ONTOLOGY REPORT - ANNOTATIONS |
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Term: | negative regulation of peptide secretion |
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Accession: | GO:0002792
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browse the term
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Definition: | Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. |
Synonyms: | exact_synonym: | down regulation of peptide secretion; downregulation of peptide secretion |
| narrow_synonym: | inhibition of peptide secretion |
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Cd74 |
CD74 molecule |
involved_in |
ISO IEA |
(PMID:19849849) GO_REF:0000107 |
RGD Ensembl |
PMID:19849849 |
GO_REF:0000107 |
NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
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Ptger4 |
prostaglandin E receptor 4 |
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IMP |
endothelin-1 |
RGD |
PMID:15560120 |
RGD:10043380 |
NCBI chr 2:54,330,563...54,347,451
Ensembl chr 2:54,335,424...54,346,670
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Crhbp |
corticotropin releasing hormone binding protein |
involved_in |
IEA IBA IDA ISO |
GO_REF:0000107 GO_REF:0000033 PMID:1846945 (PMID:1846945) |
Ensembl GO_Central RGD |
PMID:1846945 PMID:1846945 |
GO_REF:0000033 GO_REF:0000107, RGD:69816 |
NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710
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Cartpt |
CART prepropeptide |
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IDA |
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RGD |
PMID:16443761 |
RGD:2313632 |
NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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Crh |
corticotropin releasing hormone |
involved_in |
IDA IBA |
GO_REF:0000033 |
GO_Central RGD |
PMID:12606499 |
GO_REF:0000033, RGD:704397 |
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Lep |
leptin |
involved_in |
ISO |
(PMID:21234744) |
RGD |
PMID:21234744 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Nucb2 |
nucleobindin 2 |
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IDA |
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RGD |
PMID:21828181 |
RGD:9831189 |
NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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Kalrn |
kalirin, RhoGEF kinase |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 MGI:5551305 (PMID:23116210) |
Ensembl RGD |
PMID:23116210 |
GO_REF:0000107 |
NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
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Madd |
MAP-kinase activating death domain |
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IDA |
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RGD |
PMID:16473592 |
RGD:9588640 |
NCBI chr 3:77,114,330...77,157,865
Ensembl chr 3:77,114,314...77,157,701
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Ptpn11 |
protein tyrosine phosphatase, non-receptor type 11 |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 MGI:3522021 (PMID:15520383) |
Ensembl RGD |
PMID:15520383 |
GO_REF:0000107 |
NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
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Sirt1 |
sirtuin 1 |
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IMP |
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RGD |
PMID:23292070 |
RGD:9585999 |
NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Sstr1 |
somatostatin receptor 1 |
involved_in |
ISO |
(PMID:16543371) |
RGD |
PMID:16543371 |
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NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
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Sstr2 |
somatostatin receptor 2 |
involved_in |
ISO |
(PMID:16543371) |
RGD |
PMID:16543371 |
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NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
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Sstr3 |
somatostatin receptor 3 |
involved_in |
ISO |
(PMID:16543371) |
RGD |
PMID:16543371 |
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NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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Abcc8 |
ATP binding cassette subfamily C member 8 |
involved_in |
IDA ISO |
MGI:2388392 (PMID:16924481), (PMID:25771886) |
RGD |
PMID:16924481 PMID:25771886 PMID:15163199 |
RGD:1598646 |
NCBI chr 1:96,598,568...96,679,563
Ensembl chr 1:96,598,647...96,679,510
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Acvr1c |
activin A receptor type 1C |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 MGI:3512292 (PMID:18480258) |
Ensembl RGD |
PMID:18480258 |
GO_REF:0000107 |
NCBI chr 3:42,815,490...42,892,423
Ensembl chr 3:42,822,610...42,892,327
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Adra2a |
adrenoceptor alpha 2A |
involved_in |
ISO |
(PMID:10952463) (PMID:17992256), (PMID:1898674) |
RGD |
PMID:1898674 PMID:10952463 PMID:17992256 |
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NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Bmp8a |
bone morphogenetic protein 8a |
involved_in |
ISO |
(PMID:22579288) |
RGD |
PMID:22579288 |
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NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785
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Ccn3 |
cellular communication network factor 3 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:23705021) |
UniProt RGD |
PMID:23705021 |
GO_REF:0000024 |
NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
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Chga |
chromogranin A |
involved_in |
IBA |
GO_REF:0000033 |
GO_Central |
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GO_REF:0000033 |
NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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Drd2 |
