CASP3 (caspase 3) - Rat Genome Database

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Gene: CASP3 (caspase 3) Canis lupus familiaris
Analyze
Symbol: CASP3
Name: caspase 3
RGD ID: 12072547
Description: ENCODES a protein that exhibits cysteine-type endopeptidase activity involved in apoptotic process (ortholog); cysteine-type endopeptidase activity involved in apoptotic signaling pathway (ortholog); cysteine-type endopeptidase activity involved in execution phase of apoptosis (ortholog); INVOLVED IN intrinsic apoptotic signaling pathway in response to osmotic stress; positive regulation of apoptotic process; anterior neural tube closure (ortholog); PARTICIPATES IN apoptotic cell death pathway; extrinsic apoptotic pathway; FasL mediated signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Liver Failure (ortholog); Acute Lung Injury (ortholog); FOUND IN cytoplasm; death-inducing signaling complex (ortholog); neuronal cell body (ortholog); INTERACTS WITH all-trans-retinoic acid; calcium oxalate; carvedilol
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CASP-3; caspase-3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,920,074 - 45,940,507 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,920,071 - 45,940,505 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1646,413,238 - 46,434,538 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01648,136,012 - 48,157,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1648,135,662 - 48,157,268 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11646,101,180 - 46,122,422 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,715,535 - 46,736,806 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,848,704 - 46,870,015 (+)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
acute myocardial infarction  (ISO)
acute necrotizing pancreatitis  (ISO)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
atherosclerosis  (ISO)
bacterial infectious disease  (ISO)
Brain Contusion  (ISO)
brain glioma  (ISO)
Brain Hypoxia-Ischemia  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
bronchopulmonary dysplasia  (ISO)
Burns  (ISO)
calcinosis  (ISO)
cataract  (ISO)
Cerebral Hemorrhage  (ISO)
cervical cancer  (ISO)
chemical colitis  (ISO)
Chronic Hepatitis  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon cancer  (ISO)
Colonic Neoplasms  (ISO)
congestive heart failure  (ISO)
Contrast-Induced Nephropathy  (ISO)
Copper-Overload Cirrhosis  (ISO)
cryptorchidism  (ISO)
diabetes mellitus  (ISO)
diabetic angiopathy  (ISO)
Diabetic Cardiomyopathies  (ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
dilated cardiomyopathy  (ISO)
Edema  (ISO)
endometritis  (ISO)
Endotoxemia  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Mammary Neoplasms  (ISO)
Experimental Radiation Injuries  (ISO)
Fetal Growth Retardation  (ISO)
gastric ulcer  (ISO)
genetic disease  (ISO)
heart disease  (ISO)
heart valve disease  (ISO)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (ISO)
Huntington's disease  (ISO)
Hypercholesterolemia  (ISO)
hypertension  (ISO)
hypertrophic cardiomyopathy  (ISO)
Hypoxia  (ISO)
impotence  (ISO)
Insulin Resistance  (ISO)
intermittent claudication  (ISO)
intestinal disease  (ISO)
Intestinal Reperfusion Injury  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (ISO)
liver cirrhosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung non-small cell carcinoma  (ISO)
Lung Reperfusion Injury  (ISO)
middle cerebral artery infarction  (ISO)
Mycoplasma Infections  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
Neoplasm Metastasis  (ISO)
Nerve Degeneration  (ISO)
nervous system disease  (ISO)
osteoarthritis  (ISO)
Osteoarthritis, Experimental  (ISO)
Oxygen-Induced Retinopathy  (ISO)
pancreatitis  (ISO)
Parkinson's disease  (ISO)
Parkinsonism  (ISO)
pre-malignant neoplasm  (ISO)
prostate cancer  (ISO)
Prostatic Neoplasms  (ISO)
renal cell carcinoma  (ISO)
Reperfusion Injury  (ISO)
retinal detachment  (ISO)
retinal disease  (ISO)
salivary gland disease  (ISO)
sciatic neuropathy  (ISO)
scrapie  (ISO)
Sepsis  (ISO)
severe acute respiratory syndrome  (ISO)
spermatic cord torsion  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
stomach cancer  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
Testis Reperfusion Injury  (ISO)
toxic encephalopathy  (ISO)
transient cerebral ischemia  (ISO)
transitional cell carcinoma  (ISO)
traumatic brain injury  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
Ventricular Remodeling  (ISO)
Viral Myocarditis  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anterior neural tube closure  (IEA,ISO)
apoptotic process  (IEA,ISO)
axonal fasciculation  (ISO)
B cell homeostasis  (IEA,ISO)
cell fate commitment  (IEA,ISO)
cellular response to organic cyclic compound  (ISO)
cellular response to organic substance  (IEA,ISO)
cellular response to staurosporine  (IEA)
DNA damage response  (IEA,ISO)
epithelial cell apoptotic process  (IEA,ISO)
erythrocyte differentiation  (IBA,IEA)
execution phase of apoptosis  (IBA,IEA,ISO)
fibroblast apoptotic process  (IEA,ISO)
glial cell apoptotic process  (IEA,ISO)
heart development  (IEA,ISO)
hippocampus development  (ISO)
intracellular signal transduction  (ISO)
intrinsic apoptotic signaling pathway  (IEA)
intrinsic apoptotic signaling pathway in response to osmotic stress  (IDA,IEA)
keratinocyte differentiation  (IBA,IEA,ISO)
learning or memory  (ISO)
