Dync1h1 (dynein cytoplasmic 1 heavy chain 1) - Rat Genome Database

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Gene: Dync1h1 (dynein cytoplasmic 1 heavy chain 1) Mus musculus
Analyze
Symbol: Dync1h1
Name: dynein cytoplasmic 1 heavy chain 1
RGD ID: 1332334
MGI Page MGI
Description: Enables dynein light intermediate chain binding activity. Involved in P-body assembly; positive regulation of cold-induced thermogenesis; and stress granule assembly. Located in cytoplasm and filopodium. Is expressed in several structures, including early conceptus; nervous system; neural retina; placenta; and spleen. Used to study Charcot-Marie-Tooth disease axonal type 2O. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2O; autosomal dominant intellectual developmental disorder 13; and spinal muscular atrophy with lower extremity predominant 1. Orthologous to human DYNC1H1 (dynein cytoplasmic 1 heavy chain 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 9930018I23Rik; AI894280; cytoplasmic dynein 1 heavy chain 1; cytoplasmic dynein heavy chain 1; DHC1; DHC1a; Dnchc; Dnchc1; DNCL; Dnec; Dnec1; Dnecl; dynein heavy chain, cytosolic; dynein heavy chain, retrograde transport; dynein, cytoplasmic, heavy chain 1; legs at odd angle; Loa; MAP; MAP1C; mKIAA0325; P22; S; sprawling; Swl
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,567,829 - 110,633,378 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12110,567,886 - 110,633,379 (+)EnsemblGRCm39 Ensembl
GRCm3812110,601,395 - 110,666,944 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,601,452 - 110,666,945 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712111,839,605 - 111,905,154 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,049,261 - 111,114,731 (+)NCBIMGSCv36mm8
Celera12111,791,744 - 111,857,176 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.7NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
atrophic muscular disease  (ISO)
autism spectrum disorder  (ISO)
autosomal dominant cerebellar ataxia  (ISO)
autosomal dominant distal hereditary motor neuronopathy  (ISO)
autosomal dominant distal hereditary motor neuronopathy 14  (ISO)
autosomal dominant intellectual developmental disorder 13  (ISO)
cerebellar ataxia  (ISO)
cerebellar hypoplasia  (ISO)
Charcot-Marie-Tooth disease  (ISO)
Charcot-Marie-Tooth disease axonal type 2O  (IAGP,ISO)
Charcot-Marie-Tooth disease type 1  (ISO)
Charcot-Marie-Tooth disease type 2  (ISO)
Charcot-Marie-Tooth disease type 4  (ISO)
Charcot-Marie-Tooth disease type 5  (ISO)
childhood spinal muscular atrophy  (ISO)
complex cortical dysplasia with other brain malformations  (ISO)
Developmental Disabilities  (ISO)
epilepsy  (ISO)
fetal akinesia deformation sequence syndrome 1  (ISO)
genetic disease  (ISO)
intellectual disability  (ISO)
lissencephaly  (ISO)
microcephaly  (ISO)
motor peripheral neuropathy  (ISO)
Muscle Weakness  (ISO)
muscular disease  (ISO)
myopathy  (ISO)
Nervous System Malformations  (ISO)
NEURODEVELOPMENTAL DISORDER WITH MICROCEPHALY, ARTHROGRYPOSIS, AND STRUCTURAL BRAIN ANOMALIES  (ISO)
Neurodevelopmental Disorders  (ISO)
neuropathy  (ISO)
peripheral nervous system disease  (ISO)
polyneuropathy  (ISO)
spinal muscular atrophy  (ISO)
spinal muscular atrophy with predominant lower extremity  (ISO)
spinal muscular atrophy with predominant lower extremity 1  (ISO)
Spinocerebellar Ataxias  (ISO)
Talipes Cavus  (ISO)
thyroid gland papillary carcinoma  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
1,3-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
2-palmitoylglycerol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (ISO)
acrolein  (ISO)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (ISO)
amphetamine  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
caffeine  (ISO)
cisplatin  (ISO)
clobetasol  (EXP)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dioxygen  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
emodin  (EXP)
enzyme inhibitor  (ISO)
ethanol  (EXP)
ethyl methanesulfonate  (ISO)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gemcitabine  (ISO)
gentamycin  (ISO)
glyphosate  (ISO)
hexadecanoic acid  (ISO)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
LY294002  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
miconazole  (EXP)
morphine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-ethyl-N-nitrosourea  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (ISO)
oleic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP)
pentachlorophenol  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
phenylmercury acetate  (ISO)
piroxicam  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sulforaphane  (EXP)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
titanium dioxide  (EXP)
toluene  (ISO)
torcetrapib  (ISO)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
vitamin E  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. Effect of Alzheimer's brain extracts on dynein immunoreactivity in PC12 cells. Kopec K and Chambers JP, Proc Soc Exp Biol Med. 1997 Dec;216(3):429-37.