dopamine receptor D2 |
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IMP |
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RGD |
PMID:18216393 |
RGD:2311570 |
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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F2rl1 |
F2R like trypsin receptor 1 |
involved_in |
ISO |
MGI:2179844 (PMID:17992256) |
RGD |
PMID:17992256 |
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NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
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Fam3d |
FAM3 metabolism regulating signaling molecule D |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:12160727) |
UniProt RGD |
PMID:12160727 |
GO_REF:0000024 |
NCBI chr15:16,538,881...16,574,468
Ensembl chr15:16,539,489...16,573,034
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Fbn1 |
fibrillin 1 |
involved_in |
ISO |
(PMID:30997682) |
RGD |
PMID:30997682 |
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NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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Ffar2 |
free fatty acid receptor 2 |
involved_in |
ISO |
MGI:2685324 (PMID:25581519), (PMID:26075576) |
RGD |
PMID:25581519 PMID:26075576 |
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NCBI chr 1:86,071,855...86,075,049
Ensembl chr 1:86,072,184...86,075,033
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Ffar3 |
free fatty acid receptor 3 |
involved_in |
ISO |
MGI:2441731|MGI:3829251 (PMID:25581519), (PMID:26091414), (PMID:32073900) |
RGD |
PMID:25581519 PMID:26091414 PMID:32073900 |
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NCBI chr 1:86,105,388...86,106,728
Ensembl chr 1:86,104,920...86,106,849
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Foxo1 |
forkhead box O1 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:12219087), (PMID:27457971) |
UniProt RGD |
PMID:12219087 PMID:27457971 |
GO_REF:0000024 |
NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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Ghrl |
ghrelin and obestatin prepropeptide |
acts_upstream_of_or_within |
IDA ISO |
PMID:17130496 MGI:3709886 (PMID:17130496) |
RGD |
PMID:17130496 PMID:17130496 |
RGD:8553721 |
NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
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Ghsr |
growth hormone secretagogue receptor |
acts_upstream_of_or_within |
IDA |
PMID:17130496 |
MGI |
PMID:17130496 |
RGD:8553721 |
NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865
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Gnao1 |
G protein subunit alpha o1 |
involved_in |
IEA ISO |
GO_REF:0000107 MGI:4941848 (PMID:20622165) |
Ensembl RGD |
PMID:20622165 |
GO_REF:0000107 |
NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493
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Gnaz |
G protein subunit alpha z |
involved_in |
ISO |
MGI:3575007 (PMID:18096703) |
RGD |
PMID:18096703 |
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NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907
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Hadh |
hydroxyacyl-CoA dehydrogenase |
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IMP |
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RGD |
PMID:17491019 |
RGD:2302227 |
NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
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Hdac1 |
histone deacetylase 1 |
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IMP |
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RGD |
PMID:22772764 |
RGD:9590127 |
NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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Inhbb |
inhibin subunit beta B |
involved_in acts_upstream_of_or_within |
IEA ISO ISS |
GO_REF:0000107 MGI:1857203 (PMID:18480258) GO_REF:0000024 |
Ensembl RGD UniProt |
PMID:18480258 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
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Irs1 |
insulin receptor substrate 1 |
involved_in |
IMP IEA ISO |
PMID:12435589 GO_REF:0000107 (PMID:15572028) |
Ensembl RGD |
PMID:15572028 PMID:12435589 |
GO_REF:0000107, RGD:729325 |
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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Kcnb1 |
potassium voltage-gated channel subfamily B member 1 |
involved_in |
IEA ISO ISS |
GO_REF:0000107 (PMID:17767909) GO_REF:0000024 |
Ensembl RGD UniProt |
PMID:17767909 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
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Kcnj11 |
potassium inwardly-rectifying channel, subfamily J, member 11 |
involved_in |
ISO |
(PMID:8923010) MGI:2178821 (PMID:16924481), (PMID:33196462) |
RGD |
PMID:8923010 PMID:16924481 PMID:33196462 |
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NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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Kcnq1 |
potassium voltage-gated channel subfamily Q member 1 |
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IDA |
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RGD |
PMID:16133261 |
RGD:1581603 |
NCBI chr 1:198,291,711...198,624,683
Ensembl chr 1:198,291,766...198,624,669
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Midn |
midnolin |
acts_upstream_of_or_within |
IDA |
PMID:24187134 |
MGI |
PMID:24187134 |
RGD:8655525 |
NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
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Mtnr1a |
melatonin receptor 1A |
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IMP |
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RGD |
PMID:22288848 |
RGD:9686057 |
NCBI chr16:47,144,461...47,163,919
Ensembl chr16:47,144,461...47,163,919
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Mtnr1b |
melatonin receptor 1B |
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IMP |
