Plekha4 (pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4) - Rat Genome Database

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Gene: Plekha4 (pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4) Mus musculus
Analyze
Symbol: Plekha4
Name: pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
RGD ID: 1552055
MGI Page MGI
Description: Predicted to enable identical protein binding activity; phosphatidylinositol phosphate binding activity; and phosphatidylinositol-3,4-bisphosphate binding activity. Predicted to be involved in positive regulation of Wnt signaling pathway, planar cell polarity pathway and positive regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm and membrane. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in foregut; naris; nervous system; respiratory system cartilage; and turbinate bone primordium. Orthologous to human PLEKHA4 (pleckstrin homology domain containing A4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 2410005C22Rik; C88169; PE; PEPP-1; Pepp1; PH domain-containing family A member 4; phosphoinositol 3-phosphate binding protein-1; phosphoinositol 3-phosphate-binding protein 1; pleckstrin homology domain-containing family A member 4; pleckstrin homology domain-containing, family A member 4
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,175,754 - 45,203,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,175,754 - 45,203,653 (+)EnsemblGRCm39 Ensembl
GRCm38745,526,330 - 45,554,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,526,330 - 45,554,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,781,700 - 52,809,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,398,035 - 45,422,271 (+)NCBIMGSCv36mm8
Celera740,982,828 - 41,010,711 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18799693  
PMID:21267068   PMID:21873635  


Genomics

Comparative Map Data
Plekha4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,175,754 - 45,203,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,175,754 - 45,203,653 (+)EnsemblGRCm39 Ensembl
GRCm38745,526,330 - 45,554,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,526,330 - 45,554,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,781,700 - 52,809,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,398,035 - 45,422,271 (+)NCBIMGSCv36mm8
Celera740,982,828 - 41,010,711 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.34NCBI
PLEKHA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,837,097 - 48,868,617 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,837,092 - 48,868,617 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,340,354 - 49,371,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,032,167 - 54,063,670 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,032,166 - 54,063,670NCBI
Celera1946,207,718 - 46,239,248 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,716,787 - 45,748,327 (-)NCBIHuRef
CHM1_11949,342,240 - 49,373,751 (-)NCBICHM1_1
T2T-CHM13v2.01951,831,976 - 51,863,478 (-)NCBIT2T-CHM13v2.0
Plekha4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,142,296 - 105,165,297 (+)NCBIGRCr8
mRatBN7.2196,005,824 - 96,028,826 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,006,000 - 96,028,826 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,391,484 - 101,414,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,864,162 - 109,886,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,154,554 - 103,177,339 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,517,702 - 101,540,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,517,714 - 101,540,802 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,596,518 - 102,619,582 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,000,020 - 96,024,447 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,078,130 - 96,102,558 (+)NCBI
Celera190,261,747 - 90,284,341 (+)NCBICelera
Cytogenetic Map1q22NCBI
Plekha4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,757,556 - 1,771,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,756,695 - 1,775,558 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,941,667 - 54,973,087 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,867,753 - 56,899,016 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,837,738 - 45,868,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,886,850 - 54,918,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,886,850 - 54,918,334 (+)Ensemblpanpan1.1panPan2
PLEKHA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,491,617 - 107,517,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,492,587 - 107,517,800 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,014,258 - 107,040,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,016,407 - 108,042,600 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,016,431 - 108,042,605 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,683,365 - 107,709,534 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,330,227 - 107,356,423 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,165,850 - 108,192,037 (+)NCBIUU_Cfam_GSD_1.0
