Gene: Serpine1 (serine (or cysteine) peptidase inhibitor, clade E, member 1)  Mus musculus
Symbol: Serpine1
Name: serine (or cysteine) peptidase inhibitor, clade E, member 1
Description: ENCODES a protein that exhibits serine-type endopeptidase inhibitor activity; protease binding (ortholog); INVOLVED IN defense response to Gram-negative bacterium; negative regulation of endopeptidase activity; negative regulation of plasminogen activation; PARTICIPATES IN hypoxia inducible factor pathway; oxygen homeostasis pathway; coagulation cascade pathway; ASSOCIATED WITH abnormal acute inflammation; abnormal blood circulation; abnormal body weight; ASSOCIATED WITH Hyaline Membrane Disease; Pneumonia, Bacterial; Aortic Aneurysm, Abdominal (ortholog); FOUND IN extracellular matrix (ortholog); extracellular region (ortholog); extracellular space (ortholog); INTERACTS WITH (R)-adrenaline; (R)-noradrenaline; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endothelial plasminogen activator inhibitor; nexin, plasminogen activator inhibitor type 1; PAI; PAI-1; PAI1; Planh1; plasminogen activator inhibitor 1; plasminogen activator inhibitor, type I; Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI); serine (or cysteine) proteinase inhibitor, clade E, member 1; serpin E1
Orthologs: Homo sapiens : SERPINE1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1)  HGNC
Rattus norvegicus : Serpine1 (serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm385137,061,504 - 137,072,272-NCBI
Mouse cM Map5 -NCBI
Mouse Celera Assembly5134,078,340 - 134,089,224-NCBI
Mouse Genome Assembly Build 375137,537,374 - 137,548,142-NCBI
Mouse Genome Assembly Build 36.15137,537,378 - 137,548,129-NCBI
Mouse Cytogenetic Map5 G2 NCBI
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RGD Object Information
RGD ID: 11055
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2013-05-14
Status: ACTIVE



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