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RGD |
PMID:18363673 |
RGD:9588673 |
NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
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Nos1 |
nitric oxide synthase 1 |
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IMP |
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RGD |
PMID:17130471 |
RGD:1642149 |
NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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Npff |
neuropeptide FF-amide peptide precursor |
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IDA |
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RGD |
PMID:1704109 |
RGD:2316580 |
NCBI chr 7:133,654,530...133,655,319
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Pde8b |
phosphodiesterase 8B |
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IMP |
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RGD |
PMID:17991719 |
RGD:2312519 |
NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
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Pfkl |
phosphofructokinase, liver type |
acts_upstream_of_or_within |
ISO |
(PMID:9287040) |
RGD |
PMID:9287040 |
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NCBI chr20:10,664,285...10,686,324
Ensembl chr20:10,664,272...10,686,315
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Ppp3ca |
protein phosphatase 3 catalytic subunit alpha |
involved_in |
IMP |
PMID:19965390 |
BHF-UCL |
PMID:19965390 |
RGD:2316628 |
NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
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Prkn |
parkin RBR E3 ubiquitin protein ligase |
involved_in acts_upstream_of_or_within |
ISS IEA ISO |
GO_REF:0000024 GO_REF:0000107 (PMID:24187134) |
ParkinsonsUK-UCL Ensembl RGD |
PMID:24187134 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Psmd9 |
proteasome 26S subunit, non-ATPase 9 |
involved_in |
IMP |
PMID:16099819 |
BHF-UCL |
PMID:16099819 |
RGD:8554418 |
NCBI chr12:33,337,182...33,357,468
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Ptger3 |
prostaglandin E receptor 3 |
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IDA |
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RGD |
PMID:10531320 |
RGD:10043332 |
NCBI chr 2:246,606,131...246,750,970
Ensembl chr 2:246,606,183...246,684,434
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Ptpn11 |
protein tyrosine phosphatase, non-receptor type 11 |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 MGI:3522021 (PMID:15520383) |
Ensembl RGD |
PMID:15520383 |
GO_REF:0000107 |
NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
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Rest |
RE1-silencing transcription factor |
involved_in |
ISS IEA ISO |
GO_REF:0000024 GO_REF:0000107 (PMID:20942606) |
UniProt Ensembl RGD |
PMID:20942606 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
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Rptor |
regulatory associated protein of MTOR, complex 1 |
involved_in |
ISO |
(PMID:23092880) |
RGD |
PMID:23092880 |
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NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
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Sfrp1 |
secreted frizzled-related protein 1 |
involved_in |
IEA ISO |
GO_REF:0000107 (PMID:17994217) |
Ensembl RGD |
PMID:17994217 |
GO_REF:0000107 |
NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286
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Sirt4 |
sirtuin 4 |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:17715127) MGI:3769237|MGI:95753 (PMID:16959573) |
RGD |
PMID:16959573 PMID:17715127 |
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NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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Srebf1 |
sterol regulatory element binding transcription factor 1 |
acts_upstream_of_or_within |
ISO |
MGI:2177773 (PMID:16890542) |
RGD |
PMID:16890542 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Stxbp5l |
syntaxin binding protein 5L |
acts_upstream_of_or_within |
ISO |
(PMID:21998599) |
RGD |
PMID:21998599 |
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NCBI chr11:63,334,667...63,654,270
Ensembl chr11:63,334,667...63,657,014
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Sytl4 |
synaptotagmin-like 4 |
involved_in acts_upstream_of_or_within |
IEA ISO |
GO_REF:0000107 (PMID:16890542) |
Ensembl RGD |
PMID:16890542 |
GO_REF:0000107 |
NCBI chr X:97,135,496...97,185,867
Ensembl chr X:97,135,500...97,185,854
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Uts2 |
urotensin 2 |
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IMP |
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RGD |
PMID:17931748 |
RGD:2306798 |
NCBI chr 5:161,450,846...161,456,235
Ensembl chr 5:161,450,846...161,456,237
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Vsnl1 |
visinin-like 1 |
acts_upstream_of_or_within |
ISO |
(PMID:16731532) |
RGD |
PMID:16731532 |
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NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479
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Adra2a |
adrenoceptor alpha 2A |
involved_in |
ISO IMP |
(PMID:19965390) |
RGD |
PMID:19965390 PMID:19965390 |
RGD:2316628 |
NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365
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Crhr2 |
corticotropin releasing hormone receptor 2 |
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IMP |
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RGD |
PMID:17360501 |
RGD:2306172 |
NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
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Eny2 |
ENY2, transcription and export complex 2 subunit |
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IMP |
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RGD |
PMID:22649445 |
RGD:9590329 |