3. Regulation of mitochondrial transport in neurons. Lin MY and Sheng ZH, Exp Cell Res. 2015 May 15;334(1):35-44. doi: 10.1016/j.yexcr.2015.01.004. Epub 2015 Jan 19.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Molecular cloning of the retrograde transport motor cytoplasmic dynein (MAP 1C). Mikami A, etal., Neuron 1993 May;10(5):787-96.
8. Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48.
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
11. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
Additional References at PubMed
PMID:885789   PMID:894335   PMID:2168780   PMID:4274920   PMID:6449566   PMID:7441297   PMID:8001984   PMID:8870834   PMID:8889548   PMID:9373155   PMID:9531547   PMID:9887344  
PMID:10349636   PMID:10922068   PMID:10932192   PMID:11042159   PMID:11076861   PMID:11172053   PMID:11217851   PMID:11403965   PMID:11734602   PMID:11867214   PMID:12477932   PMID:12520002  
PMID:12730604   PMID:12904583   PMID:12950100   PMID:14610273   PMID:15208636   PMID:15567146   PMID:15762842   PMID:15980862   PMID:16036435   PMID:16141072   PMID:16141073   PMID:16203747  
PMID:16260502   PMID:16267818   PMID:16309881   PMID:16427626   PMID:16440056   PMID:16496424   PMID:16512683   PMID:16575184   PMID:16919471   PMID:16959763   PMID:17574766   PMID:17676955  
PMID:17901046   PMID:18160659   PMID:18202255   PMID:18331715   PMID:18373888   PMID:18719118   PMID:18782860   PMID:18952079   PMID:19525941   PMID:19593442   PMID:19657041   PMID:19825938  
PMID:20360068   PMID:20382740   PMID:20807776   PMID:20887786   PMID:21059924   PMID:21102439   PMID:21267068   PMID:21335237   PMID:21346813   PMID:21612657   PMID:21677750   PMID:21873635  
PMID:22083510   PMID:22582169   PMID:22684941   PMID:22794259   PMID:22840395   PMID:22887640   PMID:22922362   PMID:22956769   PMID:23589491   PMID:23742762   PMID:23900073   PMID:24457600  
PMID:25552654   PMID:25737280   PMID:25915474   PMID:26025364   PMID:27080913   PMID:27103069   PMID:27210554   PMID:27477284   PMID:27507650   PMID:28378742   PMID:28671696   PMID:28706196  
PMID:29229923   PMID:29379136   PMID:29459677   PMID:29688375   PMID:30333137   PMID:30457570   PMID:30562941   PMID:31427617   PMID:32325033   PMID:33601422   PMID:33705456   PMID:34807236  
PMID:36218033   PMID:36293380   PMID:36973253  


Genomics

Comparative Map Data
Dync1h1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3912110,567,829 - 110,633,378 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl12110,567,886 - 110,633,379 (+)EnsemblGRCm39 Ensembl
GRCm3812110,601,395 - 110,666,944 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl12110,601,452 - 110,666,945 (+)EnsemblGRCm38mm10GRCm38
MGSCv3712111,839,605 - 111,905,154 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3612111,049,261 - 111,114,731 (+)NCBIMGSCv36mm8
Celera12111,791,744 - 111,857,176 (+)NCBICelera
Cytogenetic Map12F1NCBI
cM Map1260.7NCBI
DYNC1H1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3814101,964,573 - 102,056,443 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl14101,964,573 - 102,056,443 (+)EnsemblGRCh38hg38GRCh38
GRCh3714102,430,910 - 102,522,780 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,500,734 - 101,586,888 (+)NCBINCBI36Build 36hg18NCBI36
Build 3414101,500,736 - 101,586,887NCBI
Celera1482,485,364 - 82,571,630 (+)NCBICelera
Cytogenetic Map14q32.31NCBI
HuRef1482,609,802 - 82,696,060 (+)NCBIHuRef
CHM1_114102,368,694 - 102,454,973 (+)NCBICHM1_1
T2T-CHM13v2.01496,200,188 - 96,292,054 (+)NCBIT2T-CHM13v2.0
Dync1h1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr86135,436,375 - 135,502,117 (+)NCBIGRCr8
mRatBN7.26129,615,208 - 129,680,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl6129,609,397 - 129,680,883 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx6129,792,251 - 129,857,975 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.06130,088,243 - 130,153,968 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.06129,452,122 - 129,517,762 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06134,958,854 - 135,085,769 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6134,958,854 - 135,085,769 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06144,094,877 - 144,159,980 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46135,318,083 - 135,391,459 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.16135,324,200 - 135,397,646 (+)NCBI
