Krt14 (keratin 14) - Rat Genome Database

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Gene: Krt14 (keratin 14) Mus musculus
Analyze
Symbol: Krt14
Name: keratin 14
RGD ID: 1316672
MGI Page MGI
Description: Predicted to enable keratin filament binding activity. Acts upstream of or within keratinocyte differentiation; response to radiation; and stem cell differentiation. Located in basal part of cell; cell periphery; and keratin filament. Is active in cornified envelope. Is expressed in several structures, including alimentary system; autopod; genitourinary system; integumental system; and sensory organ. Used to study epidermolysis bullosa simplex and epidermolysis bullosa simplex Dowling-Meara type. Human ortholog(s) of this gene implicated in Naegeli-Franceschetti-Jadassohn syndrome; dermatopathia pigmentosa reticularis; and epidermolysis bullosa simplex. Orthologous to human KRT14 (keratin 14).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: AI626930; CK-14; cytokeratin 14; cytokeratin-14; epidermolysis bullosa simplex, Dowling-Meara, Koebner; K14; keratin complex 1, acidic, gene 14; keratin, type I cytoskeletal 14; keratin-14; Krt-1.1; Krt-1.14; Krt1-1; Krt1-14
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,093,988 - 100,098,336 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,093,988 - 100,098,374 (-)EnsemblGRCm39 Ensembl
GRCm3811100,203,162 - 100,207,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,203,162 - 100,207,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,064,476 - 100,068,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,019,252 - 100,023,600 (-)NCBIMGSCv36mm8
Celera11110,819,617 - 110,823,965 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
2-nitroanisole  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-Amino-2-nitrophenol  (ISO)
9-cis-retinoic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-4-oxoretinoic acid  (ISO)
all-trans-retinoic acid  (ISO)
alpha-naphthoflavone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
aristolochic acids  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
cadmium sulfate  (ISO)
calcidiol  (ISO)
chlordecone  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
dexamethasone  (EXP)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
Disperse Blue 1  (ISO)
diuron  (ISO)
endosulfan  (ISO)
enzyme inhibitor  (ISO)
fenamic acid  (ISO)
folic acid  (ISO)
furan  (ISO)
genistein  (EXP)
glycidyl methacrylate  (ISO)
graphite  (EXP)
indole-3-methanol  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
lead nitrate  (EXP)
lead(0)  (ISO)
malathion  (ISO)
melamine  (ISO)
methamphetamine  (ISO)
methimazole  (ISO)
N,N-bis(2-hydroxypropyl)nitrosamine  (ISO)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosomorpholine  (ISO)
nickel atom  (ISO)
para-Cresidine  (ISO)
paracetamol  (ISO)
pentane-2,3-dione  (ISO)
perfluorododecanoic acid  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
phenyl isocyanate  (ISO)
phenylbutazone  (ISO)
resveratrol  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sodium fluoride  (EXP)
sulindac sulfide  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
triclosan  (EXP)
troglitazone  (ISO)
uracil  (ISO)
zinc atom  (EXP,ISO)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal adipose tissue physiology  (IAGP)
abnormal coat/ hair morphology  (IAGP)
abnormal ear morphology  (IAGP)
abnormal epidermal layer morphology  (IAGP)
abnormal epidermal melanocyte morphology  (IAGP)
abnormal epidermis stratum basale morphology  (IAGP)
abnormal epidermis stratum corneum morphology  (IAGP)
abnormal esophagus morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal hair follicle melanocyte morphology  (IAGP)
abnormal hair follicle morphology  (IAGP)
abnormal hair follicle orientation  (IAGP)
abnormal hair growth  (IAGP)