leukocyte apoptotic process  (ISO)
luteolysis  (ISO)
negative regulation of activated T cell proliferation  (IEA,ISO)
negative regulation of B cell proliferation  (IEA,ISO)
negative regulation of cell cycle  (IEA,ISO)
negative regulation of cytokine production  (IEA)
neuron apoptotic process  (IEA,ISO)
neuron differentiation  (IBA,IEA,ISO)
neurotrophin TRK receptor signaling pathway  (IEA,ISO)
positive regulation of amyloid-beta formation  (IEA,ISS)
positive regulation of apoptotic process  (IDA,IEA,ISO)
positive regulation of neuron apoptotic process  (IBA,IEA,ISO)
positive regulation of pyroptosis  (IEA)
protein catabolic process  (IEA,ISO)
protein maturation  (IEA)
protein processing  (IEA,ISO)
proteolysis  (IBA,IEA,ISS)
pyroptosis  (IEA)
regulation of protein stability  (IEA,ISS)
response to amino acid  (ISO)
response to auditory stimulus  (ISO)
response to cobalt ion  (ISO)
response to estradiol  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to lipopolysaccharide  (ISO)
response to metal ion  (ISO)
response to nicotine  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (IEA,ISO)
response to UV  (IEA,ISO)
response to wounding  (IEA,ISO)
response to X-ray  (ISO)
response to xenobiotic stimulus  (ISO)
sensory perception of sound  (IEA,ISO)
striated muscle cell differentiation  (ISO)
T cell homeostasis  (IEA,ISO)

Cellular Component
cytoplasm  (IBA,IDA,IEA)
cytosol  (IEA)
death-inducing signaling complex  (IBA,ISO)
neuronal cell body  (ISO)
nucleus  (IEA,ISO)

References
Additional References at PubMed
PMID:15187371   PMID:20198571   PMID:21716255   PMID:22037840   PMID:22301074   PMID:24495616   PMID:25966088   PMID:30032202  


Genomics

Comparative Map Data
CASP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11645,920,074 - 45,940,507 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1645,920,071 - 45,940,505 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1646,413,238 - 46,434,538 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01648,136,012 - 48,157,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1648,135,662 - 48,157,268 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11646,101,180 - 46,122,422 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01646,715,535 - 46,736,806 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01646,848,704 - 46,870,015 (+)NCBIUU_Cfam_GSD_1.0
CASP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh384184,627,696 - 184,649,447 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl4184,627,696 - 184,650,062 (-)EnsemblGRCh38hg38GRCh38
GRCh374185,548,850 - 185,570,601 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364185,785,844 - 185,807,623 (-)NCBINCBI36Build 36hg18NCBI36
Build 344185,923,999 - 185,945,750NCBI
Celera4182,877,510 - 182,899,293 (-)NCBICelera
Cytogenetic Map4q35.1NCBI
HuRef4181,303,305 - 181,324,956 (-)NCBIHuRef
CHM1_14185,525,377 - 185,547,156 (-)NCBICHM1_1
T2T-CHM13v2.04187,971,378 - 187,993,131 (-)NCBIT2T-CHM13v2.0
Casp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39847,070,326 - 47,092,733 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl847,070,326 - 47,092,724 (+)EnsemblGRCm39 Ensembl
GRCm38846,617,291 - 46,639,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl846,617,291 - 46,639,689 (+)EnsemblGRCm38mm10GRCm38
MGSCv37847,702,803 - 47,724,071 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36848,116,266 - 48,137,534 (+)NCBIMGSCv36mm8
Celera849,300,031 - 49,321,270 (+)NCBICelera
Cytogenetic Map8B1.1NCBI
cM Map826.39NCBI
Casp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81652,395,539 - 52,413,794 (-)NCBIGRCr8
mRatBN7.21645,662,910 - 45,681,171 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1645,662,910 - 45,684,648 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1651,061,544 - 51,079,742 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01654,429,112 - 54,447,305 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01649,700,916 - 49,719,114 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01648,845,011 - 48,863,249 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1648,845,012 - 48,863,204 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01648,560,090 - 48,578,325 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41648,944,226 - 48,962,420 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11648,944,301 - 48,962,495 (-)NCBI
Celera1643,665,975 - 43,684,168 (-)NCBICelera
Cytogenetic Map16q11NCBI
Casp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540324,315,712 - 24,326,271 (+)NCBIChiLan1.0ChiLan1.0
CASP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v23182,351,669 - 182,373,528 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan14182,713,461 - 182,735,319 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v04176,793,190 - 176,815,023 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14189,018,422 - 189,040,217 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4189,018,422 - 189,040,185 (-)Ensemblpanpan1.1panPan2
Casp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494333,516,817 - 33,538,924 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365544,571,072 - 4,593,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CASP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1545,742,751 - 45,764,213 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11545,744,320 - 45,753,252 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21552,291,074 - 52,299,625 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CASP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.17130,589,592 - 130,610,845 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl7130,591,166 - 130,610,899 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037110,841,187 - 110,862,527 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in CASP3
