Gene: Hcn4 (hyperpolarization-activated, cyclic nucleotide-gated K+ 4) Mus musculus
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Symbol: Hcn4
Name: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Description: ENCODES a protein that exhibits intracellular cAMP activated cation channel activity; identical protein binding (ortholog); voltage-gated potassium channel activity (ortholog); INVOLVED IN cation transport; in utero embryonic development; regulation of heart contraction; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH abnormal heart rate; abnormal impulse conducting system conduction; abnormal nervous system electrophysiology; ASSOCIATED WITH Arrhythmias, Cardiac (ortholog); arrhythmogenic right ventricular cardiomyopathy (ortholog); Arrhythmogenic Right Ventricular Dysplasia (ortholog); FOUND IN axon; basolateral plasma membrane (ortholog); HCN channel complex (ortholog); INTERACTS WITH choline; folic acid; L-methionine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: BCNG-3; Bcng3; brain cyclic nucleotide-gated channel 3; Hcn3; hyperpolarization-activated, cyclic nucleotide-gated K+ 3; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38958,823,512 - 58,860,955 (+)NCBIGRCm38mm10GRCm38
MGSCv37958,671,319 - 58,708,762 (+)NCBIGRCm37mm9NCBIm37
MGSCv36958,621,649 - 58,659,092 (+)NCBImm8
Celera956,052,112 - 56,089,597 (+)NCBI
Cytogenetic Map9 BNCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hcn4
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
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Vista + UCSC

RGD Object Information
RGD ID: 737127
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2017-05-30
Status: ACTIVE