Hpgd (hydroxyprostaglandin dehydrogenase 15 (NAD)) - Rat Genome Database

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Gene: Hpgd (hydroxyprostaglandin dehydrogenase 15 (NAD)) Mus musculus
Analyze
Symbol: Hpgd
Name: hydroxyprostaglandin dehydrogenase 15 (NAD)
RGD ID: 736887
MGI Page MGI
Description: Enables 15-hydroxyprostaglandin dehydrogenase (NAD+) activity. Involved in ductus arteriosus closure. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; choroid plexus; genitourinary system; humerus cartilage condensation; and nose. Human ortholog(s) of this gene implicated in colon carcinoma and primary hypertrophic osteoarthropathy. Orthologous to human HPGD (15-hydroxyprostaglandin dehydrogenase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 15-hydroxyprostaglandin dehydrogenase; 15-hydroxyprostaglandin dehydrogenase [NAD(+)]; 15-hydroxyprostaglandin dehydrogenase [NAD+]; 15-PGD; 15-PGDH; AV026552; eicosanoid/docosanoid dehydrogenase; MGC14001; PGDH; prostaglandin dehydrogenase 1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39856,747,587 - 56,774,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl856,747,620 - 56,774,078 (+)EnsemblGRCm39 Ensembl
GRCm38856,294,552 - 56,321,046 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl856,294,585 - 56,321,043 (+)EnsemblGRCm38mm10GRCm38
MGSCv37858,773,349 - 58,799,843 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36859,186,738 - 59,212,816 (+)NCBIMGSCv36mm8
Celera858,951,090 - 58,977,585 (+)NCBICelera
Cytogenetic Map8B2NCBI
cM Map829.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,1-dichloroethene  (EXP)
1,2-dimethylhydrazine  (EXP)
15-dehydro-prostaglandin E2  (EXP)
16,16-dimethylprostaglandin E2  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-dichloroaniline  (ISO)
3-methylcholanthrene  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-tert-Octylphenol  (ISO)
5-azacytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
andrographolide  (EXP)
aristolochic acid A  (ISO)
aristolochic acids  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
belinostat  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (EXP,ISO)
betamethasone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
buta-1,3-diene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (EXP)
celecoxib  (ISO)
chlorpyrifos  (EXP)
choline  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (ISO)
cobalt atom  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP)
cyclosporin A  (EXP,ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
Echimidine  (ISO)
entinostat  (ISO)
fenoprofen  (ISO)
fenvalerate  (ISO)
flurbiprofen  (ISO)
folic acid  (EXP)
furan  (ISO)
geldanamycin  (ISO)
gentamycin  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
inulin  (EXP)
isoflavones  (ISO)
ketamine  (ISO)
ketoprofen  (ISO)
L-methionine  (EXP)
Lasiocarpine  (ISO)
lead(0)  (ISO)
lidocaine  (ISO)
mefenamic acid  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
methylseleninic acid  (EXP)
mifepristone  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nevirapine  (ISO)
nickel sulfate  (ISO)
Niflumic acid  (ISO)
oxidopamine  (ISO)
ozone  (EXP)
p-chloromercuribenzoic acid  (ISO)
p-tert-Amylphenol  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
pioglitazone  (ISO)
pirinixic acid  (EXP,ISO)
potassium bromate  (EXP)
potassium dichromate  (EXP)
prednisolone  (ISO)
prostaglandin E2  (EXP,ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (EXP)
rofecoxib  (ISO)
SB 431542  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenate  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (EXP)
sulforaphane  (ISO)
sulindac sulfone  (ISO)
tamibarotene  (ISO)
testosterone  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP)
tetracycline  (EXP)
titanium dioxide  (EXP)
tremolite asbestos  (EXP)
triamcinolone  (ISO)
tributylstannane  (EXP)
trichostatin A  (ISO)
valproic acid  (ISO)
vancomycin  (EXP)
vinclozolin  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Loss of 15-hydroxyprostaglandin dehydrogenase indicates a tumor suppressor role in pituitary adenomas. Bai JW, etal., Oncol Rep. 2012 Aug;28(2):714-20. doi: 10.3892/or.2012.1806. Epub 2012 May 9.
2. Altered expression of 15-hydroxyprostaglandin dehydrogenase in tumor-infiltrated CD11b myeloid cells: a mechanism for immune evasion in cancer. Eruslanov E, etal., J Immunol. 2009 Jun 15;182(12):7548-57.
3. Prostaglandin E2 alterations during sepsis are partially mediated by endotoxin-induced inhibition of prostaglandin 15-hydroxydehydrogenase. Hahn EL, etal., J Trauma. 1998 May;44(5):777-81; discussion 781-2.
4. Expression of genes controlling transport and catabolism of prostaglandin E2 in lipopolysaccharide fever. Ivanov AI, etal., Am J Physiol Regul Integr Comp Physiol. 2003 Mar;284(3):R698-706. Epub 2002 Oct 24.
5. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
6. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
7. MGDs mouse GO annotations MGD data from the GO Consortium
8. MGD IEA MGD IEA
9. 15-PGDH inhibitors: the antiulcer effects of carbenoxolone, pioglitazone and verapamil in indomethacin induced peptic ulcer rats. Moustafa YM, etal., Eur Rev Med Pharmacol Sci. 2013;17(15):2000-9.
10. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
11. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
12. Levels of NAD(+)-dependent 15-hydroxyprostaglandin dehydrogenase are reduced in inflammatory bowel disease: evidence for involvement of TNF-alpha. Otani T, etal., Am J Physiol Gastrointest Liver Physiol. 2006 Feb;290(2):G361-8. Epub 2005 Sep 29.
13. 15-Hydroxyprostaglandin dehydrogenase suppresses K-RasV12-dependent tumor formation in Nu/Nu mice. Pham H, etal., Mol Carcinog. 2008 Jun;47(6):466-77.
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. 15-PGDH/15-KETE plays a role in hypoxia-induced pulmonary vascular remodeling through ERK1/2-dependent PAR-2 pathway. Wei L, etal., Cell Signal. 2014 Jul;26(7):1476-88. doi: 10.1016/j.cellsig.2014.03.008. Epub 2014 Mar 18.
Additional References at PubMed
PMID:8950170   PMID:9207200   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11422365   PMID:11821873   PMID:12477932   PMID:14681479   PMID:15489334   PMID:15542609   PMID:16113047  
PMID:16141072   PMID:16141073   PMID:16829211   PMID:16880406   PMID:16910173   PMID:17449869   PMID:17872381   PMID:18057186   PMID:18287559   PMID:18509311   PMID:19470469   PMID:20448048  
PMID:20954077   PMID:21267068   PMID:21308776   PMID:21334450   PMID:21386911   PMID:21653731   PMID:21873635   PMID:22843771   PMID:22967998   PMID:23954207   PMID:25503930   PMID:26068857  
PMID:27140190   PMID:28423012   PMID:28716915   PMID:30250298   PMID:31027998   PMID:31772225   PMID:32408168   PMID:32422251   PMID:32554809   PMID:34389796   PMID:35449600   PMID:35587945  
PMID:35831953   PMID:36045676   PMID:37140231   PMID:37934242  