abnormal head skin morphology  (IAGP)
abnormal keratinocyte apoptosis  (IAGP)
abnormal keratinocyte differentiation  (IAGP)
abnormal keratinocyte morphology  (IAGP)
abnormal melanocyte morphology  (IAGP)
abnormal nose morphology  (IAGP)
abnormal skin appearance  (IAGP)
abnormal skin physiology  (IAGP)
abnormal T cell differentiation  (IAGP)
abnormal T cell physiology  (IAGP)
abnormal T cell subpopulation ratio  (IAGP)
abnormal trachea morphology  (IAGP)
abnormal vagina epithelium morphology  (IAGP)
absent sebaceous gland  (IAGP)
acanthosis  (IAGP)
alopecia  (IAGP)
anophthalmia  (IEA)
blistering  (IAGP)
cutaneous mastocytosis  (IAGP)
darkened coat color  (IAGP)
decreased body size  (IAGP)
decreased body surface temperature  (IAGP)
decreased corneal epithelium thickness  (IAGP)
decreased curvature of zigzag hairs  (IAGP)
decreased double-positive T cell number  (IAGP)
decreased gamma-delta T cell number  (IAGP)
decreased hair follicle number  (IAGP)
decreased incidence of tumors by chemical induction  (IAGP)
decreased keratinocyte proliferation  (IAGP)
decreased survivor rate  (IAGP)
decreased T cell number  (IAGP)
decreased thymus weight  (IAGP)
decreased tumor growth/size  (IAGP)
decreased tumor latency  (IAGP)
decreased tumor-free survival time  (IAGP)
decreased zigzag hair amount  (IAGP)
dermatitis  (IAGP)
dry skin  (IAGP)
enhanced wound healing  (IAGP)
epidermal spongiosis  (IAGP)
flaky skin  (IAGP)
focal dorsal hair loss  (IAGP)
hair follicle degeneration  (IAGP)
hemorrhage  (IEA)
hyperkeratosis  (IAGP)
impaired skin barrier function  (IAGP)
increased basal cell carcinoma incidence  (IAGP)
increased double-negative T cell number  (IAGP)
increased hair follicle number  (IAGP)
increased incidence of tumors by chemical induction  (IAGP)
increased keratinocyte migration  (IAGP)
increased keratinocyte proliferation  (IAGP)
increased macrophage cell number  (IAGP)
increased melanocyte number  (IAGP)
increased metastatic potential  (IAGP)
increased neutrophil cell number  (IAGP)
increased salivary gland tumor incidence  (IAGP)
increased sebaceous gland tumor incidence  (IAGP)
increased skin papilloma incidence  (IAGP)
increased skin squamous cell carcinoma incidence  (IAGP)
increased skin tumor incidence  (IAGP)
increased squamous cell carcinoma incidence  (IAGP)
increased T cell proliferation  (IAGP)
increased tumor growth/size  (IAGP)
increased tumor latency  (IAGP)
microcephaly  (IEA)
microphthalmia  (IEA)
parakeratosis  (IAGP)
polydactyly  (IEA)
postnatal growth retardation  (IAGP)
postnatal lethality, complete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
preweaning lethality, complete penetrance  (IEA)
psoriasis  (IAGP)
reddish skin  (IAGP)
rough coat  (IAGP)
scaly skin  (IAGP)
skin inflammation  (IAGP)
skin lesions  (IAGP)
small thymus medulla  (IAGP)
sparse hair  (IAGP)
spina bifida  (IEA)
syndactyly  (IEA)
thick epidermis  (IAGP)
thick skin  (IAGP)
thin dermal layer  (IAGP)
thin epidermis  (IAGP)
thin hypodermis  (IAGP)
thin skin  (IAGP)
thymus atrophy  (IAGP)
thymus hypoplasia  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Coulombe PA, etal., Cell. 1991 Sep 20;66(6):1301-11.
2. Transgenic rats overexpressing the human MrgX3 gene show cataracts and an abnormal skin phenotype. Kaisho Y, etal., Biochem Biophys Res Commun. 2005 May 13;330(3):653-7.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Modulation of gene expression in precancerous rat esophagus by dietary zinc deficit and replenishment. Liu CG, etal., Cancer Res. 2005 Sep 1;65(17):7790-9.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Mouse MP Annotation Import Pipeline RGD automated import pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. The genomic organization of type I keratin genes in mice. Sato H, etal., Genomics 1999 Mar 15;56(3):303-9.