Plekha4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,272,089 - 21,290,524 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,890,463 - 2,907,871 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,890,279 - 2,908,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,144,020 - 54,170,638 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,144,016 - 54,170,661 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,891,388 - 49,918,032 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,076,695 - 42,110,904 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607321,958,628 - 21,988,275 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,109,874 - 5,122,521 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,108,928 - 5,133,950 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Plekha4
735 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2438
Count of miRNA genes:703
Interacting mature miRNAs:885
Transcripts:ENSMUST00000051810, ENSMUST00000120516, ENSMUST00000120985, ENSMUST00000121932, ENSMUST00000123978, ENSMUST00000135282, ENSMUST00000138053, ENSMUST00000149052
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300722Sle3_msystemic lupus erythmatosus susceptibility 3 (mouse)Not determined7351172887142720Mouse
38501068Tip1_mtuberculosis immunophenotype 1, spleen CFU (mouse)7360299972549748Mouse
25314307Mlh1fc2_mMLH1 foci count 2 (mouse)76502999133501729Mouse
12792978Fbmd3_mfemoral bone mineral density 3, females only (mouse)77050288142367832Mouse
10449139Eosn1_meosinophil differential 1 (mouse)71248087746480877Mouse
10449158Eosn3_meosinophil differential 3 (mouse)71248087746480877Mouse
4141566Femwf8_mfemur work to failure 8 (mouse)Not determined1303248547032621Mouse
11522751Cocia17_mcocaine-induced activity, QTL 17 (mouse)71313520447135204Mouse
25314314Sccor1_msynaptonemal complex length to mean MLH1 count ratio 1 (mouse)71333392547349748Mouse
1559016Drsi_mDCC-related Spp1 induction (mouse)Not determined71663729349159331Mouse
10412199Sst2_msusceptibility to tuberculosis 2 (mouse)Not determined718728794119485380Mouse
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719147398141919804Mouse
1301622Eae12_msusceptibility to experimental allergic encephalomyelitis 12 (mouse)Not determined71928001553280104Mouse
1301052Bhr6_mbronchial hyperresponsiveness 6 (mouse)Not determined71984225053842367Mouse
12904742Litsq2_mlitter size QTL 2 (mouse)72267388756674033Mouse
1301709Bdt4_mbone density traits 4 (mouse)Not determined72288857256888716Mouse
11354952Pdcc1_mplasmacytoid dentritic cell compartment 1 (mouse)72306653157066531Mouse
1301969Lbw5_mlupus NZB x NZW 5 (mouse)Not determined72684761560851775Mouse
12790989Tgl6_mtriglyceride 6 (mouse)72754054961540549Mouse
4141805Sle19_msystematic lupus erythematosus susceptibility 19 (mouse)Not determined3003248581135653Mouse
26884404Huml1_mhumerus length 1, 5 week (mouse)730199425108999207Mouse
1301175Ap7q_malcohol preference 7 QTL (mouse)Not determined73171484565715077Mouse
1300996Aorls2_maortic lesion size 2 (mouse)Not determined73239453266394681Mouse
4142003W3q10_mweight 3 weeks QTL 10 (mouse)Not determined3349772758148965Mouse
4142102Tailq5_mtail length QTL 5 (mouse)Not determined3349772758148965Mouse
4142218W6q17_mweight 6 weeks QTL 17 (mouse)Not determined3349772758148965Mouse
4141909W10q18_mweight 10 weeks QTL 18 (mouse)Not determined3349772758148965Mouse
1357883Epfq5_mepididymal fat pad weight QTL 5 (mouse)Not determined73349772758148965Mouse
1357634Splq7_mspleen weight QTL 7 (mouse)Not determined73349772758148965Mouse
39128210Lwq19_mliver weight QTL 19 (mouse)73349772758148965Mouse
1357469Kidq5_mkidney weight QTL 5 (mouse)Not determined73349772758148965Mouse
1559000Ossc1_mosteosarcoma susceptibility 1 (mouse)Not determined73405302568053223Mouse
38501071Stsl6_mSalmonella typhimurium susceptibility locus 6 (mouse)73419942551149748Mouse
10045622Heal20_mwound healing/regeneration 20 (mouse)Not determined73431688768317043Mouse
1357586Mdmsc3_mmodifier of muscularity 3 (mouse)Not determined73444786968448018Mouse
1301514Rigs1_mradiation induced gastroschisis 1 (mouse)Not determined73628001592394346Mouse
1301082Bbaa16_mB.burgdorferi-associated arthritis 16 (mouse)Not determined736280015116416877Mouse
25314301Vmm3_mvariable multisystem mineralization 3, lung (mouse)73729942572049748Mouse
25314303Vmm4_mvariable multisystem mineralization 4, kidney (mouse)73729942587049208Mouse
1300878Skts1_mskin tumor susceptibility 1 (mouse)Not determined73789138671891582Mouse
10402488Dipa2_mdrug induced psychomotor activation 2 (mouse)Not determined73842154872421684Mouse
1300791Abbp3_mA/J and C57BL/6 blood pressure 3 (mouse)Not determined739673887103510010Mouse
11252140Fdr1_mfat response to dietary restriction 1 (mouse)74114882075148965Mouse
4141929Chlq18_mcirculating hormone level QTL 18 (mouse)Not determined74114882075148965Mouse
10043926Bw1n_mbody weight 1 in NSY (mouse)Not determined745161966118693530Mouse