204 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 2 14 3 6 3 6 12 10 5
Low 3 8 3 3 6 8 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001003042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001419300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038452308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038497950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038560423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038624472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038624473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038624474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038690239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB085580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSCAFT00000012385   ⟹   ENSCAFP00000011475
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1645,920,071 - 45,940,505 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000085761   ⟹   ENSCAFP00000053993
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1645,920,071 - 45,940,004 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845027267   ⟹   ENSCAFP00845021455
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1648,135,662 - 48,155,520 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845027303   ⟹   ENSCAFP00845021487
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1648,135,971 - 48,157,268 (+)Ensembl
RefSeq Acc Id: XM_038452305   ⟹   XP_038308233
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1646,413,256 - 46,434,538 (+)NCBI
RefSeq Acc Id: XM_038452306   ⟹   XP_038308234
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1646,413,289 - 46,434,538 (+)NCBI
RefSeq Acc Id: XM_038452307   ⟹   XP_038308235
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1646,413,238 - 46,434,538 (+)NCBI
RefSeq Acc Id: XM_038452308   ⟹   XP_038308236
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1646,413,288 - 46,434,538 (+)NCBI
RefSeq Acc Id: XM_038497947   ⟹   XP_038353875
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11646,101,186 - 46,122,422 (+)NCBI
RefSeq Acc Id: XM_038497948   ⟹   XP_038353876
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11646,101,180 - 46,122,422 (+)NCBI
RefSeq Acc Id: XM_038497949   ⟹   XP_038353877
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11646,101,216 - 46,122,422 (+)NCBI
RefSeq Acc Id: XM_038497950   ⟹   XP_038353878
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11646,101,186 - 46,120,248 (+)NCBI
RefSeq Acc Id: XM_038560420   ⟹   XP_038416348
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01646,848,725 - 46,870,015 (+)NCBI
RefSeq Acc Id: XM_038560421   ⟹   XP_038416349
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01646,848,758 - 46,870,015 (+)NCBI
RefSeq Acc Id: XM_038560422   ⟹   XP_038416350
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01646,848,704 - 46,870,015 (+)NCBI
RefSeq Acc Id: XM_038560423   ⟹   XP_038416351
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01646,848,757 - 46,870,015 (+)NCBI
RefSeq Acc Id: XM_038624472   ⟹   XP_038480400
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01646,715,553 - 46,736,806 (+)NCBI
RefSeq Acc Id: XM_038624473   ⟹   XP_038480401
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01646,715,535 - 46,736,806 (+)NCBI
RefSeq Acc Id: XM_038624474   ⟹   XP_038480402
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01646,715,584 - 46,736,806 (+)NCBI
RefSeq Acc Id: XM_038690234   ⟹   XP_038546162
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01648,136,030 - 48,157,278 (+)NCBI
RefSeq Acc Id: XM_038690235   ⟹   XP_038546163
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01648,136,063 - 48,157,278 (+)NCBI
RefSeq Acc Id: XM_038690236   ⟹   XP_038546164
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01648,136,012 - 48,157,278 (+)NCBI
RefSeq Acc Id: XM_038690237   ⟹   XP_038546165
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01648,136,062 - 48,157,278 (+)NCBI
RefSeq Acc Id: XM_038690239   ⟹   XP_038546167
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01648,136,030 - 48,155,100 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001406228 (Get FASTA)   NCBI Sequence Viewer  
  NP_001406229 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308233 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308234 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308235 (Get FASTA)   NCBI Sequence Viewer  
  XP_038308236 (Get FASTA)   NCBI Sequence Viewer  
  XP_038353875 (Get FASTA)   NCBI Sequence Viewer  
  XP_038353876 (Get FASTA)   NCBI Sequence Viewer  
  XP_038353877 (Get FASTA)   NCBI Sequence Viewer  
  XP_038353878 (Get FASTA)   NCBI Sequence Viewer  
  XP_038416348 (Get FASTA)   NCBI Sequence Viewer  
  XP_038416349 (Get FASTA)   NCBI Sequence Viewer  
  XP_038416350 (Get FASTA)   NCBI Sequence Viewer  
  XP_038416351 (Get FASTA)   NCBI Sequence Viewer  
  XP_038480400 (Get FASTA)   NCBI Sequence Viewer  
  XP_038480401 (Get FASTA)   NCBI Sequence Viewer  
