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ONTOLOGY REPORT - ANNOTATIONS

Term:aspartic-type endopeptidase activity
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Accession:GO:0004190 term browser browse the term
Definition:Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
Synonyms:exact_synonym: aspartic endopeptidase activity
 narrow_synonym: aspartate protease activity;   aspartic protease activity;   aspartyl protease activity;   carboxyl protease activity
 xref: EC:3.4.23;   reactome:R-HSA-157353 "NEXT1 is cleaved to produce NICD1";   reactome:R-HSA-157640 "NEXT2 is cleaved to produce NICD2";   reactome:R-HSA-2022403 "Renin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)";   reactome:R-HSA-2022412 "Renin hydrolyzes Angiotensinogen to Angiotensin-(1-10)";   reactome:R-HSA-2065357 "Prorenin:Prorenin Receptor hydrolyzes Angiotensinogen to Angiotensin-(1-10)";   reactome:R-HSA-2220988 "NEXT1 PEST domain mutants are cleaved to produce NICD1 PEST domain mutants";   reactome:R-HSA-373705 "Caspase cleavage of DCC";   reactome:R-HSA-9013361 "NEXT3 is cleaved to produce NICD3";   reactome:R-HSA-9017817 "Gamma-secretase cleaves YBX1:NOTCH3";   reactome:R-HSA-9604294 "Gamma-secretase cleaves NOTCH4"

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aspartic-type endopeptidase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G H AC068580.4 novel protein enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 Ensembl chr11:1,734,821...1,763,954 JBrowse link
G N Asprv1 aspartic peptidase retroviral like 1 enables ISO (MGI:3694389|PMID:16837463)
(PMID:16098038)		 UniProt PMID:16098038 PMID:16837463 MGI:3694389 NCBI chrNW_004624762:3,438,813...3,445,688 JBrowse link
G G ASPRV1 aspartic peptidase retroviral like 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr14:37,019,454...37,051,341
Ensembl chr14:37,158,086...37,159,117
Ensembl chr14:37,158,086...37,159,117 		JBrowse link
G P ASPRV1 aspartic peptidase retroviral like 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:72,323,958...72,536,564
Ensembl chr 3:72,493,129...72,493,908 		JBrowse link
G S Asprv1 aspartic peptidase retroviral like 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936491:14,170,232...14,171,830
Ensembl chrNW_004936491:14,170,793...14,171,830 		JBrowse link
G D ASPRV1 aspartic peptidase retroviral like 1 enables IEA InterPro GO_REF:0000002 NCBI chr10:68,586,405...68,589,753
Ensembl chr10:68,586,975...68,589,287 		JBrowse link
G B ASPRV1 aspartic peptidase retroviral like 1 enables IEA InterPro GO_REF:0000002 NCBI chr2A:70,008,862...70,198,244
Ensembl chr2A:71,120,541...71,121,572 		JBrowse link
G C Asprv1 aspartic peptidase retroviral like 1 enables ISO (PMID:16098038)
(MGI:3694389|PMID:16837463)		 UniProt PMID:16098038 PMID:16837463 MGI:3694389 NCBI chrNW_004955424:15,190,746...15,193,270 JBrowse link
G R Asprv1 aspartic peptidase, retroviral-like 1 enables ISO (PMID:16098038)
(MGI:3694389|PMID:16837463)		 RGD PMID:16098038 PMID:16837463 MGI:3694389 NCBI chr 4:119,077,415...119,078,887
Ensembl chr 4:119,077,356...119,078,379 		JBrowse link
G M Asprv1 aspartic peptidase, retroviral-like 1 enables IDA
ISO		 (MGI:3694389|PMID:16837463) UniProt
MGI		 PMID:16837463 GO_REF:0000119 MGI:3694389 MGI:4834177 NCBI chr 6:86,605,216...86,606,692
Ensembl chr 6:86,605,146...86,606,692 		JBrowse link
G H ASPRV1 aspartic peptidase retroviral like 1 enables IDA
IEA		 (PMID:16098038) UniProt
InterPro		 PMID:16098038 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:69,932,717...70,087,375
Ensembl chr 2:69,960,089...69,961,631 		JBrowse link
G N Bace1 beta-secretase 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chrNW_004624784:12,725,419...12,759,530
Ensembl chrNW_004624784:12,725,063...12,759,637 		JBrowse link
G G BACE1 beta-secretase 1 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:108,659,723...108,689,879
Ensembl chr 1:108,657,584...108,689,843 		JBrowse link
G P BACE1 beta-secretase 1 enables IEA UniProt
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr 9:44,640,389...44,665,863
Ensembl chr 9:44,640,394...44,665,835 		JBrowse link
G S Bace1 beta-secretase 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chrNW_004936542:2,514,297...2,539,088
Ensembl chrNW_004936542:2,514,300...2,539,135 		JBrowse link
G D BACE1 beta-secretase 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr 5:16,308,953...16,319,100
Ensembl chr 5:16,308,944...16,319,100 		JBrowse link
G B BACE1 beta-secretase 1 enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr11:112,120,950...112,151,505
Ensembl chr11:116,054,303...116,084,812 		JBrowse link
G C Bace1 beta-secretase 1 enables ISO (PMID:10531052)
(PMID:25592972)
(MGI:6316502|PMID:29325091)		 UniProt
MGI		 PMID:10531052 PMID:25592972 PMID:29325091 MGI:6316502 NCBI chrNW_004955412:18,596,643...18,620,089
Ensembl chrNW_004955412:18,596,643...18,620,362 		JBrowse link
G R Bace1 beta-secretase 1 enables ISS
ISO
IEA		 GO_REF:0000024
(MGI:6316502|PMID:29325091), (PMID:25592972)
GO_REF:0000043
(PMID:10531052)		 UniProt
RGD		 PMID:10531052 PMID:25592972 PMID:29325091 GO_REF:0000024 GO_REF:0000043 MGI:6316502 NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G M Bace1 beta-site APP cleaving enzyme 1 enables IMP
IDA
ISO		 (MGI:6316502|PMID:29325091)
(PMID:25592972)		 UniProt
MGI		 PMID:25592972 PMID:29325091 GO_REF:0000119 MGI:4834177 MGI:6316502 NCBI chr 9:45,749,878...45,775,694
Ensembl chr 9:45,749,878...45,775,697 		JBrowse link
G H BACE1 beta-secretase 1 enables IEA
IDA		 (PMID:10531052) Ensembl
UniProt
InterPro		 PMID:10531052 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259 		JBrowse link
G N Bace2 beta-secretase 2 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chrNW_004624745:28,690,045...28,765,506
Ensembl chrNW_004624745:28,690,149...28,765,588 		JBrowse link
G G BACE2 beta-secretase 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr 2:85,079,404...85,194,908
Ensembl chr 2:85,079,812...85,187,944 		JBrowse link
G P BACE2 beta-secretase 2 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 NCBI chr13:204,600,740...204,720,215
Ensembl chr13:204,600,735...204,694,836 		JBrowse link
G S Bace2 beta-secretase 2 enables IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chrNW_004936500:2,362,994...2,449,783
Ensembl chrNW_004936500:2,368,334...2,449,789 		JBrowse link
G D BACE2 beta-secretase 2 enables IEA UniProt
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr31:35,714,003...35,760,686
Ensembl chr31:35,713,149...35,760,681 		JBrowse link
G B BACE2 beta-secretase 2 enables IEA Ensembl
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 NCBI chr21:27,500,453...27,612,795
Ensembl chr21:40,831,203...40,938,280 		JBrowse link
G C Bace2 beta-secretase 2 enables ISO (PMID:10591213) UniProt PMID:10591213 NCBI chrNW_004955407:40,792,089...40,879,872
Ensembl chrNW_004955407:40,792,887...40,874,760 		JBrowse link
G R Bace2 beta-secretase 2 enables ISS
ISO		 GO_REF:0000024
(PMID:10591213)		 UniProt
RGD		 PMID:10591213 GO_REF:0000024 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G M Bace2 beta-site APP-cleaving enzyme 2 enables ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:97,157,928...97,244,136
Ensembl chr16:97,157,942...97,244,136 		JBrowse link
G H BACE2 beta-secretase 2 enables IEA
IDA		 (PMID:10591213) UniProt
