(-)-epigallocatechin 3-gallate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 (20S)-20-hydroxypregn-4-en-3-one multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone and [AKR1C3 protein results in increased reduction of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:19010312 and PMID:20036328 (20S)-20-hydroxypregn-4-en-3-one increases chemical synthesis ISO Akr1c3 (Rattus norvegicus) 6480464 AKR1C18 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:8172618 (20S)-20-hydroxypregn-4-en-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:25463305 (E)-cinnamyl alcohol increases expression ISO AKR1C3 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 (S)-naringenin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 naringenin results in decreased activity of AKR1C3 protein CTD PMID:19007764 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19414516 1,10-phenanthroline decreases activity ISO AKR1C3 (Homo sapiens) 6480464 1 and 10-phenanthroline results in decreased activity of AKR1C3 protein CTD PMID:12604236 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of AKR1C18 mRNA CTD PMID:28960355 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of AKR1C18 mRNA CTD PMID:22206623 1,8-Dinitropyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1 and 8-dinitropyrene] which results in increased abundance of 1-amino-8-nitropyrene CTD PMID:36399404 1-Aminopyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1-nitropyrene] which results in increased abundance of 1-aminopyrene CTD PMID:36399404 1-chloro-2,4-dinitrobenzene increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dinitrochlorobenzene results in increased expression of AKR1C3 mRNA CTD PMID:20566472 1-chloro-2,4-dinitrobenzene affects expression EXP 6480464 Dinitrochlorobenzene affects the expression of AKR1C18 mRNA CTD PMID:22302311 1-naphthyl isothiocyanate decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in decreased expression of AKR1C3 mRNA CTD PMID:25380136 and PMID:30723492 1-nitropyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased degradation of 1-nitropyrene] which results in increased abundance of 1-aminopyrene CTD PMID:36399404 11-deoxycorticosterone increases metabolic processing EXP 6480464 AKR1C18 protein results in increased metabolism of Desoxycorticosterone CTD PMID:17122075 13-dihydrodaunorubicin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Daunorubicin] which results in increased abundance of daunorubicinol more ... CTD PMID:30703376 more ... 13-dihydrodaunorubicin increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of daunorubicinol CTD PMID:33025066 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12 and 14)-prostaglandin J2 CTD PMID:19997560 17beta-estradiol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of Estradiol more ... CTD PMID:19010312 more ... 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of AKR1C18 mRNA CTD PMID:19484750 17beta-estradiol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Estradiol results in decreased expression of AKR1C3 mRNA CTD PMID:19619570 more ... 17beta-hydroxy-5alpha-androstan-3-one multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Dihydrotestosterone and Flufenamic Acid inhibits the reaction [AKR1C3 protein results in increased metabolism of Dihydrotestosterone] CTD PMID:14672942 and PMID:19010312 17beta-hydroxy-5alpha-androstan-3-one increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Dihydrotestosterone CTD PMID:14672942 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of AKR1C3 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of AKR1C18 mRNA CTD PMID:28922406 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA] CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of AKR1C18 mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Tetrachlorodibenzodioxin results in decreased expression of AKR1C3 mRNA CTD PMID:19619570 2-amino-14,16-dimethyloctadecan-3-ol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of AKR1C3 protein CTD PMID:32044396 2-hydroxyethyl methacrylate increases expression ISO AKR1C3 (Homo sapiens) 6480464 hydroxyethyl methacrylate results in increased expression of AKR1C3 mRNA CTD PMID:30497689 2-hydroxypropanoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Lactic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 2-methoxyethanol multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] CTD PMID:21427058 2-methoxyethanol decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 methyl cellosolve results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 20-hydroxypregn-4-en-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 3-hydroxypregn-4-en-20-one CTD PMID:25463305 3,3',5-triiodo-L-thyronine increases expression ISO AKR1C3 (Homo sapiens) 6480464 Triiodothyronine results in increased expression of AKR1C3 mRNA CTD PMID:15507505 3,4-dichloroaniline increases expression ISO AKR1C3 (Homo sapiens) 6480464 3 and 4-dichloroaniline results in increased expression of AKR1C3 mRNA CTD PMID:24172598 3,4-methylenedioxymethamphetamine decreases expression EXP 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of AKR1C18 mRNA CTD PMID:20188158 3-chloropropane-1,2-diol decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in decreased expression of AKR1C3 protein CTD PMID:34915118 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA CTD PMID:28628672 3-Nitrobenzanthrone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of 3-aminobenzanthrone and [AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone] which results in increased chemical synthesis of N-hydroxy-3-aminobenzanthrone CTD PMID:30406992 3-Nitrobenzanthrone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of 3-nitrobenzanthrone CTD PMID:30406992 3alpha-hydroxy-5beta-pregnan-20-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of Pregnanolone CTD PMID:25463305 4,4'-diaminodiphenylmethane decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of AKR1C3 mRNA CTD PMID:25380136 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of AKR1C18 mRNA CTD PMID:18648102 4-hydroxybenzoic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 4-hydroxybenzoic acid analog results in decreased activity of AKR1C3 protein CTD PMID:27163852 4-hydroxynon-2-enal multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] CTD PMID:22964423 4-hydroxynon-2-enal increases expression ISO AKR1C3 (Homo sapiens) 6480464 4-hydroxy-2-nonenal results in increased expression of AKR1C3 mRNA and 4-hydroxy-2-nonenal results in increased expression of AKR1C3 protein