CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: quinolin-8-ol
Accession: CHEBI:48981
browse the term
Definition: A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.
Synonyms: related_synonym: 1-Azanaphthalene-8-ol; 8-Chinolinol; 8-Hydroxy-chinolin; 8-Hydroxyquinoline; 8-OQ; 8-Quinol; 8-quinolinol; Formula=C9H7NO; InChI=1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H; InChIKey=MCJGNVYPOGVAJF-UHFFFAOYSA-N; Oxyquinoline; SMILES=Oc1cccc2cccnc12
xref: CAS:148-24-3; Drug_Central:3290; KEGG:C19434; KEGG:D05321
xref_mesh: MESH:D015125
xref: MetaCyc:8-HYDROXYQUINOLINE; PDBeChem:HQY; PMID:16914038; PMID:24206710; PMID:24445658; PMID:26067700; PMID:8877786; PMID:8902522; PPDB:1354; Reaxys:114512; Wikipedia:8-Hydroxyquinoline
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ABCB5
ATP binding cassette subfamily B member 5
affects response to substance
EXP
ABCB5 gene SNP affects the susceptibility to Oxyquinoline
CTD
PMID:25622337
NCBI chr 7:20,615,667...20,757,008
Ensembl chr 7:20,615,667...20,777,038
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ABCG5
ATP binding cassette subfamily G member 5
decreases expression
EXP
Oxyquinoline results in decreased expression of ABCG5 mRNA
CTD
PMID:21632981
NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865
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ACAD11
acyl-CoA dehydrogenase family member 11
decreases expression
EXP
Oxyquinoline results in decreased expression of ACAD11 mRNA
CTD
PMID:21632981
NCBI chr 3:132,558,141...132,659,809
Ensembl chr 3:132,558,138...132,660,082
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ACAT2
acetyl-CoA acetyltransferase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of ACAT2 mRNA
CTD
PMID:21632981
NCBI chr 6:159,762,045...159,779,112
Ensembl chr 6:159,762,045...159,779,112
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ACSL3
acyl-CoA synthetase long chain family member 3
decreases expression
EXP
Oxyquinoline results in decreased expression of ACSL3 mRNA
CTD
PMID:21632981
NCBI chr 2:222,861,036...222,944,639
Ensembl chr 2:222,860,942...222,944,639
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ACY1
aminoacylase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of ACY1 mRNA
CTD
PMID:21632981
NCBI chr 3:51,983,535...51,989,197
Ensembl chr 3:51,983,340...51,989,197
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ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
decreases expression
EXP
Oxyquinoline results in decreased expression of ADH4 mRNA
CTD
PMID:21632981
NCBI chr 4:99,123,658...99,144,297
Ensembl chr 4:99,123,657...99,157,792
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ADM
adrenomedullin
decreases expression
EXP
Oxyquinoline results in decreased expression of ADM mRNA
CTD
PMID:21632981
NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397
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ADSS1
adenylosuccinate synthase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of ADSS1 mRNA
CTD
PMID:21632981
NCBI chr14:104,724,229...104,747,325
Ensembl chr14:104,724,174...104,747,325
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AGA
aspartylglucosaminidase
decreases expression
EXP
Oxyquinoline results in decreased expression of AGA mRNA
CTD
PMID:21632981
NCBI chr 4:177,430,774...177,442,437
Ensembl chr 4:177,430,774...177,442,437
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AKR1B10
aldo-keto reductase family 1 member B10
increases expression
EXP
Oxyquinoline results in increased expression of AKR1B10 mRNA
CTD
PMID:21632981 PMID:26198647
NCBI chr 7:134,527,567...134,541,412
Ensembl chr 7:134,527,567...134,541,412
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AKR1C1
aldo-keto reductase family 1 member C1
increases expression
EXP
Oxyquinoline results in increased expression of AKR1C1 mRNA
CTD
PMID:21632981
NCBI chr10:4,963,415...4,983,283
Ensembl chr10:4,963,253...4,983,283
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AKR1C2
aldo-keto reductase family 1 member C2
increases expression
EXP
Oxyquinoline results in increased expression of AKR1C2 mRNA
CTD
PMID:21632981 PMID:26198647
NCBI chr10:4,987,775...5,018,000
Ensembl chr10:4,987,775...5,018,031
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ALDH1L1
aldehyde dehydrogenase 1 family member L1
increases expression
EXP
Oxyquinoline results in increased expression of ALDH1L1 mRNA
CTD
PMID:21632981
NCBI chr 3:126,103,570...126,197,945
Ensembl chr 3:126,103,562...126,197,994
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AMDHD1
amidohydrolase domain containing 1
decreases expression
EXP
Oxyquinoline results in decreased expression of AMDHD1 mRNA
CTD
PMID:21632981
NCBI chr12:95,943,331...95,968,720
Ensembl chr12:95,943,331...95,968,720
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AMOT
angiomotin
increases expression
EXP
Oxyquinoline results in increased expression of AMOT mRNA
CTD
PMID:21632981
NCBI chr X:112,774,877...112,840,831
Ensembl chr X:112,774,503...112,840,831
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ANGPTL8
angiopoietin like 8
decreases expression
EXP
Oxyquinoline results in decreased expression of ANGPTL8 mRNA
CTD
PMID:21632981
NCBI chr19:11,239,619...11,241,943
Ensembl chr19:11,237,502...11,241,943
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ANKRD1
ankyrin repeat domain 1
increases expression
EXP
Oxyquinoline results in increased expression of ANKRD1 mRNA
CTD
PMID:21632981
NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
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ANKRD37
ankyrin repeat domain 37
decreases expression
EXP
Oxyquinoline results in decreased expression of ANKRD37 mRNA
CTD
PMID:21632981
NCBI chr 4:185,396,841...185,400,723
Ensembl chr 4:185,396,021...185,400,628
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APBB2
amyloid beta precursor protein binding family B member 2
decreases expression
EXP
Oxyquinoline results in decreased expression of APBB2 mRNA
CTD
PMID:21632981
NCBI chr 4:40,810,027...41,214,542
Ensembl chr 4:40,810,027...41,216,714
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APRG1
APRG1 tumor suppressor candidate
increases expression
EXP
Oxyquinoline results in increased expression of APRG1 mRNA
CTD
PMID:21632981
NCBI chr 3:37,381,077...37,435,497
Ensembl chr 3:37,381,062...37,440,186
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AQP3
aquaporin 3 (Gill blood group)
decreases expression
EXP
Oxyquinoline results in decreased expression of AQP3 mRNA
CTD
PMID:21632981
NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596
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ARG1
arginase 1
increases expression
EXP
Oxyquinoline results in increased expression of ARG1 mRNA
CTD
PMID:21632981
NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332
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ARG2
arginase 2
increases expression
EXP
Oxyquinoline results in increased expression of ARG2 mRNA
CTD
PMID:21632981
NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
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ARHGAP44
Rho GTPase activating protein 44
decreases expression
EXP
Oxyquinoline results in decreased expression of ARHGAP44 mRNA
CTD
PMID:21632981
NCBI chr17:12,789,498...12,991,643
Ensembl chr17:12,789,498...12,991,643
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ARID3A
AT-rich interaction domain 3A
increases expression
ISO
Oxyquinoline results in increased expression of ARID3A mRNA
CTD
PMID:15612046
NCBI chr19:925,732...975,939
Ensembl chr19:925,781...975,939
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ARRDC3
arrestin domain containing 3
decreases expression
EXP
Oxyquinoline results in decreased expression of ARRDC3 mRNA
CTD
PMID:21632981
NCBI chr 5:91,368,631...91,383,317
Ensembl chr 5:91,368,631...91,383,317
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ATP6V0A2
ATPase H+ transporting V0 subunit a2
decreases expression
EXP
Oxyquinoline results in decreased expression of ATP6V0A2 mRNA
CTD
PMID:21632981
NCBI chr12:123,712,353...123,761,755
Ensembl chr12:123,712,353...123,761,755
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AZGP1
alpha-2-glycoprotein 1, zinc-binding
increases expression
EXP
Oxyquinoline results in increased expression of AZGP1 mRNA
CTD
PMID:21632981
NCBI chr 7:99,966,730...99,976,031