InterPro		 PMID:10591213 GO_REF:0000002 GO_REF:0000043 NCBI chr21:41,168,160...41,282,530
Ensembl chr21:41,167,801...41,282,530 		JBrowse link
G G CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 7:130,589,592...130,610,845
Ensembl chr 7:130,591,166...130,610,899 		JBrowse link
G P CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G S Casp3 caspase 3 enables ISO (PMID:15231831), (PMID:23727203) MGI PMID:15231831 PMID:23727203 NCBI chrNW_004936554:4,571,072...4,593,765 JBrowse link
G D CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr16:45,920,074...45,940,507
Ensembl chr16:45,920,071...45,940,505 		JBrowse link
G B CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:176,793,190...176,815,023
Ensembl chr 4:189,018,422...189,040,185 		JBrowse link
G C Casp3 caspase 3 enables ISO (PMID:15231831), (PMID:23727203) MGI PMID:15231831 PMID:23727203 NCBI chrNW_004955403:24,315,712...24,326,271 JBrowse link
G R Casp3 caspase 3 enables ISO (PMID:15231831), (PMID:23727203) RGD PMID:15231831 PMID:23727203 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G M Casp3 caspase 3 enables IDA (PMID:15231831), (PMID:23727203) MGI PMID:15231831 PMID:23727203 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G H CASP3 caspase 3 enables IEA Ensembl GO_REF:0000107 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G N Casp7 caspase 7 enables ISO (MGI:7327228|PMID:35705808), (PMID:15231831) MGI PMID:15231831 PMID:35705808 MGI:7327228 NCBI chrNW_004624737:32,853,354...32,888,881
Ensembl chrNW_004624737:32,852,835...32,887,069 		JBrowse link
G G CASP7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:106,558,291...106,607,662
Ensembl chr 9:106,559,445...106,607,663 		JBrowse link
G P CASP7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr14:124,017,776...124,050,369
Ensembl chr14:124,019,164...124,050,365 		JBrowse link
G S Casp7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chrNW_004936486:4,082,664...4,114,942
Ensembl chrNW_004936486:4,088,372...4,114,955 		JBrowse link
G D CASP7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr28:24,599,866...24,630,018
Ensembl chr28:24,599,493...24,628,668 		JBrowse link
G B CASP7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr10:110,273,318...110,324,800
Ensembl chr10:113,707,780...113,758,626 		JBrowse link
G C Casp7 caspase 7 enables ISO (MGI:7327228|PMID:35705808), (PMID:15231831) MGI PMID:15231831 PMID:35705808 MGI:7327228 NCBI chrNW_004955431:18,685,408...18,723,221
Ensembl chrNW_004955431:18,686,190...18,723,524 		JBrowse link
G R Casp7 caspase 7 enables ISO (MGI:7327228|PMID:35705808), (PMID:15231831) RGD PMID:15231831 PMID:35705808 MGI:7327228 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G M Casp7 caspase 7 enables IDA (MGI:7327228|PMID:35705808), (PMID:15231831) MGI PMID:15231831 PMID:35705808 MGI:7327228 NCBI chr19:56,382,640...56,430,780
Ensembl chr19:56,385,561...56,430,776 		JBrowse link
G H CASP7 caspase 7 enables IEA Ensembl GO_REF:0000107 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907 		JBrowse link
G M Cntnap5a contactin associated protein-like 5A enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 1:115,612,467...116,515,053
Ensembl chr 1:115,612,486...116,515,053 		JBrowse link
G N Ctsd cathepsin D enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624767:14,661,058...14,671,116
Ensembl chrNW_004624767:14,660,936...14,671,671 		JBrowse link
G G CTSD cathepsin D enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:1,570,163...1,581,857
Ensembl chr 1:1,570,069...1,581,833 		JBrowse link
G P CTSD cathepsin D enables IEA
IBA		 InterPro
GO_Central
TreeGrafter
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:1,188,548...1,197,642
Ensembl chr 2:1,188,549...1,197,643 		JBrowse link
G S Ctsd cathepsin D enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936816:680,798...690,959
Ensembl chrNW_004936816:680,798...691,039 		JBrowse link
G D CTSD cathepsin D enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr18:46,010,440...46,019,457
Ensembl chr18:46,010,440...46,019,457 		JBrowse link
G B CTSD cathepsin D enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chr11:1,789,326...1,800,524 JBrowse link
G C Ctsd cathepsin D enables ISO (PMID:19293336) MGI PMID:19293336 NCBI chrNW_004955422:13,576,315...13,584,267
Ensembl chrNW_004955422:13,576,202...13,584,298 		JBrowse link
G R Ctsd cathepsin D enables IEA
ISO
IBA		 GO_REF:0000043
(PMID:19293336)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:19293336 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488 		JBrowse link
G M Ctsd cathepsin D enables IDA
IBA		 (PMID:19293336) MGI
GO_Central		 PMID:19293336 GO_REF:0000033 NCBI chr 7:141,929,647...141,941,564
Ensembl chr 7:141,929,648...141,941,775 		JBrowse link
G H CTSD cathepsin D enables IEA
IBA
TAS		 (PMID:3927292) UniProt
TreeGrafter
GO_Central
Ensembl
InterPro
PINC		 PMID:3927292 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573 		JBrowse link
G N Ctse cathepsin E enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624807:5,291,993...5,306,507
Ensembl chrNW_004624807:5,291,736...5,305,104 		JBrowse link
G G CTSE cathepsin E enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chr25:23,318,421...23,333,885
Ensembl chr25:23,319,248...23,332,980 		JBrowse link
G S Ctse cathepsin E enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936557:6,485,783...6,498,805
Ensembl chrNW_004936557:6,485,755...6,498,833 		JBrowse link
G D CTSE cathepsin E enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr38:2,368,711...2,380,554
Ensembl chr38:2,369,265...2,380,459 		JBrowse link
G B CTSE cathepsin E enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:181,617,421...181,632,260
Ensembl chr 1:185,900,746...185,915,519 		JBrowse link
G C Ctse cathepsin E enables ISO (PMID:7789521)
(MGI:87708|PMID:9180269)
PMID:8157122		 UniProt PMID:7789521 PMID:8157122 PMID:9180269 MGI:87708 RGD:8554034 NCBI chrNW_004955406:41,641,412...41,653,261
Ensembl chrNW_004955406:41,641,311...41,653,296 		JBrowse link
G R Ctse cathepsin E enables ISO
IBA
IDA		 (PMID:7789521)
GO_REF:0000033
(MGI:87708|PMID:9180269)
PMID:8157122		 RGD
GO_Central		 PMID:7789521 PMID:9180269 PMID:8157122 GO_REF:0000033 MGI:87708, RGD:8554034 NCBI chr13:43,091,954...43,114,509
Ensembl chr13:43,092,128...43,114,502 		JBrowse link
G M Ctse cathepsin E enables IDA
IBA
ISO		 (MGI:87708|PMID:9180269) UniProt
GO_Central
MGI		 PMID:9180269 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 MGI:4417868 MGI:4834177 MGI:87708 NCBI chr 1:131,566,052...131,603,245
Ensembl chr 1:131,566,044...131,603,243 		JBrowse link
G H CTSE cathepsin E enables IEA
IBA
IDA		 (PMID:7789521) Ensembl
TreeGrafter
GO_Central
InterPro
UniProt		 PMID:7789521 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:206,009,264...206,023,895
Ensembl chr 1:206,008,535...206,023,909 		JBrowse link
G P CYM chymosin enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 4:109,663,691...109,674,438 JBrowse link
G D CYM chymosin enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:41,517,094...41,528,216 JBrowse link
G R Cym chymosin enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:194,828,739...194,839,096
Ensembl chr 2:194,828,739...194,839,096 		JBrowse link
G M Cym chymosin enables IBA GO_Central GO_REF:0000033 NCBI chr 3:107,118,611...107,129,048
Ensembl chr 3:107,118,609...107,129,048 		JBrowse link