CTD PMID:22964423 and PMID:30849339 4-hydroxynon-2-enal increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal CTD PMID:22964423 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of AKR1C3 mRNA CTD PMID:28973697 5-fluorouracil affects expression ISO AKR1C3 (Homo sapiens) 6480464 Fluorouracil affects the expression of AKR1C3 mRNA CTD PMID:16584549 5-fluorouracil affects response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 5alpha-Pregnan-20alpha-ol-3-one increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of allopregnan-20 alpha-ol-3-one CTD PMID:25463305 5alpha-pregnane-3,20-dione increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of 5-alpha-Dihydroprogesterone CTD PMID:25463305 6-propyl-2-thiouracil increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of AKR1C18 mRNA CTD PMID:24780913 7-hydroxyflavone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxyflavone results in decreased activity of AKR1C3 protein CTD PMID:19007764 9,10-phenanthroquinone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of 9 and 10-phenanthrenequinone CTD PMID:17950253 and PMID:29108775 9,10-phenanthroquinone increases expression ISO AKR1C3 (Homo sapiens) 6480464 9 and 10-phenanthrenequinone results in increased expression of AKR1C3 protein CTD PMID:29108775 9,10-phenanthroquinone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of 9 and 10-phenanthrenequinone CTD PMID:19442656 more ... 9,10-phenanthroquinone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 9 more ... CTD PMID:17950253 more ... 9-cis-retinal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein mutant form results in increased reduction of 9-cis-retinal and AKR1C3 protein results in increased reduction of 9-cis-retinal CTD PMID:21851338 acetylsalicylic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Aspirin results in decreased activity of AKR1C3 protein CTD PMID:19010312 acrolein multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR1C3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR1C3 mRNA CTD PMID:32699268 aldehydo-D-glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA CTD PMID:37567420 all-trans-retinal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Retinaldehyde CTD PMID:23261716 all-trans-retinoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Tretinoin results in increased expression of AKR1C3 mRNA CTD PMID:23724009 and PMID:33167477 all-trans-retinoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Tretinoin results in decreased activity of AKR1C3 protein] which results in increased susceptibility to Daunorubicin more ... CTD PMID:32588086 Aloe emodin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 aloe emodin results in decreased activity of AKR1C3 protein CTD PMID:35065925 alpha-hexylcinnamaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 hexyl cinnamic aldehyde results in increased expression of AKR1C3 mRNA CTD PMID:20566472 alpha-hexylcinnamaldehyde affects expression EXP 6480464 hexyl cinnamic aldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 alpha-pinene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR1C3 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of AKR1C3 mRNA CTD PMID:32699268 ammonium chloride affects expression ISO Akr1c3 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of AKR1C18 mRNA CTD PMID:16483693 androst-4-ene-3,17-dione increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Androstenedione CTD PMID:19010312 androst-4-ene-3,17-dione increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Androstenedione CTD PMID:17950253 and PMID:20036328 androst-4-ene-3,17-dione multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Dihydrotestosterone more ... CTD PMID:17950253 more ... antimonite multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1C3 mRNA CTD PMID:32076005 antirheumatic drug increases expression ISO AKR1C3 (Homo sapiens) 6480464 Antirheumatic Agents results in increased expression of AKR1C3 mRNA CTD PMID:24449571 arsane multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C3 mRNA CTD PMID:32525701 arsane increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C3 mRNA CTD PMID:36861143 arsenic atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C3 mRNA CTD PMID:32525701 arsenic atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic results in increased expression of AKR1C3 mRNA CTD PMID:36861143 arsenite(3-) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of AKR1C3 mRNA CTD PMID:32076005 arsenous acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C3 mRNA CTD PMID:19128835 more ... arsenous acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] CTD PMID:26598702 arsenous acid decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 atrazine decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 avobenzone increases expression ISO AKR1C3 (Homo sapiens) 6480464 avobenzone results in increased expression of AKR1C3 mRNA CTD PMID:31016361 Bandrowski's base increases expression ISO AKR1C3 (Homo sapiens) 6480464 Bandrowski's base results in increased expression of AKR1C3 mRNA CTD PMID:20566472 benzbromarone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Benzbromarone results in decreased activity of AKR1C3 protein CTD PMID:12604236 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of AKR1C18 mRNA CTD PMID:22228805 benzo[a]pyrene decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of AKR1C3 mRNA CTD PMID:30439556 benzo[a]pyrene increases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of AKR1C3 mRNA and Benzo(a)pyrene results in increased expression of AKR1C3 protein CTD PMID:20106945 more ... benzo[a]pyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA more ... CTD PMID:17612574 and PMID:30439556 Benzo[a]pyrene-7,8-diol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 and 8-dihydrodiol CTD PMID:21910479 benzo[a]pyrene-7,8-dione multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased reduction of and affects the activity of benzo(a)pyrene-7 and 8-dione CTD PMID:21910479 benzo[e]pyrene increases methylation ISO AKR1C3 (Homo sapiens) 6480464 benzo(e)pyrene results in increased methylation of AKR1C3 intron CTD PMID:30157460 benzoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Benzoic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 beta-naphthoflavone increases expression ISO AKR1C3 (Homo sapiens) 6480464 beta-Naphthoflavone results in increased expression of AKR1C3 mRNA CTD PMID:19737606 and PMID:32151702 beta-naphthoflavone multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA CTD