Ensembl chr 7:99,966,720...99,976,042
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BHLHE40
basic helix-loop-helix family member e40
decreases expression
EXP
Oxyquinoline results in decreased expression of BHLHE40 mRNA
CTD
PMID:21632981
NCBI chr 3:4,979,437...4,985,323
Ensembl chr 3:4,979,437...4,985,323
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BMP2K
BMP2 inducible kinase
decreases expression
EXP
Oxyquinoline results in decreased expression of BMP2K mRNA
CTD
PMID:21632981
NCBI chr 4:78,776,350...78,916,365
Ensembl chr 4:78,776,342...78,916,365
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BPIFB2
BPI fold containing family B member 2
increases expression
EXP
Oxyquinoline results in increased expression of BPIFB2 mRNA
CTD
PMID:21632981
NCBI chr20:33,007,704...33,023,703
Ensembl chr20:33,007,704...33,023,703
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CARNMT1
carnosine N-methyltransferase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CARNMT1 mRNA
CTD
PMID:21632981
NCBI chr 9:74,980,790...75,028,430
Ensembl chr 9:74,980,790...75,028,423
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CASP1
caspase 1
increases expression
ISO
Oxyquinoline results in increased expression of CASP1 mRNA
CTD
PMID:15612046
NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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CCDC18
coiled-coil domain containing 18
decreases expression
EXP
Oxyquinoline results in decreased expression of CCDC18 mRNA
CTD
PMID:21632981
NCBI chr 1:93,179,913...93,278,730
Ensembl chr 1:93,179,919...93,278,730
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CCN1
cellular communication network factor 1
increases expression
EXP
Oxyquinoline results in increased expression of CCN1 mRNA
CTD
PMID:21632981
NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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CCNE2
cyclin E2
decreases expression
EXP
Oxyquinoline results in decreased expression of CCNE2 mRNA
CTD
PMID:21632981
NCBI chr 8:94,880,224...94,896,693
Ensembl chr 8:94,879,770...94,896,678
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CDC6
cell division cycle 6
decreases expression
EXP
Oxyquinoline results in decreased expression of CDC6 mRNA
CTD
PMID:21632981
NCBI chr17:40,287,879...40,304,657
Ensembl chr17:40,287,879...40,304,657
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CDC7
cell division cycle 7
decreases expression
EXP
Oxyquinoline results in decreased expression of CDC7 mRNA
CTD
PMID:21632981
NCBI chr 1:91,500,851...91,525,764
Ensembl chr 1:91,500,851...91,525,764
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CDC73
cell division cycle 73
decreases expression
EXP
Oxyquinoline results in decreased expression of CDC73 mRNA
CTD
PMID:21632981
NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815
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CDH1
cadherin 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CDH1 mRNA
CTD
PMID:21632981
NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
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CDKN1A
cyclin dependent kinase inhibitor 1A
increases expression
EXP
Oxyquinoline results in increased expression of CDKN1A mRNA
CTD
PMID:21632981
NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397
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CDO1
cysteine dioxygenase type 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CDO1 mRNA
CTD
PMID:21632981
NCBI chr 5:115,804,733...115,816,659
Ensembl chr 5:115,804,733...115,816,659
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CENPK
centromere protein K
decreases expression
EXP
Oxyquinoline results in decreased expression of CENPK mRNA
CTD
PMID:21632981
NCBI chr 5:65,495,624...65,563,168
Ensembl chr 5:65,517,766...65,563,168
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CENPS
centromere protein S
decreases expression
EXP
Oxyquinoline results in decreased expression of CENPS mRNA
CTD
PMID:21632981
NCBI chr 1:10,430,433...10,442,808
Ensembl chr 1:10,430,433...10,442,808
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CHAC2
ChaC glutathione specific gamma-glutamylcyclotransferase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of CHAC2 mRNA
CTD
PMID:21632981
NCBI chr 2:53,767,783...53,775,196
Ensembl chr 2:53,767,804...53,775,196
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CHST15
carbohydrate sulfotransferase 15
increases expression
EXP
Oxyquinoline results in increased expression of CHST15 mRNA
CTD
PMID:21632981
NCBI chr10:124,007,668...124,093,598
Ensembl chr10:124,007,668...124,093,598
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CLGN
calmegin
decreases expression
EXP
Oxyquinoline results in decreased expression of CLGN mRNA
CTD
PMID:21632981
NCBI chr 4:140,388,453...140,427,648
Ensembl chr 4:140,388,453...140,427,661
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CLHC1
clathrin heavy chain linker domain containing 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CLHC1 mRNA
CTD
PMID:21632981
NCBI chr 2:55,172,547...55,232,563
Ensembl chr 2:55,172,547...55,232,563
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CMTR2
cap methyltransferase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of CMTR2 mRNA
CTD
PMID:21632981
NCBI chr16:71,281,392...71,289,722
Ensembl chr16:71,281,389...71,289,715
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CPA6
carboxypeptidase A6
decreases expression
EXP
Oxyquinoline results in decreased expression of CPA6 mRNA
CTD
PMID:21632981
NCBI chr 8:67,422,038...67,746,360
Ensembl chr 8:67,422,038...67,746,378
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CREBRF
CREB3 regulatory factor
increases expression
EXP
Oxyquinoline results in increased expression of CREBRF mRNA
CTD
PMID:21632981
NCBI chr 5:173,056,352...173,139,284
Ensembl chr 5:173,056,352...173,139,284
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CSAD
cysteine sulfinic acid decarboxylase
decreases expression
EXP
Oxyquinoline results in decreased expression of CSAD mRNA
CTD
PMID:21632981
NCBI chr12:53,157,663...53,181,351
Ensembl chr12:53,157,663...53,180,925
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CSTA
cystatin A
decreases expression
EXP
Oxyquinoline results in decreased expression of CSTA mRNA
CTD
PMID:21632981
NCBI chr 3:122,325,248...122,341,969
Ensembl chr 3:122,325,248...122,341,969
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CYGB
cytoglobin
increases expression
EXP
Oxyquinoline results in increased expression of CYGB mRNA
CTD
PMID:21632981
NCBI chr17:76,527,356...76,551,193
Ensembl chr17:76,527,356...76,551,175
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CYP24A1
cytochrome P450 family 24 subfamily A member 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CYP24A1 mRNA
CTD
PMID:21632981
NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986
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CYP51A1
cytochrome P450 family 51 subfamily A member 1
decreases expression
EXP
Oxyquinoline results in decreased expression of CYP51A1 mRNA
CTD
PMID:21632981
NCBI chr 7:92,112,153...92,134,803
Ensembl chr 7:92,084,987...92,134,803
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DDIT4
DNA damage inducible transcript 4
decreases expression
EXP
Oxyquinoline results in decreased expression of DDIT4 mRNA
CTD
PMID:21632981
NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
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DEPP1
DEPP autophagy regulator 1
increases expression
EXP
Oxyquinoline results in increased expression of DEPP1 mRNA
CTD
PMID:21632981
NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809
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DHFR2
dihydrofolate reductase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of DHFR2 mRNA
CTD
PMID:21632981
NCBI chr 3:94,057,922...94,063,320
Ensembl chr 3:94,047,836...94,063,389
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DMXL1
Dmx like 1
decreases expression
EXP
Oxyquinoline results in decreased expression of DMXL1 mRNA
CTD
PMID:21632981
NCBI chr 5:119,071,027...119,249,127
Ensembl chr 5:119,037,772...119,249,138
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DNAJB9
DnaJ heat shock protein family (Hsp40) member B9
decreases expression
EXP
Oxyquinoline results in decreased expression of DNAJB9 mRNA
CTD
PMID:21632981