G N Ddi1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624918:1,177,679...1,179,208
Ensembl chrNW_004624918:1,177,614...1,179,393 		JBrowse link
G G DDI1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chr 1:95,423,135...95,425,366
Ensembl chr 1:95,423,431...95,424,621 		JBrowse link
G P DDI1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chr 9:34,503,087...34,505,026
Ensembl chr 9:34,503,716...34,504,921 		JBrowse link
G S Ddi1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936551:4,086,113...4,088,860
Ensembl chrNW_004936551:4,086,744...4,088,006 		JBrowse link
G D DDI1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chr 5:27,976,439...27,977,959
Ensembl chr 5:27,965,768...27,977,749 		JBrowse link
G B DDI1 DNA damage inducible 1 homolog 1 enables IEA InterPro GO_REF:0000002 NCBI chr11:98,981,511...98,983,500
Ensembl chr11:102,466,220...102,467,398 		JBrowse link
G R Ddi1 DNA-damage inducible 1 homolog 1 enables IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 8:3,596,658...3,598,505
Ensembl chr 8:3,595,149...3,598,533 		JBrowse link
G M Ddi1 DNA-damage inducible 1 enables IEA UniProt GO_REF:0000002 GO_REF:0000043 MGI:1354194 MGI:2152098 NCBI chr 9:6,265,028...6,266,547
Ensembl chr 9:6,262,733...6,269,846 		JBrowse link
G H DDI1 DNA damage inducible 1 homolog 1 enables IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000043 NCBI chr11:104,036,640...104,039,196
Ensembl chr11:104,036,640...104,039,196 		JBrowse link
G G DDI2 DNA damage inducible 1 homolog 2 enables ISO (PMID:27528193) UniProt PMID:27528193 NCBI chr20:116,640,166...116,680,403 JBrowse link
G D DDI2 DNA damage inducible 1 homolog 2 enables IEA InterPro GO_REF:0000002 NCBI chr 2:81,915,613...81,957,803 JBrowse link
G B DDI2 DNA damage inducible 1 homolog 2 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:14,757,327...14,810,959
Ensembl chr 1:15,749,497...15,790,263
Ensembl chr 1:15,749,497...15,790,263 		JBrowse link
G C Ddi2 DNA damage inducible 1 homolog 2 enables ISO (PMID:27528193) UniProt PMID:27528193 NCBI chrNW_004955527:2,498,211...2,534,768 JBrowse link
G R Ddi2 DNA damage inducible 1 homolog 2 enables ISO (PMID:27528193) RGD PMID:27528193 NCBI chr 5:153,989,591...154,035,342
Ensembl chr 5:153,995,589...154,035,283 		JBrowse link
G M Ddi2 DNA-damage inducible protein 2 enables ISS
ISO		 (MGI:6316441|PMID:27528193) UniProt
MGI		 PMID:27528193 GO_REF:0000119 MGI:4834177 MGI:6316441 NCBI chr 4:141,410,874...141,450,730
Ensembl chr 4:141,404,860...141,450,730 		JBrowse link
G H DDI2 DNA damage inducible 1 homolog 2 enables IEA
IDA		 (PMID:27528193) InterPro
UniProt		 PMID:27528193 GO_REF:0000002 GO_REF:0000043 NCBI chr 1:15,617,458...15,669,044
Ensembl chr 1:15,617,458...15,669,044 		JBrowse link
G R ENSRNOG00000067229 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 4:83,921,470...83,930,590 JBrowse link
G R ENSRNOG00000069797 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 4:11,438,116...11,449,855 JBrowse link
G R ENSRNOG00000071214 enables IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 4:70,862,239...70,962,565 JBrowse link
G H ERVK-6 endogenous retrovirus group K member 6, envelope enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043
G H ERVK-7 endogenous retrovirus group K member 7 enables IEA InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043
G B IFITM10 interferon induced transmembrane protein 10 enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr11:1,771,296...1,787,042 JBrowse link
G P LOC100522849 pregnancy-associated glycoprotein 2-like enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr 2:10,340,130...10,349,422 JBrowse link
G P LOC100523770 pregnancy-associated glycoprotein 2 enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,492,911...10,501,605 JBrowse link
G P LOC100523945 pregnancy-associated glycoprotein 2 enables IEA
IBA		 InterPro
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr 2:10,514,058...10,522,916 JBrowse link
G P LOC100524130 pregnancy-associated glycoprotein 2-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,537,302...10,547,265 JBrowse link
G P LOC100524300 pregnancy-associated glycoprotein 2-like enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,593,201...10,600,796 JBrowse link
G P LOC100524479 pregnancy-associated glycoprotein 2-like enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,574,818...10,582,603 JBrowse link
G P LOC100524786 pregnancy-associated glycoprotein-like enables IEA
IBA		 UniProt
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr 2:10,555,849...10,565,569 JBrowse link
G P LOC100737419 pregnancy-associated glycoprotein 2 enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,452,824...10,461,624 JBrowse link
G B LOC100971639 chymosin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:113,129,777...113,140,312 JBrowse link
G B LOC100989682 napsin-A-like enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr19:47,297,079...47,308,089 JBrowse link
G N LOC101704457 protein DDI1 homolog 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624764:1,880,654...1,931,669
Ensembl chrNW_004624764:1,885,163...1,924,258 		JBrowse link
G N LOC101707063 prolactin-inducible protein homolog enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624800:11,615,840...11,624,376 JBrowse link
G N LOC101714689 prolactin-inducible protein homolog enables IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624800:11,684,447...11,689,996 JBrowse link
G S LOC101971368 chymosin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936704:1,899,397...1,911,600 JBrowse link
G S LOC101972531 gastricsin enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,094,214...18,100,756 JBrowse link
G S LOC101972822 gastricsin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,181,008...18,187,477 JBrowse link
G S LOC101975705 pepsin F-like enables IEA Ensembl
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936581:1,796,801...1,805,492 JBrowse link
G S LOC101977339 gastricsin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,061,529...18,068,576 JBrowse link
G S LOC101977883 gastricsin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,117,571...18,123,873 JBrowse link
G S LOC101978161 gastricsin-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,141,608...18,148,233 JBrowse link
G P LOC102160003 uncharacterized LOC102160003 enables IEA InterPro GO_REF:0000002 NCBI chr17:3,796,414...3,800,145 JBrowse link
G G LOC103234519 pepsin A-2/A-3 enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:12,623,118...12,653,235 JBrowse link
G G LOC103234533 pepsin A enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:12,594,139...12,618,571 JBrowse link
G G LOC103235075 napsin-A-like enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:43,396,016...43,405,326 JBrowse link
G G LOC103235077 napsin-A enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:43,416,721...43,428,423
Ensembl chr 6:43,416,338...43,428,297 		JBrowse link
G P LOC106510029 uncharacterized LOC106510029 enables IEA InterPro GO_REF:0000002 NCBI chr  Y:20,197,112...20,202,540 JBrowse link
G P LOC110259249 pregnancy-associated glycoprotein 2-like enables IEA
IBA		 InterPro
GO_Central
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,280,973...10,290,060 JBrowse link
G P LOC110259250 pregnancy-associated glycoprotein 2-like enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,430,342...10,438,418 JBrowse link