PMID:18164116 bexarotene increases expression ISO AKR1C3 (Homo sapiens) 6480464 bexarotene results in increased expression of AKR1C3 mRNA CTD PMID:17178900 bisphenol A decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of AKR1C3 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO AKR1C3 (Homo sapiens) 6480464 bisphenol A results in increased methylation of AKR1C3 gene CTD PMID:31601247 bisphenol A increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of AKR1C3 mRNA CTD PMID:32145629 bisphenol A affects expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol A affects the expression of AKR1C3 mRNA CTD PMID:30903817 Bisphenol B increases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol B results in increased expression of AKR1C3 protein CTD PMID:34186270 bisphenol F increases expression ISO AKR1C3 (Homo sapiens) 6480464 bisphenol F results in increased expression of AKR1C3 protein CTD PMID:34186270 bortezomib increases expression ISO AKR1C3 (Homo sapiens) 6480464 Bortezomib results in increased expression of AKR1C3 mRNA CTD PMID:21215737 Bromazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Bromazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 bromocriptine multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 methyl cellosolve inhibits the reaction [Bromocriptine results in increased expression of AKR1C3 mRNA] CTD PMID:21427058 bromocriptine increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Bromocriptine results in increased expression of AKR1C3 mRNA CTD PMID:21427058 butan-1-ol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of AKR1C3 mRNA CTD PMID:29432896 butyric acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Butyric Acid co-treated with Benzo(a)pyrene] results in increased expression of AKR1C3 mRNA more ... CTD PMID:30439556 butyric acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Butyric Acid results in increased expression of AKR1C3 mRNA CTD PMID:30439556 cadmium atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cadmium results in increased expression of AKR1C3 mRNA CTD PMID:21120746 cadmium atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C3 mRNA CTD PMID:29741670 more ... cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of AKR1C18 mRNA CTD PMID:24067728 cadmium dichloride multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of AKR1C3 mRNA CTD PMID:29741670 more ... capecitabine increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased susceptibility to Capecitabine CTD PMID:16734730 carbamazepine affects expression ISO AKR1C3 (Homo sapiens) 6480464 Carbamazepine affects the expression of AKR1C3 mRNA CTD PMID:25979313 carbon nanotube decreases expression EXP 6480464 Nanotubes and Carbon results in decreased expression of AKR1C18 mRNA CTD PMID:25620056 CGP 52608 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 CGP 52608 promotes the reaction [RORA protein binds to AKR1C3 gene] CTD PMID:28238834 choline multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AKR1C18 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1C18 mRNA CTD PMID:20938992 and PMID:29127188 cinnamyl alcohol increases expression ISO AKR1C3 (Homo sapiens) 6480464 cinnamyl alcohol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 cisplatin increases expression ISO AKR1C3 (Homo sapiens) 6480464 Cisplatin results in increased expression of AKR1C3 mRNA and Cisplatin results in increased expression of AKR1C3 protein CTD PMID:23165153 and PMID:27392435 cisplatin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of AKR1C3 mRNA more ... CTD PMID:23165153 and PMID:27392435 cisplatin decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Cisplatin CTD PMID:23165153 Clofop increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of fenofibric acid CTD PMID:27599626 cloxazolam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 cloxazolam results in decreased activity of AKR1C3 protein CTD PMID:11995921 and PMID:12604236 cobalt dichloride decreases expression ISO AKR1C3 (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of AKR1C3 mRNA CTD PMID:17553155 colforsin daropate hydrochloride decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Colforsin results in decreased expression of AKR1C3 mRNA CTD PMID:28235592 coniferyl aldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 coniferaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:26275128 copper atom multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA CTD PMID:20971185 copper(0) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of AKR1C3 mRNA CTD PMID:20971185 copper(II) sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of AKR1C3 mRNA CTD PMID:19549813 crotonaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 2-butenal results in increased expression of AKR1C3 mRNA CTD PMID:20471460 cycloheximide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] CTD PMID:21787718 cyclopentanol increases oxidation ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased oxidation of cyclopentanol CTD PMID:23261716 cyclopentanone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of cyclopentanone CTD PMID:23261716 cyclopentanone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased reduction of cyclopentanone more ... CTD PMID:23261716 cyclosporin A decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of AKR1C18 mRNA CTD PMID:21865292 cyclosporin A decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of AKR1C3 mRNA CTD PMID:25562108 and PMID:33631201 D-glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA CTD PMID:37567420 daunorubicin increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Daunorubicin and AKR1C3 results in increased metabolism of Daunorubicin CTD PMID:20837989 more ... daunorubicin increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Daunorubicin CTD PMID:33025066 and PMID:35972551 daunorubicin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Daunorubicin] which results in increased abundance of daunorubicinol more ... CTD PMID:29992508 more ... daunorubicin decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Daunorubicin CTD PMID:29992508 more ... deguelin increases expression ISO AKR1C3 (Homo sapiens) 6480464 deguelin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 dehydroepiandrosterone affects metabolic processing ISO Akr1c3 (Rattus norvegicus) 6480464 AKR1C18 protein affects the metabolism of Dehydroepiandrosterone CTD PMID:15261307 desogestrel decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Desogestrel results in decreased activity of AKR1C3 