Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TMCC1 (transmembrane and coiled-coil domain family 1) Homo sapiens
Symbol: TMCC1
Name: transmembrane and coiled-coil domain family 1
Description: Exhibits protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including endosome fission; endosome membrane tubulation; and protein complex oligomerization. Localizes to the cytosol; endoplasmic reticulum-endosome membrane contact site; and rough endoplasmic reticulum; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686M0169; FLJ42680; transmembrane and coiled-coil domains 1; transmembrane and coiled-coil domains protein 1
Mus musculus (house mouse) : Tmcc1 (transmembrane and coiled coil domains 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tmcc1 (transmembrane and coiled-coil domain family 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmcc1 (transmembrane and coiled-coil domain family 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TMCC1 (transmembrane and coiled-coil domain family 1)
Canis lupus familiaris (dog) : TMCC1 (transmembrane and coiled-coil domain family 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmcc1 (transmembrane and coiled-coil domain family 1)
Sus scrofa (pig) : TMCC1 (transmembrane and coiled-coil domain family 1)
Chlorocebus sabaeus (African green monkey) : TMCC1 (transmembrane and coiled-coil domain family 1)
Heterocephalus glaber (naked mole-rat) : Tmcc1 (transmembrane and coiled-coil domain family 1)
more info ...
Related Pseudogenes: TMCC1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl3129,647,792 - 129,893,606 (-)EnsemblGRCh38hg38GRCh38
GRCh383129,647,792 - 129,893,711 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373129,366,635 - 129,612,419 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363130,849,325 - 131,081,999 (-)NCBINCBI36hg18NCBI36
Build 343130,850,239 - 130,889,780NCBI
Celera3127,793,335 - 128,039,062 (-)NCBI
Cytogenetic Map3q22.1NCBI
HuRef3126,749,431 - 126,995,723 (-)NCBIHuRef
CHM1_13129,329,666 - 129,575,432 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TMCC1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349742
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.