G D LOC119872231 pepsin B-like enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118
G D LOC119874625 prolactin-inducible protein homolog enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118
G D LOC119878979 pepsin B-like enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118
G H LOC124906959 pepsin A-4-like enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118
G H LOC128966586 pepsin A-4-like enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118
G D LOC483802 pepsin F-like enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr18:55,154,472...55,184,172
Ensembl chr18:55,110,175...55,163,084 		JBrowse link
G N Napsa napsin A aspartic peptidase enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624832:4,150,415...4,158,399
Ensembl chrNW_004624832:4,150,298...4,162,432 		JBrowse link
G P NAPSA napsin A aspartic peptidase enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:55,221,203...55,230,609
Ensembl chr 6:55,221,205...55,230,449 		JBrowse link
G S Napsa napsin A aspartic peptidase enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936889:204,337...216,795
Ensembl chrNW_004936889:204,384...208,110 		JBrowse link
G D NAPSA napsin A aspartic peptidase enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr 1:106,351,842...106,361,592
Ensembl chr 1:106,318,488...106,374,987 		JBrowse link
G B NAPSA napsin A aspartic peptidase enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chr19:47,321,581...47,333,307
Ensembl chr19:56,225,421...56,232,822 		JBrowse link
G R Napsa napsin A aspartic peptidase enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094 		JBrowse link
G M Napsa napsin A aspartic peptidase enables IBA GO_Central GO_REF:0000033 NCBI chr 7:44,221,869...44,236,270
Ensembl chr 7:44,221,804...44,236,286 		JBrowse link
G H NAPSA napsin A aspartic peptidase enables NAS
IBA
IEA		 (PMID:9877162) UniProt
GO_Central
InterPro		 PMID:9877162 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr19:50,358,477...50,365,639
Ensembl chr19:50,358,472...50,365,830 		JBrowse link
G G NRIP2 nuclear receptor interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr11:2,892,520...2,902,377
Ensembl chr11:2,893,730...2,901,495 		JBrowse link
G S Nrip2 nuclear receptor interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936606:3,159,049...3,167,629
Ensembl chrNW_004936606:3,158,910...3,167,578 		JBrowse link
G D NRIP2 nuclear receptor interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr27:41,925,083...41,933,475
Ensembl chr27:41,925,730...41,931,669 		JBrowse link
G B NRIP2 nuclear receptor interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr12:2,945,844...2,956,155
Ensembl chr12:2,879,690...2,887,722 		JBrowse link
G R Nrip2 nuclear receptor interacting protein 2 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:161,673,964...161,684,055
Ensembl chr 4:161,639,356...161,684,070 		JBrowse link
G M Nrip2 nuclear receptor interacting protein 2 enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 6:128,374,780...128,386,747
Ensembl chr 6:128,376,259...128,393,390 		JBrowse link
G H NRIP2 nuclear receptor interacting protein 2 enables IEA InterPro GO_REF:0000002 NCBI chr12:2,825,348...2,835,035
Ensembl chr12:2,825,348...2,835,544 		JBrowse link
G N Nrip3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624766:1,112,365...1,134,442
Ensembl chrNW_004624766:1,112,369...1,134,446 		JBrowse link
G G NRIP3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chr 1:55,796,371...55,825,723
Ensembl chr 1:55,808,011...55,828,537 		JBrowse link
G S Nrip3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936528:9,074,348...9,094,906
Ensembl chrNW_004936528:9,074,294...9,094,906 		JBrowse link
G D NRIP3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chr21:32,331,161...32,354,264
Ensembl chr21:32,334,015...32,354,208 		JBrowse link
G B NRIP3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chr11:9,110,113...9,131,087
Ensembl chr11:8,850,948...8,871,413 		JBrowse link
G R Nrip3 nuclear receptor interacting protein 3 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 1:163,789,738...163,815,036
Ensembl chr 1:163,789,738...163,815,600 		JBrowse link
G M Nrip3 nuclear receptor interacting protein 3 enables IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 7:109,357,263...109,380,752
Ensembl chr 7:109,357,262...109,381,232 		JBrowse link
G H NRIP3 nuclear receptor interacting protein 3 enables IEA InterPro GO_REF:0000002 NCBI chr11:8,980,576...9,004,505
Ensembl chr11:8,965,682...9,005,288 		JBrowse link
G P PAG6 pregnancy-associated glycoprotein 6 enables IEA
IBA		 InterPro
GO_Central
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,311,350...10,386,887
Ensembl chr 2:10,379,084...10,386,868 		JBrowse link
G P PCLO piccolo presynaptic cytomatrix protein enables IEA InterPro GO_REF:0000002 NCBI chr 9:97,114,503...97,513,081
Ensembl chr 9:97,114,511...97,513,072 		JBrowse link
G D PGA pepsinogen 5, group I (pepsinogen A) enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr18:55,131,441...55,140,119
Ensembl chr18:55,110,175...55,163,084 		JBrowse link
G H PGA3 pepsinogen A3 enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr11:61,203,515...61,213,098
Ensembl chr11:61,203,307...61,213,098 		JBrowse link
G H PGA4 pepsinogen A4 enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr11:61,222,347...61,231,694
Ensembl chr11:61,222,347...61,231,694 		JBrowse link
G P PGA5 pepsinogen 5, group I (pepsinogen A) enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,244,300...10,252,644
Ensembl chr 2:10,244,187...10,252,680 		JBrowse link
G R Pga5 pepsinogen A5 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:207,317,021...207,327,156
Ensembl chr 1:207,317,021...207,327,156 		JBrowse link
G M Pga5 pepsinogen 5, group I enables IDA
IBA		 (PMID:11566730) MGI
GO_Central		 PMID:11566730 GO_REF:0000033 NCBI chr19:10,646,321...10,655,435
Ensembl chr19:10,646,320...10,655,435 		JBrowse link
G H PGA5 pepsinogen A5 enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr11:61,241,175...61,251,444
Ensembl chr11:61,241,175...61,251,444 		JBrowse link
G P PGB pepsinogen B enables IEA
IBA		 InterPro
GO_Central
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 4:108,951,665...108,962,111
Ensembl chr 4:108,951,665...108,962,111 		JBrowse link
G D PGB1 pepsinogen B1 enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 6:40,708,460...40,718,462
Ensembl chr 6:40,646,351...40,718,462 		JBrowse link
G N Pgc progastricsin enables IEA Ensembl
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624754:17,311,743...17,319,675
Ensembl chrNW_004624754:17,311,644...17,319,764 		JBrowse link
G G PGC progastricsin enables IEA Ensembl
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr17:30,414,769...30,424,708
Ensembl chr17:30,415,124...30,424,766 		JBrowse link
G P PGC progastricsin enables IEA
IBA		 UniProt
GO_Central
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:36,922,269...36,951,380
Ensembl chr 7:36,922,271...36,951,349 		JBrowse link
G S Pgc progastricsin enables IEA UniProt
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004936476:18,039,709...18,046,510 JBrowse link
G D PGC progastricsin enables ISO (PMID:12759353) UniProt PMID:12759353 NCBI chr12:10,425,137...10,435,129 JBrowse link
G B PGC progastricsin enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:41,321,932...41,330,494