protein CTD PMID:21182831 dexamethasone increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dexamethasone results in increased expression of AKR1C3 mRNA CTD PMID:25047013 dexamethasone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA CTD PMID:28628672 dextran sulfate multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 mRNA CTD PMID:29950665 diarsenic trioxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide results in increased expression of AKR1C3 mRNA CTD PMID:19128835 more ... diarsenic trioxide decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Arsenic Trioxide CTD PMID:20707922 diarsenic trioxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to AKR1C3 protein] CTD PMID:26598702 diazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Diazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 and PMID:12604236 dibenzo[a,l]pyrene multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Particulate Matter co-treated with dibenzo(a more ... CTD PMID:17612574 dibutyl phthalate increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of AKR1C18 mRNA CTD PMID:21266533 dicrotophos decreases expression ISO AKR1C3 (Homo sapiens) 6480464 dicrotophos results in decreased expression of AKR1C3 mRNA CTD PMID:28302478 diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of AKR1C3 mRNA CTD PMID:19665456 diethylstilbestrol multiple interactions EXP 6480464 sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] CTD PMID:19665456 dioxygen multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of and affects the activity of benzo(a)pyrene-3 and 6-quinone] which results in decreased abundance of Oxygen CTD PMID:21910479 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA and Antimony Potassium Tartrate results in increased expression of AKR1C3 protein CTD PMID:28713220 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1C3 mRNA CTD PMID:32076005 disulfiram increases expression ISO AKR1C3 (Homo sapiens) 6480464 Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 diuron increases expression ISO AKR1C3 (Homo sapiens) 6480464 Diuron metabolite results in increased expression of AKR1C3 mRNA CTD PMID:24172598 dorsomorphin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxifluridine increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased susceptibility to doxifluridine CTD PMID:16734730 doxorubicin affects reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the reduction of Doxorubicin CTD PMID:18635746 doxorubicin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of AKR1C3 mRNA CTD PMID:29803840 doxorubicin increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 results in increased metabolism of Doxorubicin CTD PMID:20837989 dutasteride increases expression ISO AKR1C3 (Homo sapiens) 6480464 Dutasteride results in increased expression of AKR1C3 mRNA CTD PMID:16806904 dydrogesterone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Dydrogesterone results in decreased activity of AKR1C3 protein CTD PMID:21182831 dydrogesterone decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Dydrogesterone results in decreased expression of AKR1C3 mRNA CTD PMID:23183084 emodin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Emodin results in decreased activity of AKR1C3 protein CTD PMID:35065925 enasidenib multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 enasidenib inhibits the reaction [[AKR1C3 protein results in increased reduction of Daunorubicin] which results in increased abundance of daunorubicinol] more ... CTD PMID:35972551 enasidenib decreases activity ISO AKR1C3 (Homo sapiens) 6480464 enasidenib results in decreased activity of AKR1C3 protein CTD PMID:35972551 estazolam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Estazolam results in decreased activity of AKR1C3 protein CTD PMID:11995921 estrone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Estrone CTD PMID:19010312 estrone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Estrone CTD PMID:20036328 estrone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Estrone] which results in increased chemical synthesis of Estradiol and [AKR1C3 protein results in increased reduction of Estrone] which results in increased chemical synthesis of Estradiol CTD PMID:19010312 and PMID:20036328 ethanol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of AKR1C3 mRNA CTD PMID:29432896 ethylparaben increases expression ISO AKR1C3 (Homo sapiens) 6480464 ethyl-p-hydroxybenzoate results in increased expression of AKR1C3 mRNA CTD PMID:37690743 eugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 Eugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 farnesal increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of farnesal CTD PMID:21187079 farnesoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid and [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid CTD PMID:21187079 farnesol increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of Farnesol CTD PMID:21187079 farnesol multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol and [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol CTD PMID:21187079 fenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 fenamic acid analog results in decreased activity of AKR1C3 protein CTD PMID:19010312 flufenamic acid affects binding ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid binds to AKR1C3 protein CTD PMID:14996743 flufenamic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] and Flufenamic Acid inhibits the reaction [AKR1C3 protein results in increased metabolism of Dihydrotestosterone] CTD PMID:14672942 and PMID:23933386 flufenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flufenamic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 flunitrazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flunitrazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 flurbiprofen multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid and [Flurbiprofen results in decreased activity of AKR1C3 protein] which results in increased metabolism of Farnesol CTD PMID:21187079 flurbiprofen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Flurbiprofen results in decreased activity of AKR1C3 protein CTD PMID:19010312 and PMID:21187079 folic acid multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AKR1C18 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1C18 mRNA CTD PMID:20938992 and PMID:29127188 formaldehyde decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of AKR1C3 mRNA CTD PMID:23649840 formaldehyde increases expression ISO AKR1C3 (Homo