NCBI chr 7:108,569,874...108,574,850
Ensembl chr 7:108,569,867...108,574,850
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DNAJC3
DnaJ heat shock protein family (Hsp40) member C3
decreases expression
EXP
Oxyquinoline results in decreased expression of DNAJC3 mRNA
CTD
PMID:21632981
NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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DRAM1
DNA damage regulated autophagy modulator 1
increases expression
EXP
Oxyquinoline results in increased expression of DRAM1 mRNA
CTD
PMID:21632981
NCBI chr12:101,877,580...101,923,612
Ensembl chr12:101,877,580...102,012,130
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DSE
dermatan sulfate epimerase
increases expression
EXP
Oxyquinoline results in increased expression of DSE mRNA
CTD
PMID:21632981
NCBI chr 6:116,254,171...116,444,861
Ensembl chr 6:116,254,173...116,444,861
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E2F8
E2F transcription factor 8
decreases expression
EXP
Oxyquinoline results in decreased expression of E2F8 mRNA
CTD
PMID:21632981
NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620
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EED
embryonic ectoderm development
decreases expression
EXP
Oxyquinoline results in decreased expression of EED mRNA
CTD
PMID:21632981
NCBI chr11:86,244,753...86,287,615
Ensembl chr11:86,201,212...86,279,807
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EFCAB7
EF-hand calcium binding domain 7
decreases expression
EXP
Oxyquinoline results in decreased expression of EFCAB7 mRNA
CTD
PMID:21632981
NCBI chr 1:63,523,525...63,585,370
Ensembl chr 1:63,523,372...63,572,693
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EGFR
epidermal growth factor receptor
multiple interactions
EXP
[Copper binds to Oxyquinoline] which results in increased phosphorylation of EGFR protein
CTD
PMID:18346929
NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
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EGR1
early growth response 1
multiple interactions
ISO
[cupric acetate co-treated with Oxyquinoline] results in increased expression of EGR1 mRNA
CTD
PMID:10487485
NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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EMP3
epithelial membrane protein 3 (MAM blood group)
increases expression
EXP
Oxyquinoline results in increased expression of EMP3 mRNA
CTD
PMID:21632981
NCBI chr19:48,325,552...48,330,553
Ensembl chr19:48,321,310...48,330,559
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EOGT
EGF domain specific O-linked N-acetylglucosamine transferase
decreases expression
EXP
Oxyquinoline results in decreased expression of EOGT mRNA
CTD
PMID:21632981
NCBI chr 3:68,975,225...69,013,684
Ensembl chr 3:68,975,217...69,013,684
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EPS8L3
EPS8 signaling adaptor L3
increases expression
EXP
Oxyquinoline results in increased expression of EPS8L3 mRNA
CTD
PMID:21632981
NCBI chr 1:109,750,080...109,763,923
Ensembl chr 1:109,750,080...109,764,027
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ESM1
endothelial cell specific molecule 1
decreases expression
EXP
Oxyquinoline results in decreased expression of ESM1 mRNA
CTD
PMID:21632981
NCBI chr 5:54,977,867...54,985,593
Ensembl chr 5:54,977,867...55,022,671
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ETNPPL
ethanolamine-phosphate phospho-lyase
decreases expression
EXP
Oxyquinoline results in decreased expression of ETNPPL mRNA
CTD
PMID:21632981
NCBI chr 4:108,742,053...108,763,053
Ensembl chr 4:108,742,048...108,763,054
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ETV4
ETS variant transcription factor 4
increases expression
EXP
Oxyquinoline results in increased expression of ETV4 mRNA
CTD
PMID:21632981
NCBI chr17:43,527,846...43,546,340
Ensembl chr17:43,527,844...43,579,620
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F3
coagulation factor III, tissue factor
increases expression
EXP
Oxyquinoline results in increased expression of F3 protein
CTD
PMID:25569083
NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
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FABP5
fatty acid binding protein 5
decreases expression
ISO
Oxyquinoline results in decreased expression of FABP5 mRNA
CTD
PMID:15612046
NCBI chr 8:81,280,536...81,284,775
Ensembl chr 8:81,280,536...81,284,777
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FAM13A
family with sequence similarity 13 member A
decreases expression
EXP
Oxyquinoline results in decreased expression of FAM13A mRNA
CTD
PMID:21632981
NCBI chr 4:88,725,960...89,057,185
Ensembl chr 4:88,725,955...89,111,398
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FAM13C
family with sequence similarity 13 member C
decreases expression
EXP
Oxyquinoline results in decreased expression of FAM13C mRNA
CTD
PMID:21632981
NCBI chr10:59,246,129...59,363,181
Ensembl chr10:59,246,130...59,363,181
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FAM241A
family with sequence similarity 241 member A
decreases expression
EXP
Oxyquinoline results in decreased expression of FAM241A mRNA
CTD
PMID:21632981
NCBI chr 4:112,145,454...112,195,256
Ensembl chr 4:112,145,454...112,195,256
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FDPS
farnesyl diphosphate synthase
decreases expression
EXP
Oxyquinoline results in decreased expression of FDPS mRNA
CTD
PMID:21632981
NCBI chr 1:155,308,866...155,320,665
Ensembl chr 1:155,308,748...155,320,666
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FERRY3
FERRY endosomal RAB5 effector complex subunit 3
decreases expression
EXP
Oxyquinoline results in decreased expression of FERRY3 mRNA
CTD
PMID:21632981
NCBI chr12:4,487,735...4,538,469
Ensembl chr12:4,487,735...4,538,508
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FILIP1L
filamin A interacting protein 1 like
increases expression
EXP
Oxyquinoline results in increased expression of FILIP1L mRNA
CTD
PMID:21632981
NCBI chr 3:99,828,811...100,114,501
Ensembl chr 3:99,828,811...100,114,513
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FNIP2
folliculin interacting protein 2
increases expression
EXP
Oxyquinoline results in increased expression of FNIP2 mRNA
CTD
PMID:21632981
NCBI chr 4:158,769,026...158,908,050
Ensembl chr 4:158,769,026...158,908,050
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FOS
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions decreases expression
ISO EXP
[cupric acetate co-treated with Oxyquinoline] results in increased expression of FOS mRNA Oxyquinoline results in decreased expression of FOS mRNA
CTD
PMID:10487485 PMID:21632981
NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190
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FRK
fyn related Src family tyrosine kinase
decreases expression
EXP
Oxyquinoline results in decreased expression of FRK mRNA
CTD
PMID:21632981
NCBI chr 6:115,931,149...116,100,725
Ensembl chr 6:115,931,149...116,060,891
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FRY
FRY microtubule binding protein
increases expression
EXP
Oxyquinoline results in increased expression of FRY mRNA
CTD
PMID:21632981
NCBI chr13:32,031,774...32,299,125
Ensembl chr13:31,846,713...32,299,125
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FXYD1
FXYD domain containing ion transport regulator 1
increases expression
EXP
Oxyquinoline results in increased expression of FXYD1 mRNA
CTD
PMID:21632981
NCBI chr19:35,137,188...35,143,109
Ensembl chr19:35,138,824...35,143,109
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G6PC1
glucose-6-phosphatase catalytic subunit 1
increases expression
EXP
Oxyquinoline results in increased expression of G6PC1 mRNA
CTD
PMID:21632981
NCBI chr17:42,900,799...42,914,438
Ensembl chr17:42,900,797...42,914,438
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GATA6
GATA binding protein 6
decreases expression
EXP
Oxyquinoline results in decreased expression of GATA6 mRNA
CTD
PMID:21632981
NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
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GBP2
guanylate binding protein 2
increases expression
EXP
Oxyquinoline results in increased expression of GBP2 mRNA
CTD
PMID:21632981
NCBI chr 1:89,106,132...89,126,114
Ensembl chr 1:89,106,132...89,150,456
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GCKR