Markers in Region
C88169  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38745,554,048 - 45,554,179UniSTSGRCm38
MGSCv37752,809,418 - 52,809,549UniSTSGRCm37
Celera741,010,530 - 41,010,661UniSTS
Cytogenetic Map7B4UniSTS
Whitehead/MRC_RH7565.2UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001381849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_148927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006541166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017312284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036153416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004934185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC151602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK044297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV480955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC030731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC034903 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE652135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG081030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY235943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO044801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000051810   ⟹   ENSMUSP00000051468
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,175,754 - 45,203,653 (+)Ensembl
GRCm38.p6 Ensembl745,526,330 - 45,554,229 (+)Ensembl
RefSeq Acc Id: ENSMUST00000209517   ⟹   ENSMUSP00000148229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,179,529 - 45,203,653 (+)Ensembl
GRCm38.p6 Ensembl745,530,105 - 45,554,229 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210480   ⟹   ENSMUSP00000147680
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,179,464 - 45,181,766 (+)Ensembl
GRCm38.p6 Ensembl745,530,040 - 45,532,342 (+)Ensembl
RefSeq Acc Id: ENSMUST00000210797   ⟹   ENSMUSP00000148244
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,199,259 - 45,203,653 (+)Ensembl
GRCm38.p6 Ensembl745,549,835 - 45,554,229 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211106
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,202,114 - 45,203,653 (+)Ensembl
GRCm38.p6 Ensembl745,552,690 - 45,554,229 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211155   ⟹   ENSMUSP00000147878
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,179,995 - 45,203,456 (+)Ensembl
GRCm38.p6 Ensembl745,530,571 - 45,554,032 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211227   ⟹   ENSMUSP00000148001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,175,754 - 45,198,993 (+)Ensembl
GRCm38.p6 Ensembl745,526,330 - 45,549,569 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211348   ⟹   ENSMUSP00000147799
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,199,313 - 45,203,587 (+)Ensembl
GRCm38.p6 Ensembl745,549,889 - 45,554,163 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211794
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,190,253 - 45,192,667 (+)Ensembl
GRCm38.p6 Ensembl745,540,829 - 45,543,243 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211797   ⟹   ENSMUSP00000147344
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl745,179,417 - 45,203,653 (+)Ensembl
GRCm38.p6 Ensembl745,529,993 - 45,554,229 (+)Ensembl
RefSeq Acc Id: NM_001381849   ⟹   NP_001368778
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,179,023 - 45,203,653 (+)NCBI
GRCm38745,529,599 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: NM_148927   ⟹   NP_683729
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,175,754 - 45,203,653 (+)NCBI
GRCm38745,526,330 - 45,554,229 (+)ENTREZGENE
MGSCv37752,781,700 - 52,809,599 (+)RGD
Celera740,982,828 - 41,010,711 (+)RGD
cM Map7 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006541158   ⟹   XP_006541221
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,294 - 45,203,653 (+)NCBI
GRCm38745,528,870 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006541160   ⟹   XP_006541223
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,294 - 45,203,653 (+)NCBI
GRCm38745,528,869 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006541163   ⟹   XP_006541226
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,179,024 - 45,203,653 (+)NCBI
GRCm38745,529,975 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006541164   ⟹   XP_006541227
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,294 - 45,203,653 (+)NCBI
GRCm38745,528,869 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006541165   ⟹   XP_006541228
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,294 - 45,203,653 (+)NCBI
GRCm38745,528,869 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006541166   ⟹   XP_006541229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,294 - 45,203,653 (+)NCBI
GRCm38745,528,868 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017312284   ⟹   XP_017167773
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,179,024 - 45,203,653 (+)NCBI
GRCm38745,529,975 - 45,554,229 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036153416   ⟹   XP_036009309
