Sprr2f (small proline-rich protein 2F) - Rat Genome Database

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Gene: Sprr2f (small proline-rich protein 2F) Mus musculus
Analyze
Symbol: Sprr2f
Name: small proline-rich protein 2F
RGD ID: 1614421
MGI Page MGI
Description: Acts upstream of or within response to estradiol. Located in cytoplasm and nucleus. Is expressed in ureteric trunk.
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Human
Rat
Bonobo
Alliance Genes
More Info more info ...
Related Pseudogenes: Sprr2c-ps  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39392,272,494 - 92,273,754 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl392,272,494 - 92,273,749 (+)EnsemblGRCm39 Ensembl
GRCm38392,365,187 - 92,366,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl392,365,187 - 92,366,442 (+)EnsemblGRCm38mm10GRCm38
MGSCv37392,169,109 - 92,170,364 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36392,450,590 - 92,451,845 (+)NCBIMGSCv36mm8
Celera394,716,195 - 94,717,450 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map340.14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8325635   PMID:9888996   PMID:12477932   PMID:12584609   PMID:15232223   PMID:15574822   PMID:16602821   PMID:19301398   PMID:20142330   PMID:20930145   PMID:21677750   PMID:21873635  
PMID:23906066   PMID:26644517   PMID:28705898   PMID:33017192  


Genomics

Comparative Map Data
Sprr2f
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39392,272,494 - 92,273,754 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl392,272,494 - 92,273,749 (+)EnsemblGRCm39 Ensembl
GRCm38392,365,187 - 92,366,442 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl392,365,187 - 92,366,442 (+)EnsemblGRCm38mm10GRCm38
MGSCv37392,169,109 - 92,170,364 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36392,450,590 - 92,451,845 (+)NCBIMGSCv36mm8
Celera394,716,195 - 94,717,450 (-)NCBICelera
Cytogenetic Map3F1NCBI
cM Map340.14NCBI
SPRR2F
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381153,112,121 - 153,119,468 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1153,112,121 - 153,113,516 (-)EnsemblGRCh38hg38GRCh38
GRCh371153,084,597 - 153,091,944 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361151,351,236 - 151,352,613 (-)NCBINCBI36Build 36hg18NCBI36
Celera1126,155,383 - 126,156,760 (-)NCBICelera
Cytogenetic Map1q21.3NCBI
HuRef1124,447,709 - 124,449,086 (-)NCBIHuRef
CHM1_11154,480,487 - 154,481,864 (-)NCBICHM1_1
T2T-CHM13v2.01152,248,934 - 152,256,280 (-)NCBIT2T-CHM13v2.0
Sprr2f
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82180,685,587 - 180,685,817 (+)NCBIGRCr8
mRatBN7.22177,989,974 - 177,990,204 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2177,989,974 - 177,990,204 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.02192,604,978 - 192,605,208 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02212,264,977 - 212,265,207 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2172,268,174 - 172,268,404 (-)NCBICelera
Cytogenetic Map2q34NCBI
LOC100968601
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2196,734,176 - 96,734,561 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,469,924 - 96,470,309 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01128,454,540 - 128,454,965 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11132,082,403 - 132,083,794 (-)NCBIpanpan1.1PanPan1.1panPan2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:99
Count of miRNA genes:96
Interacting mature miRNAs:97
Transcripts:ENSMUST00000050397
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7586174102690034Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884380Skwq1_mskull length QTL 1, 5 week (mouse)343954435101607316Mouse
26884378Skwq6_mskull length QTL 6, 10 week (mouse)351907421102307316Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
11039519Ltpr3_mLeishmania tropica response 3 (mouse)356704102100464137Mouse
12880419V125Dq4_mvitamin D active form serum level QTL 4 (mouse)35890730792907307Mouse
4141294Bmd24_mbone mineral density 24 (mouse)Not determined36174006195740241Mouse
1301971Cia5_mcollagen induced arthritis QTL 5 (mouse)Not determined366046658100046795Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
11251721Ewc3_methanol withdrawal and consumption 3 (mouse)369568554103568554Mouse
1301791Char4_mP. chabaudi malaria resistance QTL 4 (mouse)Not determined369625509100655290Mouse
1301422Sle11_msystematic lupus erythematosus susceptibility 11 (mouse)Not determined370208904104209042Mouse
11049572Lmr11c_mleishmaniasis resistance 11c (mouse)372139967106140094Mouse
1300982Lmr11_mleishmaniasis resistance 11 (mouse)Not determined372139967106140094Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1301398Rapop3_mradiation-induced apoptosis 3 (mouse)Not determined390511217100464137Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse

Markers in Region
BB284336  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38392,366,207 - 92,366,342UniSTSGRCm38
MGSCv37392,170,129 - 92,170,264UniSTSGRCm37
Celera394,716,295 - 94,716,430UniSTS
Cytogenetic Map3F1UniSTS
cM Map345.2UniSTS
Whitehead/MRC_RH31021.48UniSTS
UniSTS:489168  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38392,365,191 - 92,366,332UniSTSGRCm38
MGSCv37392,169,113 - 92,170,254UniSTSGRCm37
Celera394,716,305 - 94,717,446UniSTS
Cytogenetic Map3F1UniSTS
cM Map345.2UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000050397   ⟹   ENSMUSP00000050902
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl392,272,494 - 92,273,749 (+)Ensembl
GRCm38.p6 Ensembl392,365,187 - 92,366,442 (+)Ensembl
RefSeq Acc Id: NM_011472   ⟹   NP_035602
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39392,272,494 - 92,273,754 (+)NCBI
GRCm38392,365,187 - 92,366,442 (+)ENTREZGENE
MGSCv37392,169,109 - 92,170,364 (+)RGD
Celera394,716,195 - 94,717,450 (-)RGD
cM Map3 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_035602   ⟸   NM_011472
- UniProtKB: O70557 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000050902   ⟸   ENSMUST00000050397

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70557-F1-model_v2 AlphaFold O70557 1-76 view protein structure

Promoters
RGD ID:6881394
Promoter ID:EPDNEW_M4148
Type:multiple initiation site
Name:Sprr2f_1
Description:Mus musculus small proline-rich protein 2F , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38392,365,187 - 92,365,247EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1330349 AgrOrtholog
Ensembl Genes ENSMUSG00000050635 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000050397 ENTREZGENE
  ENSMUST00000050397.2 UniProtKB/Swiss-Prot
InterPro SPRR2 UniProtKB/Swiss-Prot
KEGG Report mmu:20760 UniProtKB/Swiss-Prot
MGD MGI:1330349 ENTREZGENE
NCBI Gene 20760 ENTREZGENE
Pfam SPRR2 UniProtKB/Swiss-Prot
PhenoGen Sprr2f PhenoGen
PRINTS PRORICH UniProtKB/Swiss-Prot
UniProt O70557 ENTREZGENE
  Q0P529_MOUSE UniProtKB/TrEMBL
  SPR2F_MOUSE UniProtKB/Swiss-Prot