Additional References at PubMed
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PMID:33082503   PMID:33132190   PMID:33294854   PMID:33305192   PMID:33318148   PMID:33328632   PMID:33452256   PMID:33470495   PMID:33495473   PMID:33567267   PMID:33637728   PMID:33882290  
PMID:34009125   PMID:34041875   PMID:34050161   PMID:34078823   PMID:34107258   PMID:34111600   PMID:34361001   PMID:34474245   PMID:34653670   PMID:34733164   PMID:34905516   PMID:34995520  
PMID:34998785   PMID:35247391   PMID:35283102   PMID:35302059   PMID:35585237   PMID:35902588   PMID:35941116   PMID:35966594   PMID:36006534   PMID:36049534   PMID:36116371   PMID:36136514  
PMID:36272714   PMID:36330928   PMID:36512409   PMID:36520901   PMID:36606449   PMID:36630508   PMID:36693323   PMID:36751050   PMID:36764291   PMID:36804570   PMID:36856110   PMID:36961889  
PMID:37017303   PMID:37115925   PMID:37367826   PMID:37591247   PMID:37625561   PMID:37647896   PMID:37660780   PMID:37715952   PMID:37813160   PMID:37868985   PMID:38159590   PMID:38169606  
PMID:38517430  


Genomics

Comparative Map Data
Krt14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911100,093,988 - 100,098,336 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11100,093,988 - 100,098,374 (-)EnsemblGRCm39 Ensembl
GRCm3811100,203,162 - 100,207,510 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11100,203,162 - 100,207,548 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711100,064,476 - 100,068,824 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611100,019,252 - 100,023,600 (-)NCBIMGSCv36mm8
Celera11110,819,617 - 110,823,965 (-)NCBICelera
Cytogenetic Map11DNCBI
cM Map1163.43NCBI
KRT14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381741,582,279 - 41,586,895 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1741,582,279 - 41,586,895 (-)EnsemblGRCh38hg38GRCh38
GRCh371739,738,531 - 39,743,147 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361736,992,059 - 36,996,673 (-)NCBINCBI36Build 36hg18NCBI36
Build 341736,992,058 - 36,996,673NCBI
Celera1736,391,486 - 36,396,102 (-)NCBICelera
Cytogenetic Map17q21.2NCBI
HuRef1735,501,649 - 35,506,252 (-)NCBIHuRef
CHM1_11739,973,838 - 39,978,454 (-)NCBICHM1_1
T2T-CHM13v2.01742,437,869 - 42,442,485 (-)NCBIT2T-CHM13v2.0
Krt14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81085,638,182 - 85,642,450 (-)NCBIGRCr8
mRatBN7.21085,137,786 - 85,142,054 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1085,066,802 - 85,171,799 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1090,155,919 - 90,159,989 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01089,654,291 - 89,658,349 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01085,046,229 - 85,050,287 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01088,118,029 - 88,122,233 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1088,055,823 - 88,122,233 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01087,910,658 - 87,914,716 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41089,144,357 - 89,148,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11089,158,726 - 89,162,785 (-)NCBI
Celera1083,857,265 - 83,861,323 (-)NCBICelera
Cytogenetic Map10q31NCBI
LOC100975309
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21923,398,101 - 23,402,706 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11725,288,234 - 25,292,839 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01715,730,066 - 15,734,665 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11715,948,570 - 15,953,191 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1715,948,596 - 15,953,191 (+)Ensemblpanpan1.1panPan2
KRT14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1921,190,672 - 21,195,060 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl921,156,045 - 21,265,564 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha920,652,119 - 20,656,507 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0921,911,274 - 21,915,662 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1920,697,290 - 20,701,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0920,963,294 - 20,967,682 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0921,067,094 - 21,071,483 (+)NCBIUU_Cfam_GSD_1.0
LOC110255312
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1221,024,314 - 21,119,396 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11221,074,965 - 21,079,393 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103243443
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11664,654,988 - 64,660,327 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1664,655,807 - 64,660,319 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607735,500,284 - 35,505,086 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Krt14
133 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:405
Count of miRNA genes:301
Interacting mature miRNAs:346
Transcripts:ENSMUST00000007272, ENSMUST00000137265
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