glucokinase regulator
increases expression
EXP
Oxyquinoline results in increased expression of GCKR mRNA
CTD
PMID:21632981
NCBI chr 2:27,496,839...27,523,684
Ensembl chr 2:27,496,839...27,523,684
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GCNT2
glucosaminyl (N-acetyl) transferase 2 (I blood group)
increases expression
ISO
Oxyquinoline results in increased expression of GCNT2 mRNA
CTD
PMID:15612046
NCBI chr 6:10,521,351...10,629,368
Ensembl chr 6:10,492,223...10,629,368
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GDAP1
ganglioside induced differentiation associated protein 1
decreases expression
EXP
Oxyquinoline results in decreased expression of GDAP1 mRNA
CTD
PMID:21632981
NCBI chr 8:74,350,403...74,488,872
Ensembl chr 8:74,320,613...74,518,007
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GINS4
GINS complex subunit 4
decreases expression
EXP
Oxyquinoline results in decreased expression of GINS4 mRNA
CTD
PMID:21632981
NCBI chr 8:41,529,261...41,545,030
Ensembl chr 8:41,529,218...41,545,030
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GOLGA8A
golgin A8 family member A
decreases expression
EXP
Oxyquinoline results in decreased expression of GOLGA8A mRNA
CTD
PMID:21632981
NCBI chr15:34,379,068...34,437,808
Ensembl chr15:34,378,935...34,437,808
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GPX8
glutathione peroxidase 8 (putative)
decreases expression
EXP
Oxyquinoline results in decreased expression of GPX8 mRNA
CTD
PMID:21632981
NCBI chr 5:55,160,171...55,167,297
Ensembl chr 5:55,160,167...55,167,297
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GRB7
growth factor receptor bound protein 7
increases expression
EXP
Oxyquinoline results in increased expression of GRB7 mRNA
CTD
PMID:21632981
NCBI chr17:39,737,938...39,747,285
Ensembl chr17:39,737,927...39,747,291
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GUF1
GTP binding elongation factor GUF1
decreases expression
EXP
Oxyquinoline results in decreased expression of GUF1 mRNA
CTD
PMID:21632981
NCBI chr 4:44,678,420...44,700,928
Ensembl chr 4:44,678,420...44,700,928
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H2BC8
H2B clustered histone 8
decreases expression
EXP
Oxyquinoline results in decreased expression of H2BC8 mRNA
CTD
PMID:21632981
NCBI chr 6:26,216,200...26,216,688
Ensembl chr 6:26,216,200...26,216,688
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HAL
histidine ammonia-lyase
decreases expression
EXP
Oxyquinoline results in decreased expression of HAL mRNA
CTD
PMID:21632981
NCBI chr12:95,972,662...95,996,344
Ensembl chr12:95,972,662...95,996,365
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HAMP
hepcidin antimicrobial peptide
decreases expression
EXP
Oxyquinoline results in decreased expression of HAMP mRNA
CTD
PMID:21632981
NCBI chr19:35,282,528...35,285,143
Ensembl chr19:35,280,716...35,285,143
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HAUS3
HAUS augmin like complex subunit 3
decreases expression
EXP
Oxyquinoline results in decreased expression of HAUS3 mRNA
CTD
PMID:21632981
NCBI chr 4:2,228,349...2,242,121
Ensembl chr 4:2,227,464...2,242,133
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HEATR3
HEAT repeat containing 3
decreases expression
EXP
Oxyquinoline results in decreased expression of HEATR3 mRNA
CTD
PMID:21632981
NCBI chr16:50,065,970...50,107,272
Ensembl chr16:50,065,967...50,107,272
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HECTD2
HECT domain E3 ubiquitin protein ligase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of HECTD2 mRNA
CTD
PMID:21632981
NCBI chr10:91,409,235...91,514,820
Ensembl chr10:91,409,280...91,514,829
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HEY1
hes related family bHLH transcription factor with YRPW motif 1
decreases expression
EXP
Oxyquinoline results in decreased expression of HEY1 mRNA
CTD
PMID:21632981
NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857
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HILPDA
hypoxia inducible lipid droplet associated
decreases expression
EXP
Oxyquinoline results in decreased expression of HILPDA mRNA
CTD
PMID:21632981
NCBI chr 7:128,455,878...128,458,418
Ensembl chr 7:128,455,849...128,458,418
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HIRA
histone cell cycle regulator
decreases expression
EXP
Oxyquinoline results in decreased expression of HIRA mRNA
CTD
PMID:21632981
NCBI chr22:19,330,698...19,431,733
Ensembl chr22:19,330,698...19,447,450
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HIVEP2
HIVEP zinc finger 2
increases expression
EXP
Oxyquinoline results in increased expression of HIVEP2 mRNA
CTD
PMID:21632981
NCBI chr 6:142,751,469...142,946,365
Ensembl chr 6:142,751,469...142,956,698
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HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
decreases expression
EXP
Oxyquinoline results in decreased expression of HMGCR mRNA
CTD
PMID:21632981
NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
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HMOX1
heme oxygenase 1
multiple interactions decreases expression
ISO EXP
[ferric chloride co-treated with Oxyquinoline] results in decreased expression of HMOX1 mRNA; [ferric chloride co-treated with Oxyquinoline] results in decreased expression of HMOX1 protein; [ferric chloride co-treated with Oxyquinoline] results in increased expression of HMOX1 mRNA; [ferric chloride co-treated with Oxyquinoline] results in increased expression of HMOX1 protein Oxyquinoline results in decreased expression of HMOX1 mRNA
CTD
PMID:15019574 PMID:21632981
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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HSPA1A
heat shock protein family A (Hsp70) member 1A
increases expression affects localization
EXP
Oxyquinoline results in increased expression of HSPA1A protein Oxyquinoline affects the localization of HSPA1A protein
CTD
PMID:16239242
NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
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HSPA8
heat shock protein family A (Hsp70) member 8
affects localization
EXP
Oxyquinoline affects the localization of HSPA8 protein
CTD
PMID:16239242
NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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ID3
inhibitor of DNA binding 3
decreases expression
EXP
Oxyquinoline results in decreased expression of ID3 mRNA
CTD
PMID:21632981
NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
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IFT70B
intraflagellar transport 70B
decreases expression
EXP
Oxyquinoline results in decreased expression of IFT70B mRNA
CTD
PMID:21632981
NCBI chr 2:177,548,998...177,552,796
Ensembl chr 2:177,548,998...177,552,796
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IGFBP1
insulin like growth factor binding protein 1
increases expression
EXP
Oxyquinoline results in increased expression of IGFBP1 mRNA
CTD
PMID:21632981
NCBI chr 7:45,888,488...45,893,660
Ensembl chr 7:45,888,360...45,893,660
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IGFBP3
insulin like growth factor binding protein 3
decreases expression
EXP
Oxyquinoline results in decreased expression of IGFBP3 mRNA
CTD
PMID:21632981
NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
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IL15
interleukin 15
increases expression
ISO
Oxyquinoline results in increased expression of IL15 mRNA
CTD
PMID:15612046
NCBI chr 4:141,636,583...141,733,987
Ensembl chr 4:141,636,583...141,733,987
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IL6ST
interleukin 6 cytokine family signal transducer
decreases expression
EXP
Oxyquinoline results in decreased expression of IL6ST mRNA
CTD
PMID:21632981
NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022
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INHBE
inhibin subunit beta E
decreases expression
EXP
Oxyquinoline results in decreased expression of INHBE mRNA
CTD
PMID:21632981
NCBI chr12:57,455,307...57,458,025
Ensembl chr12:57,452,323...57,459,280
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INTU
inturned planar cell polarity protein
decreases expression
EXP
Oxyquinoline results in decreased expression of INTU mRNA
CTD
PMID:21632981
NCBI chr 4:127,632,957...127,726,737