sapiens) 6480464 Formaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:28937961 Frangulin A decreases activity ISO AKR1C3 (Homo sapiens) 6480464 frangulin A results in decreased activity of AKR1C3 protein CTD PMID:35065925 Frangulin B decreases activity ISO AKR1C3 (Homo sapiens) 6480464 frangulin B results in decreased activity of AKR1C3 protein CTD PMID:35065925 fructose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA CTD PMID:37567420 furan increases expression EXP 6480464 furan results in increased expression of AKR1C18 mRNA CTD PMID:24183702 and PMID:37517673 geranylgeraniol increases chemical synthesis ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased chemical synthesis of geranylgeraniol CTD PMID:21187079 gliclazide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Gliclazide results in decreased activity of AKR1C3 protein CTD PMID:26362498 glimepiride decreases activity ISO AKR1C3 (Homo sapiens) 6480464 glimepiride results in decreased activity of AKR1C3 protein CTD PMID:26362498 glipizide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glipizide results in decreased activity of AKR1C3 protein CTD PMID:26362498 glucose multiple interactions EXP 6480464 [lard co-treated with Cholesterol and Dietary co-treated with Dietary Sucrose co-treated with Fructose co-treated with Glucose] results in decreased expression of AKR1C18 mRNA CTD PMID:37567420 glyburide decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glyburide results in decreased activity of AKR1C3 protein CTD PMID:26362498 glycidyl methacrylate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 glycidyl methacrylate results in decreased expression of AKR1C3 protein CTD PMID:36641056 glycyrrhetinate affects activity ISO AKR1C3 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein CTD PMID:11165023 glycyrrhetinate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 glycyrrhetinic acid affects activity ISO AKR1C3 (Homo sapiens) 6480464 18alpha-glycyrrhetinic acid affects the activity of AKR1C3 protein CTD PMID:11165023 glycyrrhetinic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Glycyrrhetinic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 glyphosate decreases expression EXP 6480464 Glyphosate results in decreased expression of AKR1C18 protein CTD PMID:37208198 gold atom increases expression ISO AKR1C3 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 gold(0) increases expression ISO AKR1C3 (Homo sapiens) 6480464 Gold results in increased expression of AKR1C3 mRNA CTD PMID:29705079 hexane increases expression ISO AKR1C3 (Homo sapiens) 6480464 n-hexane results in increased expression of AKR1C3 mRNA CTD PMID:20566472 hexestrol decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Hexestrol results in decreased activity of AKR1C3 protein CTD PMID:12604236 hydrogen peroxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide] more ... CTD PMID:21910479 and PMID:22964423 hydrogen peroxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of AKR1C3 protein CTD PMID:22964423 hydrogen peroxide increases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide CTD PMID:22964423 ibuprofen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Ibuprofen results in decreased activity of AKR1C3 protein CTD PMID:19010312 indometacin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AKR1C3 mRNA more ... CTD PMID:17950253 and PMID:28628672 indometacin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Indomethacin analog results in decreased activity of AKR1C3 protein and Indomethacin results in decreased activity of AKR1C3 protein CTD PMID:12604236 more ... indometacin affects binding ISO AKR1C3 (Homo sapiens) 6480464 Indomethacin binds to AKR1C3 protein CTD PMID:14996743 inulin multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AKR1C18 mRNA CTD PMID:36331819 isoeugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 Isoxanthohumol decreases activity ISO AKR1C3 (Homo sapiens) 6480464 isoxanthohumol results in decreased activity of AKR1C3 protein CTD PMID:35065925 ivermectin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Ivermectin results in decreased expression of AKR1C3 protein CTD PMID:32959892 L-methionine multiple interactions EXP 6480464 [Choline deficiency co-treated with Folic Acid deficiency co-treated with Methionine deficiency] results in increased expression of AKR1C18 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1C18 mRNA CTD PMID:20938992 and PMID:29127188 levonorgestrel decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Levonorgestrel results in decreased activity of AKR1C3 protein CTD PMID:21182831 lithocholic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Lithocholic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 and PMID:21851338 LY294002 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] CTD PMID:21787718 meclofenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Meclofenamic Acid results in decreased activity of AKR1C3 protein CTD PMID:19010312 more ... Medazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Medazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 and PMID:12604236 medroxyprogesterone acetate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Medroxyprogesterone Acetate inhibits the reaction [[AKR1C3 protein results in increased metabolism of Prostaglandin D2] which results in increased abundance of Dinoprost]] which results in increased abundance of 15-deoxy-delta(12 more ... CTD PMID:19997560 and PMID:23261716 medroxyprogesterone acetate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Medroxyprogesterone Acetate results in decreased activity of AKR1C3 protein CTD PMID:12604236 more ... mefenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Mefenamic Acid analog results in decreased activity of AKR1C3 protein CTD PMID:19010312 mercury dibromide increases expression ISO AKR1C3 (Homo sapiens) 6480464 mercuric bromide results in increased expression of AKR1C3 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA CTD PMID:27188386 methapyrilene increases methylation ISO AKR1C3 (Homo sapiens) 6480464 Methapyrilene results in increased methylation of AKR1C3 intron CTD PMID:30157460 methyl salicylate increases expression ISO AKR1C3 (Homo sapiens) 6480464 methyl salicylate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 methylglyoxal increases expression ISO AKR1C3 (Homo sapiens) 6480464 Pyruvaldehyde results in increased expression of AKR1C3 mRNA CTD PMID:25451587 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of AKR1C18 mRNA CTD PMID:20061341 