Ensembl chr 6:42,627,222...42,637,514 		JBrowse link
G C Pgc progastricsin enables ISO (PMID:12759353) UniProt PMID:12759353 NCBI chrNW_004955437:8,142,523...8,153,044
Ensembl chrNW_004955437:8,142,661...8,151,339 		JBrowse link
G R Pgc progastricsin enables ISO
IBA		 (PMID:12759353)
GO_REF:0000033		 RGD
GO_Central		 PMID:12759353 GO_REF:0000033 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682 		JBrowse link
G M Pgc progastricsin (pepsinogen C) enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr17:48,037,767...48,045,403
Ensembl chr17:48,037,767...48,045,407 		JBrowse link
G H PGC progastricsin enables IMP
IBA
IEA
TAS		 (PMID:12759353)
(PMID:3335549)		 UniProt
GO_Central
InterPro
PINC		 PMID:3335549 PMID:12759353 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 NCBI chr 6:41,736,711...41,747,397
Ensembl chr 6:41,736,711...41,754,109 		JBrowse link
G G PIP prolactin induced protein enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr21:112,015,420...112,024,133
Ensembl chr21:112,016,135...112,024,030 		JBrowse link
G P PIP prolactin induced protein enables IEA TreeGrafter GO_REF:0000118 NCBI chr18:7,110,528...7,117,274 JBrowse link
G S Pip prolactin induced protein enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936527:540,051...544,586
Ensembl chrNW_004936527:540,008...544,586 		JBrowse link
G D PIP prolactin induced protein enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:6,491,424...6,498,175
Ensembl chr16:6,491,424...6,498,133 		JBrowse link
G B PIP prolactin induced protein enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:135,127,479...135,135,117 JBrowse link
G R Pip prolactin induced protein enables ISO
IBA
IEA		 (PMID:10713110)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:10713110 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921 		JBrowse link
G M Pip prolactin induced protein enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 6:41,824,483...41,828,999
Ensembl chr 6:41,824,469...41,828,999 		JBrowse link
G H PIP prolactin induced protein enables IMP
IBA		 (PMID:10713110) UniProt
GO_Central		 PMID:10713110 GO_REF:0000033 NCBI chr 7:143,132,077...143,139,739
Ensembl chr 7:143,132,077...143,139,739 		JBrowse link
G P PPAG3 pregnancy-associated glycoprotein 3 enables IEA
IBA		 InterPro
TreeGrafter
GO_Central
UniProt		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000043 GO_REF:0000118 NCBI chr 2:10,474,866...10,482,943
Ensembl chr 2:10,474,866...10,482,984 		JBrowse link
G N Prr14l proline rich 14 like enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624747:8,093,170...8,160,108
Ensembl chrNW_004624747:8,089,865...8,160,141 		JBrowse link
G N Psen1 presenilin 1 enables IEA UniProt GO_REF:0000104 NCBI chrNW_004624734:28,200,358...28,272,684
Ensembl chrNW_004624734:28,200,140...28,272,743 		JBrowse link
G G PSEN1 presenilin 1 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr24:50,394,310...50,476,521
Ensembl chr24:50,405,590...50,472,132 		JBrowse link
G P PSEN1 presenilin 1 enables IEA UniProt
Ensembl		 GO_REF:0000104 GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G S Psen1 presenilin 1 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chrNW_004936488:2,464,623...2,528,807
Ensembl chrNW_004936488:2,464,527...2,530,065 		JBrowse link
G D PSEN1 presenilin 1 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G B PSEN1 presenilin 1 enables IEA Ensembl
UniProt		 GO_REF:0000104 GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G C Psen1 presenilin 1 enables ISO (PMID:12684521) MGI PMID:12684521 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737 		JBrowse link
G R Psen1 presenilin 1 enables ISO MGI:1930934 (PMID:12684521) RGD PMID:12684521 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G M Psen1 presenilin 1 enables IMP (PMID:12684521) MGI PMID:12684521 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G H PSEN1 presenilin 1 enables IEA
NAS		 (PMID:24217950) Ensembl
ARUK-UCL
UniProt		 PMID:24217950 GO_REF:0000104 GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G N Psen2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chrNW_004624771:17,183,538...17,205,460
Ensembl chrNW_004624771:17,183,447...17,224,188 		JBrowse link
G G PSEN2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chr25:2,862,354...2,888,735
Ensembl chr25:2,862,251...2,877,386 		JBrowse link
G P PSEN2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G S Psen2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chrNW_004936526:3,584,194...3,611,719
Ensembl chrNW_004936526:3,584,188...3,614,074 		JBrowse link
G D PSEN2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G B PSEN2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G H PSEN2 presenilin 2 enables IEA UniProt GO_REF:0000104 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G N Ren renin enables IEA InterPro
TreeGrafter
UniProt		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000118 NCBI chrNW_004624807:6,817,472...6,827,374
Ensembl chrNW_004624807:6,817,195...6,827,462 		JBrowse link
G G REN renin enables IEA Ensembl
TreeGrafter
InterPro
UniProt		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr25:25,159,816...25,193,620
Ensembl chr25:25,183,037...25,193,420 		JBrowse link
G P REN renin enables IEA
IBA		 Ensembl
TreeGrafter
GO_Central
UniProt
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:64,809,143...64,822,605
Ensembl chr 9:64,809,146...64,822,658 		JBrowse link
G S Ren renin enables IEA UniProt
TreeGrafter
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936567:598,044...607,628
Ensembl chrNW_004936567:598,048...607,497 		JBrowse link
G D REN renin enables IEA
IBA		 UniProt
TreeGrafter
GO_Central
Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr38:744,540...766,998
Ensembl chr38:744,614...755,012 		JBrowse link
G B REN renin enables IEA UniProt
TreeGrafter
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000003 GO_REF:0000043 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:179,757,653...179,769,530
Ensembl chr 1:184,046,117...184,057,393 		JBrowse link
G C Ren renin enables ISO (PMID:12045255), (PMID:4289389), (PMID:4322712), (PMID:4330891), (PMID:4360430)
(PMID:12045255), (PMID:20927107)		 Reactome
UniProt		 PMID:4289389 PMID:4322712 PMID:4330891 PMID:4360430 PMID:12045255 More... NCBI chrNW_004955406:40,016,624...40,026,286
Ensembl chrNW_004955406:40,016,630...40,026,286 		JBrowse link
G R Ren renin enables IEA
IBA
ISO		 GO_REF:0000043
GO_REF:0000033
(PMID:20927107), (PMID:4289389), (PMID:4322712), (PMID:4330891), (PMID:4360430)
(PMID:12045255)		 UniProt
GO_Central
RGD		 PMID:4289389 PMID:4322712 PMID:4330891 PMID:4360430 PMID:12045255 More... GO_REF:0000033 GO_REF:0000043 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489 		JBrowse link
G H REN renin enables IEA
IBA
IDA
EXP		 (PMID:12045255), (PMID:20927107)
(PMID:12045255), (PMID:4289389), (PMID:4322712), (PMID:4330891), (PMID:4360430)		 UniProt
GO_Central
InterPro
Reactome		 PMID:4289389 PMID:4322712 PMID:4330891 PMID:4360430 PMID:12045255 More... GO_REF:0000002 GO_REF:0000003 GO_REF:0000033 GO_REF:0000043 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G M Ren1 renin 1 structural enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 1:133,278,412...133,288,058
Ensembl chr 1:133,278,248...133,288,063 		JBrowse link