Genomics

Comparative Map Data
Hpgd
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39856,747,587 - 56,774,081 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl856,747,620 - 56,774,078 (+)EnsemblGRCm39 Ensembl
GRCm38856,294,552 - 56,321,046 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl856,294,585 - 56,321,043 (+)EnsemblGRCm38mm10GRCm38
MGSCv37858,773,349 - 58,799,843 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36859,186,738 - 59,212,816 (+)NCBIMGSCv36mm8
Celera858,951,090 - 58,977,585 (+)NCBICelera
Cytogenetic Map8B2NCBI
cM Map829.7NCBI
HPGD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384174,490,175 - 174,522,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4174,490,175 - 174,523,154 (-)EnsemblGRCh38hg38GRCh38
GRCh374175,411,326 - 175,444,044 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364175,647,955 - 175,680,186 (-)NCBINCBI36Build 36hg18NCBI36
Build 344175,786,110 - 175,818,341NCBI
Celera4172,740,096 - 172,772,812 (-)NCBICelera
Cytogenetic Map4q34.1NCBI
HuRef4171,160,430 - 171,193,154 (-)NCBIHuRef
CHM1_14175,387,688 - 175,420,506 (-)NCBICHM1_1
T2T-CHM13v2.04177,829,876 - 177,862,596 (-)NCBIT2T-CHM13v2.0
Hpgd
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81638,996,876 - 39,034,831 (-)NCBIGRCr8
mRatBN7.21633,986,265 - 34,024,228 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1633,986,266 - 34,024,228 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1637,595,125 - 37,634,909 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01641,006,491 - 41,046,289 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01637,247,961 - 37,285,984 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01637,457,134 - 37,495,758 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1637,457,135 - 37,495,758 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01637,259,044 - 37,296,863 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41637,419,901 - 37,457,896 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11637,419,976 - 37,457,971 (-)NCBI
Celera1633,917,230 - 33,953,504 (-)NCBICelera
Cytogenetic Map16p11NCBI
Hpgd
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540332,569,841 - 32,613,763 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540332,569,841 - 32,614,860 (+)NCBIChiLan1.0ChiLan1.0
HPGD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23172,249,784 - 172,284,553 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14172,630,139 - 172,663,028 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04166,716,386 - 166,749,225 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14178,950,152 - 178,982,910 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4178,949,137 - 178,982,910 (-)Ensemblpanpan1.1panPan2
HPGD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12524,964,908 - 24,993,276 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2524,964,908 - 24,993,297 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2525,617,669 - 25,646,014 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02525,128,311 - 25,156,688 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2525,126,217 - 25,157,016 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12525,076,268 - 25,104,599 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02524,965,511 - 24,993,846 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02525,117,290 - 25,145,635 (-)NCBIUU_Cfam_GSD_1.0
Hpgd
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494325,138,011 - 25,164,513 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365165,550,203 - 5,578,832 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365165,551,192 - 5,578,796 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HPGD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1415,718,678 - 15,760,767 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11415,718,261 - 15,773,534 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21416,909,010 - 16,921,261 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HPGD
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17120,589,646 - 120,620,864 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7120,588,462 - 120,621,016 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037100,655,992 - 100,687,031 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hpgd
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247696,101,474 - 6,139,793 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247696,101,482 - 6,139,465 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hpgd
1142 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:239
Count of miRNA genes:183
Interacting mature miRNAs:210
Transcripts:ENSMUST00000034026
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81477316071498244Mouse
10043974Obq30_mobesity QTL 30 (mouse)Not determined82658332260583322Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83250657271740637Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3250657271740637Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3250657271740637Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3250657271740637Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832506572117965439Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83429039768290537Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined835109930115563747Mouse
11041902Lmr10a_mleishmaniasis resistance 10a (mouse)83532109757797633Mouse
11049578Lmr10c_mleishmaniasis resistance 10c (mouse)83532109757797633Mouse
11049577Lmr10b_mleishmaniasis resistance 10b (mouse)83532109757797633Mouse
1301139Lmr10_mleishmaniasis resistance 10 (mouse)Not determined83532109757797633Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83663015493455280Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837867154110326632Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)84016229795416226Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84474791478748059Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84809006482090180Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84809006482090180Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84819016882190288Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84924559183245673Mouse
14746987Manh64_mmandible shape 64 (mouse)85050595884505958Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85050595884505958Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85233484386334843Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85474046188740637Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85515925889159407Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85629887290298872Mouse