methylmercury chloride increases expression ISO AKR1C3 (Homo sapiens) 6480464 methylmercuric chloride results in increased expression of AKR1C3 mRNA CTD PMID:28001369 midostaurin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 midostaurin results in decreased activity of AKR1C3 protein CTD PMID:33025066 midostaurin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 midostaurin inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Daunorubicin] and midostaurin inhibits the reaction [AKR1C3 protein results in increased metabolism of Daunorubicin] CTD PMID:33025066 N-acetyl-L-cysteine multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein] and Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA] CTD PMID:18829485 and PMID:21787718 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO AKR1C3 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of AKR1C3 mRNA CTD PMID:21215737 and PMID:23165153 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [tolfenamic acid inhibits the reaction [AKR1C3 protein results in decreased susceptibility to Cisplatin]] CTD PMID:23165153 N-nitrosodiethylamine increases expression EXP 6480464 Diethylnitrosamine results in increased expression of AKR1C18 mRNA CTD PMID:24535843 N-nitrosodiethylamine multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of AKR1C18 mRNA CTD PMID:18164116 N-nitrosomorpholine increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 N-nitrosomorpholine results in increased expression of AKR1C18 protein CTD PMID:19716841 NAD zwitterion multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol more ... CTD PMID:25446855 NAD(+) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NAD] results in increased oxidation of acenaphthene-1-ol more ... CTD PMID:25446855 NADP zwitterion multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:14672942 more ... NADP(+) multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein co-treated with NADP] results in increased oxidation of and affects the activity of benzo(a)pyrene 7 more ... CTD PMID:14672942 more ... naphthalenes multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of and affects the activity of Naphthalenes CTD PMID:21910479 naproxen decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Naproxen results in decreased activity of AKR1C3 protein CTD PMID:19010312 nickel atom decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Nickel results in decreased expression of AKR1C3 mRNA CTD PMID:23195993 nickel sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 nickel sulfate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 nitrazepam decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Nitrazepam results in decreased activity of AKR1C3 protein CTD PMID:11995921 norethisterone decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Norethindrone results in decreased activity of AKR1C3 protein CTD PMID:21182831 ochratoxin A decreases expression ISO AKR1C3 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of AKR1C3 mRNA CTD PMID:19287073 and PMID:32905824 octyl gallate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 octyl gallate results in decreased activity of AKR1C3 protein CTD PMID:27163852 oxaliplatin affects response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein affects the susceptibility to oxaliplatin CTD PMID:23933386 oxaliplatin multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 alpha-methylcinnamic acid inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] more ... CTD PMID:23933386 oxcarbazepine increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of oxcarbazepine CTD PMID:25063510 oxidopamine increases expression ISO AKR1C3 (Homo sapiens) 6480464 Oxidopamine results in increased expression of AKR1C3 mRNA and Oxidopamine results in increased expression of AKR1C3 protein CTD PMID:33486071 oxycodone decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Oxycodone results in decreased expression of AKR1C3 mRNA CTD PMID:23439660 ozone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of AKR1C3 mRNA more ... CTD PMID:32699268 p-chloromercuribenzoic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 p-Chloromercuribenzoic Acid results in increased expression of AKR1C3 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA CTD PMID:27188386 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of AKR1C18 mRNA CTD PMID:17562736 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of AKR1C18 mRNA CTD PMID:29246445 paracetamol multiple interactions EXP 6480464 PANX1 gene mutant form inhibits the reaction [Acetaminophen results in increased expression of AKR1C18 mRNA] CTD PMID:29246445 paracetamol decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Acetaminophen results in decreased expression of AKR1C3 mRNA CTD PMID:21420995 paraquat multiple interactions EXP 6480464 [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA CTD PMID:28012437 perfluorohexanesulfonic acid increases expression EXP 6480464 perfluorohexanesulfonic acid results in increased expression of AKR1C18 mRNA CTD PMID:37315490 and PMID:37995155 perfluorooctane-1-sulfonic acid affects expression EXP 6480464 perfluorooctane sulfonic acid affects the expression of AKR1C18 mRNA and perfluorooctane sulfonic acid affects the expression of AKR1C3 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of AKR1C18 mRNA CTD PMID:36331819 perfluorooctanoic acid affects expression EXP 6480464 perfluorooctanoic acid affects the expression of AKR1C18 mRNA and perfluorooctanoic acid affects the expression of AKR1C3 mRNA CTD PMID:19429403 perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of AKR1C3 mRNA CTD PMID:17681415 perfluorooctanoic acid decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of AKR1C18 mRNA CTD PMID:16221955 and PMID:19162173 phenethyl caffeate decreases activity ISO AKR1C3 (Homo sapiens) 6480464 caffeic acid phenethyl ester results in decreased activity of AKR1C3 protein CTD PMID:27163852 phenobarbital increases expression ISO AKR1C3 (Homo sapiens) 6480464 Phenobarbital results in increased expression of AKR1C3 protein CTD PMID:35881160 phenolphthalein multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 Phenolphthalein inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] CTD PMID:23933386 phenolphthalein decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Phenolphthalein results in decreased activity of AKR1C3 protein CTD PMID:12604236 phenylmercury acetate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of AKR1C3 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA CTD PMID:27188386 phthalaldehyde affects expression EXP 6480464 o-Phthalaldehyde affects the expression of AKR1C18 mRNA CTD PMID:22302311 picoxystrobin increases expression ISO AKR1C3 (Homo sapiens) 6480464 picoxystrobin results in increased expression of AKR1C3 mRNA CTD PMID:33512557 pirinixic acid multiple interactions EXP 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of AKR1C18 mRNA] CTD PMID:17950772 and PMID:20032461 pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of AKR1C18 mRNA CTD PMID:17950772 more ... potassium chromate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 potassium chromate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 potassium chromate(VI) results in decreased expression of AKR1C3 mRNA CTD PMID:22079256 pravastatin decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Pravastatin results in decreased expression of AKR1C3 mRNA CTD PMID:27225895 pravastatin decreases expression EXP 6480464 Pravastatin results in decreased expression of AKR1C18 mRNA CTD PMID:27225895 progesterone affects abundance EXP 6480464 AKR1C18 protein affects the abundance of Progesterone CTD PMID:15471942 progesterone increases metabolic processing ISO Akr1c3 (Rattus norvegicus) 6480464 AKR1C18 protein results in increased metabolism of Progesterone CTD PMID:8172618 progesterone affects metabolic processing ISO Akr1c3 (Rattus norvegicus) 6480464 AKR1C18 protein affects the metabolism of Progesterone CTD PMID:15261307 progesterone increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Progesterone CTD PMID:20036328 and PMID:25463305 progesterone increases expression ISO AKR1C3 (Homo sapiens) 6480464 Progesterone results in increased expression of AKR1C3 mRNA CTD PMID:23183084 progesterone decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Progesterone results in decreased expression of AKR1C3 mRNA CTD PMID:23183084 progesterone increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Progesterone CTD PMID:19010312 progesterone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone and [AKR1C3 protein results in increased reduction of Progesterone] which results in increased chemical synthesis of 20-alpha-Dihydroprogesterone CTD PMID:19010312 and PMID:20036328 progesterone increases metabolic processing EXP 6480464 AKR1C18 protein results in increased metabolism of Progesterone CTD PMID:17122075 progesterone affects metabolic processing EXP 6480464 AKR1C18 protein affects the metabolism of Progesterone CTD PMID:15471942 propan-2-ol increases expression ISO AKR1C3 (Homo sapiens) 6480464 2-Propanol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 prostaglandin D2 increases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased metabolism of Prostaglandin D2 CTD PMID:19010312 prostaglandin D2 decreases metabolic processing ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased metabolism of Prostaglandin D2 CTD PMID:20036328 prostaglandin D2 increases reduction ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in increased reduction of Prostaglandin D2 CTD PMID:20036328 prostaglandin D2 decreases response to substance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 protein results in decreased susceptibility to Prostaglandin D2 CTD PMID:20036328 prostaglandin D2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2 more ... CTD PMID:19997560 and PMID:20036328 prostaglandin F2alpha multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of Prostaglandin D2] which results in increased chemical synthesis of Dinoprost more ... CTD PMID:19997560 and PMID:20036328 prostaglandin J2 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in decreased metabolism of Prostaglandin D2] which results in decreased chemical synthesis of 9-deoxy-delta-9-prostaglandin D2 CTD PMID:20036328 quercetin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Quercetin results in decreased activity of AKR1C3 protein CTD PMID:19007764 rac-lactic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Lactic Acid results in increased expression of AKR1C3 mRNA CTD PMID:20566472 resveratrol multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA CTD PMID:25905778 rotenone decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of AKR1C3 mRNA CTD PMID:28374803 salicylic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Salicylic Acid results in decreased activity of AKR1C3 protein CTD PMID:19010312 SB 431542 multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 silibinin decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Silybin results in decreased activity of AKR1C3 protein CTD PMID:19007764 silicon dioxide decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of AKR1C3 mRNA CTD PMID:25895662 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of AKR1C18 mRNA CTD PMID:29341224 silicon dioxide increases expression ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide results in increased expression of AKR1C3 mRNA CTD PMID:25351596 silicon dioxide increases secretion ISO AKR1C3 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased secretion of AKR1C3 protein CTD PMID:25895662 simvastatin decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Simvastatin results in decreased expression of AKR1C3 mRNA CTD PMID:18192897 sodium arsenate multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of AKR1C3 mRNA CTD PMID:32525701 sodium arsenite increases expression ISO AKR1C3 (Homo sapiens) 6480464 sodium arsenite results in increased expression of AKR1C3 mRNA and sodium arsenite results in increased expression of AKR1C3 protein CTD PMID:12727804 more ... sodium arsenite multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of AKR1C3 mRNA CTD PMID:32076005 sodium arsenite multiple interactions EXP 6480464 sodium arsenite promotes the reaction [Diethylstilbestrol results in increased expression of AKR1C3 mRNA] CTD PMID:19665456 sodium arsenite affects expression EXP 6480464 sodium arsenite affects the expression of AKR1C18 mRNA CTD PMID:16507464 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of AKR1C18 mRNA CTD PMID:17350061 sodium dichromate decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 sodium bichromate results in decreased expression of AKR1C3 mRNA CTD PMID:25993096 sodium dodecyl sulfate increases expression ISO AKR1C3 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in increased expression of AKR1C3 mRNA CTD PMID:20566472 sodium dodecyl sulfate decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Sodium Dodecyl Sulfate results in decreased expression of AKR1C3 mRNA