Irs2 (insulin receptor substrate 2)

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Keyword

Gene: Irs2 (insulin receptor substrate 2) Mus musculus

Symbol:

Irs2

Name:

insulin receptor substrate 2

Description:

ENCODES a protein that exhibits phosphatidylinositol 3-kinase binding; protein kinase binding; insulin receptor binding (ortholog); INVOLVED IN brain development; cell proliferation; cellular response to insulin stimulus; PARTICIPATES IN leptin system pathway; erythropoietin signaling pathway; insulin signaling pathway; ASSOCIATED WITH abnormal cell differentiation; abnormal circulating glucose level; abnormal circulating hormone level; ASSOCIATED WITH Diabetes Mellitus, Type 2 (ortholog); Insulin Resistance (ortholog); Non-alcoholic Fatty Liver Disease (ortholog); FOUND IN cytosol; plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine; benzo[a]pyrene

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

4PS; insulin receptor substrate 2; Irs-2

Orthologs:

Homo sapiens : IRS2 (insulin receptor substrate 2) HGNC
Rattus norvegicus : Irs2 (insulin receptor substrate 2)

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	8	10,986,961 - 11,008,430	-	NCBI
Mouse cM Map	8	5.35		NCBI
Mouse Celera Assembly	8	11,160,160 - 11,181,560	-	NCBI
Mouse Genome Assembly Build 37	8	10,986,961 - 11,008,430	-	NCBI
Mouse Genome Assembly Build 36.1	8	10,986,961 - 11,008,430	-	NCBI
Mouse Cytogenetic Map	8	A1.1		NCBI