Celera6127,184,881 - 127,250,555 (+)NCBICelera
Cytogenetic Map6q32NCBI
Dync1h1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555381,390,137 - 1,458,025 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555381,388,595 - 1,458,166 (+)NCBIChiLan1.0ChiLan1.0
DYNC1H1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v215103,116,643 - 103,202,954 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan114102,333,470 - 102,419,449 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01482,584,876 - 82,670,750 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.114102,406,807 - 102,489,678 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl14102,406,993 - 102,489,475 (+)Ensemblpanpan1.1panPan2
DYNC1H1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1869,997,021 - 70,064,886 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl869,997,145 - 70,064,825 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha869,511,720 - 69,579,474 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0870,275,463 - 70,343,231 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl870,275,317 - 70,343,231 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1869,939,596 - 70,007,343 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0870,005,661 - 70,073,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0870,405,277 - 70,473,042 (+)NCBIUU_Cfam_GSD_1.0
Dync1h1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244086403,905,752 - 3,970,028 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936835225,324 - 289,954 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936835225,879 - 290,160 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNC1H1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa10.27129,791,255 - 129,832,564 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNC1H1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12479,915,719 - 80,008,666 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2479,915,889 - 80,000,099 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605367,092,529 - 67,183,574 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dync1h1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247342,254,085 - 2,311,177 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247342,253,931 - 2,311,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dync1h1
2286 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1169
Count of miRNA genes:552
Interacting mature miRNAs:667
Transcripts:ENSMUST00000018851, ENSMUST00000107660, ENSMUST00000166185, ENSMUST00000166323, ENSMUST00000167395, ENSMUST00000170024, ENSMUST00000171535, ENSMUST00000172218
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226793Feml10_mfemur length 10, 5 week (mouse)1268346774113363620Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277512220111512220Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80956708113383533Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80956708113383533Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80956708113383533Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280956708113383533Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1280989143114989143Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282666396116666396Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283532075117532224Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283532075117532224Mouse
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285961579119961683Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286396075114831653Mouse
4142007Chlq17_mcirculating hormone level QTL 17 (mouse)Not determined1288052874120092757Mouse
1300545Lifespan3_mlife span 3 (mouse)Not determined1288052874120092757Mouse
1301308Prdt4_mprion disease incubation time 4 (mouse)Not determined1288308354120092757Mouse
5491194Mobq3_mmultigenic obesity QTL 3 (mouse)Not determined1289664071120092757Mouse
1301836Heal5_mwound healing/regeneration 5 (mouse)Not determined1289939031120092757Mouse
1301922Bbaa6_mB.burgdorferi-associated arthritis 6 (mouse)Not determined1290308268120092757Mouse
10402491Dipa4_mdrug induced psychomotor activation 4 (mouse)Not determined1291222515120092757Mouse