G M Ren2 renin 2 tandem duplication of Ren1 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177
G G RSC1A1 regulator of solute carriers 1 enables IEA InterPro GO_REF:0000002 Ensembl chr20:116,635,130...116,680,403 JBrowse link
G P RSC1A1 regulator of solute carriers 1 enables IEA InterPro GO_REF:0000002 NCBI chr 1:268,428,423...268,429,766
NCBI chr 6:74,846,976...74,865,376
Ensembl chr 6:74,809,350...74,855,423 		JBrowse link
G S Rsc1a1 regulator of solute carriers 1 enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936474:3,284,512...3,312,366
Ensembl chrNW_004936474:3,307,377...3,312,066
Ensembl chrNW_004936474:3,307,377...3,312,066 		JBrowse link
G R RT1-CE15 RT1 class I, locus CE15 enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563
Ensembl chr20:3,264,172...3,279,563 		JBrowse link
G N Sppl2c signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chrNW_004624849:2,469,076...2,471,365
Ensembl chrNW_004624849:2,468,699...2,471,428 		JBrowse link
G G SPPL2C signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chr16:60,059,144...60,062,178 JBrowse link
G P SPPL2C signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chr12:17,238,339...17,245,060
Ensembl chr12:17,240,736...17,242,823 		JBrowse link
G S Sppl2c signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chrNW_004936541:2,340,302...2,342,380
Ensembl chrNW_004936541:2,340,302...2,343,247 		JBrowse link
G D SPPL2C signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chr 9:9,703,119...9,705,300
Ensembl chr 9:9,703,230...9,705,212 		JBrowse link
G B SPPL2C signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chr17:11,323,494...11,325,924
Ensembl chr17:11,637,880...11,639,934 		JBrowse link
G C Sppl2c signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chrNW_004955478:10,368,379...10,370,624
Ensembl chrNW_004955478:10,365,857...10,370,548 		JBrowse link
G R Sppl2c signal peptide peptidase like 2C enables ISO (PMID:30733280) RGD PMID:30733280 NCBI chr10:89,095,279...89,097,487
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G M Sppl2c signal peptide peptidase 2C enables IDA (PMID:30733280) UniProt PMID:30733280 NCBI chr11:104,077,153...104,081,992
Ensembl chr11:104,077,153...104,081,989 		JBrowse link
G H SPPL2C signal peptide peptidase like 2C enables ISO (PMID:30733280) UniProt PMID:30733280 NCBI chr17:45,844,881...45,847,067
Ensembl chr17:45,844,881...45,847,067 		JBrowse link
G M Sva seminal vesicle antigen enables IBA GO_Central GO_REF:0000033 NCBI chr 6:42,015,328...42,019,785
Ensembl chr 6:42,015,328...42,019,785 		JBrowse link
G R Sval1 seminal vesicle antigen-like 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:70,845,228...70,856,192
Ensembl chr 4:70,845,228...70,856,192 		JBrowse link
G M Sval1 seminal vesicle antigen-like 1 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:41,928,562...41,933,032
Ensembl chr 6:41,928,564...41,933,032 		JBrowse link
G R Sval2 seminal vesicle antigen-like 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:70,809,366...70,813,330
Ensembl chr 4:70,809,366...70,813,340 		JBrowse link
G M Sval2 seminal vesicle antigen-like 2 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:41,837,241...41,841,347
Ensembl chr 6:41,829,923...41,841,347 		JBrowse link
G M Sval3 seminal vesicle antigen-like 3 enables IBA GO_Central GO_REF:0000033 NCBI chr 6:41,945,074...41,950,024
Ensembl chr 6:41,945,074...41,950,024 		JBrowse link
G P TMEM9B TMEM9 domain family member B enables IEA InterPro GO_REF:0000002 NCBI chr 9:462,623...510,263
Ensembl chr 9:462,643...484,344
Ensembl chr 9:462,643...484,344 		JBrowse link
G P TMEM9B TMEM9 domain family member B enables IEA InterPro GO_REF:0000002 NCBI chr 9:518,449...519,710
Ensembl chr 9:462,643...521,013 		JBrowse link
aspartic endopeptidase activity, intramembrane cleaving term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G M H13 histocompatibility 13 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:152,511,292...152,550,590
Ensembl chr 2:152,511,381...152,550,590 		JBrowse link
G N Hm13 histocompatibility minor 13 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624741:924,040...977,646
Ensembl chrNW_004624741:921,023...977,703 		JBrowse link
G G HM13 histocompatibility minor 13 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 2:35,925,316...35,975,209
Ensembl chr 2:35,925,290...35,977,982 		JBrowse link
G P HM13 histocompatibility minor 13 enables IEA
IBA		 Ensembl
GO_Central
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr17:35,248,575...35,288,431
Ensembl chr17:35,248,570...35,288,539 		JBrowse link
G S Hm13 histocompatibility minor 13 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936485:18,539,873...18,583,605
Ensembl chrNW_004936485:18,539,826...18,583,813 		JBrowse link
G D HM13 histocompatibility minor 13 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr24:21,026,851...21,067,773
Ensembl chr24:21,026,366...21,071,165 		JBrowse link
G B HM13 histocompatibility minor 13 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:27,803,597...27,859,384
Ensembl chr20:28,441,285...28,501,001 		JBrowse link
G C Hm13 histocompatibility minor 13 enables ISO (PMID:25239945)
(PMID:16873890)		 UniProt PMID:16873890 PMID:25239945 NCBI chrNW_004955422:29,365,722...29,408,788
Ensembl chrNW_004955422:29,362,724...29,408,840 		JBrowse link
G R Hm13 histocompatibility minor 13 enables ISO
IBA		 (PMID:16873890), (PMID:25239945)
GO_REF:0000033		 RGD
GO_Central		 PMID:16873890 PMID:25239945 GO_REF:0000033 NCBI chr 3:141,145,792...141,183,557
Ensembl chr 3:141,145,782...141,184,703 		JBrowse link
G H HM13 histocompatibility minor 13 enables TAS
IEA
IBA
IMP
IDA		 (PMID:16873890)
(PMID:25239945)		 Reactome
TreeGrafter
GO_Central
InterPro
UniProt		 PMID:16873890 PMID:25239945 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 Reactome:R-HSA-9708457 NCBI chr20:31,514,442...31,569,543
Ensembl chr20:31,514,428...31,577,923 		JBrowse link
G R Mcts2 MCTS family member 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,163,330...141,164,108 JBrowse link
G N Ncstn nicastrin contributes_to ISO (PMID:16371134) MGI PMID:16371134 NCBI chrNW_004624794:908,227...923,474
Ensembl chrNW_004624794:905,857...924,003 		JBrowse link
G G NCSTN nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chr20:3,590,044...3,606,205
Ensembl chr20:3,590,725...3,606,066 		JBrowse link
G P NCSTN nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chr 4:90,121,209...90,142,934
Ensembl chr 4:90,119,002...90,142,890 		JBrowse link
G S Ncstn nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chrNW_004936740:285,789...301,918
Ensembl chrNW_004936740:285,657...302,111 		JBrowse link
G D NCSTN nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chr38:21,878,071...21,891,362
Ensembl chr38:21,685,868...21,892,097 		JBrowse link
G B NCSTN nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chr 1:135,697,592...135,713,293
Ensembl chr 1:139,618,229...139,633,911 		JBrowse link
G C Ncstn nicastrin contributes_to ISO (PMID:16371134) MGI PMID:16371134 NCBI chrNW_004955468:12,111,078...12,126,404
Ensembl chrNW_004955468:12,111,078...12,127,033 		JBrowse link
G R Ncstn nicastrin contributes_to ISO MGI:1202717|MGI:3522097 (PMID:16371134) RGD PMID:16371134 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G M Ncstn nicastrin contributes_to IGI (PMID:16371134) MGI PMID:16371134 NCBI chr 1:171,893,580...171,910,356