CTD PMID:31734321 sodium dodecyl sulfate decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Sodium Dodecyl Sulfate results in decreased expression of AKR1C18 mRNA CTD PMID:12815608 streptozocin multiple interactions ISO Akr1c3 (Rattus norvegicus) 6480464 [resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA CTD PMID:25905778 streptozocin multiple interactions EXP 6480464 [Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA CTD PMID:29127188 sulforaphane increases expression ISO AKR1C3 (Homo sapiens) 6480464 sulforaphane results in increased expression of AKR1C3 mRNA and sulforaphane results in increased expression of AKR1C3 protein CTD PMID:24383545 and PMID:31746589 sulindac decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Sulindac results in decreased activity of AKR1C3 protein CTD PMID:19010312 sulpiride decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Sulpiride results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 superoxide multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased reduction of 9 more ... CTD PMID:19442656 and PMID:21910479 testosterone increases abundance ISO AKR1C3 (Homo sapiens) 6480464 AKR1C3 promoter SNP results in increased abundance of Testosterone CTD PMID:16263811 testosterone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [AKR1C3 protein results in increased metabolism of Androstenedione] which results in increased chemical synthesis of Testosterone and [AKR1C3 protein results in increased reduction of Androstenedione] which results in increased chemical synthesis of Testosterone CTD PMID:19010312 and PMID:20036328 testosterone enanthate affects expression ISO AKR1C3 (Homo sapiens) 6480464 testosterone enanthate affects the expression of AKR1C3 mRNA CTD PMID:17440010 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of AKR1C18 mRNA CTD PMID:27339419 tetrachloromethane increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of AKR1C3 mRNA CTD PMID:31150632 tetraphene increases expression ISO AKR1C3 (Homo sapiens) 6480464 benz(a)anthracene results in increased expression of AKR1C3 mRNA CTD PMID:22236718 thioacetamide decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of AKR1C18 mRNA and Thioacetamide results in decreased expression of AKR1C3 mRNA CTD PMID:23411599 and PMID:34492290 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of AKR1C18 mRNA CTD PMID:23131501 titanium dioxide multiple interactions EXP 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of AKR1C18 mRNA CTD PMID:29950665 titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of AKR1C18 mRNA CTD PMID:23557971 tolcapone decreases expression ISO Akr1c3 (Rattus norvegicus) 6480464 tolcapone results in decreased expression of AKR1C3 mRNA CTD PMID:24136188 tolfenamic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 tolfenamic acid results in decreased activity of AKR1C3 protein CTD PMID:21187079 and PMID:23165153 tolfenamic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [tolfenamic acid results in decreased activity of AKR1C3 protein] which results in increased chemical synthesis of farnesoic acid more ... CTD PMID:21187079 and PMID:23165153 trans-isoeugenol increases expression ISO AKR1C3 (Homo sapiens) 6480464 isoeugenol results in increased expression of AKR1C3 mRNA CTD PMID:20566472 trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of AKR1C18 mRNA CTD PMID:25549359 trichostatin A increases expression ISO AKR1C3 (Homo sapiens) 6480464 trichostatin A results in increased expression of AKR1C3 mRNA CTD PMID:24935251 and PMID:26705709 triclosan decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Triclosan results in decreased expression of AKR1C3 mRNA CTD PMID:30510588 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of AKR1C18 mRNA CTD PMID:19042947 trimellitic anhydride affects expression EXP 6480464 trimellitic anhydride affects the expression of AKR1C18 mRNA CTD PMID:22302311 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of AKR1C3 mRNA CTD PMID:28973697 umbelliferone increases expression ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin results in increased expression of AKR1C3 mRNA and 7-hydroxycoumarin results in increased expression of AKR1C3 protein CTD PMID:22964423 and PMID:28263721 umbelliferone multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to 4-hydroxy-2-nonenal] and 7-hydroxycoumarin inhibits the reaction [AKR1C3 mutant form results in increased susceptibility to Hydrogen Peroxide] CTD PMID:22964423 uranium atom affects expression ISO AKR1C3 (Homo sapiens) 6480464 Uranium affects the expression of AKR1C3 mRNA CTD PMID:15672453 urethane decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Urethane results in decreased expression of AKR1C3 mRNA CTD PMID:28818685 ursodeoxycholic acid decreases activity ISO AKR1C3 (Homo sapiens) 6480464 Ursodeoxycholic Acid results in decreased activity of AKR1C3 protein CTD PMID:12604236 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of AKR1C18 mRNA CTD PMID:17292431 valproic acid multiple interactions ISO AKR1C3 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of AKR1C3 mRNA CTD PMID:27188386 valproic acid increases expression ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid results in increased expression of AKR1C3 mRNA CTD PMID:23179753 more ... valproic acid decreases methylation ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of AKR1C3 gene CTD PMID:29154799 valproic acid affects expression ISO AKR1C3 (Homo sapiens) 6480464 Valproic Acid affects the expression of AKR1C3 mRNA CTD PMID:25979313 vorinostat increases expression ISO AKR1C3 (Homo sapiens) 6480464 vorinostat results in increased expression of AKR1C3 mRNA CTD PMID:18769122 vorinostat decreases expression ISO AKR1C3 (Homo sapiens) 6480464 vorinostat results in decreased expression of AKR1C3 mRNA CTD PMID:18769122 zaragozic acid A affects expression EXP 6480464 squalestatin 1 affects the expression of AKR1C18 mRNA CTD PMID:27225895 zaragozic acid A increases expression ISO Akr1c3 (Rattus norvegicus) 6480464 squalestatin 1 results in increased expression of AKR1C3 mRNA CTD PMID:27225895 zinc atom decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Zinc deficiency results in decreased expression of AKR1C3 mRNA CTD PMID:22171008 zinc(0) decreases expression ISO AKR1C3 (Homo sapiens) 6480464 Zinc deficiency results in decreased expression of AKR1C3 mRNA CTD PMID:22171008 zomepirac decreases activity ISO AKR1C3 (Homo sapiens) 6480464 zomepirac results in decreased activity of AKR1C3 protein CTD PMID:19010312