12910532Nrq10a_mnoise-induced hearing loss resistant QTL 10a (mouse)1292750025120092757Mouse
12910533Nrq10_mnoise-induced hearing loss resistant QTL 10 (mouse)1292750025120092757Mouse
1357463Vtbt14_mvertebral trabecular bone trait 14 (mouse)Not determined1292936097120092757Mouse
1300973Abmm_mantibody mediated myocarditis (mouse)Not determined1293264461120092757Mouse
11039526Ccc1_mcolitis susceptibility in the Collaborative Cross 1 (mouse)1293528334111028223Mouse
1302177Dps2_mdelta power in slow-wave sleep 2 (mouse)Not determined1294146064120092757Mouse
1302138Im6_mimmunoregulatory 6 (mouse)Not determined1296860337120092757Mouse
1301269Sluc12_msusceptibility to lung cancer 12 (mouse)Not determined1296860337120092757Mouse
10412075Nils1_mneointima lesion size 1 (mouse)Not determined12102024665120092757Mouse
4141297Plyid_mPolymeric IgA dominance (mouse)Not determined109183385115885122Mouse
1558957Igan4_mIgA nephropathy 4 (mouse)Not determined12109750025119024949Mouse

Markers in Region
Dync1h1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv3712111,904,601 - 111,905,109UniSTSGRCm37
MGSCv3712111,877,122 - 111,878,041UniSTSGRCm37
Celera12111,856,623 - 111,857,131UniSTS
Celera12111,829,319 - 111,830,238UniSTS
Cytogenetic Map12F1UniSTS
cM Map1255.0UniSTS
cM Map1255.0UniSTS
AI894280  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812110,666,653 - 110,666,790UniSTSGRCm38
MGSCv3712111,904,863 - 111,905,000UniSTSGRCm37
Celera12111,856,885 - 111,857,022UniSTS
Cytogenetic Map12F1UniSTS
cM Map1255.0UniSTS
Whitehead/MRC_RH121039.09UniSTS
Dync1h1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812110,666,391 - 110,666,899UniSTSGRCm38
MGSCv3712111,904,601 - 111,905,109UniSTSGRCm37
Celera12111,856,623 - 111,857,131UniSTS
Cytogenetic Map12F1UniSTS
Dync1h1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3812110,638,912 - 110,639,831UniSTSGRCm38
MGSCv3712111,877,122 - 111,878,041UniSTSGRCm37
Celera12111,829,319 - 111,830,238UniSTS
Cytogenetic Map12F1UniSTS
cM Map1255.0UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000018851   ⟹   ENSMUSP00000018851
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,567,886 - 110,633,379 (+)Ensembl
GRCm38.p6 Ensembl12110,601,452 - 110,666,945 (+)Ensembl
RefSeq Acc Id: ENSMUST00000107660
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,625,526 - 110,626,278 (+)Ensembl
GRCm38.p6 Ensembl12110,659,092 - 110,659,844 (+)Ensembl
RefSeq Acc Id: ENSMUST00000166185
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,622,839 - 110,623,777 (+)Ensembl
GRCm38.p6 Ensembl12110,656,405 - 110,657,343 (+)Ensembl
RefSeq Acc Id: ENSMUST00000166323
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,629,623 - 110,631,308 (+)Ensembl
GRCm38.p6 Ensembl12110,663,189 - 110,664,874 (+)Ensembl
RefSeq Acc Id: ENSMUST00000167395   ⟹   ENSMUSP00000126117
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,620,596 - 110,624,601 (+)Ensembl
GRCm38.p6 Ensembl12110,654,162 - 110,658,167 (+)Ensembl
RefSeq Acc Id: ENSMUST00000170024
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,627,368 - 110,627,935 (+)Ensembl
GRCm38.p6 Ensembl12110,660,934 - 110,661,501 (+)Ensembl
RefSeq Acc Id: ENSMUST00000171535
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,627,026 - 110,627,904 (+)Ensembl
GRCm38.p6 Ensembl12110,660,592 - 110,661,470 (+)Ensembl
RefSeq Acc Id: ENSMUST00000172218
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl12110,606,958 - 110,607,970 (+)Ensembl
GRCm38.p6 Ensembl12110,640,524 - 110,641,536 (+)Ensembl
RefSeq Acc Id: NM_030238   ⟹   NP_084514
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3912110,567,829 - 110,633,378 (+)NCBI
GRCm3812110,601,395 - 110,666,944 (+)ENTREZGENE
MGSCv3712111,839,605 - 111,905,154 (+)RGD
Celera12111,791,744 - 111,857,176 (+)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_084514   ⟸   NM_030238
- UniProtKB: E9QM71 (UniProtKB/Swiss-Prot),   Q9JHU4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000126117   ⟸   ENSMUST00000167395
RefSeq Acc Id: ENSMUSP00000018851   ⟸   ENSMUST00000018851
Promoters
RGD ID:8679284
Promoter ID:EPDNEW_M17673
Type:initiation region
Name:Dync1h1_1
Description:Mus musculus dynein cytoplasmic 1 heavy chain 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm3812110,601,471 - 110,601,531EPDNEW
RGD ID:6822860
Promoter ID:MM_KWN:12792
