Mouse cM Map 13   + ENTREZGENE Mouse Celera Assembly 13 27,286,739 - 27,294,373 + RGD Mouse Genome Assembly Build 37 13 27,149,439 - 27,157,073 + RGD Protein Sequences Protein RefSeqs NP_001157002 (Get FASTA)   NP_035294 (Get FASTA) GenBank Protein AAH61141 (Get FASTA)   BAB30786 (Get FASTA)   BAB30787 (Get FASTA)   BAB30799 (Get FASTA)   BAB30806 (Get FASTA)   BAB30816 (Get FASTA)   BAB30821 (Get FASTA)   BAC36829 (Get FASTA)   BAE21763 (Get FASTA)   BAE21811 (Get FASTA)   BAE21822 (Get FASTA)   BAE36459 (Get FASTA)   BAE36462 (Get FASTA)   BAE36467 (Get FASTA)   BAE36481 (Get FASTA)   BAE36497 (Get FASTA)   CAA26651 (Get FASTA)   CAA28018 (Get FASTA)   EDL32452 (Get FASTA)   EDL32453 (Get FASTA)   P06879 (Get FASTA) Additional Information External Database Links Database Acc Id Source(s) Ensembl Genes ENSMUSG00000021342 ENTREZGENE Ensembl Protein ENSMUSP00000018061 ENTREZGENE   ENSMUSP00000105998 ENTREZGENE Ensembl Transcript ENSMUST00000018061 ENTREZGENE   ENSMUST00000110369 ENTREZGENE Entrez Gene 19109 ENTREZGENE Gene3D-CATH 4_helix_cytokine_core UniProtKB/Swiss-Prot Germonline ENSMUSG00000021342 HomoloGene Group ID 732 ENTREZGENE InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot   4_helix_cytokine_core UniProtKB/Swiss-Prot   Somatotropin UniProtKB/Swiss-Prot   Somatotropin_CS UniProtKB/Swiss-Prot IPI IPI00315133 UniProtKB/Swiss-Prot   IPI00944042 UniProtKB/TrEMBL KEGG Report mmu:19109 ENTREZGENE, UniProtKB/TrEMBL MGD MGI:97762 ENTREZGENE PANTHER Somatotropin UniProtKB/Swiss-Prot Pfam Hormone_1 UniProtKB/Swiss-Prot PRINTS SOMATOTROPIN UniProtKB/Swiss-Prot PROSITE SOMATOTROPIN_1; FALSE_NEG UniProtKB/Swiss-Prot   SOMATOTROPIN_2 UniProtKB/Swiss-Prot Superfamily-SCOP 4_helix_cytokine UniProtKB/Swiss-Prot UniGene Mm.1270 ENTREZGENE UniProt PRL_MOUSE UniProtKB/Swiss-Prot   Q3TT66_MOUSE UniProtKB/TrEMBL   Q9CPQ0_MOUSE UniProtKB/TrEMBL   Q9CPQ2_MOUSE UniProtKB/TrEMBL   Q9CYL2_MOUSE UniProtKB/TrEMBL   Q9CYL8_MOUSE UniProtKB/TrEMBL

More on Prl Entrez Gene Ensembl Gene Genome Browser MGI Report NCBI Map Viewer Vista Vista + UCSC RGD Object Information RGD ID: 11152 Created: 2000-05-25 Species: Mus musculus Last Modified: 2013-04-30 Status: ACTIVE