Ensembl chr 4:127,623,271...127,726,737
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IRAK1BP1
interleukin 1 receptor associated kinase 1 binding protein 1
decreases expression
EXP
Oxyquinoline results in decreased expression of IRAK1BP1 mRNA
CTD
PMID:21632981
NCBI chr 6:78,867,551...78,979,411
Ensembl chr 6:78,867,551...78,946,440
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ISX
intestine specific homeobox
increases expression
EXP
Oxyquinoline results in increased expression of ISX mRNA
CTD
PMID:21632981
NCBI chr22:35,066,158...35,087,387
Ensembl chr22:35,066,136...35,087,387
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[cupric acetate co-treated with Oxyquinoline] results in increased expression of JUN mRNA
CTD
PMID:10487485
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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KATNAL1
katanin catalytic subunit A1 like 1
affects response to substance
EXP
KATNAL1 gene SNP affects the susceptibility to Oxyquinoline
CTD
PMID:25622337
NCBI chr13:30,202,630...30,307,551
Ensembl chr13:30,202,630...30,307,551
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KBTBD8
kelch repeat and BTB domain containing 8
decreases expression
EXP
Oxyquinoline results in decreased expression of KBTBD8 mRNA
CTD
PMID:21632981
NCBI chr 3:66,998,307...67,011,210
Ensembl chr 3:66,998,307...67,011,210
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KCTD18
potassium channel tetramerization domain containing 18
decreases expression
EXP
Oxyquinoline results in decreased expression of KCTD18 mRNA
CTD
PMID:21632981
NCBI chr 2:200,488,958...200,510,068
Ensembl chr 2:200,488,958...200,519,784
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KYAT1
kynurenine aminotransferase 1
increases expression
EXP
Oxyquinoline results in increased expression of KYAT1 mRNA
CTD
PMID:21632981
NCBI chr 9:128,832,942...128,882,523
Ensembl chr 9:128,832,942...128,882,494 Ensembl chr 9:128,832,942...128,882,494
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LAPTM5
lysosomal protein transmembrane 5
increases expression
ISO
Oxyquinoline results in increased expression of LAPTM5 mRNA
CTD
PMID:15612046
NCBI chr 1:30,732,469...30,757,774
Ensembl chr 1:30,732,469...30,757,774
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LCN15
lipocalin 15
increases expression
EXP
Oxyquinoline results in increased expression of LCN15 mRNA
CTD
PMID:21632981
NCBI chr 9:136,759,634...136,764,518
Ensembl chr 9:136,759,634...136,766,255
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LEAP2
liver enriched antimicrobial peptide 2
decreases expression
EXP
Oxyquinoline results in decreased expression of LEAP2 mRNA
CTD
PMID:21632981
NCBI chr 5:132,873,668...132,875,046
Ensembl chr 5:132,873,444...132,875,046
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LEF1
lymphoid enhancer binding factor 1
decreases expression
ISO
Oxyquinoline results in decreased expression of LEF1 mRNA
CTD
PMID:15612046
NCBI chr 4:108,047,548...108,168,932
Ensembl chr 4:108,047,545...108,168,956
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LGALS3
galectin 3
decreases expression
EXP
Oxyquinoline results in decreased expression of LGALS3 mRNA
CTD
PMID:21632981
NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423
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LIF
LIF interleukin 6 family cytokine
increases expression
EXP
Oxyquinoline results in increased expression of LIF mRNA
CTD
PMID:26198647
NCBI chr22:30,240,453...30,246,759
Ensembl chr22:30,240,453...30,246,759
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LINC00597
long intergenic non-protein coding RNA 597
decreases expression
EXP
Oxyquinoline results in decreased expression of LINC00597 mRNA
CTD
PMID:21632981
NCBI chr15:77,223,893...77,225,404
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LIPG
lipase G, endothelial type
decreases expression
EXP
Oxyquinoline results in decreased expression of LIPG mRNA
CTD
PMID:21632981
NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185
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LOX
lysyl oxidase
decreases expression
EXP
Oxyquinoline results in decreased expression of LOX mRNA
CTD
PMID:21632981
NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413
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MACF1
microtubule actin crosslinking factor 1
decreases expression
EXP
Oxyquinoline results in decreased expression of MACF1 mRNA
CTD
PMID:21632981
NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177
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MALAT1
metastasis associated lung adenocarcinoma transcript 1
decreases expression
EXP
Oxyquinoline results in decreased expression of MALAT1 mRNA
CTD
PMID:21632981
NCBI chr11:65,497,738...65,506,516
Ensembl chr11:65,497,606...65,508,073
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MANF
mesencephalic astrocyte derived neurotrophic factor
decreases expression
EXP
Oxyquinoline results in decreased expression of MANF mRNA
CTD
PMID:21632981
NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397
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MAPK10
mitogen-activated protein kinase 10
increases expression
ISO
Oxyquinoline results in increased expression of MAPK10 mRNA
CTD
PMID:15612046
NCBI chr 4:86,010,405...86,594,074
Ensembl chr 4:85,990,007...86,594,625
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MASTL
microtubule associated serine/threonine kinase like
decreases expression
EXP
Oxyquinoline results in decreased expression of MASTL mRNA
CTD
PMID:21632981
NCBI chr10:27,154,479...27,187,953
Ensembl chr10:27,154,824...27,187,953
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MFSD8
major facilitator superfamily domain containing 8
decreases expression
EXP
Oxyquinoline results in decreased expression of MFSD8 mRNA
CTD
PMID:21632981
NCBI chr 4:127,917,732...127,965,963
Ensembl chr 4:127,917,799...127,966,034
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MIGA1
mitoguardin 1
decreases expression
EXP
Oxyquinoline results in decreased expression of MIGA1 mRNA
CTD
PMID:21632981
NCBI chr 1:77,779,649...77,879,540
Ensembl chr 1:77,779,624...77,879,540
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MIXL1
Mix paired-like homeobox
decreases expression
EXP
Oxyquinoline results in decreased expression of MIXL1 mRNA
CTD
PMID:21632981
NCBI chr 1:226,223,664...226,227,060
Ensembl chr 1:226,223,618...226,227,060
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MSMO1
methylsterol monooxygenase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of MSMO1 mRNA
CTD
PMID:21632981
NCBI chr 4:165,327,669...165,343,164
Ensembl chr 4:165,327,667...165,343,164
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MT1F
metallothionein 1F
decreases expression
EXP
Oxyquinoline results in decreased expression of MT1F mRNA
CTD
PMID:21632981
NCBI chr16:56,657,959...56,659,303
Ensembl chr16:56,657,731...56,660,698
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MT1G
metallothionein 1G
decreases expression
EXP
Oxyquinoline results in decreased expression of MT1G mRNA
CTD
PMID:21632981
NCBI chr16:56,666,730...56,668,065
Ensembl chr16:56,666,730...56,668,065
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NAP1L5
nucleosome assembly protein 1 like 5
decreases expression
EXP
Oxyquinoline results in decreased expression of NAP1L5 mRNA
CTD
PMID:21632981
NCBI chr 4:88,695,913...88,697,829
Ensembl chr 4:88,695,913...88,697,829
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NDRG1
N-myc downstream regulated 1
increases expression
EXP
Oxyquinoline results in increased expression of NDRG1 mRNA
CTD
PMID:21632981
NCBI chr 8:133,237,175...133,297,252
Ensembl chr 8:133,237,175...133,302,022
G
NEIL3
nei like DNA glycosylase 3
decreases expression
EXP
Oxyquinoline results in decreased expression of NEIL3 mRNA
CTD
PMID:21632981
NCBI chr 4:177,309,874...177,371,268
Ensembl chr 4:177,309,874...177,362,936
G
NFE2L2
NFE2 like bZIP transcription factor 2
increases expression
EXP
Oxyquinoline results in increased expression of NFE2L2 mRNA
CTD
PMID:26862668
NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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NKX6-2
NK6 homeobox 2
increases expression
ISO
Oxyquinoline results in increased expression of NKX6-2 mRNA
CTD
PMID:15612046
NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147
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NUPR1
nuclear protein 1, transcriptional regulator
increases expression
EXP
Oxyquinoline results in increased expression of NUPR1 mRNA
CTD
PMID:21632981
NCBI chr16:28,532,708...28,538,974
Ensembl chr16:28,532,708...28,539,008
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OLFML3
olfactomedin like 3
decreases expression
EXP
Oxyquinoline results in decreased expression of OLFML3 mRNA
CTD
PMID:21632981
NCBI chr 1:113,979,474...113,982,253
Ensembl chr 1:113,979,391...114,035,572
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OSGIN1
oxidative stress induced growth inhibitor 1
increases expression
EXP
Oxyquinoline results in increased expression of OSGIN1 mRNA
CTD
PMID:21632981
NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
G
PABPC1L
poly(A) binding protein cytoplasmic 1 like
decreases expression
EXP
Oxyquinoline results in decreased expression of PABPC1L mRNA
CTD
PMID:21632981
NCBI chr20:44,910,060...44,939,316
Ensembl chr20:44,910,060...44,959,035
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PABPN1
poly(A) binding protein nuclear 1
multiple interactions
EXP
Oxyquinoline inhibits the reaction [PABPN1 protein mutant form binds to PABPN1 protein mutant form]
CTD
PMID:16239242
NCBI chr14:23,321,457...23,326,163
Ensembl chr14:23,321,457...23,326,163
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PALLD
palladin, cytoskeletal associated protein
increases expression
EXP
Oxyquinoline results in increased expression of PALLD mRNA
CTD
PMID:21632981
NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457
G
PAQR3
progestin and adipoQ receptor family member 3
decreases expression
EXP
Oxyquinoline results in decreased expression of PAQR3 mRNA
CTD
PMID:21632981
NCBI chr 4:78,887,076...78,939,438
Ensembl chr 4:78,887,127...78,939,438
G
PCK1
phosphoenolpyruvate carboxykinase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of PCK1 mRNA
CTD
PMID:21632981
NCBI chr20:57,561,110...57,568,121
Ensembl chr20:57,561,080...57,568,121
G
PCOLCE2
procollagen C-endopeptidase enhancer 2
decreases expression
EXP
Oxyquinoline results in decreased expression of PCOLCE2 mRNA
CTD
PMID:21632981
NCBI chr 3:142,817,874...142,889,083
Ensembl chr 3:142,815,922...142,889,206
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PDGFRL
platelet derived growth factor receptor like
decreases expression
EXP
Oxyquinoline results in decreased expression of PDGFRL mRNA
CTD
PMID:21632981
NCBI chr 8:17,576,433...17,643,144
Ensembl chr 8:17,576,433...17,644,071
G
PDK1
pyruvate dehydrogenase kinase 1
decreases expression
EXP
Oxyquinoline results in decreased expression of PDK1 mRNA
CTD
PMID:21632981
NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
G
PDP2
pyruvate dehydrogenase phosphatase catalytic subunit 2
decreases expression
EXP
Oxyquinoline results in decreased expression of PDP2 mRNA
CTD
PMID:21632981
NCBI chr16:66,880,515...66,891,101
Ensembl chr16:66,878,589...66,895,754
G
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
decreases expression
EXP
Oxyquinoline results in decreased expression of PFKFB3 mRNA
CTD
PMID:21632981
NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644
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PGC
progastricsin
increases expression
EXP
Oxyquinoline results in increased expression of PGC mRNA
CTD
PMID:21632981
NCBI chr 6:41,736,711...41,747,397
Ensembl chr 6:41,736,711...41,754,109
G
PIGW
phosphatidylinositol glycan anchor biosynthesis class W
decreases expression
EXP
Oxyquinoline results in decreased expression of PIGW mRNA
CTD
PMID:21632981
NCBI chr17:36,534,987...36,539,303
Ensembl chr17:36,534,987...36,539,310
G
PLAC8
placenta associated 8
decreases expression
EXP
Oxyquinoline results in decreased expression of PLAC8 mRNA
CTD
PMID:21632981
NCBI chr 4:83,090,048...83,114,729
Ensembl chr 4:83,059,493...83,137,075
G
PLIN2
perilipin 2
decreases expression
EXP
Oxyquinoline results in decreased expression of PLIN2 mRNA
CTD
PMID:21632981
NCBI chr 9:19,108,388...19,127,492
Ensembl chr 9:19,108,375...19,149,290
G
PLK2
polo like kinase 2
increases expression
EXP
Oxyquinoline results in increased expression of PLK2 mRNA
CTD
PMID:21632981
NCBI chr 5:58,453,982...58,460,086
Ensembl chr 5:58,453,982...58,460,139
G
PLP1
proteolipid protein 1
decreases expression
EXP
Oxyquinoline results in decreased expression of PLP1 mRNA
CTD
PMID:21632981
NCBI chr X:103,776,506...103,792,619
Ensembl chr X:103,773,718...103,792,619
G
PLPPR1
phospholipid phosphatase related 1
increases expression
EXP
Oxyquinoline results in increased expression of PLPPR1 mRNA
CTD
PMID:21632981
NCBI chr 9:101,028,727...101,325,135
Ensembl chr 9:101,028,727...101,325,135
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PPP1R16A
protein phosphatase 1 regulatory subunit 16A
increases expression
EXP
Oxyquinoline results in increased expression of PPP1R16A mRNA
CTD
PMID:21632981
NCBI chr 8:144,477,982...144,502,121
Ensembl chr 8:144,477,969...144,502,121
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PPP1R1C
protein phosphatase 1 regulatory inhibitor subunit 1C
decreases expression
ISO
Oxyquinoline results in decreased expression of PPP1R1C mRNA
CTD
PMID:15612046
NCBI chr 2:181,954,480...182,131,385
Ensembl chr 2:181,954,241...182,131,398
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PPP1R3C
protein phosphatase 1 regulatory subunit 3C
decreases expression
EXP
Oxyquinoline results in decreased expression of PPP1R3C mRNA
CTD
PMID:21632981
NCBI chr10:91,628,442...91,633,071
Ensembl chr10:91,628,442...91,633,071
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PPP3R1
protein phosphatase 3 regulatory subunit B, alpha
decreases expression
EXP
Oxyquinoline results in decreased expression of PPP3R1 mRNA
CTD
PMID:21632981
NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
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PRORSD1P
prolyl-tRNA synthetase associated domain containing 1, pseudogene
decreases expression
EXP
Oxyquinoline results in decreased expression of PRORSD1P mRNA
CTD
PMID:21632981
NCBI chr 2:55,282,319...55,284,472
Ensembl chr 2:55,282,329...55,284,437 Ensembl chr 2:55,282,329...55,284,437
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PTCD2
pentatricopeptide repeat domain 2
decreases expression
EXP
Oxyquinoline results in decreased expression of PTCD2 mRNA
CTD
PMID:21632981
NCBI chr 5:72,320,373...72,368,395
Ensembl chr 5:72,320,367...72,368,395
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PTCHD4
patched domain containing 4
increases expression
EXP
Oxyquinoline results in increased expression of PTCHD4 mRNA
CTD
PMID:21632981
NCBI chr 6:47,856,673...48,111,197
Ensembl chr 6:47,856,673...48,111,197
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PTMS
parathymosin
increases expression
EXP
Oxyquinoline results in increased expression of PTMS mRNA
CTD
PMID:21632981
NCBI chr12:6,766,363...6,770,952
Ensembl chr12:6,765,516...6,770,952
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QPCT
glutaminyl-peptide cyclotransferase
decreases expression
EXP
Oxyquinoline results in decreased expression of QPCT mRNA
CTD
PMID:21632981
NCBI chr 2:37,344,630...37,373,322
Ensembl chr 2:37,342,827...37,373,322
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RABGAP1L
RAB GTPase activating protein 1 like
decreases expression
EXP
Oxyquinoline results in decreased expression of RABGAP1L mRNA
CTD
PMID:21632981
NCBI chr 1:174,159,520...174,995,308
Ensembl chr 1:174,159,410...174,995,308
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RADX
RPA1 related single stranded DNA binding protein, X-linked
decreases expression
EXP
Oxyquinoline results in decreased expression of RADX mRNA
CTD
PMID:21632981
NCBI chr X:106,611,978...106,679,439
Ensembl chr X:106,611,930...106,679,439
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RAG1
recombination activating 1
decreases expression
ISO
Oxyquinoline results in decreased expression of RAG1 mRNA
CTD
PMID:15612046
NCBI chr11:36,510,353...36,579,762
Ensembl chr11:36,510,372...36,593,156
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RBM24
RNA binding motif protein 24
increases expression
EXP
Oxyquinoline results in increased expression of RBM24 mRNA
CTD
PMID:21632981
NCBI chr 6:17,281,361...17,293,871