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_030238
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,839,641 - 111,840,141 (+)MPROMDB
RGD ID:6846965
Promoter ID:MM_ACW:12061
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:DYNC1H1.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,867,809 - 111,868,309 (+)MPROMDB
RGD ID:6846967
Promoter ID:MM_ACW:12062
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Kidney,   Lung,   Spleen
Transcripts:DYNC1H1.GSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,878,019 - 111,878,519 (+)MPROMDB
RGD ID:6846966
Promoter ID:MM_ACW:12064
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:DYNC1H1.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,892,271 - 111,892,771 (+)MPROMDB
RGD ID:6846963
Promoter ID:MM_ACW:12065
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:DYNC1H1.BSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,893,746 - 111,894,902 (+)MPROMDB
RGD ID:6846970
Promoter ID:MM_ACW:12066
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Liver,   Lung
Transcripts:DYNC1H1.DSEP07,   DYNC1H1.JSEP07,   DYNC1H1.LSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,896,326 - 111,897,487 (+)MPROMDB
RGD ID:6846969
Promoter ID:MM_ACW:12067
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Liver,   Spleen
Transcripts:DYNC1H1.ISEP07,   DYNC1H1.KSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,899,034 - 111,899,534 (+)MPROMDB
RGD ID:6846968
Promoter ID:MM_ACW:12068
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   Kidney,   Lung,   Spleen
Transcripts:DYNC1H1.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv3612111,900,886 - 111,901,387 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:103147 AgrOrtholog
Ensembl Genes ENSMUSG00000018707 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000018851 ENTREZGENE
  ENSMUST00000018851.14 UniProtKB/Swiss-Prot
  ENSMUST00000167395.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.2620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.472.130 UniProtKB/Swiss-Prot
  1.10.8.1220 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.8.720 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.1270.280 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.140.100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.58.1120 UniProtKB/Swiss-Prot
  1.20.920.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.920.60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.490.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.20.180.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  6.10.140.1060 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA1S UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA5_ext UniProtKB/Swiss-Prot
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_C_barrel UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_HC_stalk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_chain_D4_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_D6_P-loop UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy_dom-1 UniProtKB/Swiss-Prot
  Dynein_heavy_dom-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:13424 UniProtKB/Swiss-Prot
MGD MGI:103147 ENTREZGENE
NCBI Gene 13424 ENTREZGENE
PANTHER DYNEIN HEAVY CHAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DYNEIN HEAVY CHAIN, CYTOPLASMIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AAA_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_7 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AAA_lid_11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DHC_N1 UniProtKB/Swiss-Prot
  DHC_N2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_AAA_lid UniProtKB/Swiss-Prot
  Dynein_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynein_heavy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PF12777 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dync1h1 PhenoGen
SMART AAA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DYHC1_MOUSE UniProtKB/Swiss-Prot
  E9QM71 ENTREZGENE
  F6ZX84_MOUSE UniProtKB/TrEMBL
  O08821_MOUSE UniProtKB/TrEMBL
  Q3TAZ3_MOUSE UniProtKB/TrEMBL
  Q3UA73_MOUSE UniProtKB/TrEMBL
  Q80U36_MOUSE UniProtKB/TrEMBL
  Q8C6T5_MOUSE UniProtKB/TrEMBL
  Q923F5_MOUSE UniProtKB/TrEMBL
  Q9JHU4 ENTREZGENE
UniProt Secondary E9QM71 UniProtKB/Swiss-Prot