Markers in Region
AV026552  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38856,320,748 - 56,320,870UniSTSGRCm38
MGSCv37858,799,545 - 58,799,667UniSTSGRCm37
Celera858,977,287 - 58,977,409UniSTS
Cytogenetic Map8B3.2UniSTS
Whitehead/MRC_RH8662.64UniSTS
Hpgd  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38856,318,995 - 56,319,075UniSTSGRCm38
MGSCv37858,797,792 - 58,797,872UniSTSGRCm37
Celera858,975,523 - 58,975,603UniSTS
Cytogenetic Map8B3.2UniSTS
cM Map8 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000034026   ⟹   ENSMUSP00000034026
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl856,747,620 - 56,774,078 (+)Ensembl
GRCm38.p6 Ensembl856,294,585 - 56,321,043 (+)Ensembl
RefSeq Acc Id: NM_008278   ⟹   NP_032304
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39856,747,587 - 56,774,081 (+)NCBI
GRCm38856,294,552 - 56,321,046 (+)ENTREZGENE
MGSCv37858,773,349 - 58,799,843 (+)RGD
Celera858,951,090 - 58,977,585 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_032304 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB41825 (Get FASTA)   NCBI Sequence Viewer  
  AAH21157 (Get FASTA)   NCBI Sequence Viewer  
  BAE26850 (Get FASTA)   NCBI Sequence Viewer  
  EDL28603 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000034026
  ENSMUSP00000034026.9
GenBank Protein Q8VCC1 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_032304   ⟸   NM_008278
- UniProtKB: Q61106 (UniProtKB/Swiss-Prot),   Q8VCC1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000034026   ⟸   ENSMUST00000034026

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VCC1-F1-model_v2 AlphaFold Q8VCC1 1-269 view protein structure

Promoters
RGD ID:8667099
Promoter ID:EPDNEW_M11581
Type:multiple initiation site
Name:Hpgd_1
Description:Mus musculus hydroxyprostaglandin dehydrogenase 15 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38856,294,585 - 56,294,645EPDNEW
RGD ID:6843298
Promoter ID:MM_KWN:54460
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:NM_008278
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36858,773,146 - 58,773,646 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:108085 AgrOrtholog
Ensembl Genes ENSMUSG00000031613 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000034026 ENTREZGENE
  ENSMUST00000034026.10 UniProtKB/Swiss-Prot
Gene3D-CATH NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot
InterPro NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot
  Sc_DH/Rdtase_CS UniProtKB/Swiss-Prot
  SDR_fam UniProtKB/Swiss-Prot
KEGG Report mmu:15446 UniProtKB/Swiss-Prot
MGD MGI:108085 ENTREZGENE
NCBI Gene 15446 ENTREZGENE
PANTHER 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] UniProtKB/Swiss-Prot
  15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] UniProtKB/Swiss-Prot
Pfam adh_short UniProtKB/Swiss-Prot
PhenoGen Hpgd PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot
  SDRFAMILY UniProtKB/Swiss-Prot
PROSITE ADH_SHORT UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51735 UniProtKB/Swiss-Prot
UniProt PGDH_MOUSE UniProtKB/Swiss-Prot
  Q61106 ENTREZGENE
  Q8VCC1 ENTREZGENE
UniProt Secondary Q61106 UniProtKB/Swiss-Prot