Ensembl chr 6:17,281,361...17,293,871
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REEP3
receptor accessory protein 3
decreases expression
EXP
Oxyquinoline results in decreased expression of REEP3 mRNA
CTD
PMID:21632981
NCBI chr10:63,521,401...63,625,128
Ensembl chr10:63,521,401...63,625,128
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RGCC
regulator of cell cycle
increases expression
EXP
Oxyquinoline results in increased expression of RGCC mRNA
CTD
PMID:21632981
NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871
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RNFT1
ring finger protein, transmembrane 1
decreases expression
EXP
Oxyquinoline results in decreased expression of RNFT1 mRNA
CTD
PMID:21632981
NCBI chr17:59,952,240...59,964,740
Ensembl chr17:59,952,240...59,964,761
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RPGRIP1L
RPGRIP1 like
decreases expression
EXP
Oxyquinoline results in decreased expression of RPGRIP1L mRNA
CTD
PMID:21632981
NCBI chr16:53,598,153...53,703,859
Ensembl chr16:53,598,153...53,703,938
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RSL1D1
ribosomal L1 domain containing 1
increases expression
EXP
Oxyquinoline results in increased expression of RSL1D1 mRNA
CTD
PMID:21632981
NCBI chr16:11,833,850...11,851,542
Ensembl chr16:11,833,850...11,851,580
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SDF2L1
stromal cell derived factor 2 like 1
decreases expression
EXP
Oxyquinoline results in decreased expression of SDF2L1 mRNA
CTD
PMID:21632981
NCBI chr22:21,642,302...21,644,299
Ensembl chr22:21,642,302...21,644,299
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SENP5
SUMO specific peptidase 5
decreases expression
EXP
Oxyquinoline results in decreased expression of SENP5 mRNA
CTD
PMID:21632981
NCBI chr 3:196,867,920...196,934,714
Ensembl chr 3:196,867,856...196,934,714
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SERPINA7
serpin family A member 7
increases expression
EXP
Oxyquinoline results in increased expression of SERPINA7 mRNA
CTD
PMID:21632981
NCBI chr X:106,032,435...106,038,727
Ensembl chr X:106,032,435...106,038,727
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SERPINE1
serpin family E member 1
decreases expression
EXP
Oxyquinoline results in decreased expression of SERPINE1 mRNA
CTD
PMID:21632981
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SGK2
serum/glucocorticoid regulated kinase 2
decreases expression
EXP
Oxyquinoline results in decreased expression of SGK2 mRNA
CTD
PMID:21632981
NCBI chr20:43,559,027...43,585,627
Ensembl chr20:43,558,968...43,588,237
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SLC16A6
solute carrier family 16 member 6
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC16A6 mRNA
CTD
PMID:21632981
NCBI chr17:68,267,026...68,291,479
Ensembl chr17:68,267,026...68,291,267
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SLC22A3
solute carrier family 22 member 3
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC22A3 mRNA
CTD
PMID:21632981
NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577
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SLC30A1
solute carrier family 30 member 1
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC30A1 mRNA
CTD
PMID:21632981
NCBI chr 1:211,571,568...211,579,161
Ensembl chr 1:211,571,568...211,579,161
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SLC30A10
solute carrier family 30 member 10
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC30A10 mRNA
CTD
PMID:21632981
NCBI chr 1:219,910,445...219,959,098
Ensembl chr 1:219,685,427...219,959,018
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SLC35B3
solute carrier family 35 member B3
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC35B3 mRNA
CTD
PMID:21632981
NCBI chr 6:8,411,435...8,435,567
Ensembl chr 6:8,411,435...8,435,561
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SLC35D1
solute carrier family 35 member D1
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC35D1 mRNA
CTD
PMID:21632981
NCBI chr 1:66,972,976...67,054,148
Ensembl chr 1:66,999,350...67,054,148
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SLC51A
solute carrier family 51 member A
decreases expression
EXP
Oxyquinoline results in decreased expression of SLC51A mRNA
CTD
PMID:21632981
NCBI chr 3:196,216,534...196,233,427
Ensembl chr 3:196,211,487...196,243,178
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SLCO4A1
solute carrier organic anion transporter family member 4A1
increases expression
EXP
Oxyquinoline results in increased expression of SLCO4A1 mRNA
CTD
PMID:21632981
NCBI chr20:62,642,503...62,690,740
Ensembl chr20:62,642,503...62,685,785
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SLF1
SMC5-SMC6 complex localization factor 1
decreases expression
EXP
Oxyquinoline results in decreased expression of SLF1 mRNA
CTD
PMID:21632981
NCBI chr 5:94,618,231...94,697,621
Ensembl chr 5:94,618,669...94,739,436
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SMIM13
small integral membrane protein 13
decreases expression
EXP
Oxyquinoline results in decreased expression of SMIM13 mRNA
CTD
PMID:21632981
NCBI chr 6:11,093,834...11,138,733
Ensembl chr 6:11,093,834...11,138,733
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SNHG29
small nucleolar RNA host gene 29
increases expression
EXP
Oxyquinoline results in increased expression of SNHG29 mRNA
CTD
PMID:21632981
NCBI chr17:16,438,987...16,470,648
Ensembl chr17:16,438,767...16,480,249
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SNU13
small nuclear ribonucleoprotein 13
decreases expression
ISO
Oxyquinoline results in decreased expression of SNU13 mRNA
CTD
PMID:15612046
NCBI chr22:41,673,933...41,690,480
Ensembl chr22:41,673,933...41,690,504
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SOD2
superoxide dismutase 2
multiple interactions
ISO
[ferric chloride co-treated with Oxyquinoline] results in decreased expression of SOD2 protein; [ferric chloride co-treated with Oxyquinoline] results in increased expression of SOD2 mRNA; [ferric chloride co-treated with Oxyquinoline] results in increased expression of SOD2 protein
CTD
PMID:15019574
NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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SORBS3
sorbin and SH3 domain containing 3
increases expression
EXP
Oxyquinoline results in increased expression of SORBS3 mRNA
CTD
PMID:21632981
NCBI chr 8:22,544,973...22,575,788
Ensembl chr 8:22,544,986...22,575,788
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SPA17
sperm autoantigenic protein 17
decreases expression
EXP
Oxyquinoline results in decreased expression of SPA17 mRNA
CTD
PMID:21632981
NCBI chr11:124,673,904...124,697,518
Ensembl chr11:124,673,844...124,697,518
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SPAG4
sperm associated antigen 4
decreases expression
EXP
Oxyquinoline results in decreased expression of SPAG4 mRNA
CTD
PMID:21632981
NCBI chr20:35,615,829...35,621,094
Ensembl chr20:35,615,829...35,621,094
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SPC25
SPC25 component of NDC80 kinetochore complex
decreases expression
EXP
Oxyquinoline results in decreased expression of SPC25 mRNA
CTD
PMID:21632981
NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
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SPIN4
spindlin family member 4
decreases expression
EXP
Oxyquinoline results in decreased expression of SPIN4 mRNA
CTD
PMID:21632981
NCBI chr X:63,347,228...63,351,332
Ensembl chr X:63,347,228...63,351,332
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SPON2
spondin 2
increases expression
EXP
Oxyquinoline results in increased expression of SPON2 mRNA
CTD
PMID:21632981
NCBI chr 4:1,166,932...1,208,844
Ensembl chr 4:1,166,932...1,208,962
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SRD5A3
steroid 5 alpha-reductase 3
decreases expression
EXP
Oxyquinoline results in decreased expression of SRD5A3 mRNA
CTD
PMID:21632981
NCBI chr 4:55,346,242...55,373,100
Ensembl chr 4:55,346,213...55,373,100
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SRXN1
sulfiredoxin 1
increases expression
EXP
Oxyquinoline results in increased expression of SRXN1 mRNA
CTD
PMID:21632981
NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
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SSUH2