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,717 - 45,203,653 (+)NCBI
Sequence:
RefSeq Acc Id: XR_004934185
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39745,178,292 - 45,203,653 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_683729   ⟸   NM_148927
- UniProtKB: D3Z3Y7 (UniProtKB/TrEMBL),   D3YTU1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006541229   ⟸   XM_006541166
- Peptide Label: isoform X7
- UniProtKB: A0A1B0GSM9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006541228   ⟸   XM_006541165
- Peptide Label: isoform X6
- UniProtKB: A0A1B0GSC3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006541227   ⟸   XM_006541164
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_006541223   ⟸   XM_006541160
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006541221   ⟸   XM_006541158
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006541226   ⟸   XM_006541163
- Peptide Label: isoform X4
- UniProtKB: D3Z3Y7 (UniProtKB/TrEMBL),   D3YTU1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017167773   ⟸   XM_017312284
- Peptide Label: isoform X8
- Sequence:
RefSeq Acc Id: NP_001368778   ⟸   NM_001381849
- UniProtKB: D3YTU1 (UniProtKB/TrEMBL),   D3Z3Y7 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000051468   ⟸   ENSMUST00000051810
RefSeq Acc Id: ENSMUSP00000147344   ⟸   ENSMUST00000211797
RefSeq Acc Id: ENSMUSP00000147799   ⟸   ENSMUST00000211348
RefSeq Acc Id: ENSMUSP00000148001   ⟸   ENSMUST00000211227
RefSeq Acc Id: ENSMUSP00000147878   ⟸   ENSMUST00000211155
RefSeq Acc Id: ENSMUSP00000148244   ⟸   ENSMUST00000210797
RefSeq Acc Id: ENSMUSP00000147680   ⟸   ENSMUST00000210480
RefSeq Acc Id: ENSMUSP00000148229   ⟸   ENSMUST00000209517
RefSeq Acc Id: XP_036009309   ⟸   XM_036153416
- Peptide Label: isoform X3
Protein Domains
PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8VC98-F1-model_v2 AlphaFold Q8VC98 1-588 view protein structure

Promoters
RGD ID:8664039
Promoter ID:EPDNEW_M10051
Type:initiation region
Name:Plekha4_2
Description:Mus musculus pleckstrin homology domain containing, family Amember 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10052  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38745,526,335 - 45,526,395EPDNEW
RGD ID:8664043
Promoter ID:EPDNEW_M10052
Type:initiation region
Name:Plekha4_1
Description:Mus musculus pleckstrin homology domain containing, family Amember 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M10051  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38745,549,865 - 45,549,925EPDNEW
RGD ID:6841777
Promoter ID:MM_KWN:50417
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000098456,   ENSMUST00000120985,   NM_148927,   OTTMUST00000060014,   OTTMUST00000060016,   UC009GVT.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,778,151 - 52,781,892 (+)MPROMDB
RGD ID:6841761
Promoter ID:MM_KWN:50418
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000051810,   ENSMUST00000053942,   ENSMUST00000120516,   ENSMUST00000121932,   OTTMUST00000072289,   OTTMUST00000072294
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,784,406 - 52,785,057 (+)MPROMDB
RGD ID:6841763
Promoter ID:MM_KWN:50419
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:UC009GVX.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,793,484 - 52,793,984 (+)MPROMDB
RGD ID:6841764
Promoter ID:MM_KWN:50420
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:UC009GVY.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36752,805,316 - 52,805,816 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916467 AgrOrtholog
Ensembl Genes ENSMUSG00000040428 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000051810 ENTREZGENE
  ENSMUST00000051810.15 UniProtKB/TrEMBL
  ENSMUST00000209517 ENTREZGENE
  ENSMUST00000209517.2 UniProtKB/TrEMBL
  ENSMUST00000210480.2 UniProtKB/TrEMBL
  ENSMUST00000210797.2 UniProtKB/TrEMBL
  ENSMUST00000211155 ENTREZGENE
  ENSMUST00000211155.2 UniProtKB/TrEMBL
  ENSMUST00000211227.2 UniProtKB/TrEMBL
  ENSMUST00000211348.2 UniProtKB/TrEMBL
  ENSMUST00000211797.2 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PH_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PKHA4/5/6/7_PH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1916467 ENTREZGENE
NCBI Gene 69217 ENTREZGENE
PANTHER PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PF00169 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Plekha4 PhenoGen
PROSITE PH_DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART SM00233 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1B0GR22_MOUSE UniProtKB/TrEMBL
  A0A1B0GRV6_MOUSE UniProtKB/TrEMBL
  A0A1B0GS55_MOUSE UniProtKB/TrEMBL
  A0A1B0GSC3 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GSM9 ENTREZGENE, UniProtKB/TrEMBL
  A0A1B0GT85_MOUSE UniProtKB/TrEMBL
  D3YTU1 ENTREZGENE
  D3Z3Y7 ENTREZGENE, UniProtKB/TrEMBL
  PKHA4_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary D3YTU1 UniProtKB/TrEMBL
  Q8R3N3 UniProtKB/Swiss-Prot