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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of biological process
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Accession:GO:0048519 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
Synonyms:exact_synonym: down regulation of biological process;   downregulation of biological process;   negative regulation of physiological process
 narrow_synonym: inhibition of biological process
 alt_id: GO:0043118


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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19336
    negative regulation of biological process 5556
      negative regulation of 3'-UTR-mediated mRNA stabilization 1
      negative regulation of DNA-binding transcription factor activity + 166
      negative regulation of GTPase activity 39
      negative regulation of action potential + 10
      negative regulation of adhesion of symbiont to host epithelial cell 0
      negative regulation of asexual reproduction + 0
      negative regulation of behavior + 27
      negative regulation of biomineralization + 29
      negative regulation of cell killing + 30
      negative regulation of cellular process + 4956
      negative regulation of cellular protein localization + 126
      negative regulation of circadian rhythm + 19
      negative regulation of coflocculation 0
      negative regulation of cohesin unloading 0
      negative regulation of developmental pigmentation + 1
      negative regulation of developmental process + 1096
      negative regulation of dosage compensation by inactivation of X chromosome 0
      negative regulation of entry of bacterium into host cell 1
      negative regulation of establishment of RNA localization to telomere 1
      negative regulation of establishment of protein localization + 216
      negative regulation of fibrinolysis 8
      negative regulation of growth + 269
      negative regulation of guanyl-nucleotide exchange factor activity + 8
      negative regulation of hemostasis + 50
      negative regulation of immune system process + 467
      negative regulation of interphase mitotic telomere clustering 0
      negative regulation of intracellular mRNA localization + 0
      negative regulation of lipid localization + 50
      negative regulation of locomotion + 358
      negative regulation of long-term synaptic depression 3
      negative regulation of long-term synaptic potentiation 12
      negative regulation of maintenance of permeability of blood-brain barrier 3
      negative regulation of membrane depolarization + 6
      negative regulation of membrane hyperpolarization 1
      negative regulation of metabolic process + 3059
      negative regulation of mitotic telomere tethering at nuclear periphery 0
      negative regulation of multi-organism process + 38
      negative regulation of multicellular organismal process + 1361
      negative regulation of nitrogen utilization + 0
      negative regulation of nuclear receptor transcription coactivator activity 1
      negative regulation of phosphorus utilization 0
      negative regulation of proteasome-activating ATPase activity 0
      negative regulation of protein localization to cell-cell junction + 0
      negative regulation of protein localization to presynapse 0
      negative regulation of receptor localization to synapse 1
      negative regulation of reproductive process + 74
      negative regulation of response to stimulus + 1634
      negative regulation of ribonucleoprotein complex localization + 0
      negative regulation of short-term synaptic potentiation 1
      negative regulation of signaling + 1405
      negative regulation of single-species biofilm formation + 2
      negative regulation of sulfur utilization 0
      negative regulation of telomerase RNA localization to Cajal body 0
      negative regulation of transport + 586
      negative regulation of viral process + 109
Path 2
Term Annotations click to browse term
  biological_process 19336
    biological regulation 13340
      regulation of biological process 12655
        negative regulation of biological process 5556
          negative regulation of 3'-UTR-mediated mRNA stabilization 1
          negative regulation of DNA-binding transcription factor activity + 166
          negative regulation of GTPase activity 39
          negative regulation of action potential + 10
          negative regulation of adhesion of symbiont to host epithelial cell 0
          negative regulation of asexual reproduction + 0
          negative regulation of behavior + 27
          negative regulation of biomineralization + 29
          negative regulation of cell killing + 30
          negative regulation of cellular process + 4956
          negative regulation of cellular protein localization + 126
          negative regulation of circadian rhythm + 19
          negative regulation of coflocculation 0
          negative regulation of cohesin unloading 0
          negative regulation of developmental pigmentation + 1
          negative regulation of developmental process + 1096
          negative regulation of dosage compensation by inactivation of X chromosome 0
          negative regulation of entry of bacterium into host cell 1
          negative regulation of establishment of RNA localization to telomere 1
          negative regulation of establishment of protein localization + 216
          negative regulation of fibrinolysis 8
          negative regulation of growth + 269
          negative regulation of guanyl-nucleotide exchange factor activity + 8
          negative regulation of hemostasis + 50
          negative regulation of immune system process + 467
          negative regulation of interphase mitotic telomere clustering 0
          negative regulation of intracellular mRNA localization + 0
          negative regulation of lipid localization + 50
          negative regulation of locomotion + 358
          negative regulation of long-term synaptic depression 3
          negative regulation of long-term synaptic potentiation 12
          negative regulation of maintenance of permeability of blood-brain barrier 3
          negative regulation of membrane depolarization + 6
          negative regulation of membrane hyperpolarization 1
          negative regulation of metabolic process + 3059
          negative regulation of mitotic telomere tethering at nuclear periphery 0
          negative regulation of multi-organism process + 38
          negative regulation of multicellular organismal process + 1361
          negative regulation of nitrogen utilization + 0
          negative regulation of nuclear receptor transcription coactivator activity 1
          negative regulation of phosphorus utilization 0
          negative regulation of proteasome-activating ATPase activity 0
          negative regulation of protein localization to cell-cell junction + 0
          negative regulation of protein localization to presynapse 0
          negative regulation of receptor localization to synapse 1
          negative regulation of reproductive process + 74
          negative regulation of response to stimulus + 1634
          negative regulation of ribonucleoprotein complex localization + 0
          negative regulation of short-term synaptic potentiation 1
          negative regulation of signaling + 1405
          negative regulation of single-species biofilm formation + 2
          negative regulation of sulfur utilization 0
          negative regulation of telomerase RNA localization to Cajal body 0
          negative regulation of transport + 586
          negative regulation of viral process + 109
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.