  XP_038480402 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546162 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546163 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546164 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546165 (Get FASTA)   NCBI Sequence Viewer  
  XP_038546167 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB92962 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCAFP00000011475.4
  ENSCAFP00000053993.1
  ENSCAFP00030022727.1
  ENSCAFP00030022824.1
  ENSCAFP00040021743.1
  ENSCAFP00040021839.1
  ENSCAFP00845021455.1
  ENSCAFP00845021487
  ENSCAFP00845021487.1
GenBank Protein Q8MKI5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: ENSCAFP00000011475   ⟸   ENSCAFT00000012385
RefSeq Acc Id: ENSCAFP00000053993   ⟸   ENSCAFT00000085761
RefSeq Acc Id: XP_038353876   ⟸   XM_038497948
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038353875   ⟸   XM_038497947
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038353878   ⟸   XM_038497950
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038353877   ⟸   XM_038497949
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038480401   ⟸   XM_038624473
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038480400   ⟸   XM_038624472
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038480402   ⟸   XM_038624474
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038546164   ⟸   XM_038690236
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038546162   ⟸   XM_038690234
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038546167   ⟸   XM_038690239
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038546165   ⟸   XM_038690237
- Peptide Label: isoform X3
- UniProtKB: Q8MKI5 (UniProtKB/Swiss-Prot),   A0A8C0JL25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038546163   ⟸   XM_038690235
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RJX4 (UniProtKB/TrEMBL),   A0A8I3NRN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308235   ⟸   XM_038452307
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038308233   ⟸   XM_038452305
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038308236   ⟸   XM_038452308
- Peptide Label: isoform X3
- UniProtKB: Q8MKI5 (UniProtKB/Swiss-Prot),   A0A8C0JL25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038308234   ⟸   XM_038452306
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RJX4 (UniProtKB/TrEMBL),   A0A8I3NRN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416350   ⟸   XM_038560422
- Peptide Label: isoform X3
- UniProtKB: Q8MKI5 (UniProtKB/Swiss-Prot),   A0A8C0JL25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416348   ⟸   XM_038560420
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RJX4 (UniProtKB/TrEMBL),   A0A8I3NRN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416351   ⟸   XM_038560423
- Peptide Label: isoform X3
- UniProtKB: Q8MKI5 (UniProtKB/Swiss-Prot),   A0A8C0JL25 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038416349   ⟸   XM_038560421
- Peptide Label: isoform X2
- UniProtKB: A0A8C0RJX4 (UniProtKB/TrEMBL),   A0A8I3NRN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845021455   ⟸   ENSCAFT00845027267
RefSeq Acc Id: ENSCAFP00845021487   ⟸   ENSCAFT00845027303
Promoters
RGD ID:13686136
Promoter ID:EPDNEW_C4204
Type:initiation region
Name:CASP3_1
Description:caspase 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11645,920,558 - 45,920,618EPDNEW

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007750 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030014028 UniProtKB/TrEMBL
  ENSCAFG00040013526 UniProtKB/TrEMBL
  ENSCAFG00845015288 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012385.6 UniProtKB/TrEMBL
  ENSCAFT00000085761.2 UniProtKB/TrEMBL
  ENSCAFT00030026021.1 UniProtKB/TrEMBL
  ENSCAFT00030026134.1 UniProtKB/TrEMBL
  ENSCAFT00040025009.1 UniProtKB/TrEMBL
  ENSCAFT00040025120.1 UniProtKB/TrEMBL
  ENSCAFT00845027267.1 UniProtKB/TrEMBL
  ENSCAFT00845027303 ENTREZGENE
  ENSCAFT00845027303.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1460 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Caspase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase_cys_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Caspase_his_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14_caspase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14_p10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14_p20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_C14A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene CASP3 ENTREZGENE
PANTHER CASPASE-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10454 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Peptidase_C14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS IL1BCENZYME UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CASPASE_CYS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_HIS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_P10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CASPASE_P20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CASc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8C0JL25 ENTREZGENE
  A0A8C0RJX4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0SK38_CANLF UniProtKB/TrEMBL
  A0A8I3NRN4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3P4S5_CANLF UniProtKB/TrEMBL
  CASP3_CANLF UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:38734 ENTREZGENE