Plekha4 (pleckstrin homology domain containing A4) - Rat Genome Database

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Gene: Plekha4 (pleckstrin homology domain containing A4) Ictidomys tridecemlineatus
Analyze
Symbol: Plekha4
Name: pleckstrin homology domain containing A4
RGD ID: 12615304
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN positive regulation of canonical Wnt signaling pathway (inferred); positive regulation of Wnt signaling pathway, planar cell polarity pathway (inferred); ASSOCIATED WITH genetic disease (ortholog); prostate cancer (ortholog); FOUND IN extrinsic component of cytoplasmic side of plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pleckstrin homology domain-containing family A member 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,272,089 - 21,290,524 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,890,463 - 2,907,871 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,890,279 - 2,908,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

Genomics

Comparative Map Data
Plekha4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,272,089 - 21,290,524 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366642,890,463 - 2,907,871 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366642,890,279 - 2,908,423 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLEKHA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381948,837,097 - 48,868,617 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1948,837,092 - 48,868,617 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,340,354 - 49,371,874 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,032,167 - 54,063,670 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,032,166 - 54,063,670NCBI
Celera1946,207,718 - 46,239,248 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1945,716,787 - 45,748,327 (-)NCBIHuRef
CHM1_11949,342,240 - 49,373,751 (-)NCBICHM1_1
T2T-CHM13v2.01951,831,976 - 51,863,478 (-)NCBIT2T-CHM13v2.0
Plekha4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39745,175,754 - 45,203,653 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl745,175,754 - 45,203,653 (+)EnsemblGRCm39 Ensembl
GRCm38745,526,330 - 45,554,229 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,526,330 - 45,554,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,781,700 - 52,809,599 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,398,035 - 45,422,271 (+)NCBIMGSCv36mm8
Celera740,982,828 - 41,010,711 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.34NCBI
Plekha4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81105,142,296 - 105,165,297 (+)NCBIGRCr8
mRatBN7.2196,005,824 - 96,028,826 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl196,006,000 - 96,028,826 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,391,484 - 101,414,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,864,162 - 109,886,947 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01103,154,554 - 103,177,339 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,517,702 - 101,540,802 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,517,714 - 101,540,802 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,596,518 - 102,619,582 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4196,000,020 - 96,024,447 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1196,078,130 - 96,102,558 (+)NCBI
Celera190,261,747 - 90,284,341 (+)NCBICelera
Cytogenetic Map1q22NCBI
Plekha4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,757,556 - 1,771,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,756,695 - 1,775,558 (+)NCBIChiLan1.0ChiLan1.0
PLEKHA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22054,941,667 - 54,973,087 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11956,867,753 - 56,899,016 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01945,837,738 - 45,868,961 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11954,886,850 - 54,918,339 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1954,886,850 - 54,918,334 (+)Ensemblpanpan1.1panPan2
PLEKHA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,491,617 - 107,517,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,492,587 - 107,517,800 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,014,258 - 107,040,442 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,016,407 - 108,042,600 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,016,431 - 108,042,605 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,683,365 - 107,709,534 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01107,330,227 - 107,356,423 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01108,165,850 - 108,192,037 (+)NCBIUU_Cfam_GSD_1.0
PLEKHA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,144,020 - 54,170,638 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,144,016 - 54,170,661 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2649,891,388 - 49,918,032 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PLEKHA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,076,695 - 42,110,904 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607321,958,628 - 21,988,275 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Plekha4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248325,109,874 - 5,122,521 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248325,108,928 - 5,133,950 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSSTOT00000004402   ⟹   ENSSTOP00000003948
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366642,890,463 - 2,907,871 (-)Ensembl
RefSeq Acc Id: XM_040278993   ⟹   XP_040134927
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440934921,272,089 - 21,290,524 (-)NCBI
Protein Sequences
Protein RefSeqs XP_040134927 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000003948.3
GenBank Protein KAG3256458 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_040134927   ⟸   XM_040278993
- UniProtKB: I3M462 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSSTOP00000003948   ⟸   ENSSTOT00000004402
Protein Domains
PH


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000004387 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000004402.3 UniProtKB/TrEMBL
Gene3D-CATH 2.30.29.30 UniProtKB/TrEMBL
InterPro PH-like_dom_sf UniProtKB/TrEMBL
  PH_domain UniProtKB/TrEMBL
NCBI Gene Plekha4 ENTREZGENE
PANTHER PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN UniProtKB/TrEMBL
  PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY A MEMBER 4 UniProtKB/TrEMBL
PROSITE PH_DOMAIN UniProtKB/TrEMBL
Superfamily-SCOP PH domain-like UniProtKB/TrEMBL
UniProt I3M462 ENTREZGENE, UniProtKB/TrEMBL