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Gene: TUBA1A (tubulin alpha 1a) Homo sapiens
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Symbol: TUBA1A
Name: tubulin alpha 1a
Description: Exhibits identical protein binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Localizes to cytoplasmic ribonucleoprotein granule; microtubule; and recycling endosome. Implicated in lissencephaly; microcephaly; and visual epilepsy. Biomarker of Down syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-tubulin 3; B-ALPHA-1; FLJ25113; hum-a-tub1; hum-a-tub2; LIS3; TUBA3; tubulin alpha-1A chain; tubulin alpha-3 chain; tubulin B-alpha-1; tubulin, alpha 1a; tubulin, alpha 3; tubulin, alpha, brain-specific
Orthologs:
Mus musculus (house mouse) : Tuba1a (tubulin, alpha 1A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tuba1a (tubulin, alpha 1A)  Alliance
Canis lupus familiaris (dog) : LOC610636 (tubulin alpha-1B chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tuba1a (tubulin alpha 1a)
Sus scrofa (pig) : TUBA1A (tubulin alpha 1a)
Chlorocebus sabaeus (African green monkey) : TUBA1A (tubulin alpha 1a)
more info ...
Related Pseudogenes: TUBA3GP   TUBAP6  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1249,184,795 - 49,189,080 (-)EnsemblGRCh38hg38GRCh38
GRCh381249,184,795 - 49,189,324 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,578,578 - 49,583,107 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,864,849 - 47,869,128 (-)NCBINCBI36hg18NCBI36
Celera1248,371,440 - 48,375,724 (-)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,609,646 - 46,614,178 (-)NCBIHuRef
CHM1_11249,544,342 - 49,548,875 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TUBA1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1607082
Created: 2007-04-29
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.