Ensembl chr 1:171,893,580...171,910,362 		JBrowse link
G H NCSTN nicastrin enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI		 PMID:16371134 GO_REF:0000107 NCBI chr 1:160,343,383...160,358,949
Ensembl chr 1:160,343,294...160,358,952 		JBrowse link
G N Psen1 presenilin 1 enables
contributes_to		 IEA
ISO		 (PMID:16371134) InterPro
MGI		 PMID:16371134 GO_REF:0000002 NCBI chrNW_004624734:28,200,358...28,272,684
Ensembl chrNW_004624734:28,200,140...28,272,743 		JBrowse link
G G PSEN1 presenilin 1 enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI
InterPro		 PMID:16371134 GO_REF:0000002 GO_REF:0000107 NCBI chr24:50,394,310...50,476,521
Ensembl chr24:50,405,590...50,472,132 		JBrowse link
G P PSEN1 presenilin 1 enables
contributes_to		 IEA
ISO
IBA		 (PMID:16371134) Ensembl
MGI
GO_Central
InterPro		 PMID:16371134 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr 7:96,478,179...96,567,884
Ensembl chr 7:96,478,190...96,569,130 		JBrowse link
G S Psen1 presenilin 1 enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI
InterPro		 PMID:16371134 GO_REF:0000002 GO_REF:0000107 NCBI chrNW_004936488:2,464,623...2,528,807
Ensembl chrNW_004936488:2,464,527...2,530,065 		JBrowse link
G D PSEN1 presenilin 1 enables
contributes_to		 IEA
ISO
IBA
ISS		 (PMID:16371134) Ensembl
MGI
GO_Central
InterPro
UniProt		 PMID:16371134 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:46,495,551...46,569,532
Ensembl chr 8:46,495,624...46,569,532 		JBrowse link
G B PSEN1 presenilin 1 enables
contributes_to		 IEA
ISO		 (PMID:16371134) Ensembl
MGI
InterPro		 PMID:16371134 GO_REF:0000002 GO_REF:0000107 NCBI chr14:53,718,299...53,802,684
Ensembl chr14:72,579,024...72,663,876 		JBrowse link
G C Psen1 presenilin 1 enables
contributes_to		 ISO (PMID:26280335)
(PMID:16371134)
(PMID:21206757)
(PMID:17428795)		 UniProt
MGI		 PMID:16371134 PMID:17428795 PMID:21206757 PMID:26280335 NCBI chrNW_004955523:2,128,529...2,210,737
Ensembl chrNW_004955523:2,128,529...2,210,737 		JBrowse link
G R Psen1 presenilin 1 enables
contributes_to		 ISS
ISO
IBA		 GO_REF:0000024
MGI:109284 (PMID:21206757)
MGI:1891700|MGI:3522097 (PMID:16371134)
GO_REF:0000033
(PMID:17428795), (PMID:26280335)		 UniProt
RGD
GO_Central		 PMID:16371134 PMID:17428795 PMID:21206757 PMID:26280335 GO_REF:0000024 GO_REF:0000033 NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G M Psen1 presenilin 1 enables
contributes_to		 ISO
IGI
IMP
IBA		 (PMID:21206757)
(PMID:16371134)		 MGI
GO_Central		 PMID:16371134 PMID:21206757 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr12:83,734,926...83,781,869
Ensembl chr12:83,734,926...83,781,973 		JBrowse link
G H PSEN1 presenilin 1 enables
contributes_to		 IMP
ISO
IBA
IEA
IDA		 (PMID:17428795)
(PMID:16371134)
(PMID:26280335)		 UniProt
MGI
GO_Central
InterPro
Ensembl		 PMID:16371134 PMID:17428795 PMID:26280335 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr14:73,136,417...73,223,691
Ensembl chr14:73,136,418...73,223,691 		JBrowse link
G N Psen2 presenilin 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004624771:17,183,538...17,205,460
Ensembl chrNW_004624771:17,183,447...17,224,188 		JBrowse link
G G PSEN2 presenilin 2 enables IEA InterPro GO_REF:0000002 NCBI chr25:2,862,354...2,888,735
Ensembl chr25:2,862,251...2,877,386 		JBrowse link
G P PSEN2 presenilin 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr10:14,532,556...14,561,862
Ensembl chr10:14,532,767...14,577,251 		JBrowse link
G S Psen2 presenilin 2 enables IEA InterPro GO_REF:0000002 NCBI chrNW_004936526:3,584,194...3,611,719
Ensembl chrNW_004936526:3,584,188...3,614,074 		JBrowse link
G D PSEN2 presenilin 2 enables IEA InterPro GO_REF:0000002 NCBI chr 7:38,147,157...38,163,023
Ensembl chr 7:38,147,173...38,166,722 		JBrowse link
G B PSEN2 presenilin 2 enables IEA InterPro GO_REF:0000002 NCBI chr 1:202,328,987...202,354,440
Ensembl chr 1:207,320,937...207,346,295 		JBrowse link
G C Psen2 presenilin 2 enables ISO (PMID:21206757)
(PMID:12684521)		 MGI PMID:12684521 PMID:21206757 NCBI chrNW_004955406:5,727,367...5,748,798
Ensembl chrNW_004955406:5,727,367...5,752,234 		JBrowse link
G R Psen2 presenilin 2 enables IBA
ISO		 GO_REF:0000033
MGI:1202717|MGI:1930939 (PMID:12684521), (PMID:21206757)		 GO_Central
RGD		 PMID:12684521 PMID:21206757 GO_REF:0000033 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174 		JBrowse link
G M Psen2 presenilin 2 enables IGI
IMP
IBA		 (PMID:21206757)
(PMID:12684521)		 MGI
GO_Central		 PMID:12684521 PMID:21206757 GO_REF:0000033 NCBI chr 1:180,054,569...180,091,030
Ensembl chr 1:180,054,569...180,091,003 		JBrowse link
G H PSEN2 presenilin 2 enables IEA
IBA		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726 		JBrowse link
G N Sppl2a signal peptide peptidase like 2A enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624731:9,430,702...9,469,961
Ensembl chrNW_004624731:9,430,790...9,473,839 		JBrowse link
G G SPPL2A signal peptide peptidase like 2A enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr26:32,574,585...32,633,473
Ensembl chr26:32,574,612...32,634,034 		JBrowse link
G P SPPL2A signal peptide peptidase like 2A enables IEA
IBA		 Ensembl
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:121,067,638...121,134,896
Ensembl chr 1:121,067,454...121,134,888 		JBrowse link
G S Sppl2a signal peptide peptidase like 2A enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936471:12,700,777...12,730,509
Ensembl chrNW_004936471:12,701,014...12,729,995 		JBrowse link
G D SPPL2A signal peptide peptidase like 2A enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr30:16,593,834...16,638,435
Ensembl chr30:16,596,967...16,745,608 		JBrowse link
G B SPPL2A signal peptide peptidase like 2A enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr15:29,660,190...29,718,477
Ensembl chr15:47,997,304...48,055,239 		JBrowse link
G C Sppl2a signal peptide peptidase like 2A enables ISO (PMID:2313285) UniProt PMID:2313285 NCBI chrNW_004955409:3,642,113...3,670,779
Ensembl chrNW_004955409:3,645,555...3,670,551 		JBrowse link
G R Sppl2a signal peptide peptidase-like 2A enables ISO
IBA		 (PMID:2313285)
GO_REF:0000033		 RGD
GO_Central		 PMID:2313285 GO_REF:0000033 NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264 		JBrowse link
G M Sppl2a signal peptide peptidase like 2A enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 2:126,732,311...126,775,706
Ensembl chr 2:126,732,311...126,775,155 		JBrowse link
G H SPPL2A signal peptide peptidase like 2A enables TAS
IBA
IEA
IDA		 (PMID:2313285) Reactome
GO_Central
InterPro
UniProt		 PMID:2313285 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-8863101 NCBI chr15:50,702,266...50,765,706
Ensembl chr15:50,702,266...50,765,948 		JBrowse link
G N Sppl2b signal peptide peptidase like 2B NOT|enables ISO
IEA		 (PMID:16873890) UniProt
TreeGrafter
InterPro		 PMID:16873890 GO_REF:0000002 GO_REF:0000118 NCBI chrNW_004624828:6,564,127...6,576,663
Ensembl chrNW_004624828:6,562,426...6,576,609 		JBrowse link
G G SPPL2B signal peptide peptidase like 2B NOT|enables ISO
IEA		 (PMID:16873890) UniProt
TreeGrafter
InterPro
Ensembl		 PMID:16873890 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:2,121,568...2,142,746
Ensembl chr 6:2,121,634...2,144,682 		JBrowse link
G P SPPL2B signal peptide peptidase like 2B NOT|enables ISO
IBA
IEA		 (PMID:16873890) UniProt
GO_Central
TreeGrafter
InterPro