1301983Berr2_mberghei resistance locus 2 (mouse)Not determined1198352609121973369Mouse
10043976Obq33_mobesity QTL 33 (mouse)Not determined1198500469121973369Mouse
10044001Alcw8_malcohol withdrawal 8 (mouse)Not determined1199254187121973369Mouse
13513918Heal55_mwound healing/ regeneration 55 (mouse)1199672251100232454Mouse
11553867Stmm5_mskin tumor modifier of MSM 5 (mouse)11100058103121973369Mouse

Markers in Region
AI626930  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811100,203,233 - 100,203,326UniSTSGRCm38
MGSCv3711100,064,547 - 100,064,640UniSTSGRCm37
Celera11110,819,688 - 110,819,781UniSTS
Cytogenetic Map11DUniSTS
cM Map1158.6UniSTS
Whitehead/MRC_RH111330.57UniSTS
G16019  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811100,207,086 - 100,207,302UniSTSGRCm38
GRCm3811100,248,545 - 100,248,737UniSTSGRCm38
MGSCv3711100,068,400 - 100,068,616UniSTSGRCm37
MGSCv3711100,109,859 - 100,110,051UniSTSGRCm37
Celera11110,865,859 - 110,866,051UniSTS
Celera11110,823,541 - 110,823,757UniSTS
Cytogenetic Map11DUniSTS
cM Map1158.6UniSTS
Krt1-14  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3811100,203,164 - 100,203,391UniSTSGRCm38
MGSCv3711100,064,478 - 100,064,705UniSTSGRCm37
Celera11110,819,619 - 110,819,846UniSTS
Cytogenetic Map11DUniSTS
cM Map1158.6UniSTS
Krt16  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11DUniSTS
cM Map1158.6UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000007272   ⟹   ENSMUSP00000007272
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11100,093,988 - 100,098,374 (-)Ensembl
GRCm38.p6 Ensembl11100,203,162 - 100,207,548 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137265
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl11100,093,988 - 100,096,856 (-)Ensembl
GRCm38.p6 Ensembl11100,203,162 - 100,206,030 (-)Ensembl
RefSeq Acc Id: NM_001313956   ⟹   NP_001300885
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911100,093,988 - 100,098,336 (-)NCBI
GRCm3811100,203,162 - 100,207,510 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001313957   ⟹   NP_001300886
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911100,093,988 - 100,096,856 (-)NCBI
GRCm3811100,203,162 - 100,206,030 (-)NCBI
Sequence:
RefSeq Acc Id: NM_016958   ⟹   NP_058654
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3911100,093,988 - 100,098,336 (-)NCBI
GRCm3811100,203,162 - 100,207,510 (-)ENTREZGENE
MGSCv3711100,064,476 - 100,068,824 (-)RGD
Celera11110,819,617 - 110,823,965 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001300885 (Get FASTA)   NCBI Sequence Viewer  
  NP_001300886 (Get FASTA)   NCBI Sequence Viewer  
  NP_058654 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA39392 (Get FASTA)   NCBI Sequence Viewer  
  AAH03325 (Get FASTA)   NCBI Sequence Viewer  
  AAH11074 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000007272
  ENSMUSP00000007272.8
GenBank Protein Q61781 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_058654   ⟸   NM_016958
- Peptide Label: isoform 1
- UniProtKB: Q91VQ4 (UniProtKB/Swiss-Prot),   A2A4G4 (UniProtKB/Swiss-Prot),   Q99LE0 (UniProtKB/Swiss-Prot),   Q61781 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001300885   ⟸   NM_001313956
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_001300886   ⟸   NM_001313957
- Peptide Label: isoform 3
- UniProtKB: Q61781 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000007272   ⟸   ENSMUST00000007272
Protein Domains
IF rod

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61781-F1-model_v2 AlphaFold Q61781 1-484 view protein structure

Promoters
RGD ID:8676668
Promoter ID:EPDNEW_M16365
Type:multiple initiation site
Name:Krt14_1
Description:Mus musculus keratin 14 , transcript variant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3811100,207,519 - 100,207,579EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96688 AgrOrtholog
Ensembl Genes ENSMUSG00000045545 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000007272 ENTREZGENE
  ENSMUST00000007272.8 UniProtKB/Swiss-Prot
  ENSMUST00000137265 ENTREZGENE
Gene3D-CATH 1.20.5.170 UniProtKB/Swiss-Prot
  Single helix bin UniProtKB/Swiss-Prot
  Vasodilator-stimulated phosphoprotein UniProtKB/Swiss-Prot
InterPro IF_conserved UniProtKB/Swiss-Prot
  IF_rod_dom UniProtKB/Swiss-Prot
  Keratin_I UniProtKB/Swiss-Prot
KEGG Report mmu:16664 UniProtKB/Swiss-Prot
MGD MGI:96688 ENTREZGENE
NCBI Gene 16664 ENTREZGENE
PANTHER KERATIN, TYPE I CYTOSKELETAL 14 UniProtKB/Swiss-Prot
  PTHR23239 UniProtKB/Swiss-Prot
Pfam Filament UniProtKB/Swiss-Prot
PhenoGen Krt14 PhenoGen
PRINTS TYPE1KERATIN UniProtKB/Swiss-Prot
PROSITE IF_ROD_1 UniProtKB/Swiss-Prot
  IF_ROD_2 UniProtKB/Swiss-Prot
SMART Filament UniProtKB/Swiss-Prot
Superfamily-SCOP Intermediate filament protein, coiled coil region UniProtKB/Swiss-Prot
  Prefoldin UniProtKB/Swiss-Prot
UniProt A2A4G4 ENTREZGENE
  K1C14_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q91VQ4 ENTREZGENE
  Q99LE0 ENTREZGENE
UniProt Secondary A2A4G4 UniProtKB/Swiss-Prot
  Q91VQ4 UniProtKB/Swiss-Prot
  Q99LE0 UniProtKB/Swiss-Prot