ssu-2 homolog
increases expression
EXP
Oxyquinoline results in increased expression of SSUH2 mRNA
CTD
PMID:21632981
NCBI chr 3:8,619,386...8,681,927
Ensembl chr 3:8,619,386...8,745,040
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STIL
STIL centriolar assembly protein
decreases expression
EXP
Oxyquinoline results in decreased expression of STIL mRNA
CTD
PMID:21632981
NCBI chr 1:47,250,139...47,314,896
Ensembl chr 1:47,250,139...47,314,892
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STOM
stomatin
increases expression
EXP
Oxyquinoline results in increased expression of STOM mRNA
CTD
PMID:21632981
NCBI chr 9:121,338,987...121,370,250
Ensembl chr 9:121,338,987...121,370,304
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SULT2A1
sulfotransferase family 2A member 1
increases expression
EXP
Oxyquinoline results in increased expression of SULT2A1 mRNA
CTD
PMID:21632981
NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315
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TCFL5
transcription factor like 5
increases expression
ISO
Oxyquinoline results in increased expression of TCFL5 mRNA
CTD
PMID:15612046
NCBI chr20:62,841,005...62,861,822
Ensembl chr20:62,841,005...62,861,822
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TEX9
testis expressed 9
decreases expression
EXP
Oxyquinoline results in decreased expression of TEX9 mRNA
CTD
PMID:21632981
NCBI chr15:56,243,973...56,460,010
Ensembl chr15:56,243,971...56,445,997
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THAP2
THAP domain containing 2
increases expression
EXP
Oxyquinoline results in increased expression of THAP2 mRNA
CTD
PMID:21632981
NCBI chr12:71,664,301...71,680,644
Ensembl chr12:71,664,301...71,680,644
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TIMM8A
translocase of inner mitochondrial membrane 8A
decreases expression
EXP
Oxyquinoline results in decreased expression of TIMM8A mRNA
CTD
PMID:21632981
NCBI chr X:101,345,661...101,348,742
Ensembl chr X:101,345,661...101,348,742
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TM7SF2
transmembrane 7 superfamily member 2
decreases expression
EXP
Oxyquinoline results in decreased expression of TM7SF2 mRNA
CTD
PMID:21632981
NCBI chr11:65,111,872...65,116,230
Ensembl chr11:65,111,845...65,116,384
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TMCC1
transmembrane and coiled-coil domain family 1
increases expression
EXP
Oxyquinoline results in increased expression of TMCC1 mRNA
CTD
PMID:21632981
NCBI chr 3:129,647,792...129,893,711
Ensembl chr 3:129,647,792...129,893,711
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TMEM116
transmembrane protein 116
decreases expression
EXP
Oxyquinoline results in decreased expression of TMEM116 mRNA
CTD
PMID:21632981
NCBI chr12:111,931,282...112,013,219
Ensembl chr12:111,931,282...112,013,866
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TMEM128
transmembrane protein 128
decreases expression
EXP
Oxyquinoline results in decreased expression of TMEM128 mRNA
CTD
PMID:21632981
NCBI chr 4:4,235,542...4,248,223
Ensembl chr 4:4,235,542...4,248,223
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TNFAIP3
TNF alpha induced protein 3
increases expression
EXP
Oxyquinoline results in increased expression of TNFAIP3 mRNA
CTD
PMID:21632981
NCBI chr 6:137,866,349...137,883,312
Ensembl chr 6:137,867,214...137,883,314
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TNFSF10
TNF superfamily member 10
increases expression
EXP
Oxyquinoline results in increased expression of TNFSF10 mRNA
CTD
PMID:21632981
NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
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TP63
tumor protein p63
increases expression
ISO
Oxyquinoline results in increased expression of TRP63 mRNA
CTD
PMID:15612046
NCBI chr 3:189,596,746...189,897,276
Ensembl chr 3:189,631,389...189,897,276
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TRPV2
transient receptor potential cation channel subfamily V member 2
increases expression
ISO
Oxyquinoline results in increased expression of TRPV2 mRNA
CTD
PMID:15612046
NCBI chr17:16,415,571...16,437,003
Ensembl chr17:16,415,571...16,437,003
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TTR
transthyretin
increases expression
EXP
Oxyquinoline results in increased expression of TTR mRNA
CTD
PMID:21632981
NCBI chr18:31,591,877...31,598,821
Ensembl chr18:31,557,009...31,598,833
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TTYH3
tweety family member 3
increases expression
EXP
Oxyquinoline results in increased expression of TTYH3 mRNA
CTD
PMID:21632981
NCBI chr 7:2,631,986...2,664,802
Ensembl chr 7:2,631,961...2,664,802
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TUBA1A
tubulin alpha 1a
decreases expression
EXP
Oxyquinoline results in decreased expression of TUBA1A mRNA
CTD
PMID:21632981
NCBI chr12:49,184,795...49,189,080
Ensembl chr12:49,184,686...49,189,324
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TUBB1
tubulin beta 1 class VI
affects expression
EXP
Oxyquinoline affects the expression of TUBB1 mRNA
CTD
PMID:21632981
NCBI chr20:59,016,438...59,026,654
Ensembl chr20:59,019,429...59,026,654
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TUBE1
tubulin epsilon 1
decreases expression
EXP
Oxyquinoline results in decreased expression of TUBE1 mRNA
CTD
PMID:21632981
NCBI chr 6:112,070,663...112,087,482
Ensembl chr 6:112,070,663...112,087,529
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TXNIP
thioredoxin interacting protein
increases expression
EXP
Oxyquinoline results in increased expression of TXNIP mRNA
CTD
PMID:21632981
NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
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TYMSOS
TYMS opposite strand RNA
increases expression
EXP
Oxyquinoline results in increased expression of TYMSOS mRNA
CTD
PMID:21632981
NCBI chr18:649,620...658,291
Ensembl chr18:630,886...658,352
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UBD
ubiquitin D
increases expression
EXP
Oxyquinoline results in increased expression of UBD mRNA
CTD
PMID:21632981
NCBI chr 6:29,555,515...29,559,732
Ensembl chr 6:29,555,515...29,559,732
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UGT2B15
UDP glucuronosyltransferase family 2 member B15
increases metabolic processing
EXP
UGT2B15 protein results in increased metabolism of Oxyquinoline
CTD
PMID:7835232
NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652
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USP43
ubiquitin specific peptidase 43
decreases expression
EXP
Oxyquinoline results in decreased expression of USP43 mRNA
CTD
PMID:21632981
NCBI chr17:9,645,260...9,729,687
Ensembl chr17:9,644,698...9,729,687
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UTRN
utrophin
increases expression
EXP
Oxyquinoline results in increased expression of UTRN mRNA
CTD
PMID:21632981
NCBI chr 6:144,285,335...144,853,034
Ensembl chr 6:144,285,335...144,853,034
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YPEL3
yippee like 3
increases expression
EXP
Oxyquinoline results in increased expression of YPEL3 mRNA
CTD
PMID:21632981
NCBI chr16:30,092,314...30,096,213
Ensembl chr16:30,092,314...30,096,915
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ZBTB38
zinc finger and BTB domain containing 38
increases expression
EXP
Oxyquinoline results in increased expression of ZBTB38 mRNA
CTD
PMID:21632981
NCBI chr 3:141,324,186...141,449,792
Ensembl chr 3:141,324,213...141,449,792
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ZBTB8A
zinc finger and BTB domain containing 8A
decreases expression
EXP
Oxyquinoline results in decreased expression of ZBTB8A mRNA
CTD
PMID:21632981
NCBI chr 1:32,539,427...32,605,941
Ensembl chr 1:32,539,427...32,605,941
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ZFP69B
ZFP69 zinc finger protein B
decreases expression
EXP
Oxyquinoline results in decreased expression of ZFP69B mRNA
CTD
PMID:21632981
NCBI chr 1:40,450,064...40,463,715
Ensembl chr 1:40,450,102...40,463,718
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ZWINT
ZW10 interacting kinetochore protein
decreases expression
EXP
Oxyquinoline results in decreased expression of ZWINT mRNA
CTD
PMID:21632981
NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273
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