NCBI chr 7:75,581,215...75,605,903
Ensembl chr 7:75,581,240...75,605,897
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Fkbp1b |
FKBP prolyl isomerase 1B |
acts_upstream_of_or_within |
ISO |
MGI:2182644 (PMID:19805579) |
RGD |
PMID:19805579 |
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NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
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Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
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IMP |
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RGD |
PMID:20610886 |
RGD:5508687 |
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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Jagn1 |
jagunal homolog 1 |
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IMP |
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RGD |
PMID:26882284 |
RGD:11520872 |
NCBI chr 4:146,591,577...146,596,287
Ensembl chr 4:146,591,510...146,596,288
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Klf7 |
KLF transcription factor 7 |
involved_in |
ISO |
(PMID:16339272) |
RGD |
PMID:16339272 |
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NCBI chr 9:65,433,683...65,526,372
Ensembl chr 9:65,437,167...65,526,261
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Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
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IMP |
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RGD |
PMID:19690174 |
RGD:7495848 |
NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
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Mup4l1 |
major urinary protein 4 like 1 |
involved_in |
ISS |
GO_REF:0000024 |
UniProt |
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GO_REF:0000024 |
NCBI chr 5:75,221,340...75,224,797
Ensembl chr 5:75,142,157...75,564,845
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Ndufaf2 |
NADH:ubiquinone oxidoreductase complex assembly factor 2 |
acts_upstream_of_or_within |
ISO |
(PMID:22587331) |
RGD |
PMID:22587331 |
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NCBI chr 2:39,535,680...39,647,378
Ensembl chr 2:39,535,689...39,647,316
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Pde1c |
phosphodiesterase 1C |
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IMP |
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RGD |
PMID:18706893 |
RGD:2302857 |
NCBI chr 4:85,300,858...85,777,948
Ensembl chr 4:85,300,858...85,863,219
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Pde3b |
phosphodiesterase 3B |
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IMP |
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RGD |
PMID:18706893 |
RGD:2302857 |
NCBI chr 1:168,606,762...168,770,078
Ensembl chr 1:168,607,022...168,769,334
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Pde4c |
phosphodiesterase 4C |
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IMP |
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RGD |
PMID:18706893 |
RGD:2302857 |
NCBI chr16:18,690,727...18,711,555
Ensembl chr16:18,691,700...18,710,640
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G |
Pde8b |
phosphodiesterase 8B |
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IMP |
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RGD |
PMID:18706893 |
RGD:2302857 |
NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209
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G |
Pim3 |
Pim-3 proto-oncogene, serine/threonine kinase |
involved_in |
ISS ISO IEA |
GO_REF:0000024 (PMID:21099329) GO_REF:0000107 |
UniProt RGD Ensembl |
PMID:21099329 |
GO_REF:0000024 GO_REF:0000107 |
NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587
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G |
Ptpmt1 |
protein tyrosine phosphatase, mitochondrial 1 |
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IMP |
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RGD |
PMID:20167843 |
RGD:12904047 |
NCBI chr 3:76,889,922...76,899,427
Ensembl chr 3:76,889,922...76,899,427
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G |
Tbc1d1 |
TBC1 domain family member 1 |
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IMP |
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RGD |
PMID:28177704 |
RGD:150521607 |
NCBI chr14:43,936,820...44,135,133
Ensembl chr14:43,935,636...44,136,499
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G |
Ucp2 |
uncoupling protein 2 |
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IMP |
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RGD |
PMID:21172424 |
RGD:7204422 |
NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
involved_in |
ISO |
(PMID:11387233) |
RGD |
PMID:11387233 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Anxa5 |
annexin A5 |
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IMP |
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RGD |
PMID:15256781 |
RGD:10053690 |
NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Ffar4 |
free fatty acid receptor 4 |
involved_in |
ISS ISO |
GO_REF:0000024 (PMID:24663807) |
UniProt RGD |
PMID:24663807 |
GO_REF:0000024 |
NCBI chr 1:235,873,576...235,891,597
Ensembl chr 1:235,873,576...235,891,597
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G |
Gal |
galanin and GMAP prepropeptide |
involved_in |
ISO |
(PMID:8837218) |
RGD |
PMID:8837218 |
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NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Irs1 |
insulin receptor substrate 1 |
involved_in |
IMP |
PMID:12435589 |
BHF-UCL |
PMID:12435589 |
RGD:729325 |
NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Npy |
neuropeptide Y |
involved_in |
ISO |
(PMID:8837218) |
RGD |
PMID:8837218 |
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NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Term paths to the root
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