Ensembl		 PMID:16873890 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:76,230,060...76,247,067
Ensembl chr 2:76,230,061...76,247,051 		JBrowse link
G S Sppl2b signal peptide peptidase like 2B NOT|enables ISO
IEA		 (PMID:16873890) UniProt
TreeGrafter
InterPro
Ensembl		 PMID:16873890 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936588:1,399,125...1,408,676
Ensembl chrNW_004936588:1,399,085...1,408,783 		JBrowse link
G D SPPL2B signal peptide peptidase like 2B NOT|enables ISO
IEA		 (PMID:16873890) UniProt
TreeGrafter
InterPro
Ensembl		 PMID:16873890 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr20:56,714,306...56,730,388
Ensembl chr20:56,712,390...56,757,938 		JBrowse link
G B SPPL2B signal peptide peptidase like 2B NOT|enables ISO
IEA		 (PMID:16873890) UniProt
TreeGrafter
InterPro
Ensembl		 PMID:16873890 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr19:1,337,570...1,355,755
Ensembl chr19:2,309,360...2,331,951 		JBrowse link
G C Sppl2b signal peptide peptidase like 2B enables
NOT|enables		 ISO (PMID:19114711), (PMID:22194595)
(PMID:16873890)
(PMID:2313285)		 UniProt PMID:2313285 PMID:16873890 PMID:19114711 PMID:22194595 NCBI chrNW_004955495:5,816,979...5,829,938
Ensembl chrNW_004955495:5,818,337...5,829,889 		JBrowse link
G R Sppl2b signal peptide peptidase-like 2B NOT|enables ISS
IEA
IBA
ISO		 GO_REF:0000024
GO_REF:0000118
GO_REF:0000033
GO_REF:0000002
GO_REF:0000107
(PMID:19114711), (PMID:22194595), (PMID:2313285)
(PMID:16873890)		 UniProt
TreeGrafter
GO_Central
InterPro
Ensembl
RGD		 PMID:2313285 PMID:16873890 PMID:19114711 PMID:22194595 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:8,843,918...8,856,642
Ensembl chr 7:8,843,918...8,856,608 		JBrowse link
G M Sppl2b signal peptide peptidase like 2B NOT|enables ISO
IBA		 (PMID:16873890) UniProt
GO_Central		 PMID:16873890 GO_REF:0000033 NCBI chr10:80,691,067...80,704,542
Ensembl chr10:80,691,109...80,704,542 		JBrowse link
G H SPPL2B signal peptide peptidase like 2B enables
NOT|enables		 TAS
IBA
IEA
IDA
IMP		 (PMID:2313285)
(PMID:19114711), (PMID:22194595)
(PMID:16873890)		 Reactome
GO_Central
InterPro
UniProt		 PMID:2313285 PMID:16873890 PMID:19114711 PMID:22194595 GO_REF:0000002 GO_REF:0000033 Reactome:R-HSA-8863101 NCBI chr19:2,328,684...2,355,095
Ensembl chr19:2,328,615...2,355,095 		JBrowse link
G N Sppl2c signal peptide peptidase like 2C enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624849:2,469,076...2,471,365
Ensembl chrNW_004624849:2,468,699...2,471,428 		JBrowse link
G G SPPL2C signal peptide peptidase like 2C enables ISO (MGI:6281843|PMID:30733280), (MGI:7332329|PMID:35960805), (MGI:7387163|PMID:30733281) UniProt PMID:30733280 PMID:30733281 PMID:35960805 MGI:6281843 MGI:7332329 MGI:7387163 NCBI chr16:60,059,144...60,062,178 JBrowse link
G P SPPL2C signal peptide peptidase like 2C enables IEA
IBA		 Ensembl
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 NCBI chr12:17,238,339...17,245,060
Ensembl chr12:17,240,736...17,242,823 		JBrowse link
G S Sppl2c signal peptide peptidase like 2C enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936541:2,340,302...2,342,380
Ensembl chrNW_004936541:2,340,302...2,343,247 		JBrowse link
G D SPPL2C signal peptide peptidase like 2C enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:9,703,119...9,705,300
Ensembl chr 9:9,703,230...9,705,212 		JBrowse link
G B SPPL2C signal peptide peptidase like 2C enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr17:11,323,494...11,325,924
Ensembl chr17:11,637,880...11,639,934 		JBrowse link
G C Sppl2c signal peptide peptidase like 2C enables ISO (MGI:6281843|PMID:30733280), (MGI:7332329|PMID:35960805), (MGI:7387163|PMID:30733281) UniProt PMID:30733280 PMID:30733281 PMID:35960805 MGI:6281843 MGI:7332329 MGI:7387163 NCBI chrNW_004955478:10,368,379...10,370,624
Ensembl chrNW_004955478:10,365,857...10,370,548 		JBrowse link
G R Sppl2c signal peptide peptidase like 2C enables ISO
IBA		 (MGI:6281843|PMID:30733280), (MGI:7332329|PMID:35960805), (MGI:7387163|PMID:30733281)
GO_REF:0000033		 RGD
GO_Central		 PMID:30733280 PMID:30733281 PMID:35960805 GO_REF:0000033 MGI:6281843 MGI:7332329 MGI:7387163 NCBI chr10:89,095,279...89,097,487
Ensembl chr10:89,095,261...89,098,580 		JBrowse link
G M Sppl2c signal peptide peptidase 2C enables IDA
IBA		 (MGI:6281843|PMID:30733280), (MGI:7332329|PMID:35960805), (MGI:7387163|PMID:30733281) UniProt
GO_Central		 PMID:30733280 PMID:30733281 PMID:35960805 GO_REF:0000033 MGI:6281843 MGI:7332329 MGI:7387163 NCBI chr11:104,077,153...104,081,992
Ensembl chr11:104,077,153...104,081,989 		JBrowse link
G H SPPL2C signal peptide peptidase like 2C enables ISS
IBA
IEA		 UniProt
GO_Central
InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr17:45,844,881...45,847,067
Ensembl chr17:45,844,881...45,847,067 		JBrowse link
G N Sppl3 signal peptide peptidase like 3 enables ISO (PMID:2313285)
(PMID:16873890)		 UniProt PMID:2313285 PMID:16873890 NCBI chrNW_004624747:12,795,803...12,925,319
Ensembl chrNW_004624747:12,795,563...12,928,649 		JBrowse link
G G SPPL3 signal peptide peptidase like 3 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr11:116,125,042...116,267,226
Ensembl chr11:116,124,221...116,267,108 		JBrowse link
G P SPPL3 signal peptide peptidase like 3 enables IEA
IBA		 Ensembl
TreeGrafter
GO_Central
InterPro		 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr14:40,699,931...40,870,288
Ensembl chr14:40,699,937...40,822,761 		JBrowse link
G S Sppl3 signal peptide peptidase like 3 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936668:193,753...229,859
Ensembl chrNW_004936668:193,723...231,088 		JBrowse link
G D SPPL3 signal peptide peptidase like 3 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr26:16,620,236...16,760,616
Ensembl chr26:16,621,455...16,760,623 		JBrowse link
G B SPPL3 signal peptide peptidase like 3 enables IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr12:118,351,199...118,489,579
Ensembl chr12:121,723,881...121,773,429 		JBrowse link
G C Sppl3 signal peptide peptidase like 3 enables ISO (PMID:2313285)
(PMID:16873890)		 UniProt PMID:2313285 PMID:16873890 NCBI chrNW_004955455:10,849,627...10,905,515
Ensembl chrNW_004955455:10,760,804...10,907,024 		JBrowse link
G R Sppl3 signal peptide peptidase like 3 enables ISO
IBA		 (PMID:16873890), (PMID:2313285)
GO_REF:0000033		 RGD
GO_Central		 PMID:2313285 PMID:16873890 GO_REF:0000033 NCBI chr12:41,515,635...41,600,079
Ensembl chr12:41,515,640...41,600,126 		JBrowse link
G M Sppl3 signal peptide peptidase 3 enables ISO
IBA		 MGI
GO_Central		 GO_REF:0000033 GO_REF:0000119 MGI:4834177 NCBI chr 5:115,149,204...115,236,849
Ensembl chr 5:115,149,196...115,236,849 		JBrowse link
G H SPPL3 signal peptide peptidase like 3 enables IMP
IEA
IBA
IDA		 (PMID:16873890)
(PMID:2313285)		 UniProt
TreeGrafter
GO_Central
InterPro		 PMID:2313285 PMID:16873890 GO_REF:0000002 GO_REF:0000033 GO_REF:0000118 NCBI chr12:120,762,510...120,904,358
Ensembl chr12:120,762,510...120,904,358 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 190015
    catalytic activity 54309
      hydrolase activity 22904
        peptidase activity 5902
          endopeptidase activity 3834
            aspartic-type endopeptidase activity 288
              aspartic endopeptidase activity, intramembrane cleaving 81
              aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process 0
paths to the root